| Rosalind Advisors, Inc. |
$41551898 |
3300389 |
17.08% |
股份
|
| BlackRock, Inc. |
$34078638 |
2706802 |
14.01% |
股份
|
| VANGUARD GROUP INC |
$16890806 |
1672357 |
6.94% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$15375500 |
1221247 |
6.32% |
股份
|
| Propel Bio Management, LLC |
$10971681 |
871460 |
4.51% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$9232592 |
733115 |
3.80% |
股份
|
| STATE STREET CORP |
$8552135 |
679280 |
3.52% |
股份
|
| ALGERT GLOBAL LLC |
$7311114 |
580708 |
3.01% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$7130611 |
566371 |
2.93% |
股份
|
| Divisadero Street Capital Management, LP |
$6292432 |
499796 |
2.59% |
股份
|
| MORGAN STANLEY |
$5136506 |
407983 |
2.11% |
股份
|
| ExodusPoint Capital Management, LP |
$4530940 |
359884 |
1.86% |
股份
|
| Private Wealth Advisors, LLC |
$3913765 |
310863 |
1.61% |
股份
|
| Simplify Asset Management Inc. |
$3333454 |
264770 |
1.37% |
股份
|
| NORTHERN TRUST CORP |
$3174040 |
252108 |
1.30% |
股份
|
| GOLDMAN SACHS GROUP INC |
$3151429 |
250312 |
1.30% |
股份
|
| ADAR1 Capital Management, LLC |
$2825007 |
224385 |
1.16% |
股份
|
| MARSHALL WACE, LLP |
$2756745 |
218963 |
1.13% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$2647652 |
210298 |
1.09% |
股份
|
| KENNEDY CAPITAL MANAGEMENT LLC |
$2570160 |
204143 |
1.06% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$2435510 |
193448 |
1.00% |
股份
|
| Ikarian Capital, LLC |
$2337548 |
185667 |
0.96% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$2290159 |
181903 |
0.94% |
股份
|
| Nuveen, LLC |
$2286281 |
181595 |
0.94% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$2177981 |
172993 |
0.90% |
股份
|
| CIBC WORLD MARKET INC. |
$2054789 |
163208 |
0.84% |
股份
|
| Caption Management, LLC |
$1894795 |
150500 |
0.78% |
卖出期权
|
| Lane Generational LLC |
$1884257 |
149663 |
0.77% |
股份
|
| HSBC HOLDINGS PLC |
$1705848 |
135600 |
0.70% |
股份
|
| Man Group plc |
$1617752 |
128495 |
0.67% |
股份
|
| Cubist Systematic Strategies, LLC |
$1562514 |
145350 |
0.64% |
股份
|
| Diametric Capital, LP |
$1546568 |
122841 |
0.64% |
股份
|
| Bank of New York Mellon Corp |
$1361725 |
108159 |
0.56% |
股份
|
| BARCLAYS PLC |
$1359090 |
107950 |
0.56% |
股份
|
| Caption Management, LLC |
$1259000 |
100000 |
0.52% |
买入期权
|
| Capital Advisors Wealth Management, LLC |
$1170870 |
93000 |
0.48% |
股份
|
| Jump Financial, LLC |
$1108360 |
88035 |
0.46% |
股份
|
| Jefferies Financial Group Inc. |
$1057308 |
83980 |
0.43% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$1050824 |
83465 |
0.43% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$1022308 |
81200 |
0.42% |
买入期权
|
| Stonepine Capital Management, LLC |
$1000000 |
100000 |
0.41% |
买入期权
|
| Caption Management, LLC |
$978243 |
77700 |
0.40% |
股份
|
| Russell Investments Group, Ltd. |
$851813 |
67658 |
0.35% |
股份
|
| FOX RUN MANAGEMENT, L.L.C. |
$776526 |
61678 |
0.32% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$774587 |
61524 |
0.32% |
股份
|
| Quantbot Technologies LP |
$749860 |
59560 |
0.31% |
股份
|
| D. E. Shaw & Co., Inc. |
$728885 |
57894 |
0.30% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$725864 |
57654 |
0.30% |
股份
|
| Creative Planning |
$609784 |
48434 |
0.25% |
股份
|
| UBS Group AG |
$525179 |
41714 |
0.22% |
股份
|
| Pale Fire Capital SE |
$504670 |
40085 |
0.21% |
股份
|
| WOLVERINE TRADING, LLC |
$479600 |
44000 |
0.20% |
买入期权
|
| RHUMBLINE ADVISERS |
$458822 |
36444 |
0.19% |
股份
|
| ALPS ADVISORS INC |
$441154 |
35040 |
0.18% |
股份
|
| EntryPoint Capital, LLC |
$437641 |
34761 |
0.18% |
股份
|
| SEI INVESTMENTS CO |
$394936 |
31369 |
0.16% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$378380 |
30054 |
0.16% |
股份
|
| DEUTSCHE BANK AG\ |
$368081 |
29236 |
0.15% |
股份
|
| Balyasny Asset Management L.P. |
$358412 |
28468 |
0.15% |
股份
|
| WELLS FARGO & COMPANY/MN |
$356953 |
28352 |
0.15% |
股份
|
| Leonteq Securities AG |
$348730 |
27699 |
0.14% |
股份
|
| CITADEL ADVISORS LLC |
$334894 |
26600 |
0.14% |
买入期权
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$319484 |
25376 |
0.13% |
股份
|
| Xcelsior Advisor Partners LLC |
$318527 |
25300 |
0.13% |
股份
|
| Palisades Investment Partners, LLC |
$293007 |
23273 |
0.12% |
股份
|
| WOLVERINE TRADING, LLC |
$269666 |
24740 |
0.11% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$239424 |
25800 |
0.10% |
股份
|
| MetLife Investment Management, LLC |
$235043 |
18669 |
0.10% |
股份
|
| Invesco Ltd. |
$223938 |
17787 |
0.09% |
股份
|
| WealthPlan Investment Management, LLC |
$219607 |
17443 |
0.09% |
股份
|
| NOMURA HOLDINGS INC |
$210530 |
16722 |
0.09% |
股份
|
| WOLVERINE TRADING, LLC |
$209280 |
19200 |
0.09% |
卖出期权
|
| CITADEL ADVISORS LLC |
$202699 |
16100 |
0.08% |
卖出期权
|
| CITADEL ADVISORS LLC |
$189391 |
15043 |
0.08% |
股份
|
| SkyOak Wealth, LLC |
$188850 |
15000 |
0.08% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$188850 |
15000 |
0.08% |
卖出期权
|
| ROYAL BANK OF CANADA |
$180000 |
14279 |
0.07% |
股份
|
| JPMORGAN CHASE & CO |
$167546 |
12938 |
0.07% |
股份
|
| CITIGROUP INC |
$167384 |
13295 |
0.07% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$166729 |
13243 |
0.07% |
股份
|
| TUDOR INVESTMENT CORP ET AL |
$151609 |
12042 |
0.06% |
股份
|
| LANARK FINANCIAL, INC. |
$150500 |
11954 |
0.06% |
股份
|
| MERCER GLOBAL ADVISORS INC /ADV |
$140744 |
11179 |
0.06% |
股份
|
| Vanguard Global Advisers, LLC |
$133869 |
10633 |
0.06% |
股份
|
| Schonfeld Strategic Advisors LLC |
$131136 |
10416 |
0.05% |
股份
|
| LPL Financial LLC |
$128859 |
10235 |
0.05% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$126580 |
10054 |
0.05% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$110729 |
8795 |
0.05% |
股份
|
| SHERBROOKE PARK ADVISERS LLC |
$109918 |
10883 |
0.05% |
股份
|
| Hunting Hill Global Capital, LLC |
$104716 |
11284 |
0.04% |
股份
|
| FMR LLC |
$69213 |
5497 |
0.03% |
股份
|
| Private Wealth Advisors, LLC |
$62950 |
5000 |
0.03% |
买入期权
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$60432 |
4800 |
0.02% |
股份
|
| OSAIC HOLDINGS, INC. |
$60254 |
4786 |
0.02% |
股份
|
| Point72 (DIFC) Ltd |
$53931 |
5017 |
0.02% |
股份
|
| Persistent Asset Partners Ltd |
$52954 |
4206 |
0.02% |
股份
|
| Arax Advisory Partners |
$51884 |
4121 |
0.02% |
股份
|
| IFP Advisors, Inc |
$51657 |
4103 |
0.02% |
股份
|
| Ameritas Investment Partners, Inc. |
$38714 |
3075 |
0.02% |
股份
|
| Legal & General Group Plc |
$34534 |
2743 |
0.01% |
股份
|
| CWM, LLC |
$29343 |
3162 |
0.01% |
股份
|
| Tripletail Wealth Management, LLC |
$16632 |
1260 |
0.01% |
股份
|
| AlphaQuest LLC |
$14473 |
1433 |
0.01% |
股份
|
| Federation des caisses Desjardins du Quebec |
$14176 |
1126 |
0.01% |
股份
|
| Tower Research Capital LLC (TRC) |
$13711 |
1089 |
0.01% |
股份
|
| Activest Wealth Management |
$12590 |
1000 |
0.01% |
股份
|
| Geneos Wealth Management Inc. |
$11621 |
923 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$10475 |
832 |
0.00% |
股份
|
| Allworth Financial LP |
$9506 |
755 |
0.00% |
股份
|
| Rockefeller Capital Management L.P. |
$9505 |
755 |
0.00% |
股份
|
| Quent Capital, LLC |
$7302 |
580 |
0.00% |
股份
|
| GAMMA Investing LLC |
$6446 |
512 |
0.00% |
股份
|
| TD Waterhouse Canada Inc. |
$6445 |
500 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$6421 |
510 |
0.00% |
股份
|
| Steward Partners Investment Advisory, LLC |
$6308 |
501 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$5326 |
423 |
0.00% |
股份
|
| Quaker Wealth Management, LLC |
$5036 |
400 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$4986 |
396 |
0.00% |
股份
|
| Pinnacle Wealth Planning Services, Inc. |
$3286 |
261 |
0.00% |
股份
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$3285 |
354 |
0.00% |
股份
|
| Quarry LP |
$2770 |
220 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$2217 |
176 |
0.00% |
股份
|
| PNC Financial Services Group, Inc. |
$2115 |
168 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$2042 |
162 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$1549 |
123 |
0.00% |
股份
|
| True Wealth Design, LLC |
$1335 |
106 |
0.00% |
股份
|
| US BANCORP \DE\ |
$1309 |
104 |
0.00% |
股份
|
| GSA CAPITAL PARTNERS LLP |
$1082 |
85950 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$630 |
50 |
0.00% |
股份
|
| SJS Investment Consulting Inc. |
$328 |
26 |
0.00% |
股份
|
| State of Alaska, Department of Revenue |
$327 |
26033 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$271 |
21479 |
0.00% |
股份
|
| MassMutual Private Wealth & Trust, FSB |
$252 |
20 |
0.00% |
股份
|
| Essential Partners LLC |
$239 |
19 |
0.00% |
股份
|
| Clearstead Advisors, LLC |
$126 |
10 |
0.00% |
股份
|
| Lindbrook Capital, LLC |
$76 |
6 |
0.00% |
股份
|
| Covestor Ltd |
$14 |
1099 |
0.00% |
股份
|
| Parallel Advisors, LLC |
$13 |
1 |
0.00% |
股份
|
| AllSquare Wealth Management LLC |
$11 |
1 |
0.00% |
股份
|