PMN ProMIS Neurosciences Inc. - Common Shares
NASDAQ · Biotechnology · View on SEC EDGAR ↗ close Oct 2, 2026 10-K/10-Q Aug 13, 2026
$9.40
· of 52w range
· above low
· to high
$0.3652w low
$27.4052w high
Market Cap (MRQ)
$84M
P/E
-0.4
EPS
$-22.61
your badges
52W Range
$0–$27
Analyst Rating
BUY
Price Target
$43
P/E
-0.4
ROE
4840.3%
Net Profit Margin
·
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PMN Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$9.40
Market Cap (MRQ)
$84M
P/E
-0.4
EPS
$-22.61
ROE
4840.3%
52W Range
$0–$27
PMN Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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Stock splits
| Ex-date | Split | Type |
|---|---|---|
| Nov. 28, 2025 | 1-for-25 | Reverse |
| June 28, 2022 | 1-for-60 | Reverse |
10-Year Performance Revenue, net income, margins and EPS trends
EPS$-22.612021-12-31 → 2025-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | PMN | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E | -0.45Y avg ≈-0.7 | ≈-0.7 | · | · | |
| P/B (MRQ) | 1.75Y avg ≈-1.3 | ≈-1.3 | 3.5 | Undervalued | |
| Price / Cash Flow | -0.75Y avg ≈-1.2 | ≈-1.2 | · | · | |
| Price / Tangible Book | 2.6 | · | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | PMN | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| ROA | -282.8%5Y avg ≈-131.4% | ≈-131.4% | · | · | |
| ROE | 4840.3%5Y avg ≈1537.4% | ≈1537.4% | · | · |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | PMN | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio (MRQ) | 7.95Y avg ≈3.6 | ≈3.6 | 9.0 | Low liquidity | |
| Quick Ratio | 0.65Y avg ≈2.6 | ≈2.6 | 8.6 | Low liquidity |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-7.4%
Next Report
Nov 10, 2026
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | Aug 13, 2026 | $-1.28 | $-1.39 | 8.1% |
| March 31, 2026 | May 11, 2026 | $-1.26 | $-1.49 | 15.5% |
| Dec. 31, 2025 | $-6.57 | $-4.93 | -33.4% | |
| Sept. 30, 2025 | $-6.00 | $-6.14 | 2.3% | |
| June 30, 2025 | $-7.25 | $-4.42 | -64.1% | |
| March 31, 2025 | $-5.25 | $-3.03 | -73.3% | |
| Dec. 31, 2024 | $-0.25 | $-3.54 | 92.9% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| R&D Expense | $33M | $11M | $8M | $16M | $5M | |
| SG&A Expense | $7M | $6M | $6M | $7M | $4M | |
| Operating Expenses | $40M | $17M | $14M | $23M | $8M | |
| Operating Income | $-40M | $-17M | $-14M | $-23M | $-8M | |
| Other Non-op | $442.6K | $626.2K | $384.9K | $115.5K | $12.9K | |
| Income Tax | · | $0 | $0 | $0 | · | |
| Net Income | $-40M | $3M | $-13M | $-18M | $-10M | |
| EPS (Basic) | $-22.61 | $2.68 | $-1.07 | $-2.41 | $-1.69 | |
| EPS (Diluted) | $-22.61 | $2.63 | $-1.07 | $-2.41 | $-1.69 | |
| Shares (Basic) | 1,756,844 | 1,036,799 | 12,292,707 | 7,502,609 | 5,785,617 | |
| Shares (Diluted) | 1,756,844 | 1,058,469 | 12,292,707 | 7,502,609 | 5,785,617 | |
| EBITDA | $-40M | $-17M | $-14M | · | · |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Cash & Equivalents | $6M | $13M | $13M | $6M | $17M | |
| Short-term Investments | $33.8K | $33.1K | $32.4K | $31.0K | $33.2K | |
| Prepaid Expense | $3M | $6M | $988.6K | $996.7K | $737.3K | |
| Current Assets | $9M | $19M | $14M | $7M | $18M | |
| PP&E (Net) | · | · | · | $321 | $4.7K | |
| PP&E (Gross) | · | · | · | $80.3K | $84.1K | |
| Accum. Depreciation | · | · | · | $80.0K | $79.4K | |
| Intangibles | · | · | · | $20.8K | $27.6K | |
| Total Assets | $9M | $19M | $14M | $7M | $18M | |
| Accounts Payable | $3M | $2M | $8M | $3M | $409.0K | |
| Accrued Liabilities | $8M | $481.0K | $2M | $3M | $520.1K | |
| Current Liabilities | $10M | $2M | $9M | $6M | $929.1K | |
| Total Liabilities | $10M | $2M | $10M | $8M | $12M | |
| Long-term Debt | · | · | $0 | · | $4M | |
| Common Stock | · | · | · | · | $0 | |
| Paid-in Capital | $130M | $108M | $98M | $79M | $68M | |
| Retained Earnings | $-130M | $-91M | $-93M | $-80M | $-62M | |
| AOCI | $-371.2K | $-371.2K | $-371.2K | $-195.4K | $-187.9K | |
| Stockholders' Equity | $-1M | $16M | $4M | $-1M | $6M | |
| Liabilities + Equity | $9M | $19M | $14M | $7M | $18M | |
| Shares Outstanding | 2,152,397 | 1,307,520 | 18,885,254 | 8,579,284 | 7,195,529 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Stock-based Comp | $857.6K | $825.8K | $271.5K | $487.6K | $515.6K | |
| Amort. of Intangibles | · | · | $20.8K | $5.1K | $5.2K | |
| Operating Cash Flow | $-28M | $-27M | $-11M | $-17M | $-9M | |
| CapEx | · | · | · | $2.0K | $6.0K | |
| Investing Cash Flow | $-702 | $-693 | $-1.3K | $-2.0K | $94.6K | |
| Stock Issued | $708.5K | $190.3K | · | $5M | $16M | |
| Net Stock Activity | $708.5K | $190.3K | · | · | · | |
| Financing Cash Flow | $21M | $28M | $18M | $6M | $26M | |
| Net Change in Cash | $-7M | $693.0K | $7M | $-11M | $16M |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| ROA | -282.8% | 17.1% | -128.6% | · | · | |
| ROE | 4840.3% | 23.4% | -251.5% | · | · |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Current Ratio | 0.9 | 8.5 | 1.5 | · | · | |
| Quick Ratio | 0.6 | 6.0 | 1.4 | · | · |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Book Value / Share | $-0.58 | $0.50 | $0.20 | · | · | |
| Cash Flow / Share | $-16.01 | $-1.03 | $-0.88 | · | · | |
| Cash / Share | $2.84 | $0.41 | $0.67 | · | · | |
| EPS (TTM) | $-22.61 | $2.63 | $-1.07 | $-2.41 | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Net Income TTM | $-40M | $3M | $-13M | $-18M | · | |
| Market Cap | $15M | $31M | $22M | · | · | |
| P/E | -0.3 | 0.4 | -1.1 | -1.8 | · | |
| P/B | -11.7 | 1.9 | 5.8 | · | · | |
| P / Tangible Book | · | 1.9 | 5.8 | · | · | |
| P / Cash Flow | -0.5 | -1.1 | -2.0 | · | · | |
| Earnings Yield | -331.0% | 276.8% | -93.0% | -55.5% | · |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $10M | $7M | $9M | $10M | $9M | $5M | $4M | $3M | $2M | $2M | $2M | $1M | $1M | $4M | $6M | $5M | |
| SG&A Expense | $3M | $2M | $1M | $2M | $1M | $2M | $2M | $2M | $1M | $2M | $2M | $1M | $2M | $1M | $2M | $1M | |
| Operating Expenses | $12M | $9M | $11M | $12M | $10M | $7M | $6M | $4M | $3M | $4M | $4M | $3M | $3M | $5M | $9M | $6M | |
| Operating Income | $-12M | $-9M | $-11M | $-12M | $-10M | $-7M | $-6M | $-4M | $-3M | $-4M | $-4M | $-3M | $-3M | $-5M | $-9M | $-6M | |
| Interest Expense | · | · | · | · | · | · | · | $1 | $-1 | $76.8K | · | $75.4K | $49.2K | · | · | $0 | |
| Other Non-op | $536.7K | $400.5K | $92.4K | $170.3K | $67.6K | $112.2K | $-13M | $14M | $90.0K | $41.6K | $144.2K | $156.9K | $30.9K | $52.9K | $52.6K | $35.9K | |
| Net Income | $-12M | $-8M | $-11M | $-12M | $-10M | $-7M | $-238.2K | $9M | $-3M | $-4M | $-4M | $-2M | $-2M | $-5M | $-7M | $-6M | |
| EPS (Basic) | $-1.28 | $-1.26 | $-21.87 | $-0.24 | $-7.26 | $-5.27 | $2.69 | $0.31 | $-0.13 | $-0.19 | $-0.03 | $-0.19 | $-0.27 | $-0.58 | $-0.91 | $-0.83 | |
| EPS (Diluted) | $-1.28 | $-1.26 | $-21.87 | $-0.24 | $-7.26 | $-5.27 | $2.64 | $0.31 | $-0.13 | $-0.19 | $-0.03 | $-0.19 | $-0.27 | $-0.58 | $-0.91 | $-0.83 | |
| Shares (Basic) | 9,142,366 | 6,527,779 | · | 48,833,799 | 1,394,048 | 1,394,048 | · | 30,023,675 | 19,770,739 | 19,533,976 | · | 12,370,830 | 8,579,284 | 8,579,284 | · | 7,195,529 | |
| Shares (Diluted) | 9,142,366 | 6,527,779 | · | 48,833,799 | 1,394,048 | 1,394,048 | · | 30,067,095 | 19,770,739 | 19,533,976 | · | 12,370,830 | 8,579,284 | 8,579,284 | · | 7,195,529 | |
| EBITDA | $-12M | $-9M | · | $-12M | $-10M | $-7M | · | $-4M | $-3M | $-4M | · | $-3M | $-3M | $-5M | · | $-6M |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $53M | $64M | $6M | $15M | $5M | $8M | $13M | $22M | $992.5K | $2M | $13M | $17M | $1M | $3M | $6M | $4M | |
| Short-term Investments | $33.8K | $33.8K | $33.8K | $33.1K | $33.1K | $33.1K | $33.1K | $32.4K | $32.4K | $32.4K | $32.4K | $31.8K | $31.8K | $31.1K | $31.0K | $30.5K | |
| Prepaid Expense | $3M | $2M | $3M | $6M | $5M | $5M | $6M | $3M | $384.8K | $1M | $988.6K | $957.8K | $224.7K | $1M | $996.7K | $1M | |
| Current Assets | $57M | $66M | $9M | $21M | $10M | $14M | $19M | $25M | $1M | $4M | $14M | $18M | $1M | $4M | $7M | $5M | |
| PP&E (Net) | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $321 | $788 | |
| PP&E (Gross) | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $79.1K | |
| Accum. Depreciation | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $78.3K | |
| Intangibles | · | · | · | · | · | · | · | · | · | · | · | $18.0K | $18.8K | $19.7K | $20.8K | $21.7K | |
| Total Assets | $57M | $67M | $9M | $21M | $10M | $14M | $19M | $25M | $1M | $4M | $14M | $18M | $1M | $4M | $7M | $5M | |
| Accounts Payable | $2M | $2M | $3M | $4M | $3M | $1M | $2M | $2M | $2M | $1M | $8M | $8M | $8M | $7M | $3M | $2M | |
| Accrued Liabilities | $5M | $5M | $8M | $8M | $7M | $3M | $481.0K | $1M | $1M | $1M | $2M | $1M | $775.9K | $2M | $3M | $1M | |
| Current Liabilities | $7M | $7M | $10M | $12M | $10M | $4M | $2M | $3M | $3M | $3M | $9M | $10M | $9M | $9M | $6M | $3M | |
| Total Liabilities | $7M | $7M | $10M | $12M | $10M | $4M | $2M | $17M | $4M | $3M | $10M | $11M | $10M | $11M | $8M | $5M | |
| Common Stock | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | |
| Paid-in Capital | $200M | $200M | $130M | $129M | $108M | $108M | $108M | $98M | $98M | $98M | $98M | $97M | $79M | $79M | $79M | $74M | |
| Retained Earnings | $-150M | $-139M | $-130M | $-120M | $-108M | $-98M | $-91M | $-90M | $-100M | $-97M | $-93M | $-90M | $-88M | $-85M | $-80M | $-73M | |
| AOCI | $-371.2K | $-371.2K | $-371.2K | $-371.2K | $-371.2K | $-371.2K | $-371.2K | $-371.2K | $-371.2K | $-371.2K | $-371.2K | $-371.2K | $-371.2K | $-199.7K | $-195.4K | $-270.3K | |
| Stockholders' Equity | $49M | $61M | $-1M | $9M | $-382.6K | $9M | $16M | $7M | $-2M | $77.1K | $4M | $7M | $-9M | $-6M | $-1M | $729.8K | |
| Liabilities + Equity | $57M | $67M | $9M | $21M | $10M | $14M | $19M | $25M | $1M | $4M | $14M | $18M | $1M | $4M | $7M | $5M | |
| Shares Outstanding | 8,967,693 | 8,967,693 | 2,152,397 | 53,811,110 | 32,689,190 | 32,689,190 | 1,307,520 | 32,689,190 | 18,961,116 | 18,961,116 | 18,885,254 | 18,525,254 | 8,579,284 | 8,579,284 | 8,579,284 | 7,195,529 |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $408.9K | $189.4K | $203.2K | $197.1K | $212.0K | $245.3K | $623.2K | $121.0K | $18.0K | $63.6K | $4.8K | $0 | $134.2K | $132.5K | $138.8K | $108.6K | |
| Amort. of Intangibles | · | · | · | · | · | · | · | · | · | · | $18.0K | $345 | $1.2K | $1.2K | $1.2K | $1.3K | |
| Operating Cash Flow | $-10M | $-12M | $-9M | $-10M | $-4M | $-5M | $-9M | $-7M | $-2M | $-10M | $-4M | $-2M | $-2M | $-3M | $-5M | $-5M | |
| CapEx | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $-43 | $-24 | |
| Investing Cash Flow | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $43 | $24 | |
| Stock Issued | · | · | $0 | · | · | · | $0 | $0 | $0 | $190.3K | · | · | · | · | · | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $190.3K | · | · | · | · | · | · | |
| Financing Cash Flow | $0 | $70M | $-1 | · | · | · | $470.0K | $27M | $0 | $190.3K | $-510.6K | · | · | · | · | · | |
| Net Change in Cash | $-10M | $58M | $-9M | $11M | $-4M | $-5M | $-8M | $21M | $-2M | $-10M | $-4M | $16M | $-2M | $-3M | $2M | $-5M |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -35.4% | -20.3% | · | -50.4% | -185.3% | -85.5% | · | 43.8% | -180.5% | -91.1% | · | -20.3% | -39.6% | -224.0% | · | -221.4% | |
| ROE | -47.9% | -23.5% | · | -140.7% | 760.8% | -153.9% | · | 132.2% | 48.6% | 119.2% | · | -63.1% | 254.3% | 160.5% | · | -1632.6% |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 7.9 | 9.9 | · | 1.8 | 1.0 | 3.4 | · | 9.3 | 0.4 | 1.3 | · | 1.8 | 0.2 | 0.5 | · | 1.7 | |
| Quick Ratio | 7.4 | 9.7 | · | 1.3 | 0.5 | 2.1 | · | 8.2 | 0.3 | 1.0 | · | 1.7 | 0.1 | 0.4 | · | 1.3 | |
| Interest Coverage | · | · | · | · | · | · | · | · | · | -47.9 | · | · | · | · | · | · |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $5.51 | $6.77 | · | $0.17 | $-0.01 | $0.29 | · | $0.22 | $-0.12 | $0.00 | · | $0.36 | $-0.99 | $-0.72 | · | $0.10 | |
| Cash Flow / Share | · | $-1.90 | · | · | · | $-0.14 | · | · | · | $-0.53 | · | · | · | $-0.30 | · | · | |
| Cash / Share | $5.96 | $7.12 | · | $0.29 | $0.14 | $0.26 | · | $0.66 | $0.05 | $0.13 | · | $0.91 | $0.14 | $0.39 | · | $0.54 | |
| EPS (TTM) | $-24.65 | $-30.63 | · | $-10.13 | $-9.58 | $-2.45 | · | $-0.04 | $-0.54 | $-0.68 | · | $-1.95 | $-2.59 | $-2.70 | · | $-1.75 |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-42M | $-41M | · | $-29M | $-8M | $-933.9K | · | $-563.3K | $-12M | $-12M | · | $-17M | $-20M | $-21M | · | $-13M | |
| Market Cap | $118M | $114M | · | $23M | $16M | $23M | · | $41M | $28M | $36M | · | $37M | $33M | $41M | · | $44M | |
| P/E | -0.5 | -0.4 | · | -0.0 | -0.1 | -0.3 | · | -31.2 | -2.8 | -2.8 | · | -1.0 | -1.5 | -1.8 | · | -3.5 | |
| P/B | 2.4 | 1.9 | · | 2.5 | -41.0 | 2.4 | · | 5.6 | -12.5 | 469.7 | · | 5.4 | -3.9 | -6.6 | · | 60.4 | |
| P / Tangible Book | 2.4 | 1.9 | · | 2.5 | · | 2.4 | · | 5.6 | · | 469.7 | · | 5.4 | · | · | · | 62.3 | |
| P / Cash Flow | · | -9.2 | · | · | · | -4.6 | · | · | · | -3.5 | · | · | · | -15.8 | · | · | |
| Earnings Yield | -187.3% | -241.2% | · | -2355.8% | -1995.8% | -350.0% | · | -3.2% | -36.0% | -35.6% | · | -98.5% | -66.8% | -57.1% | · | -28.5% |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Net Income | $-40M | $3M | $-13M | $-18M | $-10M |
| Diluted EPS | $-22.61 | $2.63 | $-1.07 | $-2.41 | $-1.69 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Current Ratio | 0.9 | 8.5 | 1.5 | · | · |
| Quick Ratio | 0.6 | 6.0 | 1.4 | · | · |
No data for this statement
Not enough fundamentals data to build this statement yet.
Institutional owners (13F) 29 filers · $83.8M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
29
Value held
$83.8M
New positions
4
Exited positions
2
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 4 (-14 vs prior Q) | 2 (0 vs prior Q) | 6 (+3 vs prior Q) | 6 (+3 vs prior Q) | -1.0M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | $16,418,014 | 1,292,757 | 19.60% | Shares |
| Deep Track Capital, LP | $10,997,220 | 835,655 | 13.13% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $9,164,334 | 696,378 | 10.94% | Shares |
| Ally Bridge Group (NY) LLC | $8,163,398 | 620,319 | 9.75% | Shares |
| Trails Edge Capital Partners, LP | $7,331,475 | 557,103 | 8.75% | Shares |
| Woodline Partners LP | $5,815,548 | 441,911 | 6.94% | Shares |
| Yu Fan | $4,339,642 | 329,760 | 5.18% | Shares |
| SPHERA FUNDS MANAGEMENT LTD. | $4,284,784 | 325,591 | 5.12% | Shares |
| Squadron Capital Management LLC | $4,276,697 | 324,977 | 5.11% | Shares |
| Ikarian Capital, LLC | $2,697,801 | 205,000 | 3.22% | Shares |
| AMERIPRISE FINANCIAL INC | $2,443,812 | 185,700 | 2.92% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $2,161,859 | 164,275 | 2.58% | Shares |
| 683 Capital Management, LLC | $1,250,200 | 95,000 | 1.49% | Shares |
| ADAR1 Capital Management, LLC | $1,221,906 | 92,850 | 1.46% | Shares |
| GREAT POINT PARTNERS LLC | $1,133,734 | 86,150 | 1.35% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $816,946 | 62,078 | 0.98% | Shares |
| MILLENNIUM MANAGEMENT LLC | $737,552 | 56,045 | 0.88% | Shares |
| BANK OF MONTREAL /CAN/ | $149,642 | 11,371 | 0.18% | Shares |
| Seven Fleet Capital Management LP | $139,496 | 10,600 | 0.17% | Shares |
| MORGAN STANLEY | $99,476 | 7,559 | 0.12% | Shares |
| Allostery Investments LP | $76,303 | 155,720 | 0.09% | Shares |
| JNB Advisors LLC | $25,561 | 52,833 | 0.03% | Shares |
| UBS Group AG | $9,093 | 691 | 0.01% | Shares |
| OSAIC HOLDINGS, INC. | $4,737 | 360 | 0.01% | Shares |
| ROYAL BANK OF CANADA | $3,000 | 218 | 0.00% | Shares |
| Steward Partners Investment Advisory, LLC | $1,237 | 94 | 0.00% | Shares |
| Federation des caisses Desjardins du Quebec | $131 | 10 | 0.00% | Shares |
| TD Waterhouse Canada Inc. | $66 | 5 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $39 | 3 | 0.00% | Shares |
Activists & 5%+ owners 1 position
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| ABG Management Ltd., Ally Bridge Group (NY) LLC, Ally Bridge MedAlpha Master Fund L.P., ABG V-SIV IX Limited, Ally Bridge Group Global Life Science Capital Partners V, L.P., ABG Global Life Science Capital Partners V GP, L.P., ABG Global Life Science Capital Partners V GP Limited, ABG V-SIV X Limited, Fan Yu ×3 filings | Feb. 5, 2026 | 17.00% | Amendment | · | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 18 insiders · 7 officers · 10 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Neil K Warma | Chief Executive Officer | May 20, 2026 A | 6,183 | 0 | 0 | $0 |
| Gail M Farfel | Chief Executive Officer | Aug. 23, 2023 A | 55,192 | 0 | 0 | $0 |
| Daniel E. Geffken | Chief Financial Officer | Oct. 26, 2023 A | · | 0 | 0 | $0 |
| Gavin T. Malenfant | Chief Operating Officer | Oct. 26, 2023 A | 2,660 | 0 | 0 | $0 |
| Neil Cashman | Chief Scientific Officer | May 20, 2026 A | 4,122 | 0 | 0 | $0 |
| Max A. Milbury | Principal Accounting Officer | May 20, 2026 A | 8,409 | 1 | 0 | $14,892 |
| Larry Douglas Altstiel | Chief Medical Officer | Sept. 22, 2025 A | · | 0 | 0 | $0 |
| Slanix Paul Alex | Director | May 20, 2026 A | · | 0 | 0 | $0 |
| Eugene Williams | Director | May 20, 2026 A | 12,397 | 4 | 0 | $141,220 |
| Madge K. Shafmaster | Director | May 20, 2026 A | 208,333 | 0 | 0 | $0 |
| Josh Mandel-Brehm | Director | May 20, 2026 A | · | 0 | 0 | $0 |
| William W Wyman | Director | May 20, 2026 A | · | 0 | 0 | $0 |
| Patrick D. Kirwin | Director | April 22, 2026 P | 4,653 | 1 | 0 | $45,320 |
| Jeremy M. Sclar 2012 Irrevocable Family Trust | 10% owner | July 29, 2025 P | 3,710,459 | 0 | 0 | $0 |
| Jeremy M. Sclar | 10% owner | July 29, 2025 P | 3,710,459 | 0 | 0 | $0 |
| Johanne Kaplan | · | Aug. 5, 2026 P | 6,221 | 2 | 0 | $55,329 |
| Title 19 Promis | · | July 25, 2025 X | 2,435,029 | 0 | 0 | $0 |
| Michael S Gordon | · | July 25, 2025 X | 0 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
PMN Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 12 analysts
BUY
Median target
$34.11
+262.8%
2 16.7%
Strong Buy
9 75.0%
Buy
1 8.3%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
7 analysts · 2026-10-01Mean target $42.56 +352.8%
← Below all targets
Current price $9.40
Low$17.77
Mean$42.56
High$97.90
Peer comparison (GICS sub-industry) Key metrics vs sector peers
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Source: SEC 10-Q filed Aug 13, 2026