Palo Alto Investors LP
CIK 1306923 · 在 SEC EDGAR 上查看 ↗
- 投资组合价值
- $723.7M
- 持仓
- 52
- 截至
- 2026年6月30日
按 13F 价值排名第 3025（共 9443） · 前 32.0%
投资组合价值同比（季度）：+10.7% 13F不披露现金
- 前十大持仓权重
- 61.28%
- 前二十五大持仓权重
- 91.65%
- 持仓高于 1%
- 26
- 有效持仓数量
- 20.4
仅基于13F多头股票持仓（现金、债券、空头未披露）
周转率 Q2 2026: 4.79% 估计买入 $32983630 · 卖出 $38290648
中位数持有期：5.0 季度 跟踪时间 Q4 2024–Q2 2026 · 72.2% 仍持有
- 新仓位
- 3
- 增加
- 5
- 减少
- 15
- 已结清
- 2
本页内容
与标普500指数的表现对比
年化：+31.3% · 标普500指数：+18.0%
近似于基于季度SEC 13F快照构建的买入并持有投资组合。不包括现金、空头头寸、期权/衍生品和非13(f)证券——仅反映已披露的多头股票账簿，而非基金总资产管理规模。SEC文件延迟最多可达45天；这不是一个可实时复制的交易。
可定价覆盖率：98.9% · 已排除期权：0.0%
行业细分
Healthcare
98.0%
Financials
0.3%
其他/未映射
1.7%
完整投资组合 52 持仓
| 类型 | 连胜 | 8个季度趋势 | |||||
|---|---|---|---|---|---|---|---|
| PTCT PTC Therapeutics, Inc. - Common Stock | $74950268 | 10.36% | 918846 | $12161183 | 下跌 ×1 | ||
| ACAD ACADIA Pharmaceuticals Inc. - Common Stock | $72461629 | 10.01% | 2864096 | $8515438 | 下跌 ×1 | ||
| INSM Insmed Incorporated - Common Stock | $44138548 | 6.10% | 413980 | $-23766239 | 下跌 ×6 | ||
| MIRM Mirum Pharmaceuticals, Inc. - common stock | $40834953 | 5.64% | 348808 | $10795286 | 上涨 ×3 | ||
| ANAB AnaptysBio, Inc. - Common Stock | $40735508 | 5.63% | 603489 | $5343099 | 下跌 ×2 | ||
| BMRN BioMarin Pharmaceutical Inc. - Common Stock | $39068500 | 5.40% | 682777 | $362569 | 下跌 ×6 | ||
| DYN Dyne Therapeutics, Inc. - Common Stock | $36591441 | 5.06% | 1647521 | $6623059 | 下跌 ×1 | ||
| UTHR United Therapeutics Corporation - Common Stock | $33911514 | 4.69% | 62587 | $-3332967 | 下跌 ×1 | ||
| IRON Disc Medicine, Inc. - Common Stock | $30473488 | 4.21% | 416646 | $4787575 | 上涨 ×4 | ||
| BIIB Biogen Inc. - Common Stock | $30308681 | 4.19% | 140279 | $4510667 | 下跌 ×4 | ||
| IOVA Iovance Biotherapeutics, Inc. - Common Stock | $22032229 | 3.04% | 5296209 | $-254737 | 下跌 ×3 | ||
| RARE Ultragenyx Pharmaceutical Inc. - Common Stock | $19916968 | 2.75% | 596495 | $7420398 | |||
| NVCR NovoCure Limited - Ordinary Shares | $19398651 | 2.68% | 1280439 | $5441866 | |||
| SNDX Syndax Pharmaceuticals, Inc. - Common Stock | $18908594 | 2.61% | 864986 | $-1297479 | |||
| ANNX Annexon, Inc. - common stock | $16833594 | 2.33% | 2948090 | $501175 | |||
| BCAX Bicara Therapeutics Inc. - Common Stock | $16341614 | 2.26% | 550408 | $5393999 | |||
| CDNA CareDx, Inc. - Common Stock | $15158295 | 2.09% | 531870 | $5925032 | |||
| CLDX Celldex Therapeutics, Inc. - Common Stock | $14878642 | 2.06% | 399856 | $5476580 | 上涨 ×1 | ||
| CMPX Compass Therapeutics, Inc. - Common Stock | $12771670 | 1.76% | 5831813 | $4759944 | 上涨 ×1 | ||
| ALKS Alkermes plc - Ordinary Shares | $12708931 | 1.76% | 242560 | $4132009 | |||
| 未知发行人 (CUSIP: 337185102) | $12142199 | 1.68% | 603489 | 上涨 ×1 | |||
| PRTA Prothena Corporation plc - Ordinary Shares | $11191487 | 1.55% | 1143155 | $-555794 | 下跌 ×3 | ||
| TVTX Travere Therapeutics, Inc. - Common Stock | $9517095 | 1.32% | 167525 | $2670336 | 下跌 ×1 | ||
| TSHA Taysha Gene Therapies, Inc. - Common Stock | $9475311 | 1.31% | 1391382 | $3255833 | |||
| ACRS Aclaris Therapeutics, Inc. - Common Stock | $8535045 | 1.18% | 1613430 | $2484682 | |||
| AGIO Agios Pharmaceuticals, Inc. - Common Stock | $7926733 | 1.10% | 213601 | $700611 | |||
| CAPR Capricor Therapeutics, Inc. - Common Stock | $5532693 | 0.76% | 229763 | $-1452102 | |||
| ALGN Align Technology, Inc. - Common Stock | $5294069 | 0.73% | 31389 | $-1823705 | 下跌 ×1 | ||
| ORKA Oruka Therapeutics, Inc. - Common Stock | $3192573 | 0.44% | 33546 | $250309 | 下跌 ×1 | ||
| XENE Xenon Pharmaceuticals Inc. - Common Shares | $3099184 | 0.43% | 51345 | $113472 | |||
| NBIX Neurocrine Biosciences, Inc. - Common Stock | $3053349 | 0.42% | 18117 | $666615 | |||
| EW Edwards Lifesciences Corporation Common Stock | $3043074 | 0.42% | 33640 | $349183 | |||
| STOK Stoke Therapeutics, Inc. - Common Stock | $2769126 | 0.38% | 84631 | $13541 | |||
| CYTK Cytokinetics, Incorporated - Common Stock | $2742692 | 0.38% | 32195 | $620720 | |||
| PYXS Pyxis Oncology, Inc. - Common Stock | $2601474 | 0.36% | 864277 | $1126129 | 下跌 ×2 | ||
| EHTH eHealth, Inc. - Common Stock | $2209368 | 0.31% | 1482797 | $296560 | |||
| CRSP CRISPR Therapeutics AG - Common Shares | $2160057 | 0.30% | 39605 | $276047 | |||
| SGMT Sagimet Biosciences Inc. - Series A Common Stock | $1932500 | 0.27% | 250000 | 上涨 ×1 | |||
| NUVB Nuvation Bio Inc. Class A Common Stock | $1855139 | 0.26% | 326609 | $-327810 | 下跌 ×3 | ||
| BNTX BioNTech SE - American Depositary Shares | $1825083 | 0.25% | 19614 | $81791 | |||
| CMPS COMPASS Pathways Plc - American Depository Shares | $1635966 | 0.23% | 115616 | $996610 | |||
| HUM Humana Inc. Common Stock | $1582922 | 0.22% | 3985 | $891963 | |||
| NAMS NewAmsterdam Pharma Company N.V. - Ordinary Shares | $1503327 | 0.21% | 44359 | 上涨 ×1 | |||
| VSTM Verastem, Inc. - Common Stock | $1182997 | 0.16% | 309685 | $-121296 | 上涨 ×1 | ||
| MDGL Madrigal Pharmaceuticals, Inc. - Common Stock | $959530 | 0.13% | 1787 | $24089 | |||
| URGN UroGen Pharma Ltd. - Ordinary Shares | $901600 | 0.12% | 24500 | $461090 | |||
| BCYC Bicycle Therapeutics plc - American Depositary Shares | $856014 | 0.12% | 201890 | $-80756 | |||
| XERS Xeris Biopharma Holdings, Inc. - Common Stock | $826927 | 0.11% | 104410 | $221349 | |||
| ABEO Abeona Therapeutics Inc. - Common Stock | $672786 | 0.09% | 108865 | $185071 | |||
| INSP Inspire Medical Systems, Inc. Common Stock | $391319 | 0.05% | 8772 | $-61141 | |||
| PRQR ProQR Therapeutics N.V. - Ordinary Shares | $351181 | 0.05% | 188807 | $45314 | |||
| ALDX Aldeyra Therapeutics, Inc. - Common Stock | $331660 | 0.05% | 155709 | $68512 | |||
| 无匹配项 | |||||||
重仓股
持仓连续增加3个季度以上。
持股数量按13F申报数据报告（未按拆股调整）
最大新仓位
本季度新开仓位，按规模从大到小排序。
季度涨幅榜
已退出持仓
包含公司事件（合并、退市）——并非所有退出都是卖出
已关闭的头寸反映了 13F 报告的变更；对于指数管理人来说，这些通常是机械性的（退市、并购、指数再平衡），而不是主动决策。
| 证券 | 季度 | 先前持股数 | 先前价值 | 退出后价格 |
|---|---|---|---|---|
| FOLD | 2026年6月30日 | 1113045 | $16094631 | 不再跟踪 |
| ALNY | 2025年12月31日 | 32320 | $14737920 | -42.2% |
| GOSS | 2026年3月31日 | 4471592 | $13861935 | -53.3% |
| SRPT | 2025年6月30日 | 210258 | $13418666 | 14.4% |
| STAA | 2025年9月30日 | 791879 | $13287730 | -13.7% |
| RNA | 2025年12月31日 | 109831 | $4785337 | -81.8% |
| DNLI | 2026年6月30日 | 234582 | $4503974 | -2.2% |
| SLRN | 2025年6月30日 | 1792895 | $4428451 | 不再跟踪 |
| NVRO | 2025年3月31日 | 750371 | $2791380 | 不再跟踪 |
| VERV | 2025年6月30日 | 575817 | $2631484 | 不再跟踪 |
| KPTIXXXX | 2025年6月30日 | 324032 | $1211880 | 不再跟踪 |
| KPTI | 2025年9月30日 | 187911 | $809896 | -71.8% |
| VYNE | 2025年9月30日 | 445434 | $734966 | 不再跟踪 |
| JSPR | 2025年3月31日 | 30651 | $655318 | -83.4% |
| ALMS | 2025年9月30日 | 143437 | $430311 | 468.1% |
| TIL | 2025年6月30日 | 11165 | $193824 | -64.0% |
| RLMD | 2025年6月30日 | 495146 | $133689 | 681.7% |
| GBIO | 2026年3月31日 | 15047 | $85467 | 不再跟踪 |
| AKTX | 2026年3月31日 | 146024 | $42201 | 54.2% |