Ikarian Capital, LLC
CIK 1778253 · View on SEC EDGAR ↗
- Portfolio value
- $928.2M
- Positions
- 156
- As of
- June 30, 2026
#2,570 of 9,443 by 13F value · top 27.2%
Portfolio value QoQ: -24.6% 13F does not disclose cash
- Top 10 holdings weight
- 36.98%
- Top 25 holdings weight
- 60.51%
- Positions above 1%
- 29
- Effective number of positions
- 48.0
Based on 13F long-equity holdings only (cash, bonds, shorts not disclosed)
Turnover Q2 2026: 32.46% Est. buys $350,565,233 · sells $687,304,814
Median holding: 2.0 quarters Tracked Q4 2024–Q2 2026 · 35.1% still held
- New positions
- 41
- Increased
- 24
- Decreased
- 33
- Closed
- 31
Put-notional exposure: 20.1% puts 13F reports option positions at underlying notional value — may include hedges, not necessarily bearish bets
On this page
- Sector breakdown How the portfolio splits across market sectors.
- Portfolio Every stock this institution reports holding, from its latest 13F.
- High-conviction bets The holdings this manager is most concentrated in.
- Biggest new bets Brand-new positions opened in the latest quarter.
- Top moves The biggest position increases and decreases this quarter.
- Exited positions Positions the manager fully sold out of last quarter.
Sector breakdown
Healthcare
91.3%
Retail
0.0%
Other/Unmapped
8.7%
Full portfolio 156 positions
| Type | Streak | 8Q trend | |||||
|---|---|---|---|---|---|---|---|
| XBI XBI | $47,475,000 | 5.11% | 300,000 | Put option | $-54,709,000 | Down ×2 | |
| ABVX Abivax SA - American Depositary Shares | $45,454,986 | 4.90% | 341,100 | Call option | $12,796,031 | Up ×2 | |
| ABVX Abivax SA - American Depositary Shares | $43,352,978 | 4.67% | 328,635 | $37,120,286 | Up ×1 | ||
| KOD Kodiak Sciences Inc - Common Stock | $41,287,080 | 4.45% | 1,059,730 | $-6,965,026 | Down ×1 | ||
| ABVX Abivax SA - American Depositary Shares | $33,315,000 | 3.59% | 250,000 | Put option | Up ×1 | ||
| IONS Ionis Pharmaceuticals, Inc. - Common Stock | $31,716,000 | 3.42% | 400,000 | Call option | $23,298,411 | Up ×3 | |
| MRNA Moderna, Inc. - Common Stock | $28,012,000 | 3.02% | 400,000 | Put option | |||
| ALMS Alumis Inc. - Common Stock | $24,497,220 | 2.64% | 870,548 | $-2,237,242 | Down ×1 | ||
| PRAX Praxis Precision Medicines, Inc. - Common Stock | $24,386,773 | 2.63% | 72,842 | $1,324,091 | Up ×1 | ||
| IONS Ionis Pharmaceuticals, Inc. - Common Stock | $23,787,000 | 2.56% | 300,000 | Put option | Up ×1 | ||
| PCVX Vaxcyte, Inc. - Common Stock | $22,594,085 | 2.43% | 388,682 | $-2,316,626 | Down ×1 | ||
| ANIP ANI Pharmaceuticals, Inc. - Common Stock | $22,523,196 | 2.43% | 272,085 | $11,212,359 | Up ×1 | ||
| CLDX Celldex Therapeutics, Inc. - Common Stock | $17,804,985 | 1.92% | 478,500 | $3,174,230 | Up ×1 | ||
| RCUS Arcus Biosciences, Inc. Common Stock | $15,555,555 | 1.68% | 504,559 | ||||
| RLMD Relmada Therapeutics, Inc. - Common Stock | $14,866,644 | 1.60% | 2,148,359 | $-3,844,334 | Down ×2 | ||
| CAPR Capricor Therapeutics, Inc. - Common Stock | $14,549,497 | 1.57% | 604,215 | $-1,502,159 | Up ×1 | ||
| COGT Cogent Biosciences, Inc. - Common Stock | $14,322,251 | 1.54% | 370,084 | ||||
| Unknown issuer (CUSIP: N62509959) | $13,556,000 | 1.46% | 400,000 | Put option | Up ×1 | ||
| VERA Vera Therapeutics, Inc. - Class A Common Stock | $13,302,100 | 1.43% | 310,000 | $5,256,101 | Up ×1 | ||
| CTNM Contineum Therapeutics, Inc. - Common stock | $13,241,056 | 1.43% | 807,874 | $2,690,221 | |||
| TENX Tenax Therapeutics, Inc. - Common Stock | $11,459,580 | 1.23% | 787,600 | $-4,811,844 | Down ×1 | ||
| CCCC C4 Therapeutics, Inc. - Common Stock | $11,362,110 | 1.22% | 2,433,000 | Up ×1 | |||
| MAZE Maze Therapeutics, Inc. - Common Stock | $11,309,331 | 1.22% | 378,999 | $-3,789 | |||
| BHVN Biohaven Ltd. Common Shares | $11,132,933 | 1.20% | 748,181 | $7,643,344 | Up ×2 | ||
| CNTB Connect Biopharma Holdings Limited - Ordinary Shares | $10,801,710 | 1.16% | 4,538,534 | $-2,316,125 | Down ×1 | ||
| ANRO Alto Neuroscience, Inc. Common Stock | $10,749,651 | 1.16% | 407,338 | $-827,549 | Down ×1 | ||
| PHVS Pharvaris N.V. - Ordinary Shares | $10,680,241 | 1.15% | 308,856 | $-3,073,442 | Down ×1 | ||
| ALMS Alumis Inc. - Common Stock | $10,026,282 | 1.08% | 356,300 | Call option | $4,197,144 | Up ×1 | |
| JBIO Jade Biosciences, Inc. - Common Stock | $9,495,694 | 1.02% | 427,349 | $2,297,191 | Down ×1 | ||
| GLTO Galecto, Inc. - Common Stock | $8,731,816 | 0.94% | 335,710 | $36,927 | |||
| KOD Kodiak Sciences Inc - Common Stock | $8,481,592 | 0.91% | 217,700 | Call option | $4,669,592 | Up ×1 | |
| CAPR Capricor Therapeutics, Inc. - Common Stock | $8,428,000 | 0.91% | 350,000 | Call option | $-2,212,000 | ||
| ARWR Arrowhead Pharmaceuticals, Inc. - Common Stock | $8,151,000 | 0.88% | 100,000 | Put option | $4,545,750 | Up ×1 | |
| VRDN Viridian Therapeutics, Inc. - Common Stock | $7,807,251 | 0.84% | 425,000 | ||||
| PTHS | $7,251,459 | 0.78% | 256,598 | $1,860,335 | |||
| ZURA Zura Bio Limited - Class A Ordinary shares | $7,189,102 | 0.77% | 1,218,492 | $87,824 | Up ×2 | ||
| TECX Tectonic Therapeutic, Inc. - Common Stock | $7,075,647 | 0.76% | 205,837 | $2,206,178 | Up ×1 | ||
| PRAX Praxis Precision Medicines, Inc. - Common Stock | $6,695,800 | 0.72% | 20,000 | Call option | |||
| SPRB Spruce Biosciences, Inc. - Common Stock | $6,553,224 | 0.71% | 121,356 | $-1,377,390 | |||
| HIMS Hims & Hers Health, Inc. Class A Common Stock | $6,531,170 | 0.70% | 188,381 | Up ×1 | |||
| ELVN Enliven Therapeutics, Inc. - Common Stock | $6,421,957 | 0.69% | 126,541 | ||||
| PRQR ProQR Therapeutics N.V. - Ordinary Shares | $6,372,230 | 0.69% | 3,425,930 | $3,954,819 | Up ×1 | ||
| DRUG Bright Minds Biosciences Inc. - common stock | $6,244,361 | 0.67% | 88,951 | $-5,915,871 | Down ×1 | ||
| OVID Ovid Therapeutics Inc. - Common Stock | $6,105,503 | 0.66% | 2,269,704 | $-320,739 | Down ×1 | ||
| OCGN Ocugen, Inc. - Common Stock | $6,063,348 | 0.65% | 3,962,972 | $-1,109,631 | |||
| ACOG Alpha Cognition Inc. - Common Stock | $6,037,790 | 0.65% | 836,259 | $238,928 | Down ×1 | ||
| KYMR Kymera Therapeutics, Inc. - Common Stock | $5,779,368 | 0.62% | 50,400 | Put option | $1,581,552 | ||
| HROW Harrow, Inc. - Common Stock | $5,766,364 | 0.62% | 135,775 | $-13,381,473 | Down ×1 | ||
| KZIA Kazia Therapeutics Limited - American Depositary Shares | $5,578,510 | 0.60% | 396,201 | Up ×1 | |||
| RARE Ultragenyx Pharmaceutical Inc. - Common Stock | $5,529,952 | 0.60% | 165,617 | $-4,579,911 | Down ×1 | ||
| QTTB Q32 Bio Inc. - Common Stock | $5,478,200 | 0.59% | 430,000 | Up ×1 | |||
| TENX Tenax Therapeutics, Inc. - Common Stock | $5,428,605 | 0.58% | 373,100 | Call option | $3,600,948 | Up ×1 | |
| EPRX Eupraxia Pharmaceuticals Inc. - Common Stock | $5,352,388 | 0.58% | 809,741 | $-3,442,338 | Down ×1 | ||
| EYPT EyePoint, Inc. - Common Stock | $5,296,720 | 0.57% | 370,400 | Call option | $522,264 | ||
| EYPT EyePoint, Inc. - Common Stock | $5,296,720 | 0.57% | 370,400 | Put option | $522,264 | ||
| SLS SELLAS Life Sciences Group, Inc. - Common Stock | $5,235,372 | 0.56% | 354,700 | Put option | Up ×1 | ||
| BIOA BioAge Labs, Inc. - Common Stock | $4,901,999 | 0.53% | 200,000 | Up ×1 | |||
| RZLT Rezolute, Inc. - Common Stock (NV) | $4,862,062 | 0.52% | 935,012 | $4,811,801 | Up ×1 | ||
| OLMA Olema Pharmaceuticals, Inc. - Common Stock | $4,794,845 | 0.52% | 383,281 | $-4,125,525 | Down ×2 | ||
| SION Sionna Therapeutics, Inc. - Common Stock | $4,728,925 | 0.51% | 107,500 | Put option | Up ×1 | ||
| MNPR Monopar Therapeutics Inc. - Common Stock | $4,431,450 | 0.48% | 47,861 | ||||
| BBIO BridgeBio Pharma, Inc. - Common Stock | $4,276,418 | 0.46% | 57,417 | $-7,614,093 | Down ×1 | ||
| CLDX Celldex Therapeutics, Inc. - Common Stock | $4,241,940 | 0.46% | 114,000 | Put option | $625,860 | ||
| IVA Inventiva S.A. - American Depository Shares | $4,152,521 | 0.45% | 1,129,101 | $-3,690,260 | Down ×1 | ||
| ABSI Absci Corporation - Common Stock | $4,100,217 | 0.44% | 353,772 | Up ×1 | |||
| ALEC Alector, Inc. - Common Stock | $3,985,038 | 0.43% | 1,982,606 | $-492,565 | Down ×1 | ||
| CLYM Climb Bio, Inc. - Common Stock | $3,912,000 | 0.42% | 300,000 | ||||
| FULC Fulcrum Therapeutics, Inc. - Common Stock | $3,839,929 | 0.41% | 1,049,161 | $-4,207,136 | |||
| CRDL Cardiol Therapeutics Inc. - Class A Common Shares | $3,524,500 | 0.38% | 3,325,000 | $-154,250 | Up ×1 | ||
| Unknown issuer (CUSIP: 22978P205) | $3,293,728 | 0.35% | 104,364 | Up ×1 | |||
| CPIX Cumberland Pharmaceuticals Inc. - Common Stock | $3,260,431 | 0.35% | 503,153 | $1,462,683 | Down ×2 | ||
| ARWR Arrowhead Pharmaceuticals, Inc. - Common Stock | $3,120,040 | 0.34% | 38,278 | Up ×1 | |||
| VERA Vera Therapeutics, Inc. - Class A Common Stock | $3,076,647 | 0.33% | 71,700 | Call option | $192,156 | ||
| RNTX Rein Therapeutics, Inc. - Common Stock | $3,068,000 | 0.33% | 2,950,000 | Up ×1 | |||
| ARVN Arvinas, Inc. - Common Stock | $2,977,115 | 0.32% | 358,257 | $-820,409 | |||
| ABOS Acumen Pharmaceuticals, Inc. - Common Stock | $2,813,638 | 0.30% | 1,053,797 | $326,678 | |||
| PMN ProMIS Neurosciences Inc. - Common Shares | $2,697,801 | 0.29% | 205,000 | $1,999,301 | Up ×1 | ||
| QTTB Q32 Bio Inc. - Common Stock | $2,548,000 | 0.27% | 200,000 | Put option | Up ×1 | ||
| OLMA Olema Pharmaceuticals, Inc. - Common Stock | $2,502,000 | 0.27% | 200,000 | Call option | $-5,695,518 | Down ×1 | |
| ANNX Annexon, Inc. - common stock | $2,456,693 | 0.26% | 430,244 | $-757,858 | Down ×1 | ||
| BMY Bristol-Myers Squibb Company Common Stock | $2,448,850 | 0.26% | 42,500 | Put option | $-27,876,150 | Down ×1 | |
| LXEO Lexeo Therapeutics, Inc. - Common Stock | $2,388,066 | 0.26% | 513,011 | $-556,617 | |||
| DCTH Delcath Systems, Inc. - Common Stock | $2,337,548 | 0.25% | 185,667 | $-1,664,461 | Down ×1 | ||
| IVVD Invivyd, Inc. - Common Stock | $2,317,592 | 0.25% | 2,656,570 | $-1,135,950 | |||
| Unknown issuer (CUSIP: N90064901) | $2,293,788 | 0.25% | 49,800 | Call option | $-3,510,462 | Down ×1 | |
| CABA Cabaletta Bio, Inc. - Common Stock | $2,177,000 | 0.23% | 700,000 | $-244,000 | Down ×1 | ||
| NMRA Neumora Therapeutics, Inc. - Common Stock | $2,173,294 | 0.23% | 1,278,408 | $-319,602 | |||
| AMLX Amylyx Pharmaceuticals, Inc. - Common Stock | $2,110,301 | 0.23% | 117,500 | ||||
| TARS Tarsus Pharmaceuticals, Inc. - Common Stock | $1,961,588 | 0.21% | 31,166 | $-224,707 | |||
| SLN Silence Therapeutics Plc - American Depository Share | $1,827,725 | 0.20% | 830,784 | $96,157 | Down ×1 | ||
| DERM Journey Medical Corporation - Common Stock | $1,780,168 | 0.19% | 251,436 | $600,933 | |||
| DBVT DBV Technologies S.A. - American Depositary Shares | $1,690,953 | 0.18% | 525,000 | $-507,823 | |||
| IBIO iBio, Inc. - Common Stock | $1,674,859 | 0.18% | 957,062 | $-143,559 | |||
| AVTX Avalo Therapeutics, Inc. - Common Stock | $1,666,581 | 0.18% | 90,183 | ||||
| AVR Anteris Technologies Global Corp. - Common Stock | $1,640,724 | 0.18% | 166,571 | $-393,745 | Down ×1 | ||
| PALI Palisade Bio, Inc. - Common Stock | $1,567,500 | 0.17% | 750,000 | $1,086,288 | Up ×1 | ||
| Unknown issuer (CUSIP: G0375M101) | $1,524,000 | 0.16% | 150,000 | Up ×1 | |||
| KLRS Kalaris Therapeutics, Inc. - Common Stock | $1,465,201 | 0.16% | 360,000 | $-611,999 | |||
| Unknown issuer (CUSIP: 22053A305) | $1,314,245 | 0.14% | 72,251 | Up ×1 | |||
| LPCN Lipocine Inc. - Common Stock | $1,301,902 | 0.14% | 508,556 | $-2,761,460 | |||
| No matches | |||||||
Conviction holdings
Positions increased for 3+ consecutive quarters.
Share counts are as reported in 13F filings (not split-adjusted)
| Security | Value | % of portfolio | Streak |
|---|---|---|---|
| IONS | $31,716,000 | 3.42% | up ×3 |
Biggest new bets
New positions opened this quarter, largest first.
| Security | Value | Shares | % of portfolio |
|---|---|---|---|
| ABVX | $33,315,000 | 250,000 | 3.59% |
| MRNA | $28,012,000 | 400,000 | 3.02% |
| IONS | $23,787,000 | 300,000 | 2.56% |
| RCUS | $15,555,555 | 504,559 | 1.68% |
| COGT | $14,322,251 | 370,084 | 1.54% |
| Unknown issuer (CUSIP: N62509959) | $13,556,000 | 400,000 | 1.46% |
| CCCC | $11,362,110 | 2,433,000 | 1.22% |
| VRDN | $7,807,251 | 425,000 | 0.84% |
| PRAX | $6,695,800 | 20,000 | 0.72% |
| HIMS | $6,531,170 | 188,381 | 0.70% |
| ELVN | $6,421,957 | 126,541 | 0.69% |
| KZIA | $5,578,510 | 396,201 | 0.60% |
| QTTB | $5,478,200 | 430,000 | 0.59% |
| SLS | $5,235,372 | 354,700 | 0.56% |
| BIOA | $4,901,999 | 200,000 | 0.53% |
Top movers (QoQ)
| Security | Action | Shares Δ | Value Δ |
|---|---|---|---|
| XBI | Trimmed | -500K | -$54.7M |
| IONS | Bought more | +288K | +$23.3M |
| HROW | Trimmed | -407K | -$13.4M |
| ABVX | Bought more | +48K | +$12.8M |
| ANIP | Bought more | +125K | +$11.2M |
| BHVN | Bought more | +336K | +$7.6M |
| BBIO | Trimmed | -103K | -$7.6M |
| KOD | Trimmed | -206K | -$7.0M |
| DRUG | Trimmed | -78K | -$5.9M |
| OLMA | Trimmed | -350K | -$5.7M |
2 positions hidden (data completeness check)
Exited positions
Includes corporate events (mergers, delistings) — not all exits are sells
Closed positions reflect 13F reporting changes; for index managers these are often mechanical (delisting, M&A, index rebalancing), not active decisions.
| Security | Quarter | Shares before | Value before | Price since exit |
|---|---|---|---|---|
| SPY | June 30, 2025 | 345,000 | $192,989,550 | No longer tracked |
| TERN | June 30, 2026 | 2,656,378 | $140,044,248 | No longer tracked |
| XBI | March 31, 2025 | 1,450,000 | $130,587,000 | No longer tracked |
| CDTX | March 31, 2026 | 573,243 | $126,623,645 | No longer tracked |
| LLY | June 30, 2025 | 150,000 | $123,886,500 | 60.3% |
| UTHR | Dec. 31, 2025 | 212,100 | $88,914,441 | 8.0% |
| CYTK | June 30, 2026 | 1,242,472 | $81,891,330 | -9.1% |
| AMGN | March 31, 2026 | 245,000 | $80,190,951 | 23.9% |
| QQQ | June 30, 2026 | 100,000 | $57,718,000 | |
| GMAB | Dec. 31, 2025 | 175,000 | $53,021,552 | 8.9% |
| IWM | June 30, 2026 | 200,000 | $49,600,000 | No longer tracked |
| CORT | June 30, 2025 | 387,900 | $44,305,938 | 67.1% |
| TSN | March 31, 2025 | 630,000 | $36,187,200 | -9.5% |
| BMY | Dec. 31, 2025 | 800,000 | $36,080,000 | 22.5% |
| RAPT | March 31, 2026 | 955,271 | $32,355,028 | No longer tracked |
| BBIO | June 30, 2025 | 746,237 | $25,797,413 | 91.4% |
| OMER | March 31, 2026 | 1,500,000 | $25,762,504 | 77.6% |
| RVMD | June 30, 2026 | 258,142 | $25,104,311 | 13.4% |
| SRRK | Dec. 31, 2025 | 657,800 | $24,496,472 | 25.1% |
| CORT | March 31, 2026 | 586,093 | $20,396,036 | 204.2% |
| AMGN | March 31, 2025 | 74,000 | $19,287,360 | 40.0% |
| ALNY | Sept. 30, 2025 | 56,594 | $18,454,737 | -49.6% |
| CRNX | March 31, 2026 | 368,500 | $17,153,675 | 133.3% |
| NBIX | March 31, 2026 | 105,062 | $14,900,943 | 16.9% |
| NVO | June 30, 2026 | 400,000 | $14,700,000 | -2.5% |
| KPTI | June 30, 2026 | 2,573,435 | $14,334,033 | -81.1% |
| VRNA | Sept. 30, 2025 | 146,831 | $13,887,276 | No longer tracked |
| APGE | Sept. 30, 2025 | 319,547 | $13,877,927 | 239.3% |
| PPC | March 31, 2025 | 300,000 | $13,617,000 | -42.8% |
| DNTH | Dec. 31, 2025 | 346,001 | $13,615,140 | 171.3% |
| CTMX | March 31, 2026 | 3,172,616 | $13,515,344 | -28.1% |
| ORKA | June 30, 2026 | 242,021 | $11,871,130 | 12.4% |
| AKRO | Dec. 31, 2025 | 248,454 | $11,796,596 | No longer tracked |
| SLNO | June 30, 2026 | 344,123 | $11,521,238 | No longer tracked |
| ANAB | Dec. 31, 2025 | 370,610 | $11,348,078 | 18.5% |
| MLTX | Dec. 31, 2025 | 1,498,039 | $10,740,939 | 20.3% |
| CELC | March 31, 2026 | 105,545 | $10,527,058 | -19.2% |
| BPMC | June 30, 2025 | 113,904 | $10,081,644 | No longer tracked |
| APLS | March 31, 2026 | 397,347 | $9,981,357 | No longer tracked |
| PTGX | June 30, 2025 | 200,000 | $9,672,000 | 174.7% |
| DXCM | March 31, 2026 | 137,500 | $9,125,875 | 42.4% |
| PTCT | March 31, 2026 | 118,657 | $9,013,186 | 3.6% |
| MTSR | Dec. 31, 2025 | 172,000 | $9,000,760 | No longer tracked |
| TRUP | June 30, 2025 | 240,000 | $8,944,800 | -44.9% |
| RNA | June 30, 2025 | 300,000 | $8,856,000 | -53.8% |
| VTYX | March 31, 2026 | 958,704 | $8,657,097 | No longer tracked |
| AXSM | March 31, 2025 | 100,000 | $8,461,000 | 78.9% |
| BHVN | June 30, 2025 | 348,200 | $8,370,728 | 1.0% |
| NVO | Dec. 31, 2025 | 150,000 | $8,323,500 | -8.2% |
| CGON | March 31, 2026 | 199,473 | $8,282,119 | 15.6% |
| PVLA | June 30, 2026 | 64,626 | $8,055,631 | -5.2% |
| MBX | Dec. 31, 2025 | 448,071 | $7,841,243 | 110.3% |
| CALM | March 31, 2025 | 75,000 | $7,719,000 | -8.6% |
| CNTA | Dec. 31, 2025 | 307,700 | $7,461,725 | No longer tracked |
| ANAB | March 31, 2025 | 560,800 | $7,424,992 | 209.1% |
| ACLX | June 30, 2025 | 111,600 | $7,320,960 | No longer tracked |
| MLYS | March 31, 2026 | 200,000 | $7,257,999 | -4.1% |
| AGIO | March 31, 2026 | 252,689 | $6,878,195 | -0.1% |
| IMVT | June 30, 2025 | 400,000 | $6,836,000 | 178.4% |
| SYRE | March 31, 2025 | 282,159 | $6,568,661 | 576.7% |
| EWTX | June 30, 2025 | 280,000 | $6,160,000 | 234.8% |
| LLY | June 30, 2026 | 6,547 | $6,021,734 | 4.2% |
| ELVN | June 30, 2025 | 289,538 | $5,698,108 | 195.9% |
| SPRY | Dec. 31, 2025 | 562,400 | $5,652,120 | -52.1% |
| ONC | March 31, 2025 | 29,800 | $5,504,358 | 38.2% |
| VRDN | Dec. 31, 2025 | 245,518 | $5,298,278 | -20.9% |
| SNDX | Dec. 31, 2025 | 333,733 | $5,134,482 | -5.7% |
| SRZN | June 30, 2026 | 173,107 | $5,042,607 | -8.3% |
| LQDA | Dec. 31, 2025 | 200,000 | $4,548,000 | 103.0% |
| ARCT | Dec. 31, 2025 | 237,921 | $4,384,884 | 91.4% |
| LENZ | March 31, 2025 | 149,502 | $4,316,123 | -81.4% |
| ARGX | Dec. 31, 2025 | 5,942 | $4,303,146 | 23.2% |
| ADMA | March 31, 2026 | 234,854 | $4,283,737 | 8.9% |
| MRNA | March 31, 2025 | 100,000 | $4,158,000 | 404.8% |
| LEGN | June 30, 2026 | 226,888 | $4,104,404 | -24.6% |
| NUVL | March 31, 2025 | 52,216 | $4,087,469 | No longer tracked |
| PVLA | Dec. 31, 2025 | 64,746 | $4,058,926 | 38.4% |
| TEVA | Dec. 31, 2025 | 200,000 | $4,040,000 | 19.1% |
| VERA | Sept. 30, 2025 | 167,296 | $3,941,494 | 8.9% |
| ALT | Dec. 31, 2025 | 1,000,000 | $3,770,000 | -16.6% |
| INCY | June 30, 2025 | 60,400 | $3,657,220 | 87.3% |
| KRYS | March 31, 2026 | 14,814 | $3,652,243 | 32.0% |
| TRVI | June 30, 2025 | 575,000 | $3,616,749 | 234.8% |
| PRME | Dec. 31, 2025 | 650,000 | $3,601,000 | -4.8% |
| TGTX | March 31, 2026 | 117,903 | $3,514,689 | 66.1% |
| ZBIO | March 31, 2026 | 93,600 | $3,398,616 | 63.2% |
| TECX | Sept. 30, 2025 | 163,696 | $3,252,639 | 140.4% |
| AQST | March 31, 2026 | 500,000 | $3,230,000 | 11.2% |
| GOSS | March 31, 2026 | 1,000,000 | $3,100,000 | -53.3% |
| GALT | March 31, 2025 | 2,400,100 | $3,096,129 | 205.7% |
| NKTR | March 31, 2026 | 72,600 | $3,069,528 | 4.4% |
| UPB | Dec. 31, 2025 | 161,113 | $3,030,535 | -74.4% |
| KROS | June 30, 2025 | 274,009 | $2,792,152 | -18.1% |
| ERAS | March 31, 2026 | 735,396 | $2,735,673 | 9.0% |
| ELDN | Sept. 30, 2025 | 1,000,221 | $2,710,599 | 37.8% |
| BIIB | Sept. 30, 2025 | 21,516 | $2,702,195 | 53.9% |
| BBIO | Dec. 31, 2025 | 51,967 | $2,699,166 | 8.0% |
| PCSC | June 30, 2026 | 240,951 | $2,643,232 | No longer tracked |
| SRPT | Dec. 31, 2025 | 137,000 | $2,639,990 | -9.1% |
| VIR | June 30, 2026 | 293,258 | $2,627,591 | -7.7% |
| ALGS | March 31, 2025 | 64,300 | $2,561,712 | -19.8% |
| ABEO | June 30, 2025 | 533,581 | $2,539,846 | 7.6% |
| CMPX | June 30, 2025 | 1,324,400 | $2,516,360 | -7.1% |
| SANA | March 31, 2025 | 1,515,000 | $2,469,449 | 130.4% |
| ZVRA | March 31, 2025 | 292,772 | $2,441,719 | 58.5% |
| RLAY | Dec. 31, 2025 | 467,362 | $2,439,630 | 137.1% |
| XENE | March 31, 2025 | 62,052 | $2,432,438 | 79.4% |
| BBOT | June 30, 2026 | 270,231 | $2,418,568 | 22.0% |
| NUVL | June 30, 2026 | 23,594 | $2,417,206 | No longer tracked |
| NVAX | March 31, 2025 | 300,000 | $2,412,000 | 38.0% |
| JAZZ | June 30, 2026 | 12,460 | $2,355,563 | 3.9% |
| EOLS | June 30, 2025 | 193,265 | $2,324,979 | -9.9% |
| REPL | June 30, 2026 | 300,000 | $2,295,000 | 32.1% |
| GERN | Sept. 30, 2025 | 1,600,000 | $2,256,000 | 13.5% |
| SLRN | March 31, 2025 | 676,608 | $2,124,549 | No longer tracked |
| CRDF | March 31, 2025 | 450,000 | $1,953,000 | -71.0% |
| TARA | March 31, 2025 | 350,489 | $1,850,582 | -8.0% |
| LRMR | Dec. 31, 2025 | 548,400 | $1,771,332 | 8.7% |
| BMEA | March 31, 2025 | 431,100 | $1,672,668 | -35.7% |
| ACHL | March 31, 2025 | 1,441,141 | $1,642,901 | No longer tracked |
| VERV | June 30, 2025 | 358,393 | $1,637,857 | No longer tracked |
| NAMS | March 31, 2026 | 45,830 | $1,607,716 | -12.5% |
| HROW | June 30, 2025 | 58,300 | $1,550,780 | 36.7% |
| QURE | June 30, 2026 | 91,060 | $1,488,831 | 7.3% |
| RCKT | June 30, 2025 | 221,911 | $1,480,146 | 44.1% |
| DYN | Dec. 31, 2025 | 113,837 | $1,440,039 | 34.9% |
| TVTX | March 31, 2026 | 36,600 | $1,398,486 | 118.7% |
| CPRX | March 31, 2026 | 57,388 | $1,339,436 | No longer tracked |
| JANX | Dec. 31, 2025 | 54,691 | $1,336,648 | 27.4% |
| RCUS | Sept. 30, 2025 | 163,363 | $1,329,775 | 121.1% |
| ZYME | Dec. 31, 2025 | 72,787 | $1,243,202 | 2.7% |
| CRVS | June 30, 2025 | 388,100 | $1,234,158 | 264.4% |
| NUVB | Sept. 30, 2025 | 619,258 | $1,207,553 | 88.8% |
| TDOC | June 30, 2025 | 150,000 | $1,194,000 | -26.3% |
| DFTX | June 30, 2026 | 58,803 | $1,111,377 | -2.1% |
| MIST | March 31, 2025 | 466,030 | $1,099,830 | 30.1% |
| OKUR | June 30, 2025 | 253,754 | $1,091,143 | 66.1% |
| TRML | Sept. 30, 2025 | 67,927 | $1,086,152 | No longer tracked |
| NKTR | June 30, 2025 | 1,579,528 | $1,074,079 | 190.8% |
| IFRX | Dec. 31, 2025 | 722,066 | $967,568 | 103.0% |
| SLDB | June 30, 2025 | 230,000 | $851,001 | 93.4% |
| VERUXXXX | Sept. 30, 2025 | 1,425,239 | $829,204 | No longer tracked |
| MNMD | March 31, 2026 | 58,803 | $787,373 | No longer tracked |
| ORKA | Sept. 30, 2025 | 68,574 | $768,715 | 456.1% |
| CMPS | March 31, 2025 | 202,894 | $766,939 | 382.7% |
| AMLX | March 31, 2025 | 201,187 | $760,486 | 1047.6% |
| KZR | June 30, 2026 | 102,211 | $758,405 | No longer tracked |
| IMUX | June 30, 2026 | 674,662 | $748,876 | 7.4% |
| TVRD | Dec. 31, 2025 | 19,000 | $740,430 | -56.9% |
| IBB | Sept. 30, 2025 | 5,755 | $728,065 | 48.0% |
| ETNB | June 30, 2025 | 100,000 | $727,001 | No longer tracked |
| OLMA | June 30, 2025 | 191,994 | $721,897 | 162.4% |
| CNTA | June 30, 2026 | 18,113 | $719,448 | No longer tracked |
| KALV | June 30, 2026 | 35,119 | $706,946 | No longer tracked |
| CRBP | Dec. 31, 2025 | 54,800 | $693,220 | 23.1% |
| INSM | June 30, 2026 | 4,214 | $689,074 | 17.6% |
| CATX | March 31, 2025 | 215,500 | $687,444 | No longer tracked |
| SONN | Dec. 31, 2025 | 150,000 | $687,000 | No longer tracked |
| NRIX | March 31, 2025 | 34,985 | $659,116 | 127.9% |
| CLDX | June 30, 2025 | 35,600 | $646,140 | 99.5% |
| GLUE | June 30, 2025 | 136,575 | $633,709 | 230.7% |
| CHRO | June 30, 2025 | 440,849 | $626,004 | No longer tracked |
| PRTA | Sept. 30, 2025 | 100,000 | $607,000 | -5.8% |
| CRBP | March 31, 2025 | 51,431 | $606,885 | 88.7% |
| INBX | Sept. 30, 2025 | 42,122 | $601,081 | 198.4% |
| PYXS | June 30, 2025 | 613,253 | $600,927 | 186.8% |
| IRON | June 30, 2025 | 11,900 | $590,716 | 47.8% |
| CELC | June 30, 2025 | 54,800 | $554,028 | 590.4% |
| SWTX | June 30, 2025 | 12,519 | $552,464 | No longer tracked |
| MLYS | June 30, 2025 | 34,300 | $544,684 | 92.0% |
| LYELXXXX | June 30, 2025 | 876,037 | $471,307 | No longer tracked |
| ITOS | June 30, 2025 | 78,585 | $469,152 | No longer tracked |
| KYMR | Sept. 30, 2025 | 10,000 | $436,400 | 117.4% |
| TVTX | March 31, 2025 | 22,600 | $393,692 | 262.6% |
| THRD | June 30, 2025 | 100,000 | $347,001 | No longer tracked |
| GPCR | March 31, 2026 | 4,824 | $335,510 | 5.5% |
| DNA | June 30, 2025 | 58,300 | $332,310 | -38.5% |
| TYRA | June 30, 2025 | 35,000 | $325,500 | 175.6% |
| SGMO | June 30, 2026 | 1,218,671 | $300,890 | No longer tracked |
| VERU | June 30, 2026 | 133,517 | $295,073 | -16.1% |
| ATXI | March 31, 2025 | 140,000 | $280,000 | No longer tracked |
| KPTIXXXX | March 31, 2025 | 408,899 | $276,539 | No longer tracked |
| ALLK | June 30, 2025 | 1,171,950 | $266,736 | No longer tracked |
| VIGL | Sept. 30, 2025 | 31,360 | $249,311 | No longer tracked |
| ACRS | June 30, 2025 | 150,900 | $230,877 | 348.7% |
| MNPR | June 30, 2025 | 5,908 | $215,111 | 209.3% |
| CLYM | June 30, 2025 | 175,088 | $213,608 | 1283.8% |
| QNRX | March 31, 2025 | 275,000 | $178,942 | -36.0% |
| ELEV | June 30, 2025 | 690,050 | $178,792 | No longer tracked |
| COGT | Dec. 31, 2025 | 11,280 | $161,981 | 1.8% |
| RZLT | June 30, 2025 | 50,058 | $145,168 | 10.0% |
| AEON | March 31, 2025 | 257,563 | $139,085 | No longer tracked |
| LYRAXXXX | June 30, 2025 | 1,058,148 | $133,645 | No longer tracked |
| LRMR | June 30, 2025 | 58,526 | $125,830 | 43.3% |
| SGMT | Sept. 30, 2025 | 11,984 | $91,318 | 49.1% |
| TPST | March 31, 2025 | 105,285 | $87,860 | -89.0% |
| IOBT | June 30, 2026 | 1,386,565 | $81,391 | No longer tracked |
| STOK | March 31, 2025 | 6,798 | $74,982 | 377.7% |
| CADL | March 31, 2025 | 8,600 | $74,647 | 125.0% |
| TKNO | Sept. 30, 2025 | 14,008 | $68,779 | 15.8% |
| HOOK | Sept. 30, 2025 | 52,996 | $66,510 | No longer tracked |
| LYRA | March 31, 2026 | 21,161 | $65,176 | No longer tracked |
| SHPH | June 30, 2026 | 68,993 | $46,832 | 17.2% |
| SYBX | March 31, 2026 | 19,966 | $22,362 | No longer tracked |
| ANEB | March 31, 2026 | 17,736 | $17,913 | No longer tracked |
| BCLI | March 31, 2025 | 6,016 | $13,657 | No longer tracked |
| CTMX | March 31, 2025 | 8,924 | $9,192 | 431.4% |
| AMIX | June 30, 2026 | 18,688 | $7,290 | -12.8% |
| GLYC | March 31, 2025 | 6,501 | $1,619 | No longer tracked |
| FDMT | March 31, 2025 | 40 | $223 | 410.2% |