ANNX Annexon, Inc. - common stock
$5.54
价格 · 八月 19, 2026
截至...的财报数据 八月 12, 2026
52周区间
$2–$7
68% of range
分析师评级
BUY
17 analysts
目标价
$15
+166% upside
P/E (TTM)
-4.1
ROE
-100.7%
净利润率
—
ANNX 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围
价格
$5.54
市值
$827M
P/E (TTM)
-4.1
每股收益 (TTM)
$-1.34
营收 (TTM)
—
股息收益率
—
ROE
-100.7%
负债/权益
—
52周区间
$2 – $7
ANNX 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图
Configure
10年表现 收入、净利润、利润率和每股收益趋势
营收与净利润
—
EPS
$-1.34
2021-12-31
→
2025-12-31
自由现金流
$-186M
2020-12-31
→
2025-12-31
利润率
—
估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜？
指标
5年趋势
ANNX
同行中位数
P/E (TTM)
-4.1
—
P/B (市净率)
3.9
3.4
Price / FCF (股价/自由现金流)
-4.4
—
盈利能力 毛利率、营业利润率和净利率；股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)
指标
5年趋势
ANNX
同行中位数
ROA
-65.9%
-31.3%
ROE
-100.7%
-38.1%
ROIC
-102.2%
—
财务健康 债务、流动性、偿付能力 — 资产负债表强度
指标
5年趋势
ANNX
同行中位数
Current Ratio (流动比率)
5.7
10.9
Quick Ratio (速动比率)
3.8
—
成长 营收、每股收益 (EPS) 和净利润增长：同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)
指标
5年趋势
ANNX
同行中位数
资本效率 资产周转率、库存周转率、应收账款周转率
指标
5年趋势
ANNX
同行中位数
ANNX 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间
买入
17 位分析师
- 强烈买入 4 23.5%
- 买入 10 58.8%
- 持有 2 11.8%
- 卖出 1 5.9%
- 强烈卖出 0 0.0%
12个月价格目标
7 位分析师 · 2026-08-17
中位数
$12.00
平均值
$14.71
← 低于所有目标
$5.54
最低
$7.00
最高
$27.00
中位数目标
$12.00
+116.8%
平均目标
$14.71
+165.8%
收益历史 每股收益实际值 vs 预估值，惊喜%，达标率，下次财报日期
平均惊喜
-0.00%
| 期间 | EPS Actual | EPS 预期 | 惊喜 |
|---|---|---|---|
| 2026年3月31日 | $-0.23 | $-0.29 | 0.06% |
| 2025年12月31日 | $-0.28 | $-0.32 | 0.04% |
| 2025年9月30日 | $-0.37 | $-0.35 | -0.02% |
| 2025年6月30日 | $-0.34 | $-0.37 | 0.03% |
| 2025年3月31日 | $-0.37 | $-0.30 | -0.07% |
| 2024年12月31日 | $-0.33 | $-0.27 | -0.06% |
同行比较（GICS 子行业） 关键指标与行业同行对比
| 股票代码 | 市值 | P/E | 营收同比增长 | 净利润率 | ROE | 毛利率 |
|---|---|---|---|---|---|---|
| ANNX | $750M | -3.7 | — | — | -100.7% | — |
| SVRA | $1.23B | -11.4 | — | — | -73.4% | — |
| KURA | $913M | -3.3 | 25.2% | -413.0% | -116.2% | — |
| AVTX | $336M | -3.1 | -86.6% | -132642.4% | -83.4% | — |
| JANX | $833M | -7.5 | -5.5% | -1136.2% | -11.7% | — |
| SLDB | $445M | -2.8 | — | — | -79.5% | — |
| GERN | $845M | -10.2 | -60.2% | — | -34.4% | — |
| ARDX | $1.42B | -22.4 | 22.1% | -15.1% | -40.2% | — |
| CADL | $310M | -7.8 | — | — | -53.7% | — |
| DSGN | $567M | -7.7 | — | — | -32.8% | — |
完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表
损益表 13
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| R&D Expense | $185M | $119M | $114M | $113M | $100M | $49M | $25M | |
| SG&A Expense | $32M | $35M | $30M | $33M | $31M | $14M | $8M | |
| Operating Expenses | $216M | $154M | $144M | $146M | $131M | $63M | $33M | |
| Operating Income | $-216M | $-154M | $-144M | $-146M | $-131M | $-63M | $-33M | |
| Other Non-op | · | · | · | · | · | $57.0K | $1M | |
| Pretax Income | $-207M | $-138M | $134M | $142M | $130M | $-63M | $-37M | |
| Income Tax | $0 | $0 | $0 | $0 | · | · | $4.0K | |
| Net Income | $-207M | $-138M | $-134M | $-142M | $-130M | $-63M | $-37M | |
| EPS (Basic) | $-1.34 | $-1.01 | $-1.77 | $-2.60 | $-3.40 | · | · | |
| EPS (Diluted) | $-1.34 | $-1.01 | $-1.77 | $-2.60 | $-3.40 | · | · | |
| Shares (Basic) | 155,105,832 | 137,404,145 | 75,673,081 | 54,673,572 | 38,316,273 | · | · | |
| Shares (Diluted) | 155,105,832 | 137,404,145 | 75,673,081 | 54,673,572 | 38,316,273 | · | · | |
| EBITDA | $-214M | $-152M | $-142M | $-143M | $-129M | $-63M | · |
资产负债表 21
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $162M | $49M | $225M | $140M | $75M | $269M | $44M | |
| Prepaid Expense | $4M | $4M | $4M | $5M | $5M | $3M | $1M | |
| Other Current Assets | · | · | $63.0K | $203.0K | $463.0K | $3.0K | $79.0K | |
| Current Assets | $242M | $316M | $264M | $248M | $248M | $354M | $45M | |
| PP&E (Net) | $11M | $13M | $15M | $17M | $18M | $2M | $2M | |
| PP&E (Gross) | $20M | $20M | $20M | $20M | $19M | $4M | $3M | |
| Accum. Depreciation | $9M | $7M | $5M | $3M | $789.0K | $2M | $1M | |
| Other Non-current Assets | $9M | $3M | · | · | · | · | $2M | |
| Total Assets | $278M | $350M | $298M | $285M | $287M | $356M | $50M | |
| Accounts Payable | $15M | $10M | $5M | $7M | $11M | $4M | $2M | |
| Accrued Liabilities | · | · | $10M | $13M | $9M | $6M | $2M | |
| Current Liabilities | $43M | $31M | $18M | $22M | $22M | $11M | $5M | |
| Capital Leases | $23M | $26M | $29M | $32M | $33M | · | · | |
| Total Liabilities | $66M | $57M | $47M | $54M | $55M | $12M | $6M | |
| Common Stock | $149.0K | $109.0K | $78.0K | $48.0K | $39.0K | $38.0K | $4.0K | |
| Paid-in Capital | $1.13B | $1.00B | $823M | $670M | $528M | $510M | $2M | |
| Retained Earnings | $-917M | $-711M | $-572M | $-438M | $-296M | $-166M | $-103M | |
| AOCI | $-29.0K | $10.0K | $-52.0K | $-372.0K | $-180.0K | $-77.0K | $-80.0K | |
| Stockholders' Equity | $212M | $293M | $251M | $231M | $232M | $344M | $-100M | |
| Liabilities + Equity | $278M | $350M | $298M | $285M | $287M | $356M | $50M | |
| Shares Outstanding | 149,362,800 | 109,381,556 | 78,369,099 | 47,722,995 | 38,560,854 | 38,157,618 | 433,749 |
现金流 10
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| D&A | $2M | $2M | $2M | $2M | $2M | $667.0K | $493.0K | |
| Stock-based Comp | $16M | $19M | $18M | $19M | $16M | $5M | $2M | |
| Other Non-cash | $2M | $-1M | $-7M | $5M | $6M | $5M | · | |
| Operating Cash Flow | $-186M | $-118M | $-121M | $-116M | $-106M | $-53M | $-28M | |
| CapEx | $137.0K | $15.0K | $193.0K | $7M | $2M | $464.0K | $267.0K | |
| Investing Cash Flow | $190M | $-219M | $71M | $58M | $-88M | $-83M | $-267.0K | |
| Stock Issued | $28M | $44M | $18M | · | · | · | · | |
| Net Stock Activity | $28M | $44M | · | · | · | · | · | |
| Financing Cash Flow | $109M | $161M | $136M | $123M | $2M | $361M | $28M | |
| Free Cash Flow | $-186M | $-118M | $-121M | $-123M | $-108M | $-54M | · |
盈利能力 3
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -65.9% | -42.7% | -46.1% | -49.6% | -40.5% | -31.2% | · | |
| ROE | -100.7% | -44.2% | -65.9% | -57.7% | -52.5% | -17.9% | · | |
| ROIC | -102.2% | -52.6% | -57.4% | · | · | · | · |
流动性与偿付能力 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 5.7 | 10.4 | 14.7 | 11.1 | 11.4 | 33.3 | · | |
| Quick Ratio | 3.8 | 1.6 | 12.6 | 6.3 | 3.4 | 25.3 | · |
估值 (TTM) 8
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-207M | $-138M | $-134M | $-142M | $-130M | $-63M | · | |
| Market Cap | $750M | $561M | $356M | $247M | $443M | $955M | · | |
| P/E | -3.7 | -5.1 | -2.6 | -2.0 | -3.4 | · | · | |
| P/B | 3.5 | 1.9 | 1.4 | 1.1 | 1.9 | 2.8 | · | |
| P / Tangible Book | 3.5 | 1.9 | 1.4 | 1.1 | 1.9 | 2.8 | · | |
| P / Cash Flow | -4.0 | -4.8 | -2.9 | -2.1 | -4.2 | -18.0 | · | |
| P / FCF | -4.0 | -4.8 | -2.9 | -2.0 | -4.1 | -17.8 | · | |
| Earnings Yield | -26.7% | -19.7% | -39.0% | -50.3% | -29.6% | · | · |
损益表 10
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $47M | $36M | $43M | $50M | $44M | $48M | $43M | $30M | $25M | $21M | $23M | $28M | $30M | $32M | $29M | $28M | |
| SG&A Expense | $11M | $10M | $8M | $7M | $8M | $9M | $9M | $9M | $9M | $8M | $7M | $7M | $7M | $9M | $8M | $8M | |
| Operating Expenses | $57M | $46M | $50M | $57M | $52M | $57M | $52M | $39M | $34M | $29M | $30M | $35M | $38M | $41M | $37M | $36M | |
| Operating Income | $-57M | $-46M | $-50M | $-57M | $-52M | $-57M | $-52M | $-39M | $-34M | $-29M | $-30M | $-35M | $-38M | $-41M | $-37M | $-36M | |
| Net Income | $-55M | $-44M | $-48M | $-55M | $-49M | $-54M | $-49M | $-35M | $-30M | $-25M | $-28M | $-32M | $-35M | $-39M | $-34M | $-35M | |
| EPS (Basic) | $-0.28 | $-0.23 | $-0.26 | $-0.37 | $-0.34 | $-0.37 | $-0.32 | $-0.25 | $-0.23 | $-0.21 | $-0.35 | $-0.43 | $-0.47 | $-0.52 | $-0.21 | $-0.51 | |
| EPS (Diluted) | $-0.28 | $-0.23 | $-0.26 | $-0.37 | $-0.34 | $-0.37 | $-0.32 | $-0.25 | $-0.23 | $-0.21 | $-0.35 | $-0.43 | $-0.47 | $-0.52 | $-0.21 | $-0.51 | |
| Shares (Basic) | 201,003,269 | 194,200,100 | -290,447,481 | 149,123,701 | 148,320,803 | 148,108,809 | -255,335,036 | 139,933,019 | 130,132,960 | 122,673,202 | -148,755,059 | 75,342,495 | 75,230,003 | 73,855,642 | -91,127,071 | 68,652,859 | |
| Shares (Diluted) | 201,003,269 | 194,200,100 | -290,447,481 | 149,123,701 | 148,320,803 | 148,108,809 | -255,335,036 | 139,933,019 | 130,132,960 | 122,673,202 | -148,755,059 | 75,342,495 | 75,230,003 | 73,855,642 | -91,127,071 | 68,652,859 | |
| EBITDA | $-57M | $-46M | · | $-57M | $-52M | $-57M | · | $-39M | $-34M | $-28M | · | $-35M | $-38M | $-41M | · | $-36M |
资产负债表 21
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $199M | $175M | $162M | $139M | $132M | $97M | $49M | $80M | $157M | $152M | $225M | $133M | $114M | $144M | $140M | $211M | |
| Prepaid Expense | $4M | $3M | $4M | $4M | $4M | $4M | $4M | $4M | $5M | $6M | $4M | $4M | $5M | $4M | $5M | $5M | |
| Other Current Assets | · | · | · | · | · | · | · | · | · | $23.0K | · | $13.0K | $167.0K | $165.0K | $203.0K | $57.0K | |
| Current Assets | $213M | $228M | $242M | $193M | $231M | $268M | $316M | $344M | $374M | $271M | $264M | $169M | $198M | $233M | $248M | $275M | |
| PP&E (Net) | $10M | $10M | $11M | $11M | $12M | $12M | $13M | $13M | $14M | $14M | $15M | $15M | $16M | $16M | $17M | $17M | |
| PP&E (Gross) | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $19M | |
| Accum. Depreciation | $10M | $10M | $9M | $9M | $8M | $8M | $7M | $7M | $6M | $6M | $5M | $4M | $4M | $3M | $3M | $2M | |
| Other Non-current Assets | $8M | $9M | $9M | $9M | $5M | $5M | $3M | $3M | · | $361.0K | · | · | · | $12.0K | · | $204.0K | |
| Total Assets | $246M | $263M | $278M | $229M | $265M | $303M | $350M | $379M | $406M | $304M | $298M | $204M | $233M | $269M | $285M | $313M | |
| Accounts Payable | $16M | $18M | $15M | $18M | $12M | $10M | $10M | $7M | $4M | $4M | $5M | $5M | $7M | $10M | $7M | $7M | |
| Accrued Liabilities | · | · | · | · | · | · | · | · | $11M | $7M | · | $10M | $9M | $11M | $13M | $11M | |
| Current Liabilities | $38M | $36M | $43M | $44M | $41M | $34M | $31M | $20M | $17M | $13M | $18M | $17M | $18M | $23M | $22M | $20M | |
| Capital Leases | $22M | $22M | $23M | $24M | $25M | $26M | $26M | $27M | $28M | $29M | $29M | $30M | $30M | $31M | $32M | $32M | |
| Total Liabilities | $60M | $58M | $66M | $68M | $66M | $59M | $57M | $47M | $45M | $42M | $47M | $47M | $48M | $54M | $54M | $52M | |
| Common Stock | $175.0K | $162.0K | $149.0K | $115.0K | $110.0K | $109.0K | $109.0K | $106.0K | $106.0K | $90.0K | $78.0K | $53.0K | $53.0K | $53.0K | $48.0K | $48.0K | |
| Paid-in Capital | $1.20B | $1.17B | $1.13B | $1.03B | $1.01B | $1.01B | $1.00B | $993M | $988M | $860M | $823M | $702M | $697M | $692M | $670M | $665M | |
| Retained Earnings | $-1.02B | $-962M | $-917M | $-869M | $-814M | $-765M | $-711M | $-662M | $-627M | $-598M | $-572M | $-545M | $-512M | $-477M | $-438M | $-404M | |
| AOCI | $-82.0K | $-81.0K | $-29.0K | $-76.0K | $-93.0K | $-91.0K | $10.0K | $77.0K | $-89.0K | $-102.0K | $-52.0K | $-123.0K | $-171.0K | $-217.0K | $-372.0K | $-406.0K | |
| Stockholders' Equity | $186M | $205M | $212M | $161M | $199M | $244M | $293M | $332M | $361M | $262M | $251M | $157M | $185M | $215M | $231M | $261M | |
| Liabilities + Equity | $246M | $263M | $278M | $229M | $265M | $303M | $350M | $379M | $406M | $304M | $298M | $204M | $233M | $269M | $285M | $313M | |
| Shares Outstanding | · | · | 149,362,800 | · | · | · | 109,381,556 | · | · | · | 78,369,099 | · | · | · | 47,722,995 | · |
现金流 10
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $540.0K | $539.0K | $543.0K | $546.0K | $540.0K | $537.0K | $537.0K | $538.0K | $537.0K | $538.0K | $538.0K | $538.0K | $536.0K | $536.0K | $530.0K | $518.0K | |
| Stock-based Comp | $5M | $4M | $3M | $4M | $4M | $5M | $5M | $5M | $5M | $5M | $4M | $5M | $5M | $5M | $5M | $5M | |
| Other Non-cash | · | $-7M | · | · | · | $-1M | · | · | · | $-8M | · | · | · | $540.0K | · | · | |
| Operating Cash Flow | $-48M | $-47M | $-46M | $-52M | $-38M | $-50M | $-36M | $-32M | $-22M | $-28M | $-23M | $-28M | $-36M | $-33M | $-27M | $-31M | |
| CapEx | $137.0K | $0 | $0 | $48.0K | $15.0K | $74.0K | $6.0K | · | · | · | $7.0K | $19.0K | $30.0K | $137.0K | $282.0K | $169.0K | |
| Investing Cash Flow | $40M | $27M | $-27M | $46M | $73M | $98M | $1M | $-46M | $-97M | $-77M | $-2M | $48M | $6M | $20M | $-44M | $14M | |
| Stock Issued | $32M | $34M | $14M | $14M | $0 | $0 | $5M | $0 | $7M | $33M | $0 | $450.0K | $450.0K | $18M | · | · | |
| Net Stock Activity | · | $34M | · | · | · | · | · | · | · | $33M | · | · | · | $18M | · | · | |
| Financing Cash Flow | $32M | $33M | $95M | $14M | $153.0K | $59.0K | $5M | $175.0K | $124M | $32M | $118M | $0 | $345.0K | $18M | $108.0K | $123M | |
| Free Cash Flow | · | $-47M | · | · | · | $-50M | · | · | · | · | · | · | · | $-33M | · | · |
盈利能力 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -21.7% | -15.6% | · | -18.1% | -14.7% | -17.9% | · | -11.9% | -9.3% | -9.1% | · | -13.8% | -15.5% | · | · | -11.3% | |
| ROE | -28.7% | -19.7% | · | -22.3% | -17.5% | -21.5% | · | -14.3% | -10.8% | -10.9% | · | -17.5% | -20.0% | · | · | -13.4% |
流动性与偿付能力 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 5.5 | 6.4 | · | 4.4 | 5.7 | 8.0 | · | 17.2 | 21.8 | 20.6 | · | 9.9 | 11.0 | · | · | 13.6 | |
| Quick Ratio | 5.2 | 4.9 | · | 3.2 | 3.3 | 2.9 | · | 4.0 | 9.2 | 11.6 | · | 7.8 | 6.4 | · | · | 10.4 |
估值 (TTM) 3
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-204M | $-203M | · | $-193M | $-168M | $-144M | · | $-122M | $-122M | $-132M | · | $-141M | $-146M | $-146M | · | $-143M | |
| P/E | -4.7 | -4.2 | · | -2.3 | -2.0 | -1.8 | · | -5.3 | -3.7 | -4.4 | · | -1.2 | -1.4 | -1.3 | · | -1.9 | |
| Earnings Yield | -21.4% | -23.6% | · | -43.6% | -49.6% | -54.9% | · | -18.9% | -27.4% | -22.7% | · | -81.8% | -69.9% | -75.6% | · | -53.7% |
财务报表 损益表、资产负债表、现金流量表 — 年度，近5年
损益表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 净收入 | $-207M | $-138M | $-134M | $-142M | $-130M |
| 稀释后每股收益 (EPS) | $-1.34 | $-1.01 | $-1.77 | $-2.60 | $-3.40 |
资产负债表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 流动比率 | 5.7 | 10.4 | 14.7 | 11.1 | 11.4 |
| 速动比率 | 3.8 | 1.6 | 12.6 | 6.3 | 3.4 |
现金流
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 自由现金流 | $-186M | $-118M | $-121M | $-123M | $-108M |
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机构持有人 (13F) 232 家申报者 · $903.9M 总计 · 截至 2026年6月30日
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
机构活动 — Q2 2026 与上一季度对比
| 新仓位 | 已退出持仓 | 增加 | 减少 | 净股数变动 |
|---|---|---|---|---|
| 39 (-29 与上一季度对比) | 26 (+11 与上一季度对比) | 85 (+4 与上一季度对比) | 69 (+14 与上一季度对比) | +25.4M |
与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天，外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过，优先显示最近一个已完整报告的季度对。
| 机构 | 价值 | 股份 | % 已追踪的13F | 类型 |
|---|---|---|---|---|
| FMR LLC | $103712963 | 18163391 | 11.47% | 股份 |
| Redmile Group, LLC | $67776998 | 11869877 | 7.50% | 股份 |
| STATE STREET CORP | $56096873 | 9824321 | 6.21% | 股份 |
| BVF INC/IL | $49666568 | 8698173 | 5.49% | 股份 |
| Woodline Partners LP | $39542133 | 6925067 | 4.37% | 股份 |
| VANGUARD CAPITAL MANAGEMENT LLC | $39233496 | 6871015 | 4.34% | 股份 |
| SATTER MANAGEMENT CO., L.P. | $37992903 | 7406024 | 4.20% | 股份 |
| VANGUARD GROUP INC | $34414053 | 6855389 | 3.81% | 股份 |
| MAK CAPITAL ONE LLC | $33473048 | 5862180 | 3.70% | 股份 |
| Siren, L.L.C. | $25458869 | 4458646 | 2.82% | 股份 |
| Bain Capital Life Sciences Investors, LLC | $25339444 | 4437731 | 2.80% | 股份 |
| Bellevue Group AG | $23411091 | 4100016 | 2.59% | 股份 |
| MPM BIOIMPACT LLC | $20238261 | 3544354 | 2.24% | 股份 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $19985000 | 3500000 | 2.21% | 股份 |
| GREAT POINT PARTNERS LLC | $19985000 | 3500000 | 2.21% | 股份 |
| GEODE CAPITAL MANAGEMENT, LLC | $19758078 | 3459611 | 2.19% | 股份 |
| AMERIPRISE FINANCIAL INC | $19595144 | 3431724 | 2.17% | 股份 |
| GOLDMAN SACHS GROUP INC | $17924655 | 3139169 | 1.98% | 股份 |
| Palo Alto Investors LP | $16833594 | 2948090 | 1.86% | 股份 |
| Balyasny Asset Management L.P. | $16164873 | 2830976 | 1.79% | 股份 |
| Qube Research & Technologies Ltd | $15702277 | 2749961 | 1.74% | 股份 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $12829228 | 2246800 | 1.42% | 股份 |
| Opaleye Management Inc. | $9789515 | 1714451 | 1.08% | 股份 |
| Logos Global Management LP | $8565000 | 1500000 | 0.95% | 股份 |
| DIMENSIONAL FUND ADVISORS LP | $8139776 | 1425530 | 0.90% | 股份 |
| Point72 Asset Management, L.P. | $7895211 | 1382699 | 0.87% | 股份 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7182032 | 1257799 | 0.79% | 股份 |
| Tetragon Partners GP Ltd | $7094418 | 1242455 | 0.78% | 股份 |
| Candriam S.C.A. | $6817695 | 1195142 | 0.75% | 股份 |
| MILLENNIUM MANAGEMENT LLC | $6765956 | 1184931 | 0.75% | 股份 |
| VANGUARD FIDUCIARY TRUST CO | $6312120 | 1105450 | 0.70% | 股份 |
| PANAGORA ASSET MANAGEMENT INC | $5526857 | 967926 | 0.61% | 股份 |
| KENNEDY CAPITAL MANAGEMENT LLC | $5129830 | 898394 | 0.57% | 股份 |
| Ishara Investments LP | $4682200 | 820000 | 0.52% | 股份 |
| Ensign Peak Advisors, Inc | $4570946 | 800516 | 0.51% | 股份 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $4213609 | 737935 | 0.47% | 股份 |
| Y-Intercept (Hong Kong) Ltd | $4194480 | 734585 | 0.46% | 股份 |
| Parkman Healthcare Partners LLC | $3660276 | 641029 | 0.40% | 股份 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $3334143 | 583913 | 0.37% | 股份 |
| SIRIOS CAPITAL MANAGEMENT L P | $3250566 | 569276 | 0.36% | 股份 |
| Schonfeld Strategic Advisors LLC | $3046666 | 533567 | 0.34% | 股份 |
| TWO SIGMA INVESTMENTS, LP | $2928065 | 512796 | 0.32% | 股份 |
| Board of Trustees of The Leland Stanford Junior University | $2755360 | 482550 | 0.30% | 股份 |
| RENAISSANCE TECHNOLOGIES LLC | $2620890 | 459000 | 0.29% | 股份 |
| BANK OF AMERICA CORP /DE/ | $2487008 | 435553 | 0.28% | 股份 |
| Ikarian Capital, LLC | $2456693 | 430244 | 0.27% | 股份 |
| MOORE CAPITAL MANAGEMENT, LP | $2428646 | 425332 | 0.27% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2352520 | 412000 | 0.26% | 买入期权 |
| Trexquant Investment LP | $2339199 | 409667 | 0.26% | 股份 |
| Susquehanna Portfolio Strategies, LLC | $2256763 | 395230 | 0.25% | 股份 |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $2253166 | 394600 | 0.25% | 股份 |
| DIADEMA PARTNERS LP | $2016772 | 353200 | 0.22% | 买入期权 |
| Engineers Gate Manager LP | $1821815 | 319057 | 0.20% | 股份 |
| DAFNA Capital Management LLC | $1700507 | 297812 | 0.19% | 股份 |
| Jump Financial, LLC | $1700438 | 297800 | 0.19% | 股份 |
| STATE OF WISCONSIN INVESTMENT BOARD | $1635201 | 286375 | 0.18% | 股份 |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $1427643 | 250025 | 0.16% | 股份 |
| UBS Group AG | $1413653 | 247575 | 0.16% | 股份 |
| Swiss National Bank | $1396666 | 244600 | 0.15% | 股份 |
| CITADEL ADVISORS LLC | $1340137 | 234700 | 0.15% | 买入期权 |
| CITIGROUP INC | $1296318 | 227026 | 0.14% | 股份 |
| Cinctive Capital Management LP | $1231921 | 215748 | 0.14% | 股份 |
| MARSHALL WACE, LLP | $1202566 | 210607 | 0.13% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1086042 | 190200 | 0.12% | 卖出期权 |
| RHUMBLINE ADVISERS | $1082480 | 189578 | 0.12% | 股份 |
| Bank of New York Mellon Corp | $1002413 | 175554 | 0.11% | 股份 |
| Squarepoint Ops LLC | $989457 | 173285 | 0.11% | 股份 |
| Rafferty Asset Management, LLC | $989423 | 173279 | 0.11% | 股份 |
| Point72 Europe (London) LLP | $923726 | 302861 | 0.10% | 股份 |
| OSAIC HOLDINGS, INC. | $842767 | 147595 | 0.09% | 股份 |
| ALLIANCEBERNSTEIN L.P. | $815710 | 147240 | 0.09% | 股份 |
| WELLS FARGO & COMPANY/MN | $809090 | 141697 | 0.09% | 股份 |
| BlackRock, Inc. | $782276 | 137001 | 0.09% | 股份 |
| WELLINGTON MANAGEMENT GROUP LLP | $738234 | 129288 | 0.08% | 股份 |
| VICTORY CAPITAL MANAGEMENT INC | $727100 | 127338 | 0.08% | 股份 |
| BOOTHBAY FUND MANAGEMENT, LLC | $685937 | 120129 | 0.08% | 股份 |
| IEQ CAPITAL, LLC | $685257 | 120010 | 0.08% | 股份 |
| J. Goldman & Co LP | $662623 | 116046 | 0.07% | 股份 |
| XTX Topco Ltd | $640359 | 112147 | 0.07% | 股份 |
| Vanguard Global Advisers, LLC | $582803 | 102067 | 0.06% | 股份 |
| Quarry LP | $571000 | 100000 | 0.06% | 股份 |
| Russell Investments Group, Ltd. | $566711 | 99249 | 0.06% | 股份 |
| SCS Capital Management LLC | $565290 | 99000 | 0.06% | 股份 |
| Nuveen, LLC | $564508 | 98863 | 0.06% | 股份 |
| MetLife Investment Management, LLC | $519639 | 91005 | 0.06% | 股份 |
| JANE STREET GROUP, LLC | $516755 | 90500 | 0.06% | 买入期权 |
| J. Safra Sarasin Holding AG | $516681 | 90487 | 0.06% | 股份 |
| CITADEL ADVISORS LLC | $507619 | 88900 | 0.06% | 卖出期权 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $505438 | 88518 | 0.06% | 股份 |
| CAPTRUST FINANCIAL ADVISORS | $501960 | 87909 | 0.06% | 股份 |
| PROFUND ADVISORS LLC | $499676 | 87509 | 0.06% | 股份 |
| VANGUARD ASSET MANAGEMENT, Ltd | $453865 | 79486 | 0.05% | 股份 |
| DNB Asset Management AS | $417669 | 73147 | 0.05% | 股份 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $408448 | 71532 | 0.05% | 股份 |
| Virtus Investment Advisers, LLC | $396662 | 69468 | 0.04% | 股份 |
| Jain Global LLC | $369545 | 64719 | 0.04% | 股份 |
| China Universal Asset Management Co., Ltd. | $354454 | 62076 | 0.04% | 股份 |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $354437 | 62073 | 0.04% | 股份 |
| DIVERSIFIED TRUST CO | $352860 | 61797 | 0.04% | 股份 |
| Invesco Ltd. | $351696 | 61593 | 0.04% | 股份 |
公司内部人士 11 位内幕人士 · 3 位高管 · 7 位董事
| 内部人士 | 角色 | 上次活动 | 持股数量 | 买入 12个月 | 卖出 12个月 | 净额 12个月 |
|---|---|---|---|---|---|---|
| Jennifer Lew | EVP & Chief Financial Officer | 2023年7月11日 S | 47460 | 0 | 0 | $0 |
| Ted Yednock | EVP & CHIEF INNOVATION OFFICER | 2026年6月11日 M | 184807 | 0 | 0 | $0 |
| Michael Overdorf | EVP & Chief Business Officer | 2023年7月11日 S | 45802 | 0 | 0 | $0 |
| Bettina M. Cockroft | 董事 | 2026年6月11日 A | — | 0 | 0 | $0 |
| William H. Carson | 董事 | 2026年6月11日 A | — | 0 | 0 | $0 |
| Jung Choi | 董事 | 2026年6月11日 A | — | 0 | 0 | $0 |
| William D. Waddill | 董事 | 2026年6月11日 A | — | 0 | 0 | $0 |
| William A Jones JR | 董事 | 2026年6月11日 A | — | 0 | 0 | $0 |
| Satter Muneer A | 董事 | 2026年6月11日 A | 10342134 | 6 | 0 | $11974803 |
| Ricky Sun | 董事 | 2021年6月2日 A | — | 0 | 0 | $0 |
| Mark S. Blumenkranz | — | 2026年8月10日 A | — | 0 | 0 | $0 |
来自SEC表格3/4/5申报的内部人士；净额=仅公开市场买卖
激进投资者及 5%+ 股东 3 持仓
提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权，意图影响发行人（激进股东持股、董事会活动、并购）。每一行显示该申报人持仓的最新已知状态。
| 申报人 | 已申报 | 持股 | 状态 | 目的 | 申报 |
|---|---|---|---|---|---|
| Satter Muneer A | 2025年11月21日 | 7.20% | 修订 | — | SEC |
| Muneer A. Satter ×2 申报 | 2023年2月17日 | — | 初始申报 | — | SEC |
| Clarus Lifesciences III, L.P., Clarus Ventures III GP, L.P., Blackstone Clarus III L.L.C., Blackstone Holdings II L.P., Blackstone Holdings I/II GP L.L.C., Blackstone Inc., Blackstone Group Management L.L.C., Stephen A. Schwarzman ×2 申报 | 2021年8月27日 | — | 初始申报 | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF持仓 由 38 只交易所交易基金持有
权重仅反映直接股权持仓（N-PORT）；杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。
| 基金 | 权重 | 单位 | 截至 | 来源 |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 0.87% | 55535 NS | 2026年4月30日 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0.25% | 218784 NS | 2026年4月30日 | N-PORT |
| BIB · ProShares Trust | 0.04% | 5349 NS | 2026年5月31日 | N-PORT |
| RSSL · Global X Funds | 0.02% | 57102 NS | 2026年4月30日 | N-PORT |
| ITWO · ProShares Trust | 0.02% | 6206 NS | 2026年5月31日 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0.02% | 637833 NS | 2026年5月31日 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0.01% | 54687 NS | 2026年4月30日 | N-PORT |
| UWM · ProShares Trust | 0.01% | 4853 NS | 2026年5月31日 | N-PORT |
| URTY · ProShares Trust | 0.01% | 4907 NS | 2026年5月31日 | N-PORT |
| DFAS · Dimensional ETF Trust | 0.01% | 179974 NS | 2026年4月30日 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0.00% | 69949 NS | 2026年5月31日 | N-PORT |
| HDG · ProShares Trust | 0.00% | 123 NS | 2026年5月31日 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0.00% | 3773 NS | 2026年5月31日 | N-PORT |
| DFAC · Dimensional ETF Trust | 0.00% | 180473 NS | 2026年4月30日 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0.00% | 9567 NS | 2026年5月31日 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0.00% | 79390 NS | 2026年5月31日 | N-PORT |
| DFAU · Dimensional ETF Trust | 0.00% | 15085 NS | 2026年4月30日 | N-PORT |
| DFUS · Dimensional ETF Trust | 0.00% | 13707 NS | 2026年4月30日 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | 2026年7月15日 | 每日 |
| VTI · VANGUARD INDEX FUNDS | — | — | 2026年7月15日 | 每日 |
| VFMO · VANGUARD WELLINGTON FUND | — | — | 2026年7月30日 | 每日 |
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | 2026年7月15日 | 每日 |
| VTWG · VANGUARD SCOTTSDALE FUNDS | — | — | 2026年7月15日 | 每日 |
| VTHR · VANGUARD SCOTTSDALE FUNDS | — | — | 2026年7月15日 | 每日 |
| ITOT · iShares Trust | — | — | 2026年8月5日 | 每日 |
| IWV · iShares Trust | — | — | 2026年8月18日 | 每日 |
| IWO · iShares Trust | — | — | 2026年8月18日 | 每日 |
| IWM · iShares Trust | — | — | 2026年8月18日 | 每日 |
| IBB · iShares Trust | — | — | 2026年8月18日 | 每日 |
| IWC · iShares Trust | — | — | 2026年8月18日 | 每日 |
| PRFZ · Invesco Exchange-Traded Fund Trust | — | — | 2026年7月13日 | 每日 |
| OMFS · Invesco Exchange-Traded Self-Inde... | — | — | 2026年7月13日 | 每日 |
| VHT · VANGUARD WORLD FUND | — | — | 2026年7月20日 | 每日 |
| ISCB · iShares Trust | — | — | 2026年8月5日 | 每日 |
| ISCV · iShares Trust | — | — | 2026年8月5日 | 每日 |
| IBRN · iShares Trust | — | — | 2026年8月6日 | 每日 |
| WSML · iShares Trust | — | — | 2026年8月5日 | 每日 |
| IBBQ · Invesco Exchange-Traded Fund Trus... | — | — | 2026年7月20日 | 每日 |