VSTM Verastem, Inc. - Common Stock
$7.51
价格 · 八月 19, 2026
截至...的财报数据 八月 6, 2026
52周区间
$3–$11
52% of range
分析师评级
BUY
15 analysts
目标价
$15
+96% upside
P/E (TTM)
-2.5
ROE
-449.2%
净利润率
-677.6%
VSTM 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围
价格
$7.51
市值
$584M
P/E (TTM)
-2.5
每股收益 (TTM)
$-3.02
营收 (TTM)
$31M
股息收益率
—
ROE
-449.2%
负债/权益
—
52周区间
$3 – $11
VSTM 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图
Configure
10年表现 收入、净利润、利润率和每股收益趋势
营收与净利润
$31M
2018-12-31
→
2025-12-31
EPS
$-3.02
2016-12-31
→
2025-12-31
自由现金流
—
2016-12-31
→
2024-12-31
利润率
-677.6%
估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜？
指标
5年趋势
VSTM
同行中位数
P/E (TTM)
-2.5
19.6
P/S (TTM) (市销率 (TTM))
18.9
24.9
P/B (市净率)
10.2
3.1
盈利能力 毛利率、营业利润率和净利率；股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)
指标
5年趋势
VSTM
同行中位数
Operating Margin (营业利润率)
-550.3%
—
Net Profit Margin (净利润率)
-677.6%
-298.0%
ROA
-120.4%
-56.6%
ROE
-449.2%
-70.8%
财务健康 债务、流动性、偿付能力 — 资产负债表强度
指标
5年趋势
VSTM
同行中位数
Current Ratio (流动比率)
3.1
5.2
Quick Ratio (速动比率)
2.8
—
成长 营收、每股收益 (EPS) 和净利润增长：同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)
指标
5年趋势
VSTM
同行中位数
Revenue YoY (营收同比增长)
209.1%
—
Revenue CAGR 3Y (营收3年复合年增长率)
128.4%
—
Revenue CAGR 5Y (营收5年复合年增长率)
-19.0%
—
资本效率 资产周转率、库存周转率、应收账款周转率
指标
5年趋势
VSTM
同行中位数
VSTM 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间
买入
15 位分析师
- 强烈买入 5 33.3%
- 买入 9 60.0%
- 持有 1 6.7%
- 卖出 0 0.0%
- 强烈卖出 0 0.0%
12个月价格目标
8 位分析师 · 2026-08-13
中位数
$15.00
← 低于所有目标
$7.51
最低
$9.00
最高
$18.00
中位数目标
$15.00
+99.7%
平均目标
$14.75
+96.4%
收益历史 每股收益实际值 vs 预估值，惊喜%，达标率，下次财报日期
平均惊喜
-0.04%
| 期间 | EPS Actual | EPS 预期 | 惊喜 |
|---|---|---|---|
| 2026年6月30日 | $-0.35 | $-0.44 | 0.09% |
| 2026年3月31日 | $-0.46 | $-0.47 | 0.01% |
| 2025年12月31日 | $-0.50 | $-0.55 | 0.05% |
| 2025年9月30日 | $-1.35 | $-0.65 | -0.70% |
| 2025年6月30日 | $-0.39 | $-0.76 | 0.37% |
| 2025年3月31日 | $-0.79 | $-0.73 | -0.06% |
同行比较（GICS 子行业） 关键指标与行业同行对比
| 股票代码 | 市值 | P/E | 营收同比增长 | 净利润率 | ROE | 毛利率 |
|---|---|---|---|---|---|---|
| VSTM | $600M | -2.6 | 209.1% | -677.6% | -449.2% | — |
| KYTX | $568M | -2.6 | — | — | -77.4% | — |
| PRLD | — | -2.2 | 73.4% | -819.6% | -137.7% | — |
| CCCC | $185M | -1.5 | 1.0% | -292.1% | -48.8% | — |
| EVMN | $540M | -1.5 | 85.7% | -529.8% | -401.2% | — |
| ZURA | — | — | — | — | — | — |
| CABA | $220M | -1.0 | — | — | -115.5% | — |
| MPLT | $773M | -0.9 | — | — | -151.1% | — |
| EDIT | $201M | -1.1 | 25.4% | -395.0% | -688.8% | — |
| PBYI | $300M | 9.8 | -0.91% | 13.6% | 26.5% | — |
| OCGN | $422M | -5.6 | 8.8% | -1537.4% | 1488.8% | — |
完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表
损益表 17
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue | $31M | $10M | · | $3M | $2M | $89M | $17M | $27M | |
| Cost of Revenue | · | · | · | · | · | · | · | $165.0K | |
| R&D Expense | $115M | $81M | $61M | $51M | $39M | $41M | $46M | $44M | |
| SG&A Expense | $81M | $44M | $31M | $25M | $24M | $63M | $101M | $77M | |
| Operating Expenses | $201M | $125M | $92M | $76M | $63M | $138M | $150M | $122M | |
| Operating Income | $-170M | $-115M | $-92M | $-73M | $-61M | $-49M | $-132M | $-95M | |
| Interest Expense | $1M | $5M | $4M | $2M | $10M | $16M | $21M | $6M | |
| Interest Income | $4M | $4M | $6M | $1M | $181.0K | $515.0K | $4M | $3M | |
| Other Non-op | $-203.0K | $-123.0K | $-109.0K | $47.0K | · | $-1M | $-641.0K | $26M | |
| Pretax Income | $-209M | $-130M | $-87M | $-74M | $-71M | $-68M | $-149M | $-72M | |
| Income Tax | · | $185.0K | · | $0 | $0 | $194.0K | $0 | $0 | |
| Net Income | $-209M | $-131M | $-87M | $-74M | $-71M | $-68M | $-149M | $-72M | |
| EPS (Basic) | $-3.02 | $-3.66 | $-3.96 | $-4.57 | $-4.90 | $-0.44 | $-2.00 | $-1.12 | |
| EPS (Diluted) | $-3.02 | $-3.66 | $-3.96 | $-4.57 | $-4.90 | $-0.44 | $-2.00 | $-1.37 | |
| Shares (Basic) | 69,309,000 | 35,713,000 | 22,054,000 | 16,138,000 | 14,535,000 | 153,330,000 | 74,578,000 | 64,962,000 | |
| Shares (Diluted) | 69,309,000 | 35,713,000 | 22,054,000 | 16,138,000 | 14,535,000 | 153,330 | 74,578,000 | 69,321,000 | |
| EBITDA | $-170M | $-115M | $-92M | $-73M | $-61M | $-49M | $-132M | $-95M |
资产负债表 23
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $205M | $89M | $78M | $75M | $21M | $68M | $44M | $130M | |
| Inventory | $2M | · | · | · | · | · | $3M | $327.0K | |
| Prepaid Expense | $8M | $6M | $7M | $5M | $5M | $3M | $4M | $3M | |
| Current Assets | $223M | $95M | $144M | $93M | $106M | $145M | $85M | $253M | |
| PP&E (Net) | · | $32.0K | $37.0K | $92.0K | $210.0K | $416.0K | $947.0K | $1M | |
| PP&E (Gross) | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Accum. Depreciation | $2M | $2M | $2M | $2M | $2M | $1M | $938.0K | $509.0K | |
| Intangibles | $16M | · | · | · | · | · | $20M | $22M | |
| Other Non-current Assets | $6M | $5M | $5M | $58.0K | $169.0K | $33.0K | $812.0K | $790.0K | |
| Total Assets | $246M | $102M | $150M | $95M | $109M | $154M | $145M | $277M | |
| Accounts Payable | $12M | $4M | $7M | $5M | $2M | $2M | $10M | $10M | |
| Accrued Liabilities | $54M | $26M | $18M | $15M | $16M | $15M | $19M | $21M | |
| Current Liabilities | $72M | $31M | $26M | $22M | $19M | $17M | $30M | $37M | |
| Capital Leases | · | $535.0K | $530.0K | $1M | $2M | $3M | $3M | · | |
| Other Non-current Liabilities | · | · | · | · | · | · | $870.0K | $1M | |
| Total Liabilities | $189M | $130M | $71M | $48M | $21M | $39M | $138M | $153M | |
| Long-term Debt | · | $41M | $40M | $25M | · | · | $35M | $25M | |
| Common Stock | $8.0K | $4.0K | $3.0K | $2.0K | $19.0K | $17.0K | $8.0K | $7.0K | |
| Retained Earnings | $-1.16B | $-956M | $-825M | $-738M | $-664M | $-593M | $-525M | $-376M | |
| AOCI | $5M | · | $13.0K | · | $34.0K | $53.0K | $14.0K | $127.0K | |
| Stockholders' Equity | $57M | $-29M | $57M | $47M | $88M | $115M | $7M | $124M | |
| Liabilities + Equity | $246M | $102M | $150M | $95M | $109M | $154M | $145M | $277M | |
| Shares Outstanding | 77,740,000 | 44,784,000 | 25,281,000 | 16,712,000 | 185,286,000 | 170,456,000 | 80,118,000 | 73,806,000 |
现金流 15
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $9M | $7M | $6M | $6M | $8M | $8M | $9M | $7M | |
| Deferred Tax | · | · | · | $0 | $0 | $0 | $0 | $0 | |
| Amort. of Intangibles | $698.0K | · | · | · | · | $793.0K | $2M | $423.0K | |
| Restructuring | · | · | · | · | $0 | $5M | · | · | |
| Operating Cash Flow | $-138M | $-105M | $-86M | $-64M | $-54M | $-34M | $-139M | $-75M | |
| CapEx | · | $28.0K | · | · | $196.0K | $33.0K | $7.0K | $2M | |
| Investing Cash Flow | $-10M | $60M | $-44M | $66M | $87.0K | $-47M | $90M | $-138M | |
| Net Debt Issued | $-43M | · | $-300.0K | · | · | $-37M | · | · | |
| Stock Issued | $197M | $14M | $91M | $27M | $7M | $106M | · | $105M | |
| Net Stock Activity | $197M | $14M | $91M | $27M | $7M | $106M | · | · | |
| Financing Cash Flow | $263M | $55M | $134M | $52M | $7M | $70M | $-2M | $261M | |
| Net Change in Cash | $116M | $10M | $3M | $54M | $-47M | $-11M | $-51M | $48M | |
| Taxes Paid | $185.0K | · | · | · | · | · | · | · | |
| Free Cash Flow | · | $-105M | · | · | $-54M | $-34M | $-139M | $-76M | |
| Levered FCF | · | $-109M | · | · | $-64M | $-49M | · | · |
盈利能力 7
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -550.3% | -1149.6% | · | -2809.6% | -2991.2% | -55.8% | -758.1% | -354.8% | |
| Net Margin | -677.6% | -1306.4% | · | -2843.3% | -3468.1% | -76.5% | -854.8% | -271.1% | |
| Pretax Margin | -677.6% | -1304.5% | · | -2843.3% | -3468.1% | -76.3% | · | · | |
| EBITDA Margin | -550.3% | -1149.6% | · | -2809.6% | -2991.2% | -55.8% | -758.1% | -354.8% | |
| ROA | -120.4% | -104.0% | -71.4% | -72.5% | -54.1% | -45.2% | -70.7% | -39.5% | |
| ROE | -449.2% | 1465.1% | -124.3% | -133.9% | -77.7% | -55.3% | -1040.1% | -62.5% | |
| ROIC | · | 398.4% | · | -153.9% | -70.1% | -42.9% | · | · |
流动性与偿付能力 3
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.1 | 3.1 | 5.4 | 4.3 | 5.7 | 8.5 | 2.8 | 6.8 | |
| Quick Ratio | 2.8 | 2.9 | 3.0 | 3.5 | 1.1 | 4.0 | 1.5 | 3.5 | |
| Interest Coverage | -149.5 | -25.2 | -22.2 | -34.1 | -6.2 | -3.1 | -6.4 | -16.3 |
效率 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.2 | 0.1 | · | 0.0 | 0.0 | 0.6 | 0.1 | 0.1 | |
| Inventory Turnover | · | · | · | · | · | · | · | 1.0 |
增长率 3
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | 209.1% | · | · | 26.5% | -97.7% | · | · | · | |
| Revenue CAGR 3Y | 128.4% | 69.5% | · | · | · | · | · | · | |
| Revenue CAGR 5Y | -19.0% | · | · | · | · | · | · | · |
估值 (TTM) 10
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $31M | $10M | $4M | $3M | $2M | $89M | $17M | $27M | |
| Net Income TTM | $-209M | $-131M | $-87M | $-74M | $-71M | $-68M | $-149M | $-72M | |
| Market Cap | $600M | $232M | $206M | $963M | $4.56B | $4.36B | $1.29B | $2.98B | |
| P/E | -2.6 | -1.4 | -2.1 | -1.1 | -5.0 | -58.1 | -8.0 | -29.4 | |
| P/S | 19.4 | 23.2 | 50.1 | 370.8 | 2220.2 | 49.2 | 73.8 | 111.4 | |
| P/B | 10.5 | -8.0 | 3.6 | 20.3 | 52.1 | 37.8 | 179.6 | 23.9 | |
| P / Tangible Book | 14.7 | · | 3.6 | 20.3 | 52.1 | 37.8 | · | · | |
| P / Cash Flow | -4.4 | -2.2 | -2.4 | -15.1 | -85.2 | -130.0 | -9.3 | -39.9 | |
| P / FCF | · | -2.2 | · | · | -84.9 | -129.9 | -9.3 | -39.1 | |
| Earnings Yield | -39.1% | -70.8% | -48.6% | -95.2% | -19.9% | -1.7% | -12.4% | -3.4% |
损益表 16
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $40M | $19M | $18M | $11M | $2M | · | $0 | $0 | $10M | · | · | · | · | $0 | $0 | $0 | |
| R&D Expense | $41M | $38M | $32M | $29M | $25M | $29M | $21M | $25M | $18M | $18M | $14M | $13M | $12M | $11M | $11M | $15M | |
| SG&A Expense | $27M | $22M | $24M | $21M | $21M | $15M | $11M | $12M | $10M | $10M | $7M | $7M | $7M | $6M | $6M | $7M | |
| Operating Expenses | $73M | $64M | $59M | $52M | $46M | $44M | $32M | $37M | $28M | $28M | $21M | $20M | $19M | $17M | $18M | $21M | |
| Operating Income | $-33M | $-45M | $-41M | $-41M | $-44M | $-44M | $-32M | $-37M | $-18M | $-28M | $-21M | $-20M | $-19M | $-17M | $-18M | $-21M | |
| Interest Expense | $360.0K | $382.0K | $415.0K | $319.0K | $212.0K | $192.0K | $1M | $1M | $1M | $1M | $1M | $1M | $769.0K | $724.0K | $717.0K | $640.0K | |
| Interest Income | $1M | $1M | $1M | $1M | $822.0K | $960.0K | $968.0K | $831.0K | $983.0K | $1M | $2M | $1M | $976.0K | $769.0K | $316.0K | $84.0K | |
| Other Non-op | $-52.0K | $-61.0K | $-16.0K | $-37.0K | $-110.0K | $-40.0K | $8.0K | $-77.0K | $-24.0K | $-30.0K | $-13.0K | $-40.0K | $-7.0K | $-7.0K | $20.0K | $6.0K | |
| Pretax Income | $-34M | · | · | · | $-26M | · | · | · | · | · | · | · | · | · | · | · | |
| Income Tax | $816.0K | $0 | · | $0 | $0 | $0 | $185.0K | $0 | $0 | $0 | $0 | $0 | $0 | · | $0 | $0 | |
| Net Income | $-35M | $-37M | $-33M | $-99M | $-26M | $-52M | $-65M | $-24M | $-8M | $-34M | $-20M | $-24M | $-16M | $-17M | $-18M | $-22M | |
| EPS (Basic) | $-0.35 | $-0.37 | $-0.32 | $-1.35 | $-0.39 | $-0.96 | $-1.49 | $-0.60 | $-0.31 | $-1.26 | $-0.75 | $-1.37 | $-0.94 | $-1.97 | $-1.10 | $-1.41 | |
| EPS (Diluted) | $-0.35 | $-0.46 | $-0.09 | $-1.35 | $-0.62 | $-0.96 | $-1.49 | $-0.60 | $-0.31 | $-1.26 | $-0.75 | $-1.37 | $-0.08 | $-4.27 | $-0.09 | $-0.12 | |
| Shares (Basic) | 100,116,000 | 98,292,000 | -124,164,000 | 73,157,000 | 66,143,000 | 54,173,000 | -58,238,000 | 40,258,000 | 26,861,000 | 26,832,000 | 26,790,000 | 17,732,000 | 16,723,000 | -202,095,000 | 16,430,000 | 15,539,000 | |
| Shares (Diluted) | 100,116,000 | 99,148,000 | -132,058,000 | 73,157,000 | 74,037,000 | 54,173,000 | -58,238,000 | 40,258,000 | 26,861,000 | 26,832,000 | 26,790,000 | · | 200,679,000 | -553,740,000 | 197,151,000 | 186,463,000 | |
| EBITDA | $-33M | $-45M | · | $-41M | $-44M | $-44M | · | $-37M | $-18M | $-28M | $-21M | $-20M | $-19M | · | $-18M | $-21M |
资产负债表 26
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $136M | $166M | $205M | $138M | $164M | $118M | $89M | $113M | $83M | $81M | $95M | $183M | $97M | · | $78M | $64M | |
| Short-term Investments | · | $16M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Inventory | $2M | $2M | $2M | $2M | $1M | · | · | · | · | · | · | · | · | · | · | · | |
| Prepaid Expense | $8M | $9M | $8M | $8M | $7M | $7M | $6M | $7M | $5M | $7M | $9M | $7M | $8M | · | $5M | $3M | |
| Current Assets | $176M | $203M | $223M | $154M | $174M | $125M | $95M | $121M | $100M | $118M | $174M | $190M | $119M | · | $109M | $98M | |
| PP&E (Net) | · | · | · | $20.0K | $21.0K | $22.0K | $32.0K | $39.0K | $46.0K | $52.0K | $35.0K | $40.0K | $62.0K | · | $121.0K | $151.0K | |
| PP&E (Gross) | · | · | $2M | · | · | · | $2M | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $2M | · | · | · | $2M | · | · | · | · | · | · | · | · | · | |
| Intangibles | $16M | $16M | $16M | $17M | $16M | · | · | · | · | · | · | · | · | · | · | · | |
| Other Non-current Assets | $12M | $6M | $6M | $5M | $5M | $6M | $5M | $5M | $5M | $5M | $56.0K | $20.0K | $36.0K | · | $47.0K | $84.0K | |
| Total Assets | $207M | $228M | $246M | $177M | $196M | $132M | $102M | $126M | $106M | $124M | $176M | $192M | $121M | · | $111M | $100M | |
| Accounts Payable | $18M | $10M | $12M | $10M | $8M | $7M | $4M | $4M | $7M | $7M | $5M | $5M | $5M | · | $5M | $2M | |
| Accrued Liabilities | $54M | $51M | $54M | $45M | $38M | $25M | $26M | $22M | $17M | $17M | $16M | $14M | $14M | · | $15M | $18M | |
| Short-term Debt | $214.0K | $529.0K | · | $188.0K | $467.0K | $740.0K | · | $133.0K | $526.0K | $911.0K | $146.0K | $579.0K | $1M | · | · | · | |
| Current Liabilities | $78M | $67M | $72M | $60M | $50M | $36M | $31M | $37M | $30M | $27M | $24M | $21M | $22M | · | $22M | $20M | |
| Capital Leases | $2M | $2M | · | · | · | $271.0K | $535.0K | · | · | $270.0K | $780.0K | $1M | $1M | · | $2M | $2M | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | · | · | $51.0K | · | · | · | · | · | |
| Total Liabilities | $157M | $146M | $189M | $192M | $160M | $164M | $130M | $94M | $66M | $77M | $72M | $69M | $67M | · | $48M | $47M | |
| Long-term Debt | · | · | · | · | · | · | $41M | $41M | $40M | $40M | $40M | $40M | $40M | · | $24M | $24M | |
| Total Debt | $214.0K | $529.0K | · | $188.0K | $467.0K | $740.0K | · | $133.0K | · | $911.0K | $146.0K | $579.0K | $1M | · | · | · | |
| Common Stock | $9.0K | $9.0K | $8.0K | $7.0K | $6.0K | $5.0K | $4.0K | $4.0K | $3.0K | $3.0K | $3.0K | $3.0K | $20.0K | · | $21.0K | $19.0K | |
| Retained Earnings | $-1.24B | $-1.20B | $-1.16B | $-1.13B | $-1.03B | $-1.01B | $-956M | $-891M | $-867M | $-859M | $-798M | $-778M | $-753M | · | $-721M | $-703M | |
| AOCI | $8M | $9M | $5M | $3M | $5M | $7M | · | · | · | $-4.0K | $49.0K | $1.0K | $6.0K | · | $-39.0K | $-130.0K | |
| Stockholders' Equity | $50M | $82M | $57M | $-16M | $36M | $-32M | $-29M | $11M | $19M | $25M | $83M | $102M | $33M | $47M | $63M | $54M | |
| Liabilities + Equity | $207M | $228M | $246M | $177M | $196M | $132M | $102M | $126M | $106M | $124M | $176M | $192M | $121M | · | $111M | $100M | |
| Shares Outstanding | 90,482,000 | 87,843,000 | 77,740,000 | 66,749,000 | 61,523,000 | 51,490,000 | 44,784,000 | 40,262,000 | 26,876,000 | 25,308,000 | 25,265,000 | 25,242,000 | 200,541,000 | · | 210,084,000 | 187,613,000 |
现金流 11
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $3M | $2M | $2M | $2M | $3M | $2M | $2M | $2M | $2M | $1M | $2M | $1M | $1M | $1M | $1M | $2M | |
| Amort. of Intangibles | $280.0K | $279.0K | $280.0K | $290.0K | · | · | · | · | · | · | · | · | · | · | · | · | |
| Operating Cash Flow | $-44M | $-52M | $-30M | $-36M | $-33M | $-39M | $-25M | $-24M | $-28M | $-28M | $-17M | $-20M | $-20M | $-17M | $-15M | $-13M | |
| CapEx | · | · | · | · | · | · | $0 | $0 | $7.0K | $21.0K | · | · | · | · | · | · | |
| Investing Cash Flow | $16M | $-16M | $-1M | · | · | · | $0 | $0 | $29M | $31M | $-70M | $14M | $-804.0K | $13M | $5M | $29M | |
| Net Debt Issued | · | · | · | · | · | $-43M | · | · | · | · | · | · | · | · | · | · | |
| Stock Issued | · | · | $97M | $0 | $70M | $30M | $0 | · | · | · | $-486.0K | · | · | $0 | $26M | $1M | |
| Net Stock Activity | · | · | · | · | · | $30M | · | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $-2M | $29M | $99M | $18M | $79M | $67M | $742.0K | $54M | $-405.0K | $846.0K | $-891.0K | $91M | $44M | $0 | $26M | $708.0K | |
| Net Change in Cash | $-29M | $-39M | $67M | $-27M | $47M | $29M | $-24M | $30M | $1M | $4M | $-88M | $86M | $23M | $-4M | $15M | $17M | |
| Free Cash Flow | · | · | · | · | · | · | · | · | · | $-28M | · | · | · | · | · | · |
盈利能力 7
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -81.6% | -240.5% | · | -362.2% | -2047.9% | · | · | · | -182.8% | · | · | · | · | · | · | · | |
| Net Margin | -86.5% | -196.0% | · | -876.3% | -1213.6% | · | · | · | -82.6% | · | · | · | · | · | · | · | |
| Pretax Margin | -84.5% | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| EBITDA Margin | -81.6% | -240.5% | · | -362.2% | -2047.9% | · | · | · | -182.8% | · | · | · | · | · | · | · | |
| ROA | -17.2% | -20.4% | · | -65.0% | -13.4% | -43.9% | · | -15.8% | · | -27.7% | -13.9% | -16.6% | -13.3% | · | -16.2% | -19.6% | |
| ROE | -80.6% | -148.3% | · | 4411.9% | -37.7% | 767.2% | · | -50.9% | · | -116.6% | -27.4% | -31.2% | -29.7% | · | -22.8% | -30.9% | |
| ROIC | -66.7% | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · |
流动性与偿付能力 4
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.3 | 3.0 | · | 2.6 | 3.5 | 3.5 | · | 3.2 | · | 4.4 | 7.3 | 9.1 | 5.3 | · | 5.0 | 4.9 | |
| Quick Ratio | 1.7 | 2.7 | · | 2.3 | 3.3 | 3.3 | · | 3.0 | · | 3.0 | 4.0 | 8.8 | 4.3 | · | 3.6 | 3.2 | |
| Debt / Equity | 0.0 | 0.0 | · | -0.0 | 0.0 | -0.0 | · | 0.0 | · | 0.0 | 0.0 | 0.0 | 0.0 | · | · | · | |
| Interest Coverage | -90.9 | -117.5 | · | -127.6 | -206.4 | -230.1 | · | -32.3 | -16.1 | -24.8 | -18.9 | -18.1 | -25.2 | · | -24.7 | -33.4 |
效率 1
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.2 | 0.1 | · | 0.1 | 0.0 | · | · | · | · | · | · | · | · | · | · | · |
估值 (TTM) 14
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $72M | · | · | · | · | · | · | · | · | $4M | $4M | $4M | $4M | · | $4M | $4M | |
| Net Income TTM | $-196M | $-213M | · | $-201M | $-110M | $-118M | · | $-86M | $-86M | $-94M | $-78M | $-80M | $-73M | · | $-80M | $-79M | |
| Market Cap | $346M | $466M | · | $589M | $255M | $310M | · | $120M | · | $299M | $205M | $188M | $1.01B | · | $2.14B | $2.61B | |
| Enterprise Value | $210M | $284M | · | $452M | $91M | $194M | · | $7M | · | $218M | $111M | $5M | $914M | · | · | · | |
| P/E | -1.4 | -1.6 | · | -2.5 | -1.7 | -1.9 | · | -1.0 | -0.8 | -3.4 | -3.6 | -4.5 | -13.3 | · | -23.7 | -31.6 | |
| P/S | 4.8 | · | · | · | · | · | · | · | · | 72.8 | 50.0 | 45.8 | 246.3 | · | 522.1 | 636.3 | |
| P/B | 6.9 | 5.7 | · | -38.0 | 7.1 | -9.6 | · | 10.9 | · | 11.9 | 2.5 | 1.8 | 30.6 | · | 34.1 | 48.5 | |
| P / Tangible Book | 10.1 | 7.1 | · | · | 12.5 | · | · | 10.9 | · | 11.9 | 2.5 | 1.8 | 30.6 | · | 34.1 | 48.5 | |
| P / Cash Flow | · | -8.9 | · | · | · | -8.0 | · | · | · | -10.5 | · | · | -49.8 | · | · | · | |
| P / FCF | · | · | · | · | · | · | · | · | · | -10.5 | · | · | · | · | · | · | |
| EV / EBITDA | -6.4 | -6.3 | · | -11.1 | -2.1 | -4.4 | · | -0.2 | · | -7.8 | -5.2 | -0.3 | -47.3 | · | · | · | |
| EV / FCF | · | · | · | · | · | · | · | · | · | -7.7 | · | · | · | · | · | · | |
| EV / Revenue | 2.9 | · | · | · | · | · | · | · | · | 53.2 | 26.9 | 1.3 | 222.8 | · | · | · | |
| Earnings Yield | -72.8% | -64.0% | · | -40.0% | -60.0% | -51.9% | · | -97.7% | -123.8% | -29.3% | -28.2% | -22.3% | -7.5% | · | -4.2% | -3.2% |
财务报表 损益表、资产负债表、现金流量表 — 年度，近5年
损益表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 收入 | $31M | $10M | — | $3M | $2M |
| 营业利润率 % | -550.3% | -1149.6% | — | -2809.6% | -2991.2% |
| 净收入 | $-209M | $-131M | $-87M | $-74M | $-71M |
| 稀释后每股收益 (EPS) | $-3.02 | $-3.66 | $-3.96 | $-4.57 | $-4.90 |
资产负债表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 流动比率 | 3.1 | 3.1 | 5.4 | 4.3 | 5.7 |
| 速动比率 | 2.8 | 2.9 | 3.0 | 3.5 | 1.1 |
现金流
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 自由现金流 | — | $-105M | — | — | $-54M |
我的指标 您的个人关注列表 — 来自完整基本面的选定行
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机构持有人 (13F) 174 家申报者 · $309.3M 总计 · 截至 2026年6月30日
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
机构活动 — Q2 2026 与上一季度对比
| 新仓位 | 已退出持仓 | 增加 | 减少 | 净股数变动 |
|---|---|---|---|---|
| 41 (0 与上一季度对比) | 29 (+9 与上一季度对比) | 59 (-8 与上一季度对比) | 39 (+9 与上一季度对比) | +12.4M |
与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天，外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过，优先显示最近一个已完整报告的季度对。
| 机构 | 价值 | 股份 | % 已追踪的13F | 类型 |
|---|---|---|---|---|
| ARMISTICE CAPITAL, LLC | $26831680 | 7024000 | 8.68% | 股份 |
| RTW INVESTMENTS, LP | $25348729 | 6635793 | 8.20% | 股份 |
| Deep Track Capital, LP | $21930047 | 5740850 | 7.09% | 股份 |
| STATE STREET CORP | $19611341 | 5133859 | 6.34% | 股份 |
| Rosalind Advisors, Inc. | $15228464 | 3986509 | 4.92% | 股份 |
| VANGUARD CAPITAL MANAGEMENT LLC | $14712761 | 3851508 | 4.76% | 股份 |
| Nantahala Capital Management, LLC | $13694012 | 3584820 | 4.43% | 股份 |
| Stonepine Capital Management, LLC | $12795575 | 3349627 | 4.14% | 股份 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $12479443 | 3266870 | 4.04% | 股份 |
| Foresite Capital Management VI LLC | $12020130 | 3146631 | 3.89% | 股份 |
| BAKER BROS. ADVISORS LP | $9547471 | 2499338 | 3.09% | 股份 |
| Alyeska Investment Group, L.P. | $8746368 | 2289625 | 2.83% | 股份 |
| GOLDMAN SACHS GROUP INC | $8672133 | 2270192 | 2.80% | 股份 |
| MILLENNIUM MANAGEMENT LLC | $7937971 | 2078003 | 2.57% | 股份 |
| Opaleye Management Inc. | $6876000 | 1800000 | 2.22% | 股份 |
| GEODE CAPITAL MANAGEMENT, LLC | $6742511 | 1764564 | 2.18% | 股份 |
| Balyasny Asset Management L.P. | $6442717 | 1686575 | 2.08% | 股份 |
| Qube Research & Technologies Ltd | $6220824 | 1628488 | 2.01% | 股份 |
| ACORN CAPITAL ADVISORS, LLC | $5612164 | 1469153 | 1.81% | 股份 |
| NEXTBio Capital Management LP | $4991976 | 1306800 | 1.61% | 股份 |
| FRANKLIN RESOURCES INC | $4221180 | 1105021 | 1.36% | 股份 |
| Pinnacle Financial Partners, Inc. | $4124148 | 1079620 | 1.33% | 股份 |
| BANK OF AMERICA CORP /DE/ | $3152921 | 825372 | 1.02% | 股份 |
| TWO SIGMA ADVISERS, LP | $3080218 | 398992 | 1.00% | 股份 |
| PANAGORA ASSET MANAGEMENT INC | $2547459 | 666874 | 0.82% | 股份 |
| J. Goldman & Co LP | $2483283 | 650074 | 0.80% | 股份 |
| SPHERA FUNDS MANAGEMENT LTD. | $2416654 | 632632 | 0.78% | 股份 |
| FMR LLC | $2392306 | 626258 | 0.77% | 股份 |
| VANGUARD FIDUCIARY TRUST CO | $2356413 | 616862 | 0.76% | 股份 |
| XTX Topco Ltd | $2146042 | 561791 | 0.69% | 股份 |
| BlackRock, Inc. | $2055099 | 537984 | 0.66% | 股份 |
| Jefferies Financial Group Inc. | $1896741 | 496529 | 0.61% | 股份 |
| Torray Investment Partners LLC | $1823878 | 477455 | 0.59% | 股份 |
| AIGH Capital Management LLC | $1791576 | 468999 | 0.58% | 股份 |
| TORONTO DOMINION BANK | $1758778 | 460413 | 0.57% | 股份 |
| Exome Asset Management LLC | $1638937 | 429041 | 0.53% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1585300 | 415000 | 0.51% | 卖出期权 |
| Palo Alto Investors LP | $1182997 | 309685 | 0.38% | 股份 |
| Jump Financial, LLC | $1174650 | 307500 | 0.38% | 股份 |
| Virtus Investment Advisers, LLC | $1083467 | 283630 | 0.35% | 股份 |
| Diametric Capital, LP | $1014358 | 265539 | 0.33% | 股份 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $931889 | 243950 | 0.30% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $910799 | 238429 | 0.29% | 股份 |
| DIMENSIONAL FUND ADVISORS LP | $877656 | 229753 | 0.28% | 股份 |
| CITADEL ADVISORS LLC | $872507 | 228405 | 0.28% | 股份 |
| Ikarian Capital, LLC | $816965 | 213865 | 0.26% | 股份 |
| RAYMOND JAMES FINANCIAL INC | $758423 | 198540 | 0.25% | 股份 |
| ALLIANCEBERNSTEIN L.P. | $620577 | 117090 | 0.20% | 股份 |
| Knott David M Jr | $592100 | 155000 | 0.19% | 股份 |
| CANTOR FITZGERALD, L. P. | $534800 | 140000 | 0.17% | 股份 |
| CITIGROUP INC | $441688 | 115625 | 0.14% | 股份 |
| ExodusPoint Capital Management, LP | $379082 | 99236 | 0.12% | 股份 |
| VANGUARD GROUP INC | $367271 | 47574 | 0.12% | 股份 |
| Rafferty Asset Management, LLC | $359859 | 94204 | 0.12% | 股份 |
| MILLENNIUM MANAGEMENT LLC | $326228 | 85400 | 0.11% | 买入期权 |
| RHUMBLINE ADVISERS | $319642 | 83678 | 0.10% | 股份 |
| BARCLAYS PLC | $312939 | 81921 | 0.10% | 股份 |
| ADAR1 Capital Management, LLC | $289556 | 75800 | 0.09% | 股份 |
| Brevan Howard Capital Management LP | $276141 | 72383 | 0.09% | 股份 |
| CITADEL ADVISORS LLC | $265872 | 69600 | 0.09% | 卖出期权 |
| BOOTHBAY FUND MANAGEMENT, LLC | $261827 | 68541 | 0.08% | 股份 |
| Nuveen Asset Management, LLC | $261773 | 50633 | 0.08% | 股份 |
| Man Group plc | $258221 | 67597 | 0.08% | 股份 |
| HSBC HOLDINGS PLC | $231620 | 59466 | 0.07% | 股份 |
| MetLife Investment Management, LLC | $226331 | 59249 | 0.07% | 股份 |
| Jain Global LLC | $211009 | 55238 | 0.07% | 股份 |
| ALGERT GLOBAL LLC | $195966 | 51300 | 0.06% | 股份 |
| TWO SIGMA INVESTMENTS, LP | $190824 | 49954 | 0.06% | 股份 |
| PROFUND ADVISORS LLC | $181389 | 47484 | 0.06% | 股份 |
| Quadrature Capital Ltd | $179471 | 46982 | 0.06% | 股份 |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $179059 | 46874 | 0.06% | 股份 |
| Quantinno Capital Management LP | $177007 | 46337 | 0.06% | 股份 |
| ENVESTNET ASSET MANAGEMENT INC | $170299 | 44581 | 0.06% | 股份 |
| Cetera Investment Advisers | $165834 | 43412 | 0.05% | 股份 |
| MERCER GLOBAL ADVISORS INC /ADV | $163190 | 42720 | 0.05% | 股份 |
| Bank of New York Mellon Corp | $160692 | 42066 | 0.05% | 股份 |
| Graham Capital Management, L.P. | $153300 | 40131 | 0.05% | 股份 |
| Caption Management, LLC | $146306 | 38300 | 0.05% | 买入期权 |
| Quantbot Technologies LP | $139961 | 36639 | 0.05% | 股份 |
| MORGAN STANLEY | $132191 | 34605 | 0.04% | 股份 |
| DIVERSIFIED TRUST CO | $123175 | 32245 | 0.04% | 股份 |
| Invesco Ltd. | $119150 | 31191 | 0.04% | 股份 |
| Aries Wealth Management | $117782 | 30833 | 0.04% | 股份 |
| Vanguard Global Advisers, LLC | $116586 | 30520 | 0.04% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $108870 | 28500 | 0.04% | 买入期权 |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $107828 | 19499 | 0.03% | 股份 |
| NewEdge Wealth, LLC | $106295 | 27826 | 0.03% | 股份 |
| Russell Investments Group, Ltd. | $106031 | 27757 | 0.03% | 股份 |
| SEI INVESTMENTS CO | $101696 | 26622 | 0.03% | 股份 |
| Nuveen, LLC | $101696 | 26622 | 0.03% | 股份 |
| CITADEL ADVISORS LLC | $95500 | 25000 | 0.03% | 买入期权 |
| JANE STREET GROUP, LLC | $95118 | 24900 | 0.03% | 卖出期权 |
| Verdad Advisers, LP | $92585 | 24237 | 0.03% | 股份 |
| WINTON GROUP Ltd | $92444 | 24200 | 0.03% | 股份 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $85010 | 22254 | 0.03% | 股份 |
| INTECH INVESTMENT MANAGEMENT LLC | $83822 | 21943 | 0.03% | 股份 |
| WELLINGTON MANAGEMENT GROUP LLP | $79838 | 20900 | 0.03% | 股份 |
| PRELUDE CAPITAL MANAGEMENT, LLC | $75151 | 19673 | 0.02% | 股份 |
| Police & Firemen's Retirement System of New Jersey | $74051 | 19385 | 0.02% | 股份 |
| LAZARD ASSET MANAGEMENT LLC | $70540 | 18466 | 0.02% | 股份 |
公司内部人士 42 位内幕人士 · 16 位高管 · 24 位董事
| 内部人士 | 角色 | 上次活动 | 持股数量 | 买入 12个月 | 卖出 12个月 | 净额 12个月 |
|---|---|---|---|---|---|---|
| Robert Forrester | President and CEO | 2019年1月3日 A | 221234 | 0 | 0 | $0 |
| Daniel Calkins | Chief Financial Officer | 2026年6月22日 S | 117238 | 0 | 6 | $-54546 |
| Julie B Feder | Chief Financial Officer | 2018年4月6日 A | — | 0 | 0 | $0 |
| John B Green | Chief Financial Officer | 2016年1月1日 A | 2500 | 0 | 0 | $0 |
| Michael Kauffman | President of Development | 2026年1月6日 A | 8666 | 0 | 1 | $-85500 |
| Matthew Ros | Chief Operating Officer | 2025年4月1日 A | 50000 | 0 | 0 | $0 |
| Frank Neumann | Chief Medical Officer | 2021年1月6日 A | 150000 | 0 | 0 | $0 |
| Steven H. Bloom | Chief Strategy Officer | 2019年1月3日 A | 3500 | 0 | 0 | $0 |
| Joseph M Lobacki | Executive VP & CCO | 2019年1月3日 A | 10700 | 0 | 0 | $0 |
| T. Le Ngocdiep MD, PhD | Chief Medical Officer | 2018年9月24日 A | — | 0 | 0 | $0 |
| Joseph Chiapponi | Vice President of Finance | 2017年1月9日 A | — | 0 | 0 | $0 |
| Gregory Berk | Chief Medical Officer | 2017年1月9日 A | — | 0 | 0 | $0 |
| Christoph H Westphal | Executive Chairman | 2015年6月30日 F | 665224 | 0 | 0 | $0 |
| Monica Singh | General Counsel | 2015年6月29日 P | 2000 | 0 | 0 | $0 |
| Joanna Horobin | Chief Medical Officer | 2015年1月8日 A | 750 | 0 | 0 | $0 |
| Jonathan Pachter | VP, Head of Research | 2014年8月1日 F | 62249 | 0 | 0 | $0 |
| Karin Anna Tollefson | 董事 | 2026年5月21日 A | 52666 | 0 | 0 | $0 |
| Paul A. Bunn | 董事 | 2026年5月21日 A | 44333 | 0 | 2 | $-137997 |
| Michelle Robertson | 董事 | 2026年5月21日 A | 52666 | 0 | 0 | $0 |
| Anil Kapur | 董事 | 2026年5月21日 A | 52666 | 0 | 0 | $0 |
| Brian M Stuglik | 董事 | 2026年5月21日 A | 137147 | 0 | 2 | $-11275 |
| John Johnson | 董事 | 2026年5月21日 A | 52666 | 0 | 0 | $0 |
| Eric K Rowinsky | 董事 | 2026年5月21日 A | 52666 | 0 | 0 | $0 |
| BAILEY MICHAEL P | 董事 | 2026年5月21日 A | 108000 | 0 | 0 | $0 |
| Robert E. Gagnon | 董事 | 2025年12月16日 S | 41678 | 0 | 2 | $-5394 |
| Lesley Kim Solomon | 董事 | 2022年5月12日 A | — | 0 | 0 | $0 |
| Bruce Wendel | 董事 | 2020年6月16日 A | — | 0 | 0 | $0 |
| Alison Frances Lawton | 董事 | 2019年6月21日 A | 2500 | 0 | 0 | $0 |
| Louise S. Phanstiel | 董事 | 2017年6月13日 A | 26500 | 0 | 0 | $0 |
| Paul A Friedman, M.D. | 董事 | 2016年6月14日 A | 3000 | 0 | 0 | $0 |
| SHERWIN STEPHEN A | 董事 | 2015年6月12日 A | 2500 | 0 | 0 | $0 |
| TERMEER HENRI A | 董事 | 2015年6月12日 A | 14000 | 0 | 0 | $0 |
| Richard Aldrich | 董事 | 2014年6月10日 A | 408142 | 0 | 0 | $0 |
| John K Clarke | 董事 | 2013年6月12日 P | 2329121 | 0 | 0 | $0 |
| Deer Management Co. LLC | 董事 | 2012年3月6日 A | — | 0 | 0 | $0 |
| Stephen Kraus | 董事 | 2012年3月6日 A | 0 | 0 | 0 | $0 |
| ANSBERT GADICKE | 董事 | 2012年3月6日 A | 3740 | 0 | 0 | $0 |
| Longwood Fund, L.P. | 10% 所有者 | 2014年1月24日 J | 1919898 | 0 | 0 | $0 |
| CHP III LP | 10% 所有者 | 2013年6月12日 P | 2329121 | 0 | 0 | $0 |
| Dan Paterson | — | 2026年8月3日 S | 589940 | 0 | 23 | $-506018 |
| Gina Consylman | — | 2021年6月28日 A | — | 0 | 0 | $0 |
| BARBERICH TIMOTHY J | — | 2021年6月28日 A | 218000 | 0 | 0 | $0 |
来自SEC表格3/4/5申报的内部人士；净额=仅公开市场买卖
激进投资者及 5%+ 股东 5 持仓
提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权，意图影响发行人（激进股东持股、董事会活动、并购）。每一行显示该申报人持仓的最新已知状态。
| 申报人 | 已申报 | 持股 | 状态 | 目的 | 申报 |
|---|---|---|---|---|---|
| DEER VII & CO. LTD., DEER VII & CO. L.P., BESSEMER VENTURE PARTNERS VII L.P., BESSEMER VENTURE PARTNERS VII INSTITUTIONAL L.P., BVP VII SPECIAL OPPORTUNITY FUND L.P., DEER MANAGEMENT CO. LLC ×4 申报 | 2014年2月25日 | — | 初始申报 | — | SEC |
| Longwood Fund, L.P. (2), Longwood Fund GP, LLC (2), Christoph Westphal, M.D., Ph.D. (2), Richard Aldrich (2), Michelle Dipp, M.D., Ph.D. (2) ×4 申报 | 2014年2月20日 | — | 初始申报 | — | SEC |
| 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人 | 2013年7月15日 | — | 初始申报 | — | SEC |
| CHP III, L.P. (2), CHP III Management, LLC (2), John K. Clarke (2), Brandon H. Hull (2), John J. Park (2), Charles G. Hadley (2) | 2012年2月13日 | — | 初始申报 | 被动投资 | SEC |
| MPM BioVentures V, L.P. (2), MPM Asset Management Investors BV5 LLC (2), MPM BioVentures V GP LLC (2), MPM BioVentures V LLC (2), Ansbert Gadicke (2), Luke Evnin (2), Steven St. Peter (2), Todd Foley (2), James Paul Scopa (2), Vaughn M. Kailian (2), John Vander Vort (2) | 2012年2月10日 | — | 初始申报 | 被动投资 | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF持仓 由 22 只交易所交易基金持有
权重仅反映直接股权持仓（N-PORT）；杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。
| 基金 | 权重 | 单位 | 截至 | 来源 |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 0.42% | 28720 NS | 2026年4月30日 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0.12% | 117456 NS | 2026年4月30日 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0.01% | 29304 NS | 2026年5月31日 | N-PORT |
| RSSL · Global X Funds | 0.01% | 29041 NS | 2026年4月30日 | N-PORT |
| ITWO · ProShares Trust | 0.01% | 3154 NS | 2026年5月31日 | N-PORT |
| UWM · ProShares Trust | 0.00% | 2466 NS | 2026年5月31日 | N-PORT |
| URTY · ProShares Trust | 0.00% | 2492 NS | 2026年5月31日 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0.00% | 2411 NS | 2026年5月31日 | N-PORT |
| HDG · ProShares Trust | 0.00% | 63 NS | 2026年5月31日 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | 2026年7月15日 | 每日 |
| VTI · VANGUARD INDEX FUNDS | — | — | 2026年7月15日 | 每日 |
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | 2026年7月15日 | 每日 |
| VTWG · VANGUARD SCOTTSDALE FUNDS | — | — | 2026年7月15日 | 每日 |
| VTHR · VANGUARD SCOTTSDALE FUNDS | — | — | 2026年7月15日 | 每日 |
| ITOT · iShares Trust | — | — | 2026年7月22日 | 每日 |
| IWV · iShares Trust | — | — | 2026年8月18日 | 每日 |
| IWO · iShares Trust | — | — | 2026年8月18日 | 每日 |
| IWM · iShares Trust | — | — | 2026年8月18日 | 每日 |
| IWC · iShares Trust | — | — | 2026年8月18日 | 每日 |
| PRFZ · Invesco Exchange-Traded Fund Trust | — | — | 2026年7月13日 | 每日 |
| VHT · VANGUARD WORLD FUND | — | — | 2026年7月20日 | 每日 |
| IDNA · iShares Trust | — | — | 2026年8月12日 | 每日 |