| RTW INVESTMENTS, LP |
$167,215,336 |
4,543,895 |
11.19% |
주식
|
| BlackRock, Inc. |
$117,813,765 |
3,201,461 |
7.88% |
주식
|
| MORGAN STANLEY |
$94,810,189 |
2,576,363 |
6.34% |
주식
|
| Kynam Capital Management, LP |
$89,578,818 |
2,434,207 |
5.99% |
주식
|
| Jefferies Financial Group Inc. |
$80,947,194 |
2,199,652 |
5.42% |
주식
|
| AMERICAN CENTURY COMPANIES INC |
$62,034,564 |
1,685,719 |
4.15% |
주식
|
| ACORN CAPITAL ADVISORS, LLC |
$61,581,856 |
1,673,420 |
4.12% |
주식
|
| Point72 Asset Management, L.P. |
$56,140,203 |
1,525,549 |
3.76% |
주식
|
| FRONTIER CAPITAL MANAGEMENT CO LLC |
$55,514,521 |
1,508,547 |
3.71% |
주식
|
| Opaleye Management Inc. |
$52,991,853 |
1,439,996 |
3.55% |
주식
|
| SILVERARC CAPITAL MANAGEMENT, LLC |
$47,912,827 |
1,301,979 |
3.21% |
주식
|
| MENORA MIVTACHIM HOLDINGS LTD. |
$42,413,141 |
1,152,531 |
2.84% |
주식
|
| D. E. Shaw & Co., Inc. |
$42,166,139 |
1,145,819 |
2.82% |
주식
|
| STATE STREET CORP |
$36,913,013 |
1,003,071 |
2.47% |
주식
|
| MPM BIOIMPACT LLC |
$34,349,672 |
933,415 |
2.30% |
주식
|
| Soleus Capital Management, L.P. |
$30,537,008 |
829,810 |
2.04% |
주식
|
| GOLDMAN SACHS GROUP INC |
$30,169,892 |
819,834 |
2.02% |
주식
|
| Migdal Insurance & Financial Holdings Ltd. |
$28,369,451 |
770,909 |
1.90% |
주식
|
| ORBIMED ADVISORS LLC |
$24,883,682 |
676,187 |
1.67% |
주식
|
| GEODE CAPITAL MANAGEMENT, LLC |
$22,461,394 |
610,364 |
1.50% |
주식
|
| Woodline Partners LP |
$18,426,717 |
500,726 |
1.23% |
주식
|
| Boxer Capital Management, LLC |
$18,400,000 |
500,000 |
1.23% |
주식
|
| BANK OF AMERICA CORP /DE/ |
$17,505,834 |
475,702 |
1.17% |
주식
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$16,801,334 |
456,558 |
1.12% |
주식
|
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND |
$14,244,323 |
387,074 |
0.95% |
주식
|
| NORTHERN TRUST CORP |
$11,208,175 |
304,570 |
0.75% |
주식
|
| RICE HALL JAMES & ASSOCIATES, LLC |
$11,063,920 |
300,650 |
0.74% |
주식
|
| VANGUARD GROUP INC |
$10,298,969 |
439,751 |
0.69% |
주식
|
| ADAR1 Capital Management, LLC |
$9,288,136 |
252,395 |
0.62% |
주식
|
| J. Goldman & Co LP |
$7,830,120 |
212,775 |
0.52% |
주식
|
| Privium Fund Management B.V. |
$7,728,000 |
210,000 |
0.52% |
주식
|
| FMR LLC |
$7,253,198 |
197,098 |
0.49% |
주식
|
| SUPERSTRING CAPITAL MANAGEMENT LP |
$7,040,318 |
191,313 |
0.47% |
주식
|
| Parkman Healthcare Partners LLC |
$6,405,555 |
174,064 |
0.43% |
주식
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$5,531,040 |
150,300 |
0.37% |
콜 옵션
|
| AQR CAPITAL MANAGEMENT LLC |
$5,491,591 |
149,228 |
0.37% |
주식
|
| TWO SIGMA INVESTMENTS, LP |
$5,481,838 |
148,963 |
0.37% |
주식
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$4,724,016 |
128,370 |
0.32% |
주식
|
| UBS Group AG |
$4,469,764 |
121,461 |
0.30% |
주식
|
| Elmind Capital, LP |
$4,416,000 |
120,000 |
0.30% |
주식
|
| WELLINGTON MANAGEMENT GROUP LLP |
$4,245,322 |
115,362 |
0.28% |
주식
|
| Bank of New York Mellon Corp |
$4,159,416 |
113,028 |
0.28% |
주식
|
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
$4,089,989 |
111,141 |
0.27% |
주식
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$4,084,800 |
111,000 |
0.27% |
풋 옵션
|
| Aisling Capital Management LP |
$3,974,400 |
108,000 |
0.27% |
주식
|
| MILLENNIUM MANAGEMENT LLC |
$3,926,266 |
106,692 |
0.26% |
주식
|
| ARK Investment Management LLC |
$3,735,494 |
101,508 |
0.25% |
주식
|
| Russell Investments Group, Ltd. |
$3,495,260 |
94,979 |
0.23% |
주식
|
| Nuveen, LLC |
$3,389,354 |
92,102 |
0.23% |
주식
|
| OAK RIDGE INVESTMENTS LLC |
$3,260,149 |
88,591 |
0.22% |
주식
|
| WELLS FARGO & COMPANY/MN |
$2,952,612 |
80,234 |
0.20% |
주식
|
| Informed Momentum Co LLC |
$2,917,173 |
79,271 |
0.20% |
주식
|
| Swiss National Bank |
$2,863,040 |
77,800 |
0.19% |
주식
|
| PANAGORA ASSET MANAGEMENT INC |
$2,724,083 |
74,024 |
0.18% |
주식
|
| TRUIST FINANCIAL CORP |
$2,660,125 |
72,286 |
0.18% |
주식
|
| VOYA INVESTMENT MANAGEMENT LLC |
$2,622,368 |
71,260 |
0.18% |
주식
|
| RENAISSANCE TECHNOLOGIES LLC |
$2,587,040 |
70,300 |
0.17% |
주식
|
| Ally Bridge Group (NY) LLC |
$2,545,934 |
69,183 |
0.17% |
주식
|
| RHUMBLINE ADVISERS |
$2,021,123 |
54,922 |
0.14% |
주식
|
| DEUTSCHE BANK AG\ |
$1,897,040 |
51,550 |
0.13% |
주식
|
| CITADEL ADVISORS LLC |
$1,865,760 |
50,700 |
0.12% |
콜 옵션
|
| Atom Investors LP |
$1,717,235 |
46,664 |
0.11% |
주식
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$1,654,123 |
44,949 |
0.11% |
주식
|
| BNP PARIBAS FINANCIAL MARKETS |
$1,604,443 |
43,599 |
0.11% |
주식
|
| JPMORGAN CHASE & CO |
$1,426,352 |
39,544 |
0.10% |
주식
|
| VANGUARD FIDUCIARY TRUST CO |
$1,369,218 |
37,207 |
0.09% |
주식
|
| Coastal Bridge Advisors, LLC |
$1,361,600 |
37,000 |
0.09% |
주식
|
| Legal & General Group Plc |
$1,318,543 |
35,830 |
0.09% |
주식
|
| STATE OF WISCONSIN INVESTMENT BOARD |
$1,289,987 |
35,054 |
0.09% |
주식
|
| J. Goldman & Co LP |
$1,251,200 |
34,000 |
0.08% |
콜 옵션
|
| Focus Partners Wealth |
$1,216,645 |
33,061 |
0.08% |
주식
|
| Schonfeld Strategic Advisors LLC |
$1,194,491 |
32,459 |
0.08% |
주식
|
| ALGERT GLOBAL LLC |
$1,190,480 |
32,350 |
0.08% |
주식
|
| AMERIPRISE FINANCIAL INC |
$1,165,383 |
31,668 |
0.08% |
주식
|
| POLEN CAPITAL MANAGEMENT LLC |
$1,089,832 |
29,615 |
0.07% |
주식
|
| Cetera Investment Advisers |
$1,065,434 |
28,952 |
0.07% |
주식
|
| VANGUARD ASSET MANAGEMENT, Ltd |
$956,947 |
26,004 |
0.06% |
주식
|
| Invesco Ltd. |
$954,113 |
25,927 |
0.06% |
주식
|
| HighVista Strategies LLC |
$918,822 |
24,968 |
0.06% |
주식
|
| MetLife Investment Management, LLC |
$915,032 |
24,865 |
0.06% |
주식
|
| Palo Alto Investors LP |
$901,600 |
24,500 |
0.06% |
주식
|
| JANE STREET GROUP, LLC |
$897,920 |
24,400 |
0.06% |
콜 옵션
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$852,594 |
47,419 |
0.06% |
주식
|
| CITIGROUP INC |
$841,653 |
22,871 |
0.06% |
주식
|
| ALLIANCEBERNSTEIN L.P. |
$785,906 |
43,710 |
0.05% |
주식
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$761,613 |
20,696 |
0.05% |
주식
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$718,925 |
19,536 |
0.05% |
주식
|
| JANE STREET GROUP, LLC |
$717,600 |
19,500 |
0.05% |
풋 옵션
|
| Susquehanna Portfolio Strategies, LLC |
$714,067 |
19,404 |
0.05% |
주식
|
| XTX Topco Ltd |
$713,405 |
19,386 |
0.05% |
주식
|
| FRANKLIN RESOURCES INC |
$708,878 |
19,263 |
0.05% |
주식
|
| Zurcher Kantonalbank (Zurich Cantonalbank) |
$677,046 |
18,398 |
0.05% |
주식
|
| Quantinno Capital Management LP |
$671,674 |
18,252 |
0.04% |
주식
|
| CAPITAL FUND MANAGEMENT S.A. |
$647,128 |
17,585 |
0.04% |
주식
|
| GLENMEDE TRUST CO NA |
$633,180 |
17,206 |
0.04% |
주식
|
| Toroso Investments, LLC |
$631,684 |
26,972 |
0.04% |
주식
|
| CITADEL ADVISORS LLC |
$610,880 |
16,600 |
0.04% |
풋 옵션
|
| Birchview Capital, LP |
$606,722 |
16,487 |
0.04% |
주식
|
| Engineers Gate Manager LP |
$602,710 |
16,378 |
0.04% |
주식
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$579,122 |
15,737 |
0.04% |
주식
|
| PARTNERS CAPITAL INVESTMENT GROUP, LLP |
$566,131 |
15,384 |
0.04% |
주식
|
| LPL Financial LLC |
$532,018 |
14,457 |
0.04% |
주식
|
| Verdad Advisers, LP |
$531,392 |
14,440 |
0.04% |
주식
|
| MML INVESTORS SERVICES, LLC |
$527,160 |
14,325 |
0.04% |
주식
|
| MAI Capital Management |
$521,198 |
14,163 |
0.03% |
주식
|
| CITADEL ADVISORS LLC |
$477,848 |
12,985 |
0.03% |
주식
|
| DNB Asset Management AS |
$474,941 |
12,906 |
0.03% |
주식
|
| State of New Jersey Common Pension Fund D |
$463,422 |
12,593 |
0.03% |
주식
|
| Police & Firemen's Retirement System of New Jersey |
$462,429 |
12,566 |
0.03% |
주식
|
| Creative Planning |
$444,360 |
12,075 |
0.03% |
주식
|
| Integrated Wealth Concepts LLC |
$432,069 |
11,741 |
0.03% |
주식
|
| Arax Advisory Partners |
$431,996 |
11,739 |
0.03% |
주식
|
| Squarepoint Ops LLC |
$430,523 |
11,699 |
0.03% |
주식
|
| WOLVERINE TRADING, LLC |
$415,338 |
21,700 |
0.03% |
콜 옵션
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$412,050 |
11,197 |
0.03% |
주식
|
| ROYAL BANK OF CANADA |
$407,000 |
11,060 |
0.03% |
주식
|
| Vanguard Investments Australia, Ltd. |
$398,176 |
10,820 |
0.03% |
주식
|
| ARIZONA STATE RETIREMENT SYSTEM |
$395,453 |
10,746 |
0.03% |
주식
|
| KLP KAPITALFORVALTNING AS |
$375,360 |
10,200 |
0.03% |
주식
|
| BARCLAYS PLC |
$374,439 |
10,175 |
0.03% |
주식
|
| Allianz Asset Management GmbH |
$371,680 |
10,100 |
0.02% |
주식
|
| Cresset Asset Management, LLC |
$366,749 |
9,966 |
0.02% |
주식
|
| INTECH INVESTMENT MANAGEMENT LLC |
$355,488 |
9,660 |
0.02% |
주식
|
| JANE STREET GROUP, LLC |
$349,784 |
9,505 |
0.02% |
주식
|
| Orion Porfolio Solutions, LLC |
$345,810 |
9,397 |
0.02% |
주식
|
| JANUS HENDERSON GROUP PLC |
$343,132 |
19,100 |
0.02% |
주식
|
| Vanguard Global Advisers, LLC |
$311,770 |
8,472 |
0.02% |
주식
|
| Main Street Financial Solutions, LLC |
$301,377 |
8,190 |
0.02% |
주식
|
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM |
$298,816 |
8,120 |
0.02% |
주식
|
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
$294,676 |
7,642 |
0.02% |
주식
|
| Baader Bank Aktiengesellschaft |
$294,400 |
8,000 |
0.02% |
주식
|
| FOX RUN MANAGEMENT, L.L.C. |
$292,818 |
7,957 |
0.02% |
주식
|
| China Universal Asset Management Co., Ltd. |
$285,347 |
7,754 |
0.02% |
주식
|
| DEBUSSY CAPITAL MANAGEMENT LP |
$281,585 |
15,661 |
0.02% |
주식
|
| Mariner, LLC |
$280,527 |
7,623 |
0.02% |
주식
|
| HAP Trading, LLC |
$271,342 |
19,806 |
0.02% |
주식
|
| Kathmere Capital Management, LLC |
$270,848 |
7,360 |
0.02% |
주식
|
| LOS ANGELES CAPITAL MANAGEMENT LLC |
$265,402 |
7,212 |
0.02% |
주식
|
| ProShare Advisors LLC |
$264,187 |
7,179 |
0.02% |
주식
|
| DIADEMA PARTNERS LP |
$262,642 |
7,137 |
0.02% |
주식
|
| Pictet Asset Management Holding SA |
$257,600 |
7,000 |
0.02% |
주식
|
| PRUDENTIAL FINANCIAL INC |
$256,680 |
6,975 |
0.02% |
주식
|
| Jain Global LLC |
$253,994 |
6,902 |
0.02% |
주식
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$249,578 |
6,782 |
0.02% |
주식
|
| Brookstone Capital Management |
$220,800 |
6,000 |
0.01% |
주식
|
| RITHOLTZ WEALTH MANAGEMENT |
$201,002 |
5,462 |
0.01% |
주식
|
| Nebula Research & Development LLC |
$162,249 |
11,843 |
0.01% |
주식
|
| Ameritas Investment Partners, Inc. |
$142,306 |
3,867 |
0.01% |
주식
|
| GROUP ONE TRADING LLC |
$112,093 |
3,046 |
0.01% |
주식
|
| OSAIC HOLDINGS, INC. |
$83,535 |
2,270 |
0.01% |
주식
|
| Tower Research Capital LLC (TRC) |
$82,837 |
2,251 |
0.01% |
주식
|
| Mirae Asset Global Investments Co., Ltd. |
$80,187 |
2,179 |
0.01% |
주식
|
| Quantbot Technologies LP |
$78,494 |
2,133 |
0.01% |
주식
|
| SG Americas Securities, LLC |
$75,547 |
2,052,906 |
0.01% |
주식
|
| CWM, LLC |
$70,014 |
3,894 |
0.00% |
주식
|
| Persistent Asset Partners Ltd |
$65,872 |
1,790 |
0.00% |
주식
|
| SIMPLEX TRADING, LLC |
$40,664 |
1,105 |
0.00% |
주식
|
| Activest Wealth Management |
$36,837 |
1,001 |
0.00% |
주식
|
| GF FUND MANAGEMENT CO. LTD. |
$36,542 |
993 |
0.00% |
주식
|
| FEDERATED HERMES, INC. |
$35,254 |
958 |
0.00% |
주식
|
| JONES FINANCIAL COMPANIES LLLP |
$34,540 |
1,000 |
0.00% |
주식
|
| Rossby Financial, LCC |
$28,336 |
770 |
0.00% |
주식
|
| Pinnacle Wealth Planning Services, Inc. |
$25,318 |
688 |
0.00% |
주식
|
| NISA INVESTMENT ADVISORS, LLC |
$21,896 |
595 |
0.00% |
주식
|
| EverSource Wealth Advisors, LLC |
$21,492 |
584 |
0.00% |
주식
|
| State of Wyoming |
$19,504 |
530 |
0.00% |
주식
|
| Larson Financial Group LLC |
$17,848 |
485 |
0.00% |
주식
|
| GAMMA Investing LLC |
$16,229 |
441 |
0.00% |
주식
|
| Napier Financial, LLC |
$14,720 |
400 |
0.00% |
주식
|
| NFSG Corp |
$12,880 |
350 |
0.00% |
주식
|
| CIBC Private Wealth Group LLC |
$10,155 |
509 |
0.00% |
주식
|
| Sterling Capital Management LLC |
$9,090 |
247 |
0.00% |
주식
|
| Allworth Financial LP |
$8,869 |
241 |
0.00% |
주식
|
| Costello Asset Management, INC |
$7,360 |
200 |
0.00% |
주식
|
| Rockefeller Capital Management L.P. |
$4,122 |
112 |
0.00% |
주식
|
| NewEdge Advisors, LLC |
$3,680 |
100 |
0.00% |
주식
|
| ROTHSCHILD INVESTMENT LLC |
$3,091 |
84 |
0.00% |
주식
|
| US BANCORP \DE\ |
$2,981 |
81 |
0.00% |
주식
|
| Optiver Holding B.V. |
$2,650 |
72 |
0.00% |
주식
|
| Smartleaf Asset Management LLC |
$2,597 |
72 |
0.00% |
주식
|
| PNC Financial Services Group, Inc. |
$2,502 |
68 |
0.00% |
주식
|
| Essential Partners LLC |
$1,766 |
48 |
0.00% |
주식
|
| Annandale Capital, LLC |
$1,672 |
45,425 |
0.00% |
주식
|
| Parkside Financial Bank & Trust |
$1,660 |
45 |
0.00% |
주식
|
| Altshuler Shaham Ltd |
$1,435 |
39 |
0.00% |
주식
|
| Quarry LP |
$1,325 |
36 |
0.00% |
주식
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$1,289 |
35,003 |
0.00% |
주식
|
| IFP Advisors, Inc |
$1,141 |
31 |
0.00% |
주식
|
| Farther Finance Advisors, LLC |
$883 |
24 |
0.00% |
주식
|
| DecisionPoint Financial, LLC |
$835 |
22 |
0.00% |
주식
|
| SIGNATUREFD, LLC |
$589 |
16 |
0.00% |
주식
|
| True Wealth Design, LLC |
$589 |
16 |
0.00% |
주식
|
| Jackson Creek Investment Advisors LLC |
$540 |
14,134 |
0.00% |
주식
|
| NATIONAL BANK OF CANADA /FI/ |
$405 |
11 |
0.00% |
주식
|
| SHIKIAR ASSET MANAGEMENT INC |
$322 |
8,750 |
0.00% |
주식
|
| ACADIAN ASSET MANAGEMENT LLC |
$297 |
8,113 |
0.00% |
주식
|
| SBI Securities Co., Ltd. |
$221 |
6 |
0.00% |
주식
|
| Silver Grove Financial Group, Inc. |
$147 |
4 |
0.00% |
주식
|
| Hughes Financial Services, LLC |
$110 |
3 |
0.00% |
주식
|
| Keating Financial Advisory Services, Inc. |
$74 |
2 |
0.00% |
주식
|
| KBC Group NV |
$49 |
1,340 |
0.00% |
주식
|
| Clearstead Advisors, LLC |
$37 |
1 |
0.00% |
주식
|
| Covestor Ltd |
$1 |
14 |
0.00% |
주식
|