DFTX Definium Therapeutics, Inc. - Common Shares
NASDAQ · Auf SEC EDGAR ansehen ↗ Schließen Okt 5, 2026 10-K/10-Q Aug 6, 2026DFTX Aktien-Snapshot Kurs, Marktkapitalisierung, P/E, EPS, ROE, Schulden/Eigenkapital, 52-Wochen-Spanne
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| Ex-Datum | Split | Typ |
|---|---|---|
| 29. August 2022 | 1-for-15 | Umgekehrt |
Über Definium Therapeutics, Inc. - Common Shares Unternehmensübersicht von Wikipedia
Definium Therapeutics, Inc., formerly known as MindMed, is a New York-based biotechnology company that is currently developing clinical and therapeutic applications for psychedelic and, more broadly, psychoplastogenic drugs.
History
MindMed was founded in May 2019 by Stephen Hurst and Jamon Rahn.
MindMed initially focused on developing treatments for opioid withdrawal and opioid use disorder with 18-MC, a non-hallucinogenic molecule based on the psychoactive alkaloid ibogaine. In June 2019, it acquired the 18-MC drug development program, previously funded by the National Institute on Drug Abuse, and in September began to prepare 18-MC for a Phase I FDA clinical trial to enable further clinical trials targeting opioid withdrawal and opioid use disorder.
MindMed was the first psychedelic pharmaceutical company to go public, listing on the Canadian NEO Exchange in March of 2020 through a reverse takeover with the Canadian gold mining company Broadway Gold Mining. It began trading on the Nasdaq as MNMD in April 2021 after being approved for an uplisting from the OTC Markets.
In a press release on June 9, 2021 MindMed announced that Jamon Rahn was stepping down both as the CEO and as a director on the board, to be replaced by then CDO Robert Barrow.
On February 26, 2021, MindMed closed its acquisition of digital health startup HealthMode. In connection with the acquisition, Daniel Karlin MD, CEO of HealthMode, was appointed to the position of CMO of the company.
On August 25, 2022, the first patient was dosed in a phase 2b trial for treatment of MM120 (now DT120) in generalized anxiety disorder (GAD). The study would go on to recruit 198 participants. The majority of trial participants experienced statistically significant improvements in their GAD scores, leading to the approval of multiple phase three human trials.
On January 12, 2026, MindMed rebranded to Definium Therapeutics.
Research
In March 2020, MindMed announced that it had partnered with NYU Langone to launch a clinical training program to train psychiatrists in psychedelic therapies and research to advance and deploy psychedelic medicines. The company committed $5 million to establish the center, which will also explore 18-MC and the use of drugs, including psilocybin-assisted therapy for alcohol use disorder.
In April 2020, the company entered into a long-term partnership with University Hospital Basel's Liechti Lab, gaining rights to more than ten years of the lab's data related to LSD, MDMA, and other psychedelic substances. The development of a novel compound designed to shorten the duration or stop an LSD experience that would allow LSD to be more widely used in a therapeutic environment was subsequently announced. Later that year a clinical trial studying the effects of DMT, the primary psychoactive ingredient in ayahuasca, and clinical trials combining MDMA and LSD were announced. A study to better understand and compare the altered states of consciousness induced by psilocybin and LSD began in August 2020,
and in October a Phase 1 study at the Liechti Lab on the acute dose dependent effects of LSD was completed. The results of the study were published by the American College of Neuropsychopharmacology in the journal Neuropsychopharmacology. In September 2021, further results were presented by Matthias Liechti, head of the Liechti Lab, at the INSIGHT Conference in Berlin. The results included the first clinical evidence on the comparative effects of LSD and psilocybin, stating 100mcg of LSD produced the same acute perceptual effects as a dose of 20 mg of psilocybin in healthy volunteers. Additionally, psilocybin taken after administering antidepressants for two weeks prior, was deemed safe, as well as reduced anxiety and blood pressure without hindering the psychedelic experience.
In December 2020, MindMed entered into an investigator-sponsored study agreement with Maastricht University in the Netherlands. The university provided facilities and personnel for a Phase 1 study to evaluate the effects of two low doses of LSD on mood, sleep and neuroplasticity.
In March 2024, the FDA granted breakthrough therapy designation to MindMed's form of LSD (MM120; now DT120) for the treatment of generalized anxiety disorder. This decision was influenced by a drug trial in which approximately half of the participants experienced significant relief from their symptoms. Positive results in clinical trials against general depression symptoms and generalized anxiety disorder were reported in 2026.
=== Ongoing clinical trials ===
Quelle: Wikipedia (Englisch), CC BY-SA 4.0 · Auf Wikipedia ansehen ↗
10-Jahres-Performance Umsatz-, Nettoergebnis-, Margen- und EPS-Trends
Bewertung P/E-, P/S-, P/B-, EV/EBITDA-Verhältnisse — ist die Aktie teuer oder günstig?
| Kennzahl | 5-Jahres-Trend | DFTX | 5-Jahres-Durchschnitt | Peer-Median | Fazit |
|---|---|---|---|---|---|
| P/E | -18.1 | · | · | · | |
| P/S | 894.0 | · | · | · | |
| K/B (MRQ) | 5.5 | · | · | · | |
| EV / EBITDA | -19.9 | · | · | · | |
| Price / Cash Flow (Kurs / Cashflow) | -28.0 | · | · | · | |
| EV / Revenue (EV / Umsatz) | 803.9 | · | · | · | |
| Price / Tangible Book (Kurs / Materieller Buchwert) | 11.8 | · | · | · |
Der Median der Vergleichsgruppe wird pro Kennzahl standardisiert berechnet und stimmt möglicherweise nicht immer mit der für diese Aktie angezeigten TTM/MRQ-Basis überein.
Rentabilität Brutto-, Betriebs- und Nettomargen; ROE, ROA, ROIC
| Kennzahl | 5-Jahres-Trend | DFTX | 5-Jahres-Durchschnitt | Peer-Median | Fazit |
|---|---|---|---|---|---|
| ROA | -49.5%5-Jahres-Durchschnitt ≈-55.1% | ≈-55.1% | · | · | |
| ROE | -71.0%5-Jahres-Durchschnitt ≈-64.1% | ≈-64.1% | · | · | |
| ROIC | -44.6% | · | · | · |
Finanzielle Gesundheit Verschuldung, Liquidität, Solvenz — Bilanzstärke
| Kennzahl | 5-Jahres-Trend | DFTX | 5-Jahres-Durchschnitt | Peer-Median | Fazit |
|---|---|---|---|---|---|
| Fremdkapital / Eigenkapital (MRQ) | 0.05-Jahres-Durchschnitt ≈0.1 | ≈0.1 | · | · | |
| Liquiditätsgrad (MRQ) | 6.95-Jahres-Durchschnitt ≈7.6 | ≈7.6 | · | · | |
| Quick Ratio | 6.25-Jahres-Durchschnitt ≈7.4 | ≈7.4 | · | · | |
| Langfristige Schulden / Eigenkapital (MRQ) | 0.05-Jahres-Durchschnitt ≈0.1 | ≈0.1 | · | · | |
| Interest Coverage (Zinsdeckungsgrad) | -30.3 | · | · | · |
Wachstum Umsatz-, EPS- und Nettoergebniswachstum: YoY, 3-Jahres-CAGR, 5-Jahres-CAGR
| Kennzahl | 5-Jahres-Trend | DFTX | 5-Jahres-Durchschnitt | Peer-Median | Fazit |
|---|---|---|---|---|---|
| Revenue YoY (Umsatz YoY) | 212.0% | · | · | · |
Kapitaleffizienz Umsatz pro Vermögenswert, Lagerumschlag, Forderungsumschlag
Noch nicht genügend Fundamentaldaten vorhanden, um diese Kennzahlengruppe zu berechnen.
Wert · ≈ 5-Jahres-Durchschnitt · Branchenmedian · Urteil relativ zum Median
Ergebnisverlauf EPS Ist vs. Schätzung, Überraschung %, Beat-Rate, nächstes Ergebnisdatum
| Zeitraum | Bericht | EPS Actual | EPS est. | Überraschung |
|---|---|---|---|---|
| 30. Juni 2026 | Aug 6, 2026 | $-1.44 | $-0.56 | -158.2% |
| 31. März 2026 | Mai 7, 2026 | $-0.71 | $-0.50 | -41.4% |
| 31. Dezember 2025 | $-0.50 | $-0.50 | -0.52% | |
| 30. September 2025 | $-0.78 | $-0.51 | -52.6% | |
| 30. Juni 2025 | $-0.50 | $-0.37 | -34.5% | |
| 31. März 2025 | $-0.27 | $-0.37 | 27.6% |
Vollständige Fundamentaldaten Alle Kennzahlen nach Jahr — Gewinn- und Verlustrechnung, Bilanz, Cashflow
Gewinn- und Verlustrechnung
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $118M | $65M | $52M | $36M | $35M | $19M | |
| SG&A Expense | $49M | $39M | $42M | $30M | $59M | $14M | |
| Operating Expenses | $166M | $104M | $94M | $66M | $94M | $33M | |
| Operating Income | $-166M | $-104M | $-94M | $-66M | $-94M | $-33M | |
| Interest Expense | $5M | $2M | $920.0K | · | · | · | |
| Other Non-op | $-17M | $-5M | $-2M | $10M | $-339.0K | $-907.0K | |
| Pretax Income | $-184M | $-109M | $-96M | $-57M | $-94M | $-34M | |
| Income Tax | $0 | · | · | · | $-1M | · | |
| Net Income | $-184M | $-109M | $-96M | $-57M | $-93M | $-34M | |
| EPS (Basic) | $-2.06 | $-1.54 | $-2.44 | $-1.84 | $-3.40 | · | |
| EPS (Diluted) | $-2.06 | $-1.54 | $-2.44 | $-1.84 | $-3.40 | · | |
| Shares (Basic) | 89,327,608 | 70,461,067 | 39,157,420 | 30,857,463 | 27,377,082 | · | |
| Shares (Diluted) | 89,327,608 | 70,461,067 | 39,157,420 | 30,857,463 | 27,377,082 | · | |
| EBITDA | $-166M | $-104M | $-94M | $-66M | $-94M | · |
Bilanz
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $258M | $274M | $100M | $142M | $134M | $80M | |
| Short-term Investments | $154M | $0 | · | · | · | · | |
| Prepaid Expense | $8M | $8M | $4M | $4M | $4M | $1M | |
| Current Assets | $419M | $282M | $104M | $146M | $137M | $82M | |
| Goodwill | $20M | $20M | $20M | $20M | $20M | $0 | |
| Intangibles | · | $0 | $527.0K | $4M | $7M | · | |
| Other Non-current Assets | $862.0K | $613.0K | $224.0K | $331.0K | · | · | |
| Total Assets | $440M | $302M | $125M | $170M | $164M | $82M | |
| Accounts Payable | $5M | $2M | $4M | $2M | $4M | $2M | |
| Accrued Liabilities | $20M | $13M | $12M | $6M | $6M | $986.0K | |
| Current Liabilities | $67M | $39M | $32M | $18M | $10M | $3M | |
| Other Non-current Liabilities | $496.0K | · | $32.0K | $1M | $2M | · | |
| Total Liabilities | $108M | $61M | $46M | $19M | $12M | $6M | |
| Total Debt | $41M | $22M | $14M | · | · | · | |
| Common Stock | · | · | $0 | · | · | · | |
| Retained Earnings | $-583M | $-399M | $-290M | $-194M | $-138M | $-45M | |
| AOCI | $1M | $819.0K | $343.0K | $627.0K | $1M | $284.0K | |
| Stockholders' Equity | $332M | $241M | $78M | $151M | $152M | $76M | |
| Liabilities + Equity | $440M | $302M | $125M | $170M | $164M | $82M | |
| Shares Outstanding | 98,776,265 | 75,100,763 | 41,101,303 | 37,979,136 | 28,126,414 | · |
Cashflow
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Deferred Tax | · | · | · | · | $-1M | · | |
| Amort. of Intangibles | $0 | $527.0K | $3M | $3M | $3M | $0 | |
| Operating Cash Flow | $-132M | $-79M | $-64M | $-50M | $-46M | $-24M | |
| Investing Cash Flow | $-152M | $0 | · | · | $-297.0K | · | |
| Stock Issued | $0 | $984.0K | $8M | $42M | $82M | $72M | |
| Net Stock Activity | $0 | $984.0K | $8M | $42M | $82M | · | |
| Financing Cash Flow | $267M | $253M | $22M | $59M | $99M | $97M | |
| Net Change in Cash | $-16M | $174M | $-42M | $9M | $53M | $73M | |
| Taxes Paid | $0 | · | · | · | · | · |
Rentabilität
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | -2012.6% | -4436.9% | 26143.2% | · | |
| Net Margin | · | · | -2052.6% | -3799.1% | 25915.3% | · | |
| Pretax Margin | · | · | -2052.6% | -3799.1% | 26237.6% | · | |
| EBITDA Margin | · | · | -2012.6% | -4436.9% | 26143.2% | · | |
| ROA | -49.5% | -50.9% | -65.0% | -34.0% | -75.8% | · | |
| ROE | -71.0% | -43.2% | -110.0% | -37.3% | -58.9% | · | |
| ROIC | -44.6% | · | · | · | -61.1% | · |
Liquidität & Solvenz
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 6.3 | 7.2 | 3.2 | 8.2 | 13.2 | · | |
| Quick Ratio | 6.2 | 7.0 | 3.1 | 7.9 | 12.8 | · | |
| Debt / Equity | 0.1 | 0.1 | 0.2 | · | · | · | |
| LT Debt / Equity | 0.1 | 0.1 | 0.2 | · | · | · | |
| Interest Coverage | -30.3 | -45.5 | · | · | · | · |
Effizienz
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | 0.0 | 0.0 | -0.0 | · |
Pro Aktie
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Book Value / Share | $3.36 | $3.21 | $1.90 | $3.97 | · | · | |
| Revenue / Share | · | · | $0.12 | $0.05 | · | · | |
| Cash Flow / Share | $-1.47 | $-1.12 | $-1.64 | $-1.62 | · | · | |
| Cash / Share | $2.61 | $3.65 | $2.43 | $3.74 | · | · | |
| EPS (TTM) | $-2.06 | $-1.54 | $-2.44 | $-1.84 | $-3.40 | · |
Wachstumsraten
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue YoY | · | · | 212.0% | · | · | · |
Bewertung (TTM)
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue TTM | $4M | $4M | $5M | $1M | $-359.0K | · | |
| Net Income TTM | $-184M | $-109M | $-96M | $-57M | $-93M | · | |
| Market Cap | $1.32B | $523M | · | · | · | · | |
| Enterprise Value | $952M | $271M | · | · | · | · | |
| P/E | -6.5 | -4.5 | · | · | · | · | |
| P/S | 321.2 | 126.9 | · | · | · | · | |
| P/B | 4.0 | 2.2 | · | · | · | · | |
| P / Tangible Book | 4.2 | 2.4 | · | · | · | · | |
| P / Cash Flow | -10.1 | -6.6 | · | · | · | · | |
| EV / EBITDA | -5.7 | -2.6 | · | · | · | · | |
| EV / Revenue | 231.1 | 65.8 | · | · | · | · | |
| Earnings Yield | -15.4% | -22.1% | · | · | · | · |
Gewinn- und Verlustrechnung
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $49M | $41M | $34M | $31M | $30M | $23M | $22M | $17M | $15M | $12M | $12M | $13M | $15M | $13M | $9M | $8M | |
| SG&A Expense | $26M | $18M | $14M | $15M | $11M | $9M | $11M | $8M | $10M | $10M | $11M | $8M | $14M | $8M | $5M | $9M | |
| Operating Expenses | $75M | $59M | $48M | $46M | $41M | $32M | $32M | $25M | $24M | $22M | $22M | $22M | $29M | $21M | $14M | $17M | |
| Operating Income | $-75M | $-59M | $-48M | $-46M | $-41M | $-32M | $-32M | $-25M | $-24M | $-22M | $-22M | $-22M | $-29M | $-21M | $-14M | $-17M | |
| Interest Expense | $1M | $1M | $1M | $1M | $2M | $602.0K | $656.0K | $727.0K | $466.0K | $434.0K | $439.0K | $328.0K | $77.0K | $76.0K | · | · | |
| Other Non-op | $-84M | $-18M | $-3M | $-22M | $-2M | $9M | $-2M | $11M | $19M | $-32M | $-2M | $4M | $54.0K | $-4M | $9M | $498.0K | |
| Pretax Income | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $-5M | $-16M | |
| Income Tax | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | |
| Net Income | $-159M | $-77M | $-50M | $-67M | $-43M | $-23M | $-35M | $-14M | $-6M | $-54M | $-24M | $-18M | $-29M | $-25M | $-5M | $-16M | |
| EPS (Basic) | $-1.44 | $-0.71 | $-0.51 | $-0.78 | $-0.50 | $-0.27 | $-0.14 | $-0.18 | $-0.08 | $-1.14 | $-0.58 | $-0.45 | $-0.76 | $-0.65 | $-0.02 | $-0.56 | |
| EPS (Diluted) | $-1.44 | $-0.71 | $-0.43 | $-0.78 | $-0.50 | $-0.35 | $0.13 | $-0.27 | $-0.26 | $-1.14 | $-0.58 | $-0.45 | $-0.76 | $-0.65 | $-0.02 | $-0.56 | |
| Shares (Basic) | 110,684,720 | 108,790,941 | · | 85,885,516 | 85,347,677 | 85,067,855 | · | 77,909,441 | 71,912,323 | 47,860,757 | · | 39,720,007 | 38,576,394 | 38,077,251 | · | 29,296,333 | |
| Shares (Diluted) | 110,684,720 | 108,790,941 | · | 85,885,516 | 85,347,677 | 87,091,461 | · | 80,238,688 | 75,304,101 | 47,860,757 | · | 39,720,007 | 38,576,394 | 38,077,251 | · | 29,296,333 | |
| EBITDA | $-75M | $-59M | · | $-46M | $-41M | $-32M | · | $-25M | $-24M | $-22M | · | $-22M | $-29M | $-21M | · | $-17M |
Bilanz
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $655M | $263M | $258M | $20M | $33M | $83M | $274M | $295M | $243M | $252M | $100M | $118M | $117M | $129M | $142M | $155M | |
| Short-term Investments | $429M | $111M | $154M | $189M | $150M | $130M | $0 | · | · | · | · | · | · | · | · | · | |
| Prepaid Expense | $8M | $7M | $8M | $7M | $6M | $9M | $8M | $4M | $5M | $3M | $4M | $2M | $3M | $3M | $4M | $2M | |
| Current Assets | $1.09B | $381M | $419M | $216M | $189M | $222M | $282M | $299M | $248M | $255M | $104M | $120M | $120M | $132M | $146M | $157M | |
| Goodwill | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | |
| Intangibles | · | · | · | · | · | · | · | · | · | · | $527.0K | $1M | $2M | $3M | $4M | $4M | |
| Other Non-current Assets | $880.0K | $812.0K | $862.0K | $1M | $1M | $606.0K | $613.0K | $493.0K | $534.0K | $144.0K | $224.0K | $229.0K | $268.0K | $300.0K | $331.0K | · | |
| Total Assets | $1.11B | $401M | $440M | $237M | $265M | $275M | $302M | $320M | $268M | $276M | $125M | $142M | $142M | $156M | $170M | $181M | |
| Accounts Payable | $7M | $7M | $5M | $8M | $4M | $2M | $2M | $2M | $3M | $8M | $4M | $8M | $9M | $2M | $2M | $824.0K | |
| Accrued Liabilities | $37M | $25M | $20M | $19M | $15M | $11M | $13M | $9M | $8M | $10M | $12M | $10M | $10M | $7M | $6M | $7M | |
| Current Liabilities | $157M | $81M | $67M | $65M | $38M | $30M | $39M | $33M | $42M | $65M | $32M | $31M | $35M | $24M | $18M | $26M | |
| Other Non-current Liabilities | $549.0K | $559.0K | $496.0K | $519.0K | $543.0K | · | · | · | · | $15.0K | $32.0K | $349.0K | $992.0K | $1M | $1M | $1M | |
| Total Liabilities | $194M | $122M | $108M | $106M | $80M | $53M | $61M | $58M | $66M | $79M | $46M | $46M | $36M | $25M | $19M | $27M | |
| Total Debt | $36M | $41M | · | $40M | $41M | $22M | · | $24M | $24M | $14M | · | $14M | · | · | · | · | |
| Common Stock | · | · | · | · | · | · | · | $0 | $0 | · | $0 | · | · | · | · | · | |
| Retained Earnings | $-819M | $-660M | $-583M | $-532M | $-465M | $-422M | $-399M | $-364M | $-350M | $-345M | $-290M | $-266M | $-248M | $-219M | $-194M | $-190M | |
| AOCI | $417.0K | $824.0K | $1M | $1M | $807.0K | $802.0K | $819.0K | $821.0K | $833.0K | $836.0K | $343.0K | $777.0K | $362.0K | $641.0K | $627.0K | $743.0K | |
| Stockholders' Equity | $919M | $279M | $332M | $131M | $185M | $223M | $241M | $262M | $202M | $196M | $78M | $96M | $106M | $130M | $151M | $154M | |
| Liabilities + Equity | $1.11B | $401M | $440M | $237M | $265M | $275M | $302M | $320M | $268M | $276M | $125M | $142M | $142M | $156M | $170M | $181M | |
| Shares Outstanding | 134,365,950 | 104,044,508 | 98,776,265 | 76,774,057 | 75,803,251 | 75,511,375 | 75,100,763 | 81,590,491 | 72,075,076 | 71,163,720 | 41,101,303 | 40,094,708 | 38,807,159 | 38,290,111 | 37,979,136 | 37,541,115 |
Cashflow
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Amort. of Intangibles | · | · | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $527.0K | $771.0K | $800.0K | $800.0K | $791.0K | $800.0K | $800.0K | |
| Operating Cash Flow | $-53M | $-43M | $-43M | $-30M | $-30M | $-29M | $-25M | $-17M | $-20M | $-17M | $-21M | $-17M | $-14M | $-13M | $-13M | $-9M | |
| Investing Cash Flow | $-317M | $42M | $35M | $15M | $-40M | $-162M | $0 | $0 | $0 | $0 | · | · | · | · | · | · | |
| Stock Issued | · | · | $0 | $0 | · | · | $0 | $0 | · | · | $3M | $3M | $1M | $583.0K | $730.0K | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | · | · | · | · | $583.0K | · | · | |
| Financing Cash Flow | $762M | $5M | $246M | $749.0K | $20M | $1M | $4M | $69M | $11M | $169M | $3M | $17M | $1M | $583.0K | $416.0K | $58M | |
| Net Change in Cash | $393M | $5M | $238M | $-13M | $-49M | $-191M | $-22M | $52M | $-9M | $153M | $-18M | $804.0K | $-13M | $-13M | $-12M | $49M |
Rentabilität
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | · | · | · | · | -1858.6% | -2226.1% | -1624.8% | · | -4717.5% | |
| Net Margin | · | · | · | · | · | · | · | · | · | · | · | -1541.1% | -2222.0% | -1932.6% | · | -4579.2% | |
| Pretax Margin | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | -4579.2% | |
| EBITDA Margin | · | · | · | · | · | · | · | · | · | · | · | -1858.6% | -2226.1% | -1624.8% | · | -4717.5% | |
| ROA | -23.1% | -22.8% | · | -24.2% | -16.0% | -8.5% | · | -5.9% | -2.9% | -25.2% | · | -11.1% | -21.1% | -16.3% | · | -18.2% | |
| ROE | -28.8% | -30.7% | · | -34.2% | -22.1% | -11.2% | · | -7.6% | -3.8% | -33.3% | · | -14.4% | -25.3% | -18.6% | · | -21.5% | |
| ROIC | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | -11.1% |
Liquidität & Solvenz
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 6.9 | 4.7 | · | 3.3 | 5.0 | 7.3 | · | 9.0 | 5.9 | 3.9 | · | 3.9 | 3.4 | 5.5 | · | 6.0 | |
| Quick Ratio | 6.9 | 4.6 | · | 3.2 | 4.8 | 7.0 | · | 8.9 | 5.8 | 3.9 | · | 3.8 | 3.3 | 5.4 | · | 5.9 | |
| Debt / Equity | 0.0 | 0.1 | · | 0.3 | 0.2 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 | · | · | · | · | |
| LT Debt / Equity | 0.0 | 0.1 | · | 0.3 | 0.2 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 | · | · | · | · | |
| Interest Coverage | -60.9 | -47.6 | · | -35.8 | -17.5 | -53.4 | · | -34.1 | -52.5 | -51.2 | · | · | · | · | · | · |
Effizienz
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | · | · | · | · | · | · | 0.0 | 0.0 | 0.0 | · | 0.0 |
Pro Aktie
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $6.84 | $2.68 | · | $1.70 | $2.45 | $2.95 | · | $3.21 | $2.80 | $2.75 | · | $2.39 | $2.73 | $3.40 | · | $4.09 | |
| Revenue / Share | · | · | · | · | · | · | · | · | · | · | · | $0.03 | $0.03 | $0.03 | · | $0.01 | |
| Cash Flow / Share | · | $-0.39 | · | · | · | $-0.34 | · | · | · | $-0.35 | · | · | · | $-0.35 | · | · | |
| Cash / Share | $4.88 | $2.52 | · | $0.26 | $0.44 | $1.10 | · | $3.62 | $3.37 | $3.55 | · | $2.94 | $3.01 | $3.38 | · | $4.12 | |
| EPS (TTM) | $-3.36 | $-2.42 | · | $-1.50 | $-0.99 | $-0.75 | · | $-2.25 | $-2.43 | $-2.93 | · | $-1.88 | $-1.99 | $-1.83 | · | $-2.41 |
Bewertung (TTM)
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $5M | $5M | · | $5M | $5M | $5M | · | $5M | $5M | $5M | · | $5M | $4M | $3M | · | $276.0K | |
| Net Income TTM | $-354M | $-238M | · | $-168M | $-115M | $-78M | · | $-98M | $-102M | $-125M | · | $-77M | $-75M | $-63M | · | $-69M | |
| Market Cap | $6.32B | $1.97B | · | $905M | $492M | $442M | · | $464M | $520M | $669M | · | · | · | · | · | · | |
| Enterprise Value | $5.27B | $1.63B | · | $736M | $350M | $251M | · | $193M | $301M | $431M | · | · | · | · | · | · | |
| P/E | -14.0 | -7.8 | · | -7.9 | -6.6 | -7.8 | · | -2.5 | -3.0 | -3.2 | · | · | · | · | · | · | |
| P/S | 1306.4 | 406.5 | · | 187.1 | 101.7 | 91.3 | · | 96.0 | 107.4 | 138.3 | · | · | · | · | · | · | |
| P/B | 6.9 | 7.1 | · | 6.9 | 2.7 | 2.0 | · | 1.8 | 2.6 | 3.4 | · | · | · | · | · | · | |
| P / Tangible Book | 7.0 | 7.6 | · | 8.2 | 3.0 | 2.2 | · | 1.9 | 2.9 | 3.8 | · | · | · | · | · | · | |
| P / Cash Flow | · | -46.1 | · | · | · | -15.0 | · | · | · | -40.3 | · | · | · | · | · | · | |
| EV / Revenue | 1089.9 | 337.7 | · | 152.2 | 72.4 | 52.0 | · | 39.9 | 62.2 | 89.0 | · | · | · | · | · | · | |
| Earnings Yield | -7.1% | -12.8% | · | -12.7% | -15.2% | -12.8% | · | -39.5% | -33.7% | -31.2% | · | · | · | · | · | · |
Aktuellster Zeitraum links · fehlende Werte werden als · angezeigt
Finanzberichte Gewinn- und Verlustrechnung, Bilanz, Cashflow — jährlich, letzte 5 Jahre
| Kennzahl | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Betriebsgewinnmarge % | · | · | -2012.6% | -4436.9% | 26143.2% |
| Nettoergebnis | $-184M | $-109M | $-96M | $-57M | $-93M |
| Verwässerte EPS | $-2.06 | $-1.54 | $-2.44 | $-1.84 | $-3.40 |
| Kennzahl | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Fremdkapital / Eigenkapital | 0.1 | 0.1 | 0.2 | · | · |
| Liquiditätsgrad | 6.3 | 7.2 | 3.2 | 8.2 | 13.2 |
| Quick Ratio | 6.2 | 7.0 | 3.1 | 7.9 | 12.8 |
Noch nicht genügend Fundamentaldaten vorhanden, um diese Aufstellung zu erstellen.
Institutionelle Eigentümer (13F) 389 Einreicher · $5.1B gesamt · Stand 30. September 2026
Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.
| Neue Positionen | Geschlossene Positionen | Erhöht | Abgenommen | Nettoveränderung der Aktien |
|---|---|---|---|---|
| 163 | 28 | 120 | 65 | · |
Verglichen mit Q1 2026. SEC-Formular 13F-Einreichungen sind innerhalb von 45 Tagen nach Quartalsende fällig, zuzüglich einer kurzen Pufferzeit für verspätete Einreicher — Quartale, die noch in diesem Fenster liegen, werden zugunsten des letzten vollständig berichteten Paares übersprungen. Änderung gegenüber Vorquartal nicht angezeigt: Die Einreicherabdeckung unterscheidet sich zwischen diesen beiden Quartalen zu stark für einen zuverlässigen Vergleich.
| Institution | Wert | Aktien | % der verfolgten 13F | Typ |
|---|---|---|---|---|
| BlackRock, Inc. | $528.392.511 | 11.232.834 | 10,30% | Aktien |
| Avoro Capital Advisors LLC | $338.165.292 | 7.188.888 | 6,59% | Aktien |
| Driehaus Capital Management LLC | $322.001.783 | 6.845.276 | 6,28% | Aktien |
| Capital World Investors | $252.497.690 | 5.367.723 | 4,92% | Aktien |
| FMR LLC | $223.577.402 | 4.752.921 | 4,36% | Aktien |
| GEODE CAPITAL MANAGEMENT, LLC | $171.482.802 | 3.644.813 | 3,34% | Aktien |
| STATE STREET CORP | $144.195.946 | 3.065.390 | 2,81% | Aktien |
| Capital International Investors | $139.398.806 | 2.963.410 | 2,72% | Aktien |
| Octagon Capital Advisors LP | $138.768.000 | 2.950.000 | 2,71% | Aktien |
| WELLINGTON MANAGEMENT GROUP LLP | $138.755.487 | 2.949.734 | 2,71% | Aktien |
| Deep Track Capital, LP | $129.360.000 | 2.750.000 | 2,52% | Aktien |
| Commodore Capital LP | $94.080.000 | 2.000.000 | 1,83% | Aktien |
| GOLDMAN SACHS GROUP INC | $84.712.079 | 1.800.852 | 1,65% | Aktien |
| CITADEL ADVISORS LLC | $79.431.133 | 1.688.587 | 1,55% | Aktien |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $77.541.959 | 1.648.426 | 1,51% | Aktien |
| RA CAPITAL MANAGEMENT, L.P. | $70.560.000 | 1.500.000 | 1,38% | Aktien |
| VANGUARD CAPITAL MANAGEMENT LLC | $69.922.796 | 1.486.454 | 1,36% | Aktien |
| JANUS HENDERSON GROUP PLC | $67.226.955 | 3.556.041 | 1,31% | Aktien |
| Siren, L.L.C. | $66.772.951 | 1.419.493 | 1,30% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $65.216.256 | 1.386.400 | 1,27% | Kaufoption |
| MARSHALL WACE, LLP | $61.102.420 | 1.298.946 | 1,19% | Aktien |
| NORTHERN TRUST CORP | $55.000.956 | 1.169.238 | 1,07% | Aktien |
| AMERIPRISE FINANCIAL INC | $54.018.997 | 1.148.363 | 1,05% | Aktien |
| Nuveen, LLC | $51.993.971 | 1.105.314 | 1,01% | Aktien |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $50.971.415 | 1.083.576 | 0,99% | Aktien |
| Woodline Partners LP | $47.211.273 | 1.003.641 | 0,92% | Aktien |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $47.040.000 | 1.000.000 | 0,92% | Aktien |
| Boxer Capital Management, LLC | $46.969.440 | 998.500 | 0,92% | Aktien |
| TWO SIGMA INVESTMENTS, LP | $43.362.319 | 921.818 | 0,85% | Aktien |
| Balyasny Asset Management L.P. | $42.217.365 | 897.478 | 0,82% | Aktien |
| VANGUARD FIDUCIARY TRUST CO | $38.934.679 | 827.693 | 0,76% | Aktien |
| Holocene Advisors, LP | $37.470.841 | 796.574 | 0,73% | Aktien |
| AWM Investment Company, Inc. | $36.916.992 | 784.800 | 0,72% | Aktien |
| Bank of New York Mellon Corp | $36.562.821 | 777.271 | 0,71% | Aktien |
| Polar Capital Holdings Plc | $36.561.981 | 777.253 | 0,71% | Aktien |
| ALLIANCEBERNSTEIN L.P. | $34.082.124 | 1.803.287 | 0,66% | Aktien |
| EVENTIDE ASSET MANAGEMENT, LLC | $33.398.400 | 710.000 | 0,65% | Aktien |
| NEUBERGER BERMAN GROUP LLC | $32.341.834 | 687.539 | 0,63% | Aktien |
| Qube Research & Technologies Ltd | $32.123.663 | 682.901 | 0,63% | Aktien |
| Candriam S.C.A. | $28.874.744 | 614.425 | 0,56% | Aktien |
| ArrowMark Colorado Holdings LLC | $26.533.806 | 564.069 | 0,52% | Aktien |
| Catalio Capital Management, LP | $26.468.091 | 562.672 | 0,52% | Aktien |
| Blackstone Inc. | $26.418.228 | 561.612 | 0,52% | Aktien |
| Integral Health Asset Management, LLC | $25.872.000 | 550.000 | 0,50% | Aktien |
| BAMCO INC /NY/ | $24.465.880 | 520.108 | 0,48% | Aktien |
| UBS Group AG | $23.494.928 | 499.467 | 0,46% | Aktien |
| FRANKLIN RESOURCES INC | $22.871.742 | 486.219 | 0,45% | Aktien |
| Point72 Asset Management, L.P. | $22.766.419 | 483.980 | 0,44% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $22.155.840 | 471.000 | 0,43% | Verkaufsoption |
| Ensign Peak Advisors, Inc | $21.925.626 | 466.106 | 0,43% | Aktien |
Unternehmensinsider 16 Insider · 9 Führungskräfte · 9 Direktoren
| Insider | Rolle | Letzte Aktivität | Gehaltene Aktien | Käufe 12m | Verkäufe 12m | Netto 12m |
|---|---|---|---|---|---|---|
| Robert Barrow | Chief Executive Officer | 25. September 2026 S | 2.213.090 | 0 | 5 | $-3.981.146 |
| Brandi Roberts | Chief Financial Officer | 25. September 2026 S | 394.528 | 0 | 2 | $-259.172 |
| Schond L. Greenway | Chief Financial Officer | 25. März 2024 F | 211.057 | 0 | 0 | $0 |
| Miri Halperin Wernli | Executive President | 21. August 2024 M | 202.405 | 0 | 0 | $0 |
| Dan Karlin | Chief Medical Officer | 25. September 2026 S | 792.846 | 0 | 4 | $-1.070.502 |
| Matthew T. Wiley | Chief Commercial Officer | 25. September 2026 S | 359.036 | 0 | 2 | $-242.358 |
| Mark Sullivan | Chief Legal Officer | 25. September 2026 S | 494.228 | 0 | 4 | $-1.445.540 |
| Carrie Liao | Chief Accounting Officer | 25. März 2025 S | 144.923 | 0 | 0 | $0 |
| Cynthia W. Hu | Chief Legal Officer&Secretary | 24. März 2022 A | 1.200.000 | 0 | 0 | $0 |
| Andreas Krebs | Direktor | 18. September 2026 M | 21.402 | 0 | 0 | $0 |
| Carol A Vallone | Direktor | 18. September 2026 M | 22.296 | 0 | 0 | $0 |
| Roger Adsett | Direktor | 11. Juni 2026 A | 3.555 | 0 | 0 | $0 |
| Roger Crystal | Direktor | 11. Juni 2026 A | 24.289 | 0 | 0 | $0 |
| Suzanne Louise Bruhn | Direktor | 11. Juni 2026 A | 24.289 | 0 | 0 | $0 |
| David W Gryska | Direktor | 11. Juni 2026 A | 19.900 | 0 | 0 | $0 |
| Brigid Makes | Direktor | 1. Juni 2022 A | 158.706 | 0 | 0 | $0 |
Insider aus SEC-Einreichungen Form 3/4/5; Netto = nur P/S aus offenen Märkten
ETF-Besitz Gehalten von 22 ETFs
Gewichtung spiegelt nur direkte Aktienbestände (N-PORT) wider; gehebelte oder derivatbasierte Fonds können zusätzliche Swap-Exposure halten, die hier nicht angezeigt wird.
| Fonds | Gewicht | Anteile | Stand | Quelle |
|---|---|---|---|---|
| PILL · Direxion Shares ETF Trust | 2,13% | 10.109 NS | 31. Juli 2026 | N-PORT |
| BBC · ETFis Series Trust I | 1,18% | 12.558 NS | 31. Juli 2026 | N-PORT |
| IHE · iShares Trust | 1,12% | 479.902 SH | 11. September 2026 | Täglich |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,36% | 139.235 SH | 19. August 2026 | Täglich |
| IBB · iShares Trust | 0,36% | 974.814 SH | 11. September 2026 | Täglich |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,34% | 9.504 SH | 2. Oktober 2026 | Täglich |
| IWO · iShares Trust | 0,32% | 1.221.670 SH | 11. September 2026 | Täglich |
| NUSC · Nushares ETF Trust | 0,31% | 90.473 NS | 31. Juli 2026 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0,20% | 86.461 SH | 19. August 2026 | Täglich |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,19% | 748.959 SH | 19. August 2026 | Täglich |
| RSSL · Global X Funds | 0,18% | 62.307 NS | 31. Juli 2026 | N-PORT |
| IWM · iShares Trust | 0,16% | 3.329.545 SH | 11. September 2026 | Täglich |
| ESML · iShares Trust | 0,10% | 73.991 SH | 11. September 2026 | Täglich |
| VHT · VANGUARD WORLD FUND | 0,08% | 331.180 SH | 19. August 2026 | Täglich |
| VXF · VANGUARD INDEX FUNDS | 0,07% | 1.486.454 SH | 19. August 2026 | Täglich |
| FHLC · FIDELITY COVINGTON TRUST | 0,07% | 52.257 NS | 31. Juli 2026 | N-PORT |
| FBCG · FIDELITY COVINGTON TRUST | 0,06% | 103.206 NS | 31. Juli 2026 | N-PORT |
| WSML · iShares Trust | 0,04% | 6.834 SH | 11. September 2026 | Täglich |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,03% | 17.940 SH | 2. Oktober 2026 | Täglich |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,01% | 10.703 SH | 19. August 2026 | Täglich |
| IWV · iShares Trust | 0,01% | 34.866 SH | 10. September 2026 | Täglich |
| ITOT · iShares Trust | 0,01% | 161.931 SH | 11. September 2026 | Täglich |
DFTX Analysten-Konsens Bullische und bärische Analystenmeinungen, 12-Monats-Kursziel, Aufwärtspotenzial
12-Monats-Kursziel
17 Analysten · 2026-10-04Mittelwert-Ziel $71.65 +92,2%
Peer-Vergleich (GICS-Subbranche) Wichtige Kennzahlen im Vergleich zu Branchenkollegen
FY-Basis, Kurse zum Schlusskurs am Ende des letzten Geschäftsjahres jedes Unternehmens.
| Ticker | Marktkapitalisierung | P/E | Umsatz Vj. | Nettomarge | ROE | Bruttogewinnmarge |
|---|---|---|---|---|---|---|
| DFTX | $1.32B | -6.5 | 212.0% | · | -71.0% | · |
| AMRX | · | 57.3 | 8.1% | 2.4% | -80.0% | 36.9% |
| BLTE | $6.29B | -69.2 | · | · | -16.9% | · |
| LGND | $3.74B | 30.8 | 60.4% | 46.4% | 13.5% | · |
| MANE | · | · | · | · | 82.6% | · |
| EWTX | $2.64B | -15.2 | · | · | -30.2% | · |
| INDV | · | 21.9 | 4.3% | 17.0% | -118.3% | 80.2% |
| OGN | $1.87B | 10.0 | -2.9% | 3.0% | 25.2% | 53.3% |
| TARS | $3.48B | -51.5 | 146.7% | -14.7% | -19.7% | · |
| AMLX | $1.33B | -7.9 | -77.1% | · | -61.2% | · |
Meine Kennzahlen Ihre persönliche Watchlist — ausgewählte Zeilen aus den vollständigen Fundamentaldaten
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