VRDN — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| FMR LLC | $305 029 074 | 16 604 740 | 11,87% | Actions |
| VANGUARD GROUP INC | $174 649 921 | 5 612 144 | 6,79% | Actions |
| BlackRock, Inc. | $157 090 835 | 8 551 488 | 6,11% | Actions |
| Bellevue Group AG | $123 665 169 | 6 731 909 | 4,81% | Actions |
| Paradigm Biocapital Advisors LP | $123 515 986 | 6 723 788 | 4,81% | Actions |
| Kynam Capital Management, LP | $118 557 720 | 6 453 877 | 4,61% | Actions |
| STATE STREET CORP | $112 515 809 | 6 124 976 | 4,38% | Actions |
| Fairmount Funds Management LLC | $93 520 347 | 5 090 928 | 3,64% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $84 076 918 | 4 576 860 | 3,27% | Actions |
| Deep Track Capital, LP | $65 998 634 | 3 592 740 | 2,57% | Actions |
| Venrock Adviser, LLC | $59 847 935 | 3 257 917 | 2,33% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $57 468 009 | 3 128 362 | 2,24% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $50 569 432 | 2 752 827 | 1,97% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $45 968 039 | 2 501 869 | 1,79% | Actions |
| Avoro Capital Advisors LLC | $45 925 000 | 2 500 000 | 1,79% | Actions |
| BAKER BROS. ADVISORS LP | $43 776 169 | 2 383 025 | 1,70% | Actions |
| Point72 Asset Management, L.P. | $43 044 731 | 2 343 208 | 1,67% | Actions |
| Caligan Partners LP | $40 303 431 | 2 193 981 | 1,57% | Actions |
| NOVO HOLDINGS A/S | $39 219 950 | 2 135 000 | 1,53% | Actions |
| TANG CAPITAL MANAGEMENT LLC | $32 930 540 | 1 792 626 | 1,28% | Actions |
| Fisher Asset Management, LLC | $32 163 113 | 1 750 850 | 1,25% | Actions |
| Candriam S.C.A. | $31 340 230 | 1 707 698 | 1,22% | Actions |
| GOLDMAN SACHS GROUP INC | $31 069 254 | 1 691 304 | 1,21% | Actions |
| First Turn Management, LLC | $30 677 900 | 1 670 000 | 1,19% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $29 607 274 | 1 611 521 | 1,15% | Actions |
| ALLIANCEBERNSTEIN L.P. | $27 220 459 | 1 391 639 | 1,06% | Actions |
| UBS Group AG | $26 247 845 | 1 428 843 | 1,02% | Actions |
| Parkman Healthcare Partners LLC | $25 306 071 | 1 377 576 | 0,98% | Actions |
| Balyasny Asset Management L.P. | $23 511 010 | 1 279 859 | 0,91% | Actions |
| D. E. Shaw & Co., Inc. | $21 717 418 | 1 182 222 | 0,84% | Actions |
| RICE HALL JAMES & ASSOCIATES, LLC | $21 601 393 | 1 175 906 | 0,84% | Actions |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $20 435 027 | 1 112 413 | 0,79% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $18 592 975 | 1 012 138 | 0,72% | Actions |
| Elmind Capital, LP | $18 093 182 | 984 931 | 0,70% | Actions |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $17 375 111 | 888 298 | 0,68% | Actions |
| BANK OF AMERICA CORP /DE/ | $17 347 618 | 944 345 | 0,67% | Actions |
| NORTHERN TRUST CORP | $15 862 330 | 863 491 | 0,62% | Actions |
| Eversept Partners, LP | $15 268 079 | 831 142 | 0,59% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $14 972 046 | 815 027 | 0,58% | Actions |
| Schonfeld Strategic Advisors LLC | $14 576 741 | 793 508 | 0,57% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $14 119 182 | 768 600 | 0,55% | Actions |
| MORGAN STANLEY | $13 388 384 | 728 817 | 0,52% | Actions |
| Woodline Partners LP | $12 876 066 | 700 929 | 0,50% | Actions |
| JPMORGAN CHASE & CO | $12 106 209 | 639 929 | 0,47% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $12 079 892 | 657 588 | 0,47% | Actions |
| PERCEPTIVE ADVISORS LLC | $10 690 973 | 581 980 | 0,42% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $9 939 235 | 541 058 | 0,39% | Actions |
| EMERALD ADVISERS, LLC | $9 870 715 | 537 328 | 0,38% | Actions |
| DEUTSCHE BANK AG\ | $8 870 414 | 482 875 | 0,35% | Actions |
| ALGERT GLOBAL LLC | $8 858 694 | 482 237 | 0,34% | Actions |
| Ikarian Capital, LLC | $7 807 251 | 425 000 | 0,30% | Actions |
| Yiheng Capital Management, L.P. | $7 356 524 | 400 464 | 0,29% | Actions |
| Jump Financial, LLC | $7 315 871 | 398 251 | 0,28% | Actions |
| EMERALD MUTUAL FUND ADVISERS TRUST | $7 266 180 | 395 546 | 0,28% | Actions |
| PANAGORA ASSET MANAGEMENT INC | $5 963 967 | 324 658 | 0,23% | Actions |
| XTX Topco Ltd | $5 054 781 | 275 165 | 0,20% | Actions |
| Bank of New York Mellon Corp | $4 924 265 | 268 060 | 0,19% | Actions |
| Blue Owl Capital Holdings LP | $4 776 200 | 260 000 | 0,19% | Actions |
| Affinity Asset Advisors, LLC | $4 592 500 | 250 000 | 0,18% | Actions |
| VOYA INVESTMENT MANAGEMENT LLC | $4 588 146 | 249 763 | 0,18% | Actions |
| TD Asset Management Inc | $4 328 082 | 235 606 | 0,17% | Actions |
| Nuveen, LLC | $3 659 856 | 199 230 | 0,14% | Actions |
| CAPITAL FUND MANAGEMENT S.A. | $3 634 467 | 197 848 | 0,14% | Actions |
| FIRST TRUST ADVISORS LP | $3 329 268 | 181 234 | 0,13% | Actions |
| Knott David M Jr | $3 324 970 | 181 000 | 0,13% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $3 312 993 | 180 348 | 0,13% | Actions |
| Squarepoint Ops LLC | $3 250 663 | 176 955 | 0,13% | Actions |
| Privium Fund Management B.V. | $3 187 489 | 173 516 | 0,12% | Actions |
| HighVista Strategies LLC | $2 937 087 | 159 885 | 0,11% | Actions |
| Swiss National Bank | $2 849 187 | 155 100 | 0,11% | Actions |
| CITIGROUP INC | $2 579 424 | 140 415 | 0,10% | Actions |
| CITADEL ADVISORS LLC | $2 555 267 | 139 100 | 0,10% | Option d'achat |
| F/m Investments LLC | $2 475 560 | 134 761 | 0,10% | Actions |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $2 469 939 | 134 455 | 0,10% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2 393 317 | 130 284 | 0,09% | Actions |
| AQR CAPITAL MANAGEMENT LLC | $2 338 520 | 127 301 | 0,09% | Actions |
| KVP Capital Advisors, LP | $2 296 250 | 125 000 | 0,09% | Actions |
| Lighthouse Investment Partners, LLC | $2 204 400 | 120 000 | 0,09% | Actions |
| RHUMBLINE ADVISERS | $2 162 997 | 117 747 | 0,08% | Actions |
| WELLS FARGO & COMPANY/MN | $2 122 893 | 115 563 | 0,08% | Actions |
| Russell Investments Group, Ltd. | $2 117 986 | 115 296 | 0,08% | Actions |
| ALPS ADVISORS INC | $2 049 578 | 111 572 | 0,08% | Actions |
| Rafferty Asset Management, LLC | $1 997 719 | 108 749 | 0,08% | Actions |
| J. Safra Sarasin Holding AG | $1 981 002 | 107 839 | 0,08% | Actions |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $1 862 975 | 101 414 | 0,07% | Actions |
| Invesco Ltd. | $1 853 441 | 100 895 | 0,07% | Actions |
| NOMURA HOLDINGS INC | $1 840 674 | 100 200 | 0,07% | Option d'achat |
| DIADEMA PARTNERS LP | $1 837 000 | 100 000 | 0,07% | Actions |
| Voleon Capital Management LP | $1 792 875 | 97 598 | 0,07% | Actions |
| Y-Intercept (Hong Kong) Ltd | $1 777 408 | 96 756 | 0,07% | Actions |
| Merck & Co., Inc. | $1 716 015 | 93 414 | 0,07% | Actions |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | $1 692 765 | 92 148 | 0,07% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1 679 055 | 91 402 | 0,07% | Actions |
| Caption Management, LLC | $1 580 555 | 86 040 | 0,06% | Actions |
| VICTORY CAPITAL MANAGEMENT INC | $1 499 525 | 81 629 | 0,06% | Actions |
| BARCLAYS PLC | $1 495 851 | 81 429 | 0,06% | Actions |
| Aquatic Capital Management LLC | $1 466 753 | 79 845 | 0,06% | Actions |
| Knights of Columbus Asset Advisors LLC | $1 296 059 | 70 553 | 0,05% | Actions |
| J. Goldman & Co LP | $1 239 975 | 67 500 | 0,05% | Option d'achat |
| Burkehill Global Management, LP | $1 194 050 | 65 000 | 0,05% | Actions |
| Legal & General Group Plc | $1 190 155 | 64 788 | 0,05% | Actions |
| TUDOR INVESTMENT CORP ET AL | $1 142 320 | 62 184 | 0,04% | Actions |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $1 117 740 | 60 846 | 0,04% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $1 008 789 | 54 915 | 0,04% | Actions |
| PROFUND ADVISORS LLC | $1 006 180 | 54 773 | 0,04% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $998 223 | 54 051 | 0,04% | Actions |
| MetLife Investment Management, LLC | $968 264 | 52 709 | 0,04% | Actions |
| Greenland Capital Management LP | $918 500 | 50 000 | 0,04% | Actions |
| SEVEN GRAND MANAGERS, LLC | $918 500 | 50 000 | 0,04% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $912 401 | 49 668 | 0,04% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $911 152 | 49 600 | 0,04% | Option de vente |
| Advisory Services Network, LLC | $879 188 | 47 860 | 0,03% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $856 042 | 46 600 | 0,03% | Option d'achat |
| Headlands Technologies LLC | $855 013 | 46 544 | 0,03% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $840 611 | 45 760 | 0,03% | Actions |
| Quadrature Capital Ltd | $828 083 | 45 078 | 0,03% | Actions |
| CITADEL ADVISORS LLC | $758 736 | 41 303 | 0,03% | Actions |
| Vanguard Global Advisers, LLC | $748 578 | 40 750 | 0,03% | Actions |
| Verdad Advisers, LP | $711 323 | 38 722 | 0,03% | Actions |
| DCF Advisers, LLC | $698 060 | 38 000 | 0,03% | Actions |
| DNB Asset Management AS | $657 187 | 35 775 | 0,03% | Actions |
| TWINBEECH CAPITAL LP | $646 624 | 35 200 | 0,03% | Actions |
| AlphaQuest LLC | $617 639 | 19 847 | 0,02% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $582 678 | 31 719 | 0,02% | Actions |
| CITADEL ADVISORS LLC | $573 144 | 31 200 | 0,02% | Option de vente |
| JANE STREET GROUP, LLC | $551 100 | 30 000 | 0,02% | Option d'achat |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $540 000 | 29 370 | 0,02% | Actions |
| AMERIPRISE FINANCIAL INC | $537 928 | 29 283 | 0,02% | Actions |
| JANUS HENDERSON GROUP PLC | $536 666 | 27 472 | 0,02% | Actions |
| INTECH INVESTMENT MANAGEMENT LLC | $521 947 | 28 413 | 0,02% | Actions |
| Police & Firemen's Retirement System of New Jersey | $489 395 | 26 641 | 0,02% | Actions |
| Persistent Asset Partners Ltd | $468 251 | 25 490 | 0,02% | Actions |
| Greenland Capital Management LP | $459 250 | 25 000 | 0,02% | Option d'achat |
| State of New Jersey Common Pension Fund D | $459 177 | 24 996 | 0,02% | Actions |
| SBI Okasan Asset Management Co.Ltd. | $417 138 | 22 200 | 0,02% | Actions |
| Quantinno Capital Management LP | $403 203 | 21 949 | 0,02% | Actions |
| 71 West Capital Partners | $393 118 | 21 400 | 0,02% | Actions |
| ARIZONA STATE RETIREMENT SYSTEM | $391 832 | 21 330 | 0,02% | Actions |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $387 056 | 21 070 | 0,02% | Actions |
| Virtus Investment Advisers, LLC | $367 620 | 20 012 | 0,01% | Actions |
| Bayforest Capital Ltd | $363 267 | 19 775 | 0,01% | Actions |
| Brevan Howard Capital Management LP | $358 233 | 19 501 | 0,01% | Actions |
| Creative Planning | $332 644 | 18 108 | 0,01% | Actions |
| KLP KAPITALFORVALTNING AS | $321 475 | 17 500 | 0,01% | Actions |
| Vanguard Investments Australia, Ltd. | $297 043 | 16 170 | 0,01% | Actions |
| E Fund Management Co., Ltd. | $281 686 | 15 334 | 0,01% | Actions |
| Graham Capital Management, L.P. | $281 502 | 15 324 | 0,01% | Actions |
| ALLSTATE CORP | $274 723 | 14 955 | 0,01% | Actions |
| PRUDENTIAL FINANCIAL INC | $271 325 | 14 770 | 0,01% | Actions |
| SEI INVESTMENTS CO | $266 980 | 14 535 | 0,01% | Actions |
| FEDERATED HERMES, INC. | $261 552 | 14 238 | 0,01% | Actions |
| Point72 Asset Management, L.P. | $238 810 | 13 000 | 0,01% | Option d'achat |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $221 910 | 12 080 | 0,01% | Actions |
| ProShare Advisors LLC | $217 226 | 11 825 | 0,01% | Actions |
| Glenmede Investment Management, LP | $214 505 | 9 940 | 0,01% | Actions |
| Corton Capital Inc. | $212 865 | 9 864 | 0,01% | Actions |
| NATIONS FINANCIAL GROUP INC, /IA/ /ADV | $207 067 | 11 272 | 0,01% | Actions |
| Pictet Asset Management Holding SA | $206 203 | 11 225 | 0,01% | Actions |
| VIRGINIA RETIREMENT SYSTEMS ET Al | $203 907 | 11 100 | 0,01% | Actions |
| Man Group plc | $197 294 | 10 740 | 0,01% | Actions |
| Ensign Peak Advisors, Inc | $185 537 | 10 100 | 0,01% | Actions |
| OpenArc Corporate Advisory, LLC | $184 398 | 10 038 | 0,01% | Actions |
| Greenland Capital Management LP | $183 700 | 10 000 | 0,01% | Option de vente |
| Velan Capital Investment Management LP | $183 700 | 10 000 | 0,01% | Actions |
| LMR Partners LLP | $183 700 | 10 000 | 0,01% | Actions |
| Caitong International Asset Management Co., Ltd | $159 360 | 8 675 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $150 597 | 8 198 | 0,01% | Actions |
| Larson Financial Group LLC | $142 955 | 7 782 | 0,01% | Actions |
| Eleva Capital SAS | $139 385 | 7 126 | 0,01% | Actions |
| Ghisallo Capital Management LLC | $128 590 | 7 000 | 0,01% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $105 599 | 5 748 410 | 0,00% | Actions |
| LAZARD ASSET MANAGEMENT LLC | $98 941 | 5 386 | 0,00% | Actions |
| Clearstead Advisors, LLC | $92 384 | 5 029 | 0,00% | Actions |
| STRS OHIO | $82 665 | 4 500 | 0,00% | Actions |
| OSAIC HOLDINGS, INC. | $61 317 | 3 338 | 0,00% | Actions |
| Tower Research Capital LLC (TRC) | $60 713 | 3 305 | 0,00% | Actions |
| ROYAL BANK OF CANADA | $53 000 | 2 909 | 0,00% | Actions |
| State of Wyoming | $42 747 | 2 327 | 0,00% | Actions |
| NISA INVESTMENT ADVISORS, LLC | $31 192 | 1 698 | 0,00% | Actions |
| Sterling Capital Management LLC | $30 531 | 1 662 | 0,00% | Actions |
| Federation des caisses Desjardins du Quebec | $30 035 | 1 635 | 0,00% | Actions |
| Kemnay Advisory Services Inc. | $17 543 | 955 | 0,00% | Actions |
| J.Safra Asset Management Corp | $17 488 | 952 | 0,00% | Actions |
| Allworth Financial LP | $11 482 | 625 | 0,00% | Actions |
| CWM, LLC | $10 523 | 538 | 0,00% | Actions |
| SBI Securities Co., Ltd. | $10 416 | 567 | 0,00% | Actions |
| Optiver Holding B.V. | $9 957 | 542 | 0,00% | Actions |
| COMERICA BANK | $9 542 | 307 | 0,00% | Actions |
| GAMMA Investing LLC | $8 487 | 462 | 0,00% | Actions |
| Farther Finance Advisors, LLC | $6 233 | 338 | 0,00% | Actions |
| Rockefeller Capital Management L.P. | $5 750 | 313 | 0,00% | Actions |
| IFG Advisory, LLC | $4 997 | 272 | 0,00% | Actions |
| SIMPLEX TRADING, LLC | $4 959 | 270 | 0,00% | Actions |
| ROTHSCHILD INVESTMENT LLC | $4 886 | 266 | 0,00% | Actions |
| Arax Advisory Partners | $4 372 | 238 | 0,00% | Actions |
| Quarry LP | $4 225 | 230 | 0,00% | Actions |
| EverSource Wealth Advisors, LLC | $4 097 | 223 | 0,00% | Actions |
| PNC Financial Services Group, Inc. | $4 078 | 222 | 0,00% | Actions |
| FIFTH THIRD BANCORP | $3 814 | 208 | 0,00% | Actions |
| US BANCORP \DE\ | $3 490 | 190 | 0,00% | Actions |
| Versant Capital Management, Inc | $3 047 | 148 | 0,00% | Actions |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | $2 772 | 150 | 0,00% | Actions |
| Smartleaf Asset Management LLC | $2 518 | 134 | 0,00% | Actions |
| Silver Grove Financial Group, Inc. | $2 131 | 116 | 0,00% | Actions |
| SJS Investment Consulting Inc. | $2 021 | 110 | 0,00% | Actions |
| SG Americas Securities, LLC | $2 004 | 109 073 | 0,00% | Actions |
| Ameritas Advisory Services, LLC | $1 470 | 80 | 0,00% | Actions |
| ZIONS BANCORPORATION, NATIONAL ASSOCIATION /UT/ | $1 359 | 74 | 0,00% | Actions |
| Elequin Capital, LP | $1 304 | 71 | 0,00% | Actions |
| Parkside Financial Bank & Trust | $1 286 | 70 | 0,00% | Actions |
| Parallel Advisors, LLC | $1 194 | 65 | 0,00% | Actions |
| GSA CAPITAL PARTNERS LLP | $903 | 49 177 | 0,00% | Actions |
| LRI Investments, LLC | $845 | 46 | 0,00% | Actions |
| Owl Creek Wealth Partners LLC | $827 | 45 | 0,00% | Actions |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | $707 | 38 465 | 0,00% | Actions |
| Essential Partners LLC | $569 | 31 | 0,00% | Actions |
| Torren Management, LLC | $411 | 21 | 0,00% | Actions |
| Wealth Enhancement Trust Services, Inc. | $367 | 20 | 0,00% | Actions |
| SIGNATUREFD, LLC | $349 | 19 | 0,00% | Actions |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | $252 | 13 692 | 0,00% | Actions |
| IFP Advisors, Inc | $184 | 10 | 0,00% | Actions |
| Pinnacle Wealth Planning Services, Inc. | $147 | 8 | 0,00% | Actions |
| KBC Group NV | $76 | 4 120 | 0,00% | Actions |
| Pacer Advisors, Inc. | $33 | 1 816 | 0,00% | Actions |
| BESSEMER GROUP INC | $7 | 355 | 0,00% | Actions |
| Covestor Ltd | $1 | 29 | 0,00% | Actions |