ACAD ACADIA Pharmaceuticals Inc. - Common Stock

NASDAQ · Biotechnology · Auf SEC EDGAR ansehen ↗
$29,17
Kurs · Aug 18, 2026
Fundamentaldaten per Aug 5, 2026

Über ACADIA Pharmaceuticals Inc. - Common Stock Unternehmensübersicht von Wikipedia

Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, California.

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Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, California.

Product development

Nuplazid, a drug developed by Acadia in the late 1990s, "was designed to stimulate a subset of the brain’s serotonin receptors, or the proteins that govern memory, cognition and learning." On April 29, 2016, the FDA approved Acadia's drug, Nuplazid, for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis. Nuplazid is the trade name for Acadia's proprietary molecule, pimavanserin, a selective serotonin inverse agonist preferentially targeting 5-HT2a receptors. Acadia had partnered with Biovail in the late-stage clinical testing of the drug, which showed trial failures as of 2009.

Acadia is running multiple Phase 2 and Phase 3 trials with pimavanserin in several central nervous system conditions: dementia-related psychosis, major depressive disorder, schizophrenia inadequate response, and schizophrenia negative symptoms.

As of 1997, Acadia was among several companies that licensed compounds from Genzyme's small-molecule compound library.

In 2023, the FDA approved trofinetide (marketed as Daybue) for use in Rett syndrome.

History

Acadia started in 1993 as Receptor Technologies, based in Winooski, Vermont. In 1997, the company relocated all operations and management from Vermont to San Diego, California, as a strategic move to garner partnerships with other biotechnology companies. However, the company also had an office in Denmark, in which it received a crucial part of its early investments from BankInvest, under managing director Florian Schönharting, Kommunernes Pensionsforsikring A/S and Dansk Kapitalanlæg Aktieselskab as well as private investor Lars Christiansen. At the time, the company had fifty employees, fourteen of whom were in the Denmark office. The focus of the company in its early years was on genetic screens for receptors, aiming to accelerate early stage drug discovery.

The company planned to conduct an initial public offering (IPO) consisting of 31.6% of the company in 2001, with the intention of raising US$64 million and listing on the NASDAQ exchange under the symbol ACAD. At the time, Acadia and Allergan were collaborating on development of a treatment for glaucoma, and Allergan would retain a 6.3% ownership stake in Acadia after the IPO. However, the company's IPO, which ultimately took place in May 2004, did not fare as well as expected and netted only US$35 million. At the time, the company had five drugs in development and was running two in human trials. The company had a subsequent round of stock offering in May 2007 which raised US$102 million.

In September 2020, Acadia Pharmaceuticals acquired clinical-stage biotechnology company CerSci Therapeutics.

Corporate governance

In 2001, the company's chief executive officer at the time, Leonard R. Borrmann, left Acadia to lead Maret Pharmaceuticals. He was succeeded by Uli Hacksell, who left Acadia to lead Cerecor at the beginning of 2016.

== References ==

Quelle: Wikipedia (Englisch), CC BY-SA 4.0 · Auf Wikipedia ansehen ↗

Wikidata ↗

ACAD Aktien-Snapshot Kurs, Marktkapitalisierung, P/E, EPS, ROE, Schulden/Eigenkapital, 52-Wochen-Spanne

Kurs
$29.17
Marktkapitalisierung
$4.97B
P/E (TTM)
12.7
EPS (TTM)
$2.30
Umsatz (TTM)
$1.07B
Dividendenrendite
ROE
38.1%
Verschuldungsgrad
52W-Spanne
$20 – $30

ACAD Aktienkurs-Chart Täglich OHLCV mit technischen Indikatoren — Schwenken, Zoom und Ansicht anpassen

10-Jahres-Performance Umsatz-, Nettoergebnis-, Margen- und EPS-Trends

Umsatz & Nettoergebnis $1.07B
10-point trend, +6082.6%
2016-12-31 2025-12-31
EPS $2.30
6-point trend, +228.5%
2020-12-31 2025-12-31
Freier Cashflow $105M
10-point trend, +149.6%
2016-12-31 2025-12-31
Margen 36.5%
8-point trend, +14.6%
2016-12-31 2023-12-31

Bewertung P/E-, P/S-, P/B-, EV/EBITDA-Verhältnisse — ist die Aktie teuer oder günstig?

Kennzahl
5-Jahres-Trend
ACAD
Peer-Median
P/E (TTM)
5-point trend, +152.2%
12.7
13.2
P/S (TTM) (K/V (TTM))
5-point trend, -45.3%
4.6
55.3
P/B (K/B)
5-point trend, -46.7%
4.0
3.5
Price / FCF (Kurs / FCF)
5-point trend, +246.0%
47.2

Rentabilität Brutto-, Betriebs- und Nettomargen; ROE, ROA, ROIC

Kennzahl
5-Jahres-Trend
ACAD
Peer-Median
Operating Margin (Betriebsgewinnmarge)
5-point trend, +127.8%
9.8%
Net Profit Margin (Nettogewinnmarge)
5-point trend, +205.2%
36.5%
-151.2%
ROA
5-point trend, +225.5%
28.4%
-42.2%
ROE
5-point trend, +225.9%
38.1%
-52.8%
ROIC
5-point trend, +176.1%
24.0%

Finanzielle Gesundheit Verschuldung, Liquidität, Solvenz — Bilanzstärke

Kennzahl
5-Jahres-Trend
ACAD
Peer-Median
Current Ratio (Liquiditätsgrad)
5-point trend, -40.4%
3.8
10.3
Quick Ratio
5-point trend, -51.0%
1.1

Wachstum Umsatz-, EPS- und Nettoergebniswachstum: YoY, 3-Jahres-CAGR, 5-Jahres-CAGR

Kennzahl
5-Jahres-Trend
ACAD
Peer-Median
Revenue YoY (Umsatz YoY)
5-point trend, +121.3%
11.9%
Revenue CAGR 3Y (Umsatz CAGR 3J)
5-point trend, +121.3%
27.5%
Revenue CAGR 5Y (Umsatz CAGR 5J)
5-point trend, +121.3%
19.4%
EPS YoY (EPS VjV)
5-point trend, +319.0%
69.1%
Net Income YoY (Nettogewinn YoY)
5-point trend, +332.9%
72.7%

Kennzahlen pro Aktie EPS, Buchwert pro Aktie, Cashflow pro Aktie, Dividende pro Aktie

Kennzahl
5-Jahres-Trend
ACAD
Peer-Median
EPS (Diluted) (EPS (Verwässert))
5-point trend, +319.0%
$2.30

Kapitaleffizienz Umsatz pro Vermögenswert, Lagerumschlag, Forderungsumschlag

Kennzahl
5-Jahres-Trend
ACAD
Peer-Median

ACAD Analysten-Konsens Bullische und bärische Analystenmeinungen, 12-Monats-Kursziel, Aufwärtspotenzial

KAUF 27 Analysten
  • Starker Kauf 7 25,9%
  • Kauf 14 51,9%
  • Halten 5 18,5%
  • Verkauf 1 3,7%
  • Starker Verkauf 0 0,0%

12-Monats-Kursziel

20 Analysten · 2026-08-18
Median-Ziel $36.00 +23,4%
Mittelwert-Ziel $33.85 +16,0%

Ergebnisverlauf EPS Ist vs. Schätzung, Überraschung %, Beat-Rate, nächstes Ergebnisdatum

Durchschn. Überraschung
0.30%
Zeitraum EPS Actual EPS est. Überraschung
30. Juni 2026 $0.18 $0.06 0.12%
31. März 2026 $0.02 $0.06 -0.04%
31. Dezember 2025 $1.60 $0.14 1.5%
30. September 2025 $0.42 $0.15 0.27%
30. Juni 2025 $0.16 $0.14 0.02%
31. März 2025 $0.11 $0.11 -0.00%

Peer-Vergleich (GICS-Subbranche) Wichtige Kennzahlen im Vergleich zu Branchenkollegen

Ticker Marktkapitalisierung P/E Umsatz Vj. Nettomarge ROE Bruttogewinnmarge
ACAD $4.55B 11.6 11.9% 36.5% 38.1%
DNTH $1.78B -9.8 -67.3% -7973.3% -40.8%
CAI $7.62B -8.4 97.0% -8.4% -13.2%
PTCT $6.19B 9.8 114.5% 39.4% -331.5%
TVTX $3.47B -131.8 110.5% -5.2% -34.6%
DYN $3.23B -5.6 -57.8%
CELC $4.81B -26.3 -244.3%
RLAY $1.47B -5.3 53.4% -1800.6% -44.9%
PBLS

Vollständige Fundamentaldaten Alle Kennzahlen nach Jahr — Gewinn- und Verlustrechnung, Bilanz, Cashflow

Gewinn- und Verlustrechnung 16
Jährliche Gewinn- und Verlustrechnung-Daten für ACAD
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +892820.8% $1.07B $958M $726M $517M $484M $442M $339M $224M $125M $17M $61.0K $120.0K
Cost of Revenue 10-point trend, +2794.2% $89M $82M $42M $10M $19M $10M $11M $12M $9M $3M · ·
Gross Profit 8-point trend, +4704.9% · · $685M $507M $473M $432M $328M $211M $116M $14M · ·
R&D Expense 12-point trend, +442.6% $329M $303M $352M $362M $239M $319M $240M $187M $149M $99M $74M $61M
SG&A Expense 12-point trend, +1576.1% $549M $488M $407M $369M $396M $389M $326M $266M $255M $186M $88M $33M
Operating Expenses 12-point trend, +935.6% $967M $727M $800M $741M $655M $728M $586M $471M $417M $290M $165M $93M
Operating Income 12-point trend, +212.4% $105M $231M $-73M $-224M $-170M $-287M $-247M $-247M $-292M $-273M $-165M $-93M
Other Non-op 8-point trend, +228.9% $2M $2M $5M $4M $2M $-997.0K $997.0K $-2M · · · ·
Pretax Income 12-point trend, +250.2% $139M $258M $-51M $-213M $-168M $-281M $-234M $-244M $-288M $-270M $-164M $-92M
Income Tax 12-point trend, -252096000.00 $-252M $32M $10M $3M $351.0K $611.0K $876.0K $1M $1M $1M $330.0K $0
Net Income 12-point trend, +522.8% $391M $226M $-61M $-216M $-168M $-282M $-235M $-245M $-289M $-271M $-164M $-92M
EPS (Basic) 6-point trend, +229.6% $2.32 $1.37 $-0.37 $-1.34 $-1.05 $-1.79 · · · · · ·
EPS (Diluted) 6-point trend, +228.5% $2.30 $1.36 $-0.37 $-1.34 $-1.05 $-1.79 · · · · · ·
Shares (Basic) 6-point trend, +106907.5% 168,356,000 165,717,000 163,819,000 161,683,000 160,493 157,331 · · · · · ·
Shares (Diluted) 6-point trend, +107901.0% 169,919,000 166,362,000 163,819,000 161,683,000 160,493 157,331 · · · · · ·
EBITDA 12-point trend, +212.4% $105M $231M $-73M $-224M $-170M $-287M $-247M $-247M $-292M $-273M $-165M $-93M
Bilanz 25
Jährliche Bilanz-Daten für ACAD
Kennzahl Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +187.3% $178M $320M $189M $115M $147M $326M $190M $135M $69M $164M $102M $62M
Receivables 10-point trend, +1957.5% $121M $99M $98M $62M $64M $48M $36M $26M $17M $6M · ·
Inventory 10-point trend, +2567.6% $111M $92M $40M $12M $14M $10M $6M $4M $5M $4M · ·
Prepaid Expense 12-point trend, +4996.4% $60M $56M $39M $21M $24M $26M $19M $21M $8M $8M $2M $1M
Current Assets 12-point trend, +227.2% $1.06B $938M $616M $508M $618M $718M $760M $526M $373M $548M $219M $325M
PP&E (Net) 12-point trend, +1258.2% $8M $4M $5M $6M $8M $9M $3M $3M $3M $3M $2M $553.0K
PP&E (Gross) 12-point trend, +531.1% $17M $14M $14M $14M $14M $13M $9M $8M $7M $6M $5M $3M
Accum. Depreciation 12-point trend, +343.2% $9M $10M $10M $8M $6M $4M $5M $4M $4M $3M $3M $2M
Intangibles 10-point trend, +1452.3% $109M $120M $65M $0 $0 $1M $3M $4M $6M $7M · ·
Other Non-current Assets 12-point trend, +1257.5% $4M $359.0K $476.0K $8M $4M $2M $3M $2M $354.0K $785.0K $329.0K $287.0K
Total Assets 12-point trend, +380.6% $1.56B $1.19B $749M $588M $700M $783M $783M $540M $385M $561M $222M $325M
Accounts Payable 12-point trend, +440.8% $11M $16M $18M $13M $7M $8M $7M $3M $9M $4M $2M $2M
Accrued Liabilities 12-point trend, +1826.6% $266M $379M $237M $113M $89M $97M $68M $56M $40M $36M $20M $14M
Current Liabilities 12-point trend, +1650.1% $277M $395M $254M $126M $96M $106M $75M $60M $49M $43M $22M $16M
Capital Leases 7-point trend, +537.5% $41M $42M $48M $53M $56M $44M $6M · · · · ·
Deferred Tax 7-point trend, +345.4% $11M $11M $12M $13M $14M $13M $3M · · · · ·
Other Non-current Liabilities 8-point trend, +1128.3% $19M $18M $15M $9M $7M $5M $3M $2M · · · ·
Total Liabilities 12-point trend, +2009.1% $337M $455M $317M $187M $159M $156M $84M $61M $49M $43M $22M $16M
Common Stock 12-point trend, +60.0% $16.0K $16.0K $16.0K $16.0K $16.0K $16.0K $15.0K $14.0K $12.0K $12.0K $10.0K $10.0K
Paid-in Capital 3-point trend, +79.8% · · · · · · · · · $1.45B $862M $808M
Retained Earnings 12-point trend, -264.0% $-1.81B $-2.20B $-2.43B $-2.37B $-2.15B $-1.99B $-1.70B $-1.47B $-1.22B $-934M $-663M $-498M
AOCI 12-point trend, +16155.6% $1M $292.0K $24.0K $-975.0K $-192.0K $36.0K $297.0K $-372.0K $-399.0K $106.0K $11.0K $-9.0K
Stockholders' Equity 12-point trend, +296.6% $1.23B $733M $432M $400M $541M $627M $699M $479M $335M $518M $200M $309M
Liabilities + Equity 12-point trend, +380.6% $1.56B $1.19B $749M $588M $700M $783M $783M $540M $385M $561M $222M $325M
Shares Outstanding 12-point trend, +70.2% 170,309,376 166,708,856 164,650,219 162,064,872 161,012,695 159,637,771 155,275,300 143,853,597 124,410,552 121,367,169 101,938,702 100,047,331
Cashflow 13
Jährliche Cashflow-Daten für ACAD
Kennzahl Trend 202520242023202220212020201920182017201620152014
D&A · · · · · · · · · · · $206.0K
Stock-based Comp 12-point trend, +225.1% $52M $67M $66M $68M $64M $84M $82M $82M $76M $55M $40M $16M
Deferred Tax 5-point trend, -71417.4% $-250M $0 $0 $3M $351.0K · · · · · · ·
Amort. of Intangibles 12-point trend, +10889000.00 $11M $15M $4M $0 $1M $1M $1M $1M $1M $985.0K $0 $0
Operating Cash Flow 12-point trend, +265.3% $110M $158M $17M $-114M $-126M $-136M $-151M $-167M $-218M $-208M $-122M $-66M
CapEx 12-point trend, +2505.6% $5M $523.0K $50.0K $0 $1M $8M $1M $2M $812.0K $2M $2M $180.0K
Investing Cash Flow 10-point trend, -15.5% $-303M $-31M $32M $73M $-71M $193M $-166M $-71M $92M $-262M · ·
Stock Issued 12-point trend, -75.5% $50M $7M $25M $8M $18M $81M $372M $307M $31M $519M $15M $204M
Net Stock Activity 12-point trend, -75.5% $50M $7M $25M $8M $18M $81M $372M $307M $31M $519M $15M $204M
Financing Cash Flow 10-point trend, -90.7% $50M $7M $25M $8M $18M $81M $372M $307M $31M $534M · ·
Net Change in Cash 12-point trend, -384.8% $-143M $134M $74M $-33M $-179M $137M $55M $68M $-94M $63M $40M $50M
Taxes Paid 11-point trend, +5965.1% $25M $20M $6M $2M $1M $1M $2M $1M $1M $-365.0K $415.0K ·
Free Cash Flow 12-point trend, +257.8% $105M $157M $17M $-114M $-127M $-144M $-152M $-170M $-219M $-212M $-124M $-67M
Rentabilität 8
Jährliche Rentabilität-Daten für ACAD
Kennzahl Trend 202520242023202220212020201920182017201620152014
Gross Margin 8-point trend, +14.6% · · 94.3% 98.0% 97.8% 97.7% 96.7% 94.5% 92.7% 82.2% · ·
Operating Margin 12-point trend, +100.0% 9.8% 24.1% -10.1% -43.2% -35.2% -64.9% -72.7% -110.6% -234.1% -1574.1% -269855.7% -77691.7%
Net Margin 12-point trend, +100.0% 36.5% 23.6% -8.4% -41.8% -34.7% -63.7% -69.4% -109.6% -231.7% -1565.9% -269578.7% -77062.5%
Pretax Margin 11-point trend, +100.0% 13.0% 26.9% -7.0% -41.3% -34.6% -63.6% -69.1% -109.0% -230.8% -1558.2% -269037.7% ·
EBITDA Margin 12-point trend, +100.0% 9.8% 24.1% -10.1% -43.2% -35.2% -64.9% -72.7% -110.6% -234.1% -1574.1% -269855.7% -77691.7%
ROA 12-point trend, +179.1% 28.4% 23.4% -9.2% -33.5% -22.6% -36.0% -35.5% -53.0% -61.2% -69.3% -60.1% -35.9%
ROE 12-point trend, +201.4% 38.1% 34.6% -15.4% -52.3% -30.3% -43.9% -33.9% -69.8% -67.8% -75.6% -64.6% -37.6%
ROIC 11-point trend, +129.1% 24.0% 27.6% -20.4% -56.5% -31.6% -45.8% -35.4% -51.9% -87.5% -52.9% -82.6% ·
Liquidität & Solvenz 2
Jährliche Liquidität & Solvenz-Daten für ACAD
Kennzahl Trend 202520242023202220212020201920182017201620152014
Current Ratio 12-point trend, -81.3% 3.8 2.4 2.4 4.0 6.4 6.8 10.2 8.8 7.6 12.9 10.0 20.5
Quick Ratio 12-point trend, -72.4% 1.1 1.1 1.1 1.4 2.2 3.5 3.0 2.7 1.8 4.0 4.7 3.9
Effizienz 3
Jährliche Effizienz-Daten für ACAD
Kennzahl Trend 202520242023202220212020201920182017201620152014
Asset Turnover 12-point trend, +155640.0% 0.8 1.0 1.1 0.8 0.7 0.6 0.5 0.5 0.3 0.0 0.0 0.0
Inventory Turnover 9-point trend, -40.5% 0.9 1.2 1.6 0.8 0.9 1.3 2.2 · 1.9 1.5 · ·
Receivables Turnover 10-point trend, +65.7% 9.7 9.7 9.1 8.2 8.6 10.5 11.0 10.3 10.7 5.9 · ·
Pro Aktie 5
Jährliche Pro Aktie-Daten für ACAD
Kennzahl Trend 202520242023202220212020201920182017201620152014
Book Value / Share 12-point trend, +133.0% $7.21 $4.40 $2.62 $2.47 $3.36 $3.93 $4.50 $3.33 $2.69 $4.27 $1.96 $3.09
Revenue / Share 4-point trend, -99.8% $6.31 $5.76 $4434.39 $3199.07 · · · · · · · ·
Cash Flow / Share 4-point trend, +100.1% $0.65 $0.95 $101.95 $-705.30 · · · · · · · ·
Cash / Share 12-point trend, +68.8% $1.04 $1.92 $1.15 $0.71 $0.92 $2.04 $1.22 $0.94 $0.56 $1.35 $1.00 $0.62
EPS (TTM) 6-point trend, +228.5% $2.30 $1.36 $-0.37 $-1.34 $-1.05 $-1.79 · · · · · ·
Wachstumsraten 5
Jährliche Wachstumsraten-Daten für ACAD
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +23.6% 11.9% 31.9% 40.5% 6.8% 9.6% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +52.4% 27.5% 25.5% 18.0% · · · · · · · · ·
Revenue CAGR 5Y 19.4% · · · · · · · · · · ·
EPS YoY 69.1% · · · · · · · · · · ·
Net Income YoY 72.7% · · · · · · · · · · ·
Bewertung (TTM) 10
Jährliche Bewertung (TTM)-Daten für ACAD
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +892820.8% $1.07B $958M $726M $517M $484M $442M $339M $224M $125M $17M $61.0K $120.0K
Net Income TTM 12-point trend, +522.8% $391M $226M $-61M $-216M $-168M $-282M $-235M $-245M $-289M $-271M $-164M $-92M
Market Cap 12-point trend, +43.2% $4.55B $3.06B $5.16B $2.58B $3.76B $8.53B $6.64B $2.33B $3.75B $3.50B $3.63B $3.18B
P/E 6-point trend, +138.9% 11.6 13.5 -84.6 -11.9 -22.2 -29.9 · · · · · ·
P/S 12-point trend, -100.0% 4.2 3.2 7.1 5.0 7.8 19.3 19.6 10.4 30.0 202.0 59575.7 26470.9
P/B 12-point trend, -63.9% 3.7 4.2 11.9 6.4 6.9 13.6 9.5 4.9 11.2 6.8 18.2 10.3
P / Tangible Book 6-point trend, -70.2% 4.1 5.0 14.1 6.4 6.9 13.6 · · · · · ·
P / Cash Flow 12-point trend, +186.6% 41.4 19.4 308.7 -22.6 -29.9 -62.7 -44.0 -13.9 -17.2 -16.6 -29.8 -47.8
P / FCF 12-point trend, +190.7% 43.3 19.5 309.6 -22.6 -29.6 -59.4 -43.6 -13.7 -17.1 -16.5 -29.3 -47.7
Earnings Yield 6-point trend, +357.0% 8.6% 7.4% -1.2% -8.4% -4.5% -3.4% · · · · · ·

Finanzberichte Gewinn- und Verlustrechnung, Bilanz, Cashflow — jährlich, letzte 5 Jahre

Gewinn- und Verlustrechnung
2025-12-312024-12-312023-12-312022-12-312021-12-31
Umsatz $1.07B$958M$726M$517M$484M
Bruttogewinnmarge % 94.3%98.0%97.8%
Betriebsgewinnmarge % 9.8%24.1%-10.1%-43.2%-35.2%
Nettoergebnis $391M$226M$-61M$-216M$-168M
Verwässerte EPS $2.30$1.36$-0.37$-1.34$-1.05
Bilanz
2025-12-312024-12-312023-12-312022-12-312021-12-31
Liquiditätsgrad 3.82.42.44.06.4
Quick Ratio 1.11.11.11.42.2
Cashflow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Freier Cashflow $105M$157M$17M$-114M$-127M

Neueste Nachrichten Aktuelle Schlagzeilen über dieses Unternehmen

Handelssignale Aktuelle Kauf-/Verkaufssignale mit Einstiegspreis und Risiko-Ertrags-Verhältnis

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Institutionelle Eigentümer (13F) 387 Einreicher · $3.2B gesamt · Stand 30. Juni 2026

Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.

Institutionelle Aktivität — Q2 2026 vs. Vorquartal
Neue Positionen Geschlossene Positionen Erhöht Abgenommen Nettoveränderung der Aktien
56 (+10 vs. Vorquartal) 37 (+10 vs. Vorquartal) 136 (+11 vs. Vorquartal) 100 (-13 vs. Vorquartal) +17.3M

Verglichen mit Q1 2026. SEC-Formular 13F-Einreichungen sind innerhalb von 45 Tagen nach Quartalsende fällig, zuzüglich einer kurzen Pufferzeit für verspätete Einreicher — Quartale, die noch in diesem Fenster liegen, werden zugunsten des letzten vollständig berichteten Paares übersprungen.

Institution Wert Aktien % der verfolgten 13F Typ
BAKER BROS. ADVISORS LP $1.085.696.471 42.912.904 33,44% Aktien
STATE STREET CORP $229.628.164 9.076.212 7,07% Aktien
VANGUARD PORTFOLIO MANAGEMENT LLC $223.612.785 8.838.450 6,89% Aktien
RTW INVESTMENTS, LP $180.756.457 7.144.524 5,57% Aktien
VANGUARD CAPITAL MANAGEMENT LLC $145.822.875 5.763.750 4,49% Aktien
DIMENSIONAL FUND ADVISORS LP $88.971.384 3.516.656 2,74% Aktien
GEODE CAPITAL MANAGEMENT, LLC $73.088.127 2.888.204 2,25% Aktien
Qube Research & Technologies Ltd $61.899.233 2.446.610 1,91% Aktien
Point72 Asset Management, L.P. $61.559.150 2.433.168 1,90% Aktien
CITADEL ADVISORS LLC $53.414.195 2.111.233 1,65% Aktien
Pictet Asset Management Holding SA $50.146.450 1.983.198 1,54% Aktien
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $49.826.959 1.969.445 1,53% Aktien
MARSHALL WACE, LLP $44.649.289 1.764.794 1,38% Aktien
BRAIDWELL LP $41.653.895 1.646.399 1,28% Aktien
NORGES BANK $41.069.692 1.623.308 1,26% Aktien
Frazier Life Sciences Management, L.P. $36.386.409 1.438.198 1,12% Aktien
Artisan Partners Limited Partnership $33.525.890 1.325.134 1,03% Aktien
RENAISSANCE TECHNOLOGIES LLC $32.449.679 1.282.596 1,00% Aktien
GOLDMAN SACHS GROUP INC $32.070.584 1.267.612 0,99% Aktien
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $30.520.301 1.206.336 0,94% Aktien
D. E. Shaw & Co., Inc. $28.330.257 1.119.773 0,87% Aktien
Allspring Global Investments Holdings, LLC $26.143.513 1.037.441 0,81% Aktien
TWO SIGMA INVESTMENTS, LP $23.452.898 926.992 0,72% Aktien
VANGUARD FIDUCIARY TRUST CO $23.082.961 912.370 0,71% Aktien
BANK OF AMERICA CORP /DE/ $21.702.062 857.789 0,67% Aktien
PANAGORA ASSET MANAGEMENT INC $17.985.922 710.906 0,55% Aktien
Fisher Asset Management, LLC $17.690.535 699.230 0,54% Aktien
Allianz Asset Management GmbH $15.730.341 706.664 0,48% Aktien
RICE HALL JAMES & ASSOCIATES, LLC $15.657.841 618.887 0,48% Aktien
MILLENNIUM MANAGEMENT LLC $14.925.077 589.924 0,46% Aktien
MANUFACTURERS LIFE INSURANCE COMPANY, THE $14.771.456 583.852 0,45% Aktien
ADAGE CAPITAL PARTNERS GP, L.L.C. $12.903.000 510.000 0,40% Aktien
Hudson Bay Capital Management LP $11.764.500 465.000 0,36% Aktien
GLENMEDE TRUST CO NA $11.656.544 460.733 0,36% Aktien
JUPITER ASSET MANAGEMENT LTD $11.599.190 458.466 0,36% Aktien
Public Sector Pension Investment Board $11.014.988 435.375 0,34% Aktien
MACKENZIE FINANCIAL CORP $10.646.872 420.825 0,33% Aktien
Ishara Investments LP $10.373.000 410.000 0,32% Aktien
TWO SIGMA ADVISERS, LP $9.888.042 370.200 0,30% Aktien
Balyasny Asset Management L.P. $9.817.007 388.024 0,30% Aktien
BlackRock, Inc. $9.281.482 366.857 0,29% Aktien
SPHERA FUNDS MANAGEMENT LTD. $9.020.310 356.534 0,28% Aktien
AMERIPRISE FINANCIAL INC $8.039.177 317.754 0,25% Aktien
PRUDENTIAL FINANCIAL INC $7.985.313 315.625 0,25% Aktien
Alyeska Investment Group, L.P. $7.850.261 310.287 0,24% Aktien
RHUMBLINE ADVISERS $7.663.389 302.902 0,24% Aktien
Schonfeld Strategic Advisors LLC $7.189.171 284.157 0,22% Aktien
Edgestream Partners, L.P. $7.167.515 283.301 0,22% Aktien
Logos Global Management LP $6.325.000 250.000 0,19% Aktien
LAZARD ASSET MANAGEMENT LLC $6.263.496 247.569 0,19% Aktien
FMR LLC $6.052.317 239.222 0,19% Aktien
Swiss National Bank $5.841.871 230.904 0,18% Aktien
VICTORY CAPITAL MANAGEMENT INC $5.432.213 214.712 0,17% Aktien
ALPS ADVISORS INC $4.985.340 197.049 0,15% Aktien
ENVESTNET ASSET MANAGEMENT INC $4.926.239 194.713 0,15% Aktien
Legal & General Group Plc $4.918.245 194.397 0,15% Aktien
FIRST TRUST ADVISORS LP $4.664.965 184.386 0,14% Aktien
NEW YORK STATE COMMON RETIREMENT FUND $4.364.807 172.522 0,13% Aktien
Birchview Capital, LP $4.326.300 171.000 0,13% Aktien
MARTINGALE ASSET MANAGEMENT L P $4.247.693 167.893 0,13% Aktien
Tetragon Partners GP Ltd $4.247.238 167.875 0,13% Aktien
GREAT LAKES ADVISORS, LLC $3.822.526 151.088 0,12% Aktien
AMERICAN CENTURY COMPANIES INC $3.635.306 143.688 0,11% Aktien
STEMPOINT CAPITAL LP $3.622.125 143.167 0,11% Aktien
ALLIANCEBERNSTEIN L.P. $3.585.329 161.066 0,11% Aktien
Squarepoint Ops LLC $3.542.329 140.013 0,11% Aktien
ORBIMED ADVISORS LLC $3.466.100 137.000 0,11% Aktien
Erste Asset Management GmbH $3.369.240 133.700 0,10% Aktien
Emerald Investment Advisers, LLC $3.333.326 131.752 0,10% Aktien
Caption Management, LLC $3.289.000 130.000 0,10% Verkaufsoption
VANGUARD ASSET MANAGEMENT, Ltd $3.130.217 123.724 0,10% Aktien
WELLS FARGO & COMPANY/MN $3.084.475 121.916 0,09% Aktien
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $3.077.311 138.244 0,09% Aktien
Longaeva Partners L.P. $2.968.145 117.318 0,09% Aktien
JACOBS LEVY EQUITY MANAGEMENT, INC $2.948.791 116.553 0,09% Aktien
Trexquant Investment LP $2.935.357 116.022 0,09% Aktien
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $2.909.778 115.011 0,09% Aktien
JONES FINANCIAL COMPANIES LLLP $2.868.477 113.289 0,09% Aktien
Rafferty Asset Management, LLC $2.789.426 110.254 0,09% Aktien
Nan Fung Group Holdings Ltd $2.605.495 102.984 0,08% Aktien
RAYMOND JAMES FINANCIAL INC $2.406.232 95.108 0,07% Aktien
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $2.344.000 92.648 0,07% Aktien
ROYCE & ASSOCIATES LP $2.324.691 91.885 0,07% Aktien
HOHIMER WEALTH MANAGEMENT, LLC $2.322.540 91.800 0,07% Aktien
Point72 Europe (London) LLP $2.305.047 108.015 0,07% Aktien
VIRGINIA RETIREMENT SYSTEMS ET Al $2.134.076 79.898 0,07% Aktien
Campbell & CO Investment Adviser LLC $2.108.527 83.341 0,06% Aktien
Verdad Advisers, LP $2.090.514 82.629 0,06% Aktien
VOYA INVESTMENT MANAGEMENT LLC $2.072.576 81.920 0,06% Aktien
CITADEL ADVISORS LLC $2.049.300 81.000 0,06% Kaufoption
GUGGENHEIM CAPITAL LLC $1.979.776 78.252 0,06% Aktien
WESBANCO BANK INC $1.978.460 78.200 0,06% Aktien
Phocas Financial Corp. $1.954.299 77.245 0,06% Aktien
MetLife Investment Management, LLC $1.899.043 75.061 0,06% Aktien
STATE OF WISCONSIN INVESTMENT BOARD $1.850.493 73.142 0,06% Aktien
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $1.788.331 70.685 0,06% Aktien
Freestone Grove Partners LP $1.755.643 69.393 0,05% Aktien
CenterBook Partners LP $1.743.878 68.928 0,05% Aktien
CANADA PENSION PLAN INVESTMENT BOARD $1.722.930 68.100 0,05% Aktien
Illinois Municipal Retirement Fund $1.693.380 66.932 0,05% Aktien

Unternehmensinsider 37 Insider · 19 Führungskräfte · 19 Direktoren

Insider Rolle Letzte Aktivität Gehaltene Aktien Käufe 12m Verkäufe 12m Netto 12m
Stephen Davis CEO 6. Januar 2024 M 96.521 0 0 $0
Uli Hacksell CEO 25. März 2011 A 69.916 0 0 $0
Elena Ridloff EVP and CFO 29. April 2021 M 10.553 0 0 $0
Todd S. Young EVP AND CFO 15. Oktober 2018 A 0 0 $0
Thomas H Aasen Exec. VP, CFO & CBO 25. März 2011 A 13.899 0 0 $0
Srdjan R. Stankovic President 21. November 2022 M 61.234 0 0 $0
Mark R Brann President & CSO 16. Juni 2006 S 317.756 0 0 $0
Brendan Teehan EVP, COO, Head of Commercial 6. Januar 2024 M 30.949 0 0 $0
Elizabeth H.Z. Thompson EVP, Head of Research & Dev 29. Juli 2026 M 18.994 0 2 $-432.662
James Kihara PRINCIPAL ACCOUNTING OFFICER 26. Juni 2026 S 13.088 0 2 $-412.253
Austin D. Kim EVP,General Counsel, Secretary 6. Januar 2024 M 46.901 0 0 $0
Douglas J Williamson Executive VP, Research & Dev 10. Februar 2023 A 0 0 $0
Michael J. Yang EVP and CCO 6. Januar 2021 M 8.059 0 0 $0
Eric Alejandro Miller Controller & PAO 15. Oktober 2019 M 270 0 0 $0
Glenn Baity VP, GC & Sec. 25. März 2011 A 0 0 $0
Roger Mills Executive VP, Development 25. März 2011 A 0 0 $0
Bo-Ragnar Tolf VP/Mg. Dir. ACADIA Pharma AB 8. Juli 2009 M 20.000 0 0 $0
Brian Lundstrom Sr. VP, Bus. Development 7. März 2008 A 0 0 0 $0
Robert E Davis Exec. VP, Drug Discovery 11. März 2005 A 0 0 $0
Adora Ndu Direktor 29. Mai 2026 A 32.908 0 0 $0
Elizabeth A. Garofalo Direktor 29. Mai 2026 A 33.489 0 0 $0
Jonathan Poole Direktor 29. Mai 2026 A 2.010 0 0 $0
James M Daly Direktor 29. Mai 2026 A 12.148 0 0 $0
Laura Brege Direktor 29. Mai 2026 A 23.202 0 0 $0
Edmund Harrigan Direktor 29. Mai 2026 A 43.148 0 0 $0
Daniel B Soland Direktor 1. Juni 2023 A 28.002 0 0 $0
Torsten Rasmussen Direktor 11. Juni 2010 A 4.000 0 0 $0
Leslie L Iversen Direktor 11. Juni 2010 A 9.000 0 0 $0
Mary Ann Gray Direktor 11. Juni 2010 A 0 0 $0
Michael T Borer Direktor 11. Juni 2010 A 0 0 $0
Lester J Ph D Kaplan Direktor 11. Juni 2010 A 4.000 0 0 $0
Gordon M Binder Direktor 12. Juni 2009 A 14.364 0 0 $0
Alan G Walton Direktor 12. Juni 2009 A 25.979 0 0 $0
Martien Van Osch Direktor 10. Juni 2005 A 1.168.892 0 0 $0
GORDON CARL L Direktor 20. April 2005 A 774.006 0 0 $0
Mark C. Schneyer 6. August 2026 M 67.828 0 3 $-587.248
John Joseph Kaiser 20. Oktober 2008 A 0 0 $0

Insider aus SEC-Einreichungen Form 3/4/5; Netto = nur P/S aus offenen Märkten

Aktivisten & 5%+-Eigentümer 6 Beteiligungen

Investoren mit SEC Schedule 13D — wirtschaftliches Eigentum über 5% mit der Absicht, Einfluss auf den Emittenten zu nehmen (aktivistische Beteiligungen, Board-Kampagnen, M&A). Jede Zeile zeigt den zuletzt bekannten Stand der Position dieses Melders.

Anmelder Eingereicht Beteiligung Status Zweck Einreichung
Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC, Julian C. Baker, Felix J. Baker, FBB3 LLC ×14 Einreichungen 26. Februar 2026 25,40% Änderung SEC
Baker Bros. Advisors, LLC, Felix J. Baker, Julian C. Baker ×4 Einreichungen 6. Juni 2013 Erste Einreichung SEC
Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter 2. Mai 2005 Erste Einreichung SEC
Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter 2. Mai 2005 Erste Einreichung SEC
Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter 2. Mai 2005 Erste Einreichung SEC
Oxford Bioscience Partners IV L.P., mRNA Fund II L.P., OBP Management IV L.P., Jeffrey T. Barnes, Mark P. Carthy, Jonathan J. Fleming, Michael E. Lytton, Alan G. Walton 29. April 2005 Erste Einreichung Passive Anlage SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF-Besitz Gehalten von 77 ETFs

Gewichtung spiegelt nur direkte Aktienbestände (N-PORT) wider; gehebelte oder derivatbasierte Fonds können zusätzliche Swap-Exposure halten, die hier nicht angezeigt wird.

Fonds Gewicht Anteile Stand Quelle
IBRN · iShares Trust 4,89% 13.265 SH 8. August 2026 Täglich
PBE · Invesco Exchange-Traded Fund Trust 3,29% 407.914 SH 8. August 2026 Täglich
SBIO · ALPS ETF Trust 2,35% 175.740 NS 31. Mai 2026 N-PORT
PSCH · Invesco Exchange-Traded Fund Trust … 1,87% 109.972 SH 8. August 2026 Täglich
BBP · ETFis Series Trust I 1,32% 34.855 NS 30. April 2026 N-PORT
RZG · Invesco Exchange-Traded Fund Trust 1,25% 59.514 SH 8. August 2026 Täglich
LABU · Direxion Shares ETF Trust 0,85% 195.542 NS 30. April 2026 N-PORT
ROSC · Lattice Strategies Trust 0,56% 13.607 NS 30. April 2026 N-PORT
IJT · iShares Trust 0,40% 1.176.933 SH 8. August 2026 Täglich
OASC · Unified Series Trust 0,39% 15.269 NS 31. Mai 2026 N-PORT
IBB · iShares Trust 0,37% 1.239.145 SH 8. August 2026 Täglich
VIOG · VANGUARD ADMIRAL FUNDS 0,35% 150.827 SH 8. August 2026 Täglich
IBBQ · Invesco Exchange-Traded Fund Trust … 0,34% 9.317 SH 8. August 2026 Täglich
FNY · First Trust Exchange-Traded AlphaDE… 0,27% 61.606 NS 30. April 2026 N-PORT
BFOR · ALPS ETF Trust 0,24% 24.003 NS 31. Mai 2026 N-PORT
QVMS · Invesco Exchange-Traded Fund Trust … 0,23% 20.369 SH 8. August 2026 Täglich
IWO · iShares Trust 0,23% 1.166.817 SH 8. August 2026 Täglich
XJR · iShares Trust 0,23% 14.974 SH 8. August 2026 Täglich
GSSC · Goldman Sachs ETF Trust 0,20% 89.945 NS 31. Mai 2026 N-PORT
IJR · iShares Trust 0,20% 7.728.433 SH 8. August 2026 Täglich
VTWG · VANGUARD SCOTTSDALE FUNDS 0,19% 137.860 SH 8. August 2026 Täglich
BIB · ProShares Trust 0,19% 6.303 NS 31. Mai 2026 N-PORT
VIOO · VANGUARD ADMIRAL FUNDS 0,17% 443.221 SH 8. August 2026 Täglich
BKSE · BNY Mellon ETF Trust 0,17% 6.035 NS 30. April 2026 N-PORT
SMMV · iShares Trust 0,17% 17.063 SH 8. August 2026 Täglich
SMLF · iShares Trust 0,15% 219.745 SH 8. August 2026 Täglich
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0,15% 47.683 NS 30. April 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0,14% 137.072 SH 8. August 2026 Täglich
FNX · First Trust Exchange-Traded AlphaDE… 0,14% 81.552 NS 30. April 2026 N-PORT
SAA · ProShares Trust 0,12% 1.498 NS 31. Mai 2026 N-PORT
IWM · iShares Trust 0,12% 3.281.125 SH 8. August 2026 Täglich
ISCG · iShares Trust 0,11% 39.884 SH 8. August 2026 Täglich
VTWO · VANGUARD SCOTTSDALE FUNDS 0,10% 741.237 SH 8. August 2026 Täglich
RWJ · Invesco Exchange-Traded Fund Trust … 0,09% 66.331 SH 8. August 2026 Täglich
VBK · VANGUARD INDEX FUNDS 0,09% 1.699.377 SH 8. August 2026 Täglich
AVSC · AMERICAN CENTURY ETF TRUST 0,09% 115.210 NS 31. Mai 2026 N-PORT
DFAS · Dimensional ETF Trust 0,08% 526.641 NS 30. April 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0,08% 16.957 NS 30. April 2026 N-PORT
ITWO · ProShares Trust 0,07% 5.921 NS 31. Mai 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0,06% 599.784 NS 31. Mai 2026 N-PORT
ISCB · iShares Trust 0,06% 5.636 SH 8. August 2026 Täglich
FHLC · FIDELITY COVINGTON TRUST 0,04% 54.956 NS 30. April 2026 N-PORT
IEUS · iShares Trust 0,04% 7.411 SH 8. August 2026 Täglich
SMDX · Tidal Trust III 0,04% 2.306 NS 30. April 2026 N-PORT
OMFS · Invesco Exchange-Traded Self-Indexe… 0,04% 4.033 SH 8. August 2026 Täglich
UWM · ProShares Trust 0,04% 4.631 NS 31. Mai 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0,04% 1.457.036 SH 8. August 2026 Täglich
VB · VANGUARD INDEX FUNDS 0,04% 2.944.095 SH 8. August 2026 Täglich
PDN · Invesco Exchange-Traded Fund Trust … 0,04% 14.209 SH 8. August 2026 Täglich
VHT · VANGUARD WORLD FUND 0,04% 346.329 SH 8. August 2026 Täglich