DYN Dyne Therapeutics, Inc. - Common Stock
$26,41
Kurs · Aug 19, 2026
Fundamentaldaten per Jul 29, 2026
52W-Spanne
$12–$27
94% of range
Analystenbewertung
BUY
21 analysts
Kursziel
$39
+49% upside
P/E (TTM)
-7.6
ROE
-57.8%
Nettogewinnmarge
—
DYN Aktien-Snapshot Kurs, Marktkapitalisierung, P/E, EPS, ROE, Schulden/Eigenkapital, 52-Wochen-Spanne
Kurs
$26.41
Marktkapitalisierung
$4.36B
P/E (TTM)
-7.6
EPS (TTM)
$-3.47
Umsatz (TTM)
—
Dividendenrendite
—
ROE
-57.8%
Verschuldungsgrad
—
52W-Spanne
$12 – $27
DYN Aktienkurs-Chart Täglich OHLCV mit technischen Indikatoren — Schwenken, Zoom und Ansicht anpassen
Configure
10-Jahres-Performance Umsatz-, Nettoergebnis-, Margen- und EPS-Trends
Umsatz & Nettoergebnis
—
EPS
$-3.47
2021-12-31
→
2025-12-31
Freier Cashflow
$-405M
2020-12-31
→
2025-12-31
Margen
—
Bewertung P/E-, P/S-, P/B-, EV/EBITDA-Verhältnisse — ist die Aktie teuer oder günstig?
Kennzahl
5-Jahres-Trend
DYN
Peer-Median
P/E (TTM)
-7.6
13.2
P/B (K/B)
4.5
3.5
Price / FCF (Kurs / FCF)
-10.8
—
Rentabilität Brutto-, Betriebs- und Nettomargen; ROE, ROA, ROIC
Kennzahl
5-Jahres-Trend
DYN
Peer-Median
ROA
-47.5%
-42.2%
ROE
-57.8%
-52.8%
Finanzielle Gesundheit Verschuldung, Liquidität, Solvenz — Bilanzstärke
Kennzahl
5-Jahres-Trend
DYN
Peer-Median
Current Ratio (Liquiditätsgrad)
22.3
10.3
Quick Ratio
17.6
—
Wachstum Umsatz-, EPS- und Nettoergebniswachstum: YoY, 3-Jahres-CAGR, 5-Jahres-CAGR
Kennzahl
5-Jahres-Trend
DYN
Peer-Median
Kapitaleffizienz Umsatz pro Vermögenswert, Lagerumschlag, Forderungsumschlag
Kennzahl
5-Jahres-Trend
DYN
Peer-Median
DYN Analysten-Konsens Bullische und bärische Analystenmeinungen, 12-Monats-Kursziel, Aufwärtspotenzial
KAUF
21 Analysten
- Starker Kauf 7 33,3%
- Kauf 12 57,1%
- Halten 2 9,5%
- Verkauf 0 0,0%
- Starker Verkauf 0 0,0%
12-Monats-Kursziel
15 Analysten · 2026-08-15
Median
$40.00
Jetzt
$26.41
Tief
$17.00
Hoch
$50.00
Median-Ziel
$40.00
+51,5%
Mittelwert-Ziel
$39.40
+49,2%
Ergebnisverlauf EPS Ist vs. Schätzung, Überraschung %, Beat-Rate, nächstes Ergebnisdatum
Durchschn. Überraschung
-0.06%
| Zeitraum | EPS Actual | EPS est. | Überraschung |
|---|---|---|---|
| 30. Juni 2026 | $-1.08 | $-0.76 | -0.32% |
| 31. März 2026 | $-0.73 | $-0.78 | 0.05% |
| 31. Dezember 2025 | $-0.76 | $-0.78 | 0.02% |
| 30. September 2025 | $-0.76 | $-0.85 | 0.09% |
| 30. Juni 2025 | $-0.97 | $-0.96 | -0.01% |
| 31. März 2025 | $-1.05 | $-0.89 | -0.16% |
Peer-Vergleich (GICS-Subbranche) Wichtige Kennzahlen im Vergleich zu Branchenkollegen
| Ticker | Marktkapitalisierung | P/E | Umsatz Vj. | Nettomarge | ROE | Bruttogewinnmarge |
|---|---|---|---|---|---|---|
| DYN | $3.23B | -5.6 | — | — | -57.8% | — |
| CAI | $7.62B | -8.4 | 97.0% | -8.4% | -13.2% | — |
| PTCT | $6.19B | 9.8 | 114.5% | 39.4% | -331.5% | — |
| TVTX | $3.47B | -131.8 | 110.5% | -5.2% | -34.6% | — |
| ACAD | $4.55B | 11.6 | 11.9% | 36.5% | 38.1% | — |
| CELC | $4.81B | -26.3 | — | — | -244.3% | — |
| RLAY | $1.47B | -5.3 | 53.4% | -1800.6% | -44.9% | — |
| PBLS | — | — | — | — | — | — |
| TNGX | $1.20B | -10.2 | 48.3% | -162.8% | -42.2% | — |
Vollständige Fundamentaldaten Alle Kennzahlen nach Jahr — Gewinn- und Verlustrechnung, Bilanz, Cashflow
Gewinn- und Verlustrechnung 10
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| R&D Expense | $398M | $281M | $211M | $143M | $121M | $45M | $11M | |
| SG&A Expense | $70M | $62M | $31M | $28M | $29M | $13M | $3M | |
| Operating Expenses | $468M | $344M | $242M | $171M | $150M | $59M | $14M | |
| Operating Income | $-468M | $-344M | $-242M | $-171M | $-150M | $-59M | $-14M | |
| Other Non-op | $22M | $26M | $6M | $3M | $734.0K | $-790.0K | $-1M | |
| Income Tax | $0 | $0 | $0 | · | · | · | · | |
| Net Income | $-446M | $-317M | $-236M | $-168M | $-149M | $-59M | $-15M | |
| EPS (Basic) | $-3.47 | $-3.37 | $-3.95 | $-3.23 | $-2.93 | · | · | |
| EPS (Diluted) | $-3.47 | $-3.37 | $-3.95 | $-3.23 | $-2.93 | · | · | |
| EBITDA | $-466M | $-342M | $-240M | $-169M | $-149M | $-58M | · |
Bilanz 20
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $893M | $435M | $122M | $172M | $201M | $301M | $15M | |
| Prepaid Expense | $16M | $17M | $6M | $10M | $6M | $4M | $127.0K | |
| Current Assets | $1.13B | $659M | $129M | $266M | $382M | $349M | $15M | |
| PP&E (Net) | $24M | $5M | $5M | $6M | $5M | $2M | $1M | |
| PP&E (Gross) | $33M | $12M | $10M | $10M | $7M | $3M | $2M | |
| Accum. Depreciation | $9M | $7M | $5M | $4M | $2M | $995.0K | $295.0K | |
| Other Non-current Assets | · | · | · | · | · | · | $191.0K | |
| Total Assets | $1.19B | $691M | $165M | $306M | $426M | $353M | $16M | |
| Accounts Payable | $8M | $7M | $23M | $5M | $4M | $3M | $1M | |
| Current Liabilities | $51M | $42M | $51M | $28M | $29M | $11M | $2M | |
| Capital Leases | $15M | $19M | $23M | $26M | $29M | $0 | · | |
| Total Liabilities | $215M | $61M | $74M | $54M | $57M | $11M | $2M | |
| Long-term Debt | $149M | $0 | · | · | · | · | · | |
| Common Stock | $16.0K | $10.0K | $6.0K | $6.0K | $6.0K | $5.0K | $1.0K | |
| Paid-in Capital | $2.37B | $1.58B | $724M | $650M | $597M | $422M | $6M | |
| Retained Earnings | $-1.40B | $-950M | $-633M | $-397M | $-228M | $-79M | $-20M | |
| AOCI | $475.0K | $6.0K | $0 | $-571.0K | $-269.0K | $-27.0K | · | |
| Stockholders' Equity | $972M | $630M | $91M | $252M | $368M | $342M | $14M | |
| Liabilities + Equity | $1.19B | $691M | $165M | $306M | $426M | $353M | $16M | |
| Shares Outstanding | 164,950,540 | 102,318,629 | 61,468,743 | 55,636,505 | 51,569,381 | 45,076,574 | 2,586,535 |
Cashflow 13
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| D&A | $2M | $2M | $2M | $2M | $1M | $700.0K | $271.0K | |
| Stock-based Comp | $46M | $46M | $20M | $15M | $18M | $7M | $26.0K | |
| Other Non-cash | $-5M | $-22M | $26M | $-2M | $11M | $6M | · | |
| Operating Cash Flow | $-403M | $-292M | $-188M | $-154M | $-120M | $-47M | $-12M | |
| CapEx | $2M | $2M | $729.0K | $3M | $4M | $1M | $2M | |
| Investing Cash Flow | $-29M | $-204M | $83M | $87M | $-138M | $-46M | $-2M | |
| Debt Issued | $148M | $0 | $0 | · | · | $10M | · | |
| Net Debt Issued | $148M | · | · | · | · | $10M | · | |
| Stock Issued | $141M | $98M | $52M | $37M | · | · | · | |
| Net Stock Activity | $141M | $98M | · | · | · | · | · | |
| Financing Cash Flow | $890M | $810M | $54M | $37M | $158M | $381M | $20M | |
| Net Change in Cash | $458M | $313M | $-51M | $-29M | $-100M | $289M | $7M | |
| Free Cash Flow | $-405M | $-295M | $-189M | $-157M | $-123M | $-48M | · |
Rentabilität 2
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -47.5% | -74.1% | -100.1% | -45.9% | -38.3% | -32.1% | · | |
| ROE | -57.8% | -47.5% | -193.9% | -67.0% | -38.2% | -16.8% | · |
Liquidität & Solvenz 2
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 22.3 | 15.6 | 2.5 | 9.5 | 13.3 | 31.8 | · | |
| Quick Ratio | 17.6 | 10.3 | 2.4 | 6.1 | 7.0 | 27.4 | · |
Bewertung (TTM) 8
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-446M | $-317M | $-236M | $-168M | $-149M | $-59M | · | |
| Market Cap | $3.23B | $2.41B | $818M | $645M | $613M | $947M | · | |
| P/E | -5.6 | -7.0 | -3.4 | -3.6 | -4.1 | · | · | |
| P/B | 3.3 | 3.8 | 9.0 | 2.6 | 1.7 | 2.8 | · | |
| P / Tangible Book | 3.3 | 3.8 | 9.0 | 2.6 | 1.7 | 2.8 | · | |
| P / Cash Flow | -8.0 | -8.2 | -4.3 | -4.2 | -5.1 | -20.4 | · | |
| P / FCF | -8.0 | -8.2 | -4.3 | -4.1 | -5.0 | -19.9 | · | |
| Earnings Yield | -17.7% | -14.3% | -29.7% | -27.9% | -24.6% | · | · |
Gewinn- und Verlustrechnung 10
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $152M | $101M | $95M | $97M | $99M | $106M | $82M | $93M | $62M | $45M | $55M | $59M | $38M | $35M | $47M | $28M | |
| SG&A Expense | $29M | $24M | $21M | $17M | $17M | $16M | $15M | $13M | $10M | $25M | $7M | $8M | $8M | $8M | $6M | $8M | |
| Operating Expenses | $182M | $125M | $116M | $114M | $116M | $122M | $97M | $106M | $72M | $69M | $62M | $67M | $45M | $42M | $53M | $36M | |
| Operating Income | $-182M | $-125M | $-116M | $-114M | $-116M | $-122M | $-97M | $-106M | $-72M | $-69M | $-62M | $-67M | $-45M | $-42M | $-53M | $-36M | |
| Interest Expense | · | · | · | $3M | $94.0K | · | · | $0 | · | · | · | · | · | · | · | · | |
| Other Non-op | $3M | $4M | $4M | $6M | $5M | $7M | $8M | $9M | $7M | $4M | $2M | $2M | $1M | $894.0K | $451.0K | $200.0K | |
| Net Income | $-179M | $-121M | $-112M | $-108M | $-111M | $-115M | $-90M | $-97M | $-65M | $-66M | $-60M | $-65M | $-44M | $-41M | $-52M | $-36M | |
| EPS (Basic) | $-1.08 | $-0.73 | $-0.69 | $-0.76 | $-0.97 | $-1.05 | $-0.90 | $-0.96 | $-0.70 | $-0.81 | $-0.99 | $-1.08 | $-0.78 | $-0.80 | $-1.01 | $-0.69 | |
| EPS (Diluted) | $-1.08 | $-0.73 | $-0.69 | $-0.76 | $-0.97 | $-1.05 | $-0.90 | $-0.96 | $-0.70 | $-0.81 | $-0.99 | $-1.08 | $-0.78 | $-0.80 | $-1.01 | $-0.69 | |
| EBITDA | $-181M | $-125M | · | $-113M | $-115M | $-122M | · | $-105M | $-72M | $-69M | $-62M | $-66M | $-45M | $-42M | $-52M | $-35M |
Bilanz 19
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $676M | $753M | $893M | $574M | $485M | $472M | $435M | $532M | $608M | $272M | $130M | $168M | $181M | $145M | $136M | $148M | |
| Prepaid Expense | $39M | $49M | $16M | $14M | $14M | $12M | $17M | $13M | $13M | $35M | $10M | $5M | $11M | $10M | $6M | $21M | |
| Current Assets | $938M | $1.02B | $1.13B | $806M | $698M | $690M | $659M | $736M | $792M | $488M | $168M | $213M | $249M | $258M | $298M | $344M | |
| PP&E (Net) | $25M | $24M | $24M | $24M | $6M | $6M | $5M | $5M | $5M | $5M | $5M | $5M | $6M | $6M | $5M | $6M | |
| PP&E (Gross) | $34M | $33M | $33M | $32M | $13M | $13M | $12M | $11M | $11M | $10M | $10M | $10M | $10M | $9M | $8M | $8M | |
| Accum. Depreciation | $10M | $9M | $9M | $8M | $8M | $7M | $7M | $7M | $6M | $6M | $5M | $4M | $4M | $3M | $3M | $2M | |
| Total Assets | $994M | $1.08B | $1.19B | $867M | $729M | $721M | $691M | $769M | $826M | $522M | $205M | $251M | $289M | $300M | $340M | $388M | |
| Accounts Payable | $12M | $11M | $8M | $12M | $14M | $7M | $7M | $6M | $2M | $7M | $4M | $3M | $9M | $919.0K | $7M | $5M | |
| Current Liabilities | $78M | $51M | $51M | $60M | $41M | $34M | $42M | $43M | $30M | $22M | $30M | $20M | $22M | $23M | $26M | $23M | |
| Capital Leases | $15M | $14M | $15M | $16M | $17M | $18M | $19M | $20M | $21M | $22M | $24M | $24M | $25M | $27M | $27M | $28M | |
| Total Liabilities | $292M | $215M | $215M | $175M | $158M | $52M | $61M | $63M | $51M | $44M | $53M | $45M | $47M | $50M | $53M | $51M | |
| Long-term Debt | $199M | $149M | $149M | $99M | $99M | · | $0 | · | · | · | · | · | · | · | · | · | |
| Common Stock | $16.0K | $16.0K | $16.0K | $14.0K | $11.0K | $11.0K | $10.0K | $10.0K | $10.0K | $9.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | |
| Paid-in Capital | $2.40B | $2.38B | $2.37B | $1.98B | $1.75B | $1.73B | $1.58B | $1.57B | $1.54B | $1.18B | $718M | $713M | $683M | $608M | $605M | $601M | |
| Retained Earnings | $-1.70B | $-1.52B | $-1.40B | $-1.28B | $-1.18B | $-1.07B | $-950M | $-860M | $-763M | $-698M | $-566M | $-506M | $-441M | $-358M | $-316M | $-264M | |
| AOCI | $-353.0K | $-137.0K | $475.0K | $496.0K | $252.0K | $241.0K | $6.0K | $478.0K | $-240.0K | $-132.0K | $-13.0K | $-56.0K | $-203.0K | $-983.0K | $-1M | $-930.0K | |
| Stockholders' Equity | $702M | $865M | $972M | $692M | $571M | $669M | $630M | $706M | $775M | $478M | $152M | $207M | $242M | $250M | $287M | $336M | |
| Liabilities + Equity | $994M | $1.08B | $1.19B | $867M | $729M | $721M | $691M | $769M | $826M | $522M | $205M | $251M | $289M | $300M | $340M | $388M | |
| Shares Outstanding | 165,670,880 | 165,201,329 | 164,950,540 | 142,613,248 | 114,338,610 | 113,633,782 | 102,318,629 | 101,753,378 | 100,119,518 | 87,089,649 | 61,322,283 | 61,013,986 | 58,305,480 | 51,906,773 | 51,734,361 | 51,649,423 |
Cashflow 12
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $600.0K | $550.0K | $547.0K | $500.0K | $500.0K | $502.0K | $487.0K | $400.0K | $400.0K | $386.0K | $400.0K | $400.0K | $412.0K | $400.0K | $500.0K | $425.0K | |
| Stock-based Comp | $15M | $13M | $11M | $11M | $11M | $13M | $10M | $9M | $7M | $20M | $5M | $5M | $5M | $4M | $3M | $4M | |
| Other Non-cash | · | $-38M | · | · | · | $-4M | · | · | · | $-33M | · | · | $-8M | · | · | $-20M | |
| Operating Cash Flow | $-130M | $-145M | $-112M | $-91M | $-95M | $-106M | $-84M | $-75M | $-55M | $-79M | $-51M | $-56M | $-47M | $-43M | $-31M | $-51M | |
| CapEx | $2M | $221.0K | $484.0K | $395.0K | $60.0K | $981.0K | $1M | $253.0K | $857.0K | $191.0K | $167.0K | $250.0K | $230.0K | $886.0K | $261.0K | $1M | |
| Investing Cash Flow | $-5M | $-2M | $982.0K | $-38M | $7M | $1M | $-16M | $-19M | $11M | $-180M | $13M | $17M | $27M | $52M | $18M | $-2M | |
| Debt Issued | · | · | $49M | $0 | · | · | $0 | $0 | · | · | · | · | · | · | · | · | |
| Stock Issued | $0 | $0 | $0 | $0 | $0 | $141M | $0 | $0 | $24M | $74M | $0 | $24M | $28M | · | · | · | |
| Net Stock Activity | · | $0 | · | · | · | $141M | · | · | · | $74M | · | · | · | · | · | · | |
| Financing Cash Flow | $58M | $7M | $431M | $217M | $101M | $141M | $4M | $18M | $380M | $408M | $454.0K | $25M | $29M | $70.0K | $99.0K | $18.0K | |
| Net Change in Cash | $-77M | $-140M | $320M | $89M | $13M | $37M | $-97M | $-76M | $336M | $150M | $-37M | $-14M | $9M | $9M | $-12M | $-53M | |
| Free Cash Flow | · | $-145M | · | · | · | $-107M | · | · | · | $-79M | · | · | $-47M | · | · | $-52M |
Rentabilität 2
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -20.7% | -13.4% | · | -13.2% | -14.3% | -18.6% | · | -19.9% | -12.1% | -16.2% | -23.8% | -21.9% | -13.1% | -10.8% | -13.0% | -8.1% | |
| ROE | -28.0% | -15.8% | · | -15.5% | -16.5% | -20.1% | · | -22.7% | -13.3% | -18.2% | -30.0% | -26.3% | -15.3% | -12.5% | -14.1% | -8.7% |
Liquidität & Solvenz 3
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 12.0 | 19.9 | · | 13.5 | 16.8 | 20.4 | · | 17.0 | 26.6 | 21.8 | 5.7 | 10.5 | 11.5 | 11.1 | 11.6 | 14.8 | |
| Quick Ratio | 8.7 | 14.7 | · | 9.6 | 11.7 | 13.9 | · | 12.3 | 20.4 | 12.2 | 4.4 | 8.3 | 8.4 | 6.2 | 5.3 | 6.4 | |
| Interest Coverage | · | · | · | -39.2 | -1231.8 | · | · | · | · | · | · | · | · | · | · | · |
Bewertung (TTM) 8
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-518M | $-455M | · | $-431M | $-388M | $-343M | · | $-288M | $-256M | $-235M | $-211M | $-203M | $-173M | $-172M | $-160M | $-133M | |
| Market Cap | $3.68B | $3.00B | · | $1.80B | $1.09B | $1.19B | · | $3.65B | $3.53B | $2.47B | $549M | $686M | $672M | $659M | $355M | $498M | |
| P/E | -6.3 | -5.2 | · | -3.4 | -2.6 | -3.0 | · | -10.4 | -9.9 | -7.8 | -2.5 | -3.1 | -3.5 | -3.8 | -2.2 | · | |
| P/B | 5.2 | 3.5 | · | 2.6 | 1.9 | 1.8 | · | 5.2 | 4.6 | 5.2 | 3.6 | 3.3 | 2.8 | 2.6 | 1.2 | 1.5 | |
| P / Tangible Book | 5.2 | 3.5 | · | 2.6 | 1.9 | 1.8 | · | 5.2 | 4.6 | 5.2 | 3.6 | 3.3 | 2.8 | 2.6 | 1.2 | 1.5 | |
| P / Cash Flow | · | -20.7 | · | · | · | -11.2 | · | · | · | -31.5 | · | · | -14.3 | · | · | -9.8 | |
| P / FCF | · | -20.6 | · | · | · | -11.1 | · | · | · | -31.4 | · | · | -14.2 | · | · | -9.5 | |
| Earnings Yield | -15.9% | -19.4% | · | -29.6% | -38.7% | -33.7% | · | -9.6% | -10.1% | -12.9% | -40.7% | -32.6% | -28.5% | -26.2% | -45.3% | · |
Finanzberichte Gewinn- und Verlustrechnung, Bilanz, Cashflow — jährlich, letzte 5 Jahre
Gewinn- und Verlustrechnung
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Nettoergebnis | $-446M | $-317M | $-236M | $-168M | $-149M |
| Verwässerte EPS | $-3.47 | $-3.37 | $-3.95 | $-3.23 | $-2.93 |
Bilanz
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Liquiditätsgrad | 22.3 | 15.6 | 2.5 | 9.5 | 13.3 |
| Quick Ratio | 17.6 | 10.3 | 2.4 | 6.1 | 7.0 |
Cashflow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Freier Cashflow | $-405M | $-295M | $-189M | $-157M | $-123M |
Neueste Nachrichten Aktuelle Schlagzeilen über dieses Unternehmen
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Institutionelle Eigentümer (13F) 261 Einreicher · $2.5B gesamt · Stand 30. Juni 2026
Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.
Institutionelle Aktivität — Q2 2026 vs. Vorquartal
| Neue Positionen | Geschlossene Positionen | Erhöht | Abgenommen | Nettoveränderung der Aktien |
|---|---|---|---|---|
| 54 (+19 vs. Vorquartal) | 27 (-14 vs. Vorquartal) | 87 (-11 vs. Vorquartal) | 70 (+7 vs. Vorquartal) | +15.5M |
Verglichen mit Q1 2026. SEC-Formular 13F-Einreichungen sind innerhalb von 45 Tagen nach Quartalsende fällig, zuzüglich einer kurzen Pufferzeit für verspätete Einreicher — Quartale, die noch in diesem Fenster liegen, werden zugunsten des letzten vollständig berichteten Paares übersprungen.
| Institution | Wert | Aktien | % der verfolgten 13F | Typ |
|---|---|---|---|---|
| STATE STREET CORP | $165.648.021 | 7.458.263 | 6,74% | Aktien |
| FMR LLC | $160.201.907 | 7.213.053 | 6,52% | Aktien |
| Orbis Allan Gray Ltd | $155.111.575 | 6.983.862 | 6,31% | Aktien |
| Atlas Venture Life Science Advisors, LLC | $151.030.199 | 6.800.099 | 6,14% | Aktien |
| VANGUARD CAPITAL MANAGEMENT LLC | $140.166.621 | 6.310.969 | 5,70% | Aktien |
| TCG Crossover Management, LLC | $102.502.348 | 4.615.144 | 4,17% | Aktien |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $89.915.586 | 4.048.428 | 3,66% | Aktien |
| Vestal Point Capital, LP | $74.958.750 | 3.375.000 | 3,05% | Aktien |
| ORBIMED ADVISORS LLC | $71.864.542 | 3.235.684 | 2,92% | Aktien |
| GEODE CAPITAL MANAGEMENT, LLC | $71.309.878 | 3.209.934 | 2,90% | Aktien |
| Frazier Life Sciences Management, L.P. | $70.029.951 | 3.153.082 | 2,85% | Aktien |
| ARMISTICE CAPITAL, LLC | $68.567.289 | 3.087.226 | 2,79% | Aktien |
| PERCEPTIVE ADVISORS LLC | $59.727.909 | 2.689.235 | 2,43% | Aktien |
| Logos Global Management LP | $56.635.500 | 2.550.000 | 2,30% | Aktien |
| Venrock Adviser, LLC | $48.282.608 | 2.173.913 | 1,96% | Aktien |
| Siren, L.L.C. | $47.287.866 | 2.129.125 | 1,92% | Aktien |
| MPM BIOIMPACT LLC | $42.689.686 | 1.922.093 | 1,74% | Aktien |
| GOLDMAN SACHS GROUP INC | $41.625.071 | 1.874.159 | 1,69% | Aktien |
| DIMENSIONAL FUND ADVISORS LP | $40.865.556 | 1.839.962 | 1,66% | Aktien |
| Sofinnova Investments, Inc. | $36.832.709 | 1.658.384 | 1,50% | Aktien |
| Palo Alto Investors LP | $36.591.441 | 1.647.521 | 1,49% | Aktien |
| Vivo Capital, LLC | $34.591.320 | 1.557.466 | 1,41% | Aktien |
| Aberdeen Group plc | $34.190.829 | 1.539.434 | 1,39% | Aktien |
| Deep Track Capital, LP | $33.315.000 | 1.500.000 | 1,35% | Aktien |
| BANK OF AMERICA CORP /DE/ | $31.725.719 | 1.428.443 | 1,29% | Aktien |
| FCPM III SERVICES B.V. | $31.679.678 | 1.426.370 | 1,29% | Aktien |
| Polar Capital Holdings Plc | $28.580.072 | 1.286.811 | 1,16% | Aktien |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $26.700.929 | 1.202.203 | 1,09% | Aktien |
| CITADEL ADVISORS LLC | $25.407.307 | 1.143.958 | 1,03% | Aktien |
| Saturn V Capital Management LP | $23.486.920 | 1.057.493 | 0,96% | Aktien |
| VANGUARD FIDUCIARY TRUST CO | $21.964.557 | 988.949 | 0,89% | Aktien |
| NOVO HOLDINGS A/S | $21.330.351 | 960.394 | 0,87% | Aktien |
| Rock Springs Capital Management LP | $20.925.240 | 942.154 | 0,85% | Aktien |
| BRAIDWELL LP | $20.468.692 | 921.598 | 0,83% | Aktien |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $19.414.605 | 874.138 | 0,79% | Aktien |
| BAKER BROS. ADVISORS LP | $18.066.702 | 813.449 | 0,73% | Aktien |
| SAMLYN CAPITAL, LLC | $14.875.658 | 669.773 | 0,61% | Aktien |
| Artisan Partners Limited Partnership | $14.653.847 | 659.786 | 0,60% | Aktien |
| TD Asset Management Inc | $12.173.568 | 548.112 | 0,50% | Aktien |
| ALGERT GLOBAL LLC | $11.244.323 | 506.273 | 0,46% | Aktien |
| MILLENNIUM MANAGEMENT LLC | $9.591.389 | 431.850 | 0,39% | Aktien |
| Clearbridge Investments, LLC | $9.220.070 | 415.131 | 0,37% | Aktien |
| ArrowMark Colorado Holdings LLC | $8.822.278 | 397.221 | 0,36% | Aktien |
| MPM ASSET MANAGEMENT LLC | $8.632.056 | 682.376 | 0,35% | Aktien |
| WASATCH ADVISORS LP | $8.043.701 | 443.668 | 0,33% | Aktien |
| RENAISSANCE TECHNOLOGIES LLC | $8.008.304 | 360.572 | 0,33% | Aktien |
| Tetragon Partners GP Ltd | $7.921.352 | 356.657 | 0,32% | Aktien |
| NEW YORK STATE COMMON RETIREMENT FUND | $7.905.716 | 355.953 | 0,32% | Aktien |
| Granahan Investment Management, LLC | $7.519.529 | 338.565 | 0,31% | Aktien |
| University of Wisconsin Foundation | $6.964.146 | 313.559 | 0,28% | Aktien |
| MOORE CAPITAL MANAGEMENT, LP | $6.791.685 | 305.794 | 0,28% | Aktien |
| Squarepoint Ops LLC | $6.664.644 | 300.074 | 0,27% | Aktien |
| Fisher Asset Management, LLC | $6.629.795 | 298.505 | 0,27% | Aktien |
| AMERIPRISE FINANCIAL INC | $6.625.622 | 298.317 | 0,27% | Aktien |
| RAYMOND JAMES FINANCIAL INC | $6.468.951 | 291.263 | 0,26% | Aktien |
| Ensign Peak Advisors, Inc | $6.434.903 | 289.730 | 0,26% | Aktien |
| Alyeska Investment Group, L.P. | $5.447.624 | 245.278 | 0,22% | Aktien |
| Catalio Capital Management, LP | $5.439.873 | 244.929 | 0,22% | Aktien |
| Swiss National Bank | $5.152.720 | 232.000 | 0,21% | Aktien |
| SPHERA FUNDS MANAGEMENT LTD. | $4.432.983 | 199.594 | 0,18% | Aktien |
| SummitTX Capital, L.P. | $4.323.021 | 194.643 | 0,18% | Aktien |
| RHUMBLINE ADVISERS | $4.082.158 | 183.799 | 0,17% | Aktien |
| CITIGROUP INC | $3.998.733 | 180.042 | 0,16% | Aktien |
| HighVista Strategies LLC | $3.819.254 | 171.961 | 0,16% | Aktien |
| ALPS ADVISORS INC | $3.710.891 | 167.082 | 0,15% | Aktien |
| Y-Intercept (Hong Kong) Ltd | $3.469.269 | 156.203 | 0,14% | Aktien |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $3.467.781 | 156.136 | 0,14% | Aktien |
| AXXCESS WEALTH MANAGEMENT, LLC | $3.448.547 | 155.270 | 0,14% | Aktien |
| Darwin Wealth Management, LLC | $3.448.546 | 155.270 | 0,14% | Aktien |
| Aegis Wealth Management LLC | $3.332.166 | 150.030 | 0,14% | Aktien |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $3.331.500 | 150.000 | 0,14% | Aktien |
| Woodline Partners LP | $3.317.907 | 149.388 | 0,13% | Aktien |
| BlackRock, Inc. | $3.223.182 | 145.123 | 0,13% | Aktien |
| Bank of New York Mellon Corp | $3.129.789 | 140.918 | 0,13% | Aktien |
| ALLIANCEBERNSTEIN L.P. | $3.119.810 | 172.080 | 0,13% | Aktien |
| Schonfeld Strategic Advisors LLC | $2.992.841 | 134.752 | 0,12% | Aktien |
| XTX Topco Ltd | $2.793.707 | 125.786 | 0,11% | Aktien |
| Jain Global LLC | $2.583.934 | 116.341 | 0,11% | Aktien |
| Rafferty Asset Management, LLC | $2.556.415 | 115.102 | 0,10% | Aktien |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2.532.090 | 139.663 | 0,10% | Aktien |
| MORGAN STANLEY | $2.460.571 | 110.786 | 0,10% | Aktien |
| AXA Investment Managers S.A. | $2.064.872 | 163.231 | 0,08% | Aktien |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | $1.933.798 | 87.069 | 0,08% | Aktien |
| JANUS HENDERSON GROUP PLC | $1.810.516 | 99.863 | 0,07% | Aktien |
| VANGUARD ASSET MANAGEMENT, Ltd | $1.804.296 | 81.238 | 0,07% | Aktien |
| MetLife Investment Management, LLC | $1.771.803 | 79.775 | 0,07% | Aktien |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1.746.195 | 78.622 | 0,07% | Aktien |
| FIFTH THIRD BANCORP | $1.684.826 | 75.859 | 0,07% | Aktien |
| CIBC WORLD MARKET INC. | $1.683.140 | 75.783 | 0,07% | Aktien |
| STATE OF WISCONSIN INVESTMENT BOARD | $1.548.081 | 69.702 | 0,06% | Aktien |
| ENVESTNET ASSET MANAGEMENT INC | $1.478.808 | 66.583 | 0,06% | Aktien |
| VANGUARD GROUP INC | $1.433.904 | 73.308 | 0,06% | Aktien |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1.395.321 | 62.824 | 0,06% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.390.346 | 62.600 | 0,06% | Verkaufsoption |
| JANE STREET GROUP, LLC | $1.377.020 | 62.000 | 0,06% | Verkaufsoption |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $1.309.213 | 58.947 | 0,05% | Aktien |
| PROFUND ADVISORS LLC | $1.306.170 | 58.810 | 0,05% | Aktien |
| Invesco Ltd. | $1.212.555 | 54.595 | 0,05% | Aktien |
| VICTORY CAPITAL MANAGEMENT INC | $1.210.400 | 54.498 | 0,05% | Aktien |
| Vanguard Global Advisers, LLC | $1.202.383 | 54.137 | 0,05% | Aktien |
Unternehmensinsider 26 Insider · 7 Führungskräfte · 10 Direktoren
| Insider | Rolle | Letzte Aktivität | Gehaltene Aktien | Käufe 12m | Verkäufe 12m | Netto 12m |
|---|---|---|---|---|---|---|
| Joshua T Brumm | CEO & President | 11. März 2024 M | 537.998 | 0 | 0 | $0 |
| Susanna Gatti High | Chief Operating Officer | 18. September 2024 S | 131.636 | 0 | 0 | $0 |
| Oxana Beskrovnaya | Chief Scientific Officer | 11. März 2025 S | 195.840 | 0 | 0 | $0 |
| Richard William Scalzo | SVP, Head of Finance & Admin. | 11. März 2025 S | 122.330 | 0 | 0 | $0 |
| Wildon Farwell | Chief Medical Officer | 19. August 2024 S | 143.222 | 0 | 0 | $0 |
| Jonathan Mcneill | Chief Business Officer | 19. August 2024 S | 132.106 | 0 | 0 | $0 |
| Romesh Subramanian | Chief Scientific Officer | 16. September 2020 A | 566.249 | 0 | 0 | $0 |
| Dirk Kersten | Direktor | 27. Juli 2026 S | 3.586.796 | 0 | 19 | $-38.570.974 |
| Barry E Greene | Direktor | 22. Juni 2026 A | — | 0 | 0 | $0 |
| Carlo Incerti | Direktor | 5. Juni 2026 A | 0 | 0 | 0 | $0 |
| Catherine Stehman-Breen | Direktor | 5. Juni 2026 A | 115.713 | 0 | 0 | $0 |
| David Charles Lubner | Direktor | 5. Juni 2026 A | 0 | 0 | 0 | $0 |
| Brian S Posner | Direktor | 5. Juni 2026 A | 24.500 | 7 | 0 | $274.840 |
| Edward Hurwitz | Direktor | 5. Juni 2026 A | 91.081 | 0 | 0 | $0 |
| Vikram Karnani | Direktor | 22. Dezember 2025 A | — | 0 | 0 | $0 |
| Lawrence Otto Klein | Direktor | 5. Juli 2022 A | 10.725 | 0 | 0 | $0 |
| Atlas Venture Fund XI, L.P. | 10%-Eigentümer | 13. Juli 2021 J | 7.326.117 | 0 | 0 | $0 |
| CureDuchenne Ventures, LLC | 10%-Eigentümer | 21. September 2020 C | 602.972 | 0 | 0 | $0 |
| Forbion Capital Fund IV Cooperatief U.A. | 10%-Eigentümer | 21. September 2020 C | 6.131.079 | 0 | 0 | $0 |
| Logos Global Management LP | 10%-Eigentümer | 21. September 2020 C | 1.504.392 | 0 | 0 | $0 |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | 10%-Eigentümer | 21. September 2020 C | 1.608.785 | 0 | 0 | $0 |
| Jason P Rhodes | — | 14. August 2026 S | 428.946 | 0 | 31 | $-99.402.433 |
| Johanna Friedl-Naderer | — | 13. August 2026 S | 153.982 | 0 | 7 | $-31.766 |
| Douglas Kerr | — | 13. August 2026 S | 167.599 | 0 | 7 | $-176.412 |
| Erick Lucera | — | 13. August 2026 S | 119.766 | 0 | 4 | $-228.675 |
| John Cox | — | 13. August 2026 S | 363.165 | 0 | 5 | $-336.865 |
Insider aus SEC-Einreichungen Form 3/4/5; Netto = nur P/S aus offenen Märkten
Aktivisten & 5%+-Eigentümer 1 Beteiligung
Investoren mit SEC Schedule 13D — wirtschaftliches Eigentum über 5% mit der Absicht, Einfluss auf den Emittenten zu nehmen (aktivistische Beteiligungen, Board-Kampagnen, M&A). Jede Zeile zeigt den zuletzt bekannten Stand der Position dieses Melders.
| Anmelder | Eingereicht | Beteiligung | Status | Zweck | Einreichung |
|---|---|---|---|---|---|
| Vida Ventures II, LLC, Vida Ventures II-A, LLC, VV Manager II, LLC ×2 Einreichungen | 10. Februar 2023 | — | Erste Einreichung | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF-Besitz Gehalten von 52 ETFs
Gewichtung spiegelt nur direkte Aktienbestände (N-PORT) wider; gehebelte oder derivatbasierte Fonds können zusätzliche Swap-Exposure halten, die hier nicht angezeigt wird.
| Fonds | Gewicht | Anteile | Stand | Quelle |
|---|---|---|---|---|
| IBRN · iShares Trust | 3,47% | 10.352 SH | 8. August 2026 | Täglich |
| BBC · ETFis Series Trust I | 0,67% | 14.322 NS | 30. April 2026 | N-PORT |
| JDOC · J.P. Morgan Exchange-Traded Fund Tr… | 0,67% | 4.266 NS | 30. April 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,67% | 196.941 NS | 30. April 2026 | N-PORT |
| IBB · iShares Trust | 0,30% | 1.099.711 SH | 8. August 2026 | Täglich |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,30% | 8.997 SH | 8. August 2026 | Täglich |
| ESSC · Strategy Shares | 0,18% | 2.581 NS | 30. April 2026 | N-PORT |
| IWN · iShares Trust | 0,16% | 919.017 SH | 8. August 2026 | Täglich |
| BIB · ProShares Trust | 0,16% | 6.087 NS | 31. Mai 2026 | N-PORT |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,13% | 77.375 SH | 8. August 2026 | Täglich |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,12% | 51.630 NS | 30. April 2026 | N-PORT |
| IWM · iShares Trust | 0,12% | 3.833.065 SH | 8. August 2026 | Täglich |
| BKSE · BNY Mellon ETF Trust | 0,10% | 4.423 NS | 30. April 2026 | N-PORT |
| ISCG · iShares Trust | 0,09% | 36.532 SH | 8. August 2026 | Täglich |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,09% | 784.894 SH | 8. August 2026 | Täglich |
| IWO · iShares Trust | 0,08% | 463.505 SH | 8. August 2026 | Täglich |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,08% | 82.893 SH | 8. August 2026 | Täglich |
| ESML · iShares Trust | 0,08% | 84.297 SH | 8. August 2026 | Täglich |
| RSSL · Global X Funds | 0,07% | 57.752 NS | 30. April 2026 | N-PORT |
| ITWO · ProShares Trust | 0,06% | 6.271 NS | 31. Mai 2026 | N-PORT |
| ISCB · iShares Trust | 0,06% | 6.733 SH | 8. August 2026 | Täglich |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,06% | 50.849 SH | 8. August 2026 | Täglich |
| SCHA · SCHWAB STRATEGIC TRUST | 0,06% | 688.953 NS | 31. Mai 2026 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0,05% | 47.064 SH | 8. August 2026 | Täglich |
| DFAS · Dimensional ETF Trust | 0,05% | 390.218 NS | 30. April 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,04% | 1.689.620 SH | 8. August 2026 | Täglich |
| VHT · VANGUARD WORLD FUND | 0,04% | 347.244 SH | 8. August 2026 | Täglich |
| ISCV · iShares Trust | 0,04% | 10.732 SH | 8. August 2026 | Täglich |
| UWM · ProShares Trust | 0,04% | 4.905 NS | 31. Mai 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,03% | 53.716 NS | 30. April 2026 | N-PORT |
| WSML · iShares Trust | 0,03% | 8.466 SH | 8. August 2026 | Täglich |
| VBR · VANGUARD INDEX FUNDS | 0,03% | 1.020.875 SH | 8. August 2026 | Täglich |
| URTY · ProShares Trust | 0,03% | 4.964 NS | 31. Mai 2026 | N-PORT |
| TILT · FlexShares Trust | 0,02% | 25.564 NS | 30. April 2026 | N-PORT |
| VB · VANGUARD INDEX FUNDS | 0,02% | 1.607.020 SH | 8. August 2026 | Täglich |
| SMLF · iShares Trust | 0,02% | 32.751 SH | 8. August 2026 | Täglich |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 4.701 NS | 31. Mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,01% | 125 NS | 31. Mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 44.010 NS | 31. Mai 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,01% | 11.272 NS | 31. Mai 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,01% | 9.076 NS | 30. April 2026 | N-PORT |
| ITOT · iShares Trust | 0,01% | 199.812 SH | 8. August 2026 | Täglich |
| IWV · iShares Trust | 0,01% | 38.879 SH | 8. August 2026 | Täglich |
| DFAC · Dimensional ETF Trust | 0,00% | 123.282 NS | 30. April 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 84.436 NS | 31. Mai 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 21.333 NS | 30. April 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 720 NS | 30. April 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 33.452 NS | 30. April 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 5.252 NS | 31. Mai 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 4.473.029 SH | 8. August 2026 | Täglich |