AGIO Agios Pharmaceuticals, Inc. - Common Stock

NASDAQ · Biotechnology · 在 SEC EDGAR 上查看 ↗
$35.43
价格 · 八月 19, 2026
截至...的财报数据 七月 30, 2026

关于 Agios Pharmaceuticals, Inc. - Common Stock 公司概况(来自维基百科)

Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.

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Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 (or 2007) by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.

History

In 2012, Agios was named among the defendants in a lawsuit against one of its founders, Craig Thompson, alleging that Thompson used research illegally taken from the Abramson Family Cancer Research Institute in research at Agios.

In May 2016, the company announced it would launch partnership with Celgene, developing metabolic immuno-oncology therapies and licensing AG-221 as well as AG-881 to Celgene, potentially garnering Agios $120 million in drug licensing payments.

In April 2017, the company raised $250 million in a new stock offering in anticipation of approval for its first cancer drug, enasidenib, by the US Food and Drug Administration.

In December 2017, the company filed a New Drug Application with the US FDA for ivosidenib for the treatment of adult patients with relapsed or refractory acute myeloid leukemia with an IDH1 mutation.

In November 2019, Agios announced an underwritten public offering of 8,250,000 shares of common stock at a price of $31.00 per share which would result in approximately $256 million aggregate gross proceeds.

In April 2022, the FDA approved mitapivat as first disease-modifying therapy for hemolytic anemia in adults with pyruvate kinase deficiency.

Corporate governance

As of August 2022, Agios' CEO is Brian Goff.

Agios was established as a private company and converted to a public company with its initial public offering in July 2013 and subsequent listing on NASDAQ.

== References ==

来源:维基百科 (英语), CC BY-SA 4.0 · 在维基百科上查看 ↗

Wikidata ↗

AGIO 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围

价格
$35.43
市值
$2.68T
P/E (TTM)
-6432.7
每股收益 (TTM)
$-7.12
营收 (TTM)
$54M
股息收益率
ROE
-32.2%
负债/权益
52周区间
$22 – $46

AGIO 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图

10年表现 收入、净利润、利润率和每股收益趋势

营收与净利润 $54M
10-point trend, -22.7%
2016-12-31 2025-12-31
EPS $-7.12
7-point trend, -3.8%
2019-12-31 2025-12-31
自由现金流 $-377M
10-point trend, -1417.0%
2016-12-31 2025-12-31
利润率 -764.0%

估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜?

指标
5年趋势
AGIO
同行中位数
P/E (TTM)
5-point trend, -408.8%
-6432.7
27.2
P/S (TTM) (市销率 (TTM))
5-point trend, +6.3%
49548.7
25.4
P/B (市净率)
5-point trend, -3.5%
2243.8
5.1
Price / FCF (股价/自由现金流)
5-point trend, +2.5%
-7095.3

盈利能力 毛利率、营业利润率和净利率;股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)

指标
5年趋势
AGIO
同行中位数
Operating Margin (营业利润率)
5-point trend, -461.6%
-873.9%
Net Profit Margin (净利润率)
5-point trend, -374.2%
-764.0%
-473.7%
ROA
5-point trend, -119.9%
-27.9%
-40.2%
ROE
5-point trend, -127.0%
-32.2%
-50.4%
ROIC
5-point trend, +53.8%
-39.5%

财务健康 债务、流动性、偿付能力 — 资产负债表强度

指标
5年趋势
AGIO
同行中位数
Current Ratio (流动比率)
5-point trend, -35.6%
11.5
9.0
Quick Ratio (速动比率)
5-point trend, -68.1%
1.1

成长 营收、每股收益 (EPS) 和净利润增长:同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)

指标
5年趋势
AGIO
同行中位数
Revenue YoY (营收同比增长)
5-point trend, +54028000.00
48.0%
Revenue CAGR 3Y (营收3年复合年增长率)
5-point trend, +54028000.00
56.0%

每股指标 每股收益 (EPS)、每股净资产、每股现金流、每股股息

指标
5年趋势
AGIO
同行中位数
EPS (Diluted) (EPS (稀释))
5-point trend, -126.8%
$-7.12

资本效率 资产周转率、库存周转率、应收账款周转率

指标
5年趋势
AGIO
同行中位数

AGIO 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间

买入 16 位分析师
  • 强烈买入 5 31.2%
  • 买入 7 43.8%
  • 持有 4 25.0%
  • 卖出 0 0.0%
  • 强烈卖出 0 0.0%

12个月价格目标

8 位分析师 · 2026-08-16
中位数目标 $42.50 +20.0%
平均目标 $45.75 +29.1%

收益历史 每股收益实际值 vs 预估值,惊喜%,达标率,下次财报日期

平均惊喜
0.10%
期间 EPS Actual EPS 预期 惊喜
2026年6月30日 $-1.69 $-1.70 0.01%
2026年3月31日 $-1.69 $-1.84 0.15%
2025年12月31日 $-1.86 $-1.99 0.13%
2025年9月30日 $-1.78 $-1.94 0.16%
2025年6月30日 $-1.93 $-1.84 -0.09%
2025年3月31日 $-1.55 $-1.82 0.27%

同行比较(GICS 子行业) 关键指标与行业同行对比

股票代码 市值 P/E 营收同比增长 净利润率 ROE 毛利率
AGIO $1.59B -3.8 48.0% -764.0% -32.2%
ADMA $4.34B 30.4 19.6% 28.8% 33.6% 57.4%
VRDN $3.17B -7.7 23359.9% -483.6% -55.4%
STOK $1.87B -264.5 404.5% -3.7% -2.0%
ZBIO $1.98B -4.3 100.0% -3777.4% -156.8%
TSHA $1.57B -16.2 17.3% -1115.3% -44.0%
GENB
DMRA 38.3% -17981.1% -167.0%
SRPT $2.26B -3.0 15.6% -32.5% -57.1%
SNDX $1.84B -6.4 627.8% -165.6% -257.1%

完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表

损益表 16
AGIO 的年度损益表数据
指标 趋势 202520242023202220212020201920182017201620152014
Revenue 12-point trend, -17.3% $54M $36M $27M $14M $0 $0 $118M $94M $43M $70M $59M $65M
Cost of Revenue 10-point trend, +6345000.00 $6M $4M $3M $2M $0 $0 $1M $1M $0 $0 · ·
R&D Expense 12-point trend, +238.3% $340M $301M $296M $280M $257M $221M $214M $341M $293M $220M $142M $100M
SG&A Expense 12-point trend, +842.9% $180M $157M $120M $122M $121M $115M $102M $114M $71M $51M $36M $19M
Operating Expenses 12-point trend, +340.3% $526M $462M $418M $403M $378M $336M $316M $457M $364M $271M $178M $119M
Operating Income 12-point trend, -772.2% $-472M $-426M $-391M $-389M $-378M $-336M $-316M $-362M $-321M $-201M $-119M $-54M
Interest Income 9-point trend, +6202.0% · · · $13M $836.0K $7M $15M $16M $6M $3M $968.0K $203.0K
Other Non-op 7-point trend, +1956000.00 $2M $6M $6M $7M $14M $0 $0 · · · · ·
Pretax Income 12-point trend, -667.3% $-414M $718M $-352M $-232M $-357M $-329M $-301M $-346M $-315M $-198M $-118M $-54M
Income Tax 10-point trend, -138.5% $-1M $44M $0 $0 · · $0 $0 $0 $0 $0 $-426.0K
Net Income 12-point trend, -671.5% $-413M $674M $-352M $-232M $1.60B $-327M $-411M $-346M $-315M $-198M $-118M $-54M
EPS (Basic) 7-point trend, -3.8% $-7.12 $11.86 $-6.33 $-4.23 $26.55 $-4.74 $-6.86 · · · · ·
EPS (Diluted) 7-point trend, -3.8% $-7.12 $11.64 $-6.33 $-4.23 $26.55 $-4.74 $-6.86 · · · · ·
Shares (Basic) 7-point trend, -3.4% 57,972,004 56,807,415 55,651,487 54,789,435 60,447,346 68,997,879 59,994,539 · · · · ·
Shares (Diluted) 7-point trend, -3.4% 57,972,004 57,889,255 55,651,487 54,789,435 60,447,346 68,997,879 59,994,539 · · · · ·
EBITDA 12-point trend, -772.2% $-472M $-426M $-391M $-389M $-378M $-316M $-418M $-362M $-321M $-201M $-119M $-54M
资产负债表 22
AGIO 的年度资产负债表数据
指标 趋势 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +535.2% $89M $76M $88M $139M $203M $127M $81M $71M $103M $161M $72M $14M
Short-term Investments 3-point trend, +35.3% · · · · · · · $515M $321M $381M · ·
Inventory 9-point trend, +32920000.00 $33M $28M $19M $8M $0 $15M $7M $869.0K $0 · · ·
Prepaid Expense 12-point trend, +816.7% $44M $40M $35M $39M $40M $16M $24M $17M $18M $10M $9M $5M
Current Assets 12-point trend, +162.0% $942M $966M $834M $833M $1.06B $637M $612M $614M $445M $560M $337M $360M
PP&E (Net) 12-point trend, +68.7% $11M $12M $15M $23M $29M $31M $31M $24M $24M $25M $23M $6M
PP&E (Gross) 12-point trend, +493.5% $71M $68M $68M $73M $74M $72M $64M $50M $44M $39M $31M $12M
Accum. Depreciation 12-point trend, +981.6% $60M $56M $52M $50M $45M $41M $32M $26M $19M $13M $8M $6M
Other Non-current Assets 12-point trend, +566.3% $4M $5M $4M $4M $3M $0 $0 $238.0K $891.0K $2M $611.0K $590.0K
Total Assets 12-point trend, +163.7% $1.30B $1.66B $937M $1.24B $1.44B $853M $891M $858M $614M $619M $420M $492M
Accounts Payable 12-point trend, +65.9% $18M $17M $10M $19M $17M $18M $22M $18M $23M $17M $15M $11M
Accrued Liabilities 12-point trend, +224.2% $45M $47M $43M $30M $32M $31M $53M $42M $34M $32M $16M $14M
Current Liabilities 12-point trend, +34.6% $82M $81M $68M $63M $60M $94M $93M $94M $95M $88M $53M $61M
Capital Leases 7-point trend, -79.4% $22M $40M $57M $72M $86M $97M $106M · · · · ·
Other Non-current Liabilities 5-point trend, +90000.00 $90.0K $880.0K $1M $3M $0 · · · · · · ·
Total Liabilities 10-point trend, -60.0% $104M $122M $126M $138M $146M $453M $250M $171M $239M $261M · ·
Common Stock 8-point trend, +91.9% · · · · $71.0K $69.0K $68.0K $58.0K $49.0K $42.0K $38.0K $37.0K
Retained Earnings 12-point trend, -236.5% $-562M $-149M $-823M $-471M $-239M $-1.84B $-1.52B $-1.10B $-798M $-483M $-285M $-167M
Treasury Stock 6-point trend, +802486000.00 $802M $802M $802M $802M $802M $0 · · · · · ·
Stockholders' Equity 12-point trend, +181.2% $1.19B $1.54B $811M $1.10B $1.29B $400M $641M $688M $376M $359M $345M $424M
Liabilities + Equity 12-point trend, +163.7% $1.30B $1.66B $937M $1.24B $1.44B $853M $891M $858M $614M $619M $420M $492M
Shares Outstanding 12-point trend, +57.5% 58,448,592 73,372,696,000 72,161,489 71,256,118 70,550,631 69,293,920 68,401,105 58,218,653 48,826,153 42,220,444 37,696,502 37,100,513
现金流 13
AGIO 的年度现金流数据
指标 趋势 202520242023202220212020201920182017201620152014
D&A 3-point trend, +25.7% · · · · · · $8M $7M $6M · · ·
Stock-based Comp 12-point trend, +356.7% $53M $43M $45M $49M $54M $62M $58M $73M $48M $42M $32M $12M
Deferred Tax Flat — no change across 3 periods · · · · · · · · · $0 $0 $0
Other Non-cash · · · · · · $-40M · · · · ·
Operating Cash Flow 12-point trend, -528.4% $-373M $-390M $-296M $-309M $-407M $-291M $-371M $-304M $-285M $39M $-77M $-59M
CapEx 12-point trend, +94.8% $4M $2M $999.0K $5M $6M $14M $12M $7M $5M $10M $20M $2M
Investing Cash Flow 11-point trend, +194.0% $377M $363M $240M $243M $1.25B $76M $91M $-274M $-58M $-119M $128M ·
Stock Issued 8-point trend, -100.0% · · · · $0 $0 $277M $516M $270M $162M $0 $334M
Net Stock Activity 7-point trend, -100.0% · · · · $0 $0 $277M $516M $270M $162M · $334M
Financing Cash Flow 11-point trend, +36.1% $9M $14M $5M $2M $-766M $262M $290M $546M $285M $170M $6M ·
Net Change in Cash 12-point trend, +122.4% $13M $-12M $-51M $-64M $76M $47M $10M $-32M $-58M $89M $58M $-58M
Taxes Paid 3-point trend, -60.0% $628.0K $43M $2M · · · · · · · · ·
Free Cash Flow 12-point trend, -512.8% $-377M $-392M $-297M $-314M $-413M $-306M $-383M $-311M $-290M $29M $-97M $-62M
盈利能力 7
AGIO 的年度盈利能力数据
指标 趋势 202520242023202220212020201920182017201620152014
Operating Margin 8-point trend, -955.0% -873.9% -1166.5% -1459.5% -2732.1% · -155.6% -361.6% · -745.8% · · -82.8%
Net Margin 8-point trend, -833.3% -764.0% 1845.9% -1312.6% -1627.8% · -161.1% -349.0% · -731.6% · · -81.9%
Pretax Margin 8-point trend, -828.2% -765.9% 1967.2% -1312.6% -1627.8% · -161.2% -349.0% · -731.6% · · -82.5%
EBITDA Margin 8-point trend, -955.0% -873.9% -1166.5% -1459.5% -2732.1% · -155.6% -354.7% · -745.8% · · -82.8%
ROA 12-point trend, -80.6% -27.9% 51.8% -32.4% -17.3% 140.1% -37.5% -47.0% -47.0% -51.0% -38.2% -25.8% -15.4%
ROE 12-point trend, -67.3% -32.2% 42.5% -41.5% -21.6% 119.4% -74.4% -75.6% -47.8% -85.7% -56.4% -30.6% -19.2%
ROIC 6-point trend, -211.8% -39.5% -25.9% · · · · -66.6% -52.7% -85.4% · · -12.7%
流动性与偿付能力 2
AGIO 的年度流动性与偿付能力数据
指标 趋势 202520242023202220212020201920182017201620152014
Current Ratio 12-point trend, +94.7% 11.5 11.9 12.3 13.3 17.8 6.7 6.6 6.6 4.7 6.3 6.4 5.9
Quick Ratio 12-point trend, +372.0% 1.1 0.9 1.3 2.2 3.4 1.4 0.9 6.3 4.5 1.8 1.4 0.2
效率 2
AGIO 的年度效率数据
指标 趋势 202520242023202220212020201920182017201620152014
Asset Turnover 8-point trend, -80.6% 0.0 0.0 0.0 0.0 · 0.2 0.1 · 0.1 · · 0.2
Inventory Turnover 7-point trend, -93.5% 0.2 0.2 0.2 0.4 · 0.3 0.3 3.2 · · · ·
每股 5
AGIO 的年度每股数据
指标 趋势 202520242023202220212020201920182017201620152014
Book Value / Share 12-point trend, +78.5% $20.41 $26.96 $14.50 $20.00 $23.78 $5.77 $9.36 $11.81 $7.69 $8.49 $9.16 $11.44
Revenue / Share 4-point trend, +258.6% $0.93 $0.63 $0.48 $0.26 · · · · · · · ·
Cash Flow / Share 5-point trend, +4.5% $-6.43 $-6.73 $-5.32 $-5.65 $-6.74 · · · · · · ·
Cash / Share 12-point trend, +303.2% $1.52 $1.33 $1.58 $2.53 $3.74 $1.84 $1.18 $1.21 $2.10 $3.81 $1.90 $0.38
EPS (TTM) 8-point trend, -347.8% $-7.12 $11.64 $-6.33 $-4.23 $26.55 $-4.74 $-6.86 · · · · $-1.59
增长率 4
AGIO 的年度增长率数据
指标 趋势 202520242023202220212020201920182017201620152014
Revenue YoY 3-point trend, -45.6% 48.0% 36.1% 88.4% · · · · · · · · ·
Revenue CAGR 3Y 56.0% · · · · · · · · · · ·
EPS CAGR 3Y · -24.0% · · · · · · · · · ·
Net Income CAGR 3Y · -25.1% · · · · · · · · · ·
估值 (TTM) 10
AGIO 的年度估值 (TTM)数据
指标 趋势 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, -17.3% $54M $36M $27M $14M $0 $0 $118M $94M $43M $70M $59M $65M
Net Income TTM 12-point trend, -671.5% $-413M $674M $-352M $-232M $1.60B $-327M $-411M $-346M $-315M $-198M $-118M $-54M
Market Cap 12-point trend, -61.7% $1.59B $1.88B $1.25B $1.55B $1.79B $3.00B $3.27B $2.68B $2.79B $1.76B $2.45B $4.16B
P/E 8-point trend, +94.6% -3.8 2.8 -3.5 -6.6 1.2 -9.1 -7.0 · · · · -70.5
P/S 10-point trend, -53.7% 29.4 51.5 46.4 108.5 · · 27.7 28.4 64.9 25.2 41.4 63.6
P/B 12-point trend, -86.4% 1.3 1.2 1.5 1.4 1.4 7.5 5.1 3.9 7.4 4.9 7.1 9.8
P / Tangible Book 6-point trend, -82.3% 1.3 1.2 1.5 1.4 1.4 7.5 · · · · · ·
P / Cash Flow 12-point trend, +93.9% -4.3 -4.8 -4.2 -5.0 -4.4 -10.3 -8.8 -8.8 -9.8 45.7 -31.8 -70.0
P / FCF 12-point trend, +93.8% -4.2 -4.8 -4.2 -4.9 -4.3 -9.8 -8.5 -8.6 -9.6 61.5 -25.2 -67.5
Earnings Yield 8-point trend, -1742.3% -26.2% 35.4% -28.4% -15.1% 80.8% -10.9% -14.4% · · · · -1.4%

财务报表 损益表、资产负债表、现金流量表 — 年度,近5年

损益表
2025-12-312024-12-312023-12-312022-12-312021-12-31
收入 $54M$36M$27M$14M$0
营业利润率 % -873.9%-1166.5%-1459.5%-2732.1%
净收入 $-413M$674M$-352M$-232M$1.60B
稀释后每股收益 (EPS) $-7.12$11.64$-6.33$-4.23$26.55
资产负债表
2025-12-312024-12-312023-12-312022-12-312021-12-31
流动比率 11.511.912.313.317.8
速动比率 1.10.91.32.23.4
现金流
2025-12-312024-12-312023-12-312022-12-312021-12-31
自由现金流 $-377M$-392M$-297M$-314M$-413M

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机构持有人 (13F) 264 家申报者 · $2.0B 总计 · 截至 2026年6月30日

在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸;单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存,而非方向性判断。

机构活动 — Q2 2026 与上一季度对比
新仓位 已退出持仓 增加 减少 净股数变动
46 (+12 与上一季度对比) 30 (-3 与上一季度对比) 95 (+17 与上一季度对比) 62 (-27 与上一季度对比) +12.7M

与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天,外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过,优先显示最近一个已完整报告的季度对。

机构 价值 股份 % 已追踪的13F 类型
FARALLON CAPITAL MANAGEMENT, L.L.C. $219594714 5917400 11.17% 股份
STATE STREET CORP $131144972 3533633 6.67% 股份
Lynx1 Capital Management LP $126505652 3408937 6.43% 股份
VANGUARD PORTFOLIO MANAGEMENT LLC $107552091 2898197 5.47% 股份
ARMISTICE CAPITAL, LLC $104279100 2810000 5.30% 买入期权
VANGUARD CAPITAL MANAGEMENT LLC $99523268 2681845 5.06% 股份
ARMISTICE CAPITAL, LLC $89064000 2400000 4.53% 股份
Erste Asset Management GmbH $81972396 2154900 4.17% 股份
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $78332000 2110809 3.98% 股份
SUSQUEHANNA INTERNATIONAL GROUP, LLP $51046957 1375558 2.60% 股份
GEODE CAPITAL MANAGEMENT, LLC $50151466 1351093 2.55% 股份
ADAR1 Capital Management, LLC $47799647 1288053 2.43% 股份
DIMENSIONAL FUND ADVISORS LP $44225805 1191749 2.25% 股份
GOLDMAN SACHS GROUP INC $36642971 987415 1.86% 股份
D. E. Shaw & Co., Inc. $34087168 918544 1.73% 股份
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $30078768 810530 1.53% 股份
Foresite Capital Management VI LLC $29131350 785000 1.48% 股份
CITADEL ADVISORS LLC $26154683 704788 1.33% 股份
Parkman Healthcare Partners LLC $24828297 669046 1.26% 股份
SCS Capital Management LLC $22742864 612850 1.16% 股份
Qube Research & Technologies Ltd $22178346 597638 1.13% 股份
Defilade Capital Management, L.P. $20293529 546848 1.03% 股份
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $19969930 538128 1.02% 股份
TWO SIGMA INVESTMENTS, LP $19905062 536380 1.01% 股份
Rock Springs Capital Management LP $19763413 532563 1.01% 股份
Schonfeld Strategic Advisors LLC $19300279 520083 0.98% 股份
Point72 Asset Management, L.P. $18790426 506344 0.96% 股份
JANE STREET GROUP, LLC $18280312 492598 0.93% 股份
VANGUARD FIDUCIARY TRUST CO $14690661 395868 0.75% 股份
PANAGORA ASSET MANAGEMENT INC $13876579 373931 0.71% 股份
KENNEDY CAPITAL MANAGEMENT LLC $13850565 373230 0.70% 股份
Connor, Clark & Lunn Investment Management Ltd. $13342901 359550 0.68% 股份
Squarepoint Ops LLC $11917431 321138 0.61% 股份
JPMORGAN CHASE & CO $11853074 309008 0.60% 股份
Ensign Peak Advisors, Inc $11045049 297630 0.56% 股份
BNP PARIBAS FINANCIAL MARKETS $9996803 269383 0.51% 股份
ALGERT GLOBAL LLC $9203540 248007 0.47% 股份
JANE STREET GROUP, LLC $7974939 214900 0.41% 卖出期权
Palo Alto Investors LP $7926733 213601 0.40% 股份
Tetragon Partners GP Ltd $7629037 205579 0.39% 股份
AXA Investment Managers S.A. $7131875 177675 0.36% 股份
Cutter Capital Management, LP $6895755 235350 0.35% 股份
BlackRock, Inc. $6545388 176378 0.33% 股份
SUSQUEHANNA INTERNATIONAL GROUP, LLP $6334677 170700 0.32% 买入期权
BNP PARIBAS ASSET MANAGEMENT Holding S.A. $6306139 169931 0.32% 股份
FIRST TRUST ADVISORS LP $6144933 165587 0.31% 股份
Ishara Investments LP $6086040 164000 0.31% 股份
GROUP ONE TRADING LLC $5640497 151994 0.29% 股份
BOOTHBAY FUND MANAGEMENT, LLC $5562269 149886 0.28% 股份
BANK OF AMERICA CORP /DE/ $5505083 148345 0.28% 股份
MARSHALL WACE, LLP $5150868 138800 0.26% 股份
SUSQUEHANNA INTERNATIONAL GROUP, LLP $5080359 136900 0.26% 卖出期权
AMERICAN CENTURY COMPANIES INC $4991740 134512 0.25% 股份
Man Group plc $4617931 124439 0.23% 股份
ArrowMark Colorado Holdings LLC $4368367 117714 0.22% 股份
Pictet Asset Management Holding SA $4247606 111861 0.22% 股份
Swiss National Bank $4143703 111660 0.21% 股份
CAPITAL FUND MANAGEMENT S.A. $3862408 104080 0.20% 股份
Assenagon Asset Management S.A. $3857770 103955 0.20% 股份
Universal- Beteiligungs- und Servicegesellschaft mbH $3700831 99726 0.19% 股份
Knott David M Jr $3527602 95058 0.18% 股份
Trexquant Investment LP $3471232 93539 0.18% 股份
CITADEL ADVISORS LLC $3402987 91700 0.17% 买入期权
Jain Global LLC $3401020 91647 0.17% 股份
Caligan Partners LP $3339900 90000 0.17% 买入期权
CITADEL ADVISORS LLC $3295368 88800 0.17% 卖出期权
CITIGROUP INC $3182331 85754 0.16% 股份
RHUMBLINE ADVISERS $2948045 79441 0.15% 股份
Bank of New York Mellon Corp $2916846 78600 0.15% 股份
Campbell & CO Investment Adviser LLC $2712555 73095 0.14% 股份
Exome Asset Management LLC $2616255 70500 0.13% 股份
Edgestream Partners, L.P. $2604936 70195 0.13% 股份
TUDOR INVESTMENT CORP ET AL $2441059 65779 0.12% 股份
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $2319520 68564 0.12% 股份
TWO SIGMA ADVISERS, LP $2319144 85200 0.12% 股份
ALPS ADVISORS INC $2228789 60059 0.11% 股份
Seven Fleet Capital Management LP $2111559 56900 0.11% 股份
ALLIANCEBERNSTEIN L.P. $2092859 61864 0.11% 股份
Rafferty Asset Management, LLC $2062574 55580 0.10% 股份
Engineers Gate Manager LP $2000674 53912 0.10% 股份
WELLS FARGO & COMPANY/MN $1935843 52165 0.10% 股份
VANGUARD ASSET MANAGEMENT, Ltd $1931576 52050 0.10% 股份
XTX Topco Ltd $1869082 50366 0.10% 股份
Caption Management, LLC $1855500 50000 0.09% 买入期权
Tetragon Partners GP Ltd $1855500 50000 0.09% 买入期权
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main $1846742 49764 0.09% 股份
BARCLAYS PLC $1725651 46501 0.09% 股份
Quantinno Capital Management LP $1614805 43514 0.08% 股份
MARTINGALE ASSET MANAGEMENT L P $1596064 43009 0.08% 股份
IEQ CAPITAL, LLC $1499392 40404 0.08% 股份
Kodai Capital Management LP $1485276 50692 0.08% 股份
Virtus Investment Advisers, LLC $1464843 39473 0.07% 股份
Caption Management, LLC $1456530 39249 0.07% 股份
JANE STREET GROUP, LLC $1451001 39100 0.07% 买入期权
FMR LLC $1446325 38974 0.07% 股份
Aquatic Capital Management LLC $1433448 38627 0.07% 股份
MANUFACTURERS LIFE INSURANCE COMPANY, THE $1400049 37727 0.07% 股份
VANGUARD GROUP INC $1308928 48087 0.07% 股份
EDGEWOOD MANAGEMENT LLC $1298850 35000 0.07% 股份
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $1298776 34998 0.07% 股份

公司内部人士 33 位内幕人士 · 12 位高管 · 19 位董事

内部人士 角色 上次活动 持股数量 买入 12个月 卖出 12个月 净额 12个月
Brian Goff Chief Executive Officer 2026年6月18日 A 0 0 $0
Cecilia Jones Chief Financial Officer 2026年6月18日 A 0 0 $0
Andrew Hirsch Chief Financial Officer 2019年4月22日 A 12374 0 0 $0
John Duncan Higgons Chief Operating Officer 2016年1月4日 M 120834 0 0 $0
Krishnan Viswanadhan Chief Strategy and Operations 2026年6月18日 A 0 0 $0
Tsveta Milanova Chief Commercial Officer 2026年6月18日 A 0 0 $0
James William Burns Chief Legal Officer 2026年6月18日 A 0 0 $0
Scott Biller Chief Scientific Officer 2019年4月5日 M 26511 0 0 $0
Christopher Bowden Chief Medical Officer 2019年4月1日 M 7238 0 0 $0
Steven L. Hoerter Chief Commercial Officer 2019年3月4日 M 10941 0 0 $0
Carman Alenson Principal Accounting Officer 2019年2月22日 A 2796 0 0 $0
Glenn Goddard Senior Vice President, Finance 2016年2月16日 A 0 0 0 $0
Adams Catherine Owen 董事 2026年6月18日 A 10865 0 0 $0
Rahul D. Ballal 董事 2026年6月18日 A 15230 0 0 $0
David Scadden 董事 2026年6月18日 A 20419 0 0 $0
Maykin Ho 董事 2026年6月18日 A 19848 0 0 $0
Cynthia Smith 董事 2026年6月18日 A 15230 0 0 $0
Jacqualyn A Fouse 董事 2026年6月18日 A 154156 0 0 $0
Kaye I Foster-Cheek 董事 2026年6月18日 A 10284 0 0 $0
Jeffrey D Capello 董事 2026年6月18日 A 10865 0 0 $0
Paul J Clancy 董事 2019年5月31日 M 1400 0 0 $0
Ian T Clark 董事 2019年5月31日 M 1400 0 0 $0
John Maraganore 董事 2019年5月31日 M 37609 0 0 $0
David P Schenkein 董事 2019年2月22日 A 89503 0 0 $0
Lewis Clayton Cantley Jr. 董事 2017年12月7日 S 79515 0 0 $0
Robert Nelsen 董事 2017年3月6日 S 0 0 0 $0
Douglas G. Cole 董事 2016年8月10日 J 2778 0 0 $0
Marc Tessier-Lavigne 董事 2016年6月21日 A 101009 0 0 $0
Perry A Karsen 董事 2015年6月23日 A 0 0 $0
Kevin P Starr 董事 2015年2月19日 J 184386 0 0 $0
Celgene European Investment Co LLC 10% 所有者 2014年12月16日 P 1231778 0 0 $0
Sarah Gheuens 2026年8月4日 S 54645 0 2 $-1064903
Jay T. Backstrom 2026年7月8日 M 1447 0 0 $0

来自SEC表格3/4/5申报的内部人士;净额=仅公开市场买卖

激进投资者及 5%+ 股东 3 持仓

提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权,意图影响发行人(激进股东持股、董事会活动、并购)。每一行显示该申报人持仓的最新已知状态。

申报人 已申报 持股 状态 目的 申报
BRISTOL-MYERS SQUIBB COMPANY, CELGENE CORPORATION, CELGENE SWITZERLAND LLC, CELGENE EUROPEAN INVESTMENT COMPANY LLC, CELGENE ALPINE INVESTMENT CO., LLC 2021年4月5日 初始申报 SEC
CELGENE SWITZERLAND LLC, CELGENE EUROPEAN INVESTMENT COMPANY LLC, CELGENE ALPINE INVESTMENT CO., LLC, CELGENE CORPORATION ×3 申报 2019年11月14日 初始申报 资本结构 SEC
CELGENE EUROPEAN INVESTMENT COMPANY LLC, CELGENE ALPINE INVESTMENT CO., LLC, CELGENE CORPORATION ×3 申报 2014年12月17日 初始申报 资本结构 SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF持仓 由 57 只交易所交易基金持有

权重仅反映直接股权持仓(N-PORT);杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。

基金 权重 单位 截至 来源
BBP · ETFis Series Trust I 1.64% 34703 NS 2026年4月30日 N-PORT
SBIO · ALPS ETF Trust 1.10% 60392 NS 2026年5月31日 N-PORT
HAPS · Harbor ETF Trust 0.77% 43269 NS 2026年4月30日 N-PORT
LABU · Direxion Shares ETF Trust 0.60% 110585 NS 2026年4月30日 N-PORT
QQQS · Invesco Exchange-Traded Fund Trus... 0.54% 3805 SH 2026年8月8日 每日
AGNG · Global X Funds 0.28% 7695 NS 2026年5月31日 N-PORT
FYC · First Trust Exchange-Traded Alpha... 0.27% 101599 NS 2026年4月30日 N-PORT
OMFS · Invesco Exchange-Traded Self-Inde... 0.19% 17290 SH 2026年8月8日 每日
IBB · iShares Trust 0.14% 408719 SH 2026年8月8日 每日
IBBQ · Invesco Exchange-Traded Fund Trus... 0.13% 3239 SH 2026年8月8日 每日
VTWV · VANGUARD SCOTTSDALE FUNDS 0.13% 48730 SH 2026年8月8日 每日
PRFZ · Invesco Exchange-Traded Fund Trust 0.13% 113617 SH 2026年8月8日 每日
AVSC · AMERICAN CENTURY ETF TRUST 0.12% 109727 NS 2026年5月31日 N-PORT
IWN · iShares Trust 0.11% 515162 SH 2026年8月8日 每日
FYX · First Trust Exchange-Traded Alpha... 0.09% 40934 NS 2026年4月30日 N-PORT
BIB · ProShares Trust 0.09% 2166 NS 2026年5月31日 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund ... 0.08% 22172 NS 2026年4月30日 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.07% 340226 SH 2026年8月8日 每日
VBK · VANGUARD INDEX FUNDS 0.06% 788655 SH 2026年8月8日 每日
IWM · iShares Trust 0.06% 1508427 SH 2026年8月8日 每日
FAD · First Trust Exchange-Traded Alpha... 0.06% 9472 NS 2026年4月30日 N-PORT
ESML · iShares Trust 0.05% 48207 SH 2026年8月8日 每日
RSSL · Global X Funds 0.05% 24449 NS 2026年4月30日 N-PORT
ITWO · ProShares Trust 0.04% 2658 NS 2026年5月31日 N-PORT
DFAS · Dimensional ETF Trust 0.04% 193306 NS 2026年4月30日 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.04% 280734 NS 2026年5月31日 N-PORT
ISCG · iShares Trust 0.03% 10195 SH 2026年8月8日 每日
VB · VANGUARD INDEX FUNDS 0.03% 1364364 SH 2026年8月8日 每日
VHT · VANGUARD WORLD FUND 0.03% 167169 SH 2026年8月8日 每日
ISCB · iShares Trust 0.03% 2463 SH 2026年8月8日 每日
FHLC · FIDELITY COVINGTON TRUST 0.02% 25231 NS 2026年4月30日 N-PORT
UWM · ProShares Trust 0.02% 2079 NS 2026年5月31日 N-PORT
ISCV · iShares Trust 0.02% 5020 SH 2026年8月8日 每日
VXF · VANGUARD INDEX FUNDS 0.02% 683802 SH 2026年8月8日 每日
DXUV · Dimensional ETF Trust 0.02% 2762 NS 2026年4月30日 N-PORT
URTY · ProShares Trust 0.02% 2105 NS 2026年5月31日 N-PORT
GSSC · Goldman Sachs ETF Trust 0.02% 5903 NS 2026年5月31日 N-PORT
WSML · iShares Trust 0.02% 3329 SH 2026年8月8日 每日
VTWG · VANGUARD SCOTTSDALE FUNDS 0.01% 3639 SH 2026年8月8日 每日
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.01% 2328 NS 2026年5月31日 N-PORT
DFAC · Dimensional ETF Trust 0.01% 136570 NS 2026年4月30日 N-PORT
DCOR · Dimensional ETF Trust 0.01% 8867 NS 2026年4月30日 N-PORT
HDG · ProShares Trust 0.01% 53 NS 2026年5月31日 N-PORT
ONEQ · Fidelity Commonwealth Trust 0.01% 25095 NS 2026年5月31日 N-PORT
IWO · iShares Trust 0.01% 30958 SH 2026年8月8日 每日
AVSU · AMERICAN CENTURY ETF TRUST 0.01% 1068 NS 2026年5月31日 N-PORT
TILT · FlexShares Trust 0.01% 4329 NS 2026年4月30日 N-PORT
DFAU · Dimensional ETF Trust 0.00% 17627 NS 2026年4月30日 N-PORT
DFUS · Dimensional ETF Trust 0.00% 19324 NS 2026年4月30日 N-PORT
IWV · iShares Trust 0.00% 16536 SH 2026年8月8日 每日