BCYC Bicycle Therapeutics plc - American Depositary Shares
$4.13
价格 · 八月 19, 2026
截至...的财报数据 七月 30, 2026
52周区间
$4–$9
7% of range
分析师评级
BUY
16 analysts
目标价
$10
+130% upside
P/E (TTM)
-1.3
ROE
-34.2%
净利润率
-301.7%
关于 Bicycle Therapeutics plc - American Depositary Shares 公司概况（来自维基百科）
BCYC 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围
价格
$4.13
市值
$288M
P/E (TTM)
-1.3
每股收益 (TTM)
$-3.16
营收 (TTM)
$73M
股息收益率
—
ROE
-34.2%
负债/权益
—
52周区间
$4 – $9
BCYC 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图
Configure
10年表现 收入、净利润、利润率和每股收益趋势
营收与净利润
$73M
2017-12-31
→
2025-12-31
EPS
$-3.16
2019-12-31
→
2025-12-31
自由现金流
$-252M
2019-12-31
→
2025-12-31
利润率
-301.7%
估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜？
指标
5年趋势
BCYC
同行中位数
P/E (TTM)
-1.3
—
P/S (TTM) (市销率 (TTM))
4.0
5.1
P/B (市净率)
0.5
4.5
Price / FCF (股价/自由现金流)
-1.1
—
盈利能力 毛利率、营业利润率和净利率；股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)
指标
5年趋势
BCYC
同行中位数
Operating Margin (营业利润率)
-340.4%
—
Net Profit Margin (净利润率)
-301.7%
-328.5%
ROA
-26.2%
-37.9%
ROE
-34.2%
-82.2%
ROIC
-40.5%
—
财务健康 债务、流动性、偿付能力 — 资产负债表强度
指标
5年趋势
BCYC
同行中位数
Current Ratio (流动比率)
12.0
5.0
Quick Ratio (速动比率)
11.0
—
成长 营收、每股收益 (EPS) 和净利润增长：同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)
指标
5年趋势
BCYC
同行中位数
Revenue YoY (营收同比增长)
105.8%
—
Revenue CAGR 3Y (营收3年复合年增长率)
71.2%
—
Revenue CAGR 5Y (营收5年复合年增长率)
47.5%
—
资本效率 资产周转率、库存周转率、应收账款周转率
指标
5年趋势
BCYC
同行中位数
BCYC 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间
买入
16 位分析师
- 强烈买入 5 31.2%
- 买入 7 43.8%
- 持有 4 25.0%
- 卖出 0 0.0%
- 强烈卖出 0 0.0%
12个月价格目标
6 位分析师 · 2026-08-17
中位数
$9.50
← 低于所有目标
$4.13
最低
$5.00
最高
$14.00
中位数目标
$9.50
+130.0%
平均目标
$9.50
+130.0%
收益历史 每股收益实际值 vs 预估值，惊喜%，达标率，下次财报日期
平均惊喜
0.06%
| 期间 | EPS Actual | EPS 预期 | 惊喜 |
|---|---|---|---|
| 2026年6月30日 | $-0.72 | $-0.59 | -0.13% |
| 2026年3月31日 | $-0.87 | $-0.63 | -0.24% |
| 2025年12月31日 | $-0.29 | $-0.96 | 0.67% |
| 2025年9月30日 | $-0.85 | $-1.10 | 0.25% |
| 2025年6月30日 | $-1.14 | $-0.97 | -0.17% |
| 2025年3月31日 | $-0.88 | $-0.86 | -0.02% |
| 2024年12月31日 | $-0.82 | $-0.88 | 0.06% |
同行比较（GICS 子行业） 关键指标与行业同行对比
| 股票代码 | 市值 | P/E | 营收同比增长 | 净利润率 | ROE | 毛利率 |
|---|---|---|---|---|---|---|
| BCYC | $491M | -2.2 | 105.8% | -301.7% | -34.2% | — |
| AUTL | — | -1.8 | 644.9% | -381.4% | -109.6% | — |
| TLSA | — | — | — | — | — | — |
| OKYO | — | — | — | — | — | — |
| ROIV | $19.95B | -51.3 | -71.6% | -3629.2% | -6.5% | — |
完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表
损益表 15
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue | $73M | $35M | $27M | $14M | $12M | $10M | $14M | $7M | |
| R&D Expense | $240M | $173M | $156M | $82M | $45M | $33M | $26M | $21M | |
| SG&A Expense | $79M | $72M | $60M | $50M | $32M | $29M | $15M | $8M | |
| Operating Expenses | $320M | $245M | $217M | $131M | $77M | $62M | $40M | $29M | |
| Operating Income | $-247M | $-210M | $-190M | $-117M | $-66M | $-52M | $-26M | $-22M | |
| Interest Expense | · | · | $3M | $3M | $3M | $457.0K | · | · | |
| Other Non-op | $28M | $36M | $11M | $2M | $-3M | $226.0K | $-5M | $-665.0K | |
| Pretax Income | $-219M | $-174M | $-179M | $-114M | $-68M | $-52M | $-31M | $-22M | |
| Income Tax | $152.0K | $-5M | $1M | $-2M | $-2M | $-724.0K | $-254.0K | $-396.0K | |
| Net Income | $-219M | $-169M | $-181M | $-113M | $-67M | $-51M | $-31M | $-22M | |
| EPS (Basic) | $-3.16 | $-2.90 | $-5.08 | $-3.80 | $-2.67 | $-2.66 | $-2.77 | · | |
| EPS (Diluted) | $-3.16 | $-2.90 | $-5.08 | $-3.80 | $-2.67 | $-2.66 | $-2.77 | · | |
| Shares (Basic) | 69,279,838 | 58,207,593 | 35,592,362 | 29,660,659 | 25,061,734 | 19,145,938 | 11,045,370 | · | |
| Shares (Diluted) | 69,279,838 | 58,207,593 | 35,592,362 | 29,660,659 | 25,061,734 | 19,145,938 | 11,045,370 | · | |
| EBITDA | $-241M | $-203M | $-183M | $-113M | $-64M | $-51M | $-25M | · |
资产负债表 24
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $628M | $880M | $526M | $339M | $439M | $136M | $0 | $0 | |
| Receivables | $0 | $0 | $0 | $2M | $1M | $5M | $201.0K | $5M | |
| Prepaid Expense | $19M | $13M | $11M | $9M | $8M | $5M | $5M | $2M | |
| Current Assets | $683M | $929M | $562M | $369M | $459M | $156M | $104M | $77M | |
| PP&E (Net) | $6M | $10M | $15M | $19M | $3M | $2M | $2M | $2M | |
| PP&E (Gross) | · | · | $28M | $27M | $8M | $6M | $5M | $4M | |
| Accum. Depreciation | · | · | $13M | $8M | $5M | $4M | $3M | $2M | |
| Other Non-current Assets | $13M | $11M | $6M | $8M | $3M | $2M | $2M | $3M | |
| Total Assets | $718M | $957M | $595M | $411M | $480M | $161M | $110M | $82M | |
| Accounts Payable | $10M | $16M | $13M | $6M | $3M | $1M | $2M | $2M | |
| Accrued Liabilities | $44M | $41M | $32M | $26M | $14M | $12M | $6M | $7M | |
| Current Liabilities | $57M | $67M | $70M | $53M | $36M | $23M | $9M | $9M | |
| Capital Leases | $14M | $4M | $9M | $11M | $12M | $426.0K | $1M | · | |
| Other Non-current Liabilities | $1M | $1M | $5M | $4M | $3M | $3M | $2M | $897.0K | |
| Total Liabilities | $108M | $164M | $224M | $140M | $134M | $66M | $17M | $29M | |
| Long-term Debt | · | · | $31M | $30M | $30M | $15M | · | · | |
| Total Debt | · | · | $31M | $30M | $30M | $15M | · | · | |
| Common Stock | $894.0K | $890.0K | $550.0K | $387.0K | $384.0K | $266.0K | $227.0K | $10.0K | |
| Paid-in Capital | $1.51B | $1.47B | $883M | $601M | $568M | $250M | $195M | $2M | |
| Retained Earnings | $-900M | $-681M | $-512M | $-331M | $-218M | $-152M | $-101M | $-70M | |
| AOCI | $-4M | $119.0K | $-1M | $387.0K | $-3M | $-3M | $-2M | $-2M | |
| Stockholders' Equity | $610M | $793M | $371M | $271M | $346M | $95M | $93M | $-70M | |
| Liabilities + Equity | $718M | $957M | $595M | $411M | $480M | $161M | $110M | $82M | |
| Shares Outstanding | 69,367,896 | 69,061,418 | 42,431,766 | 29,873,893 | 29,579,364 | 21,094,557 | 17,993,701 | 814,728 |
现金流 16
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| D&A | $6M | $7M | $7M | $4M | $1M | $1M | $960.0K | $712.0K | |
| Stock-based Comp | $39M | $38M | $32M | $27M | $12M | $7M | $3M | $1M | |
| Deferred Tax | $-850.0K | $-5M | $3M | $-5M | $-2M | $-673.0K | $-364.0K | $-378.0K | |
| Restructuring | · | $2M | · | · | · | · | · | · | |
| Other Non-cash | $-76M | $-36M | $78M | $1M | $40M | $26M | $-2M | · | |
| Operating Cash Flow | $-250M | $-165M | $-61M | $-86M | $-15M | $-18M | $-29M | $-26M | |
| CapEx | $2M | $1M | $3M | $19M | $2M | $1M | $2M | $1M | |
| Investing Cash Flow | $-2M | $-1M | $-3M | $-19M | $-2M | $-1M | $-2M | $-1M | |
| Net Debt Issued | · | $-32M | · | · | · | · | · | · | |
| Stock Issued | · | $544M | $249M | $6M | $291M | $48M | · | · | |
| Net Stock Activity | · | $544M | $249M | $6M | $8M | · | · | · | |
| Financing Cash Flow | $-131.0K | $520M | $250M | $7M | $321M | $63M | $58M | $25M | |
| Net Change in Cash | $-251M | $353M | $188M | $-100M | $303M | $44M | $29M | $-4M | |
| Taxes Paid | $-717.0K | $792.0K | $562.0K | $2M | $73.0K | $124.0K | $117.0K | $73.0K | |
| Free Cash Flow | $-252M | $-166M | $-64M | $-105M | $-17M | $-19M | $-30M | · | |
| Levered FCF | · | · | $-67M | $-108M | $-20M | $-19M | · | · |
盈利能力 7
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -340.4% | -595.0% | -704.1% | -806.6% | -561.0% | -500.1% | -190.6% | · | |
| Net Margin | -301.7% | -479.2% | -669.7% | -779.4% | -571.2% | -490.9% | -221.8% | · | |
| Pretax Margin | -301.4% | -492.7% | -664.3% | -789.9% | -585.5% | -497.9% | -223.6% | · | |
| EBITDA Margin | -331.5% | -574.6% | -679.9% | -781.1% | -548.9% | -487.8% | -183.6% | · | |
| ROA | -26.2% | -21.8% | -35.9% | -25.3% | -20.8% | -37.6% | -31.9% | · | |
| ROE | -34.2% | -20.8% | -45.9% | -40.2% | -25.8% | -49.8% | -32.5% | · | |
| ROIC | -40.5% | -25.7% | -47.7% | -38.2% | -17.0% | -46.6% | -28.0% | · |
流动性与偿付能力 5
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 12.0 | 13.8 | 8.1 | 6.9 | 12.7 | 6.7 | 11.8 | · | |
| Quick Ratio | 11.0 | 13.1 | 7.6 | 6.4 | 12.1 | 0.2 | 0.0 | · | |
| Debt / Equity | · | · | 0.1 | 0.1 | 0.1 | 0.2 | · | · | |
| LT Debt / Equity | · | · | 0.1 | 0.1 | 0.1 | 0.2 | · | · | |
| Interest Coverage | · | · | -58.2 | -34.9 | -22.0 | -113.7 | · | · |
效率 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.1 | 0.0 | 0.1 | 0.0 | 0.0 | 0.1 | 0.1 | · | |
| Receivables Turnover | · | · | 26.4 | 9.5 | 3.6 | 3.7 | 5.3 | · |
增长率 3
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | 105.8% | 30.8% | 86.5% | 23.6% | 12.6% | · | · | · | |
| Revenue CAGR 3Y | 71.2% | 44.5% | 37.4% | · | · | · | · | · | |
| Revenue CAGR 5Y | 47.5% | · | · | · | · | · | · | · |
估值 (TTM) 14
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $73M | $35M | $27M | $14M | $12M | $10M | $14M | · | |
| Net Income TTM | $-219M | $-169M | $-181M | $-113M | $-67M | $-51M | $-31M | · | |
| Market Cap | $491M | $967M | $767M | $884M | $1.80B | $379M | $170M | · | |
| Enterprise Value | · | · | $271M | $575M | $1.39B | $393M | · | · | |
| P/E | -2.2 | -4.8 | -3.6 | -7.8 | -22.8 | -6.7 | -3.4 | · | |
| P/S | 6.8 | 27.4 | 28.4 | 61.1 | 153.9 | 36.4 | 12.3 | · | |
| P/B | 0.8 | 1.2 | 2.1 | 3.3 | 5.2 | 4.0 | 1.8 | · | |
| P / Tangible Book | 0.8 | 1.2 | 2.1 | 3.3 | 5.2 | 4.0 | · | · | |
| P / Cash Flow | -2.0 | -5.9 | -12.7 | -10.3 | -121.7 | -21.3 | -5.9 | · | |
| P / FCF | -1.9 | -5.8 | -12.1 | -8.4 | -107.0 | -19.9 | -5.6 | · | |
| EV / EBITDA | · | · | -1.5 | -5.1 | -21.7 | -7.8 | · | · | |
| EV / FCF | · | · | -4.3 | -5.5 | -82.7 | -20.7 | · | · | |
| EV / Revenue | · | · | 10.1 | 39.8 | 119.0 | 37.8 | · | · | |
| Earnings Yield | -44.6% | -20.7% | -28.1% | -12.8% | -4.4% | -14.8% | -29.4% | · |
损益表 15
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $629.0K | $887.0K | $48M | $12M | $3M | $10M | $4M | $3M | $9M | $20M | $5M | $5M | $11M | $5M | $3M | $3M | |
| R&D Expense | $41M | $49M | $52M | $58M | $71M | $59M | $50M | $48M | $40M | $35M | $45M | $40M | $40M | $32M | $25M | $23M | |
| SG&A Expense | $14M | $17M | $21M | $19M | $18M | $21M | $22M | $18M | $16M | $16M | $15M | $16M | $15M | $14M | $11M | $10M | |
| Operating Expenses | $55M | $66M | $73M | $77M | $90M | $80M | $71M | $67M | $56M | $51M | $60M | $56M | $55M | $47M | $35M | $33M | |
| Operating Income | $-55M | $-65M | $-25M | $-66M | $-87M | $-70M | $-68M | $-64M | $-47M | $-32M | $-54M | $-51M | $-43M | $-42M | $-32M | $-30M | |
| Interest Expense | · | · | · | · | · | · | · | · | · | $821.0K | · | $814.0K | $821.0K | $808.0K | · | $817.0K | |
| Other Non-op | $4M | $5M | $6M | $7M | $7M | $8M | $15M | $10M | $7M | $5M | $5M | $3M | $-9.0K | $2M | $2M | $1M | |
| Pretax Income | $-50M | $-61M | $-19M | $-59M | $-79M | $-62M | $-53M | $-54M | $-40M | $-27M | $-49M | $-48M | $-43M | $-40M | $-30M | $-29M | |
| Income Tax | $90.0K | $172.0K | $1M | $205.0K | $-231.0K | $-1M | $-1M | $-3M | $115.0K | $-350.0K | $320.0K | $2M | $-517.0K | $-618.0K | $-420.0K | $-238.0K | |
| Net Income | $-50M | $-61M | $-20M | $-59M | $-79M | $-61M | $-52M | $-51M | $-40M | $-27M | $-49M | $-50M | $-43M | $-39M | $-30M | $-28M | |
| EPS (Basic) | $-0.72 | $-0.87 | $-0.29 | $-0.85 | $-1.14 | $-0.88 | $-0.77 | $-0.74 | $-0.77 | $-0.62 | $-1.11 | $-1.26 | $-1.41 | $-1.30 | $-1.01 | $-0.96 | |
| EPS (Diluted) | $-0.72 | $-0.87 | $-0.29 | $-0.85 | $-1.14 | $-0.88 | $-0.77 | $-0.74 | $-0.77 | $-0.62 | $-1.11 | $-1.26 | $-1.41 | $-1.30 | $-1.01 | $-0.96 | |
| Shares (Basic) | 69,804,828 | 69,683,471 | -138,472,862 | 69,303,746 | 69,252,009 | 69,196,945 | -105,333,390 | 68,988,858 | 51,992,034 | 42,560,091 | -64,177,523 | 39,576,467 | 30,191,693 | 30,001,725 | -59,269,069 | 29,676,021 | |
| Shares (Diluted) | 69,804,828 | 69,683,471 | -138,472,862 | 69,303,746 | 69,252,009 | 69,196,945 | -105,333,390 | 68,988,858 | 51,992,034 | 42,560,091 | -64,177,523 | 39,576,467 | 30,191,693 | 30,001,725 | -59,269,069 | 29,676,021 | |
| EBITDA | $-55M | $-64M | · | $-66M | $-87M | $-69M | · | $-64M | $-47M | $-30M | · | $-51M | $-43M | $-40M | · | $-30M |
资产负债表 24
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $510M | $559M | $628M | $648M | $721M | $793M | $880M | $891M | $961M | $457M | $526M | $572M | $340M | $294M | $339M | $361M | |
| Receivables | · | · | $0 | · | · | $136.0K | $0 | · | $233.0K | · | · | $0 | $45M | $50M | · | $0 | |
| Prepaid Expense | $18M | $19M | $19M | $23M | $22M | $17M | $13M | $17M | $20M | $20M | · | $14M | $10M | $11M | · | $8M | |
| Current Assets | $575M | $619M | $683M | $739M | $804M | $856M | $929M | $966M | $1.03B | $516M | · | $603M | $408M | $381M | · | $381M | |
| PP&E (Net) | $5M | $6M | $6M | $7M | $8M | $9M | $10M | $12M | $12M | $13M | · | $16M | $18M | $18M | · | $16M | |
| PP&E (Gross) | · | · | · | · | · | · | · | · | $28M | $28M | · | $27M | $28M | $27M | · | $22M | |
| Accum. Depreciation | · | · | · | · | · | · | · | · | $17M | $15M | · | $11M | $10M | $9M | · | $6M | |
| Other Non-current Assets | $13M | $13M | $13M | $14M | $14M | $12M | $11M | $10M | $7M | $6M | · | $5M | $12M | $11M | · | $6M | |
| Total Assets | $607M | $652M | $718M | $764M | $832M | $884M | $957M | $997M | $1.06B | $547M | · | $639M | $454M | $429M | · | $417M | |
| Accounts Payable | $6M | $6M | $10M | $13M | $18M | $11M | $16M | $6M | $7M | $7M | · | $8M | $5M | $3M | · | $7M | |
| Accrued Liabilities | $39M | $40M | $44M | $44M | $45M | $34M | $41M | $39M | $28M | $26M | · | $34M | $37M | $25M | · | $18M | |
| Current Liabilities | $48M | $49M | $57M | $69M | $77M | $58M | $67M | $56M | $70M | $50M | · | $70M | $72M | $53M | · | $42M | |
| Capital Leases | $14M | $14M | $14M | $981.0K | $2M | $3M | $4M | $6M | $7M | $8M | · | $10M | $12M | $14M | · | $11M | |
| Other Non-current Liabilities | $931.0K | $973.0K | $1M | $1M | $1M | $1M | $1M | $6M | $5M | $5M | · | $4M | $4M | $4M | · | $3M | |
| Total Liabilities | $96M | $98M | $108M | $145M | $163M | $144M | $164M | $166M | $184M | $191M | · | $223M | $234M | $186M | · | $128M | |
| Long-term Debt | · | · | · | · | · | · | · | · | $31M | $31M | · | $31M | $31M | $30M | · | $30M | |
| Total Debt | · | · | · | · | · | · | · | · | $31M | $31M | · | $31M | $31M | $30M | · | $30M | |
| Common Stock | $900.0K | $899.0K | $894.0K | $894.0K | $893.0K | $892.0K | $890.0K | $890.0K | $889.0K | $553.0K | · | $550.0K | $396.0K | $389.0K | · | $385.0K | |
| Paid-in Capital | $1.53B | $1.52B | $1.51B | $1.50B | $1.49B | $1.48B | $1.47B | $1.46B | $1.45B | $895M | · | $875M | $633M | $613M | · | $590M | |
| Retained Earnings | $-1.01B | $-961M | $-900M | $-880M | $-820M | $-742M | $-681M | $-629M | $-578M | $-538M | · | $-463M | $-413M | $-370M | · | $-301M | |
| AOCI | $-5M | $-5M | $-4M | $-3M | $-3M | $-1M | $119.0K | $-3M | $-1M | $-778.0K | · | $3M | $-877.0K | $71.0K | · | $528.0K | |
| Stockholders' Equity | $510M | $554M | $610M | $618M | $669M | $740M | $793M | $831M | $874M | $356M | $371M | $416M | $220M | $243M | $271M | $289M | |
| Liabilities + Equity | $607M | $652M | $718M | $764M | $832M | $884M | $957M | $997M | $1.06B | $547M | · | $639M | $454M | $429M | · | $417M | |
| Shares Outstanding | 69,814,145 | 69,707,026 | 69,367,896 | 69,306,511 | 69,253,944 | 69,202,355 | 69,061,418 | 69,015,971 | 68,941,242 | 42,632,597 | 42,431,766 | 42,384,799 | 30,585,940 | 30,031,758 | 29,873,893 | 29,678,431 |
现金流 15
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $1M | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | |
| Stock-based Comp | $6M | $7M | $12M | $9M | $9M | $10M | $10M | $9M | $9M | $9M | $8M | $7M | $8M | $9M | $6M | $5M | |
| Deferred Tax | $326.0K | $-241.0K | $843.0K | $-46.0K | $-331.0K | $-1M | $-1M | $-3M | $-110.0K | $-767.0K | $-282.0K | $7M | $-2M | $-2M | $-2M | $-1M | |
| Restructuring | · | · | · | · | · | · | · | $2M | · | · | · | · | · | · | · | · | |
| Other Non-cash | · | $-13M | · | · | · | $-36M | · | · | · | $-54M | · | · | · | $-16M | · | · | |
| Operating Cash Flow | $-50M | $-66M | $-19M | $-71M | $-73M | $-86M | $-9M | $-40M | $-45M | $-71M | $-47M | $-1M | $34M | $-46M | $-30M | $-6M | |
| CapEx | $265.0K | $713.0K | $574.0K | $674.0K | $498.0K | $604.0K | $368.0K | $435.0K | $420.0K | $12.0K | $51.0K | $502.0K | $277.0K | $2M | $1M | $3M | |
| Investing Cash Flow | $-265.0K | $-713.0K | $-574.0K | $-674.0K | $-498.0K | $-604.0K | $-368.0K | $-435.0K | $-420.0K | $-12.0K | $-51.0K | $-502.0K | $-277.0K | $-2M | $-1M | $-3M | |
| Stock Issued | · | · | · | · | · | · | $0 | $-979.0K | · | · | $10.0K | $234M | $12M | $3M | · | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | · | · | · | · | $3M | · | · | |
| Financing Cash Flow | $-50.0K | $-54.0K | $-15.0K | $-30.0K | $-45.0K | $-41.0K | $203.0K | $-32M | $550M | $2M | $386.0K | $235M | $12M | $3M | $6M | $159.0K | |
| Net Change in Cash | $-50M | $-69M | $-20M | $-73M | $-72M | $-87M | $-11M | $-71M | $504M | $-69M | $-46M | $232M | $47M | $-45M | $-22M | $-11M | |
| Taxes Paid | · | · | $171.0K | $233.0K | · | · | $0 | $0 | · | · | $-102.0K | $0 | · | · | $1M | $454.0K | |
| Free Cash Flow | · | $-67M | · | · | · | $-87M | · | · | · | $-71M | · | · | · | $-49M | · | · | |
| Levered FCF | · | · | · | · | · | · | · | · | · | $-72M | · | · | · | $-49M | · | · |
盈利能力 7
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -8673.9% | -7382.4% | · | -558.6% | -2965.8% | -703.7% | · | -2385.9% | -498.3% | -162.4% | · | · | · | -853.8% | · | -978.9% | |
| Net Margin | -8002.1% | -6857.4% | · | -503.7% | -2703.8% | -608.9% | · | -1898.4% | -425.3% | -136.0% | · | · | · | -797.9% | · | -932.5% | |
| Pretax Margin | -7987.8% | -6838.0% | · | -501.9% | -2711.8% | -619.8% | · | -2027.3% | -424.1% | -137.8% | · | · | · | -810.5% | · | -940.3% | |
| EBITDA Margin | -8673.9% | -7255.1% | · | -558.6% | -2965.8% | -687.3% | · | -2385.9% | -498.3% | -153.9% | · | · | · | -822.0% | · | -978.9% | |
| ROA | -7.0% | -7.9% | · | -6.7% | -8.4% | -8.5% | · | -6.2% | -5.3% | -5.4% | · | -9.4% | -9.5% | -8.8% | · | -8.1% | |
| ROE | -8.5% | -9.4% | · | -8.2% | -10.2% | -11.1% | · | -8.2% | -7.3% | -8.9% | · | -14.1% | -16.0% | -13.6% | · | -12.3% | |
| ROIC | -10.7% | -11.8% | · | -10.6% | -12.9% | -9.3% | · | -7.2% | -5.2% | -8.1% | · | -11.9% | -17.0% | -15.0% | · | -9.2% |
流动性与偿付能力 5
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 12.1 | 12.7 | · | 10.7 | 10.4 | 14.9 | · | 17.1 | 14.8 | 10.4 | · | 8.6 | 5.7 | 7.2 | · | 9.2 | |
| Quick Ratio | 10.7 | 11.4 | · | 9.4 | 9.3 | 13.8 | · | 15.8 | 13.8 | 9.2 | · | 8.2 | 5.3 | 6.5 | · | 8.7 | |
| Debt / Equity | · | · | · | · | · | · | · | · | 0.0 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 | |
| LT Debt / Equity | · | · | · | · | · | · | · | · | 0.0 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 | |
| Interest Coverage | · | · | · | · | · | · | · | · | · | -38.6 | · | -62.4 | -52.5 | -51.7 | · | -36.4 |
效率 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | · | · | 0.0 | · | 0.0 | |
| Receivables Turnover | · | · | · | · | · | 0.4 | · | · | 0.4 | · | · | · | · | 0.2 | · | 2.1 |
估值 (TTM) 14
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $16M | $26M | · | $27M | $25M | $42M | · | $37M | $46M | $41M | · | $25M | $24M | $16M | · | $16M | |
| Net Income TTM | $-249M | $-260M | · | $-250M | $-230M | $-178M | · | $-167M | $-159M | $-158M | · | $-160M | $-137M | $-122M | · | $-97M | |
| Market Cap | $296M | $323M | · | $536M | $481M | $588M | · | $1.56B | $1.40B | $1.06B | · | $852M | $781M | $639M | · | $690M | |
| Enterprise Value | · | · | · | · | · | · | · | · | $465M | $635M | · | $310M | $471M | $375M | · | $359M | |
| P/E | -1.2 | -1.2 | · | -2.1 | -2.0 | -2.8 | · | -6.7 | -5.0 | -5.4 | · | -4.1 | -5.6 | -5.2 | · | -6.9 | |
| P/S | 18.3 | 12.7 | · | 19.6 | 19.3 | 14.1 | · | 42.3 | 30.6 | 25.8 | · | 34.5 | 32.9 | 39.5 | · | 44.2 | |
| P/B | 0.6 | 0.6 | · | 0.9 | 0.7 | 0.8 | · | 1.9 | 1.6 | 3.0 | · | 2.0 | 3.5 | 2.6 | · | 2.4 | |
| P / Tangible Book | 0.6 | 0.6 | · | 0.9 | 0.7 | 0.8 | · | 1.9 | 1.6 | 3.0 | · | 2.0 | 3.5 | 2.6 | · | 2.4 | |
| P / Cash Flow | · | -4.9 | · | · | · | -6.8 | · | · | · | -15.0 | · | · | · | -13.8 | · | · | |
| P / FCF | · | -4.9 | · | · | · | -6.8 | · | · | · | -15.0 | · | · | · | -13.2 | · | · | |
| EV / EBITDA | · | · | · | · | · | · | · | · | -10.0 | -21.1 | · | -6.1 | -10.9 | -9.3 | · | -12.1 | |
| EV / FCF | · | · | · | · | · | · | · | · | · | -9.0 | · | · | · | -7.7 | · | · | |
| EV / Revenue | · | · | · | · | · | · | · | · | 10.2 | 15.4 | · | 12.6 | 19.8 | 23.2 | · | 23.0 | |
| Earnings Yield | -84.4% | -80.6% | · | -46.6% | -50.8% | -35.4% | · | -15.0% | -20.1% | -18.4% | · | -24.5% | -17.9% | -19.2% | · | -14.5% |
财务报表 损益表、资产负债表、现金流量表 — 年度，近5年
损益表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 收入 | $73M | $35M | $27M | $14M | $12M |
| 营业利润率 % | -340.4% | -595.0% | -704.1% | -806.6% | -561.0% |
| 净收入 | $-219M | $-169M | $-181M | $-113M | $-67M |
| 稀释后每股收益 (EPS) | $-3.16 | $-2.90 | $-5.08 | $-3.80 | $-2.67 |
资产负债表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 负债/股东权益比率 | — | — | 0.1 | 0.1 | 0.1 |
| 流动比率 | 12.0 | 13.8 | 8.1 | 6.9 | 12.7 |
| 速动比率 | 11.0 | 13.1 | 7.6 | 6.4 | 12.1 |
现金流
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 自由现金流 | $-252M | $-166M | $-64M | $-105M | $-17M |
最新新闻 提及该公司的近期头条新闻
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机构持有人 (13F) 115 家申报者 · $141.9M 总计 · 截至 2026年6月30日
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
机构活动 — Q2 2026 与上一季度对比
| 新仓位 | 已退出持仓 | 增加 | 减少 | 净股数变动 |
|---|---|---|---|---|
| 23 (+7 与上一季度对比) | 12 (-13 与上一季度对比) | 36 (-8 与上一季度对比) | 19 (+2 与上一季度对比) | -669K |
与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天，外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过，优先显示最近一个已完整报告的季度对。
公司内部人士 26 位内幕人士 · 13 位高管 · 11 位董事
| 内部人士 | 角色 | 上次活动 | 持股数量 | 买入 12个月 | 卖出 12个月 | 净额 12个月 |
|---|---|---|---|---|---|---|
| Kevin Lee | CHIEF EXECUTIVE OFFICER | 2026年7月6日 S | 603671 | 0 | 2 | $-32700 |
| Travis Alvin Thompson | Chief Financial Officer | 2026年7月15日 A | 64441 | 0 | 2 | $-3945 |
| Alethia Young | Chief Financial Officer | 2024年1月2日 A | 12000 | 0 | 0 | $0 |
| Lee Kalowski | President and CFO | 2023年4月3日 S | 30309 | 0 | 0 | $0 |
| Jennifer Scott Perry | Chief Operating Officer | 2026年7月15日 A | 91052 | 0 | 3 | $-6054 |
| Alistair Milnes | Chief Operating Officer | 2024年1月2日 A | 73196 | 0 | 0 | $0 |
| Michael Charles Ferguson Hannay | CHIEF PROD & SUPPLY CHAIN OFF | 2026年7月15日 A | 94375 | 0 | 2 | $-7530 |
| Michael Skynner | CHIEF SCIENTIFIC OFFICER | 2026年7月15日 A | 157171 | 0 | 2 | $-10231 |
| Nigel Crockett | Chief Business Officer | 2024年1月2日 A | 48716 | 0 | 0 | $0 |
| Nicholas Keen | Chief Scientific Officer | 2024年1月2日 A | 63593 | 0 | 0 | $0 |
| Santiago Arroyo | Chief Development Officer | 2024年1月2日 A | 17340 | 0 | 0 | $0 |
| Dominic Smethurst | Chief Medical Officer | 2023年1月3日 A | 36699 | 0 | 0 | $0 |
| Peter Brian Leone | Chief Business Officer | 2019年5月28日 A | — | 0 | 0 | $0 |
| Janice Bourque | 董事 | 2024年1月2日 A | 16750 | 0 | 0 | $0 |
| Gregory Paul Winter | 董事 | 2024年1月2日 A | 180677 | 0 | 0 | $0 |
| Jose-Carlos Gutierrez-Ramos | 董事 | 2024年1月2日 A | 16750 | 0 | 0 | $0 |
| Pierre Legault | 董事 | 2024年1月2日 A | 33500 | 0 | 0 | $0 |
| Richard N Kender | 董事 | 2024年1月2日 A | 16750 | 0 | 0 | $0 |
| Veronica Gh Jordan | 董事 | 2024年1月2日 A | 16750 | 0 | 0 | $0 |
| Kate Bingham | 董事 | 2021年7月14日 S | 38708 | 0 | 0 | $0 |
| Carolyn Ng | 董事 | 2019年5月28日 C | 1427151 | 0 | 0 | $0 |
| Deborah Harland | 董事 | 2019年5月28日 C | 1915275 | 0 | 0 | $0 |
| Michael Anstey | 董事 | 2019年5月28日 C | 1751437 | 0 | 0 | $0 |
| Cambridge Innovation Capital (Jersey) Ltd | 10% 所有者 | 2019年5月28日 C | 1751437 | 0 | 0 | $0 |
| Vertex Global Healthcare Fund I Pte Ltd. | 10% 所有者 | 2019年5月28日 C | 1621168 | 0 | 0 | $0 |
| GSK plc | — | 2020年7月15日 S | 1910531 | 0 | 0 | $0 |
来自SEC表格3/4/5申报的内部人士；净额=仅公开市场买卖
激进投资者及 5%+ 股东 7 持仓
提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权，意图影响发行人（激进股东持股、董事会活动、并购）。每一行显示该申报人持仓的最新已知状态。
| 申报人 | 已申报 | 持股 | 状态 | 目的 | 申报 |
|---|---|---|---|---|---|
| Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC, Julian C. Baker, Felix J. Baker ×3 申报 | 2024年12月17日 | — | 初始申报 | — | SEC |
| GSK plc | 2023年7月20日 | — | 初始申报 | — | SEC |
| Tybourne Capital Management (HK) Limited, Tybourne Capital Management Limited, Tybourne Kesari Limited, Viswanathan Krishnan, Aquila Investments IV ×4 申报 | 2022年3月14日 | — | 初始申报 | — | SEC |
| GlaxoSmithKline plc ×5 申报 | 2021年9月16日 | — | 初始申报 | — | SEC |
| SVLSF V, LLC, SV Life Sciences Fund V, L.P., SV Life Sciences Fund V Strategic Partners, L.P., SV Life Sciences Fund V (GP), L.P. ×2 申报 | 2021年8月16日 | — | 初始申报 | — | SEC |
| Vertex Venture Holdings Ltd., Vertex Global HC Fund I Pte. Ltd., Vertex Venture Management Pte. Ltd. ×2 申报 | 2021年1月20日 | — | 初始申报 | 被动投资 | SEC |
| Cambridge Innovation Capital (Jersey) Limited | 2019年6月7日 | — | 初始申报 | 被动投资 | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF持仓 由 6 只交易所交易基金持有
权重仅反映直接股权持仓（N-PORT）；杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。
| 基金 | 权重 | 单位 | 截至 | 来源 |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 0.47% | 37047 NS | 2026年4月30日 | N-PORT |
| QQQS · Invesco Exchange-Traded Fund Trus... | 0.44% | 23841 SH | 2026年8月8日 | 每日 |
| SBIO · ALPS ETF Trust | 0.15% | 51450 NS | 2026年5月31日 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trus... | 0.01% | 2516 SH | 2026年8月8日 | 每日 |
| IBB · iShares Trust | 0.01% | 272825 SH | 2026年8月8日 | 每日 |
| BIB · ProShares Trust | 0.01% | 1711 NS | 2026年5月31日 | N-PORT |