EWTX Edgewise Therapeutics, Inc. - Common Stock
$46,22
Kurs · Aug 19, 2026
Fundamentaldaten per Aug 6, 2026
52W-Spanne
$14–$48
94% of range
Analystenbewertung
BUY
19 analysts
Kursziel
$51
+11% upside
P/E (TTM)
-28.7
ROE
-30.2%
Nettogewinnmarge
—
EWTX Aktien-Snapshot Kurs, Marktkapitalisierung, P/E, EPS, ROE, Schulden/Eigenkapital, 52-Wochen-Spanne
Kurs
$46.22
Marktkapitalisierung
$4.97B
P/E (TTM)
-28.7
EPS (TTM)
$-1.63
Umsatz (TTM)
—
Dividendenrendite
—
ROE
-30.2%
Verschuldungsgrad
—
52W-Spanne
$14 – $48
EWTX Aktienkurs-Chart Täglich OHLCV mit technischen Indikatoren — Schwenken, Zoom und Ansicht anpassen
Configure
10-Jahres-Performance Umsatz-, Nettoergebnis-, Margen- und EPS-Trends
Umsatz & Nettoergebnis
—
EPS
$-1.63
2020-12-31
→
2025-12-31
Freier Cashflow
$-144M
2021-12-31
→
2025-12-31
Margen
—
Bewertung P/E-, P/S-, P/B-, EV/EBITDA-Verhältnisse — ist die Aktie teuer oder günstig?
Kennzahl
5-Jahres-Trend
EWTX
Peer-Median
P/E (TTM)
-28.7
38.7
P/B (K/B)
9.5
3.8
Price / FCF (Kurs / FCF)
-34.5
—
Rentabilität Brutto-, Betriebs- und Nettomargen; ROE, ROA, ROIC
Kennzahl
5-Jahres-Trend
EWTX
Peer-Median
ROA
-32.3%
-6.4%
ROE
-30.2%
-16.8%
ROIC
-36.6%
—
Finanzielle Gesundheit Verschuldung, Liquidität, Solvenz — Bilanzstärke
Kennzahl
5-Jahres-Trend
EWTX
Peer-Median
Current Ratio (Liquiditätsgrad)
19.9
12.8
Quick Ratio
2.2
—
Wachstum Umsatz-, EPS- und Nettoergebniswachstum: YoY, 3-Jahres-CAGR, 5-Jahres-CAGR
Kennzahl
5-Jahres-Trend
EWTX
Peer-Median
Kapitaleffizienz Umsatz pro Vermögenswert, Lagerumschlag, Forderungsumschlag
Kennzahl
5-Jahres-Trend
EWTX
Peer-Median
EWTX Analysten-Konsens Bullische und bärische Analystenmeinungen, 12-Monats-Kursziel, Aufwärtspotenzial
KAUF
19 Analysten
- Starker Kauf 7 36,8%
- Kauf 9 47,4%
- Halten 3 15,8%
- Verkauf 0 0,0%
- Starker Verkauf 0 0,0%
12-Monats-Kursziel
13 Analysten · 2026-08-18
Median
$52.00
Jetzt
$46.22
Tief
$36.00
Hoch
$66.00
Median-Ziel
$52.00
+12,5%
Mittelwert-Ziel
$51.15
+10,7%
Ergebnisverlauf EPS Ist vs. Schätzung, Überraschung %, Beat-Rate, nächstes Ergebnisdatum
Durchschn. Überraschung
0.01%
| Zeitraum | EPS Actual | EPS est. | Überraschung |
|---|---|---|---|
| 30. Juni 2026 | $-0.53 | $-0.48 | -0.05% |
| 31. März 2026 | $-0.46 | $-0.50 | 0.04% |
| 31. Dezember 2025 | $-0.47 | $-0.44 | -0.03% |
| 30. September 2025 | $-0.39 | $-0.41 | 0.02% |
| 30. Juni 2025 | $-0.34 | $-0.42 | 0.08% |
| 31. März 2025 | $-0.43 | $-0.44 | 0.01% |
Peer-Vergleich (GICS-Subbranche) Wichtige Kennzahlen im Vergleich zu Branchenkollegen
| Ticker | Marktkapitalisierung | P/E | Umsatz Vj. | Nettomarge | ROE | Bruttogewinnmarge |
|---|---|---|---|---|---|---|
| EWTX | $2.64B | -15.2 | — | — | -30.2% | — |
| BLTE | — | — | — | — | — | — |
| DFTX | $1.32B | -6.5 | 212.0% | — | -71.0% | — |
| AMRX | — | 57.3 | 8.1% | 2.4% | -80.0% | 36.9% |
| LGND | $3.74B | 30.8 | 60.4% | 46.4% | 13.5% | — |
| MANE | — | — | — | — | 82.6% | — |
| INDV | — | 21.9 | 4.3% | 17.0% | -118.3% | 80.2% |
| ELVN | $915M | -8.4 | — | — | -21.9% | — |
| AMLX | $1.33B | -7.9 | -77.1% | — | -61.2% | — |
| GPCR | $14.78B | -86.9 | — | — | -12.3% | — |
| OGN | $1.87B | 10.0 | -2.9% | 3.0% | 25.2% | 53.3% |
Vollständige Fundamentaldaten Alle Kennzahlen nach Jahr — Gewinn- und Verlustrechnung, Bilanz, Cashflow
Gewinn- und Verlustrechnung 12
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $151M | $127M | $91M | $54M | $32M | $15M | |
| SG&A Expense | $40M | $32M | $23M | $18M | $11M | $2M | |
| Operating Expenses | $191M | $159M | $114M | $72M | $43M | $17M | |
| Operating Income | $-191M | $-159M | $-114M | $-72M | $-43M | $-17M | |
| Pretax Income | $-168M | $-134M | $-100M | · | · | · | |
| Income Tax | $4.0K | $3.0K | $4.0K | $0 | $0 | · | |
| Net Income | $-168M | $-134M | $-100M | $-68M | $-43M | $-17M | |
| EPS (Basic) | $-1.63 | $-1.45 | $-1.57 | $-1.26 | $-1.14 | $-23.17 | |
| EPS (Diluted) | $-1.63 | $-1.45 | $-1.57 | $-1.26 | $-1.14 | $-23.17 | |
| Shares (Basic) | 102,930,744 | 92,414,626 | 63,723,600 | 53,593,753 | 37,526,332 | 739,004 | |
| Shares (Diluted) | 102,930,744 | 92,414,626 | 63,723,600 | 53,593,753 | 37,526,332 | 739,004 | |
| EBITDA | $-191M | $-159M | $-114M | $-72M | $-43M | · |
Bilanz 21
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $61M | $42M | $86M | $22M | $16M | $105M | |
| Prepaid Expense | $13M | $5M | $9M | $5M | $3M | $551.0K | |
| Current Assets | $543M | $475M | $327M | $357M | $284M | $130M | |
| PP&E (Net) | $8M | $10M | $10M | $9M | $912.0K | $516.0K | |
| PP&E (Gross) | $15M | $14M | $13M | $10M | $2M | $946.0K | |
| Accum. Depreciation | $7M | $5M | $3M | $1M | $702.0K | $430.0K | |
| Other Non-current Assets | · | $262.0K | $348.0K | $251.0K | $548.0K | $975.0K | |
| Total Assets | $553M | $487M | $340M | $367M | $285M | $131M | |
| Accounts Payable | $6M | $6M | $4M | $6M | $4M | $2M | |
| Accrued Liabilities | $8M | $7M | $6M | $6M | $4M | $2M | |
| Current Liabilities | $27M | $24M | $17M | $17M | $11M | $4M | |
| Capital Leases | $3M | $4M | $4M | $4M | · | · | |
| Other Non-current Liabilities | · | · | · | · | $329.0K | · | |
| Total Liabilities | $30M | $28M | $21M | $20M | $11M | $4M | |
| Common Stock | $10.0K | $9.0K | $7.0K | $6.0K | $5.0K | · | |
| Paid-in Capital | $1.07B | $837M | $563M | $493M | $352M | $727.0K | |
| Retained Earnings | $-546M | $-379M | $-245M | $-145M | $-77M | $-34M | |
| AOCI | $677.0K | $420.0K | $99.0K | $-1M | $-514.0K | · | |
| Stockholders' Equity | $522M | $459M | $319M | $347M | $274M | $-33M | |
| Liabilities + Equity | $553M | $487M | $340M | $367M | $285M | $131M | |
| Shares Outstanding | 106,249,579 | 94,838,466 | 70,453,342 | 63,257,376 | 49,500,308 | 1,009,479 |
Cashflow 9
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Stock-based Comp | $35M | $25M | $18M | $11M | $4M | $354.0K | |
| Operating Cash Flow | $-144M | $-109M | $-92M | $-53M | $-34M | $-15M | |
| CapEx | $256.0K | $1M | $6M | $6M | $668.0K | $203.0K | |
| Investing Cash Flow | $-33M | $-185M | $103M | $-71M | $-242M | $-24M | |
| Stock Issued | $187M | $239M | $53M | $129M | · | · | |
| Net Stock Activity | $187M | $239M | $53M | $129M | · | · | |
| Financing Cash Flow | $196M | $249M | $53M | $130M | $186M | $120M | |
| Net Change in Cash | $19M | $-44M | $64M | $6M | $-89M | $81M | |
| Free Cash Flow | $-144M | $-110M | $-98M | $-58M | $-34M | · |
Rentabilität 3
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -32.3% | -32.4% | -28.3% | -20.7% | -20.6% | · | |
| ROE | -30.2% | -28.2% | -32.9% | -19.1% | -15.3% | · | |
| ROIC | -36.6% | · | · | · | · | · |
Liquidität & Solvenz 2
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 19.9 | 19.9 | 19.5 | 21.5 | 27.0 | · | |
| Quick Ratio | 2.2 | 1.7 | 5.1 | 1.3 | 1.5 | · |
Bewertung (TTM) 8
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-168M | $-134M | $-100M | $-68M | $-43M | · | |
| Market Cap | $2.64B | $2.53B | $771M | $566M | $756M | · | |
| P/E | -15.2 | -18.4 | -7.0 | -7.1 | -13.4 | · | |
| P/B | 5.0 | 5.5 | 2.4 | 1.6 | 2.8 | · | |
| P / Tangible Book | 5.0 | 5.5 | 2.4 | 1.6 | 2.8 | · | |
| P / Cash Flow | -18.3 | -23.2 | -8.4 | -10.7 | -22.6 | · | |
| P / FCF | -18.3 | -22.9 | -7.9 | -9.7 | -22.1 | · | |
| Earnings Yield | -6.6% | -5.4% | -14.3% | -14.1% | -7.5% | · |
Gewinn- und Verlustrechnung 10
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $48M | $43M | $44M | $37M | $34M | $37M | $36M | $32M | $31M | $28M | $24M | $20M | $20M | $17M | $14M | $12M | |
| SG&A Expense | $14M | $11M | $12M | $9M | $9M | $9M | $9M | $8M | $7M | $7M | $6M | $6M | $6M | $5M | $4M | $4M | |
| Operating Expenses | $62M | $54M | $56M | $47M | $43M | $46M | $46M | $40M | $38M | $35M | $29M | $25M | $26M | $22M | $18M | $16M | |
| Operating Income | $-62M | $-54M | $-56M | $-47M | $-43M | $-46M | $-46M | $-40M | $-38M | $-35M | $-29M | $-25M | $-26M | $-22M | $-18M | $-16M | |
| Net Income | $-57M | $-49M | $-50M | $-41M | $-36M | $-41M | $-40M | $-34M | $-31M | $-29M | $-26M | $-21M | $-23M | $-19M | $-17M | $-16M | |
| EPS (Basic) | $-0.53 | $-0.46 | $-0.47 | $-0.39 | $-0.34 | $-0.43 | $-0.42 | $-0.36 | $-0.34 | $-0.33 | $-0.41 | $-0.34 | $-0.36 | $-0.30 | $-0.34 | $-0.32 | |
| EPS (Diluted) | $-0.53 | $-0.46 | $-0.47 | $-0.39 | $-0.34 | $-0.43 | $-0.42 | $-0.36 | $-0.34 | $-0.33 | $-0.41 | $-0.34 | $-0.36 | $-0.30 | $-0.34 | $-0.32 | |
| Shares (Basic) | 107,669,774 | 107,116,709 | -202,632,581 | 105,492,779 | 104,940,493 | 95,130,053 | -182,481,383 | 93,813,346 | 93,515,356 | 87,567,307 | 63,459,560 | 63,380,430 | 63,265,800 | -97,418,492 | 51,844,904 | 49,622,752 | |
| Shares (Diluted) | 107,669,774 | 107,116,709 | -202,632,581 | 105,492,779 | 104,940,493 | 95,130,053 | -182,481,383 | 93,813,346 | 93,515,356 | 87,567,307 | 63,459,560 | 63,380,430 | 63,265,800 | -97,418,492 | 51,844,904 | 49,622,752 | |
| EBITDA | $-62M | $-54M | · | $-47M | $-43M | $-46M | · | $-40M | $-38M | $-35M | $-29M | $-25M | $-26M | · | $-18M | $-16M |
Bilanz 24
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $72M | $33M | $61M | $46M | $43M | $50M | $42M | $45M | $43M | $30M | $33M | $32M | $48M | $22M | $110M | $18M | |
| Prepaid Expense | $6M | $10M | $13M | $11M | $9M | $7M | $5M | $7M | $8M | $9M | $8M | $7M | $5M | $5M | $5M | $5M | |
| Current Assets | $472M | $510M | $543M | $574M | $603M | $443M | $475M | $499M | $519M | $541M | $298M | $317M | $333M | $357M | $370M | $253M | |
| PP&E (Net) | $7M | $7M | $8M | $8M | $9M | $9M | $10M | $10M | $10M | $10M | $11M | $11M | $10M | $9M | $5M | $2M | |
| PP&E (Gross) | $15M | $15M | $15M | $14M | $14M | $14M | $14M | $14M | $13M | $13M | $13M | $13M | $12M | $10M | $6M | $3M | |
| Accum. Depreciation | $8M | $7M | $7M | $6M | $6M | $5M | $5M | $4M | $4M | $3M | $2M | $2M | $1M | $1M | $977.0K | $882.0K | |
| Other Non-current Assets | · | · | · | · | · | $695.0K | $262.0K | $262.0K | $262.0K | · | $467.0K | $419.0K | $251.0K | $251.0K | $264.0K | $447.0K | |
| Total Assets | $480M | $519M | $553M | $583M | $613M | $454M | $487M | $511M | $532M | $554M | $311M | $331M | $346M | $367M | $377M | $257M | |
| Accounts Payable | $5M | $7M | $6M | $6M | $8M | $9M | $6M | $6M | $7M | $5M | $5M | $4M | $4M | $6M | $6M | $3M | |
| Accrued Liabilities | $5M | $9M | $8M | $6M | $6M | $7M | $7M | $6M | $5M | $6M | $6M | $7M | $6M | $6M | $5M | $4M | |
| Short-term Debt | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $7.0K | · | |
| Current Liabilities | $29M | $23M | $27M | $22M | $21M | $21M | $24M | $19M | $17M | $15M | $16M | $14M | $13M | $17M | $13M | $9M | |
| Capital Leases | $3M | $3M | $3M | $3M | $3M | $4M | $4M | $3M | $4M | $4M | $5M | $5M | $5M | $4M | $2M | $2M | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $192.0K | |
| Total Liabilities | $32M | $25M | $30M | $25M | $24M | $25M | $28M | $22M | $21M | $19M | $21M | $19M | $18M | $20M | $16M | $11M | |
| Long-term Debt | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $59.0K | · | |
| Total Debt | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $7.0K | · | |
| Common Stock | $10.0K | $10.0K | $10.0K | $10.0K | $10.0K | $9.0K | $9.0K | $9.0K | $9.0K | $9.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $5.0K | |
| Paid-in Capital | $1.10B | $1.09B | $1.07B | $1.05B | $1.04B | $849M | $837M | $827M | $816M | $809M | $505M | $501M | $497M | $493M | $489M | $356M | |
| Retained Earnings | $-653M | $-595M | $-546M | $-496M | $-455M | $-419M | $-379M | $-339M | $-305M | $-273M | $-215M | $-189M | $-167M | $-145M | $-125M | $-108M | |
| AOCI | $-500.0K | $-252.0K | $677.0K | $701.0K | $204.0K | $401.0K | $420.0K | $1M | $-1M | $-861.0K | $-424.0K | $-547.0K | $-251.0K | $-1M | $-2M | $-2M | |
| Stockholders' Equity | $448M | $493M | $522M | $559M | $589M | $430M | $459M | $489M | $510M | $535M | $290M | $311M | $329M | $347M | $361M | $246M | |
| Liabilities + Equity | $480M | $519M | $553M | $583M | $613M | $454M | $487M | $511M | $532M | $554M | $311M | $331M | $346M | $367M | $377M | $257M | |
| Shares Outstanding | 107,776,380 | 107,481,522 | 106,249,579 | 105,761,949 | 105,341,296 | 95,205,683 | 94,838,466 | 94,408,911 | 93,643,341 | 93,284,528 | 63,460,939 | 63,458,932 | 63,274,732 | 63,257,376 | 63,208,828 | 49,780,365 |
Cashflow 9
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $9M | $9M | $10M | $8M | $8M | $9M | $8M | $7M | $5M | $5M | $5M | $4M | $4M | $4M | $3M | $2M | |
| Operating Cash Flow | $-42M | $-43M | $-39M | $-35M | $-33M | $-38M | $-27M | $-27M | $-26M | $-29M | $-22M | $-20M | $-23M | $-12M | $-12M | $-16M | |
| CapEx | $32.0K | $260.0K | $73.0K | $89.0K | $50.0K | $44.0K | $274.0K | $520.0K | $221.0K | $297.0K | $457.0K | $759.0K | $4M | $3M | $1M | $554.0K | |
| Investing Cash Flow | $78M | $2M | $50M | $36M | $-162M | $44M | $21M | $25M | $37M | $-268M | $23M | $3M | $49M | $-76M | $-26M | $-46.0K | |
| Stock Issued | · | · | $0 | $0 | · | · | $0 | $0 | $0 | $239M | · | · | · | $-555.0K | · | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $239M | · | · | · | · | · | · | |
| Financing Cash Flow | $3M | $12M | $4M | $2M | $188M | $2M | $3M | $3M | $2M | $241M | $-211.0K | $369.0K | $21.0K | $-303.0K | $130M | $179.0K | |
| Net Change in Cash | $39M | $-28M | $15M | $3M | $-7M | $8M | $-3M | $1M | $13M | $-56M | $1M | $-16M | $26M | $-88M | $91M | $-16M | |
| Free Cash Flow | · | $-43M | · | · | · | · | · | · | · | $-29M | · | · | $-27M | · | · | · |
Rentabilität 2
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -10.5% | -10.1% | · | -7.4% | -6.3% | -8.1% | · | -8.3% | -7.3% | -6.3% | -7.5% | -7.3% | -7.4% | · | -5.2% | -5.7% | |
| ROE | -11.1% | -10.6% | · | -7.8% | -6.6% | -8.5% | · | -8.8% | -7.7% | -6.6% | -7.9% | -7.7% | -7.8% | · | -5.4% | -5.9% |
Liquidität & Solvenz 3
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 16.2 | 22.6 | · | 26.5 | 28.9 | 21.0 | · | 26.3 | 30.2 | 37.1 | 18.2 | 22.0 | 26.2 | · | 27.8 | 27.5 | |
| Quick Ratio | 2.5 | 1.5 | · | 2.1 | 2.1 | 2.4 | · | 2.4 | 2.5 | 2.1 | 2.0 | 2.2 | 3.8 | · | 8.2 | 2.0 | |
| Debt / Equity | · | · | · | · | · | · | · | · | · | · | · | · | · | · | 0.0 | · |
Bewertung (TTM) 10
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-183M | $-167M | · | $-152M | $-143M | $-135M | · | $-120M | $-107M | $-99M | $-88M | $-78M | $-71M | · | $-61M | $-54M | |
| Market Cap | $4.38B | $3.39B | · | $1.72B | $1.38B | $2.09B | · | $2.52B | $1.69B | $1.70B | $364M | $492M | $422M | · | $622M | $396M | |
| Enterprise Value | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $512M | · | |
| P/E | -23.6 | -19.4 | · | -10.7 | -8.9 | -15.1 | · | -18.5 | -12.7 | -12.7 | -4.0 | -5.7 | -5.1 | · | -8.1 | -7.3 | |
| P/B | 9.8 | 6.9 | · | 3.1 | 2.3 | 4.9 | · | 5.2 | 3.3 | 3.2 | 1.3 | 1.6 | 1.3 | · | 1.7 | 1.6 | |
| P / Tangible Book | 9.8 | 6.9 | · | 3.1 | 2.3 | 4.9 | · | 5.2 | 3.3 | 3.2 | 1.3 | 1.6 | 1.3 | · | 1.7 | 1.6 | |
| P / Cash Flow | · | -79.6 | · | · | · | -55.3 | · | · | · | -59.5 | · | · | -18.5 | · | · | · | |
| P / FCF | · | -79.1 | · | · | · | · | · | · | · | -58.9 | · | · | -15.5 | · | · | · | |
| EV / EBITDA | · | · | · | · | · | · | · | · | · | · | · | · | · | · | -28.0 | · | |
| Earnings Yield | -4.2% | -5.1% | · | -9.4% | -11.2% | -6.6% | · | -5.4% | -7.9% | -7.9% | -25.3% | -17.5% | -19.8% | · | -12.4% | -13.7% |
Finanzberichte Gewinn- und Verlustrechnung, Bilanz, Cashflow — jährlich, letzte 5 Jahre
Gewinn- und Verlustrechnung
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Nettoergebnis | $-168M | $-134M | $-100M | $-68M | $-43M |
| Verwässerte EPS | $-1.63 | $-1.45 | $-1.57 | $-1.26 | $-1.14 |
Bilanz
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Liquiditätsgrad | 19.9 | 19.9 | 19.5 | 21.5 | 27.0 |
| Quick Ratio | 2.2 | 1.7 | 5.1 | 1.3 | 1.5 |
Cashflow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Freier Cashflow | $-144M | $-110M | $-98M | $-58M | $-34M |
Meine Kennzahlen Ihre persönliche Watchlist — ausgewählte Zeilen aus den vollständigen Fundamentaldaten
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Wählen Sie die Kennzahlen, die für Sie wichtig sind — klicken Sie auf das ➕ neben jeder Zeile in den vollständigen Fundamentaldaten oben.
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Institutionelle Eigentümer (13F) 249 Einreicher · $4.0B gesamt · Stand 30. Juni 2026
Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.
Institutionelle Aktivität — Q2 2026 vs. Vorquartal
| Neue Positionen | Geschlossene Positionen | Erhöht | Abgenommen | Nettoveränderung der Aktien |
|---|---|---|---|---|
| 47 (+1 vs. Vorquartal) | 24 (+1 vs. Vorquartal) | 79 (+12 vs. Vorquartal) | 74 (+9 vs. Vorquartal) | +3.3M |
Verglichen mit Q1 2026. SEC-Formular 13F-Einreichungen sind innerhalb von 45 Tagen nach Quartalsende fällig, zuzüglich einer kurzen Pufferzeit für verspätete Einreicher — Quartale, die noch in diesem Fenster liegen, werden zugunsten des letzten vollständig berichteten Paares übersprungen.
| Institution | Wert | Aktien | % der verfolgten 13F | Typ |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | $630.516.330 | 15.518.492 | 15,63% | Aktien |
| Paradigm Biocapital Advisors LP | $415.053.937 | 10.215.455 | 10,29% | Aktien |
| RA CAPITAL MANAGEMENT, L.P. | $340.996.620 | 8.392.730 | 8,46% | Aktien |
| NOVO HOLDINGS A/S | $217.370.500 | 5.350.000 | 5,39% | Aktien |
| Driehaus Capital Management LLC | $192.123.952 | 4.728.623 | 4,76% | Aktien |
| PERCEPTIVE ADVISORS LLC | $177.714.564 | 4.373.974 | 4,41% | Aktien |
| VANGUARD CAPITAL MANAGEMENT LLC | $156.859.022 | 3.860.670 | 3,89% | Aktien |
| BAKER BROS. ADVISORS LP | $150.400.843 | 3.701.719 | 3,73% | Aktien |
| Siren, L.L.C. | $129.391.476 | 3.184.629 | 3,21% | Aktien |
| FMR LLC | $107.911.899 | 2.655.966 | 2,68% | Aktien |
| Cormorant Asset Management, LP | $101.981.300 | 2.510.000 | 2,53% | Aktien |
| Integral Health Asset Management, LLC | $81.260.000 | 2.000.000 | 2,01% | Aktien |
| BRAIDWELL LP | $81.136.688 | 1.996.965 | 2,01% | Aktien |
| GEODE CAPITAL MANAGEMENT, LLC | $77.257.283 | 1.901.081 | 1,92% | Aktien |
| STATE STREET CORP | $74.268.674 | 1.827.927 | 1,84% | Aktien |
| ALLIANCEBERNSTEIN L.P. | $66.749.256 | 2.119.024 | 1,66% | Aktien |
| MPM BIOIMPACT LLC | $65.852.291 | 1.620.780 | 1,63% | Aktien |
| MORGAN STANLEY | $65.647.597 | 1.615.742 | 1,63% | Aktien |
| BANK OF AMERICA CORP /DE/ | $56.886.145 | 1.400.102 | 1,41% | Aktien |
| Qube Research & Technologies Ltd | $50.889.359 | 1.252.507 | 1,26% | Aktien |
| AMERICAN CENTURY COMPANIES INC | $45.793.233 | 1.127.078 | 1,14% | Aktien |
| First Light Asset Management, LLC | $44.496.798 | 1.095.171 | 1,10% | Aktien |
| DIMENSIONAL FUND ADVISORS LP | $43.383.658 | 1.067.774 | 1,08% | Aktien |
| VICTORY CAPITAL MANAGEMENT INC | $36.683.608 | 902.870 | 0,91% | Aktien |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $31.953.707 | 786.456 | 0,79% | Aktien |
| Aberdeen Group plc | $26.325.233 | 647.926 | 0,65% | Aktien |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $25.212.215 | 620.532 | 0,63% | Aktien |
| Tyro Capital Management LLC | $24.904.768 | 612.965 | 0,62% | Aktien |
| Parkman Healthcare Partners LLC | $23.444.973 | 577.036 | 0,58% | Aktien |
| Artisan Partners Limited Partnership | $23.359.203 | 574.925 | 0,58% | Aktien |
| VANGUARD FIDUCIARY TRUST CO | $22.276.820 | 548.285 | 0,55% | Aktien |
| NORGES BANK | $20.726.988 | 510.140 | 0,51% | Aktien |
| Opaleye Management Inc. | $20.315.000 | 500.000 | 0,50% | Aktien |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $18.771.060 | 462.000 | 0,47% | Aktien |
| Soleus Capital Management, L.P. | $18.319.620 | 450.889 | 0,45% | Aktien |
| New Leaf Venture Partners, L.L.C. | $16.709.211 | 1.030.161 | 0,41% | Aktien |
| GOLDMAN SACHS GROUP INC | $15.838.224 | 389.816 | 0,39% | Aktien |
| Sofinnova Investments, Inc. | $15.476.901 | 380.923 | 0,38% | Aktien |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $13.570.989 | 334.014 | 0,34% | Aktien |
| CITADEL ADVISORS LLC | $13.539.054 | 333.228 | 0,34% | Aktien |
| Squadron Capital Management LLC | $11.782.700 | 290.000 | 0,29% | Aktien |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $11.511.820 | 283.333 | 0,29% | Aktien |
| DIADEMA PARTNERS LP | $11.060.055 | 272.214 | 0,27% | Aktien |
| KENNEDY CAPITAL MANAGEMENT LLC | $10.425.983 | 256.608 | 0,26% | Aktien |
| Schonfeld Strategic Advisors LLC | $10.368.855 | 255.202 | 0,26% | Aktien |
| DAFNA Capital Management LLC | $9.215.656 | 226.819 | 0,23% | Aktien |
| Woodline Partners LP | $9.112.903 | 224.290 | 0,23% | Aktien |
| PRUDENTIAL FINANCIAL INC | $9.053.380 | 222.825 | 0,22% | Aktien |
| PEREGRINE CAPITAL MANAGEMENT LLC | $8.067.899 | 198.570 | 0,20% | Aktien |
| SEB Asset Management AB | $7.884.765 | 194.063 | 0,20% | Aktien |
| Granahan Investment Management, LLC | $7.873.200 | 193.778 | 0,20% | Aktien |
| BARCLAYS PLC | $7.694.956 | 189.391 | 0,19% | Aktien |
| D. E. Shaw & Co., Inc. | $6.616.027 | 162.836 | 0,16% | Aktien |
| Caption Management, LLC | $6.480.485 | 159.500 | 0,16% | Kaufoption |
| ADAR1 Capital Management, LLC | $5.818.175 | 143.199 | 0,14% | Aktien |
| KVP Capital Advisors, LP | $5.403.790 | 133.000 | 0,13% | Aktien |
| NEUBERGER BERMAN GROUP LLC | $5.201.900 | 128.031 | 0,13% | Aktien |
| Point72 Asset Management, L.P. | $4.764.355 | 117.262 | 0,12% | Aktien |
| Quantum Private Wealth, LLC | $4.606.640 | 113.380 | 0,11% | Aktien |
| ALPS ADVISORS INC | $4.420.341 | 108.795 | 0,11% | Aktien |
| Moody Aldrich Partners LLC | $4.264.200 | 104.952 | 0,11% | Aktien |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | $4.063.000 | 100.000 | 0,10% | Verkaufsoption |
| Artia Global Partners LP | $4.014.244 | 98.800 | 0,10% | Aktien |
| Nuveen, LLC | $3.934.203 | 96.830 | 0,10% | Aktien |
| Swiss National Bank | $3.932.984 | 96.800 | 0,10% | Aktien |
| HighVista Strategies LLC | $3.697.168 | 90.996 | 0,09% | Aktien |
| BlackRock, Inc. | $3.668.036 | 90.279 | 0,09% | Aktien |
| RHUMBLINE ADVISERS | $3.666.114 | 90.232 | 0,09% | Aktien |
| JANUS HENDERSON GROUP PLC | $3.597.171 | 114.215 | 0,09% | Aktien |
| Ally Bridge Group (NY) LLC | $3.384.479 | 83.300 | 0,08% | Aktien |
| BOOTHBAY FUND MANAGEMENT, LLC | $3.361.482 | 82.734 | 0,08% | Aktien |
| NEW YORK STATE COMMON RETIREMENT FUND | $3.258.404 | 80.197 | 0,08% | Aktien |
| Centiva Capital, LP | $3.047.250 | 75.000 | 0,08% | Kaufoption |
| Jefferies Financial Group Inc. | $2.900.535 | 71.389 | 0,07% | Aktien |
| Persistent Asset Partners Ltd | $2.821.388 | 69.441 | 0,07% | Aktien |
| Bank of New York Mellon Corp | $2.805.298 | 69.045 | 0,07% | Aktien |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $2.638.000 | 64.918 | 0,07% | Aktien |
| TUDOR INVESTMENT CORP ET AL | $2.313.228 | 56.934 | 0,06% | Aktien |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2.312.699 | 73.419 | 0,06% | Aktien |
| STATE OF WISCONSIN INVESTMENT BOARD | $2.312.253 | 56.910 | 0,06% | Aktien |
| CITADEL ADVISORS LLC | $2.263.091 | 55.700 | 0,06% | Kaufoption |
| CITIGROUP INC | $2.252.324 | 55.435 | 0,06% | Aktien |
| HighMark Wealth Management LLC | $2.160.662 | 53.179 | 0,05% | Aktien |
| TWO SIGMA INVESTMENTS, LP | $2.013.135 | 49.548 | 0,05% | Aktien |
| ALGERT GLOBAL LLC | $1.919.361 | 47.240 | 0,05% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.913.673 | 47.100 | 0,05% | Verkaufsoption |
| XTX Topco Ltd | $1.862.154 | 45.832 | 0,05% | Aktien |
| BNP PARIBAS FINANCIAL MARKETS | $1.770.940 | 43.587 | 0,04% | Aktien |
| MetLife Investment Management, LLC | $1.698.497 | 41.804 | 0,04% | Aktien |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1.655.957 | 40.757 | 0,04% | Aktien |
| Ensign Peak Advisors, Inc | $1.640.599 | 40.379 | 0,04% | Aktien |
| Knights of Columbus Asset Advisors LLC | $1.569.984 | 38.641 | 0,04% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.568.318 | 38.600 | 0,04% | Kaufoption |
| Aquatic Capital Management LLC | $1.499.978 | 36.918 | 0,04% | Aktien |
| VANGUARD ASSET MANAGEMENT, Ltd | $1.452.279 | 35.744 | 0,04% | Aktien |
| Vanguard Global Advisers, LLC | $1.434.361 | 35.303 | 0,04% | Aktien |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1.338.312 | 32.939 | 0,03% | Aktien |
| JANE STREET GROUP, LLC | $1.178.676 | 29.010 | 0,03% | Aktien |
| Invesco Ltd. | $1.158.077 | 28.503 | 0,03% | Aktien |
| Verdad Advisers, LP | $1.106.517 | 27.234 | 0,03% | Aktien |
Unternehmensinsider 15 Insider · 0 Führungskräfte · 7 Direktoren
| Insider | Rolle | Letzte Aktivität | Gehaltene Aktien | Käufe 12m | Verkäufe 12m | Netto 12m |
|---|---|---|---|---|---|---|
| Jonathan C Fox | Direktor | 1. Juli 2026 A | 24.833 | 0 | 0 | $0 |
| Christopher Nathan Martin | Direktor | 5. Juni 2026 A | — | 0 | 0 | $0 |
| Badreddin Edris | Direktor | 5. Juni 2026 A | — | 0 | 0 | $0 |
| Laura Brege | Direktor | 5. Juni 2026 A | — | 0 | 0 | $0 |
| Arlene Morris | Direktor | 5. Juni 2026 A | — | 0 | 0 | $0 |
| Peter A. Thompson | Direktor | 5. Juni 2026 A | 443.792 | 0 | 0 | $0 |
| Jonathan D Root | Direktor | 5. Juni 2026 A | 0 | 0 | 0 | $0 |
| Novo Holdings A/S | 10%-Eigentümer | 14. September 2022 P | 6.071.703 | 0 | 0 | $0 |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | 10%-Eigentümer | 30. März 2021 C | 681.812 | 0 | 0 | $0 |
| Alan J Russell | — | 12. August 2026 A | 31.466 | 0 | 5 | $-8.140.060 |
| Behrad Derakhshan | — | 12. August 2026 A | 31.826 | 0 | 4 | $-223.420 |
| Michael Nofi | — | 12. August 2026 A | — | 0 | 0 | $0 |
| Joanne M. Donovan | — | 12. August 2026 A | 8.625 | 0 | 5 | $-412.712 |
| John R Moore | — | 12. August 2026 A | 17.697 | 0 | 4 | $-219.831 |
| Kevin Koch | — | 12. August 2026 A | 52.488 | 0 | 3 | $-785.049 |
Insider aus SEC-Einreichungen Form 3/4/5; Netto = nur P/S aus offenen Märkten
Aktivisten & 5%+-Eigentümer 3 Beteiligungen
Investoren mit SEC Schedule 13D — wirtschaftliches Eigentum über 5% mit der Absicht, Einfluss auf den Emittenten zu nehmen (aktivistische Beteiligungen, Board-Kampagnen, M&A). Jede Zeile zeigt den zuletzt bekannten Stand der Position dieses Melders.
| Anmelder | Eingereicht | Beteiligung | Status | Zweck | Einreichung |
|---|---|---|---|---|---|
| Novo Holdings A/S ×7 Einreichungen | 27. April 2026 | 4,90% | Änderung | — | SEC |
| ORBIMED ADVISORS LLC, ORBIMED CAPITAL GP VI LLC, OrbiMed Genesis GP LLC, ORBIMED CAPITAL LLC ×5 Einreichungen | 12. Mai 2025 | 14,50% | Änderung | — | SEC |
| U.S. Venture Partners XI, L.P. (“USVP XI”), Presidio Management Group XI, L.L.C. (“PMG XI”), Casey M. Tansey, Jonathan D. Root ×2 Einreichungen | 1. Februar 2023 | — | Erste Einreichung | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF-Besitz Gehalten von 45 ETFs
Gewichtung spiegelt nur direkte Aktienbestände (N-PORT) wider; gehebelte oder derivatbasierte Fonds können zusätzliche Swap-Exposure halten, die hier nicht angezeigt wird.
| Fonds | Gewicht | Anteile | Stand | Quelle |
|---|---|---|---|---|
| IBRN · iShares Trust | 3,54% | 6.153 SH | 8. August 2026 | Täglich |
| SBIO · ALPS ETF Trust | 2,33% | 110.576 NS | 31. Mai 2026 | N-PORT |
| PILL · Direxion Shares ETF Trust | 1,34% | 5.567 NS | 30. April 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,97% | 11.685 NS | 30. April 2026 | N-PORT |
| IHE · iShares Trust | 0,74% | 269.166 SH | 8. August 2026 | Täglich |
| MMSC · First Trust Exchange-Traded Fund VI… | 0,63% | 9.620 NS | 31. Mai 2026 | N-PORT |
| DWAS · Invesco Exchange-Traded Fund Trust … | 0,47% | 48.340 SH | 8. August 2026 | Täglich |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,32% | 5.857 SH | 8. August 2026 | Täglich |
| IBB · iShares Trust | 0,27% | 577.144 SH | 8. August 2026 | Täglich |
| IWO · iShares Trust | 0,20% | 647.964 SH | 8. August 2026 | Täglich |
| BIB · ProShares Trust | 0,18% | 3.966 NS | 31. Mai 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,17% | 76.681 SH | 8. August 2026 | Täglich |
| VFMO · VANGUARD WELLINGTON FUND | 0,13% | 65.171 SH | 8. August 2026 | Täglich |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,13% | 30.264 NS | 30. April 2026 | N-PORT |
| IWM · iShares Trust | 0,10% | 1.809.565 SH | 8. August 2026 | Täglich |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,09% | 411.642 SH | 8. August 2026 | Täglich |
| ESML · iShares Trust | 0,06% | 42.227 SH | 8. August 2026 | Täglich |
| RSSL · Global X Funds | 0,06% | 29.238 NS | 30. April 2026 | N-PORT |
| ISCG · iShares Trust | 0,06% | 13.816 SH | 8. August 2026 | Täglich |
| ISCB · iShares Trust | 0,06% | 3.892 SH | 8. August 2026 | Täglich |
| ISCV · iShares Trust | 0,06% | 9.273 SH | 8. August 2026 | Täglich |
| ITWO · ProShares Trust | 0,06% | 3.175 NS | 31. Mai 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,05% | 355.389 NS | 31. Mai 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,05% | 30.883 SH | 8. August 2026 | Täglich |
| DFAS · Dimensional ETF Trust | 0,04% | 167.330 NS | 30. April 2026 | N-PORT |
| UWM · ProShares Trust | 0,03% | 2.484 NS | 31. Mai 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,03% | 864.416 SH | 8. August 2026 | Täglich |
| VHT · VANGUARD WORLD FUND | 0,03% | 145.298 SH | 8. August 2026 | Täglich |
| FHLC · FIDELITY COVINGTON TRUST | 0,03% | 24.144 NS | 30. April 2026 | N-PORT |
| URTY · ProShares Trust | 0,02% | 2.510 NS | 31. Mai 2026 | N-PORT |
| WSML · iShares Trust | 0,02% | 3.101 SH | 8. August 2026 | Täglich |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 2.733 NS | 31. Mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 33.343 NS | 31. Mai 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,01% | 2.902.915 SH | 8. August 2026 | Täglich |
| HDG · ProShares Trust | 0,01% | 63 NS | 31. Mai 2026 | N-PORT |
| TILT · FlexShares Trust | 0,01% | 5.888 NS | 30. April 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,01% | 7.155 NS | 31. Mai 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,01% | 105.864 NS | 30. April 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,01% | 6.245 NS | 30. April 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 105.818 SH | 8. August 2026 | Täglich |
| IWV · iShares Trust | 0,00% | 20.898 SH | 8. August 2026 | Täglich |
| DFAU · Dimensional ETF Trust | 0,00% | 15.310 NS | 30. April 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 44.236 NS | 31. Mai 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 9.382 NS | 30. April 2026 | N-PORT |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 5.890 SH | 8. August 2026 | Täglich |