your badges 52W Range $1–$3 17% of range Analyst Rating BUY 16 analysts Price Target $8 +403% upside P/E -5.0 ROE -61.2% Net Profit Margin ·

PRQR Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

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Price $1.64
P/E -5.0
EPS $-0.40
ROE -61.2%
52W Range $1–$3

PRQR Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

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10-Year Performance Revenue, net income, margins and EPS trends

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EPS$-0.40
2019-12-31 → 2025-12-31
Free Cash Flow$-54M
2017-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend PRQR 5Y avg Peer Median Verdict
P/E -5.05Y avg ≈-6.3 ≈-6.3 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

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Avg Surprise -0.22%
Next Report Nov 04, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 5, 2026 $-0.08 $-0.12 31.2%
March 31, 2026 $-0.13 $-0.12 -6.6%
Dec. 31, 2025 $-0.08 $-0.10 18.8%
Sept. 30, 2025 $-0.10 $-0.10 4.8%
June 30, 2025 $-0.12 $-0.08 -43.5%
March 31, 2025 $-0.10 $-0.09 -6.0%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

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Income Statement 13
Metric Trend 2025202420232022202120202019201820172016
R&D Expense $45M$36M$25M$51M$42M$38M$46M$30M$31M$32M
SG&A Expense $15M$14M$16M$19M$17M$14M$13M$13M$11M$9M
Operating Income $-43M$-30M$-32M$-65M$-57M$-42M$-57M$-36M$-40M$-40M
Interest Expense $929.0K$1M$1M·$3M$2M····
Interest Income $2M$3M$3M$5M$2M$313.0K$1M···
Pretax Income $-42M$-28M$-28M$-64M$-61M$-46M$-57M$-37M$-44M$-39M
Income Tax $19.0K$-197.0K$-78.0K$96.0K$117.0K$124.0K$132.0K$1.0K$2.0K·
Net Income $-42M$-28M$-28M$-64M$-61M$-47M$-56M$-37M$-44M$-39M
EPS (Basic) $-0.40$-0.32$-0.35$-0.90$-0.95$-0.93$-1.38···
EPS (Diluted) $-0.40$-0.32$-0.35$-0.90$-0.95$-0.93$-1.38···
Shares (Basic) 105,334,35786,086,48681,011,43871,641,30564,182,49250,060,56541,037,24434,052,52025,374,80723,346,507
Shares (Diluted) 105,334,35786,086,48681,011,43871,641,305······
EBITDA $-43M$-30M$-32M$-65M$-57M·$-57M$-36M$-40M·
Balance Sheet 11
Metric Trend 2025202420232022202120202019201820172016
Cash & Equivalents $92M$149M$119M$95M$188M$76M$112M$106M$48M$59M
Receivables $7M$4M········
Current Assets $100M$154M$121M$154M$191M$80M$115M$108M$51M$62M
PP&E (Net) ···$16M$17M$19M$2M$2M$3M$3M
Intangibles ········$39.0K$90.0K
Total Assets $113M$168M$138M$171M$210M$99M$118M$110M$53M$66M
Accounts Payable $298.0K$16.0K$2M$392.0K$191.0K$221.0K$445.0K$135.0K$546.0K$328.0K
Current Liabilities $32M$39M$34M$21M$28M$10M$11M$8M$8M$7M
Total Liabilities $63M$79M$96M$105M$96M$42M$24M$18M$14M$12M
Retained Earnings $-468M$-427M$-401M$-379M$-318M$-258M$-212M$-155M$-119M$-76M
Stockholders' Equity $49M$89M$41M$67M$114M$57M$94M$93M$39M$53M
Cash Flow 6
Metric Trend 2025202420232022202120202019201820172016
Operating Cash Flow $-53M$-36M$22M$-69M$-26M$-47M$-44M$-28M$-35M$-34M
CapEx $1M$1M$1M$708.0K$484.0K$924.0K$580.0K$312.0K$121.0K$3M
Investing Cash Flow $-1M$-4M$4M$-702.0K$-425.0K$-924.0K$-580.0K$-312.0K$-121.0K$-3M
Financing Cash Flow $-2M$70M$-2M$-31M$137M$14M$50M$86M$27M$357.0K
Free Cash Flow $-54M$-38M$20M$-69M$-26M·$-45M$-29M$-35M·
Levered FCF $-55M$-39M$19M·$-30M·····
Profitability 3
Metric Trend 2025202420232022202120202019201820172016
ROA -30.0%-18.2%-18.2%-34.2%-40.0%·-49.6%-45.2%-73.6%·
ROE -61.2%-42.7%-51.8%-72.6%-72.1%·-60.3%-55.8%-94.3%·
ROIC -88.0%-34.2%-76.8%-99.0%-50.3%·-61.0%-39.1%-102.9%·
Liquidity & Solvency 3
Metric Trend 2025202420232022202120202019201820172016
Current Ratio 3.14.03.57.36.9·10.413.36.0·
Quick Ratio 3.13.83.54.56.8·10.212.95.7·
Interest Coverage -46.8-28.3-26.5·-16.8·····
Per Share 2
Metric Trend 2025202420232022202120202019201820172016
Cash Flow / Share $-0.50$-0.42········
EPS (TTM) $-0.40$-0.32$-0.35$-0.90$-0.95·$-1.38···
Valuation (TTM) 3
Metric Trend 2025202420232022202120202019201820172016
Net Income TTM $-42M$-28M$-28M$-64M$-61M·$-56M$-37M$-44M·
P/E -5.0-8.3-5.7-4.1-8.4·-7.2···
Earnings Yield -19.8%-12.1%-17.7%-24.3%-11.9%·-13.9%···

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

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Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Net Income $-42M $-28M $-28M $-64M $-61M
Diluted EPS $-0.40 $-0.32 $-0.35 $-0.90 $-0.95

Institutional owners (13F) 71 filers · $113.4M total · As of June 30, 2026

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Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 71
Value held $113.4M
New positions 12
Exited positions 10
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
12 (+2 vs prior Q) 10 (+5 vs prior Q) 25 (+12 vs prior Q) 11 (-6 vs prior Q) +25.7M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
ADAGE CAPITAL PARTNERS GP, L.L.C. $16,769,568 9,015,897 14.79% Shares
Aberdeen Group plc $16,614,463 8,932,507 14.65% Shares
Affinity Asset Advisors, LLC $10,311,721 5,543,936 9.10% Shares
Privium Fund Management B.V. $10,267,245 5,520,024 9.06% Shares
Ikarian Capital, LLC $6,372,230 3,425,930 5.62% Shares
Woodline Partners LP $6,095,486 3,277,143 5.38% Shares
HEIGHTS CAPITAL MANAGEMENT, INC $5,138,120 2,762,430 4.53% Shares
MORGAN STANLEY $3,287,020 1,767,215 2.90% Shares
SPHERA FUNDS MANAGEMENT LTD. $3,268,872 1,757,458 2.88% Shares
Kynam Capital Management, LP $2,913,350 1,566,317 2.57% Shares
DAFNA Capital Management LLC $2,846,471 1,530,361 2.51% Shares
Squadron Capital Management LLC $2,811,383 1,511,496 2.48% Shares
683 Capital Management, LLC $2,591,104 1,393,067 2.29% Shares
CITADEL ADVISORS LLC $2,202,824 1,184,314 1.94% Shares
PLATINUM INVESTMENT MANAGEMENT LTD $2,156,536 1,159,428 1.90% Shares
TWO SIGMA INVESTMENTS, LP $2,118,010 1,138,715 1.87% Shares
Eversept Partners, LP $1,901,413 1,022,265 1.68% Shares
BOOTHBAY FUND MANAGEMENT, LLC $1,764,649 948,736 1.56% Shares
DIADEMA PARTNERS LP $1,722,390 926,016 1.52% Shares
UBS Group AG $1,188,992 639,243 1.05% Shares
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $1,153,000 620,000 1.02% Shares
M28 Capital Management LP $1,115,615 599,793 0.98% Shares
RAYMOND JAMES FINANCIAL INC $1,062,196 571,073 0.94% Shares
Lynx1 Capital Management LP $969,828 521,413 0.86% Shares
TWO SIGMA ADVISERS, LP $913,848 452,400 0.81% Shares
JANE STREET GROUP, LLC $846,493 455,104 0.75% Shares
STEMPOINT CAPITAL LP $801,760 431,054 0.71% Shares
BNP PARIBAS FINANCIAL MARKETS $512,674 275,631 0.45% Shares
Monaco Asset Management SAM $454,746 244,487 0.40% Shares
Persistent Asset Partners Ltd $439,804 236,454 0.39% Shares
Palo Alto Investors LP $351,181 188,807 0.31% Shares
Burkehill Global Management, LP $327,812 176,243 0.29% Shares
MILLENNIUM MANAGEMENT LLC $299,467 161,004 0.26% Shares
DEUTSCHE BANK AG\ $202,297 108,762 0.18% Shares
OneDigital Investment Advisors LLC $158,100 85,000 0.14% Shares
Quadrature Capital Ltd $157,739 84,806 0.14% Shares
RFG Advisory, LLC $119,040 64,000 0.10% Shares
Cubist Systematic Strategies, LLC $111,167 52,191 0.10% Shares
BANK OF AMERICA CORP /DE/ $107,954 58,040 0.10% Shares
GEODE CAPITAL MANAGEMENT, LLC $107,874 57,997 0.10% Shares
Point72 Asset Management, L.P. $94,213 50,652 0.08% Shares
Keating Financial Advisory Services, Inc. $88,447 47,552 0.08% Shares
Velan Capital Investment Management LP $83,700 45,000 0.07% Shares
GUGGENHEIM CAPITAL LLC $74,314 39,954 0.07% Shares
Steward Partners Investment Advisory, LLC $65,548 35,241 0.06% Shares
Axiom Investment Management LLC $57,660 31,000 0.05% Shares
MOODY LYNN LIEBERSON & WALKER, LLC $46,500 25,000 0.04% Shares
Vanguard Personalized Indexing Management, LLC $41,097 22,095 0.04% Shares
Mariner, LLC $37,514 20,169 0.03% Shares
Verdad Advisers, LP $35,526 19,100 0.03% Shares

Show all 71 institutional owners →

Activists & 5%+ owners 1 position

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Van Herk Investments B.V., Van Herk Investments THI B.V., Van Herk Private Equity Investments B.V., Stichting Administratiekantoor Penulata, Van Herk Management Services B.V., Onroerend Goed Beheer- en Beleggingsmaatschappij A. van Herk B.V., A. van Herk Holding B.V., Stichting Administratiekantoor Abchrys, Adrianus van Herk ×8 filings July 29, 2026 10.90% Amendment Passive investment SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 3 insiders · 1 officers · 3 directors

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Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Daniel Anton De Boer Chief Executive Officer July 31, 2026 P 500,000 3 0 $853,500
Bart Filius Director July 17, 2026 P 300,000 2 0 $489,000
Gylvin Lykke Hinsch Director June 2, 2026 A · 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

PRQR Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

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rating · 16 analysts BUY
Median target $8.00 +389.3%
6 37.5% Strong Buy
9 56.2% Buy
1 6.2% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

9 analysts · 2026-09-27

Mean target $8.22 +402.9%

← Below all targets Current price $1.64
Low$3.00 Mean$8.22 High$12.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

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FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
PRQR · -5.0 · · -61.2% ·
NAMS · · · · · ·
QURE $1.49B -6.9 -40.6% -1236.0% -204.2% ·

My Metrics Your personal watchlist — selected rows from Full Fundamentals

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Source: SEC 20-F filed Mar 12, 2026