ACHV Achieve Life Sciences, Inc. - Common Shares
$7.75
价格 · 八月 19, 2026
截至...的财报数据 八月 11, 2026
ACHV 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围
价格
$7.75
市值
—
P/E (TTM)
-4.0
每股收益 (TTM)
$-1.25
营收 (TTM)
—
股息收益率
—
ROE
—
负债/权益
—
52周区间
$3 – $8
ACHV 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图
Configure
10年表现 收入、净利润、利润率和每股收益趋势
营收与净利润
—
2018-12-31
→
2019-12-31
EPS
$-1.25
2020-12-31
→
2025-12-31
自由现金流
—
2016-12-31
→
2023-12-31
利润率
—
估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜？
指标
5年趋势
ACHV
同行中位数
P/E (TTM)
-4.0
134.0
盈利能力 毛利率、营业利润率和净利率；股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)
指标
5年趋势
ACHV
同行中位数
财务健康 债务、流动性、偿付能力 — 资产负债表强度
指标
5年趋势
ACHV
同行中位数
成长 营收、每股收益 (EPS) 和净利润增长：同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)
指标
5年趋势
ACHV
同行中位数
资本效率 资产周转率、库存周转率、应收账款周转率
指标
5年趋势
ACHV
同行中位数
ACHV 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间
买入
15 位分析师
- 强烈买入 3 20.0%
- 买入 11 73.3%
- 持有 1 6.7%
- 卖出 0 0.0%
- 强烈卖出 0 0.0%
12个月价格目标
12 位分析师 · 2026-08-16
中位数
$12.50
平均值
$13.83
← 低于所有目标
$7.75
最低
$9.00
最高
$21.00
中位数目标
$12.50
+61.3%
平均目标
$13.83
+78.5%
收益历史 每股收益实际值 vs 预估值，惊喜%，达标率，下次财报日期
平均惊喜
0.01%
| 期间 | EPS Actual | EPS 预期 | 惊喜 |
|---|---|---|---|
| 2026年3月31日 | $-0.19 | $-0.31 | 0.12% |
| 2025年12月31日 | $-0.28 | $-0.28 | -0.00% |
| 2025年9月30日 | $-0.28 | $-0.26 | -0.02% |
| 2025年6月30日 | $-0.37 | $-0.37 | 0.00% |
| 2025年3月31日 | $-0.37 | $-0.37 | 0.00% |
| 2024年12月31日 | $-0.36 | $-0.33 | -0.03% |
同行比较（GICS 子行业） 关键指标与行业同行对比
| 股票代码 | 市值 | P/E | 营收同比增长 | 净利润率 | ROE | 毛利率 |
|---|---|---|---|---|---|---|
| ACHV | — | -4.0 | — | — | — | — |
| IMMX | $277M | -5.9 | — | — | -59.8% | — |
| FTH | — | — | — | — | — | — |
| FDMT | $432M | -3.1 | 230194.6% | -164.4% | -30.2% | — |
| RIGL | $784M | 2.2 | 64.1% | 124.7% | 155.1% | — |
| AURA | $347M | -3.1 | -29.7% | -1601.4% | -68.2% | — |
| MNPR | — | — | — | — | — | — |
| CTMX | $725M | — | -44.8% | -22.8% | -15.9% | — |
| RGNX | $733M | -3.8 | 104.5% | -113.8% | -122.5% | — |
| BBOT | $1.00B | -2.9 | — | — | -146.2% | — |
完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表
损益表 13
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | · | $0 | $0 | |
| R&D Expense | · | $23M | $16M | $30M | $24M | $7M | $10M | $6M | |
| SG&A Expense | · | $16M | $11M | $11M | $9M | $8M | $7M | $7M | |
| Operating Expenses | $55M | $39M | $27M | $41M | $33M | $15M | $17M | $13M | |
| Interest Expense | · | · | $3M | $2M | · | · | · | · | |
| Interest Income | $1M | $2M | $825.0K | $199.0K | $17.0K | $69.0K | $170.0K | $171.0K | |
| Other Non-op | $-36.0K | $-30.0K | $-9.0K | $40.0K | $-75.0K | $-49.0K | $-37.0K | $-45.0K | |
| Pretax Income | $-55M | $-40M | $-30M | $-42M | $-33M | $-15M | $-16M | $-13M | |
| Net Income | $-55M | $-40M | $-30M | $-42M | $-33M | $-15M | $-16M | $-13M | |
| EPS (Basic) | $-1.25 | $-1.24 | $-1.50 | $-4.00 | $-4.08 | $-5.42 | · | · | |
| EPS (Diluted) | $-1.25 | $-1.24 | $-1.50 | $-4.00 | $-4.08 | $-5.42 | · | · | |
| Shares (Basic) | 43,594,652 | 32,071,146 | 19,827,534 | 10,593,034 | 8,119,836 | 2,718,909 | · | · | |
| Shares (Diluted) | 43,594,652 | 32,071,146 | 19,827,534 | 10,593,034 | 8,119,836 | 2,718,909 | · | · |
资产负债表 22
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $21M | $13M | $16M | $25M | $43M | $36M | $17M | $10M | |
| Short-term Investments | $15M | $22M | · | · | · | · | · | $5M | |
| Receivables | · | · | · | · | · | · | $8.0K | $7.0K | |
| Prepaid Expense | · | $2M | $1M | $2M | $1M | $1M | $670.0K | $926.0K | |
| Current Assets | $40M | $36M | $17M | $27M | $45M | $37M | $17M | $16M | |
| PP&E (Net) | $3.0K | $8.0K | $13.0K | $4.0K | $15.0K | $42.0K | $57.0K | $35.0K | |
| PP&E (Gross) | $256.0K | $256.0K | $256.0K | $303.0K | $302.0K | $674.0K | $657.0K | $755.0K | |
| Accum. Depreciation | $253.0K | $248.0K | $243.0K | $299.0K | $287.0K | $632.0K | $600.0K | $720.0K | |
| Goodwill | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | |
| Intangibles | $751.0K | $974.0K | $1M | $1M | $2M | $2M | $2M | $2M | |
| Other Non-current Assets | · | · | · | · | · | $187.0K | $187.0K | $118.0K | |
| Total Assets | $42M | $39M | $19M | $30M | $48M | $40M | $21M | $19M | |
| Accounts Payable | · | $2M | $618.0K | $2M | $841.0K | $332.0K | $859.0K | $144.0K | |
| Current Liabilities | $9M | $7M | $21M | $22M | $5M | $3M | $3M | $3M | |
| Capital Leases | $5.0K | $66.0K | $6.0K | $69.0K | $4.0K | $77.0K | $159.0K | $12.0K | |
| Total Liabilities | $20M | $18M | $21M | $22M | $19M | $3M | $3M | $3M | |
| Common Stock | $121.0K | $103.0K | $90.0K | $87.0K | $79.0K | $76.0K | $41.0K | $18.0K | |
| Retained Earnings | $-260M | $-206M | $-166M | $-136M | $-94M | $-60M | $-46M | $-25M | |
| AOCI | $10.0K | $31.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | |
| Stockholders' Equity | $22M | $21M | $-1M | $8M | $28M | $37M | $18M | $16M | |
| Liabilities + Equity | $42M | $39M | $19M | $30M | $48M | $40M | $21M | $19M | |
| Shares Outstanding | 53,233,988 | 34,685,072 | 21,165,760 | 17,897,029 | 9,453,542 | 6,111,735 | 1,474,258 | 6,721,117 |
现金流 10
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| D&A | $228.0K | $229.0K | $228.0K | $236.0K | $250.0K | $255.0K | · | · | |
| Stock-based Comp | $9M | $5M | $3M | $3M | $2M | $1M | $1M | $854.0K | |
| Amort. of Intangibles | $200.0K | $200.0K | $200.0K | $200.0K | $200.0K | $200.0K | $200.0K | $200.0K | |
| Operating Cash Flow | $-49M | $-30M | $-24M | $-38M | $-29M | $-13M | $-15M | $-11M | |
| CapEx | $3.0K | · | $21.0K | · | · | $17.0K | $53.0K | $46.0K | |
| Investing Cash Flow | $6M | $-22M | $-21.0K | · | · | $-17.0K | $5M | $-5M | |
| Financing Cash Flow | $52M | $49M | $15M | $19M | $37M | $33M | $17M | $20M | |
| Net Change in Cash | $8M | $-3M | $-9M | $-18M | $7M | $19M | $7M | $4M | |
| Taxes Paid | $0 | $0 | $0 | · | · | · | · | · | |
| Free Cash Flow | · | · | $-24M | · | · | $-13M | $-15M | $-11M |
盈利能力 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| ROA | · | -137.3% | -120.8% | · | -75.5% | -48.0% | -81.6% | -87.6% | |
| ROE | · | -152.4% | -2302.3% | · | -105.7% | -46.8% | -125.2% | -84.7% |
流动性与偿付能力 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | · | 5.5 | 0.8 | · | 9.8 | 12.6 | 6.0 | 4.8 | |
| Quick Ratio | · | 5.1 | 0.7 | · | 9.5 | 12.2 | 5.8 | 4.5 |
效率 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | · | 0.0 | 0.0 | |
| Receivables Turnover | · | · | · | · | · | · | 0.0 | 0.0 |
估值 (TTM) 9
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | · | · | · | · | · | · | $0 | $0 | |
| Net Income TTM | $-55M | $-40M | $-30M | $-42M | $-33M | $-15M | $-16M | $-13M | |
| Market Cap | · | $122M | $87M | · | $74M | $50M | $313M | $163M | |
| P/E | -4.0 | -2.8 | -2.7 | -0.6 | -1.9 | -1.5 | · | · | |
| P/B | · | 5.8 | -60.2 | · | 2.6 | 1.3 | 17.3 | 10.3 | |
| P / Tangible Book | 13.4 | 6.5 | · | 7.5 | 2.9 | 1.4 | · | · | |
| P / Cash Flow | · | -4.1 | -3.6 | · | -2.5 | -3.7 | -20.5 | -15.3 | |
| P / FCF | · | · | -3.6 | · | · | -3.7 | -20.5 | -15.2 | |
| Earnings Yield | -25.1% | -35.2% | -36.4% | -163.3% | -52.4% | -66.9% | · | · |
损益表 11
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | · | · | · | $5M | $7M | $7M | · | $8M | $5M | $3M | $4M | $5M | $6M | $10M | $7M | $4M | |
| SG&A Expense | · | · | · | $9M | $6M | $6M | · | $5M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | |
| Operating Expenses | $18M | $10M | $15M | $15M | $13M | $13M | $12M | $12M | $8M | $6M | $7M | $8M | $9M | $13M | $10M | $7M | |
| Interest Expense | · | · | · | · | · | · | · | $366.0K | $804.0K | $813.0K | $781.0K | $712.0K | $573.0K | $481.0K | $404.0K | $357.0K | |
| Interest Income | $1M | $297.0K | $427.0K | $554.0K | $192.0K | $322.0K | $482.0K | $673.0K | $833.0K | $368.0K | $262.0K | $193.0K | $162.0K | $73.0K | $4.0K | $4.0K | |
| Other Non-op | $-5.0K | $-13.0K | $7.0K | $-5.0K | $-59.0K | $21.0K | $-5.0K | $-8.0K | $-2.0K | $-15.0K | $-17.0K | $-6.0K | $-3.0K | $-30.0K | $5.0K | $6.0K | |
| Net Income | $-75M | $-10M | $-15M | $-14M | $-13M | $-13M | $-12M | $-13M | $-8M | $-6M | $-7M | $-8M | $-9M | $-13M | $-10M | $-8M | |
| EPS (Basic) | $-0.80 | $-0.19 | $-0.23 | $-0.28 | $-0.37 | $-0.37 | $-0.37 | $-0.36 | $-0.25 | $-0.26 | $-0.34 | $-0.43 | $-0.50 | $-1.35 | $-1.08 | $-0.80 | |
| EPS (Diluted) | $-0.80 | $-0.19 | $-0.23 | $-0.28 | $-0.37 | $-0.37 | $-0.37 | $-0.36 | $-0.25 | $-0.26 | $-0.34 | $-0.43 | $-0.50 | $-1.35 | $-1.08 | $-0.80 | |
| Shares (Basic) | 93,510,544 | 53,381,989 | -76,793,154 | 51,017,662 | 34,685,072 | 34,685,072 | -61,650,747 | 34,355,050 | 34,318,709 | 25,048,134 | 21,127,281 | 19,048,627 | 17,917,769 | 9,693,788 | 9,647,726 | 9,458,745 | |
| Shares (Diluted) | 93,510,544 | 53,381,989 | -76,793,154 | 51,017,662 | 34,685,072 | 34,685,072 | -61,650,747 | 34,355,050 | 34,318,709 | 25,048,134 | 21,127,281 | 19,048,627 | 17,917,769 | 9,693,788 | 9,647,726 | 9,458,745 |
资产负债表 21
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $48M | $28M | $21M | $32M | $52M | $13M | $13M | $10M | $15M | $66M | $20M | $25M | $17M | $18M | $29M | $36M | |
| Short-term Investments | $139M | $1M | $15M | $16M | $4M | $10M | $22M | $33M | $47M | · | · | · | · | · | · | · | |
| Prepaid Expense | · | · | · | $2M | $2M | $2M | · | $3M | $1M | $1M | $2M | $958.0K | $2M | $3M | $1M | $1M | |
| Current Assets | $188M | $31M | $40M | $50M | $57M | $25M | $36M | $46M | $63M | $68M | $22M | $26M | $18M | $21M | $31M | $38M | |
| PP&E (Net) | · | · | $3.0K | · | · | · | $8.0K | · | · | · | · | · | · | · | · | · | |
| PP&E (Gross) | · | · | $256.0K | · | · | · | $256.0K | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $253.0K | · | · | · | $248.0K | · | · | · | · | · | · | · | · | · | |
| Goodwill | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | |
| Intangibles | $640.0K | $696.0K | $751.0K | $807.0K | $863.0K | $918.0K | $974.0K | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $2M | $2M | |
| Total Assets | $190M | $33M | $42M | $52M | $59M | $27M | $39M | $48M | $65M | $70M | $24M | $29M | $21M | $24M | $34M | $41M | |
| Accounts Payable | · | · | · | $2M | $1M | $2M | · | $1M | $550.0K | $373.0K | $638.0K | $361.0K | $1M | $412.0K | $656.0K | $418.0K | |
| Accrued Liabilities | $200.0K | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Current Liabilities | $198M | $12M | $9M | $10M | $9M | $7M | $7M | $7M | $14M | $21M | $4M | $3M | $20M | $7M | $5M | $4M | |
| Capital Leases | · | · | $5.0K | $21.0K | $37.0K | $52.0K | $66.0K | · | · | · | $22.0K | $38.0K | $54.0K | · | · | · | |
| Total Liabilities | $205M | $22M | $20M | $18M | $17M | $17M | $18M | $17M | $23M | $21M | $20M | $19M | $20M | $23M | $21M | $19M | |
| Common Stock | $170.0K | $121.0K | $121.0K | $121.0K | $118.0K | $103.0K | $103.0K | $103.0K | $103.0K | $103.0K | $90.0K | $90.0K | $87.0K | $79.0K | $79.0K | $79.0K | |
| Retained Earnings | $-345M | $-270M | $-260M | $-246M | $-231M | $-218M | $-206M | $-193M | $-181M | $-172M | $-160M | $-153M | $-145M | $-125M | $-112M | $-101M | |
| AOCI | $-88.0K | $2.0K | $10.0K | $9.0K | $3.0K | $6.0K | $31.0K | $75.0K | $-7.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | |
| Stockholders' Equity | $-15M | $11M | $22M | $34M | $42M | $10M | $21M | $31M | $42M | $49M | $4M | $10M | $443.0K | $1M | $13M | $21M | |
| Liabilities + Equity | $190M | $33M | $42M | $52M | $59M | $27M | $39M | $48M | $65M | $70M | $24M | $29M | $21M | $24M | $34M | $41M | |
| Shares Outstanding | 102,717,200 | 53,240,988 | 53,233,988 | 52,812,488 | 49,685,072 | 34,685,072 | 34,685,072 | 34,389,946 | 34,341,303 | 34,251,911 | 21,165,760 | 21,105,760 | 17,930,362 | 9,710,747 | 9,681,855 | 9,473,577 |
现金流 7
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $58.0K | $57.0K | $57.0K | $54.0K | $55.0K | $62.0K | $58.0K | $57.0K | $57.0K | $57.0K | $58.0K | $55.0K | $58.0K | $55.0K | $56.0K | $60.0K | |
| Stock-based Comp | $7M | $-685.0K | $1M | $2M | $3M | $2M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $829.0K | $840.0K | $823.0K | |
| Amort. of Intangibles | · | $100.0K | $-100.0K | $100.0K | $100.0K | $100.0K | $-100.0K | $100.0K | $100.0K | $100.0K | $100.0K | $100.0K | $100.0K | $100.0K | $100.0K | $100.0K | |
| Operating Cash Flow | $-11M | $-7M | $-18M | $-11M | $-9M | $-11M | $-9M | $-10M | $-5M | $-5M | $-5M | $-7M | $-8M | $-11M | $-8M | $-7M | |
| Investing Cash Flow | $-138M | $14M | $709.0K | $-13M | $7M | $11M | $12M | $13M | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $168M | $21.0K | $6M | $4M | · | · | $682.0K | $-8M | $-153.0K | $56M | $0 | $15M | $47.0K | $146.0K | $1M | $95.0K | |
| Net Change in Cash | $20M | $7M | $-11M | $-20M | $39M | $263.0K | $3M | $-5M | $-52M | $51M | $-5M | $9M | $-8M | $-11M | $-7M | $-7M |
盈利能力 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -60.0% | -33.6% | · | -28.9% | -20.6% | -26.3% | · | -34.6% | -18.1% | -14.3% | -29.6% | -26.2% | -29.3% | -42.5% | -26.3% | -20.4% | |
| ROE | -554.0% | -97.0% | · | -44.4% | -30.3% | -43.0% | · | -70.7% | -32.6% | -26.0% | -279.7% | -72.1% | -82.2% | -73.2% | -38.8% | -29.4% |
流动性与偿付能力 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 1.0 | 2.6 | · | 5.1 | 6.6 | 3.5 | · | 6.8 | 4.6 | 3.3 | 5.4 | 7.7 | 0.9 | 3.0 | 5.8 | 9.4 | |
| Quick Ratio | 0.9 | 2.5 | · | 4.9 | 6.5 | 3.3 | · | 6.4 | 4.5 | 3.2 | 4.9 | 7.3 | 0.8 | 2.6 | 5.5 | 9.1 |
估值 (TTM) 7
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-112M | $-50M | · | $-52M | $-47M | $-40M | · | $-35M | $-30M | $-31M | $-37M | $-41M | $-40M | $-38M | $-32M | $-33M | |
| Market Cap | $671M | $157M | · | $166M | $112M | $93M | · | $163M | $161M | $156M | $91M | $110M | $122M | $32M | $47M | $72M | |
| P/E | -4.0 | -2.4 | · | -2.3 | -1.7 | -2.2 | · | -3.9 | -3.7 | -3.0 | -1.6 | -1.5 | -1.8 | -0.8 | -1.2 | · | |
| P/B | -45.7 | 14.7 | · | 4.9 | 2.7 | 9.0 | · | 5.2 | 3.8 | 3.2 | 22.5 | 11.3 | 275.2 | 30.7 | 3.6 | 3.3 | |
| P / Tangible Book | · | 17.5 | · | 5.2 | 2.8 | 11.1 | · | 5.6 | 4.0 | 3.3 | 51.9 | 14.9 | · | · | 4.5 | 3.8 | |
| P / Cash Flow | · | -22.6 | · | · | · | -8.4 | · | · | · | -29.5 | · | · | -14.7 | · | · | -10.6 | |
| Earnings Yield | -25.1% | -41.2% | · | -43.8% | -59.7% | -46.4% | · | -25.5% | -27.2% | -33.6% | -60.9% | -64.7% | -54.9% | -119.4% | -84.4% | · |
财务报表 损益表、资产负债表、现金流量表 — 年度，近5年
损益表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 净收入 | $-55M | $-40M | $-30M | $-42M | $-33M |
| 稀释后每股收益 (EPS) | $-1.25 | $-1.24 | $-1.50 | $-4.00 | $-4.08 |
资产负债表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 流动比率 | — | 5.5 | 0.8 | — | 9.8 |
| 速动比率 | — | 5.1 | 0.7 | — | 9.5 |
现金流
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 自由现金流 | — | — | $-24M | — | — |
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机构持有人 (13F) 123 家申报者 · $477.1M 总计 · 截至 2026年6月30日
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
机构活动 — Q2 2026 与上一季度对比
| 新仓位 | 已退出持仓 | 增加 | 减少 | 净股数变动 |
|---|---|---|---|---|
| 51 (+32 与上一季度对比) | 17 (+8 与上一季度对比) | 37 (+16 与上一季度对比) | 14 (-8 与上一季度对比) | +52.9M |
与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天，外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过，优先显示最近一个已完整报告的季度对。
| 机构 | 价值 | 股份 | % 已追踪的13F | 类型 |
|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | $49724879 | 7614836 | 10.42% | 股份 |
| TPG GP A, LLC | $44910597 | 6877580 | 9.41% | 股份 |
| venBio Partners LLC | $38623122 | 5914720 | 8.10% | 股份 |
| Logos Global Management LP | $35425250 | 5425000 | 7.43% | 股份 |
| FRANKLIN RESOURCES INC | $32344527 | 4953220 | 6.78% | 股份 |
| Paradigm Biocapital Advisors LP | $32335620 | 4951856 | 6.78% | 股份 |
| VANGUARD CAPITAL MANAGEMENT LLC | $27039502 | 4140812 | 5.67% | 股份 |
| Propel Bio Management, LLC | $26342138 | 4034018 | 5.52% | 股份 |
| STATE STREET CORP | $19234285 | 2945526 | 4.03% | 股份 |
| Vivo Capital, LLC | $17964239 | 2751032 | 3.77% | 股份 |
| Venrock Adviser, LLC | $17964239 | 2751032 | 3.77% | 股份 |
| EVENTIDE ASSET MANAGEMENT, LLC | $14496600 | 2220000 | 3.04% | 股份 |
| Alyeska Investment Group, L.P. | $12574965 | 1925722 | 2.64% | 股份 |
| MARSHALL WACE, LLP | $11778781 | 1803795 | 2.47% | 股份 |
| GEODE CAPITAL MANAGEMENT, LLC | $11492229 | 1759568 | 2.41% | 股份 |
| Simplify Asset Management Inc. | $9351646 | 1432105 | 1.96% | 股份 |
| WELLINGTON MANAGEMENT GROUP LLP | $9090511 | 1392115 | 1.91% | 股份 |
| Caption Management, LLC | $7676015 | 1175500 | 1.61% | 买入期权 |
| LPL Financial LLC | $5891725 | 902255 | 1.23% | 股份 |
| Spruce Street Capital LP | $4810240 | 736637 | 1.01% | 股份 |
| VANGUARD FIDUCIARY TRUST CO | $3877194 | 593751 | 0.81% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3771075 | 577500 | 0.79% | 买入期权 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3510502 | 537596 | 0.74% | 股份 |
| KVP Capital Advisors, LP | $3019178 | 462355 | 0.63% | 股份 |
| TWO SIGMA INVESTMENTS, LP | $2880951 | 441187 | 0.60% | 股份 |
| RAYMOND JAMES FINANCIAL INC | $2741340 | 419807 | 0.57% | 股份 |
| UBS Group AG | $1837555 | 281402 | 0.39% | 股份 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1515861 | 232138 | 0.32% | 股份 |
| Caption Management, LLC | $1487096 | 227733 | 0.31% | 股份 |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1483472 | 227178 | 0.31% | 股份 |
| JANE STREET GROUP, LLC | $1331467 | 203900 | 0.28% | 买入期权 |
| CITADEL ADVISORS LLC | $1326243 | 203100 | 0.28% | 买入期权 |
| RENAISSANCE TECHNOLOGIES LLC | $1162660 | 178049 | 0.24% | 股份 |
| TWO SIGMA ADVISERS, LP | $1043203 | 209900 | 0.22% | 股份 |
| CITADEL ADVISORS LLC | $804032 | 123129 | 0.17% | 股份 |
| CANTOR FITZGERALD, L. P. | $794250 | 121631 | 0.17% | 股份 |
| BNP PARIBAS FINANCIAL MARKETS | $791534 | 121215 | 0.17% | 股份 |
| BANK OF AMERICA CORP /DE/ | $758727 | 116191 | 0.16% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $677161 | 103700 | 0.14% | 卖出期权 |
| WELLS FARGO & COMPANY/MN | $650564 | 99627 | 0.14% | 股份 |
| Shay Capital LLC | $606049 | 92810 | 0.13% | 股份 |
| XTX Topco Ltd | $587896 | 90030 | 0.12% | 股份 |
| RHUMBLINE ADVISERS | $568253 | 87023 | 0.12% | 股份 |
| Blue Trust, Inc. | $560849 | 85888 | 0.12% | 股份 |
| Diametric Capital, LP | $530098 | 81179 | 0.11% | 股份 |
| CITIGROUP INC | $454632 | 69622 | 0.10% | 股份 |
| MANCHESTER FINANCIAL INC | $438666 | 67177 | 0.09% | 股份 |
| MEMBERS WEALTH LLC | $435962 | 66763 | 0.09% | 股份 |
| Virtus Investment Advisers, LLC | $387066 | 59275 | 0.08% | 股份 |
| ADAR1 Capital Management, LLC | $351314 | 53800 | 0.07% | 股份 |
| JANE STREET GROUP, LLC | $329197 | 50413 | 0.07% | 股份 |
| MetLife Investment Management, LLC | $300282 | 45985 | 0.06% | 股份 |
| OSAIC HOLDINGS, INC. | $281540 | 43115 | 0.06% | 股份 |
| WINTON GROUP Ltd | $277525 | 42500 | 0.06% | 股份 |
| GOLDMAN SACHS GROUP INC | $267573 | 40976 | 0.06% | 股份 |
| Bank of New York Mellon Corp | $261559 | 40055 | 0.05% | 股份 |
| Rafferty Asset Management, LLC | $245012 | 37521 | 0.05% | 股份 |
| BlackRock, Inc. | $235015 | 35990 | 0.05% | 股份 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $233062 | 35691 | 0.05% | 股份 |
| Next Capital Management LLC | $228517 | 34995 | 0.05% | 股份 |
| AMERIFLEX GROUP, INC. | $219395 | 33598 | 0.05% | 股份 |
| Vanguard Global Advisers, LLC | $211624 | 32408 | 0.04% | 股份 |
| Invesco Ltd. | $202691 | 31040 | 0.04% | 股份 |
| JPMORGAN CHASE & CO | $201042 | 32270 | 0.04% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $198329 | 30372 | 0.04% | 股份 |
| Rockefeller Capital Management L.P. | $195900 | 30000 | 0.04% | 股份 |
| Jones Hill Capital LP | $174743 | 26760 | 0.04% | 股份 |
| BCV Asset Management Inc. | $164591 | 26365 | 0.03% | 股份 |
| AXQ CAPITAL, LP | $164380 | 25173 | 0.03% | 股份 |
| Nuveen Asset Management, LLC | $164271 | 46668 | 0.03% | 股份 |
| Robertson Stephens Wealth Management, LLC | $163250 | 25000 | 0.03% | 股份 |
| Keating Financial Advisory Services, Inc. | $162669 | 24911 | 0.03% | 股份 |
| Police & Firemen's Retirement System of New Jersey | $149916 | 22958 | 0.03% | 股份 |
| ALLIANCEBERNSTEIN L.P. | $143884 | 48940 | 0.03% | 股份 |
| Scientech Research LLC | $143706 | 22007 | 0.03% | 股份 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $134583 | 20610 | 0.03% | 股份 |
| SEI INVESTMENTS CO | $133865 | 20500 | 0.03% | 股份 |
| Nuveen, LLC | $133865 | 20500 | 0.03% | 股份 |
| PROFUND ADVISORS LLC | $129660 | 19856 | 0.03% | 股份 |
| NEW YORK STATE COMMON RETIREMENT FUND | $125376 | 19200 | 0.03% | 股份 |
| nVerses Capital, LLC | $118852 | 18201 | 0.02% | 股份 |
| VANGUARD GROUP INC | $112337 | 22603 | 0.02% | 股份 |
| Cubist Systematic Strategies, LLC | $111898 | 35523 | 0.02% | 股份 |
| MAGNOLIA CAPITAL ADVISORS LLC | $98603 | 15100 | 0.02% | 股份 |
| VOYA INVESTMENT MANAGEMENT LLC | $96931 | 14844 | 0.02% | 股份 |
| SBI Securities Co., Ltd. | $96912 | 14841 | 0.02% | 股份 |
| INTECH INVESTMENT MANAGEMENT LLC | $89696 | 13736 | 0.02% | 股份 |
| StoneX Group Inc. | $86507 | 16342 | 0.02% | 股份 |
| PRUDENTIAL FINANCIAL INC | $85151 | 13040 | 0.02% | 股份 |
| Alpine Global Management, LLC | $81625 | 12500 | 0.02% | 股份 |
| NORTHERN TRUST CORP | $79790 | 12219 | 0.02% | 股份 |
| Windsor Capital Management, LLC | $70635 | 10817 | 0.01% | 股份 |
| BARCLAYS PLC | $66861 | 10239 | 0.01% | 股份 |
| ProShare Advisors LLC | $66554 | 10192 | 0.01% | 股份 |
| Legal & General Group Plc | $49334 | 7555 | 0.01% | 股份 |
| Ameritas Investment Partners, Inc. | $46128 | 7064 | 0.01% | 股份 |
| FMR LLC | $41211 | 6311 | 0.01% | 股份 |
| Russell Investments Group, Ltd. | $40642 | 6224 | 0.01% | 股份 |
| Point72 Asia (Singapore) Pte. Ltd. | $23641 | 7505 | 0.00% | 股份 |
| Allworth Financial LP | $19590 | 3000 | 0.00% | 股份 |
公司内部人士 48 位内幕人士 · 17 位高管 · 26 位董事
| 内部人士 | 角色 | 上次活动 | 持股数量 | 买入 12个月 | 卖出 12个月 | 净额 12个月 |
|---|---|---|---|---|---|---|
| Andrew D. Goldberg | CEO and President | 2026年4月18日 A | — | 0 | 0 | $0 |
| John Bencich | CEO | 2024年8月16日 A | 100636 | 0 | 0 | $0 |
| Mark K Oki | Chief Financial Officer | 2026年1月28日 A | 127940 | 0 | 1 | $-146175 |
| Michelle Renee Griffin | CFO | 2012年5月8日 A | — | 0 | 0 | $0 |
| Stephen Charles Anderson | CFO and Secretary | 2009年12月31日 A | 10000 | 0 | 0 | $0 |
| Alan Fuhrman | Senior Vice President & CFO | 2008年3月18日 A | — | 0 | 0 | $0 |
| Cindy Jacobs | President & CMO | 2025年9月4日 M | 115585 | 0 | 1 | $-76532 |
| Mark Lawrence Rubinstein | Chief Medical Officer | 2026年1月28日 A | — | 0 | 0 | $0 |
| Craig Donnelly | Chief Operations Officer | 2026年1月28日 A | — | 0 | 0 | $0 |
| Jaime Xinos | Chief Commercial Officer | 2026年1月28日 A | 74432 | 0 | 1 | $-57766 |
| Jerry Wann | Principal Accounting Officer | 2026年1月28日 A | 32694 | 0 | 1 | $-38974 |
| Erik Atkisson | Chief Legal Officer | 2025年12月4日 A | — | 0 | 0 | $0 |
| Anthony Clarke | CSO | 2022年4月28日 M | 3502 | 0 | 0 | $0 |
| Susan D. Wyrick | PAO | 2014年3月14日 A | 1312 | 0 | 0 | $0 |
| Cameron William Lawrence | Principal Accounting Officer | 2012年5月8日 A | 950 | 0 | 0 | $0 |
| Craig Steven Eudy | Principal Accounting Officer | 2006年12月29日 A | — | 0 | 0 | $0 |
| Michael B Stewart | Sr. VP & Chief Medical Officer | 2005年12月16日 A | — | 0 | 0 | $0 |
| Reid Alexander Waldman | 董事 | 2026年7月27日 A | — | 0 | 0 | $0 |
| Christopher Nathan Martin | 董事 | 2026年7月27日 A | — | 0 | 0 | $0 |
| Thomas Sellig | 董事 | 2026年7月27日 A | — | 0 | 0 | $0 |
| Nancy R. Phelan | 董事 | 2026年7月27日 A | — | 0 | 0 | $0 |
| Aaron Royston | 董事 | 2026年7月27日 A | — | 0 | 0 | $0 |
| Richard Alistair Stewart | 董事 | 2026年7月27日 A | 228875 | 0 | 1 | $-378143 |
| Jeffrey S Farrow | 董事 | 2026年7月27日 A | — | 0 | 0 | $0 |
| Thomas Braxton King | 董事 | 2025年9月4日 M | 315142 | 0 | 1 | $-387407 |
| Kristen B. Slaoui | 董事 | 2025年6月6日 A | — | 0 | 0 | $0 |
| Stuart Duty | 董事 | 2025年6月6日 A | — | 0 | 0 | $0 |
| Bridget A Martell | 董事 | 2025年6月6日 A | — | 0 | 0 | $0 |
| Vaughn B Himes | 董事 | 2024年1月22日 A | — | 0 | 0 | $0 |
| Donald Joseph | 董事 | 2022年5月31日 A | — | 0 | 0 | $0 |
| Martin A Mattingly | 董事 | 2022年5月31日 A | 10500 | 0 | 0 | $0 |
| Jay M Moyes | 董事 | 2022年5月31日 A | — | 0 | 0 | $0 |
| Scott Daniel Cormack | 董事 | 2020年5月12日 A | 14810 | 0 | 0 | $0 |
| PARKER H STEWART | 董事 | 2020年5月12日 A | 12500 | 0 | 0 | $0 |
| Neil James Clendeninn | 董事 | 2016年5月26日 A | 22421 | 0 | 0 | $0 |
| Jack Goldstein | 董事 | 2016年5月26日 A | 17500 | 0 | 0 | $0 |
| David V Smith | 董事 | 2016年5月26日 A | 9500 | 0 | 0 | $0 |
| Dwight Winstead | 董事 | 2010年5月17日 M | 0 | 0 | 0 | $0 |
| Patrick Robert Brady | 董事 | 2009年5月12日 A | — | 0 | 0 | $0 |
| Robert E Ivy | 董事 | 2007年5月18日 M | 1700 | 0 | 0 | $0 |
| George W Dunbar JR | 董事 | 2007年5月10日 A | 3250 | 0 | 0 | $0 |
| VENTURES WEST CAPITAL LTD | 10% 所有者 | 2008年12月15日 S | 41763 | 0 | 0 | $0 |
| SAC CAPITAL ADVISORS LLC | 10% 所有者 | 2004年2月19日 P | 1419752 | 0 | 0 | $0 |
| SAC CAPITAL ASSOCIATES LLC | 10% 所有者 | 2004年2月19日 P | 867376 | 0 | 0 | $0 |
| S A C CAPITAL MANAGEMENT L L C | 10% 所有者 | 2004年2月19日 P | 1419752 | 0 | 0 | $0 |
| Steven A. Cohen | 10% 所有者 | 2004年2月19日 P | 1419752 | 0 | 0 | $0 |
| Michael A Martino | — | 2010年7月6日 M | 11000 | 0 | 0 | $0 |
| Richard J Klein | — | 2003年12月29日 A | — | 0 | 0 | $0 |
来自SEC表格3/4/5申报的内部人士；净额=仅公开市场买卖
激进投资者及 5%+ 股东 9 持仓
提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权，意图影响发行人（激进股东持股、董事会活动、并购）。每一行显示该申报人持仓的最新已知状态。
| 申报人 | 已申报 | 持股 | 状态 | 目的 | 申报 |
|---|---|---|---|---|---|
| venBio Global Strategic Fund V, L.P., venBio Global Strategic GP V, LLC | 2026年4月27日 | 9.99% | 初始申报 | 被动投资 | SEC |
| TPG GP A, LLC, James G. Coulter, Jon Winkelried | 2026年4月24日 | 12.60% | 初始申报 | 董事会活动 | SEC |
| Dialectic Capital Management, LP, Dialectic Partners, LLC, Dialectic Life Sciences SPV LLC, Dialectic LS Manager LLC, John Fichthorn ×3 申报 | 2023年3月23日 | — | 初始申报 | — | SEC |
| Anthony Clarke | 2017年8月11日 | — | 初始申报 | 被动投资 | SEC |
| Richard Stewart | 2017年8月11日 | — | 初始申报 | 被动投资 | SEC |
| Working Opportunity Fund (EVCC) Ltd., GrowthWorks Capital Ltd. ×5 申报 | 2011年2月14日 | — | 初始申报 | — | SEC |
| 2010年10月28日 | — | 初始申报 | — | SEC | |
| Abingworth LLP | 2010年8月20日 | — | 初始申报 | 被动投资 | SEC |
| SCHERING BERLIN VENTURE CORPORATION, SCHERING BERLIN INC., SCHERING INTERNATIONAL HOLDING GmbH, SCHERING AKTIENGESELLSCHAFT | 2005年10月31日 | — | 初始申报 | 被动投资 | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF持仓 由 9 只交易所交易基金持有
权重仅反映直接股权持仓（N-PORT）；杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。
| 基金 | 权重 | 单位 | 截至 | 来源 |
|---|---|---|---|---|
| VXF · VANGUARD INDEX FUNDS | — | — | 2026年7月15日 | 每日 |
| VTI · VANGUARD INDEX FUNDS | — | — | 2026年7月15日 | 每日 |
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | 2026年7月15日 | 每日 |
| VTWG · VANGUARD SCOTTSDALE FUNDS | — | — | 2026年7月15日 | 每日 |
| VTHR · VANGUARD SCOTTSDALE FUNDS | — | — | 2026年7月15日 | 每日 |
| IWV · iShares Trust | — | — | 2026年8月18日 | 每日 |
| IWO · iShares Trust | — | — | 2026年8月18日 | 每日 |
| IWM · iShares Trust | — | — | 2026年8月18日 | 每日 |
| IWC · iShares Trust | — | — | 2026年8月18日 | 每日 |