TYRA Tyra Biosciences, Inc. - Common Stock
$25.34
价格 · 八月 24, 2026
截至...的财报数据 八月 4, 2026
52周区间
$12–$41
47% of range
分析师评级
BUY
22 analysts
目标价
$51
+101% upside
P/E (TTM)
-12.6
ROE
-42.7%
净利润率
—
TYRA 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围
价格
$25.34
市值
$1.36B
P/E (TTM)
-12.6
每股收益 (TTM)
$-2.01
营收 (TTM)
—
股息收益率
—
ROE
-42.7%
负债/权益
—
52周区间
$12 – $41
TYRA 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图
Configure
10年表现 收入、净利润、利润率和每股收益趋势
营收与净利润
—
EPS
$-2.01
2021-12-31
→
2025-12-31
自由现金流
$-95M
2021-12-31
→
2025-12-31
利润率
—
估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜？
指标
5年趋势
TYRA
同行中位数
P/E (TTM)
-12.6
—
P/B (市净率)
5.3
2.7
Price / FCF (股价/自由现金流)
-14.3
—
盈利能力 毛利率、营业利润率和净利率；股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)
指标
5年趋势
TYRA
同行中位数
ROA
-37.1%
-43.1%
ROE
-42.7%
-49.0%
财务健康 债务、流动性、偿付能力 — 资产负债表强度
指标
5年趋势
TYRA
同行中位数
Current Ratio (流动比率)
14.7
9.0
Quick Ratio (速动比率)
4.3
—
成长 营收、每股收益 (EPS) 和净利润增长：同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)
指标
5年趋势
TYRA
同行中位数
资本效率 资产周转率、库存周转率、应收账款周转率
指标
5年趋势
TYRA
同行中位数
TYRA 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间
买入
22 位分析师
- 强烈买入 9 40.9%
- 买入 11 50.0%
- 持有 2 9.1%
- 卖出 0 0.0%
- 强烈卖出 0 0.0%
12个月价格目标
11 位分析师 · 2026-08-23
中位数
$53.00
平均值
$50.82
← 低于所有目标
$25.34
最低
$39.00
最高
$59.00
中位数目标
$53.00
+109.2%
平均目标
$50.82
+100.5%
收益历史 每股收益实际值 vs 预估值，惊喜%，达标率，下次财报日期
平均惊喜
0.00%
| 期间 | EPS Actual | EPS 预期 | 惊喜 |
|---|---|---|---|
| 2026年6月30日 | $-0.69 | $-0.66 | -0.03% |
| 2026年3月31日 | $-0.64 | $-0.60 | -0.04% |
| 2025年12月31日 | $-0.57 | $-0.54 | -0.03% |
| 2025年9月30日 | $-0.50 | $-0.51 | 0.01% |
| 2025年6月30日 | $-0.47 | $-0.54 | 0.07% |
| 2025年3月31日 | $-0.47 | $-0.50 | 0.03% |
同行比较（GICS 子行业） 关键指标与行业同行对比
| 股票代码 | 市值 | P/E | 营收同比增长 | 净利润率 | ROE | 毛利率 |
|---|---|---|---|---|---|---|
| TYRA | $1.41B | -13.1 | — | — | -42.7% | — |
| FBRX | $353M | -5.8 | 106.6% | -2555.2% | -86.9% | — |
| ZYME | $1.97B | -24.4 | 38.9% | -76.6% | -26.9% | — |
| XNCR | $1.10B | -12.3 | 13.7% | -73.2% | -14.0% | — |
| TRAX | — | — | — | — | — | — |
| BCAX | $953M | -6.7 | — | — | -33.0% | — |
| VIR | $841M | -1.9 | -7.6% | -638.9% | -51.1% | — |
| ABSI | $529M | -4.2 | -38.2% | -4113.7% | -63.5% | — |
| INBX | $1.15B | -8.7 | 550.0% | -10773.5% | -365.9% | — |
| NVAX | $1.09B | 2.6 | 64.7% | 39.2% | -977.1% | — |
| ORIC | $806M | -5.6 | — | — | -36.5% | — |
完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表
损益表 12
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $103M | $80M | $63M | $43M | $21M | $7M | |
| SG&A Expense | $30M | $24M | $17M | $16M | $6M | $2M | |
| Operating Expenses | $133M | $104M | $80M | $59M | $26M | $9M | |
| Operating Income | $-133M | $-104M | $-80M | $-59M | $-26M | $-9M | |
| Other Non-op | $13M | $18M | $11M | $4M | $-6.0K | $-39.0K | |
| Income Tax | $0 | $0 | $0 | $2.0K | $1.0K | $1.0K | |
| Net Income | $-120M | $-86M | $-69M | $-55M | $-26M | $-9M | |
| EPS (Basic) | $-2.01 | $-1.51 | $-1.62 | $-1.32 | $-1.91 | · | |
| EPS (Diluted) | $-2.01 | $-1.51 | $-1.62 | $-1.32 | $-1.91 | · | |
| Shares (Basic) | 59,602,328 | 57,217,746 | 42,704,876 | 41,883,904 | 13,780,546 | · | |
| Shares (Diluted) | 59,602,328 | 57,217,746 | 42,704,876 | 41,883,904 | 13,780,546 | · | |
| EBITDA | $-132M | $-104M | $-80M | $-59M | $-26M | · |
资产负债表 19
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $77M | $92M | $58M | $251M | $302M | $15M | |
| Prepaid Expense | $9M | $6M | $8M | $6M | $2M | $57.0K | |
| Current Assets | $265M | $347M | $212M | $257M | $304M | $15M | |
| PP&E (Net) | $1M | $2M | $2M | $1M | $1M | $297.0K | |
| PP&E (Gross) | · | $3M | $2M | $2M | $1M | $340.0K | |
| Accum. Depreciation | · | $1M | $807.0K | $461.0K | $169.0K | $43.0K | |
| Other Non-current Assets | $9M | $7M | $5M | $4M | $312.0K | $21.0K | |
| Total Assets | $283M | $364M | $226M | $266M | $307M | $16M | |
| Accounts Payable | $1M | $590.0K | $5M | $1M | $599.0K | $664.0K | |
| Current Liabilities | $18M | $15M | $15M | $6M | $4M | $2M | |
| Capital Leases | $5M | $6M | $6M | $2M | $981.0K | $0 | |
| Other Non-current Liabilities | $0 | $3.0K | $46.0K | $169.0K | $367.0K | $140.0K | |
| Total Liabilities | $23M | $20M | $22M | $8M | $5M | $2M | |
| Common Stock | $5.0K | $5.0K | $4.0K | $4.0K | $4.0K | $0 | |
| Retained Earnings | $-371M | $-251M | $-165M | $-96M | $-40M | $-14M | |
| AOCI | $393.0K | $770.0K | $381.0K | $0 | · | · | |
| Stockholders' Equity | $259M | $343M | $204M | $258M | $302M | $-14M | |
| Liabilities + Equity | $283M | $364M | $226M | $266M | $307M | $16M | |
| Shares Outstanding | 53,706,357 | 50,749,945 | 43,024,634 | 42,353,550 | 41,441,135 | 1,829,377 |
现金流 9
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| D&A | $546.0K | $519.0K | $357.0K | $296.0K | $140.0K | $47.0K | |
| Stock-based Comp | $28M | $23M | $14M | $11M | $3M | $439.0K | |
| Other Non-cash | $-4M | $-7M | $5M | $-6M | $-478.0K | · | |
| Operating Cash Flow | $-95M | $-70M | $-50M | $-50M | $-24M | $-8M | |
| CapEx | $141.0K | $664.0K | $770.0K | $559.0K | $661.0K | $312.0K | |
| Investing Cash Flow | $72M | $-98M | $-145M | $-559.0K | $-645.0K | $-312.0K | |
| Financing Cash Flow | $8M | $202M | $2M | $632.0K | $311M | $23M | |
| Net Change in Cash | $-15M | $34M | $-193M | $-50M | $287M | $15M | |
| Free Cash Flow | $-95M | $-70M | $-51M | $-51M | $-24M | · |
盈利能力 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -37.1% | -29.3% | -28.1% | -19.3% | -16.3% | · | |
| ROE | -42.7% | -24.5% | -32.4% | -21.1% | -8.6% | · |
流动性与偿付能力 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 14.7 | 23.8 | 13.8 | 45.1 | 84.1 | · | |
| Quick Ratio | 4.3 | 6.3 | 3.8 | 44.1 | 83.6 | · |
估值 (TTM) 8
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-120M | $-86M | $-69M | $-55M | $-26M | · | |
| Market Cap | $1.41B | $705M | $596M | $322M | $583M | · | |
| P/E | -13.1 | -9.2 | -8.5 | -5.8 | -7.4 | · | |
| P/B | 5.4 | 2.1 | 2.9 | 1.2 | 1.9 | · | |
| P / Tangible Book | 5.4 | 2.1 | 2.9 | 1.2 | 1.9 | · | |
| P / Cash Flow | -14.8 | -10.1 | -11.9 | -6.4 | -24.6 | · | |
| P / FCF | -14.8 | -10.0 | -11.7 | -6.3 | -23.9 | · | |
| Earnings Yield | -7.6% | -10.9% | -11.7% | -17.4% | -13.6% | · |
损益表 11
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $39M | $33M | $28M | $25M | $24M | $25M | $22M | $23M | $18M | $17M | $21M | $19M | $12M | $10M | $10M | $11M | |
| SG&A Expense | $10M | $9M | $8M | $7M | $7M | $7M | $8M | $6M | $6M | $5M | $5M | $5M | $4M | $4M | $10M | $173.0K | |
| Operating Expenses | $49M | $42M | $37M | $33M | $31M | $32M | $30M | $29M | $24M | $22M | $26M | $24M | $16M | $14M | $15M | $14M | |
| Operating Income | $-49M | $-42M | $-37M | $-33M | $-31M | $-32M | $-30M | $-29M | $-24M | $-22M | $-26M | $-24M | $-16M | $-14M | $-15M | $-14M | |
| Other Non-op | $3M | $3M | $3M | $3M | $3M | $4M | $4M | $5M | $5M | $4M | $3M | $3M | $3M | $2M | $3M | $5.0K | |
| Net Income | $-46M | $-39M | $-34M | $-30M | $-28M | $-28M | $-26M | $-24M | $-19M | $-18M | $-23M | $-21M | $-13M | $-12M | $-13M | $-13M | |
| EPS (Basic) | $-0.69 | $-0.64 | $-0.57 | $-0.50 | $-0.47 | $-0.47 | $-0.43 | $-0.41 | $-0.32 | $-0.35 | $-0.54 | $-0.49 | $-0.31 | $-0.28 | $-0.30 | $-0.30 | |
| EPS (Diluted) | $-0.69 | $-0.64 | $-0.57 | $-0.50 | $-0.47 | $-0.47 | $-0.43 | $-0.41 | $-0.32 | $-0.35 | $-0.54 | $-0.49 | $-0.31 | $-0.28 | $-0.30 | $-0.30 | |
| Shares (Basic) | 65,991,171 | 61,746,050 | -118,955,750 | 59,670,757 | 59,550,771 | 59,336,550 | -112,554,397 | 58,874,497 | 58,668,712 | 52,228,934 | -85,147,300 | 42,868,340 | 42,589,213 | 42,394,623 | -83,442,210 | 41,997,195 | |
| Shares (Diluted) | 65,991,171 | 61,746,050 | -118,955,750 | 59,670,757 | 59,550,771 | 59,336,550 | -112,554,397 | 58,874,497 | 58,668,712 | 52,228,934 | -85,147,300 | 42,868,340 | 42,589,213 | 42,394,623 | -83,442,210 | 41,997,195 | |
| EBITDA | $-49M | $-42M | · | $-33M | $-31M | $-32M | · | $-29M | $-24M | $-22M | · | $-24M | $-16M | $-14M | · | $-14M |
资产负债表 19
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $74M | $85M | $77M | $62M | $98M | $101M | $92M | $104M | $99M | $254M | $58M | $216M | $232M | $242M | $251M | $263M | |
| Prepaid Expense | $13M | $11M | $9M | $6M | $6M | $6M | $6M | $5M | $5M | $8M | $8M | $9M | $8M | $5M | $6M | $4M | |
| Current Assets | $367M | $395M | $265M | $281M | $302M | $325M | $347M | $366M | $379M | $391M | $212M | $225M | $241M | $247M | $257M | $267M | |
| PP&E (Net) | $1M | $1M | $1M | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | $1M | $1M | $1M | |
| PP&E (Gross) | · | · | · | · | · | $3M | · | $3M | $3M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Accum. Depreciation | · | · | · | · | · | $1M | · | $1M | $1M | $926.0K | $807.0K | $706.0K | $629.0K | $544.0K | $461.0K | $379.0K | |
| Other Non-current Assets | $9M | $10M | $9M | $13M | $11M | $10M | $7M | $6M | $5M | $5M | $5M | $5M | $866.0K | $4M | $4M | $4M | |
| Total Assets | $383M | $412M | $283M | $302M | $321M | $343M | $364M | $381M | $392M | $405M | $226M | $238M | $250M | $255M | $266M | $276M | |
| Accounts Payable | $2M | $4M | $1M | $2M | $2M | $2M | $590.0K | $1M | $2M | $3M | $5M | $2M | $1M | $1M | $1M | $3M | |
| Current Liabilities | $25M | $19M | $18M | $16M | $14M | $14M | $15M | $12M | $10M | $9M | $15M | $10M | $5M | $4M | $6M | $5M | |
| Capital Leases | $5M | $5M | $5M | $5M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $2M | $2M | $3M | |
| Other Non-current Liabilities | · | · | $0 | $0 | $0 | $0 | $3.0K | $11.0K | $20.0K | $29.0K | $46.0K | $77.0K | $108.0K | $139.0K | $169.0K | $226.0K | |
| Total Liabilities | $30M | $24M | $23M | $21M | $19M | $20M | $20M | $18M | $16M | $15M | $22M | $16M | $11M | $6M | $8M | $8M | |
| Common Stock | $6.0K | $6.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | |
| Retained Earnings | $-456M | $-411M | $-371M | $-337M | $-308M | $-279M | $-251M | $-226M | $-202M | $-183M | $-165M | $-142M | $-121M | $-108M | $-96M | $-83M | |
| AOCI | $-580.0K | $107.0K | $393.0K | $442.0K | $436.0K | $688.0K | $770.0K | $2M | $-184.0K | $-6.0K | $381.0K | · | · | · | $0 | · | |
| Stockholders' Equity | $354M | $388M | $259M | $281M | $302M | $324M | $343M | $362M | $376M | $390M | $204M | $222M | $239M | $249M | $258M | $268M | |
| Liabilities + Equity | $383M | $412M | $283M | $302M | $321M | $343M | $364M | $381M | $392M | $405M | $226M | $238M | $250M | $255M | $266M | $276M | |
| Shares Outstanding | 59,662,877 | 59,469,687 | 53,706,357 | 53,318,198 | 53,233,494 | 53,089,957 | 50,749,945 | 52,871,825 | 52,736,458 | 52,474,533 | 43,024,634 | 42,928,884 | 42,817,233 | 42,535,374 | 42,353,550 | 42,136,971 |
现金流 11
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $138.0K | $138.0K | $132.0K | $131.0K | $140.0K | $143.0K | $144.0K | $127.0K | $126.0K | $122.0K | $102.0K | $86.0K | $89.0K | $83.0K | $82.0K | $82.0K | |
| Stock-based Comp | $10M | $8M | $8M | $8M | $6M | $6M | $7M | $8M | $4M | $4M | $4M | $4M | $3M | $2M | $3M | $1M | |
| Other Non-cash | · | $-1M | · | · | · | $-4M | · | · | · | $-8M | · | · | · | $-483.0K | · | · | |
| Operating Cash Flow | $-31M | $-33M | $-24M | $-22M | $-24M | $-25M | $-20M | $-18M | $-10M | $-22M | $-14M | $-17M | $-10M | $-10M | $-12M | $-12M | |
| CapEx | $66.0K | $88.0K | $57.0K | $39.0K | $31.0K | $14.0K | $6.0K | $52.0K | $470.0K | $136.0K | $603.0K | $83.0K | $43.0K | $41.0K | $21.0K | $48.0K | |
| Investing Cash Flow | $18M | $-120M | $34M | $-15M | $21M | $32M | $7M | $22M | $-145M | $18M | $-144M | $-83.0K | $-43.0K | $-41.0K | $-21.0K | $-48.0K | |
| Stock Issued | $0 | $148M | · | · | $0 | $0 | · | · | · | · | · | · | · | · | · | · | |
| Net Stock Activity | · | $148M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $2M | $160M | $5M | $647.0K | $583.0K | $2M | $706.0K | $743.0K | $373.0K | $200M | $324.0K | $467.0K | $370.0K | $376.0K | $3.0K | $364.0K | |
| Net Change in Cash | $-11M | $8M | $15M | $-37M | $-2M | $9M | $-12M | $4M | $-155M | $196M | $-158M | $-17M | $-9M | $-10M | $-12M | $-12M | |
| Free Cash Flow | · | $-33M | · | · | · | $-25M | · | · | · | $-22M | · | · | · | $-10M | · | · |
盈利能力 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -12.9% | -10.4% | · | -8.8% | -7.9% | -7.5% | · | -7.8% | -5.8% | -5.5% | · | -8.2% | -4.9% | -4.3% | · | -4.2% | |
| ROE | -13.9% | -11.1% | · | -9.3% | -8.3% | -7.9% | · | -8.2% | -6.1% | -5.7% | · | -8.6% | -5.1% | -4.4% | · | -4.3% |
流动性与偿付能力 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.9 | 20.5 | · | 17.7 | 21.9 | 22.8 | · | 29.5 | 36.5 | 44.8 | · | 22.1 | 44.5 | 67.0 | · | 48.7 | |
| Quick Ratio | 3.0 | 4.4 | · | 3.9 | 7.2 | 7.1 | · | 8.4 | 9.6 | 29.2 | · | 21.3 | 43.0 | 65.6 | · | 48.0 |
估值 (TTM) 8
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-143M | $-125M | · | $-110M | $-99M | $-89M | · | $-82M | $-71M | $-64M | · | $-59M | $-53M | $-54M | · | $-49M | |
| Market Cap | $1.91B | $2.28B | · | $746M | $509M | $494M | · | $1.24B | $843M | $861M | · | $591M | $729M | $684M | · | $370M | |
| P/E | -13.9 | -18.4 | · | -7.6 | -5.7 | -6.0 | · | -15.0 | -10.9 | -11.5 | · | -10.0 | -13.6 | -12.4 | · | -5.1 | |
| P/B | 5.4 | 5.9 | · | 2.7 | 1.7 | 1.5 | · | 3.4 | 2.2 | 2.2 | · | 2.7 | 3.1 | 2.7 | · | 1.4 | |
| P / Tangible Book | 5.4 | 5.9 | · | 2.7 | 1.7 | 1.5 | · | 3.4 | 2.2 | 2.2 | · | 2.7 | 3.1 | 2.7 | · | 1.4 | |
| P / Cash Flow | · | -69.9 | · | · | · | -19.4 | · | · | · | -39.1 | · | · | · | -69.4 | · | · | |
| P / FCF | · | -69.7 | · | · | · | -19.4 | · | · | · | -38.8 | · | · | · | -69.1 | · | · | |
| Earnings Yield | -7.2% | -5.4% | · | -13.2% | -17.4% | -16.7% | · | -6.7% | -9.2% | -8.7% | · | -10.0% | -7.3% | -8.1% | · | -19.8% |
财务报表 损益表、资产负债表、现金流量表 — 年度，近5年
损益表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 净收入 | $-120M | $-86M | $-69M | $-55M | $-26M |
| 稀释后每股收益 (EPS) | $-2.01 | $-1.51 | $-1.62 | $-1.32 | $-1.91 |
资产负债表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 流动比率 | 14.7 | 23.8 | 13.8 | 45.1 | 84.1 |
| 速动比率 | 4.3 | 6.3 | 3.8 | 44.1 | 83.6 |
现金流
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 自由现金流 | $-95M | $-70M | $-51M | $-51M | $-24M |
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机构持有人 (13F) 181 家申报者 · $1.9B 总计 · 截至 2026年6月30日
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
机构活动 — Q2 2026 与上一季度对比
| 新仓位 | 已退出持仓 | 增加 | 减少 | 净股数变动 |
|---|---|---|---|---|
| 33 (-24 与上一季度对比) | 22 (+9 与上一季度对比) | 67 (+15 与上一季度对比) | 49 (+12 与上一季度对比) | +6.1M |
与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天，外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过，优先显示最近一个已完整报告的季度对。
| 机构 | 价值 | 股份 | % 已追踪的13F | 类型 |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $389624083 | 12198625 | 20.33% | 股份 |
| FMR LLC | $259465452 | 8123527 | 13.54% | 股份 |
| Alta Partners Management Company, L.P. | $122120195 | 3823425 | 6.37% | 股份 |
| Nextech Invest Ltd. | $113501505 | 3553585 | 5.92% | 股份 |
| TCG Crossover Management, LLC | $103772421 | 3248980 | 5.42% | 股份 |
| STATE STREET CORP | $68363354 | 2140368 | 3.57% | 股份 |
| Commodore Capital LP | $59887500 | 1875000 | 3.13% | 股份 |
| Paradigm Biocapital Advisors LP | $58405708 | 1828607 | 3.05% | 股份 |
| Nextech Invest Ltd. | $56376468 | 4055861 | 2.94% | 股份 |
| VANGUARD CAPITAL MANAGEMENT LLC | $48179797 | 1508447 | 2.51% | 股份 |
| BVF INC/IL | $47149700 | 1476196 | 2.46% | 股份 |
| VANGUARD GROUP INC | $36938081 | 1405024 | 1.93% | 股份 |
| 5AM Venture Management, LLC | $32875778 | 1029298 | 1.72% | 股份 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $32482980 | 1017000 | 1.70% | 股份 |
| Hood River Capital Management LLC | $32475794 | 1016775 | 1.69% | 股份 |
| GEODE CAPITAL MANAGEMENT, LLC | $27157539 | 850108 | 1.42% | 股份 |
| Caligan Partners LP | $25775133 | 806986 | 1.35% | 股份 |
| Canaan Partners XI LLC | $23955000 | 750000 | 1.25% | 股份 |
| Siren, L.L.C. | $23156500 | 725000 | 1.21% | 股份 |
| Sio Capital Management, LLC | $22208361 | 695315 | 1.16% | 股份 |
| STEMPOINT CAPITAL LP | $20210163 | 632754 | 1.05% | 股份 |
| MARSHALL WACE, LLP | $18625268 | 583133 | 0.97% | 股份 |
| JENNISON ASSOCIATES LLC | $14403791 | 450964 | 0.75% | 股份 |
| TWO SIGMA INVESTMENTS, LP | $14366868 | 449808 | 0.75% | 股份 |
| GOLDMAN SACHS GROUP INC | $13394997 | 419380 | 0.70% | 股份 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $12872427 | 403019 | 0.67% | 股份 |
| Defilade Capital Management, L.P. | $12037228 | 376870 | 0.63% | 股份 |
| Walleye Capital LLC | $11111862 | 347898 | 0.58% | 股份 |
| Woodline Partners LP | $10222078 | 320040 | 0.53% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $9086930 | 284500 | 0.47% | 买入期权 |
| BANK OF AMERICA CORP /DE/ | $8955529 | 280386 | 0.47% | 股份 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $8550306 | 267699 | 0.45% | 股份 |
| Qube Research & Technologies Ltd | $8525872 | 266934 | 0.44% | 股份 |
| BNP PARIBAS FINANCIAL MARKETS | $7672850 | 240227 | 0.40% | 股份 |
| ALGERT GLOBAL LLC | $7637493 | 239120 | 0.40% | 股份 |
| VANGUARD FIDUCIARY TRUST CO | $7180272 | 224805 | 0.37% | 股份 |
| DIMENSIONAL FUND ADVISORS LP | $6691686 | 209508 | 0.35% | 股份 |
| Affinity Asset Advisors, LLC | $6388383 | 200012 | 0.33% | 股份 |
| FRANKLIN RESOURCES INC | $6143340 | 192340 | 0.32% | 股份 |
| HighVista Strategies LLC | $5901681 | 184774 | 0.31% | 股份 |
| MILLENNIUM MANAGEMENT LLC | $5674844 | 177672 | 0.30% | 股份 |
| CITADEL ADVISORS LLC | $5581036 | 174735 | 0.29% | 股份 |
| BOOTHBAY FUND MANAGEMENT, LLC | $5543474 | 173559 | 0.29% | 股份 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $5174280 | 162000 | 0.27% | 股份 |
| Jump Financial, LLC | $5014580 | 157000 | 0.26% | 股份 |
| VICTORY CAPITAL MANAGEMENT INC | $4873565 | 152585 | 0.25% | 股份 |
| Ensign Peak Advisors, Inc | $4680392 | 146537 | 0.24% | 股份 |
| Trexquant Investment LP | $4239716 | 132740 | 0.22% | 股份 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $3931495 | 123090 | 0.21% | 股份 |
| BARCLAYS PLC | $3631578 | 113700 | 0.19% | 买入期权 |
| ORBIMED ADVISORS LLC | $3257880 | 102000 | 0.17% | 股份 |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $2849208 | 89205 | 0.15% | 股份 |
| JANUS HENDERSON GROUP PLC | $2711816 | 70814 | 0.14% | 股份 |
| OPPENHEIMER & CO INC | $2676029 | 83783 | 0.14% | 股份 |
| XTX Topco Ltd | $2597361 | 81320 | 0.14% | 股份 |
| Kalehua Capital Management LLC | $2378412 | 74465 | 0.12% | 股份 |
| RAYMOND JAMES FINANCIAL INC | $2177094 | 68162 | 0.11% | 股份 |
| SEI INVESTMENTS CO | $2127428 | 66607 | 0.11% | 股份 |
| Squarepoint Ops LLC | $2037932 | 63805 | 0.11% | 股份 |
| Fisher Asset Management, LLC | $1923745 | 60230 | 0.10% | 股份 |
| ALPS ADVISORS INC | $1921478 | 60159 | 0.10% | 股份 |
| CITIGROUP INC | $1921383 | 60156 | 0.10% | 股份 |
| ALLIANCEBERNSTEIN L.P. | $1854486 | 48420 | 0.10% | 股份 |
| AXA Investment Managers S.A. | $1801758 | 128789 | 0.09% | 股份 |
| RHUMBLINE ADVISERS | $1662114 | 52039 | 0.09% | 股份 |
| TD Asset Management Inc | $1597000 | 50000 | 0.08% | 股份 |
| Arkadios Wealth Advisors | $1575792 | 49336 | 0.08% | 股份 |
| TWO SIGMA ADVISERS, LP | $1548481 | 58900 | 0.08% | 股份 |
| STATE OF WISCONSIN INVESTMENT BOARD | $1491502 | 46697 | 0.08% | 股份 |
| JANE STREET GROUP, LLC | $1437300 | 45000 | 0.08% | 卖出期权 |
| Susquehanna Portfolio Strategies, LLC | $1433403 | 44878 | 0.07% | 股份 |
| Swiss National Bank | $1427718 | 44700 | 0.07% | 股份 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1415804 | 44327 | 0.07% | 股份 |
| ExodusPoint Capital Management, LP | $1310370 | 41026 | 0.07% | 股份 |
| Rafferty Asset Management, LLC | $1236142 | 38702 | 0.06% | 股份 |
| Bank of New York Mellon Corp | $1224612 | 38341 | 0.06% | 股份 |
| Verdad Advisers, LP | $1149936 | 36003 | 0.06% | 股份 |
| WELLS FARGO & COMPANY/MN | $1071938 | 33561 | 0.06% | 股份 |
| Sofinnova Investments, Inc. | $1030608 | 32267 | 0.05% | 股份 |
| Engineers Gate Manager LP | $1020739 | 31958 | 0.05% | 股份 |
| BlackRock, Inc. | $841236 | 26338 | 0.04% | 股份 |
| PDT Partners, LLC | $820347 | 25684 | 0.04% | 股份 |
| MILLENNIUM MANAGEMENT LLC | $798500 | 25000 | 0.04% | 买入期权 |
| STRS OHIO | $705874 | 22100 | 0.04% | 股份 |
| MetLife Investment Management, LLC | $693833 | 21723 | 0.04% | 股份 |
| LMR Partners LLP | $675563 | 21151 | 0.04% | 股份 |
| Auour Investments LLC | $671379 | 21020 | 0.04% | 股份 |
| Vanguard Global Advisers, LLC | $643719 | 20154 | 0.03% | 股份 |
| Elmind Capital, LP | $638800 | 20000 | 0.03% | 股份 |
| PROFUND ADVISORS LLC | $625641 | 19588 | 0.03% | 股份 |
| WELLINGTON MANAGEMENT GROUP LLP | $594467 | 18612 | 0.03% | 股份 |
| Cubist Systematic Strategies, LLC | $549946 | 39310 | 0.03% | 股份 |
| AMERIPRISE FINANCIAL INC | $540425 | 16920 | 0.03% | 股份 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $538764 | 16868 | 0.03% | 股份 |
| WINTON GROUP Ltd | $536592 | 16800 | 0.03% | 股份 |
| VANGUARD ASSET MANAGEMENT, Ltd | $494399 | 15479 | 0.03% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $479100 | 15000 | 0.03% | 卖出期权 |
| Invesco Ltd. | $463897 | 14524 | 0.02% | 股份 |
| FOX RUN MANAGEMENT, L.L.C. | $461533 | 14450 | 0.02% | 股份 |
| NEW YORK STATE COMMON RETIREMENT FUND | $412761 | 12923 | 0.02% | 股份 |
公司内部人士 24 位内幕人士 · 12 位高管 · 12 位董事
| 内部人士 | 角色 | 上次活动 | 持股数量 | 买入 12个月 | 卖出 12个月 | 净额 12个月 |
|---|---|---|---|---|---|---|
| Todd Harris | President and CEO | 2026年5月5日 A | 1437631 | 0 | 0 | $0 |
| Alan Fuhrman | Chief Financial Officer | 2026年5月5日 A | 36164 | 0 | 0 | $0 |
| Esther Van Den Boom | Chief Financial Officer | 2022年9月15日 A | 121897 | 0 | 0 | $0 |
| Bhavesh Ashar | Chief Operating Officer | 2026年5月5日 A | 15013 | 0 | 0 | $0 |
| Yuliya Rueb | Vice President, Finance (PAO) | 2026年5月5日 A | 43354 | 0 | 0 | $0 |
| Douglas J Warner | Chief Medical Officer | 2026年5月5日 A | 25000 | 0 | 0 | $0 |
| Daniel Bensen | Chief Discovery Officer | 2026年2月12日 S | 146981 | 0 | 11 | $-4811405 |
| Hiroomi Tada | Chief Medical Officer | 2024年3月15日 A | 86435 | 0 | 0 | $0 |
| Patel Piyush R. | Chief Development Officer | 2023年2月21日 G | 73794 | 0 | 0 | $0 |
| Robert L. Hudkins | Chief Technology Officer | 2022年9月15日 A | 273576 | 0 | 0 | $0 |
| Ronald V. Swanson | Chief Scientific Officer | 2022年9月6日 A | 273254 | 0 | 0 | $0 |
| Ali D. Fawaz | General Counsel and Secretary | 2022年5月16日 A | — | 0 | 0 | $0 |
| Habib J Dable | 董事 | 2026年4月16日 A | — | 0 | 0 | $0 |
| Gilla Kaplan | 董事 | 2026年3月26日 M | 28231 | 0 | 1 | $-528486 |
| Robert J More | 董事 | 2025年12月19日 S | 3823425 | 0 | 2 | $-5249138 |
| Stephen Michael Rothenberg | 董事 | 2025年5月29日 A | — | 0 | 0 | $0 |
| Rehan Verjee | 董事 | 2025年5月29日 A | — | 0 | 0 | $0 |
| Susan Moran | 董事 | 2025年5月29日 A | — | 0 | 0 | $0 |
| Nina S Kjellson | 董事 | 2025年2月5日 S | 443885 | 0 | 0 | $0 |
| Adele M. Gulfo | 董事 | 2025年1月29日 A | — | 0 | 0 | $0 |
| Siddarth Subramony | 董事 | 2024年5月29日 A | — | 0 | 0 | $0 |
| Jake Simson | 董事 | 2024年5月29日 A | — | 0 | 0 | $0 |
| Isan Chen | 董事 | 2023年5月31日 A | 192783 | 0 | 0 | $0 |
| Boxer Capital Management, LLC | — | 2024年10月18日 A | 4448359 | 0 | 0 | $0 |
来自SEC表格3/4/5申报的内部人士；净额=仅公开市场买卖
激进投资者及 5%+ 股东 5 持仓
提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权，意图影响发行人（激进股东持股、董事会活动、并购）。每一行显示该申报人持仓的最新已知状态。
| 申报人 | 已申报 | 持股 | 状态 | 目的 | 申报 |
|---|---|---|---|---|---|
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×7 申报 | 2026年3月6日 | 21.20% | 修订 | — | SEC |
| MVA Investors, LLC, Aaron I. Davis, Boxer Capital Management, LLC ×3 申报 | 2024年12月6日 | — | 初始申报 | — | SEC |
| Boxer Asset Management Inc, Joe Lewis | 2024年10月15日 | — | 初始申报 | — | SEC |
| Boxer Capital, LLC, MVA Investors, LLC, Aaron I. Davis, Boxer Capital Management, LLC, Siddarth Subramony ×4 申报 | 2024年10月15日 | — | 初始申报 | — | SEC |
| Alta Partners NextGen Fund II, L.P., Alta Partners NextGen Fund II Management, LLC, Peter Hudson, Daniel Janney, Robert More | 2021年9月27日 | — | 初始申报 | 被动投资 | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF持仓 由 43 只交易所交易基金持有
权重仅反映直接股权持仓（N-PORT）；杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。
| 基金 | 权重 | 单位 | 截至 | 来源 |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 1.15% | 55509 NS | 2026年5月31日 | N-PORT |
| BBC · ETFis Series Trust I | 1.14% | 12196 NS | 2026年4月30日 | N-PORT |
| CANC · Tema ETF Trust | 0.30% | 15780 NS | 2026年5月31日 | N-PORT |
| ESSC · Strategy Shares | 0.25% | 1876 NS | 2026年4月30日 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0.25% | 37514 NS | 2026年4月30日 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0.13% | 81594 SH | 2026年8月19日 | 每日 |
| IBBQ · Invesco Exchange-Traded Fund Trus... | 0.10% | 3505 SH | 2026年8月21日 | 每日 |
| BIB · ProShares Trust | 0.09% | 1974 NS | 2026年5月31日 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0.09% | 33120 NS | 2026年4月30日 | N-PORT |
| IBB · iShares Trust | 0.08% | 330973 SH | 2026年8月21日 | 每日 |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.07% | 39429 SH | 2026年8月19日 | 每日 |
| IWO · iShares Trust | 0.06% | 339557 SH | 2026年8月21日 | 每日 |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.04% | 211804 SH | 2026年8月19日 | 每日 |
| IWM · iShares Trust | 0.03% | 937680 SH | 2026年8月21日 | 每日 |
| RSSL · Global X Funds | 0.03% | 11184 NS | 2026年4月30日 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0.02% | 7291 NS | 2026年5月31日 | N-PORT |
| RB · ProShares Trust | 0.02% | 8 NS | 2026年5月31日 | N-PORT |
| ITWO · ProShares Trust | 0.02% | 1219 NS | 2026年5月31日 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0.02% | 114471 NS | 2026年5月31日 | N-PORT |
| OMFS · Invesco Exchange-Traded Self-Inde... | 0.02% | 1805 SH | 2026年8月21日 | 每日 |
| UWM · ProShares Trust | 0.01% | 954 NS | 2026年5月31日 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.01% | 340900 SH | 2026年8月19日 | 每日 |
| VHT · VANGUARD WORLD FUND | 0.01% | 67148 SH | 2026年8月19日 | 每日 |
| URTY · ProShares Trust | 0.01% | 967 NS | 2026年5月31日 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0.01% | 6122 NS | 2026年4月30日 | N-PORT |
| ISCV · iShares Trust | 0.01% | 1827 SH | 2026年8月21日 | 每日 |
| ONEQ · Fidelity Commonwealth Trust | 0.01% | 18052 NS | 2026年5月31日 | N-PORT |
| ISCB · iShares Trust | 0.01% | 583 SH | 2026年8月21日 | 每日 |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0.00% | 1002 NS | 2026年5月31日 | N-PORT |
| ISCG · iShares Trust | 0.00% | 1509 SH | 2026年8月21日 | 每日 |
| HDG · ProShares Trust | 0.00% | 24 NS | 2026年5月31日 | N-PORT |
| WSML · iShares Trust | 0.00% | 955 SH | 2026年8月21日 | 每日 |
| DFAS · Dimensional ETF Trust | 0.00% | 12741 NS | 2026年4月30日 | N-PORT |
| ITOT · iShares Trust | 0.00% | 46934 SH | 2026年8月21日 | 每日 |
| SCHB · SCHWAB STRATEGIC TRUST | 0.00% | 13115 NS | 2026年5月31日 | N-PORT |
| IWV · iShares Trust | 0.00% | 6620 SH | 2026年8月21日 | 每日 |
| DCOR · Dimensional ETF Trust | 0.00% | 548 NS | 2026年4月30日 | N-PORT |
| DFUS · Dimensional ETF Trust | 0.00% | 1440 NS | 2026年4月30日 | N-PORT |
| DFAU · Dimensional ETF Trust | 0.00% | 682 NS | 2026年4月30日 | N-PORT |
| AVSU · AMERICAN CENTURY ETF TRUST | 0.00% | 10 NS | 2026年5月31日 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 1135472 SH | 2026年8月19日 | 每日 |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 3044 SH | 2026年8月19日 | 每日 |
| SMMV · iShares Trust | — | 4074 SH | 2026年8月19日 | 每日 |