PRAX Praxis Precision Medicines, Inc. - Common Stock
$372,10
Prix · Aoû 18, 2026
Données fondamentales au Aoû 6, 2026
Fourchette 52 semaines
$37–$388
95% of range
Note des analystes
BUY
25 analysts
Objectif de cours
$624
+68% upside
P/E (TTM)
-30.5
ROE
-47.3%
Marge nette
—
PRAX Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
Prix
$372.10
Capitalisation Boursière
$10.37B
P/E (TTM)
-30.5
BPA (TTM)
$-13.48
Revenus (TTM)
$0
Rendement div.
—
ROE
-47.3%
Dette/Capitaux propres
—
Fourchette 52 semaines
$37 – $388
PRAX Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Configure
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Revenus et bénéfice net
$0
2022-12-31
→
2025-12-31
BPA
$-13.48
2020-12-31
→
2025-12-31
Flux de trésorerie libre
$-249M
2020-12-31
→
2025-12-31
Marges
—
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Métrique
Tendance sur 5 ans
PRAX
Médiane des pairs
P/E (TTM)
-30.5
28.5
P/B
11.8
12.9
Price / FCF (Cours / FCF)
-41.6
—
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Métrique
Tendance sur 5 ans
PRAX
Médiane des pairs
ROA
-42.7%
-28.4%
ROE
-47.3%
-49.2%
ROIC
-37.2%
—
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Métrique
Tendance sur 5 ans
PRAX
Médiane des pairs
Current Ratio (Ratio de liquidité)
10.2
5.0
Quick Ratio (Ratio de liquidité réduite)
10.0
—
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Métrique
Tendance sur 5 ans
PRAX
Médiane des pairs
Revenue YoY (Chiffre d'affaires YoY)
249.5%
—
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
Métrique
Tendance sur 5 ans
PRAX
Médiane des pairs
PRAX Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
ACHAT
25 analystes
- Achat fort 9 36,0%
- Achat 13 52,0%
- Conserver 2 8,0%
- Vente 0 0,0%
- Vente forte 1 4,0%
Objectif de cours à 12 mois
19 analystes · 2026-08-15
Médiane
$550.00
Maintenant
$372.10
Bas
$188.00
Haut
$1201.00
Objectif médian
$550.00
+47,8%
Objectif moyen
$623.68
+67,6%
Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
Surprise Moyenne
0.19%
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-2.87 | $-3.73 | 0.86% |
| 31 mars 2026 | $-3.20 | $-3.62 | 0.42% |
| 31 décembre 2025 | $-3.50 | $-3.16 | -0.34% |
| 30 septembre 2025 | $-3.36 | $-3.51 | 0.15% |
| 30 juin 2025 | $-3.31 | $-3.40 | 0.09% |
| 31 mars 2025 | $-3.29 | $-3.27 | -0.03% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| PRAX | $7.43B | -21.9 | 249.5% | — | -47.3% | — |
| EXEL | $11.44B | 15.7 | 7.0% | 33.7% | 37.3% | — |
| ARWR | $4.68B | -3449.0 | 23258.2% | -0.20% | -0.50% | — |
| MDGL | $13.30B | -45.3 | 432.1% | -30.1% | -44.4% | — |
| HALO | $7.93B | 26.3 | 37.5% | 22.7% | 166.1% | — |
| CYTK | $7.81B | -9.7 | 376.6% | -891.6% | 152.7% | — |
| APGE | $5.16B | -17.9 | — | — | — | — |
| PTGX | $5.47B | -42.6 | -89.4% | -282.8% | -20.3% | — |
| KRYS | $7.20B | 36.0 | 33.9% | 52.6% | 18.1% | — |
| KYMR | $6.33B | -21.1 | -16.7% | -794.0% | -24.4% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 14
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue | $0 | $9M | $2M | $0 | |
| R&D Expense | $267M | $152M | $87M | $155M | |
| SG&A Expense | $59M | $56M | $42M | $60M | |
| Operating Expenses | $326M | $209M | $129M | $215M | |
| Operating Income | $-326M | $-200M | $-126M | $-215M | |
| Other Non-op | $23M | $17M | $3M | $957.0K | |
| Pretax Income | $-303M | $-183M | $-123M | · | |
| Income Tax | $471.0K | · | · | · | |
| Net Income | $-303M | $-183M | $-123M | $-214M | |
| EPS (Basic) | $-13.48 | $-10.21 | $-18.69 | $-69.65 | |
| EPS (Diluted) | $-13.48 | $-10.21 | $-18.69 | $-69.65 | |
| Shares (Basic) | 22,504,676 | 17,906,794 | 6,594,316 | 3,073,100 | |
| Shares (Diluted) | 22,504,676 | 17,906,794 | 6,594,316 | 3,073,100 | |
| EBITDA | $-326M | $-200M | $-126M | $-215M |
Bilan 22
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $357M | $215M | $81M | $62M | |
| Short-term Investments | $242M | $177M | · | · | |
| Prepaid Expense | $12M | $12M | $4M | $10M | |
| Current Assets | $611M | $404M | $85M | $111M | |
| PP&E (Net) | $147.0K | $230.0K | $588.0K | $971.0K | |
| PP&E (Gross) | $2M | $2M | $2M | $2M | |
| Accum. Depreciation | $2M | $1M | $1M | $572.0K | |
| Intangibles | $0 | · | · | · | |
| Other Non-current Assets | $0 | $416.0K | $416.0K | $416.0K | |
| Total Assets | $938M | $483M | $88M | $115M | |
| Accounts Payable | $25M | $13M | $6M | $15M | |
| Accrued Liabilities | $35M | $24M | $7M | $16M | |
| Current Liabilities | $60M | $38M | $16M | $34M | |
| Capital Leases | $0 | $110.0K | $1M | $2M | |
| Total Liabilities | $60M | $38M | $18M | $39M | |
| Common Stock | $15.0K | $14.0K | $13.0K | $5.0K | |
| Paid-in Capital | $2.02B | $1.28B | $724M | $607M | |
| Retained Earnings | $-1.14B | $-837M | $-654M | $-531M | |
| AOCI | $563.0K | $654.0K | $0 | $-173.0K | |
| Stockholders' Equity | $878M | $445M | $70M | $76M | |
| Liabilities + Equity | $938M | $483M | $88M | $115M | |
| Shares Outstanding | 25,195,092 | 19,422,358 | 8,791,877 | 3,292,163 |
Flux de trésorerie 10
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Stock-based Comp | $34M | $41M | $25M | $29M | |
| Operating Cash Flow | $-249M | $-132M | $-111M | $-185M | |
| CapEx | $56.0K | $0 | $50.0K | $444.0K | |
| Investing Cash Flow | $-311M | $-248M | $39M | $97M | |
| Stock Issued | · | · | · | $0 | |
| Net Stock Activity | · | · | · | $0 | |
| Financing Cash Flow | $702M | $514M | $92M | $10M | |
| Net Change in Cash | $142M | $134M | $20M | $-78M | |
| Taxes Paid | $224.0K | · | · | · | |
| Free Cash Flow | $-249M | $-132M | $-111M | $-185M |
Rentabilité 6
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Operating Margin | · | -2340.3% | -5164.4% | · | |
| Net Margin | · | -2137.5% | -5037.9% | · | |
| EBITDA Margin | · | -2340.3% | -5164.4% | · | |
| ROA | -42.7% | -64.0% | -121.4% | -105.0% | |
| ROE | -47.3% | -44.1% | -157.6% | -236.2% | |
| ROIC | -37.2% | · | · | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 10.2 | 10.8 | 5.4 | 3.2 | |
| Quick Ratio | 10.0 | 5.7 | 5.2 | 1.8 |
Efficacité 1
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | 0.0 | · |
Taux de croissance 1
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue YoY | · | 249.5% | · | · |
Valorisation (TTM) 10
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue TTM | $0 | $9M | $2M | $0 | |
| Net Income TTM | $-303M | $-183M | $-123M | $-214M | |
| Market Cap | $7.43B | $1.49B | $196M | $1.76B | |
| P/E | -21.9 | -7.5 | -1.2 | -0.5 | |
| P/S | · | 174.8 | 80.1 | · | |
| P/B | 8.5 | 3.4 | 2.8 | 23.2 | |
| P / Tangible Book | 8.5 | 3.4 | 2.8 | 23.2 | |
| P / Cash Flow | -29.8 | -11.3 | -1.8 | -9.5 | |
| P / FCF | -29.8 | -11.3 | -1.8 | -9.5 | |
| Earnings Yield | -4.6% | -13.3% | -83.9% | -195.1% |
Compte de résultat 14
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | $0 | $0 | $0 | $0 | $7M | $302.0K | $357.0K | $431.0K | $515.0K | $468.0K | $781.0K | $683.0K | $0 | $0 | |
| R&D Expense | $69M | $78M | $78M | $66M | $63M | $61M | $56M | $42M | $27M | $27M | $18M | $17M | $26M | $26M | $28M | $30M | |
| SG&A Expense | $27M | $28M | $20M | $13M | $13M | $14M | $15M | $15M | $11M | $15M | $10M | $9M | $10M | $13M | $13M | $14M | |
| Operating Expenses | $97M | $106M | $97M | $78M | $76M | $75M | $71M | $57M | $38M | $42M | $28M | $26M | $36M | $39M | $41M | $44M | |
| Operating Income | $-97M | $-106M | $-97M | $-78M | $-76M | $-75M | $-64M | $-57M | $-37M | $-42M | $-28M | $-26M | $-35M | $-38M | $-41M | $-44M | |
| Other Non-op | $13M | $13M | $8M | $4M | $5M | $5M | $5M | $5M | $5M | $2M | $928.0K | $884.0K | $648.0K | $636.0K | $280.0K | $345.0K | |
| Pretax Income | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $-44M | |
| Income Tax | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | |
| Net Income | $-84M | $-93M | $-89M | $-74M | $-71M | $-69M | $-59M | $-52M | $-33M | $-40M | $-27M | $-25M | $-34M | $-37M | $-41M | $-44M | |
| EPS (Basic) | $-2.87 | $-3.20 | $-3.52 | $-3.36 | $-3.31 | $-3.29 | $-2.88 | $-2.75 | $-1.74 | $-2.84 | $1.99 | $-2.72 | $-7.38 | $-10.58 | $-65.86 | $-0.96 | |
| EPS (Diluted) | $-2.87 | $-3.20 | $-3.52 | $-3.36 | $-3.31 | $-3.29 | $-2.88 | $-2.75 | $-1.74 | $-2.84 | $1.99 | $-2.72 | $-7.38 | $-10.58 | $-65.86 | $-0.96 | |
| Shares (Basic) | 29,131,375 | 28,883,596 | -42,003,253 | 21,977,268 | 21,474,827 | 21,055,834 | -33,706,621 | 18,884,562 | 18,824,479 | 13,904,374 | -10,634,667 | 9,039,427 | 4,649,371 | 3,540,185 | -133,699,055 | 45,774,376 | |
| Shares (Diluted) | 29,131,375 | 28,883,596 | -42,003,253 | 21,977,268 | 21,474,827 | 21,055,834 | -33,706,621 | 18,884,562 | 18,824,479 | 13,904,374 | -10,634,667 | 9,039,427 | 4,649,371 | 3,540,185 | -133,699,055 | 45,774,376 | |
| EBITDA | $-97M | $-106M | · | $-78M | $-76M | $-75M | · | $-57M | $-37M | $-42M | · | $-26M | $-35M | $-38M | · | $-44M |
Bilan 22
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $475M | $536M | $357M | $150M | $157M | $166M | $215M | $169M | $145M | $152M | $81M | $101M | $124M | $81M | $62M | $62M | |
| Short-term Investments | $284M | $251M | $242M | · | · | · | $177M | · | · | · | · | · | · | · | · | · | |
| Prepaid Expense | $13M | $11M | $12M | $7M | $5M | $6M | $12M | $3M | $5M | $4M | · | $2M | $6M | $9M | $10M | $9M | |
| Current Assets | $772M | $798M | $611M | $274M | $307M | $334M | $404M | $360M | $357M | $212M | · | $103M | $130M | $94M | $111M | $132M | |
| PP&E (Net) | $492.0K | $170.0K | $147.0K | $174.0K | $258.0K | $247.0K | $230.0K | $277.0K | $369.0K | $476.0K | · | $700.0K | $759.0K | $865.0K | $971.0K | $1M | |
| PP&E (Gross) | · | · | $2M | · | · | · | $2M | · | · | · | · | · | · | · | $2M | · | |
| Accum. Depreciation | · | · | $2M | · | · | · | $1M | · | · | · | · | · | · | · | $572.0K | · | |
| Intangibles | $773.0K | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Other Non-current Assets | $643.0K | · | $0 | $0 | $0 | $0 | $416.0K | $416.0K | $416.0K | $416.0K | · | $416.0K | $416.0K | $416.0K | $416.0K | $416.0K | |
| Total Assets | $1.39B | $1.46B | $938M | $396M | $453M | $479M | $483M | $416M | $441M | $250M | · | $107M | $133M | $98M | $115M | $137M | |
| Accounts Payable | $23M | $31M | $25M | $31M | $29M | $23M | $13M | $15M | $8M | $9M | · | $7M | $8M | $17M | $15M | $10M | |
| Accrued Liabilities | $25M | $18M | $35M | $22M | $19M | $16M | $24M | $15M | $10M | $7M | · | $7M | $13M | $9M | $16M | $18M | |
| Current Liabilities | $49M | $50M | $60M | $53M | $49M | $40M | $38M | $33M | $21M | $19M | · | $17M | $24M | $30M | $34M | $29M | |
| Capital Leases | · | · | $0 | $0 | $0 | $0 | $110.0K | $436.0K | $755.0K | $1M | · | $2M | $2M | $2M | $2M | $3M | |
| Total Liabilities | $49M | $50M | $60M | $53M | $49M | $40M | $38M | $34M | $22M | $21M | · | $20M | $28M | $34M | $39M | $32M | |
| Common Stock | $15.0K | $15.0K | $15.0K | $14.0K | $14.0K | $14.0K | $14.0K | $14.0K | $14.0K | $13.0K | · | $13.0K | $13.0K | $6.0K | $5.0K | $5.0K | |
| Paid-in Capital | $2.66B | $2.64B | $2.02B | $1.39B | $1.38B | $1.34B | $1.28B | $1.16B | $1.15B | $923M | · | $714M | $708M | $633M | $607M | $595M | |
| Retained Earnings | $-1.32B | $-1.23B | $-1.14B | $-1.05B | $-977M | $-906M | $-837M | $-778M | $-726M | $-693M | · | $-627M | $-602M | $-568M | $-531M | $-489M | |
| AOCI | $-3M | $-2M | $563.0K | $500.0K | $395.0K | $659.0K | $654.0K | $1M | $-71.0K | $3.0K | · | $0 | $0 | $-19.0K | $-173.0K | $-536.0K | |
| Stockholders' Equity | $1.34B | $1.41B | $878M | $344M | $404M | $439M | $445M | $383M | $419M | $230M | $70M | $87M | $106M | $64M | $76M | $105M | |
| Liabilities + Equity | $1.39B | $1.46B | $938M | $396M | $453M | $479M | $483M | $416M | $441M | $250M | · | $107M | $133M | $98M | $115M | $137M | |
| Shares Outstanding | 27,916,593 | 27,859,514 | 25,195,092 | 21,165,933 | 21,040,474 | 20,341,917 | 19,422,358 | 17,785,697 | 17,755,506 | 13,258,047 | 8,791,877 | 128,547,336 | 128,540,223 | 57,960,387 | 3,292,163 | 46,864,327 |
Flux de trésorerie 7
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $11M | $17M | $10M | $7M | $8M | $9M | $9M | $12M | $6M | $14M | $6M | $6M | $6M | $8M | $6M | $7M | |
| Operating Cash Flow | $-78M | $-86M | $-76M | $-65M | $-55M | $-53M | $-56M | $-28M | $-27M | $-21M | $-24M | $-23M | $-31M | $-33M | $-29M | $-45M | |
| CapEx | $245.0K | $62.0K | $0 | $0 | $56.0K | $0 | $0 | $0 | · | · | $50.0K | $0 | $0 | $0 | $0 | $45.0K | |
| Investing Cash Flow | $11M | $-344M | $-328M | $50M | $18M | $-51M | $-11M | $50M | $-196M | $-91M | $-50.0K | $0 | $5M | $34M | $23M | $48M | |
| Financing Cash Flow | $5M | $609M | $613M | $7M | $29M | $54M | $114M | $1M | $216M | $183M | $4M | $0 | $70M | $18M | $5M | $3M | |
| Net Change in Cash | $-62M | $179M | $208M | $-8M | $-8M | $-50M | $47M | $24M | $-7M | $71M | $-20M | $-23M | $43M | $19M | $-825.0K | $6M | |
| Free Cash Flow | · | $-86M | · | · | · | · | · | · | · | · | · | · | · | $-33M | · | · |
Rentabilité 6
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | -18819.5% | -10500.8% | -9718.3% | · | -5452.1% | -4476.3% | -5577.0% | · | · | |
| Net Margin | · | · | · | · | · | · | · | -17188.7% | -9153.2% | -9177.0% | · | -5263.2% | -4393.3% | -5483.9% | · | · | |
| EBITDA Margin | · | · | · | · | · | · | · | -18819.5% | -10500.8% | -9718.3% | · | -5452.1% | -4476.3% | -5577.0% | · | · | |
| ROA | -9.1% | -9.6% | · | -18.2% | -15.9% | -19.0% | · | -19.9% | -11.4% | -22.7% | · | -20.2% | -21.9% | -22.2% | · | -19.1% | |
| ROE | -9.6% | -10.0% | · | -20.4% | -17.3% | -20.7% | · | -22.1% | -12.4% | -26.9% | · | -25.7% | -28.1% | -29.3% | · | -21.9% | |
| ROIC | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | -42.1% |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 15.7 | 15.9 | · | 5.2 | 6.3 | 8.4 | · | 11.0 | 17.3 | 11.3 | · | 6.2 | 5.3 | 3.2 | · | 4.6 | |
| Quick Ratio | 15.5 | 15.7 | · | 2.8 | 3.2 | 4.2 | · | 5.1 | 7.0 | 8.1 | · | 6.0 | 5.1 | 2.7 | · | 2.2 |
Efficacité 1
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | · |
Valorisation (TTM) 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $302.0K | $302.0K | · | $302.0K | $659.0K | $1M | · | $2M | $2M | $2M | · | $2M | $1M | $683.0K | · | · | |
| Net Income TTM | $-321M | $-307M | · | $-273M | $-251M | $-213M | · | $-151M | $-124M | $-125M | · | $-138M | $-157M | $-183M | · | $-231M | |
| Market Cap | $9.35B | $8.98B | · | $1.12B | $885M | $770M | · | $1.02B | $734M | $809M | · | $3.30B | $2.22B | $703M | · | $1.60B | |
| P/E | -26.3 | -24.5 | · | -4.2 | -3.8 | -3.6 | · | -5.7 | -2.8 | -2.6 | · | -1.2 | -0.9 | -0.8 | · | -7.1 | |
| P/S | 30947.7 | 29722.0 | · | 3714.6 | 1342.6 | 706.7 | · | 656.9 | 360.5 | 342.4 | · | 1706.6 | 1514.6 | 1029.8 | · | · | |
| P/B | 7.0 | 6.4 | · | 3.3 | 2.2 | 1.8 | · | 2.7 | 1.8 | 3.5 | · | 38.0 | 21.0 | 10.9 | · | 15.2 | |
| P / Tangible Book | 7.0 | 6.4 | · | 3.3 | 2.2 | 1.8 | · | 2.7 | 1.8 | 3.5 | · | 38.0 | 21.0 | 10.9 | · | 15.2 | |
| P / Cash Flow | · | -104.2 | · | · | · | -14.5 | · | · | · | -38.8 | · | · | · | -21.4 | · | · | |
| P / FCF | · | -104.1 | · | · | · | · | · | · | · | · | · | · | · | -21.4 | · | · | |
| Earnings Yield | -3.8% | -4.1% | · | -24.0% | -26.4% | -28.0% | · | -17.5% | -35.5% | -38.5% | · | -84.4% | -117.3% | -118.4% | · | -14.1% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenu | $0 | $9M | $2M | $0 | — |
| Marge d'exploitation % | — | -2340.3% | -5164.4% | — | — |
| Résultat net | $-303M | $-183M | $-123M | $-214M | $-167M |
| BPA dilué | $-13.48 | $-10.21 | $-18.69 | $-69.65 | $-3.94 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 10.2 | 10.8 | 5.4 | 3.2 | 7.5 |
| Ratio de liquidité réduite | 10.0 | 5.7 | 5.2 | 1.8 | 3.6 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-249M | $-132M | $-111M | $-185M | $-126M |
Dernières actualités Actualités récentes mentionnant cette entreprise
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Détenteurs institutionnels (13F) 334 déclarants · $9.1B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
Activité institutionnelle — Q2 2026 vs trimestre précédent
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 68 (-11 vs T. préc.) | 38 (+7 vs T. préc.) | 113 (+2 vs T. préc.) | 103 (+21 vs T. préc.) | -721K |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | $1 086 154 856 | 3 373 916 | 11,95% | Actions |
| PERCEPTIVE ADVISORS LLC | $681 627 753 | 2 035 986 | 7,50% | Actions |
| FMR LLC | $661 132 579 | 1 974 768 | 7,27% | Actions |
| BAKER BROS. ADVISORS LP | $586 953 158 | 1 753 198 | 6,46% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $447 006 586 | 1 335 185 | 4,92% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $413 565 752 | 1 235 299 | 4,55% | Actions |
| VANGUARD GROUP INC | $377 765 605 | 1 281 691 | 4,16% | Actions |
| STATE STREET CORP | $343 656 004 | 1 026 443 | 3,78% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $339 972 549 | 1 015 480 | 3,74% | Actions |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $322 520 281 | 963 351 | 3,55% | Actions |
| Driehaus Capital Management LLC | $321 079 680 | 959 048 | 3,53% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $218 564 045 | 652 714 | 2,40% | Actions |
| Cormorant Asset Management, LP | $214 265 600 | 640 000 | 2,36% | Actions |
| BANK OF AMERICA CORP /DE/ | $174 683 713 | 521 771 | 1,92% | Actions |
| Hood River Capital Management LLC | $142 341 660 | 425 167 | 1,57% | Actions |
| GOLDMAN SACHS GROUP INC | $118 540 100 | 354 073 | 1,30% | Actions |
| NORGES BANK | $116 161 752 | 346 969 | 1,28% | Actions |
| Pictet Asset Management Holding SA | $98 035 469 | 291 689 | 1,08% | Actions |
| Polar Capital Holdings Plc | $93 450 267 | 279 131 | 1,03% | Actions |
| Vivo Capital, LLC | $90 766 926 | 271 116 | 1,00% | Actions |
| Logos Global Management LP | $87 045 400 | 260 000 | 0,96% | Actions |
| AMERICAN CENTURY COMPANIES INC | $79 451 539 | 237 315 | 0,87% | Actions |
| ORBIMED ADVISORS LLC | $77 035 179 | 230 100 | 0,85% | Actions |
| Caption Management, LLC | $75 260 792 | 224 800 | 0,83% | Option de vente |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $73 656 478 | 220 008 | 0,81% | Actions |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $73 284 861 | 218 898 | 0,81% | Actions |
| Verition Fund Management LLC | $67 326 269 | 201 100 | 0,74% | Option de vente |
| Woodline Partners LP | $66 962 352 | 200 013 | 0,74% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $63 077 449 | 188 409 | 0,69% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $62 994 421 | 188 161 | 0,69% | Actions |
| Affinity Asset Advisors, LLC | $61 936 150 | 185 000 | 0,68% | Actions |
| Soleus Capital Management, L.P. | $59 430 916 | 177 517 | 0,65% | Actions |
| Aberdeen Group plc | $55 708 721 | 166 399 | 0,61% | Actions |
| Qube Research & Technologies Ltd | $51 047 105 | 152 475 | 0,56% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $41 882 229 | 125 100 | 0,46% | Option de vente |
| 683 Capital Management, LLC | $36 960 816 | 110 400 | 0,41% | Option de vente |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $35 376 590 | 105 668 | 0,39% | Actions |
| MARSHALL WACE, LLP | $34 519 862 | 103 109 | 0,38% | Actions |
| Nantahala Capital Management, LLC | $33 479 000 | 100 000 | 0,37% | Option de vente |
| MetLife Investment Management, LLC | $30 312 891 | 90 543 | 0,33% | Actions |
| Velan Capital Investment Management LP | $29 722 991 | 88 781 | 0,33% | Actions |
| First Turn Management, LLC | $27 964 339 | 83 528 | 0,31% | Actions |
| ACUTA CAPITAL PARTNERS, LLC | $27 719 273 | 82 796 | 0,30% | Actions |
| Alyeska Investment Group, L.P. | $27 066 432 | 80 846 | 0,30% | Actions |
| ADAR1 Capital Management, LLC | $24 859 162 | 74 253 | 0,27% | Actions |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $24 843 762 | 74 207 | 0,27% | Actions |
| Ensign Peak Advisors, Inc | $24 423 600 | 72 952 | 0,27% | Actions |
| Ikarian Capital, LLC | $24 386 773 | 72 842 | 0,27% | Actions |
| NEUBERGER BERMAN GROUP LLC | $24 064 705 | 71 880 | 0,26% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $23 334 863 | 69 700 | 0,26% | Option d'achat |
| ALLIANCEBERNSTEIN L.P. | $23 042 384 | 71 518 | 0,25% | Actions |
| 72 Investment Holdings, LLC | $22 073 709 | 65 933 | 0,24% | Actions |
| SILVERARC CAPITAL MANAGEMENT, LLC | $21 988 672 | 65 679 | 0,24% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $21 629 108 | 64 605 | 0,24% | Actions |
| AMERIPRISE FINANCIAL INC | $20 654 868 | 61 695 | 0,23% | Actions |
| Candriam S.C.A. | $20 354 378 | 60 856 | 0,22% | Actions |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $19 029 464 | 56 840 | 0,21% | Actions |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $16 109 425 | 48 118 | 0,18% | Actions |
| Boxer Capital Management, LLC | $15 553 339 | 46 457 | 0,17% | Actions |
| Swiss National Bank | $15 433 819 | 46 100 | 0,17% | Actions |
| ArrowMark Colorado Holdings LLC | $15 410 384 | 46 030 | 0,17% | Actions |
| California Public Employees Retirement System | $15 189 422 | 45 370 | 0,17% | Actions |
| JANE STREET GROUP, LLC | $14 630 323 | 43 700 | 0,16% | Option de vente |
| KVP Capital Advisors, LP | $14 362 491 | 42 900 | 0,16% | Actions |
| SEB Asset Management AB | $14 297 180 | 42 705 | 0,16% | Actions |
| Squarepoint Ops LLC | $14 228 910 | 42 501 | 0,16% | Actions |
| Integral Health Asset Management, LLC | $13 391 600 | 40 000 | 0,15% | Actions |
| EVENTIDE ASSET MANAGEMENT, LLC | $12 956 962 | 38 684 | 0,14% | Actions |
| PFM Health Sciences, LP | $12 914 524 | 38 575 | 0,14% | Actions |
| STEMPOINT CAPITAL LP | $12 468 584 | 37 243 | 0,14% | Actions |
| Burkehill Global Management, LP | $11 717 650 | 35 000 | 0,13% | Actions |
| University of Wisconsin Foundation | $11 627 257 | 34 730 | 0,13% | Actions |
| BlackRock, Inc. | $11 180 647 | 33 396 | 0,12% | Actions |
| B Group, Inc. | $11 127 415 | 33 237 | 0,12% | Actions |
| Bank of New York Mellon Corp | $11 050 748 | 33 008 | 0,12% | Actions |
| RHUMBLINE ADVISERS | $10 829 433 | 32 347 | 0,12% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $10 570 659 | 31 574 | 0,12% | Actions |
| HighVista Strategies LLC | $10 114 006 | 30 210 | 0,11% | Actions |
| Clearbridge Investments, LLC | $9 367 759 | 27 981 | 0,10% | Actions |
| JANE STREET GROUP, LLC | $9 139 767 | 27 300 | 0,10% | Option d'achat |
| Exome Asset Management LLC | $9 107 962 | 27 205 | 0,10% | Actions |
| TD Asset Management Inc | $9 093 566 | 27 162 | 0,10% | Actions |
| CAPITAL FUND MANAGEMENT S.A. | $9 058 747 | 27 058 | 0,10% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $8 852 815 | 27 477 | 0,10% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $8 753 754 | 26 147 | 0,10% | Actions |
| WCM INVESTMENT MANAGEMENT, LLC | $8 672 504 | 24 739 | 0,10% | Actions |
| PEREGRINE CAPITAL MANAGEMENT LLC | $8 634 234 | 25 790 | 0,09% | Actions |
| CASTLEARK MANAGEMENT LLC | $8 165 528 | 24 390 | 0,09% | Actions |
| CITADEL ADVISORS LLC | $8 101 918 | 24 200 | 0,09% | Option de vente |
| VANGUARD ASSET MANAGEMENT, Ltd | $7 577 637 | 22 634 | 0,08% | Actions |
| Ishara Investments LP | $7 549 515 | 22 550 | 0,08% | Actions |
| Man Group plc | $7 085 496 | 21 164 | 0,08% | Actions |
| Susquehanna Portfolio Strategies, LLC | $7 072 774 | 21 126 | 0,08% | Actions |
| VOYA INVESTMENT MANAGEMENT LLC | $7 030 925 | 21 001 | 0,08% | Actions |
| Ikarian Capital, LLC | $6 695 800 | 20 000 | 0,07% | Option d'achat |
| SummitTX Capital, L.P. | $6 621 811 | 19 779 | 0,07% | Actions |
| Moody Aldrich Partners LLC | $6 383 106 | 19 066 | 0,07% | Actions |
| CITADEL ADVISORS LLC | $6 294 052 | 18 800 | 0,07% | Option d'achat |
| TWO SIGMA INVESTMENTS, LP | $6 279 991 | 18 758 | 0,07% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $6 015 507 | 17 968 | 0,07% | Actions |
Initiés de la société 16 initiés · 6 dirigeants · 10 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Marcio Souza | Chief Executive Officer | 8 juillet 2026 G | 0 | 0 | 0 | $0 |
| Timothy Edwin Kelly | Chief Financial Officer | 14 novembre 2025 A | 24 663 | 0 | 0 | $0 |
| Alex Nemiroff | General Counsel and Secretary | 20 novembre 2025 M | 20 832 | 0 | 4 | $-4 852 208 |
| Lauren Mastrocola | Principal Accounting Officer | 20 novembre 2025 M | 10 442 | 0 | 2 | $-2 612 265 |
| Nicole Sweeny | Chief Commercial Officer | 7 janvier 2022 A | 40 800 | 0 | 0 | $0 |
| Bernard Ravina | Chief Medical Officer | 7 janvier 2022 A | 102 533 | 0 | 0 | $0 |
| Jill Desimone | Administrateur | 24 juin 2026 M | 2 337 | 0 | 12 | $-3 611 315 |
| Merit Ester Cudkowicz | Administrateur | 10 juin 2026 A | 1 371 | 0 | 0 | $0 |
| Jeffrey Chodakewitz | Administrateur | 10 juin 2026 A | 1 371 | 0 | 0 | $0 |
| Stuart A Arbuckle | Administrateur | 10 juin 2026 A | 2 537 | 0 | 0 | $0 |
| Gregory Norden | Administrateur | 10 juin 2026 A | 1 559 | 0 | 0 | $0 |
| William D Young | Administrateur | 10 juin 2026 A | 3 269 | 0 | 0 | $0 |
| Dean J Mitchell | Administrateur | 10 juin 2026 A | 18 622 | 0 | 0 | $0 |
| Jeffrey B Kindler | Administrateur | 10 juin 2026 A | 2 537 | 0 | 0 | $0 |
| Stefan Vitorovic | Administrateur | 20 octobre 2020 C | 2 689 329 | 0 | 0 | $0 |
| Novo Holdings A/S | Détenteur de 10% | 20 octobre 2020 C | 2 442 080 | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 1 participation
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| Velan Capital Master Fund LP, Velan Capital Holdings LLC, Velan Capital Investment Management LP, Velan Capital Management LLC, Adam Morgan, Balaji Venkataraman ×2 dépôts | 28 juin 2023 | — | Dépôt initial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 60 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| IBRN · iShares Trust | 5,55% | 1 157 SH | 8 août 2026 | Quotidien |
| GNOM · Global X Funds | 4,01% | 6 388 NS | 31 mai 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 1,04% | 1 554 NS | 31 mai 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 1,00% | 16 345 NS | 30 avril 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,88% | 1 026 NS | 30 avril 2026 | N-PORT |
| IBB · iShares Trust | 0,74% | 191 676 SH | 8 août 2026 | Quotidien |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,68% | 1 515 SH | 8 août 2026 | Quotidien |
| IWO · iShares Trust | 0,57% | 228 086 SH | 8 août 2026 | Quotidien |
| GDOC · Goldman Sachs ETF Trust | 0,55% | 316 NS | 31 mai 2026 | N-PORT |
| MEDI · Harbor ETF Trust | 0,50% | 433 NS | 30 avril 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,50% | 26 912 SH | 8 août 2026 | Quotidien |
| BIB · ProShares Trust | 0,49% | 1 029 NS | 31 mai 2026 | N-PORT |
| ESSC · Strategy Shares | 0,44% | 353 NS | 30 avril 2026 | N-PORT |
| FNY · First Trust Exchange-Traded AlphaDE… | 0,39% | 6 384 NS | 30 avril 2026 | N-PORT |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,38% | 8 664 NS | 30 avril 2026 | N-PORT |
| BKSE · BNY Mellon ETF Trust | 0,34% | 859 NS | 30 avril 2026 | N-PORT |
| IWM · iShares Trust | 0,29% | 640 515 SH | 8 août 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,26% | 144 661 SH | 8 août 2026 | Quotidien |
| ISCG · iShares Trust | 0,25% | 6 781 SH | 8 août 2026 | Quotidien |
| RSSL · Global X Funds | 0,25% | 11 145 NS | 30 avril 2026 | N-PORT |
| ITWO · ProShares Trust | 0,23% | 1 215 NS | 31 mai 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,22% | 8 846 NS | 30 avril 2026 | N-PORT |
| VBR · VANGUARD INDEX FUNDS | 0,20% | 405 873 SH | 8 août 2026 | Quotidien |
| VFMO · VANGUARD WELLINGTON FUND | 0,20% | 11 745 SH | 8 août 2026 | Quotidien |
| SCHA · SCHWAB STRATEGIC TRUST | 0,19% | 123 726 NS | 31 mai 2026 | N-PORT |
| FNX · First Trust Exchange-Traded AlphaDE… | 0,14% | 5 633 NS | 30 avril 2026 | N-PORT |
| UWM · ProShares Trust | 0,13% | 951 NS | 31 mai 2026 | N-PORT |
| ESML · iShares Trust | 0,13% | 9 948 SH | 8 août 2026 | Quotidien |
| ISCB · iShares Trust | 0,12% | 964 SH | 8 août 2026 | Quotidien |
| FHLC · FIDELITY COVINGTON TRUST | 0,12% | 10 867 NS | 30 avril 2026 | N-PORT |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,12% | 1 757 NS | 30 avril 2026 | N-PORT |
| VB · VANGUARD INDEX FUNDS | 0,11% | 639 384 SH | 8 août 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | 0,11% | 69 046 SH | 8 août 2026 | Quotidien |
| VXF · VANGUARD INDEX FUNDS | 0,10% | 300 792 SH | 8 août 2026 | Quotidien |
| URTY · ProShares Trust | 0,10% | 963 NS | 31 mai 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,09% | 7 400 SH | 8 août 2026 | Quotidien |
| GSSC · Goldman Sachs ETF Trust | 0,09% | 2 420 NS | 31 mai 2026 | N-PORT |
| WSML · iShares Trust | 0,08% | 1 456 SH | 8 août 2026 | Quotidien |
| FBCG · FIDELITY COVINGTON TRUST | 0,07% | 13 678 NS | 30 avril 2026 | N-PORT |
| AVIE · AMERICAN CENTURY ETF TRUST | 0,05% | 16 NS | 31 mai 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,05% | 586 NS | 30 avril 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,04% | 949 NS | 31 mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,04% | 24 NS | 31 mai 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,03% | 12 964 NS | 30 avril 2026 | N-PORT |
| SMLF · iShares Trust | 0,03% | 2 982 SH | 8 août 2026 | Quotidien |
| ONEQ · Fidelity Commonwealth Trust | 0,02% | 6 831 NS | 31 mai 2026 | N-PORT |
| AVLC · AMERICAN CENTURY ETF TRUST | 0,02% | 720 NS | 31 mai 2026 | N-PORT |
| TILT · FlexShares Trust | 0,02% | 1 078 NS | 30 avril 2026 | N-PORT |
| ITOT · iShares Trust | 0,01% | 33 953 SH | 8 août 2026 | Quotidien |
| GUSA · Goldman Sachs ETF Trust II | 0,01% | 867 NS | 31 mai 2026 | N-PORT |