JBIO Jade Biosciences, Inc. - Common Stock
$23,20
Prix · Aoû 19, 2026
Données fondamentales au Aoû 10, 2026
Fourchette 52 semaines
$7–$28
77% of range
Note des analystes
STRONG BUY
17 analysts
Objectif de cours
$50
+116% upside
P/E (TTM)
-7.3
ROE
-47.7%
Marge nette
—
JBIO Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
Prix
$23.20
Capitalisation Boursière
$1.14B
P/E (TTM)
-7.3
BPA (TTM)
$-3.19
Revenus (TTM)
—
Rendement div.
—
ROE
-47.7%
Dette/Capitaux propres
—
Fourchette 52 semaines
$7 – $28
JBIO Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Configure
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Revenus et bénéfice net
—
BPA
$-3.19
2021-12-31
→
2025-12-31
Flux de trésorerie libre
$-95M
2021-12-31
→
2025-12-31
Marges
—
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Métrique
Tendance sur 5 ans
JBIO
Médiane des pairs
P/E (TTM)
-7.3
—
P/B
3.4
2.7
Price / FCF (Cours / FCF)
-12.1
—
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Métrique
Tendance sur 5 ans
JBIO
Médiane des pairs
ROA
-60.3%
-43.1%
ROE
-47.7%
-49.0%
ROIC
-34.2%
—
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Métrique
Tendance sur 5 ans
JBIO
Médiane des pairs
Current Ratio (Ratio de liquidité)
21.1
9.0
Quick Ratio (Ratio de liquidité réduite)
20.3
—
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Métrique
Tendance sur 5 ans
JBIO
Médiane des pairs
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
Métrique
Tendance sur 5 ans
JBIO
Médiane des pairs
Dividendes Rendement, ratio de distribution, historique des dividendes, CAGR à 5 ans
Rendement du Dividende
—
Ratio de distribution
—
CAGR des dividendes sur 5 ans
—
| Date ex-dividende | Montant |
|---|---|
| 29 avril 2025 | $2,4000 |
JBIO Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
ACHAT
17 analystes
- Achat fort 8 47,1%
- Achat 8 47,1%
- Conserver 1 5,9%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
8 analystes · 2026-08-14
Médiane
$47.00
Moyenne
$50.12
← En dessous de tous les objectifs
$23.20
Bas
$40.00
Haut
$77.00
Objectif médian
$47.00
+102,6%
Objectif moyen
$50.12
+116,1%
Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
Surprise Moyenne
1.0%
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 31 mars 2026 | $-0.57 | $-0.49 | -0.08% |
| 31 décembre 2025 | $-0.59 | $-0.48 | -0.11% |
| 30 septembre 2025 | $-0.48 | $-0.69 | 0.21% |
| 30 juin 2025 | $-0.86 | $-0.44 | -0.42% |
| 31 mars 2025 | $-3.15 | $-8.57 | 5.4% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| JBIO | $761M | -4.8 | — | — | -47.7% | — |
| PURR | — | — | — | — | — | — |
| VIR | $841M | -1.9 | -7.6% | -638.9% | -51.1% | — |
| ORIC | $806M | -5.6 | — | — | -36.5% | — |
| INBX | $1.15B | -8.7 | 550.0% | -10773.5% | -365.9% | — |
| AVBP | $854M | -4.7 | — | — | -59.7% | — |
| REPL | $633M | -2.3 | — | — | -146.2% | — |
| MGTX | $645M | -5.6 | 144.6% | -140.3% | 8062.2% | — |
| NVAX | $1.09B | 2.6 | 64.7% | 39.2% | -977.1% | — |
| CGEM | $624M | -3.2 | — | — | -44.0% | — |
| MNKD | $1.75B | 283.5 | 22.2% | 1.7% | -11.1% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 14
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $93M | $53M | $64M | $39M | $15M | $8M | |
| SG&A Expense | $20M | $21M | $17M | $15M | $8M | $949.0K | |
| Operating Expenses | $114M | $75M | $81M | $53M | $23M | $9M | |
| Operating Income | $-114M | $-75M | $-81M | $-53M | $-23M | $-9M | |
| Interest Expense | · | · | · | · | · | $75.0K | |
| Other Non-op | $-8.0K | $-19.0K | $-1.0K | $2M | $62.0K | $-722.0K | |
| Pretax Income | $-127M | $-70M | $-75M | $-51M | $-23M | $-10M | |
| Income Tax | $58.0K | $55.0K | $56.0K | $25.0K | $3.0K | · | |
| Net Income | $-127M | $-70M | $-76M | $-52M | $-23M | $-10M | |
| EPS (Basic) | $-3.19 | $-2.44 | $-2.87 | $-2.10 | $-1.87 | · | |
| EPS (Diluted) | $-3.19 | $-2.44 | $-2.87 | $-2.10 | $-1.87 | · | |
| Shares (Basic) | 31,359,958 | 28,582,194 | 26,331,630 | 24,472,104 | 12,293,629 | · | |
| Shares (Diluted) | 31,359,958 | 28,582,194 | 26,331,630 | 24,472,104 | 12,293,629 | · | |
| EBITDA | $-114M | $-75M | $-81M | $-53M | $-23M | · |
Bilan 21
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $88M | $69M | $23M | $22M | $54M | $5M | |
| Short-term Investments | $248M | $0 | $99M | $107M | $113M | · | |
| Prepaid Expense | $13M | $268.0K | $2M | $2M | $7M | $103.0K | |
| Current Assets | $349M | $70M | $124M | $131M | $174M | $5M | |
| PP&E (Net) | $170.0K | · | $288.0K | $242.0K | $186.0K | $39.0K | |
| PP&E (Gross) | · | · | · | · | · | $40.0K | |
| Accum. Depreciation | · | · | · | · | · | $1.0K | |
| Other Non-current Assets | $69.0K | $3M | $2M | $3M | $302.0K | · | |
| Total Assets | $350M | $73M | $127M | $135M | $175M | $5M | |
| Accounts Payable | $2M | $1M | $2M | $3M | $1M | $618.0K | |
| Accrued Liabilities | $9M | $4M | · | · | · | · | |
| Current Liabilities | $17M | $12M | $18M | $8M | $3M | $2M | |
| Capital Leases | $724.0K | $0 | $255.0K | $705.0K | $382.0K | · | |
| Total Liabilities | $17M | $120M | $18M | $9M | $3M | $2M | |
| Common Stock | $5.0K | $1.0K | $3.0K | $2.0K | $2.0K | · | |
| Paid-in Capital | $507M | $179.0K | $273M | $215M | $209M | $63.0K | |
| Retained Earnings | $-174M | $-47M | $-163M | $-88M | $-36M | $-13M | |
| AOCI | $129.0K | $0 | $237.0K | $-466.0K | $-59.0K | · | |
| Stockholders' Equity | $333M | $-47M | $109M | $127M | $172M | $-13M | |
| Liabilities + Equity | $350M | $73M | $127M | $135M | $175M | $5M | |
| Shares Outstanding | 49,316,287 | 3,672,794 | 27,762,703 | 24,722,974 | 24,410,393 | 243,076 |
Flux de trésorerie 10
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Stock-based Comp | $20M | $11M | $12M | $5M | $2M | $58.0K | |
| Deferred Tax | $-44.0K | · | · | · | · | · | |
| Operating Cash Flow | $-95M | $-71M | $-57M | $-39M | $-27M | $-8M | |
| CapEx | $196.0K | · | $142.0K | $195.0K | $181.0K | · | |
| Investing Cash Flow | $-247M | $56M | $12M | $7M | $-113M | · | |
| Stock Issued | · | $24M | $45M | · | $127M | · | |
| Net Stock Activity | · | $24M | $45M | · | $127M | · | |
| Financing Cash Flow | $361M | $25M | $46M | $396.0K | $190M | $9M | |
| Net Change in Cash | $19M | $10M | $1M | $-32M | $50M | $1M | |
| Free Cash Flow | $-95M | · | $-57M | $-39M | $-28M | · |
Rentabilité 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -60.3% | -67.0% | -57.5% | -33.2% | -25.5% | · | |
| ROE | -47.7% | -233.8% | -64.2% | -38.8% | -13.0% | · | |
| ROIC | -34.2% | -97.7% | -74.4% | -42.0% | -13.4% | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 21.1 | 20.9 | 7.0 | 16.9 | 68.4 | · | |
| Quick Ratio | 20.3 | 20.5 | 6.9 | 16.6 | 65.6 | · |
Valorisation (TTM) 8
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-127M | $-70M | $-76M | $-52M | $-23M | · | |
| Market Cap | $761M | $2.69B | $21.99B | $25.35B | $10.07B | · | |
| P/E | -4.8 | -38.0 | -276.0 | -488.3 | -220.7 | · | |
| P/B | 2.3 | 35.2 | 200.9 | 200.0 | 58.4 | · | |
| P / Tangible Book | 2.3 | · | 200.9 | 200.0 | 58.4 | · | |
| P / Cash Flow | -8.0 | -37.8 | -387.3 | -648.1 | -367.6 | · | |
| P / FCF | -8.0 | · | -386.3 | -644.8 | -365.2 | · | |
| Earnings Yield | -20.7% | -2.6% | -0.36% | -0.20% | -0.45% | · |
Compte de résultat 13
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $50M | $36M | $29M | $22M | $23M | $20M | $-2M | $14M | $21M | $20M | $18M | $17M | $16M | $13M | $12M | $11M | |
| SG&A Expense | $9M | $7M | $6M | $5M | $5M | $3M | $11M | $1M | $5M | $5M | $4M | $4M | $4M | $4M | $4M | $3M | |
| Operating Expenses | $59M | $43M | $55M | $27M | $28M | $23M | $9M | $15M | $26M | $25M | $22M | $21M | $20M | $18M | $16M | $14M | |
| Operating Income | $-59M | $-43M | $-55M | $-27M | $-28M | $-23M | $-9M | $-15M | $-26M | $-25M | $-22M | $-21M | $-20M | $-18M | $-16M | $-14M | |
| Other Non-op | $-62.0K | $-9.0K | $4M | $-28.0K | $0 | $0 | $-1M | $0 | $1M | $-3.0K | $-2M | $1.0K | $1M | $1M | $2M | $4.0K | |
| Pretax Income | $-56M | $-40M | · | · | $-32M | $-38M | · | · | · | · | · | · | · | · | · | · | |
| Income Tax | $15.0K | $16.0K | $58.0K | $0 | $0 | · | · | $0 | · | · | · | · | · | · | · | · | |
| Net Income | $-56M | $-40M | $-32M | $-25M | $-32M | $-38M | $-5M | $-16M | $-25M | $-23M | $-20M | $-20M | $-19M | $-17M | $-15M | $-14M | |
| EPS (Basic) | $-0.76 | $-0.57 | $-1.76 | $-0.48 | $-0.86 | $-12.10 | $4.41 | $-5.16 | $-0.86 | $-0.83 | $-0.73 | $-0.71 | $-0.76 | $-0.67 | $-0.60 | $-0.56 | |
| EPS (Diluted) | $-0.76 | $-0.57 | $-1.76 | $-0.48 | $-0.86 | $-12.10 | $4.41 | $-5.16 | $-0.86 | $-0.83 | $-0.73 | $-0.71 | $-0.76 | $-0.67 | $-0.60 | $-0.56 | |
| Shares (Basic) | 61,050,775 | 57,777,165 | -65,640,708 | 39,584,489 | 28,431,158 | 3,155,500 | -31,125,176 | 3,155,500 | 28,756,043 | 27,795,827 | -51,253,264 | 27,640,542 | 25,166,505 | 24,777,847 | -48,803,578 | 24,454,786 | |
| Shares (Diluted) | 61,050,775 | 57,777,165 | -65,640,708 | 39,584,489 | 28,431,158 | 3,155,500 | -31,125,176 | 3,155,500 | 28,756,043 | 27,795,827 | -51,253,264 | 27,640,542 | 25,166,505 | 24,777,847 | -48,803,578 | 24,454,786 | |
| EBITDA | $-59M | $-43M | · | $-27M | $-28M | $-3M | · | $-17M | $-26M | $-25M | · | $-21M | $-20M | $-18M | · | $-14M |
Bilan 19
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $107M | $55M | $88M | $50M | $221M | $44M | $34M | $31M | $31M | $9M | $23M | $32M | $61M | $27M | $22M | $22M | |
| Short-term Investments | $354M | $256M | $248M | $149M | · | $32M | $45M | $58M | $73M | $90M | $99M | $103M | $89M | $92M | $107M | $120M | |
| Prepaid Expense | $10M | $7M | $13M | $2M | $2M | $1M | $1M | $2M | $7M | $4M | $2M | $2M | $2M | $2M | $2M | $3M | |
| Current Assets | $471M | $319M | $349M | $201M | $223M | $77M | $80M | $91M | $111M | $103M | $124M | $138M | $152M | $121M | $131M | $145M | |
| PP&E (Net) | $144.0K | $157.0K | $170.0K | $176.0K | $147.0K | $2.0K | $6.0K | $14.0K | $232.0K | $260.0K | $288.0K | $316.0K | $245.0K | $267.0K | $242.0K | $330.0K | |
| Other Non-current Assets | $69.0K | $69.0K | $69.0K | $174.0K | $60.0K | · | · | $81.0K | $81.0K | $3M | $2M | $2M | $2M | $3M | $3M | $1M | |
| Total Assets | $472M | $319M | $350M | $202M | $224M | $78M | $80M | $91M | $112M | $107M | $127M | $141M | $156M | $124M | $135M | $148M | |
| Accounts Payable | $7M | $4M | $2M | $1M | $8M | $69.0K | $224.0K | $908.0K | $4M | $3M | $2M | $4M | $6M | $5M | $3M | $5M | |
| Accrued Liabilities | $15M | $15M | $9M | $14M | $8M | · | · | · | · | · | · | · | · | · | · | · | |
| Current Liabilities | $32M | $22M | $17M | $22M | $22M | $2M | $4M | $10M | $17M | $16M | $18M | $15M | $13M | $11M | $8M | $8M | |
| Capital Leases | $628.0K | $679.0K | $724.0K | $747.0K | $792.0K | · | · | $81.0K | $206.0K | $329.0K | $255.0K | $358.0K | $476.0K | $591.0K | $705.0K | $800.0K | |
| Total Liabilities | $32M | $23M | $17M | $23M | $22M | $2M | $4M | $10M | $17M | $16M | $18M | $15M | $14M | $11M | $9M | $9M | |
| Common Stock | $6.0K | $5.0K | $5.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $2.0K | $2.0K | $2.0K | |
| Paid-in Capital | $711M | $512M | $507M | $322M | $319M | $311M | $309M | $308M | $306M | $278M | $273M | $269M | $266M | $218M | $215M | $213M | |
| Retained Earnings | $-271M | $-215M | $-174M | $-142M | $-117M | $-236M | $-233M | $-228M | $-211M | $-187M | $-163M | $-143M | $-123M | $-104M | $-88M | $-73M | |
| AOCI | $-660.0K | $-342.0K | $129.0K | $29.0K | $-24.0K | $50.0K | $105.0K | $224.0K | $-83.0K | $-33.0K | $237.0K | $-195.0K | $-223.0K | $-201.0K | $-466.0K | $-771.0K | |
| Stockholders' Equity | $440M | $296M | $333M | $179M | $202M | $75M | $76M | $80M | $94M | $91M | $109M | $126M | $142M | $113M | $127M | $139M | |
| Liabilities + Equity | $472M | $319M | $350M | $202M | $224M | $78M | $80M | $91M | $112M | $107M | $127M | $141M | $156M | $124M | $135M | $148M | |
| Shares Outstanding | 63,556,065 | 49,345,967 | 49,316,287 | 32,626,730 | 32,626,730 | 28,985,019 | 28,985,019 | 28,867,711 | 28,854,750 | 27,898,761 | 27,762,703 | 27,653,187 | 27,601,098 | 24,816,940 | 24,722,974 | 24,506,390 |
Flux de trésorerie 8
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $14M | $7M | $11M | $4M | $4M | $2M | $3M | $27.0K | $4M | $4M | $3M | $3M | $3M | $2M | $2M | $1M | |
| Operating Cash Flow | $-44M | $-24M | $-34M | $-22M | $-37M | $-19M | $-11M | $-7M | $-20M | $-24M | $-15M | $-16M | $-15M | $-11M | $-15M | $-10M | |
| CapEx | · | · | $3.0K | $57.0K | · | · | · | · | · | · | $64.0K | $32.0K | $30.0K | $16.0K | $4.0K | $33.0K | |
| Investing Cash Flow | $-98M | $-8M | $-98M | $-149M | $-13M | $13M | $13M | $0 | $18M | $9M | $6M | $-13M | $4M | $15M | $14M | $5M | |
| Stock Issued | · | · | · | · | · | · | $307.0K | $0 | · | · | $0 | $0 | · | · | · | · | |
| Financing Cash Flow | $194M | $-795.0K | $170M | $0 | $191M | $-700.0K | $554.0K | $95M | $24M | $471.0K | $463.0K | $20.0K | $45M | $223.0K | $357.0K | $37.0K | |
| Net Change in Cash | $52M | $-33M | $38M | $-171M | $141M | $-19M | $3M | $88M | $22M | $-14M | $-9M | $-29M | $34M | $4M | $-22.0K | $-5M | |
| Free Cash Flow | · | · | · | · | · | · | · | · | · | · | · | · | · | $-11M | · | · |
Rentabilité 3
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -16.0% | -20.3% | · | -17.2% | -19.1% | -2.7% | · | -14.0% | -18.5% | -20.1% | · | -13.6% | -12.2% | -11.3% | · | -8.2% | |
| ROE | -17.4% | -21.7% | · | -19.4% | -21.7% | -3.0% | · | -15.8% | -21.0% | -22.7% | · | -14.8% | -13.0% | -12.0% | · | -8.5% | |
| ROIC | -13.4% | -14.7% | · | · | · | · | · | · | · | · | · | · | · | · | · | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.9 | 14.3 | · | 9.0 | 10.3 | 32.0 | · | 8.8 | 6.5 | 6.7 | · | 9.3 | 11.5 | 11.3 | · | 18.8 | |
| Quick Ratio | 14.6 | 14.0 | · | 8.9 | 10.2 | 31.5 | · | 8.6 | 6.1 | 6.4 | · | 9.2 | 11.3 | 11.2 | · | 18.5 |
Valorisation (TTM) 8
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-153M | $-136M | · | $-112M | $-111M | $-102M | · | $-84M | $-87M | $-78M | · | $-69M | $-61M | $-53M | · | $-43M | |
| Market Cap | $1.41B | $693M | · | $282M | $326M | $2.55B | · | $2.11B | $1.68B | $28.87B | · | $13.13B | $16.57B | $17.52B | · | $14.22B | |
| P/E | -8.3 | -1.0 | · | -1.3 | -1.4 | -12.7 | · | -9.7 | -18.4 | -348.5 | · | -175.9 | -242.0 | -325.3 | · | -329.7 | |
| P/B | 3.2 | 2.3 | · | 1.6 | 1.6 | 33.9 | · | 26.2 | 17.8 | 317.6 | · | 104.5 | 116.7 | 154.9 | · | 102.2 | |
| P / Tangible Book | 3.2 | 2.3 | · | 1.6 | 1.6 | 33.9 | · | 26.2 | 17.8 | 317.6 | · | 104.5 | 116.7 | 154.9 | · | 102.2 | |
| P / Cash Flow | · | -28.8 | · | · | · | -1069.4 | · | · | · | -1219.7 | · | · | · | -1533.6 | · | · | |
| P / FCF | · | · | · | · | · | · | · | · | · | · | · | · | · | -1531.4 | · | · | |
| Earnings Yield | -12.0% | -99.7% | · | -76.4% | -69.8% | -7.9% | · | -10.3% | -5.4% | -0.29% | · | -0.57% | -0.41% | -0.31% | · | -0.30% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Résultat net | $-127M | $-70M | $-76M | $-52M | $-23M |
| BPA dilué | $-3.19 | $-2.44 | $-2.87 | $-2.10 | $-1.87 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 21.1 | 20.9 | 7.0 | 16.9 | 68.4 |
| Ratio de liquidité réduite | 20.3 | 20.5 | 6.9 | 16.6 | 65.6 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-95M | — | $-57M | $-39M | $-28M |
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Détenteurs institutionnels (13F) 161 déclarants · $1.3B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
Activité institutionnelle — Q2 2026 vs trimestre précédent
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 58 (+24 vs T. préc.) | 16 (+5 vs T. préc.) | 52 (+16 vs T. préc.) | 26 (-3 vs T. préc.) | +10.7M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| FMR LLC | $160 922 573 | 7 242 240 | 12,56% | Actions |
| Fairmount Funds Management LLC | $101 178 637 | 4 553 494 | 7,90% | Actions |
| RA CAPITAL MANAGEMENT, L.P. | $81 571 464 | 3 671 083 | 6,37% | Actions |
| Venrock Adviser, LLC | $71 556 488 | 3 220 364 | 5,59% | Actions |
| Bellevue Group AG | $67 948 671 | 3 057 996 | 5,31% | Actions |
| Paradigm Biocapital Advisors LP | $63 491 539 | 2 857 405 | 4,96% | Actions |
| STATE STREET CORP | $51 890 033 | 2 335 285 | 4,05% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $49 878 856 | 2 244 773 | 3,89% | Actions |
| JANUS HENDERSON GROUP PLC | $43 557 008 | 3 105 669 | 3,40% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $42 458 243 | 1 910 812 | 3,31% | Actions |
| Polar Capital Holdings Plc | $41 039 940 | 1 846 982 | 3,20% | Actions |
| Avidity Partners Management LP | $37 789 732 | 1 700 708 | 2,95% | Actions |
| Remedium Capital Partners, LLC | $35 057 605 | 1 577 750 | 2,74% | Actions |
| Soleus Capital Management, L.P. | $34 456 332 | 1 550 690 | 2,69% | Actions |
| BAKER BROS. ADVISORS LP | $27 340 066 | 1 230 426 | 2,13% | Actions |
| Logos Global Management LP | $24 997 500 | 1 125 000 | 1,95% | Actions |
| Versant Venture Management, LLC | $22 037 418 | 991 783 | 1,72% | Actions |
| ACORN CAPITAL ADVISORS, LLC | $21 925 807 | 986 760 | 1,71% | Actions |
| Foresite Capital Management VI LLC | $19 701 741 | 886 667 | 1,54% | Actions |
| Balyasny Asset Management L.P. | $19 525 292 | 878 726 | 1,52% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $18 744 951 | 843 337 | 1,46% | Actions |
| Affinity Asset Advisors, LLC | $18 672 577 | 840 350 | 1,46% | Actions |
| SAMSARA BIOCAPITAL, LLC | $16 359 186 | 736 237 | 1,28% | Actions |
| Pictet Asset Management Holding SA | $16 304 325 | 733 768 | 1,27% | Actions |
| Aberdeen Group plc | $13 801 020 | 621 108 | 1,08% | Actions |
| GOLDMAN SACHS GROUP INC | $13 387 928 | 602 517 | 1,05% | Actions |
| MARSHALL WACE, LLP | $12 342 966 | 555 489 | 0,96% | Actions |
| CITADEL ADVISORS LLC | $12 093 546 | 544 264 | 0,94% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $10 255 152 | 461 528 | 0,80% | Actions |
| BANK OF AMERICA CORP /DE/ | $10 088 569 | 454 031 | 0,79% | Actions |
| Blackstone Inc. | $9 672 810 | 435 320 | 0,76% | Actions |
| Ikarian Capital, LLC | $9 495 694 | 427 349 | 0,74% | Actions |
| Walleye Capital LLC | $8 116 344 | 365 272 | 0,63% | Actions |
| MILLENNIUM MANAGEMENT LLC | $6 989 257 | 314 548 | 0,55% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $6 774 145 | 304 867 | 0,53% | Actions |
| Connor, Clark & Lunn Investment Management Ltd. | $4 825 229 | 217 157 | 0,38% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $4 431 312 | 199 429 | 0,35% | Actions |
| Point72 Asset Management, L.P. | $3 715 273 | 167 204 | 0,29% | Actions |
| Opaleye Management Inc. | $3 221 900 | 145 000 | 0,25% | Actions |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $3 114 989 | 140 886 | 0,24% | Actions |
| Quantinno Capital Management LP | $2 548 990 | 114 716 | 0,20% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $2 504 261 | 112 703 | 0,20% | Actions |
| VANGUARD GROUP INC | $2 491 621 | 161 479 | 0,19% | Actions |
| Sofinnova Investments, Inc. | $2 386 228 | 107 391 | 0,19% | Actions |
| AMERIPRISE FINANCIAL INC | $2 378 718 | 107 053 | 0,19% | Actions |
| Woodline Partners LP | $2 227 977 | 100 269 | 0,17% | Actions |
| SEVEN GRAND MANAGERS, LLC | $2 222 000 | 100 000 | 0,17% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2 221 489 | 99 977 | 0,17% | Actions |
| Atle Fund Management AB | $1 967 714 | 88 556 | 0,15% | Actions |
| Swiss National Bank | $1 850 926 | 83 300 | 0,14% | Actions |
| RAYMOND JAMES FINANCIAL INC | $1 749 225 | 78 723 | 0,14% | Actions |
| Longaeva Partners L.P. | $1 744 292 | 78 501 | 0,14% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $1 635 192 | 73 591 | 0,13% | Actions |
| AMERICAN CENTURY COMPANIES INC | $1 532 736 | 68 980 | 0,12% | Actions |
| Trexquant Investment LP | $1 517 982 | 68 316 | 0,12% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 517 626 | 68 300 | 0,12% | Option de vente |
| Harvest Investment Services, LLC | $1 399 482 | 62 983 | 0,11% | Actions |
| Corient Private Wealth LP | $1 365 199 | 61 440 | 0,11% | Actions |
| XTX Topco Ltd | $1 313 046 | 59 093 | 0,10% | Actions |
| Verdad Advisers, LP | $1 252 852 | 56 384 | 0,10% | Actions |
| Squarepoint Ops LLC | $1 210 012 | 54 456 | 0,09% | Actions |
| CITIGROUP INC | $1 166 506 | 52 498 | 0,09% | Actions |
| Maven Securities LTD | $1 111 000 | 50 000 | 0,09% | Actions |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $1 074 870 | 48 374 | 0,08% | Actions |
| TWO SIGMA INVESTMENTS, LP | $1 007 921 | 45 361 | 0,08% | Actions |
| Rafferty Asset Management, LLC | $947 216 | 42 629 | 0,07% | Actions |
| RHUMBLINE ADVISERS | $908 965 | 40 908 | 0,07% | Actions |
| Russell Investments Group, Ltd. | $869 734 | 39 141 | 0,07% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $812 963 | 36 587 | 0,06% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $797 698 | 35 900 | 0,06% | Option d'achat |
| Vanguard Global Advisers, LLC | $757 546 | 34 093 | 0,06% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $702 441 | 31 613 | 0,05% | Actions |
| BlackRock, Inc. | $673 999 | 30 333 | 0,05% | Actions |
| ALLIANCEBERNSTEIN L.P. | $664 987 | 47 330 | 0,05% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $635 003 | 28 578 | 0,05% | Actions |
| Voleon Capital Management LP | $617 205 | 27 777 | 0,05% | Actions |
| Man Group plc | $580 453 | 26 123 | 0,05% | Actions |
| D. E. Shaw & Co., Inc. | $526 614 | 23 700 | 0,04% | Actions |
| Engineers Gate Manager LP | $502 594 | 22 619 | 0,04% | Actions |
| Aquatic Capital Management LLC | $498 417 | 22 431 | 0,04% | Actions |
| BARCLAYS PLC | $485 285 | 21 840 | 0,04% | Actions |
| PROFUND ADVISORS LLC | $475 775 | 21 412 | 0,04% | Actions |
| Virtus Investment Advisers, LLC | $473 930 | 21 329 | 0,04% | Actions |
| Bank of New York Mellon Corp | $454 221 | 20 442 | 0,04% | Actions |
| Ghisallo Capital Management LLC | $444 400 | 20 000 | 0,03% | Actions |
| MetLife Investment Management, LLC | $438 601 | 19 739 | 0,03% | Actions |
| KLP KAPITALFORVALTNING AS | $306 636 | 13 800 | 0,02% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $292 037 | 13 143 | 0,02% | Actions |
| Invesco Ltd. | $284 327 | 12 796 | 0,02% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $256 019 | 11 522 | 0,02% | Actions |
| State of New Jersey Common Pension Fund D | $221 445 | 9 966 | 0,02% | Actions |
| Brevan Howard Capital Management LP | $215 623 | 9 704 | 0,02% | Actions |
| DELTEC ASSET MANAGEMENT LLC | $209 668 | 9 436 | 0,02% | Actions |
| Police & Firemen's Retirement System of New Jersey | $204 824 | 9 218 | 0,02% | Actions |
| UBS Group AG | $194 936 | 8 773 | 0,02% | Actions |
| Vanguard Investments Australia, Ltd. | $173 916 | 7 827 | 0,01% | Actions |
| Nuveen, LLC | $136 742 | 6 154 | 0,01% | Actions |
| NORTHERN TRUST CORP | $113 633 | 5 114 | 0,01% | Actions |
| MERCER GLOBAL ADVISORS INC /ADV | $109 545 | 4 930 | 0,01% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $109 489 | 4 952 | 0,01% | Actions |
Initiés de la société 20 initiés · 4 dirigeants · 9 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Tom Frohlich | Chief Executive Officer | 12 février 2026 A | 86 331 | 0 | 0 | $0 |
| Bradford D. Dahms | Chief Financial Officer | 12 février 2026 A | 37 813 | 0 | 0 | $0 |
| Elizabeth Balta | Chief Legal Officer and Corporate Secretary | 12 février 2026 A | 28 125 | 0 | 0 | $0 |
| Andrew James King | Chief Scientific Officer & Head of Research and Development | 12 février 2026 A | 386 113 | 0 | 0 | $0 |
| Mark Eisner | Administrateur | 25 juin 2026 A | — | 0 | 0 | $0 |
| Christopher W. Cain | Administrateur | 9 juin 2026 A | — | 0 | 0 | $0 |
| Lawrence Otto Klein | Administrateur | 9 juin 2026 A | — | 0 | 0 | $0 |
| Erin Lavelle | Administrateur | 9 juin 2026 A | — | 0 | 0 | $0 |
| Eric Dobmeier | Administrateur | 9 juin 2026 A | — | 0 | 0 | $0 |
| Allison Dorval | Administrateur | 15 juillet 2021 A | — | 0 | 0 | $0 |
| David S. Grayzel | Administrateur | 2 juillet 2021 C | 3 103 879 | 0 | 0 | $0 |
| Dr. Maha Katabi | Administrateur | 2 juillet 2021 C | 3 758 686 | 0 | 0 | $0 |
| Atlas Venture Fund XII, L.P. | Détenteur de 10% | 15 juillet 2022 J | 2 327 909 | 0 | 0 | $0 |
| Benjamin T Dake | — | 29 juin 2021 A | — | 0 | 0 | $0 |
| Hunter Gillies | — | 29 juin 2021 A | — | 0 | 0 | $0 |
| Joshua Resnick | — | 29 juin 2021 A | — | 0 | 0 | $0 |
| Mark T Iwicki | — | 29 juin 2021 A | — | 0 | 0 | $0 |
| George A Eldridge | — | 29 juin 2021 A | — | 0 | 0 | $0 |
| Timothy P Noyes | — | 29 juin 2021 A | — | 0 | 0 | $0 |
| Ralph Niven | — | 29 juin 2021 A | — | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 5 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| Fairmount Funds Management LLC, Fairmount Healthcare Fund II L.P., Fairmount Healthcare Co-Invest IV L.P., Peter Evan Harwin, Tomas Kiselak ×3 dépôts | 9 juin 2026 | 19,99% | Amendement | — | SEC |
| Sofinnova Venture Partners X, L.P. ("SVP X"), Sofinnova Management X, L.P. ("SM X LP"), Sofinnova Management X-A, L.L.C. ("SM X LLC"), Dr. James I. Healy ("Healy"), Dr. Maha Katabi ("Katabi") | 5 mars 2026 | 0,30% | Amendement | Investissement passif | SEC |
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×5 dépôts | 30 avril 2025 | 4,10% | Amendement | — | SEC |
| Atlas Venture Fund XII, L.P., Atlas Venture Associates XII, L.P., Atlas Venture Associates XII, LLC ×5 dépôts | 30 avril 2025 | 0,20% | Amendement | Fusions et acquisitions / vente | SEC |
| Sofinnova Venture Partners X, L.P. (“SVP X”), Sofinnova Management X, L.P. (“SM X LP”), Sofinnova Management X-A, L.L.C. (“SM X LLC”), Dr. James I. Healy (“Healy”), Dr. Maha Katabi (“Katabi”) ×3 dépôts | 20 février 2024 | — | Dépôt initial | Investissement passif | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 24 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 1,20% | 18 425 NS | 30 avril 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,17% | 90 180 NS | 30 avril 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,04% | 53 058 NS | 31 mai 2026 | N-PORT |
| ITWO · ProShares Trust | 0,02% | 1 500 NS | 31 mai 2026 | N-PORT |
| UWM · ProShares Trust | 0,01% | 1 173 NS | 31 mai 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 3 435 NS | 31 mai 2026 | N-PORT |
| URTY · ProShares Trust | 0,01% | 1 189 NS | 31 mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 25 716 NS | 31 mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 30 NS | 31 mai 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 5 087 NS | 31 mai 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTI · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VFMO · VANGUARD WELLINGTON FUND | — | — | 30 juillet 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTWG · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| ITOT · iShares Trust | — | — | 22 juillet 2026 | Quotidien |
| IWV · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IWO · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IWM · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IWC · iShares Trust | — | — | 18 août 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | — | — | 20 juillet 2026 | Quotidien |
| ISCB · iShares Trust | — | — | 20 juillet 2026 | Quotidien |
| WSML · iShares Trust | — | — | 20 juillet 2026 | Quotidien |