RAPP — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| FMR LLC | $298 894 493 | 7 172 894 | 13,99% | Actions |
| TRV GP V, LLC | $261 709 477 | 6 280 525 | 12,25% | Actions |
| ARCH Venture Management, LLC | $155 376 512 | 3 728 738 | 7,27% | Actions |
| Capital International Investors | $121 757 990 | 2 921 958 | 5,70% | Actions |
| GOLDMAN SACHS GROUP INC | $121 278 410 | 2 910 449 | 5,68% | Actions |
| BlackRock, Inc. | $112 500 083 | 2 699 786 | 5,27% | Actions |
| Cormorant Asset Management, LP | $110 738 900 | 2 657 521 | 5,18% | Actions |
| Sofinnova Investments, Inc. | $79 356 681 | 1 904 408 | 3,71% | Actions |
| JOHNSON & JOHNSON | $74 360 823 | 1 784 517 | 3,48% | Actions |
| Polar Capital Holdings Plc | $67 026 778 | 1 608 514 | 3,14% | Actions |
| BAKER BROS. ADVISORS LP | $64 467 240 | 1 547 090 | 3,02% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $56 109 155 | 1 346 512 | 2,63% | Actions |
| VANGUARD GROUP INC | $55 150 747 | 1 817 757 | 2,58% | Actions |
| TRV GP VI, LLC | $40 387 314 | 969 218 | 1,89% | Actions |
| STATE STREET CORP | $34 115 729 | 818 712 | 1,60% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $33 068 458 | 793 453 | 1,55% | Actions |
| PERCEPTIVE ADVISORS LLC | $32 225 161 | 773 342 | 1,51% | Actions |
| Vestal Point Capital, LP | $30 419 100 | 730 000 | 1,42% | Actions |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $28 751 317 | 918 866 | 1,35% | Actions |
| Siren, L.L.C. | $26 730 013 | 641 469 | 1,25% | Actions |
| Capital World Investors | $22 987 547 | 551 657 | 1,08% | Actions |
| ALLIANCEBERNSTEIN L.P. | $21 695 985 | 693 384 | 1,02% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $15 087 064 | 362 114 | 0,71% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $14 998 866 | 359 944 | 0,70% | Actions |
| Candriam S.C.A. | $14 472 638 | 347 650 | 0,68% | Actions |
| Sio Capital Management, LLC | $12 820 067 | 307 657 | 0,60% | Actions |
| MORGAN STANLEY | $12 401 492 | 297 612 | 0,58% | Actions |
| NORTHERN TRUST CORP | $11 555 299 | 277 305 | 0,54% | Actions |
| KENNEDY CAPITAL MANAGEMENT LLC | $10 450 628 | 250 795 | 0,49% | Actions |
| Burkehill Global Management, LP | $10 417 500 | 250 000 | 0,49% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $10 284 781 | 246 815 | 0,48% | Actions |
| ALGERT GLOBAL LLC | $9 326 663 | 223 822 | 0,44% | Actions |
| Invesco Ltd. | $8 968 884 | 215 236 | 0,42% | Actions |
| D. E. Shaw & Co., Inc. | $8 952 008 | 214 831 | 0,42% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $8 681 236 | 208 333 | 0,41% | Actions |
| Ensign Peak Advisors, Inc | $6 898 302 | 165 546 | 0,32% | Actions |
| MILLENNIUM MANAGEMENT LLC | $6 455 016 | 154 908 | 0,30% | Actions |
| UBS Group AG | $6 299 420 | 151 174 | 0,29% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $6 250 500 | 150 000 | 0,29% | Actions |
| Artia Global Partners LP | $5 771 628 | 138 508 | 0,27% | Actions |
| Swedbank AB | $4 892 058 | 117 400 | 0,23% | Actions |
| Nuveen, LLC | $4 307 053 | 103 361 | 0,20% | Actions |
| Walleye Capital LLC | $4 257 132 | 102 163 | 0,20% | Actions |
| Woodline Partners LP | $4 064 367 | 97 537 | 0,19% | Actions |
| TD Asset Management Inc | $3 828 556 | 91 878 | 0,18% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $3 624 790 | 86 988 | 0,17% | Actions |
| PRUDENTIAL FINANCIAL INC | $3 620 498 | 86 885 | 0,17% | Actions |
| CITADEL ADVISORS LLC | $3 435 358 | 82 442 | 0,16% | Actions |
| Bank of New York Mellon Corp | $3 426 191 | 82 222 | 0,16% | Actions |
| ORBIMED ADVISORS LLC | $3 192 589 | 76 616 | 0,15% | Actions |
| BANK OF AMERICA CORP /DE/ | $3 170 087 | 76 076 | 0,15% | Actions |
| DAFNA Capital Management LLC | $3 125 250 | 75 000 | 0,15% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2 903 649 | 69 682 | 0,14% | Actions |
| STEMPOINT CAPITAL LP | $2 774 472 | 66 582 | 0,13% | Actions |
| AMERICAN CENTURY COMPANIES INC | $2 740 386 | 65 764 | 0,13% | Actions |
| XTX Topco Ltd | $2 560 246 | 61 441 | 0,12% | Actions |
| VOYA INVESTMENT MANAGEMENT LLC | $2 439 237 | 58 537 | 0,11% | Actions |
| Allspring Global Investments Holdings, LLC | $2 394 692 | 57 468 | 0,11% | Actions |
| JANE STREET GROUP, LLC | $2 321 228 | 55 705 | 0,11% | Actions |
| Russell Investments Group, Ltd. | $2 310 936 | 55 458 | 0,11% | Actions |
| Swiss National Bank | $2 300 184 | 55 200 | 0,11% | Actions |
| Trexquant Investment LP | $2 247 555 | 53 937 | 0,11% | Actions |
| ALPS ADVISORS INC | $2 010 286 | 48 243 | 0,09% | Actions |
| Susquehanna Portfolio Strategies, LLC | $1 665 883 | 39 978 | 0,08% | Actions |
| RHUMBLINE ADVISERS | $1 550 030 | 37 198 | 0,07% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1 354 233 | 32 499 | 0,06% | Actions |
| DEUTSCHE BANK AG\ | $1 342 274 | 32 212 | 0,06% | Actions |
| WELLS FARGO & COMPANY/MN | $1 340 566 | 32 171 | 0,06% | Actions |
| Integrated Quantitative Investments LLC | $1 266 185 | 30 386 | 0,06% | Actions |
| AQR CAPITAL MANAGEMENT LLC | $1 102 338 | 26 454 | 0,05% | Actions |
| TWO SIGMA INVESTMENTS, LP | $1 019 665 | 24 470 | 0,05% | Actions |
| CITIGROUP INC | $1 015 623 | 24 373 | 0,05% | Actions |
| Ellsworth Advisors, LLC | $979 842 | 24 539 | 0,05% | Actions |
| Creative Planning | $954 993 | 22 918 | 0,04% | Actions |
| Legal & General Group Plc | $939 867 | 22 555 | 0,04% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $920 949 | 22 101 | 0,04% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $919 032 | 22 055 | 0,04% | Actions |
| Engineers Gate Manager LP | $888 154 | 21 314 | 0,04% | Actions |
| Y-Intercept (Hong Kong) Ltd | $799 606 | 19 189 | 0,04% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $772 228 | 18 532 | 0,04% | Actions |
| MetLife Investment Management, LLC | $750 435 | 18 009 | 0,04% | Actions |
| Vanguard Global Advisers, LLC | $718 391 | 17 240 | 0,03% | Actions |
| SEI INVESTMENTS CO | $678 971 | 16 294 | 0,03% | Actions |
| JPMORGAN CHASE & CO | $669 021 | 16 564 | 0,03% | Actions |
| BARCLAYS PLC | $624 800 | 14 994 | 0,03% | Actions |
| AMERIPRISE FINANCIAL INC | $612 382 | 14 696 | 0,03% | Actions |
| OPTIMIZE FINANCIAL INC. | $608 632 | 14 606 | 0,03% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $594 048 | 14 256 | 0,03% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $587 880 | 14 108 | 0,03% | Actions |
| PSP Research LLC | $583 380 | 14 000 | 0,03% | Actions |
| VARCOV Co. | $537 335 | 12 895 | 0,03% | Actions |
| China Universal Asset Management Co., Ltd. | $450 536 | 10 812 | 0,02% | Actions |
| Allianz Asset Management GmbH | $445 869 | 10 700 | 0,02% | Actions |
| JANUS HENDERSON GROUP PLC | $432 768 | 13 800 | 0,02% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $429 201 | 10 300 | 0,02% | Actions |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $424 034 | 10 176 | 0,02% | Actions |
| CATALYST PRIVATE WEALTH, LLC | $416 700 | 10 000 | 0,02% | Actions |
| STIFEL FINANCIAL CORP | $407 243 | 9 773 | 0,02% | Actions |
| CLEAR WAVE WEALTH MANAGEMENT LLC | $395 865 | 9 500 | 0,02% | Actions |
| Police & Firemen's Retirement System of New Jersey | $376 447 | 9 034 | 0,02% | Actions |
| State of New Jersey Common Pension Fund D | $370 321 | 8 887 | 0,02% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $362 529 | 8 700 | 0,02% | Option d'achat |
| Virtus Investment Advisers, LLC | $355 070 | 8 521 | 0,02% | Actions |
| INTECH INVESTMENT MANAGEMENT LLC | $348 820 | 8 371 | 0,02% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $343 986 | 8 255 | 0,02% | Actions |
| ARIZONA STATE RETIREMENT SYSTEM | $316 025 | 7 584 | 0,01% | Actions |
| Vanguard Investments Australia, Ltd. | $302 483 | 7 259 | 0,01% | Actions |
| AlphaCentric Advisors LLC | $272 147 | 6 531 | 0,01% | Actions |
| Quadrature Capital Ltd | $264 980 | 6 359 | 0,01% | Actions |
| PROFUND ADVISORS LLC | $264 938 | 6 358 | 0,01% | Actions |
| KLP KAPITALFORVALTNING AS | $245 853 | 5 900 | 0,01% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $241 686 | 5 800 | 0,01% | Option de vente |
| ProShare Advisors LLC | $232 519 | 5 580 | 0,01% | Actions |
| Pictet Asset Management Holding SA | $216 601 | 5 198 | 0,01% | Actions |
| JANE STREET GROUP, LLC | $208 350 | 5 000 | 0,01% | Option de vente |
| Sandia Investment Management LP | $182 040 | 6 000 | 0,01% | Actions |
| Tower Research Capital LLC (TRC) | $124 010 | 2 976 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $115 843 | 2 780 | 0,01% | Actions |
| MEEDER ASSET MANAGEMENT INC | $115 593 | 2 774 | 0,01% | Actions |
| AlphaQuest LLC | $113 896 | 3 754 | 0,01% | Actions |
| STRS OHIO | $108 342 | 2 600 | 0,01% | Actions |
| Mirae Asset Global Investments Co., Ltd. | $89 132 | 2 139 | 0,00% | Actions |
| Aquatic Capital Management LLC | $88 007 | 2 112 | 0,00% | Actions |
| NISA INVESTMENT ADVISORS, LLC | $79 923 | 1 918 | 0,00% | Actions |
| State of Wyoming | $65 005 | 1 560 | 0,00% | Actions |
| ROYAL BANK OF CANADA | $47 000 | 1 147 | 0,00% | Actions |
| CWM, LLC | $46 153 | 1 475 | 0,00% | Actions |
| Tidemark, LLC | $45 337 | 1 088 | 0,00% | Actions |
| GF FUND MANAGEMENT CO. LTD. | $42 128 | 1 011 | 0,00% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $32 814 | 787 446 | 0,00% | Actions |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $32 128 | 771 | 0,00% | Actions |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $20 710 | 497 | 0,00% | Actions |
| GAMMA Investing LLC | $17 001 | 408 | 0,00% | Actions |
| T. Rowe Price Investment Management, Inc. | $16 385 | 393 200 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $15 668 | 376 | 0,00% | Actions |
| FEDERATED HERMES, INC. | $10 001 | 240 | 0,00% | Actions |
| Stone House Investment Management, LLC | $8 792 | 211 | 0,00% | Actions |
| SIGNATUREFD, LLC | $8 542 | 205 | 0,00% | Actions |
| MassMutual Private Wealth & Trust, FSB | $6 792 | 163 | 0,00% | Actions |
| EverSource Wealth Advisors, LLC | $6 125 | 147 | 0,00% | Actions |
| Sterling Capital Management LLC | $5 875 | 141 | 0,00% | Actions |
| Larson Financial Group LLC | $5 459 | 131 | 0,00% | Actions |
| OSAIC HOLDINGS, INC. | $5 167 | 124 | 0,00% | Actions |
| TD Waterhouse Canada Inc. | $4 845 | 123 | 0,00% | Actions |
| Aster Capital Management (DIFC) Ltd | $4 500 | 108 | 0,00% | Actions |
| Arax Advisory Partners | $2 251 | 54 | 0,00% | Actions |
| Optiver Holding B.V. | $2 250 | 54 | 0,00% | Actions |
| SBI Securities Co., Ltd. | $2 209 | 53 | 0,00% | Actions |
| Cornerstone Financial Management LLC | $2 042 | 49 | 0,00% | Actions |
| PNC Financial Services Group, Inc. | $2 000 | 48 | 0,00% | Actions |
| True Wealth Design, LLC | $1 709 | 41 | 0,00% | Actions |
| Essential Partners LLC | $1 667 | 40 | 0,00% | Actions |
| Bare Financial Services, Inc | $1 625 | 39 | 0,00% | Actions |
| Versant Capital Management, Inc | $907 | 27 | 0,00% | Actions |
| Silver Grove Financial Group, Inc. | $875 | 21 | 0,00% | Actions |
| ROTHSCHILD INVESTMENT LLC | $833 | 20 | 0,00% | Actions |
| US BANCORP \DE\ | $583 | 14 | 0,00% | Actions |
| Sunbelt Securities, Inc. | $344 | 11 | 0,00% | Actions |
| Allworth Financial LP | $292 | 7 | 0,00% | Actions |
| NATIONAL BANK OF CANADA /FI/ | $291 | 7 | 0,00% | Actions |
| Ameritas Advisory Services, LLC | $208 | 5 | 0,00% | Actions |
| Lindbrook Capital, LLC | $150 | 15 | 0,00% | Actions |
| IFP Advisors, Inc | $125 | 3 | 0,00% | Actions |
| Global Retirement Partners, LLC | $83 | 2 | 0,00% | Actions |
| KBC Group NV | $40 | 962 | 0,00% | Actions |
| ACADIAN ASSET MANAGEMENT LLC | $39 | 957 | 0,00% | Actions |
| Covestor Ltd | $1 | 17 | 0,00% | Actions |