IONS Ionis Pharmaceuticals, Inc. - Common Stock
IONS Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
IONS Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
IONS Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
- Achat fort 8 25,8%
- Achat 17 54,8%
- Conserver 6 19,4%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
21 analystes · 2026-08-18Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-0.69 | $-1.09 | 0.40% |
| 31 mars 2026 | $-0.56 | $-0.93 | 0.37% |
| 31 décembre 2025 | $-1.41 | $-1.35 | -0.06% |
| 30 septembre 2025 | $-0.80 | $-1.26 | 0.46% |
| 30 juin 2025 | $0.70 | $-0.44 | 1.1% |
| 31 mars 2025 | $-0.93 | $-1.14 | 0.21% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| IONS | $12.92B | -33.2 | — | — | -68.1% | — |
| APGE | $5.16B | -17.9 | — | — | — | — |
| PTGX | $5.47B | -42.6 | -89.4% | -282.8% | -20.3% | — |
| KYMR | $6.33B | -21.1 | -16.7% | -794.0% | -24.4% | — |
| KRYS | $7.20B | 36.0 | 33.9% | 52.6% | 18.1% | — |
| SYRE | $2.56B | 10.1 | -62.0% | — | -26.5% | — |
| PCVX | $6.05B | -8.2 | — | — | -26.6% | — |
| IMVT | $5.07B | -9.0 | 229.2% | — | -73.7% | — |
| IBRX | $2.00B | -5.2 | 668.3% | -310.2% | 71.0% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 16
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | · | · | · | $508M | $347M | $284M | $214M | |
| Cost of Revenue | $16M | $11M | $9M | $14M | $11M | $12M | $4M | $2M | $0 | $0 | · | · | |
| R&D Expense | $916M | $902M | $900M | · | $638M | $531M | $462M | $412M | $372M | $340M | $320M | $239M | |
| SG&A Expense | $394M | $267M | $233M | $150M | $186M | $354M | $287M | $245M | $108M | $49M | $37M | $20M | |
| Operating Expenses | $1.33B | $1.18B | $1.14B | $998M | $841M | $901M | $757M | $661M | $483M | $393M | $359M | $262M | |
| Operating Income | $-382M | $-475M | $-354M | $-410M | $-30M | $-172M | $366M | $-61M | $31M | $-20M | $-76M | $-48M | |
| Interest Expense | $17M | $17M | $13M | $8M | $9M | $10M | $12M | $45M | $45M | $39M | $37M | $22M | |
| Other Non-op | $-15M | $1M | $14M | $-7M | $-10M | $-62.0K | $-686.0K | $-182.0K | $-4M | $0 | · | · | |
| Pretax Income | $-380M | $-460M | $-334M | $-258M | $-29M | $-135M | $339M | $-76M | $-17M | $-57M | $-88M | $-54M | |
| Income Tax | $2M | $-6M | $32M | $12M | $-551.0K | $345M | $52M | $-291M | $-6M | $3M | $372.0K | $-15M | |
| Net Income | $-381M | $-454M | $-366M | $-270M | $-29M | $-444M | $278M | $274M | $346.0K | $-60M | $-88M | $-39M | |
| EPS (Basic) | $-2.38 | $-3.04 | $-2.56 | $-1.90 | $-0.20 | $-3.18 | $2.00 | $2.09 | $0.15 | $-0.50 | $-0.74 | · | |
| EPS (Diluted) | $-2.38 | $-3.04 | $-2.56 | $-1.90 | $-0.20 | $-3.18 | $1.90 | $2.07 | $0.15 | $-0.50 | $-0.74 | · | |
| Shares (Basic) | 160,010,000 | 149,514,000 | 143,190,000 | 141,848,000 | 141,021,000 | 139,612,000 | 139,998,000 | 132,320,000 | 124,016,000 | 120,933,000 | 119,719,000 | · | |
| Shares (Diluted) | 160,010,000 | 149,514,000 | 143,190,000 | 141,848,000 | 141,021,000 | 139,612,000 | 153,164,000 | 134,056,000 | 126,098,000 | 120,933,000 | 119,719,000 | · | |
| EBITDA | $-382M | $-475M | $-354M | $-410M | $-30M | $-172M | $366M | $-61M | $25M | $-46M | $-76M | $-48M |
Bilan 24
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $372M | $242M | $399M | $276M | $869M | $398M | $683M | $279M | $130M | $85M | $129M | $143M | |
| Short-term Investments | $2.31B | $2.06B | $1.93B | $1.71B | $1.25B | · | · | · | · | · | · | · | |
| Inventory | $10M | $13M | $7M | $22M | $25M | $22M | $18M | $9M | $10M | · | · | · | |
| Other Current Assets | $237M | $218M | $205M | $168M | $143M | $140M | $140M | $102M | $73M | $17M | $15M | $16M | |
| Current Assets | $2.99B | $2.62B | $2.64B | $2.20B | $2.35B | $2.13B | $2.72B | $2.21B | $1.17B | $798M | $837M | $837M | |
| PP&E (Net) | $123M | $94M | $71M | $74M | $178M | $181M | $154M | $132M | $122M | $93M | $90M | $89M | |
| Accum. Depreciation | $109M | $106M | $97M | $88M | $103M | $87M | $74M | $61M | $88M | $80M | $73M | $66M | |
| Intangibles | · | · | · | · | $29M | $28M | $26M | $24M | $22M | $20M | · | · | |
| Other Non-current Assets | $172M | $127M | $105M | $75M | $71M | $50M | $28M | $13M | $10M | $1M | · | · | |
| Total Assets | $3.52B | $3.00B | $2.99B | $2.53B | $2.61B | $2.39B | $3.23B | $2.67B | $1.32B | $912M | $948M | $956M | |
| Accounts Payable | $28M | $43M | $26M | $18M | $12M | $17M | $16M | $29M | $25M | $21M | $28M | $18M | |
| Accrued Liabilities | $106M | $108M | $148M | $140M | $89M | $90M | $67M | $48M | $67M | $36M | $28M | $30M | |
| Current Liabilities | $782M | $309M | $448M | $312M | $241M | $599M | $273M | $280M | $244M | $134M | $149M | $115M | |
| Capital Leases | $262M | $162M | $171M | $179M | $19M | · | · | · | · | · | · | · | |
| Other Non-current Liabilities | $28M | $52M | $42M | $16M | $7M | · | · | · | · | · | · | · | |
| Total Liabilities | $3.03B | $2.42B | $2.60B | $1.96B | $1.84B | $1.65B | $1.55B | $1.48B | $957M | $813M | $747M | $698M | |
| Long-term Debt | $1.81B | $1.25B | $1.31B | $1.19B | · | · | · | · | · | · | · | · | |
| Total Debt | $1.76B | $1.20B | $1.24B | $1.18B | · | · | · | · | · | · | · | · | |
| Common Stock | $163.0K | $158.0K | $144.0K | $142.0K | $141.0K | $140.0K | $140.0K | $138.0K | $125.0K | $122.0K | $120.0K | $118.0K | |
| Retained Earnings | $-2.63B | $-2.25B | $-1.80B | $-1.43B | $-1.16B | $-1.13B | $-708M | $-967M | $-1.24B | $-1.18B | $-1.09B | $-1.01B | |
| AOCI | $-25M | $-31M | $-33M | $-57M | $-33M | $-21M | $-25M | $-32M | $-32M | $-30M | $-14M | $40M | |
| Stockholders' Equity | $489M | $588M | $387M | $573M | $772M | $743M | $1.47B | $1.05B | $281M | $100M | $201M | $258M | |
| Liabilities + Equity | $3.52B | $3.00B | $2.99B | $2.53B | $2.61B | $2.39B | $3.23B | $2.67B | $1.32B | $912M | $948M | $956M | |
| Shares Outstanding | 163,304,875 | 157,908,815 | 144,340,526 | 142,057,736 | 141,210,015 | 140,365,594 | 140,339,615 | 137,928,828 | 124,976,373 | 121,636,273 | 120,351,480 | 118,442,726 |
Flux de trésorerie 14
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $134M | $130M | $106M | $100M | $121M | $230M | $147M | $131M | $86M | $72M | $59M | $31M | |
| Deferred Tax | $0 | $0 | $0 | $0 | $0 | $342M | $904.0K | $-291M | $0 | $0 | $0 | $-11M | |
| Amort. of Intangibles | $2M | $2M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | · | · | |
| Operating Cash Flow | $-269M | $-501M | $-308M | $-274M | $31M | $36M | $346M | $603M | $174M | $-112M | $21M | $6M | |
| CapEx | $51M | $45M | $24M | $16M | $12M | $35M | $31M | $14M | $35M | $7M | $8M | $8M | |
| Investing Cash Flow | $-278M | $-134M | $-214M | $-263M | $195M | $274M | $-41M | $-930M | $-358M | $57M | $-60M | · | |
| Stock Issued | $0 | $489M | $0 | $0 | · | $0 | $0 | $448M | $72M | $0 | $0 | $0 | |
| Stock Repurchased | · | · | · | $0 | $0 | $91M | $34M | $0 | $0 | · | · | · | |
| Net Stock Activity | $0 | $489M | · | $0 | $0 | $-91M | $-34M | · | $72M | · | $0 | $0 | |
| Financing Cash Flow | $676M | $478M | $644M | $-55M | $246M | $-597M | $100M | $476M | $229M | $11M | $25M | · | |
| Net Change in Cash | $130M | $-157M | $123M | $-593M | $472M | $-286M | $404M | $149M | $45M | $-44M | $-14M | · | |
| Taxes Paid | $-639.0K | $-6M | $48M | $5M | · | $26M | $9M | $0 | $0 | · | · | · | |
| Free Cash Flow | $-320M | $-546M | $-331M | $-290M | $19M | $772.0K | $315M | $589M | $139M | $-119M | $13M | $-1M | |
| Levered FCF | $-337M | $-563M | $-345M | $-299M | $10M | $-128M | $272M | $716M | $106M | $-159M | $-23M | $-17M |
Rentabilité 7
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | · | 4.8% | -13.4% | -26.7% | -22.3% | |
| Net Margin | · | · | · | · | · | · | · | · | -1.2% | -25.0% | -31.1% | -18.2% | |
| Pretax Margin | · | · | · | · | · | · | · | · | -4.6% | -24.1% | -31.0% | -25.4% | |
| EBITDA Margin | · | · | · | · | · | · | · | · | 4.8% | -13.4% | -26.7% | -22.3% | |
| ROA | -11.7% | -15.2% | -13.3% | -10.5% | -1.1% | -16.1% | 10.0% | 13.7% | -0.53% | -9.3% | -9.2% | -4.3% | |
| ROE | -68.1% | -71.9% | -104.3% | -40.1% | -3.8% | -39.0% | 23.4% | 41.2% | -2.8% | -57.6% | -38.5% | -12.3% | |
| ROIC | -17.1% | -26.0% | -23.8% | -24.5% | -3.8% | -58.4% | 21.8% | 16.5% | 5.5% | -48.1% | -37.9% | -13.3% |
Liquidité et Solvabilité 5
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.8 | 8.5 | 5.9 | 7.1 | 9.7 | 3.7 | 10.0 | 7.9 | 5.2 | 6.0 | 5.6 | 7.3 | |
| Quick Ratio | 3.4 | 7.4 | 5.2 | 6.4 | 3.6 | 0.7 | 2.5 | 1.0 | 0.6 | 0.6 | 0.9 | 1.2 | |
| Debt / Equity | 3.6 | 2.0 | 3.2 | 2.1 | · | · | · | · | · | · | · | · | |
| LT Debt / Equity | 2.7 | 2.0 | 3.2 | 2.1 | · | · | · | · | · | · | · | · | |
| Interest Coverage | -22.1 | -28.0 | -27.9 | -50.5 | -3.2 | -3.8 | 7.5 | -1.4 | 0.5 | -1.2 | -2.1 | -2.1 |
Efficacité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | · | · | · | 0.5 | 0.4 | 0.3 | 0.2 | |
| Inventory Turnover | 1.4 | 1.1 | 0.4 | 0.6 | 0.5 | 0.6 | 0.3 | 0.2 | · | · | · | · |
Valorisation (TTM) 14
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $944M | $705M | $788M | $587M | $810M | $729M | $1.12B | $600M | $508M | $347M | $284M | $214M | |
| Net Income TTM | $-381M | $-454M | $-366M | $-270M | $-29M | $-444M | $278M | $274M | $346.0K | $-60M | $-88M | $-39M | |
| Market Cap | $12.92B | $5.52B | $7.30B | $5.37B | $4.30B | $7.94B | $8.48B | $7.46B | $6.29B | $5.82B | $7.45B | $7.31B | |
| Enterprise Value | $12.00B | $4.43B | $6.21B | $4.55B | · | · | · | · | · | · | · | · | |
| P/E | -33.2 | -11.5 | -19.8 | -19.9 | -152.2 | -17.8 | 31.8 | 26.1 | 335.3 | -95.7 | -83.7 | -176.4 | |
| P/S | 13.7 | 7.8 | 9.3 | 9.1 | 5.3 | 10.9 | 7.6 | 12.4 | 12.4 | 16.8 | 26.3 | 34.1 | |
| P/B | 26.4 | 9.2 | 18.9 | 9.4 | 5.6 | 9.4 | 5.8 | 7.1 | 19.0 | 58.4 | 37.1 | 28.4 | |
| P / Tangible Book | 26.4 | 9.4 | 18.9 | 9.4 | 5.8 | 11.1 | · | · | · | · | · | · | |
| P / Cash Flow | -48.1 | -11.0 | -23.7 | -19.6 | 139.5 | 221.1 | 24.5 | 12.4 | 36.1 | -51.9 | 352.8 | 1163.5 | |
| P / FCF | -40.4 | -10.1 | -22.0 | -18.5 | 228.0 | 10280.1 | 26.9 | 12.7 | 45.1 | -48.8 | 554.9 | -5930.8 | |
| EV / EBITDA | -31.4 | -9.3 | -17.6 | -11.1 | · | · | · | · | · | · | · | · | |
| EV / FCF | -37.5 | -8.1 | -18.7 | -15.7 | · | · | · | · | · | · | · | · | |
| EV / Revenue | 12.7 | 6.3 | 7.9 | 7.8 | · | · | · | · | · | · | · | · | |
| Earnings Yield | -3.0% | -8.7% | -5.1% | -5.0% | -0.66% | -5.6% | 3.1% | 3.8% | 0.30% | -1.1% | -1.2% | -0.57% |
Compte de résultat 15
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $268M | $246M | $203M | $157M | $452M | $132M | $227M | $134M | $225M | $119M | $325M | $144M | $188M | $131M | $152M | $160M | |
| Cost of Revenue | $3M | $3M | $8M | $2M | $4M | $1M | $4M | $1M | $4M | $2M | $3M | $2M | $3M | $1M | $4M | $2M | |
| SG&A Expense | $150M | $150M | $130M | $97M | $91M | $76M | $88M | $62M | $65M | $53M | $71M | $70M | $46M | $46M | $48M | $34M | |
| Operating Expenses | $370M | $364M | $418M | $317M | $312M | $278M | $337M | $282M | $291M | $269M | $331M | $287M | $279M | $245M | $360M | $219M | |
| Operating Income | $-102M | $-117M | $-214M | $-160M | $140M | $-147M | $-111M | $-149M | $-66M | $-150M | $-6M | $-143M | $-90M | $-114M | $-208M | $-59M | |
| Interest Expense | $5M | $5M | $5M | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $5M | $4M | $2M | $2M | $2M | $2M | |
| Other Non-op | $987.0K | $-456.0K | $-16M | $363.0K | $102.0K | $465.0K | $302.0K | $142.0K | $610.0K | $277.0K | $235.0K | $2M | $11M | $230.0K | $123.0K | $5M | |
| Pretax Income | $-113M | $-92M | $-228M | $-128M | $124M | $-147M | $-107M | $-144M | $-66M | $-143M | $-3M | $-141M | $-77M | $-113M | $-44M | $-47M | |
| Income Tax | $1M | $218.0K | $1M | $213.0K | $-20.0K | $116.0K | $-3M | $-4M | $64.0K | $75.0K | $6M | $7M | $8M | $11M | $8M | $283.0K | |
| Net Income | $-115M | $-93M | $-229M | $-129M | $124M | $-147M | $-104M | $-140M | $-66M | $-143M | $-9M | $-147M | $-85M | $-124M | $-52M | $-47M | |
| EPS (Basic) | $-0.69 | $-0.56 | $-1.41 | $-0.80 | $0.78 | $-0.93 | $-0.66 | $-0.95 | $-0.45 | $-0.98 | $-0.06 | $-1.03 | $-0.60 | $-0.87 | $-0.37 | $-0.33 | |
| EPS (Diluted) | $-0.69 | $-0.56 | $-1.41 | $-0.80 | $0.70 | $-0.93 | $-0.66 | $-0.95 | $-0.45 | $-0.98 | $-0.06 | $-1.03 | $-0.60 | $-0.87 | $-0.37 | $-0.33 | |
| Shares (Basic) | 165,419,000 | 164,874,000 | -317,627,000 | 159,765,000 | 159,137,000 | 158,735,000 | -290,575,000 | 148,593,000 | 145,958,000 | 145,538,000 | -285,960,000 | 143,317,000 | 143,098,000 | 142,735,000 | -283,495,000 | 141,950,000 | |
| Shares (Diluted) | 165,419,000 | 164,874,000 | -340,821,000 | 159,765,000 | 182,331,000 | 158,735,000 | -290,575,000 | 148,593,000 | 145,958,000 | 145,538,000 | -285,960,000 | 143,317,000 | 143,098,000 | 142,735,000 | -283,495,000 | 141,950,000 | |
| EBITDA | $-102M | $-117M | · | $-160M | $140M | $-147M | · | $-149M | $-66M | $-150M | · | $-143M | $-90M | $-114M | · | $-59M |
Bilan 23
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $350M | $173M | $372M | $338M | $297M | $264M | $242M | $335M | $294M | $349M | · | $352M | $425M | $309M | · | $315M | |
| Short-term Investments | $1.70B | $1.75B | $2.31B | $1.90B | $1.99B | $1.88B | $2.06B | $2.15B | $1.78B | $1.86B | · | $1.88B | $1.96B | $2.04B | · | $1.67B | |
| Inventory | $51M | $6M | $10M | $10M | $8M | $12M | $13M | $28M | $29M | $30M | · | $26M | $26M | $22M | · | $21M | |
| Other Current Assets | $327M | $306M | $237M | $244M | $226M | $223M | $218M | $184M | $195M | $174M | · | $181M | $178M | $160M | · | $143M | |
| Current Assets | $2.49B | $2.94B | $2.99B | $2.52B | $2.58B | $2.42B | $2.62B | $2.71B | $2.33B | $2.42B | · | $2.58B | $2.62B | $2.54B | · | $2.15B | |
| PP&E (Net) | $155M | $142M | $123M | $106M | $112M | $103M | $94M | $83M | $76M | $73M | · | $71M | $92M | $85M | · | $181M | |
| Accum. Depreciation | · | · | $109M | · | · | · | $106M | · | · | · | · | · | · | · | · | · | |
| Intangibles | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $30M | |
| Other Non-current Assets | $117M | $136M | $172M | $166M | $132M | $132M | $127M | $120M | $119M | $106M | · | $104M | $86M | $78M | · | $59M | |
| Total Assets | $2.99B | $3.45B | $3.52B | $3.03B | $2.99B | $2.81B | $3.00B | $3.08B | $2.69B | $2.76B | · | $2.93B | $2.97B | $2.89B | · | $2.42B | |
| Accounts Payable | $48M | $26M | $28M | $14M | $23M | $17M | $43M | $9M | $9M | $13M | · | $6M | $24M | $10M | · | $21M | |
| Accrued Liabilities | $116M | $127M | $106M | $99M | $99M | $103M | $108M | $124M | $114M | $106M | · | $119M | $105M | $113M | · | $128M | |
| Current Liabilities | $316M | $717M | $782M | $903M | $897M | $250M | $309M | $305M | $306M | $328M | · | $404M | $288M | $259M | · | $283M | |
| Capital Leases | $262M | $259M | $262M | $263M | $164M | $159M | $162M | $168M | $166M | $169M | · | $173M | $175M | $177M | · | · | |
| Other Non-current Liabilities | $28M | $28M | · | $29M | $59M | $56M | · | $42M | $42M | $42M | · | $49M | $16M | $7M | · | · | |
| Total Liabilities | $2.55B | $2.96B | $3.03B | $2.42B | $2.35B | $2.34B | $2.42B | $2.42B | $2.43B | $2.47B | · | $2.62B | $2.54B | $2.40B | · | $1.83B | |
| Long-term Debt | · | · | $1.81B | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Common Stock | $166.0K | $166.0K | $163.0K | $161.0K | $159.0K | $159.0K | $158.0K | $158.0K | $146.0K | $146.0K | · | $143.0K | $143.0K | $143.0K | · | $142.0K | |
| Retained Earnings | $-2.84B | $-2.72B | $-2.63B | $-2.40B | $-2.27B | $-2.40B | $-2.25B | $-2.15B | $-2.00B | $-1.94B | · | $-1.79B | $-1.64B | $-1.55B | · | $-1.38B | |
| AOCI | $-34M | $-31M | $-25M | $-26M | $-28M | $-29M | $-31M | $-24M | $-35M | $-35M | · | $-46M | $-51M | $-49M | · | $-63M | |
| Stockholders' Equity | $440M | $491M | $489M | $618M | $632M | $476M | $588M | $662M | $264M | $297M | $387M | $315M | $428M | $487M | $573M | $594M | |
| Liabilities + Equity | $2.99B | $3.45B | $3.52B | $3.03B | $2.99B | $2.81B | $3.00B | $3.08B | $2.69B | $2.76B | · | $2.93B | $2.97B | $2.89B | · | $2.42B | |
| Shares Outstanding | 165,636,792 | 165,902,064 | 163,304,875 | 161,137,930 | 159,196,782 | 159,041,259 | 157,908,815 | 157,813,136 | 146,025,246 | 145,844,719 | · | 143,393,493 | 143,167,414 | 143,022,539 | · | 142,017,411 |
Flux de trésorerie 11
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $46M | $43M | $43M | $31M | $30M | $30M | $36M | $32M | $31M | $31M | $26M | $26M | $27M | $27M | $26M | $24M | |
| Amort. of Intangibles | $700.0K | $661.0K | $638.0K | $621.0K | $598.0K | $582.0K | $459.0K | $617.0K | $621.0K | $639.0K | $655.0K | $660.0K | $637.0K | $607.0K | $610.0K | $608.0K | |
| Operating Cash Flow | $566M | $-793M | $-138M | $-131M | $151M | $-151M | $-116M | $-115M | $-120M | $-150M | $33M | $-109M | $-97M | $-134M | $-200M | $-24M | |
| CapEx | $16M | $22M | $21M | $5M | $12M | $13M | $25M | $9M | $6M | $4M | $-819.0K | $2M | $12M | $10M | $4M | $6M | |
| Investing Cash Flow | $23M | $537M | $-420M | $91M | $-120M | $170M | $68M | $-341M | $62M | $76M | $-27M | $69M | $70M | $-326M | $212M | $-184M | |
| Stock Issued | · | · | $0 | · | · | · | $27.0K | · | · | · | $0 | · | · | · | · | · | |
| Financing Cash Flow | $-412M | $57M | $591M | $81M | $1M | $2M | $-44M | $496M | $3M | $24M | $41M | $-32M | $144M | $492M | $-51M | $2M | |
| Net Change in Cash | $177M | $-199M | $34M | $41M | $33M | $22M | $-93M | $41M | $-55M | $-50M | $47M | $-73M | $116M | $33M | $-39M | $-207M | |
| Taxes Paid | $1M | $-8.0K | $22.0K | $-278.0K | $17.0K | $-400.0K | $-8M | $80.0K | $2M | $13.0K | · | · | · | · | · | · | |
| Free Cash Flow | · | $-815M | · | · | · | $-163M | · | · | · | $-154M | · | · | · | $-144M | · | · | |
| Levered FCF | · | $-820M | · | · | · | $-167M | · | · | · | $-159M | · | · | · | $-146M | · | · |
Rentabilité 7
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -38.2% | -47.7% | · | -102.2% | 30.9% | -111.6% | · | -111.1% | -29.3% | -125.1% | · | -99.4% | -47.9% | -87.5% | · | -37.0% | |
| Net Margin | -42.8% | -37.6% | · | -82.1% | 27.3% | -111.6% | · | -105.0% | -29.4% | -119.5% | · | -102.2% | -45.3% | -95.2% | · | -29.4% | |
| Pretax Margin | -42.3% | -37.5% | · | -81.9% | 27.3% | -111.6% | · | -107.7% | -29.4% | -119.4% | · | -97.6% | -41.1% | -86.5% | · | -29.2% | |
| EBITDA Margin | -38.2% | -47.7% | · | -102.2% | 30.9% | -111.6% | · | -111.1% | -29.3% | -125.1% | · | -99.4% | -47.9% | -87.5% | · | -37.0% | |
| ROA | -3.8% | -2.9% | · | -4.2% | 4.3% | -5.3% | · | -4.7% | -2.3% | -5.1% | · | -5.5% | -3.1% | -4.6% | · | -1.9% | |
| ROE | -21.4% | -19.1% | · | -20.1% | 27.6% | -38.0% | · | -28.7% | -19.1% | -36.5% | · | -32.4% | -16.2% | -20.8% | · | -8.3% | |
| ROIC | -23.5% | -23.9% | · | -26.0% | 22.1% | -30.9% | · | -21.9% | -25.1% | -50.4% | · | -47.5% | -23.2% | -25.8% | · | -10.0% |
Liquidité et Solvabilité 3
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 7.9 | 4.1 | · | 2.8 | 2.9 | 9.7 | · | 8.9 | 7.6 | 7.4 | · | 6.4 | 9.1 | 9.8 | · | 7.6 | |
| Quick Ratio | 6.5 | 2.7 | · | 2.5 | 2.6 | 8.6 | · | 8.2 | 6.8 | 6.7 | · | 5.5 | 8.3 | 9.1 | · | 7.0 | |
| Interest Coverage | -22.2 | -22.8 | · | -38.0 | 34.0 | -35.7 | · | -35.7 | -14.7 | -36.0 | · | -34.1 | -39.4 | -71.0 | · | -27.7 |
Efficacité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.1 | 0.1 | · | 0.1 | 0.2 | 0.0 | · | 0.0 | 0.1 | 0.0 | · | 0.1 | 0.1 | 0.0 | · | 0.1 | |
| Inventory Turnover | 0.1 | 0.3 | · | 0.1 | 0.2 | 0.1 | · | 0.0 | 0.2 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 |
Valorisation (TTM) 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $874M | $1.06B | · | $967M | $944M | $717M | · | $803M | $813M | $777M | · | $615M | $631M | $576M | · | $875M | |
| Net Income TTM | $-565M | $-327M | · | $-256M | $-268M | $-458M | · | $-359M | $-366M | $-385M | · | $-409M | $-309M | $-329M | · | $7M | |
| Market Cap | $13.13B | $12.46B | · | $10.54B | $6.29B | $4.80B | · | $6.32B | $6.96B | $6.32B | · | $6.50B | $5.87B | $5.11B | · | $6.28B | |
| P/E | -22.9 | -36.3 | · | -38.7 | -21.5 | -10.1 | · | -16.4 | -18.9 | -16.2 | · | -15.8 | -18.9 | -15.5 | · | -368.6 | |
| P/S | 15.0 | 11.8 | · | 10.9 | 6.7 | 6.7 | · | 7.9 | 8.6 | 8.1 | · | 10.6 | 9.3 | 8.9 | · | 7.2 | |
| P/B | 29.9 | 25.4 | · | 17.1 | 10.0 | 10.1 | · | 9.5 | 26.4 | 21.3 | · | 20.6 | 13.7 | 10.5 | · | 10.6 | |
| P / Tangible Book | 29.9 | 25.4 | · | 17.1 | 10.0 | 10.1 | · | 9.5 | 26.4 | 21.3 | · | 20.6 | 13.7 | 10.5 | · | 11.1 | |
| P / Cash Flow | · | -15.7 | · | · | · | -31.8 | · | · | · | -42.2 | · | · | · | -38.1 | · | · | |
| P / FCF | · | -15.3 | · | · | · | -29.4 | · | · | · | -40.9 | · | · | · | -35.4 | · | · | |
| Earnings Yield | -4.4% | -2.8% | · | -2.6% | -4.7% | -9.9% | · | -6.1% | -5.3% | -6.2% | · | -6.3% | -5.3% | -6.5% | · | -0.27% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Résultat net | $-381M | $-454M | $-366M | $-270M | $-29M |
| BPA dilué | $-2.38 | $-3.04 | $-2.56 | $-1.90 | $-0.20 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Dette / Capitaux propres | 3.6 | 2.0 | 3.2 | 2.1 | — |
| Ratio de liquidité | 3.8 | 8.5 | 5.9 | 7.1 | 9.7 |
| Ratio de liquidité réduite | 3.4 | 7.4 | 5.2 | 6.4 | 3.6 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-320M | $-546M | $-331M | $-290M | $19M |
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Détenteurs institutionnels (13F) 575 déclarants · $10.8B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 80 (-4 vs T. préc.) | 40 (-25 vs T. préc.) | 199 (+17 vs T. préc.) | 156 (+3 vs T. préc.) | +28.2M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| Capital World Investors | $1 718 152 930 | 21 669 226 | 15,90% | Actions |
| FMR LLC | $1 062 239 646 | 13 396 893 | 9,83% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $623 182 054 | 7 859 529 | 5,77% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $571 799 597 | 7 211 497 | 5,29% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $558 240 214 | 7 040 487 | 5,17% | Actions |
| TWO SIGMA INVESTMENTS, LP | $495 748 197 | 6 252 342 | 4,59% | Actions |
| STATE STREET CORP | $343 710 098 | 4 334 848 | 3,18% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $260 920 005 | 3 157 327 | 2,41% | Actions |
| TWO SIGMA ADVISERS, LP | $241 452 501 | 3 052 111 | 2,23% | Actions |
| Artisan Partners Limited Partnership | $209 327 536 | 2 640 024 | 1,94% | Actions |
| Tweedy, Browne Co LLC | $180 805 859 | 2 280 311 | 1,67% | Actions |
| Deep Track Capital, LP | $174 438 000 | 2 200 000 | 1,61% | Actions |
| BAKER BROS. ADVISORS LP | $162 364 274 | 2 047 727 | 1,50% | Actions |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $156 967 955 | 1 979 669 | 1,45% | Actions |
| AMERICAN CENTURY COMPANIES INC | $154 383 816 | 1 947 076 | 1,43% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $127 260 529 | 1 605 001 | 1,18% | Actions |
| Pictet Asset Management Holding SA | $126 981 913 | 1 596 998 | 1,18% | Actions |
| BARCLAYS PLC | $125 150 305 | 1 578 387 | 1,16% | Actions |
| GOLDMAN SACHS GROUP INC | $117 215 755 | 1 478 317 | 1,08% | Actions |
| Polar Capital Holdings Plc | $115 289 325 | 1 454 021 | 1,07% | Actions |
| Alyeska Investment Group, L.P. | $112 426 560 | 1 417 916 | 1,04% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $103 108 716 | 1 300 400 | 0,95% | Option d'achat |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $103 108 000 | 1 300 392 | 0,95% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $84 114 400 | 1 060 845 | 0,78% | Actions |
| GROUPAMA ASSET MANAGMENT | $75 195 315 | 937 083 | 0,70% | Actions |
| Capital International Investors | $65 316 248 | 823 764 | 0,60% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $65 184 309 | 822 100 | 0,60% | Option de vente |
| Davern Capital Partners, LP | $63 329 637 | 798 709 | 0,59% | Actions |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | $62 422 083 | 787 263 | 0,58% | Actions |
| Connor, Clark & Lunn Investment Management Ltd. | $54 253 072 | 684 236 | 0,50% | Actions |
| Eversept Partners, LP | $52 702 794 | 664 684 | 0,49% | Actions |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $51 970 948 | 655 454 | 0,48% | Actions |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $51 370 722 | 647 884 | 0,48% | Actions |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $50 113 500 | 632 028 | 0,46% | Actions |
| Caption Management, LLC | $49 952 700 | 630 000 | 0,46% | Option d'achat |
| NEUBERGER BERMAN GROUP LLC | $46 951 653 | 592 151 | 0,43% | Actions |
| EVENTIDE ASSET MANAGEMENT, LLC | $45 591 750 | 575 000 | 0,42% | Actions |
| PERCEPTIVE ADVISORS LLC | $44 878 140 | 566 000 | 0,42% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $44 355 936 | 559 414 | 0,41% | Actions |
| JANE STREET GROUP, LLC | $44 045 595 | 555 500 | 0,41% | Option d'achat |
| JANE STREET GROUP, LLC | $43 070 328 | 543 200 | 0,40% | Option de vente |
| TEACHER RETIREMENT SYSTEM OF TEXAS | $41 414 514 | 522 317 | 0,38% | Actions |
| BOONE CAPITAL MANAGEMENT LLC | $41 228 976 | 519 977 | 0,38% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $39 648 965 | 500 050 | 0,37% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $36 049 119 | 454 649 | 0,33% | Actions |
| Candriam S.C.A. | $35 251 607 | 445 019 | 0,33% | Actions |
| FIRST TRUST ADVISORS LP | $33 872 360 | 427 197 | 0,31% | Actions |
| PINNACLE ASSOCIATES LTD | $33 282 136 | 419 752 | 0,31% | Actions |
| BANK OF AMERICA CORP /DE/ | $32 643 138 | 411 693 | 0,30% | Actions |
| NOMURA HOLDINGS INC | $31 889 804 | 402 192 | 0,30% | Actions |
| Ikarian Capital, LLC | $31 716 000 | 400 000 | 0,29% | Option d'achat |
| CITADEL ADVISORS LLC | $30 645 585 | 386 500 | 0,28% | Option de vente |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $28 771 090 | 362 859 | 0,27% | Actions |
| BlackRock, Inc. | $28 184 582 | 355 462 | 0,26% | Actions |
| Caption Management, LLC | $27 426 411 | 345 900 | 0,25% | Option de vente |
| TD Asset Management Inc | $27 002 051 | 340 548 | 0,25% | Actions |
| Freestone Grove Partners LP | $26 955 983 | 339 967 | 0,25% | Actions |
| AXA Investment Managers S.A. | $26 590 024 | 406 451 | 0,25% | Actions |
| Qube Research & Technologies Ltd | $26 479 054 | 333 952 | 0,25% | Actions |
| Capital Research Global Investors | $26 319 205 | 331 936 | 0,24% | Actions |
| CAPITAL FUND MANAGEMENT S.A. | $26 130 336 | 329 554 | 0,24% | Actions |
| ALLIANCEBERNSTEIN L.P. | $25 564 391 | 340 450 | 0,24% | Actions |
| Carmignac Gestion | $25 452 090 | 321 000 | 0,24% | Actions |
| Privium Fund Management B.V. | $25 366 774 | 319 924 | 0,23% | Actions |
| Swiss National Bank | $24 976 350 | 315 000 | 0,23% | Actions |
| ARK Investment Management LLC | $23 848 064 | 300 770 | 0,22% | Actions |
| Integral Health Asset Management, LLC | $23 787 000 | 300 000 | 0,22% | Option d'achat |
| Ikarian Capital, LLC | $23 787 000 | 300 000 | 0,22% | Option de vente |
| MILLENNIUM MANAGEMENT LLC | $22 904 661 | 288 872 | 0,21% | Actions |
| DAVENPORT & Co LLC | $22 515 188 | 283 960 | 0,21% | Actions |
| Aberdeen Group plc | $21 995 046 | 277 400 | 0,20% | Actions |
| California Public Employees Retirement System | $21 475 141 | 270 843 | 0,20% | Actions |
| TimesSquare Capital Management, LLC | $20 700 361 | 275 674 | 0,19% | Actions |
| MILLENNIUM MANAGEMENT LLC | $20 417 175 | 257 500 | 0,19% | Option d'achat |
| TOCQUEVILLE ASSET MANAGEMENT L.P. | $19 918 837 | 251 215 | 0,18% | Actions |
| CITADEL ADVISORS LLC | $18 709 189 | 235 959 | 0,17% | Actions |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $18 514 136 | 233 499 | 0,17% | Actions |
| CITADEL ADVISORS LLC | $18 434 925 | 232 500 | 0,17% | Option d'achat |
| Orion Investment Co | $17 470 362 | 220 335 | 0,16% | Actions |
| Life Cycle Investment Partners Ltd | $17 435 554 | 219 896 | 0,16% | Actions |
| ALGERT GLOBAL LLC | $16 401 374 | 206 853 | 0,15% | Actions |
| Corient Private Wealth LP | $15 603 561 | 196 791 | 0,14% | Actions |
| Eagle Health Investments LP | $15 428 010 | 194 577 | 0,14% | Actions |
| SECTOR GAMMA AS | $15 022 918 | 189 468 | 0,14% | Actions |
| Polymer Capital Management (HK) LTD | $14 105 453 | 177 897 | 0,13% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $13 252 259 | 176 485 | 0,12% | Actions |
| ADAR1 Capital Management, LLC | $13 184 817 | 166 286 | 0,12% | Actions |
| RHUMBLINE ADVISERS | $13 075 750 | 164 911 | 0,12% | Actions |
| Sicart Associates LLC | $12 741 427 | 160 694 | 0,12% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $12 296 928 | 155 088 | 0,11% | Actions |
| CSS LLC/IL | $12 074 995 | 152 289 | 0,11% | Actions |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | $11 996 656 | 151 301 | 0,11% | Actions |
| CITIGROUP INC | $11 996 577 | 151 300 | 0,11% | Option d'achat |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $11 893 500 | 150 000 | 0,11% | Actions |
| Focus Partners Wealth | $11 728 366 | 147 917 | 0,11% | Actions |
| Hudson Bay Capital Management LP | $11 497 050 | 145 000 | 0,11% | Actions |
| Artia Global Partners LP | $11 447 573 | 144 376 | 0,11% | Actions |
| Sonora Investment Management Group, LLC | $11 108 840 | 169 808 | 0,10% | Actions |
| Fisher Asset Management, LLC | $10 877 317 | 137 184 | 0,10% | Actions |
| Atle Fund Management AB | $10 873 116 | 137 131 | 0,10% | Actions |
Initiés de la société 48 initiés · 30 dirigeants · 19 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Brett P Monia | Chief Executive Officer | 26 juin 2026 M | 245 571 | 0 | 17 | $-42 648 430 |
| HOUGEN ELIZABETH L | EVP, Finance & CFO | 16 mars 2026 M | 82 660 | 0 | 6 | $-21 117 075 |
| Kleanthis G Xanthopoulos | President of Regulus | 3 décembre 2007 A | — | 0 | 0 | $0 |
| Holly B. Kordasiewicz | EVP, Chief Development Officer | 7 juillet 2026 S | 22 096 | 0 | 4 | $-4 810 107 |
| BENNETT C FRANK | EVP, Chief Scientific Officer | 7 juillet 2026 J | 0 | 0 | 14 | $-19 804 154 |
| Eugene Schneider | EVP, Chf Clinical Develop Ofcr | 26 juin 2026 M | 77 114 | 0 | 6 | $-4 933 991 |
| Joseph Baroldi | EVP, Chief Business Officer | 26 juin 2026 M | 4 669 | 0 | 17 | $-6 405 525 |
| O'NEIL PATRICK R. | EVP CLO & General Counsel | 26 juin 2026 S | 61 470 | 0 | 16 | $-16 034 086 |
| Eric Swayze | EVP Research | 25 juin 2026 S | 21 759 | 0 | 14 | $-8 058 784 |
| Brian Birchler | EVP, Corp and Development Ops | 15 avril 2026 M | 67 500 | 0 | 6 | $-3 556 351 |
| Kyle Jenne | EVP, Chf GL Pdt Str Ofcr | 15 avril 2026 M | 23 713 | 0 | 4 | $-3 334 240 |
| Shannon L. Devers | EVP, Chief Human Resources Ofc | 2 avril 2026 S | 16 348 | 0 | 15 | $-8 854 430 |
| Richard S Geary | EVP, Chief Development Officer | 6 novembre 2025 M | 59 657 | 0 | 13 | $-13 858 595 |
| Onaiza Cadoret-Manier | EVP,Chf GL Pdt Str & Oper Ofc | 2 février 2024 S | 35 788 | 0 | 0 | $0 |
| Stanley T Crooke | Exec Chairman of the Board | 26 janvier 2021 S | 2 021 | 0 | 0 | $0 |
| Damien Mcdevitt | Chief Business Officer | 15 juillet 2019 M | 2 573 | 0 | 0 | $0 |
| Sarah Boyce | Chief Business Officer | 15 janvier 2018 M | 8 931 | 0 | 0 | $0 |
| ECKER DAVID J | Vice President | 2 septembre 2008 M | 0 | 0 | 0 | $0 |
| Michael J Treble | Vice President, Pres of Ibis | 11 août 2008 M | 0 | 0 | 0 | $0 |
| Jeffrey M Jonas | Executive Vice President | 2 janvier 2008 A | — | 0 | 0 | $0 |
| Mark K Wedel | VP & Chief Medical Officer | 6 juillet 2007 M | 6 603 | 0 | 0 | $0 |
| LEVIN ARTHUR A | Vice President | 25 avril 2007 M | 1 674 | 0 | 0 | $0 |
| BROWN RICHARD K | Vice President | 8 mars 2006 M | 2 348 | 0 | 0 | $0 |
| MCNEIL JOHN A | Vice President | 3 janvier 2005 A | — | 0 | 0 | $0 |
| LOWENSTAM PATRICIA | Vice President | 3 janvier 2005 A | 603 | 0 | 0 | $0 |
| STEIN ARON | Vice President | 1 juillet 2004 J | 1 536 | 0 | 0 | $0 |
| Hans A De Haan | VP, Drug Development | 27 avril 2004 S | 0 | 0 | 0 | $0 |
| LUNDSTEDT KAREN S | Vice President | 10 mars 2004 M | 5 407 | 0 | 0 | $0 |
| COLE DOUGLAS L | Vice President | 9 mars 2004 M | 9 616 | 0 | 0 | $0 |
| HOLMLUND JON T | Vice President | 1 juillet 2003 J | 983 | 0 | 0 | $0 |
| Michael R Hayden | Administrateur | 31 juillet 2026 P | 24 000 | 2 | 0 | $1 058 700 |
| Peter N Reikes | Administrateur | 15 juillet 2026 A | 14 222 | 0 | 0 | $0 |
| Ludwig Hantson | Administrateur | 15 juillet 2026 A | — | 0 | 0 | $0 |
| Joan E Herman | Administrateur | 15 juillet 2026 M | 51 306 | 0 | 2 | $-3 173 720 |
| BERTHELSEN SPENCER R | Administrateur | 15 juillet 2026 M | 161 233 | 0 | 2 | $-1 193 280 |
| Allene M. Diaz | Administrateur | 7 juillet 2026 M | 3 811 | 0 | 5 | $-5 278 717 |
| Michael J. Yang | Administrateur | 1 juillet 2026 A | 7 940 | 0 | 0 | $0 |
| Joseph Loscalzo | Administrateur | 1 juillet 2026 A | 36 330 | 0 | 6 | $-8 047 872 |
| Joseph Klein III | Administrateur | 1 juillet 2026 A | 11 014 | 0 | 14 | $-9 356 036 |
| Lynne B Parshall | Administrateur | 15 avril 2026 S | 51 344 | 0 | 6 | $-2 171 964 |
| Joseph H Wender | Administrateur | 1 décembre 2025 S | 36 035 | 0 | 13 | $-8 660 283 |
| MUTO FREDERICK T | Administrateur | 15 juillet 2022 M | 59 597 | 0 | 0 | $0 |
| Breaux Castleman | Administrateur | 1 juillet 2020 A | 19 183 | 0 | 0 | $0 |
| REED JOHN C | Administrateur | 6 septembre 2012 M | 0 | 0 | 0 | $0 |
| Richard D Dimarchi | Administrateur | 1 juillet 2010 A | — | 0 | 0 | $0 |
| GARIELI CHRISTOPHER | Administrateur | 1 juillet 2005 A | 155 431 | 0 | 0 | $0 |
| SKALETSKY MARK B | Administrateur | 1 juillet 2004 A | — | 0 | 0 | $0 |
| ISIS PHARMACEUTICALS INC | Détenteur de 10% | 10 octobre 2020 P | 98 322 397 | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 5 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| Ionis Pharmaceuticals, Inc. (“Ionis”) ×8 dépôts | 13 octobre 2020 | — | Dépôt initial | — | SEC |
| Isis Pharmaceuticals, Inc. (“ Isis ”) | 31 juillet 2015 | — | Dépôt initial | — | SEC |
| Isis Pharmaceuticals, Inc. (“Isis”), Stanley T. Crooke (“Crooke”), B. Lynne Parshall (“Parshall”) ×2 dépôts | 6 novembre 2014 | — | Dépôt initial | — | SEC |
| Genzyme Corporation | 15 janvier 2008 | — | Dépôt initial | Investissement passif | SEC |
| Personne déclarante non divulguée | 12 avril 2001 | — | Dépôt initial | Investissement passif | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 85 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| ARKG · ARK ETF Trust | 1,74% | 288 230 NS | 30 avril 2026 | N-PORT |
| FXH · First Trust Exchange-Traded AlphaDE… | 1,72% | 201 598 NS | 30 avril 2026 | N-PORT |
| BBP · ETFis Series Trust I | 1,48% | 11 708 NS | 30 avril 2026 | N-PORT |
| GDOC · Goldman Sachs ETF Trust | 1,37% | 3 614 NS | 31 mai 2026 | N-PORT |
| CGMM · Capital Group Equity ETF Trust I | 1,14% | 414 653 NS | 31 mai 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,94% | 64 911 NS | 30 avril 2026 | N-PORT |
| NUSC · Nushares ETF Trust | 0,87% | 150 398 NS | 30 avril 2026 | N-PORT |
| TAX · EA Series Trust | 0,87% | 2 885 NS | 29 mai 2026 | N-PORT |
| JDOC · J.P. Morgan Exchange-Traded Fund Tr… | 0,84% | 1 257 NS | 30 avril 2026 | N-PORT |
| COPY · RBB Fund Trust | 0,84% | 37 653 NS | 31 mai 2026 | N-PORT |
| HRTS · Tema ETF Trust | 0,83% | 5 599 NS | 31 mai 2026 | N-PORT |
| IBB · iShares Trust | 0,68% | 1 189 984 SH | 8 août 2026 | Quotidien |
| FFND · Northern Lights Fund Trust II | 0,67% | 9 000 NS | 31 mai 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,64% | 8 994 SH | 8 août 2026 | Quotidien |
| BIB · ProShares Trust | 0,63% | 6 109 NS | 31 mai 2026 | N-PORT |
| MEDI · Harbor ETF Trust | 0,58% | 2 153 NS | 30 avril 2026 | N-PORT |
| FDMO · FIDELITY COVINGTON TRUST | 0,53% | 60 169 NS | 30 avril 2026 | N-PORT |
| FNY · First Trust Exchange-Traded AlphaDE… | 0,53% | 36 525 NS | 30 avril 2026 | N-PORT |
| OASC · Unified Series Trust | 0,47% | 5 182 NS | 31 mai 2026 | N-PORT |
| QQQJ · Invesco Exchange-Traded Fund Trust … | 0,45% | 94 260 SH | 8 août 2026 | Quotidien |
| CGGR · Capital Group Growth ETF | 0,36% | 1 150 284 NS | 31 mai 2026 | N-PORT |
| VBK · VANGUARD INDEX FUNDS | 0,34% | 2 078 639 SH | 8 août 2026 | Quotidien |
| SMMV · iShares Trust | 0,32% | 17 089 SH | 8 août 2026 | Quotidien |
| BKMC · BNY Mellon ETF Trust | 0,30% | 25 160 NS | 30 avril 2026 | N-PORT |
| ISCG · iShares Trust | 0,28% | 51 765 SH | 8 août 2026 | Quotidien |
| SCHA · SCHWAB STRATEGIC TRUST | 0,26% | 778 644 NS | 31 mai 2026 | N-PORT |
| IWP · iShares Trust | 0,24% | 895 755 SH | 8 août 2026 | Quotidien |
| SCHM · SCHWAB STRATEGIC TRUST | 0,23% | 438 447 NS | 31 mai 2026 | N-PORT |
| FSMD · FIDELITY COVINGTON TRUST | 0,23% | 71 810 NS | 30 avril 2026 | N-PORT |
| BBMC · J.P. Morgan Exchange-Traded Fund Tr… | 0,22% | 60 227 NS | 30 avril 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,22% | 110 695 SH | 8 août 2026 | Quotidien |
| JMOM · J.P. Morgan Exchange-Traded Fund Tr… | 0,21% | 62 392 NS | 30 avril 2026 | N-PORT |
| FFLG · FIDELITY COVINGTON TRUST | 0,21% | 16 403 NS | 30 avril 2026 | N-PORT |
| FNX · First Trust Exchange-Traded AlphaDE… | 0,20% | 36 263 NS | 30 avril 2026 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0,20% | 50 927 SH | 8 août 2026 | Quotidien |
| FHLC · FIDELITY COVINGTON TRUST | 0,19% | 70 978 NS | 30 avril 2026 | N-PORT |
| VHT · VANGUARD WORLD FUND | 0,18% | 471 609 SH | 8 août 2026 | Quotidien |
| SMLF · iShares Trust | 0,17% | 133 297 SH | 8 août 2026 | Quotidien |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,16% | 10 044 NS | 30 avril 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,15% | 1 895 610 SH | 8 août 2026 | Quotidien |
| VB · VANGUARD INDEX FUNDS | 0,15% | 3 600 281 SH | 8 août 2026 | Quotidien |
| ESML · iShares Trust | 0,15% | 78 764 SH | 8 août 2026 | Quotidien |
| IYH · iShares Trust | 0,15% | 98 412 SH | 8 août 2026 | Quotidien |
| NBCR · Neuberger Berman ETF Trust | 0,14% | 16 581 NS | 31 mai 2026 | N-PORT |
| ISCB · iShares Trust | 0,14% | 7 328 SH | 8 août 2026 | Quotidien |
| AVIE · AMERICAN CENTURY ETF TRUST | 0,13% | 176 NS | 31 mai 2026 | N-PORT |
| SMMD · iShares Trust | 0,12% | 81 988 SH | 8 août 2026 | Quotidien |
| WSML · iShares Trust | 0,08% | 9 548 SH | 8 août 2026 | Quotidien |
| LRND · New York Life Investments ETF Trust | 0,07% | 2 788 NS | 30 avril 2026 | N-PORT |
| EQAL · Invesco Exchange-Traded Fund Trust … | 0,07% | 9 928 SH | 8 août 2026 | Quotidien |