| RA CAPITAL MANAGEMENT, L.P. |
$36116181 |
20064545 |
33.77% |
股份
|
| VANGUARD GROUP INC |
$14405549 |
2212834 |
13.47% |
股份
|
| Commodore Capital LP |
$8055000 |
4475000 |
7.53% |
股份
|
| VIKING GLOBAL INVESTORS LP |
$6268381 |
3482434 |
5.86% |
股份
|
| Laurion Capital Management LP |
$4951539 |
2750855 |
4.63% |
股份
|
| ADAR1 Capital Management, LLC |
$4663953 |
2591085 |
4.36% |
股份
|
| Vivo Capital, LLC |
$4185000 |
2325000 |
3.91% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$3484656 |
1935920 |
3.26% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$3216177 |
1786765 |
3.01% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$2736443 |
1520246 |
2.56% |
股份
|
| BlackRock, Inc. |
$2347672 |
1304262 |
2.20% |
股份
|
| MARSHALL WACE, LLP |
$1560585 |
866992 |
1.46% |
股份
|
| CITADEL ADVISORS LLC |
$1185086 |
658381 |
1.11% |
股份
|
| AWM Investment Company, Inc. |
$1080000 |
600000 |
1.01% |
股份
|
| MONIMUS CAPITAL MANAGEMENT, LP |
$1057838 |
587688 |
0.99% |
股份
|
| Squarepoint Ops LLC |
$952349 |
529083 |
0.89% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$942806 |
523473 |
0.88% |
股份
|
| Creek Drive Management Group LLC |
$810000 |
450000 |
0.76% |
股份
|
| Ikarian Capital, LLC |
$804897 |
447165 |
0.75% |
股份
|
| DIADEMA PARTNERS LP |
$671911 |
373284 |
0.63% |
股份
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$659054 |
366141 |
0.62% |
股份
|
| Rosalind Advisors, Inc. |
$630000 |
350000 |
0.59% |
股份
|
| Driehaus Capital Management LLC |
$503836 |
279909 |
0.47% |
股份
|
| Boxer Capital Management, LLC |
$491206 |
272892 |
0.46% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$470657 |
261476 |
0.44% |
股份
|
| XTX Topco Ltd |
$441625 |
245347 |
0.41% |
股份
|
| STATE STREET CORP |
$412902 |
229390 |
0.39% |
股份
|
| Artia Global Partners LP |
$369583 |
205324 |
0.35% |
股份
|
| JANE STREET GROUP, LLC |
$310342 |
172412 |
0.29% |
股份
|
| GOLDMAN SACHS GROUP INC |
$302598 |
168110 |
0.28% |
股份
|
| Connor, Clark & Lunn Investment Management Ltd. |
$201728 |
112071 |
0.19% |
股份
|
| UBS Group AG |
$199211 |
110673 |
0.19% |
股份
|
| NORTHERN TRUST CORP |
$177728 |
98738 |
0.17% |
股份
|
| Qube Research & Technologies Ltd |
$177446 |
98581 |
0.17% |
股份
|
| RBF Capital, LLC |
$171076 |
95042 |
0.16% |
股份
|
| Persistent Asset Partners Ltd |
$171005 |
95003 |
0.16% |
股份
|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
$168660 |
93700 |
0.16% |
股份
|
| Cubist Systematic Strategies, LLC |
$141695 |
30670 |
0.13% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$135749 |
75416 |
0.13% |
股份
|
| TWO SIGMA ADVISERS, LP |
$135447 |
20806 |
0.13% |
股份
|
| Rangeley Capital, LLC |
$126000 |
70000 |
0.12% |
股份
|
| Verdad Advisers, LP |
$120384 |
66880 |
0.11% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$119282 |
66268 |
0.11% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$97319 |
54113 |
0.09% |
股份
|
| MORGAN STANLEY |
$87916 |
48842 |
0.08% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$76682 |
42601 |
0.07% |
股份
|
| Quadrature Capital Ltd |
$73685 |
40936 |
0.07% |
股份
|
| Point72 Asset Management, L.P. |
$71496 |
39720 |
0.07% |
股份
|
| Rathbones Group PLC |
$57605 |
32003 |
0.05% |
股份
|
| READYSTATE ASSET MANAGEMENT LP |
$51082 |
28379 |
0.05% |
股份
|
| Bronte Capital Management Pty Ltd. |
$31997 |
17776 |
0.03% |
股份
|
| Vanguard Global Advisers, LLC |
$31901 |
17723 |
0.03% |
股份
|
| Vanguard Personalized Indexing Management, LLC |
$31732 |
17629 |
0.03% |
股份
|
| Point72 Asia (Singapore) Pte. Ltd. |
$31240 |
6762 |
0.03% |
股份
|
| CITADEL ADVISORS LLC |
$23580 |
13100 |
0.02% |
卖出期权
|
| Aigen Investment Management, LP |
$23179 |
12877 |
0.02% |
股份
|
| China Universal Asset Management Co., Ltd. |
$19814 |
11008 |
0.02% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$19080 |
10600 |
0.02% |
卖出期权
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$18360 |
10200 |
0.02% |
买入期权
|
| GROUP ONE TRADING LLC |
$17537 |
9743 |
0.02% |
股份
|
| Tower Research Capital LLC (TRC) |
$10003 |
5557 |
0.01% |
股份
|
| JPMORGAN CHASE & CO |
$8999 |
5056 |
0.01% |
股份
|
| Zurcher Kantonalbank (Zurich Cantonalbank) |
$8071 |
4484 |
0.01% |
股份
|
| BARCLAYS PLC |
$7900 |
4389 |
0.01% |
股份
|
| Mirae Asset Global Investments Co., Ltd. |
$5569 |
3094 |
0.01% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$4855 |
2697 |
0.00% |
股份
|
| FMR LLC |
$2995 |
1664 |
0.00% |
股份
|
| CITIGROUP INC |
$2929 |
1627 |
0.00% |
股份
|
| GF FUND MANAGEMENT CO. LTD. |
$2569 |
1427 |
0.00% |
股份
|
| GSA CAPITAL PARTNERS LLP |
$1535 |
852852 |
0.00% |
股份
|
| Bare Financial Services, Inc |
$589 |
327 |
0.00% |
股份
|
| Rialto Wealth Management, LLC |
$573 |
318 |
0.00% |
股份
|
| JONES FINANCIAL COMPANIES LLLP |
$554 |
326 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$351 |
195 |
0.00% |
股份
|
| Cornerstone Financial Management LLC |
$218 |
121 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$23 |
13 |
0.00% |
股份
|
| CWM, LLC |
$9 |
5 |
0.00% |
股份
|
| ACADIAN ASSET MANAGEMENT LLC |
$1 |
869 |
0.00% |
股份
|
| ROYAL BANK OF CANADA |
$0 |
61 |
0.00% |
股份
|