CRNX Crinetics Pharmaceuticals, Inc. - Common Stock

NASDAQ · Pharmaceuticals · SEC EDGAR에서 보기 ↗
$84.77
가격 · 8월 19, 2026
기준 재무 정보 8월 3, 2026

Crinetics Pharmaceuticals, Inc. - Common Stock 정보 위키백과 회사 개요

Crinetics Pharmaceuticals is a global pharmaceutical company known for developing drugs for the treatment of endocrine-related diseases. It was founded by Scott Struthers, Frank Zhu, Ana Kusnetzow, and Stephen F. Betz in 2008 and is headquartered in San Diego, California. It went public on NASDAQ in 2018.

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Crinetics Pharmaceuticals is a global pharmaceutical company known for developing drugs for the treatment of endocrine-related diseases. It was founded by Scott Struthers, Frank Zhu, Ana Kusnetzow, and Stephen F. Betz in 2008 and is headquartered in San Diego, California. It went public on NASDAQ in 2018.

In July 2026, Vertex Pharmaceuticals agreed to acquire the company for $10 billion.

History

Struthers, Zhu, Kusnetzow, and Betz founded Crinetics in 2008 after previously working together on a small molecule drug for the treatment of endometriosis at Neurocrine Biosciences.

Crinetics expanded into a larger laboratory in 2010. After receiving NIH grant funding, Crinetics moved into its second laboratory.

In 2011, Crinetics Pharmaceuticals competed for the Michelson Prize, a competition sponsored by the Found Animals Foundation to develop a low-cost, non-surgical method for sterilizing dogs and cats, which would later lead to the licensing of a molecule for the treatment of acromegaly in large breed dogs.

Crinetics first synthesized its lead drug candidate to treat acromegaly. The drug was named paltusotine, in 2016. Crinetics Pharmaceuticals went public with an IPO in 2018. It conducted Phase II trials for paltusotine from 2019 to 2020. It conducted Phase III trials for paltusotine from 2021 to 2024. After the drug succeeded in a second Phase III study, the FDA accepted the company's new drug application for paltusotine and the company announced it was planning for a 2025 launch for the drug. The FDA set a Prescription Drug User Fee Act for the drug on September 25, 2025.

In 2021, Crinetics, together with 5AM Ventures and Frazier Healthcare Partners, formed an independently operated new company, Radionetics Oncology, aimed to develop a deep pipeline of novel, targeted, nonpeptide radiopharmaceuticals for the treatment of a broad range of oncology indications.

Crinetics partnered with the veterinary medicine company Loyal to develop a pill to extend the lifespans of large dogs in 2023.

In 2024, Scott Struthers received the Ernst & Young Entrepreneur of the Year Award for his work with Crinetics. In 2024, Crinetics was reported to have patent activity in rare diseases, health technology, and addiction therapies.

In 2024, Radionetics formed a strategic relationship with Eli Lilly and Company to take forward Radionetics’ proprietary GPCR targeting small molecule radiopharmaceuticals. Under the terms of the agreement, Radionetics received a $140 million upfront cash payment. As part of the strategic agreement, Lilly obtained the exclusive right to acquire Radionetics upon conclusion of an exercise period for $1 billion.

Crinetics also established its first office outside the United States in Zug, Switzerland in 2024.

In 2025, Crinetics Pharmaceuticals plans to file an Investigational New Drug for an oral thyroid stimulating hormone receptor antagonist and its nonpeptide drug conjugate (CRN09682). A total of four development candidates are currently in IND-enabling studies, including a PTH antagonist (Hyperparathyrodism), non-peptide drug conjugate (NETs and SST2-expressing solid tumors), TSH antagonist (Graves’ disease & TED) and SST3 agonist (ADPKD).

In July 2026, Vertex Pharmaceuticals agreed to acquire Crinetics for $10 billion.

Treatments

Crinetics’ pipeline focuses on synthesizing novel molecules for rare endocrine diseases. It is most known for developing paltusotine, a drug designed to treat the hormonal disorder acromegaly. Paltusotine works by helping moderate elevated IGF-1 levels, which is the main symptom of acromegaly. Paltusotine has also been tested as a treatment for carcinoid syndrome.

Crinetics has also developed oral treatments for neuroendocrine tumors, hyperinsulism, and Cushing's disease. The company's drug for treating Cushing's disease, Atumeltnant (also known as CRN049894), works by reducing levels of ACTH.

The company's pipeline also includes an oral parathyroid hormone inhibitor program for hyperparathyroidism and treatments for thyroid eye disease, Graves' disease, and obesity. Additionally, Crinetics nonpeptide drug conjugates (NDCs) include CRN09682, which is a somatostatin receptor 2 (SST2) targeted drug. NDCs are a new technology developed in-house by Crinetics.

== References ==

출처: 위키백과 (영어), CC BY-SA 4.0 · 위키백과에서 보기 ↗

Wikidata ↗

CRNX 주식 스냅샷 가격, 시가총액, P/E, EPS, ROE, 부채/자본, 52주 범위

가격
$84.77
시가총액
$8.10B
P/E (TTM)
-17.1
EPS (TTM)
$-4.95
매출 (TTM)
$8M
배당 수익률
ROE
-43.0%
부채/자본
52주 범위
$29 – $85

CRNX 주가 차트 기술 지표가 포함된 일일 OHLCV — 팬, 확대/축소 및 보기 사용자 정의

10년 성과 매출, 순이익, 마진 및 EPS 추세

매출 및 순이익 $8M
10-point trend, +1206.6%
2016-12-31 2025-12-31
EPS $-4.95
6-point trend, -104.5%
2020-12-31 2025-12-31
잉여현금흐름 $-384M
8-point trend, -1770.0%
2018-12-31 2025-12-31
마진 -6046.2%

가치 평가 P/E, P/S, P/B, EV/EBITDA 비율 — 주식이 비싼가요, 싼가요?

지표
5년 추세
CRNX
동종업계 중앙값
P/E (TTM)
5-point trend, +7.3%
-17.1
47.9
P/S (TTM)
5-point trend, -53.9%
1052.7
16.2
P/B
5-point trend, +10.1%
8.2
9.3
Price / FCF (주가 / FCF)
5-point trend, +23.7%
-21.1

수익성 총, 영업 및 순이익률; ROE, ROA, ROIC

지표
5년 추세
CRNX
동종업계 중앙값
Operating Margin (영업이익률)
5-point trend, +32.8%
-6714.8%
Net Profit Margin (순이익률)
5-point trend, +39.4%
-6046.2%
5.1%
ROA
5-point trend, +9.8%
-36.3%
0.81%
ROE
5-point trend, -5.0%
-43.0%
-15.3%
ROIC
5-point trend, -60.6%
-52.1%

재무 건전성 부채, 유동성, 지급능력 — 대차대조표 건전성

지표
5년 추세
CRNX
동종업계 중앙값
Current Ratio (유동비율)
5-point trend, -42.8%
12.3
2.7
Quick Ratio (당좌 비율)
5-point trend, -42.1%
12.1

성장 매출, EPS 및 순이익 성장률: YoY, 3년 CAGR, 5년 CAGR

지표
5년 추세
CRNX
동종업계 중앙값
Revenue YoY (매출 YoY)
5-point trend, +613.9%
640.7%
Revenue CAGR 3Y (매출 CAGR 3년)
5-point trend, +613.9%
17.6%
Revenue CAGR 5Y (매출 CAGR 5년)
5-point trend, +613.9%
155.3%

주당 지표 EPS, 주당 순자산, 주당 현금 흐름, 주당 배당금

지표
5년 추세
CRNX
동종업계 중앙값
EPS (Diluted) (EPS (희석))
5-point trend, -76.8%
$-4.95

자본 효율성 자산 회전율, 재고 회전율, 매출채권 회전율

지표
5년 추세
CRNX
동종업계 중앙값

CRNX 분석가 합의 강세 및 약세 애널리스트 의견, 12개월 목표 주가, 상승 여력

보유 21 명의 애널리스트
  • 적극 매수 3 14.3%
  • 매수 4 19.0%
  • 보유 14 66.7%
  • 매도 0 0.0%
  • 적극 매도 0 0.0%

12개월 목표 주가

10 명의 애널리스트 · 2026-08-13
중앙값 목표 $85.00 +0.3%
평균 목표 $85.50 +0.9%

실적 기록 EPS 실제 vs 예상, 서프라이즈 %, 달성률, 다음 실적 발표일

평균 서프라이즈
-0.01%
기간 EPS Actual EPS 예상 서프라이즈
2026년 6월 30일 $-1.14 $-1.23 0.09%
2026년 3월 31일 $-1.23 $-1.26 0.03%
2025년 12월 31일 $-1.29 $-1.39 0.10%
2025년 9월 30일 $-1.38 $-1.28 -0.10%
2025년 6월 30일 $-1.23 $-1.12 -0.11%
2025년 3월 31일 $-1.04 $-0.96 -0.08%

동종 기업 비교(GICS 하위 산업) 주요 지표 대 섹터 동종 기업

티커 시가총액 P/E 매출 YoY 순이익률 ROE 매출 총이익률
CRNX $4.45B -9.4 640.7% -6046.2% -43.0%
CORT $3.69B 42.4 12.8% 13.1% 15.5%
ELAN $11.25B -48.1 6.2% -4.9% -3.5% 55.0%
AXSM $9.29B -49.6 65.5% -28.7% -227.0%
LQDA $3.01B -43.1 1031.2% -43.5% -230.0%
BLTE
DFTX $1.32B -6.5 212.0% -71.0%
AMRX 57.3 8.1% 2.4% -80.0% 36.9%
LGND $3.74B 30.8 60.4% 46.4% 13.5%
LLY 46.8 44.7% 31.7% 101.2%

전체 기본 지표 연도별 모든 지표 — 손익계산서, 대차대조표, 현금흐름

손익계산서 17
CRNX의 연간 손익계산서 데이터
지표 추세 202520242023202220212020201920182017
Revenue 9-point trend, +276.3% $8M $1M $4M $5M $1M $71.0K $1M $2M $2M
Cost of Revenue 3-point trend, +1076000.00 $1M $0 $0 · · · · · ·
R&D Expense 9-point trend, +3496.4% $332M $240M $169M $130M $84M $57M $42M $24M $9M
SG&A Expense 9-point trend, +9767.5% $191M $100M $58M $42M $25M $18M $14M $7M $2M
Operating Expenses 9-point trend, +4594.5% $524M $340M $227M $173M $109M $75M $55M $31M $11M
Operating Income 9-point trend, -5562.0% $-517M $-339M $-223M $-168M $-108M $-75M $-54M $-29M $-9M
Interest Expense · · · · · · · · $8.0K
Interest Income 9-point trend, +199857.7% $52M $41M $13M $4M $157.0K $991.0K $3M $2M $26.0K
Other Non-op 9-point trend, -1090.0% $-357.0K $-519.0K $-159.0K $5M $61.0K $1M $3M $2M $-30.0K
Pretax Income 9-point trend, -4979.6% $-465M $-298M $-209M $-164M $-108M $-74M $-50M $-27M $-9M
Income Tax 9-point trend, +180000.00 $180.0K $0 $0 $0 $0 $0 $0 $0 $0
Net Income 9-point trend, -4981.5% $-465M $-298M $-215M $-164M $-108M $-74M $-50M $-27M $-9M
EPS (Basic) 6-point trend, -104.5% $-4.95 $-3.69 $-3.69 $-3.15 $-2.80 $-2.42 · · ·
EPS (Diluted) 6-point trend, -104.5% $-4.95 $-3.69 $-3.69 $-3.15 $-2.80 $-2.42 · · ·
Shares (Basic) 6-point trend, +208.9% 94,057,000 80,783,000 58,071,000 51,982,000 38,436,000 30,448,000 · · ·
Shares (Diluted) 6-point trend, +208.9% 94,057,000 80,783,000 58,071,000 51,982,000 38,436,000 30,448,000 · · ·
EBITDA 8-point trend, -1686.4% $-513M $-339M $-223M $-168M $-108M $-75M $-54M $-29M ·
대차대조표 24
CRNX의 연간 대차대조표 데이터
지표 추세 202520242023202220212020201920182017
Cash & Equivalents 9-point trend, +615.4% $102M $265M $55M $33M $201M $93M $40M $45M $14M
Short-term Investments 8-point trend, +679.1% $926M $1.09B $504M $302M $133M $78M $78M $119M ·
Receivables 2-point trend, +592000.00 $592.0K $0 · · · · · · ·
Inventory 2-point trend, +2022000.00 $2M $0 · · · · · · ·
Prepaid Expense 9-point trend, +1733.4% $18M $21M $16M $11M $11M $7M $5M $3M $973.0K
Other Current Assets 9-point trend, +1346.0% $3M $2M $448.0K $2M $912.0K $1M $668.0K $876.0K $239.0K
Current Assets 9-point trend, +6812.9% $1.05B $1.38B $574M $345M $345M $177M $123M $167M $15M
PP&E (Net) 9-point trend, +3474.0% $14M $12M $11M $4M $3M $3M $4M $4M $400.0K
PP&E (Gross) 9-point trend, +3060.2% $22M $20M $16M $8M $6M $6M $6M $5M $704.0K
Accum. Depreciation 9-point trend, +2515.8% $8M $8M $5M $4M $3M $3M $2M $741.0K $304.0K
Other Non-current Assets 7-point trend, +8472.7% · $3M $2M $37.0K $0 $40.0K $82.0K · $33.0K
Total Assets 9-point trend, +7120.5% $1.13B $1.43B $635M $352M $351M $183M $130M $171M $16M
Accounts Payable 9-point trend, +5510.7% $23M $6M $7M $7M $3M $6M $5M $5M $403.0K
Accrued Liabilities 2-point trend, +2240.8% · · · · · · · $4M $179.0K
Current Liabilities 9-point trend, +9384.1% $85M $60M $44M $28M $16M $10M $8M $8M $897.0K
Capital Leases 7-point trend, +767.2% $42M $45M $48M $2M $3M $4M $5M · ·
Other Non-current Liabilities 3-point trend, +3240000.00 $3M $829.0K $0 · · · · · ·
Total Liabilities 9-point trend, +14484.1% $134M $110M $96M $36M $19M $15M $13M $11M $920.0K
Common Stock 4-point trend, +25200.0% · · $253.0K $0 · · · $24.0K $1.0K
Retained Earnings 9-point trend, -8614.6% $-1.42B $-952M $-654M $-439M $-275M $-168M $-94M $-43M $-16M
AOCI 8-point trend, +2957.4% $2M $963.0K $977.0K $-4M $-382.0K $25.0K $148.0K $61.0K ·
Stockholders' Equity 9-point trend, +6704.2% $992M $1.32B $539M $316M $332M $169M $117M $160M $-15M
Liabilities + Equity 9-point trend, +7120.5% $1.13B $1.43B $635M $352M $351M $183M $130M $171M $16M
Shares Outstanding 9-point trend, +6067.8% 95,575,000 92,926,000 68,175,000 53,877,000 47,597,000 33,001,000 24,263,000 24,061 1,549,575
현금 흐름 13
CRNX의 연간 현금 흐름 데이터
지표 추세 202520242023202220212020201920182017
D&A 9-point trend, +2946.9% $4M $3M $1M $983.0K $922.0K $948.0K $887.0K $471.0K $128.0K
Stock-based Comp 9-point trend, +33488.2% $91M $69M $41M $28M $17M $10M $6M $2M $271.0K
Deferred Tax Flat — no change across 3 periods $0 $0 $0 · · · · · ·
Other Non-cash $-8M · · · · · · · ·
Operating Cash Flow 9-point trend, -3886.9% $-378M $-230M $-169M $-115M $-89M $-62M $-46M $-19M $-9M
CapEx 9-point trend, +1795.4% $6M $4M $5M $2M $436.0K $186.0K $492.0K $1M $304.0K
Investing Cash Flow 9-point trend, +57306.6% $174M $-575M $-200M $-174M $-56M $217.0K $42M $-119M $-304.0K
Stock Issued 7-point trend, -100.0% $0 $985M $370M $117M $250M $114M · $106M ·
Net Stock Activity 6-point trend, -100.0% $0 $970M $369M $117M $250M $114M · · ·
Financing Cash Flow 9-point trend, +243.5% $41M $1.01B $391M $122M $253M $115M $67.0K $170M $12M
Net Change in Cash 8-point trend, +10176.9% · $210M $22M $-167M $108M $53M $-5M $31M $2M
Taxes Paid 3-point trend, +89000.00 $89.0K $0 $0 · · · · · ·
Free Cash Flow 8-point trend, -1770.0% $-384M $-230M $-171M $-117M $-89M $-62M $-47M $-21M ·
수익성 7
CRNX의 연간 수익성 데이터
지표 추세 202520242023202220212020201920182017
Operating Margin 8-point trend, -467.9% -6714.8% -32613.5% -5547.2% -3544.1% -9990.9% -105567.6% -4512.3% -1182.5% ·
Net Margin 8-point trend, -441.4% -6046.2% -28720.7% -5345.9% -3460.4% -9985.2% -103960.6% -4226.5% -1116.8% ·
Pretax Margin 8-point trend, -441.2% -6043.9% -28720.7% -5345.9% -3460.4% -9985.2% -103960.6% -4226.5% -1116.8% ·
EBITDA Margin 8-point trend, -463.6% -6664.1% -32613.5% -5547.2% -3544.1% -9990.9% -105567.6% -4512.3% -1182.5% ·
ROA 8-point trend, -25.3% -36.3% -28.8% -43.5% -46.6% -40.3% -47.0% -33.4% -29.0% ·
ROE 8-point trend, -159.9% -43.0% -27.7% -39.5% -49.1% -41.0% -41.4% -40.9% -16.6% ·
ROIC 8-point trend, -190.8% -52.1% -25.6% -41.3% -53.1% -32.5% -44.4% -46.0% -17.9% ·
유동성 및 지급능력 2
CRNX의 연간 유동성 및 지급능력 데이터
지표 추세 202520242023202220212020201920182017
Current Ratio 8-point trend, -41.4% 12.3 23.0 13.1 12.5 21.6 16.9 14.8 21.0 ·
Quick Ratio 8-point trend, -41.5% 12.1 22.7 12.7 12.1 20.9 16.3 14.2 20.7 ·
효율성 3
CRNX의 연간 효율성 데이터
지표 추세 202520242023202220212020201920182017
Asset Turnover 8-point trend, -76.9% 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ·
Inventory Turnover 1.1 · · · · · · · ·
Receivables Turnover 26.0 · · · · · · · ·
주당 5
CRNX의 연간 주당 데이터
지표 추세 202520242023202220212020201920182017
Book Value / Share 8-point trend, +55.9% $10.38 $14.26 $7.91 $5.87 $6.97 $5.12 $4827.89 $6.66 ·
Revenue / Share 4-point trend, -10.2% $0.08 $0.01 $0.07 $0.09 · · · · ·
Cash Flow / Share 4-point trend, -81.3% $-4.02 $-2.80 $-2.86 $-2.22 · · · · ·
Cash / Share 8-point trend, -43.2% $1.06 $2.85 $0.81 $0.61 $4.22 $2.82 $1662.04 $1.87 ·
EPS (TTM) 6-point trend, -104.5% $-4.95 $-3.69 $-3.69 $-3.15 $-2.80 $-2.42 · · ·
성장률 3
CRNX의 연간 성장률 데이터
지표 추세 202520242023202220212020201920182017
Revenue YoY 5-point trend, -54.8% 640.7% -74.1% -15.3% 339.4% 1418.3% · · · ·
Revenue CAGR 3Y 3-point trend, -93.8% 17.6% -1.2% 283.8% · · · · · ·
Revenue CAGR 5Y 155.3% · · · · · · · ·
가치 평가 (TTM) 10
CRNX의 연간 가치 평가 (TTM) 데이터
지표 추세 202520242023202220212020201920182017
Revenue TTM 8-point trend, +217.0% $8M $1M $4M $5M $1M $71.0K $1M $2M ·
Net Income TTM 8-point trend, -1616.1% $-465M $-298M $-215M $-164M $-108M $-74M $-50M $-27M ·
Market Cap 8-point trend, +516.6% $4.45B $4.75B $2.43B $986M $1.35B $466M $608.8K $722M ·
P/E 6-point trend, -61.3% -9.4 -13.9 -9.6 -5.8 -10.1 -5.8 · · ·
P/S 8-point trend, +94.5% 578.1 4573.0 604.5 208.1 1254.4 6558.4 0.5 297.2 ·
P/B 8-point trend, -0.4% 4.5 3.6 4.5 3.1 4.1 2.8 0.0 4.5 ·
P / Tangible Book 6-point trend, +62.7% 4.5 3.6 4.5 3.1 4.1 2.8 · · ·
P / Cash Flow 8-point trend, +68.3% -11.8 -21.0 -14.6 -8.6 -15.3 -7.5 -0.0 -37.1 ·
P / FCF 8-point trend, +67.0% -11.6 -20.7 -14.2 -8.4 -15.2 -7.5 -0.0 -35.2 ·
Earnings Yield 6-point trend, +38.0% -10.6% -7.2% -10.4% -17.2% -9.9% -17.2% · · ·

재무제표 손익계산서, 대차대조표, 현금흐름 — 연간, 지난 5년

손익계산서
2025-12-312024-12-312023-12-312022-12-312021-12-31
매출 $8M$1M$4M$5M$1M
영업이익률 % -6714.8%-32613.5%-5547.2%-3544.1%-9990.9%
순이익 $-465M$-298M$-215M$-164M$-108M
희석 EPS $-4.95$-3.69$-3.69$-3.15$-2.80
대차대조표
2025-12-312024-12-312023-12-312022-12-312021-12-31
유동비율 12.323.013.112.521.6
당좌 비율 12.122.712.712.120.9
현금 흐름
2025-12-312024-12-312023-12-312022-12-312021-12-31
잉여현금흐름 $-384M$-230M$-171M$-117M$-89M

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기관 투자자 (13F) 287개의 제출자 · $3.2B 전체 · 기준일 2026년 6월 30일

분기별 SEC 양식 13F에서 이 주식을 보유하고 있다고 보고하는 기관. 롱 포지션만 해당하며, 단일 제출자는 별도의 옵션 레그에 대해 두 번 나타날 수 있습니다. 대규모 상쇄 풋/콜 포지션은 일반적으로 방향성에 대한 확신보다는 시장 조성 또는 헤지된 재고를 반영합니다.

기관 활동 — Q2 2026 대 이전 분기
신규 포지션 청산 포지션 증가함 감소 순주식 변동
63 (+17 이전 분기 대비) 30 (-14 이전 분기 대비) 95 (-17 이전 분기 대비) 63 (+3 이전 분기 대비) +21.6M

Q1 2026 대비 비교. SEC 양식 13F 제출은 분기 말로부터 45일 이내에 마감되며, 지연 제출자를 위한 짧은 유예 기간이 추가됩니다. 해당 기간 내에 있는 분기는 가장 최근에 완전히 보고된 쌍을 선호하여 건너뜁니다.

기관 가치 주식 % 추적된 13F 중 유형
FMR LLC $486,250,673 12,994,406 15.13% 주식
FARALLON CAPITAL MANAGEMENT, L.L.C. $336,372,047 8,989,098 10.46% 주식
Driehaus Capital Management LLC $241,866,078 6,463,551 7.52% 주식
WELLINGTON MANAGEMENT GROUP LLP $237,002,526 6,333,579 7.37% 주식
VANGUARD PORTFOLIO MANAGEMENT LLC $180,836,416 4,832,614 5.63% 주식
VANGUARD CAPITAL MANAGEMENT LLC $177,567,704 4,745,262 5.52% 주식
STATE STREET CORP $100,635,477 2,689,350 3.13% 주식
Bellevue Group AG $98,040,400 2,620,000 3.05% 주식
BAKER BROS. ADVISORS LP $87,991,820 2,351,465 2.74% 주식
GEODE CAPITAL MANAGEMENT, LLC $87,542,675 2,338,905 2.72% 주식
Polar Capital Holdings Plc $85,108,460 2,274,411 2.65% 주식
Pictet Asset Management Holding SA $77,572,984 2,075,375 2.41% 주식
Siren, L.L.C. $53,165,887 1,420,788 1.65% 주식
First Light Asset Management, LLC $50,923,606 1,360,866 1.58% 주식
NOVO HOLDINGS A/S $49,394,400 1,320,000 1.54% 주식
AMERICAN CENTURY COMPANIES INC $47,245,129 1,262,562 1.47% 주식
ADAR1 Capital Management, LLC $45,730,234 1,222,080 1.42% 주식
DIMENSIONAL FUND ADVISORS LP $44,555,208 1,190,679 1.39% 주식
MONTANOVA CAPITAL, LLC $44,390,560 1,186,279 1.38% 주식
ORBIMED ADVISORS LLC $37,382,580 999,000 1.16% 주식
Hood River Capital Management LLC $36,259,830 968,996 1.13% 주식
GOLDMAN SACHS GROUP INC $34,657,132 926,166 1.08% 주식
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $32,841,401 877,643 1.02% 주식
Aberdeen Group plc $30,699,181 820,395 0.95% 주식
Candriam S.C.A. $30,618,690 819,032 0.95% 주식
VANGUARD FIDUCIARY TRUST CO $28,230,995 754,436 0.88% 주식
Fisher Asset Management, LLC $27,748,912 741,553 0.86% 주식
SCHRODER INVESTMENT MANAGEMENT GROUP $17,709,036 479,400 0.55% 주식
AMERIPRISE FINANCIAL INC $17,451,149 466,356 0.54% 주식
Impax Asset Management Group plc $16,277,700 435,000 0.51% 주식
Prosight Management, LP $14,020,002 374,666 0.44% 주식
Universal- Beteiligungs- und Servicegesellschaft mbH $13,991,714 373,910 0.44% 주식
KENNEDY CAPITAL MANAGEMENT LLC $13,685,018 365,714 0.43% 주식
BRAUN STACEY ASSOCIATES INC $13,027,511 348,143 0.41% 주식
Fiera Capital Corp $12,395,263 331,247 0.39% 주식
BANK OF AMERICA CORP /DE/ $11,271,877 301,226 0.35% 주식
Defilade Capital Management, L.P. $8,959,845 239,440 0.28% 주식
SEB Asset Management AB $8,003,786 213,891 0.25% 주식
Foresite Capital Management VI LLC $7,933,414 212,010 0.25% 주식
RICE HALL JAMES & ASSOCIATES, LLC $7,346,220 196,318 0.23% 주식
TD Asset Management Inc $7,152,534 191,142 0.22% 주식
Swiss National Bank $6,877,796 183,800 0.21% 주식
SEGALL BRYANT & HAMILL, LLC $6,855,307 183,199 0.21% 주식
BlackRock, Inc. $6,781,290 181,221 0.21% 주식
JENNISON ASSOCIATES LLC $6,056,839 161,861 0.19% 주식
New Leaf Venture Partners, L.L.C. $5,872,650 141,000 0.18% 주식
SILVERCREST ASSET MANAGEMENT GROUP LLC $5,865,136 156,738 0.18% 주식
Foresite Capital Management IV, LLC $5,613,000 150,000 0.17% 주식
Bank of New York Mellon Corp $5,581,754 149,165 0.17% 주식
NEW YORK STATE COMMON RETIREMENT FUND $5,508,898 147,218 0.17% 주식
ENVESTNET ASSET MANAGEMENT INC $5,471,384 146,216 0.17% 주식
Moody Aldrich Partners LLC $5,466,201 146,077 0.17% 주식
Ishara Investments LP $5,369,770 143,500 0.17% 주식
CITADEL ADVISORS LLC $5,176,271 138,329 0.16% 주식
RHUMBLINE ADVISERS $4,861,141 129,908 0.15% 주식
ALLIANCEBERNSTEIN L.P. $4,782,618 131,680 0.15% 주식
GordonMD Global Investments LP $4,751,779 126,985 0.15% 주식
MANUFACTURERS LIFE INSURANCE COMPANY, THE $4,712,974 125,948 0.15% 주식
JANUS HENDERSON GROUP PLC $4,700,428 129,392 0.15% 주식
Cormorant Asset Management, LP $4,677,500 125,000 0.15% 주식
SECTOR GAMMA AS $4,289,380 114,628 0.13% 주식
XTX Topco Ltd $4,164,547 111,292 0.13% 주식
ALPS ADVISORS INC $3,981,825 106,409 0.12% 주식
FEDERATED HERMES, INC. $3,957,390 105,756 0.12% 주식
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $3,834,048 105,563 0.12% 주식
Nuveen Asset Management, LLC $3,760,151 73,541 0.12% 주식
Burkehill Global Management, LP $3,742,000 100,000 0.12% 주식
Nuveen, LLC $3,619,262 96,720 0.11% 주식
VICTORY CAPITAL MANAGEMENT INC $3,484,251 93,112 0.11% 주식
MORGAN STANLEY $3,320,829 88,744 0.10% 주식
TWO SIGMA INVESTMENTS, LP $3,266,729 87,299 0.10% 주식
VANGUARD ASSET MANAGEMENT, Ltd $3,254,754 86,979 0.10% 주식
AWM Investment Company, Inc. $3,180,700 85,000 0.10% 주식
Odyssean, LLC $3,160,344 84,456 0.10% 주식
Affinity Asset Advisors, LLC $2,806,500 75,000 0.09% 주식
ALGERT GLOBAL LLC $2,714,147 72,532 0.08% 주식
ExodusPoint Capital Management, LP $2,652,404 70,882 0.08% 주식
Ensign Peak Advisors, Inc $2,507,290 67,004 0.08% 주식
BARCLAYS PLC $2,466,127 65,904 0.08% 주식
FIRST TRUST ADVISORS LP $2,370,631 63,352 0.07% 주식
Man Group plc $2,284,229 61,043 0.07% 주식
MetLife Investment Management, LLC $2,258,709 60,361 0.07% 주식
CITIGROUP INC $2,255,229 60,268 0.07% 주식
Longaeva Partners L.P. $2,184,879 58,388 0.07% 주식
Swedbank AB $2,155,392 57,600 0.07% 주식
STATE OF WISCONSIN INVESTMENT BOARD $2,068,016 55,265 0.06% 주식
Jump Financial, LLC $1,923,388 51,400 0.06% 주식
Lighthouse Investment Partners, LLC $1,871,000 50,000 0.06% 주식
Vestmark Advisory Solutions, Inc. $1,823,252 48,724 0.06% 주식
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $1,787,254 47,762 0.06% 주식
VANGUARD GROUP INC $1,774,626 38,123 0.06% 주식
Point72 Asset Management, L.P. $1,735,577 46,381 0.05% 주식
BNP PARIBAS FINANCIAL MARKETS $1,696,398 45,334 0.05% 주식
RAYMOND JAMES FINANCIAL INC $1,606,254 42,925 0.05% 주식
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,549,188 41,400 0.05% 콜 옵션
Invesco Ltd. $1,545,446 41,300 0.05% 주식
Vanguard Global Advisers, LLC $1,485,986 39,711 0.05% 주식
HighMark Wealth Management LLC $1,444,224 38,595 0.04% 주식
OAK RIDGE INVESTMENTS LLC $1,405,046 37,548 0.04% 주식
Orion Porfolio Solutions, LLC $1,404,234 37,526 0.04% 주식

회사 내부자 20 명의 내부자 · 9 임원 · 10 이사

내부자 역할 마지막 활동 보유 주식 수 매수 12개월 매도 12개월 순매수/매도 12개월
Tobin Schilke Chief Financial Officer 2025년 3월 10일 A 52,000 0 0 $0
Marc Wilson CFO 2024년 9월 26일 M 111,092 0 0 $0
Jeff E. Knight Chief Operating Officer 2025년 3월 19일 S 87,491 0 0 $0
Stephen F. Betz Chief Scientific Officer 2025년 6월 12일 M 99,713 0 0 $0
Dana Pizzuti Chief Med and Dev Officer 2025년 3월 19일 S 72,233 0 0 $0
Isabel Kalofonos Chief Commercial Officer 2025년 1월 10일 A 0 0 $0
James Hassard Chief Commercial Officer 2024년 7월 5일 M 29,259 0 0 $0
Alan Seth Krasner Chief Medical Officer 2023년 10월 17일 M 43,210 0 0 $0
Ajay Madan Chief Development Officer 2022년 2월 28일 A 176,995 0 0 $0
Coelho Rogerio Vivaldi 이사 2026년 7월 2일 S 19,225 0 1 $-120,000
Caren Deardorf 이사 2026년 6월 18일 A 22,225 0 0 $0
Weston Nichols 이사 2026년 6월 18일 A 22,225 0 0 $0
Stephanie Okey 이사 2026년 6월 18일 A 12,325 0 2 $-246,143
Matthew K Fust 이사 2026년 6월 18일 A 28,761 0 0 $0
Camille L Bedrosian 이사 2026년 6월 18일 A 22,225 0 0 $0
Wendell Wierenga 이사 2026년 6월 18일 A 122,071 0 0 $0
Wendall Wierenga 이사 2025년 6월 11일 A 116,146 0 0 $0
Stephen W Kaldor 이사 2020년 6월 19일 A 0 0 $0
Jack Nielsen 이사 2019년 6월 21일 A 0 0 $0
Richard Scott Struthers 2026년 8월 7일 M 424,706 0 0 $0

SEC 양식 3/4/5 제출 서류 기준 내부자; 순매수/매도는 공개 시장 거래만 해당

행동주의자 및 5% 이상 소유자 1 보유

SEC 서류 13D를 제출한 투자자 — 발행인에 영향을 미치려는 의도로 5% 이상의 실질 소유권(행동주의 지분, 이사회 캠페인, M&A). 각 행은 해당 제출자의 포지션에 대한 가장 최근에 알려진 상태를 보여줍니다.

제출자 제출됨 지분 상태 목적 제출
Perceptive Advisors LLC, Joseph Edelman, Perceptive Life Sciences Master Fund, Ltd. ×6 제출 서류 2024년 3월 1일 최초 제출 SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF 보유 현황 55 ETF 보유

가중치는 직접적인 주식 보유(N-PORT)만 반영합니다. 레버리지 또는 파생 상품 기반 펀드는 표시되지 않은 추가 스왑 노출을 보유할 수 있습니다.

펀드 비중 단위 기준일 출처
SBIO · ALPS ETF Trust 2.37% 107,892 NS 2026년 5월 31일 N-PORT
IHE · iShares Trust 1.95% 376,636 SH 2026년 8월 8일 일간
FMED · Fidelity Covington Trust 1.65% 19,000 NS 2026년 5월 31일 N-PORT
PILL · Direxion Shares ETF Trust 1.40% 4,666 NS 2026년 4월 30일 N-PORT
BBP · ETFis Series Trust I 1.23% 18,743 NS 2026년 4월 30일 N-PORT
MMSC · First Trust Exchange-Traded Fund VI… 0.75% 11,043 NS 2026년 5월 31일 N-PORT
IBB · iShares Trust 0.63% 718,323 SH 2026년 8월 8일 일간
IBBQ · Invesco Exchange-Traded Fund Trust … 0.60% 5,737 SH 2026년 8월 8일 일간
IWO · iShares Trust 0.54% 940,202 SH 2026년 8월 8일 일간
NUSC · Nushares ETF Trust 0.28% 93,045 NS 2026년 4월 30일 N-PORT
ISCG · iShares Trust 0.27% 32,694 SH 2026년 8월 8일 일간
IWM · iShares Trust 0.27% 2,625,192 SH 2026년 8월 8일 일간
VTWG · VANGUARD SCOTTSDALE FUNDS 0.23% 110,770 SH 2026년 8월 8일 일간
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.20% 38,553 NS 2026년 4월 30일 N-PORT
BIB · ProShares Trust 0.19% 3,872 NS 2026년 5월 31일 N-PORT
ESML · iShares Trust 0.16% 55,438 SH 2026년 8월 8일 일간
BKSE · BNY Mellon ETF Trust 0.15% 3,142 NS 2026년 4월 30일 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.15% 51,135 SH 2026년 8월 8일 일간
FNY · First Trust Exchange-Traded AlphaDE… 0.14% 18,879 NS 2026년 4월 30일 N-PORT
ISCB · iShares Trust 0.13% 4,625 SH 2026년 8월 8일 일간
VTWO · VANGUARD SCOTTSDALE FUNDS 0.12% 596,648 SH 2026년 8월 8일 일간
RSSL · Global X Funds 0.12% 42,391 NS 2026년 4월 30일 N-PORT
VBK · VANGUARD INDEX FUNDS 0.11% 1,399,667 SH 2026년 8월 8일 일간
FFSM · FIDELITY COVINGTON TRUST 0.10% 31,759 NS 2026년 4월 30일 N-PORT
ITWO · ProShares Trust 0.09% 4,601 NS 2026년 5월 31일 N-PORT
OMFS · Invesco Exchange-Traded Self-Indexe… 0.09% 2,909 SH 2026년 8월 8일 일간
SCHA · SCHWAB STRATEGIC TRUST 0.08% 492,431 NS 2026년 5월 31일 N-PORT
FNX · First Trust Exchange-Traded AlphaDE… 0.07% 24,991 NS 2026년 4월 30일 N-PORT
WSML · iShares Trust 0.07% 5,742 SH 2026년 8월 8일 일간
FHLC · FIDELITY COVINGTON TRUST 0.06% 41,183 NS 2026년 4월 30일 N-PORT
DFAS · Dimensional ETF Trust 0.05% 196,549 NS 2026년 4월 30일 N-PORT
UWM · ProShares Trust 0.05% 3,599 NS 2026년 5월 31일 N-PORT
VB · VANGUARD INDEX FUNDS 0.05% 2,419,186 SH 2026년 8월 8일 일간
VHT · VANGUARD WORLD FUND 0.05% 275,155 SH 2026년 8월 8일 일간
FAD · First Trust Exchange-Traded AlphaDE… 0.04% 5,196 NS 2026년 4월 30일 N-PORT
VXF · VANGUARD INDEX FUNDS 0.04% 1,210,574 SH 2026년 8월 8일 일간
AVIE · AMERICAN CENTURY ETF TRUST 0.04% 112 NS 2026년 5월 31일 N-PORT
URTY · ProShares Trust 0.04% 3,643 NS 2026년 5월 31일 N-PORT
GSSC · Goldman Sachs ETF Trust 0.02% 5,689 NS 2026년 5월 31일 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.02% 3,773 NS 2026년 5월 31일 N-PORT
HDG · ProShares Trust 0.02% 91 NS 2026년 5월 31일 N-PORT
ITOT · iShares Trust 0.01% 146,419 SH 2026년 8월 8일 일간
IWV · iShares Trust 0.01% 27,043 SH 2026년 8월 8일 일간
DFAC · Dimensional ETF Trust 0.01% 125,853 NS 2026년 4월 30일 N-PORT
VTI · VANGUARD INDEX FUNDS 0.01% 3,342,704 SH 2026년 8월 8일 일간
VTHR · VANGUARD SCOTTSDALE FUNDS 0.01% 8,345 SH 2026년 8월 8일 일간
ESGV · VANGUARD WORLD FUND 0.01% 22,843 SH 2026년 8월 8일 일간
ONEQ · Fidelity Commonwealth Trust 0.01% 28,694 NS 2026년 5월 31일 N-PORT
DCOR · Dimensional ETF Trust 0.01% 5,863 NS 2026년 4월 30일 N-PORT
TILT · FlexShares Trust 0.01% 3,388 NS 2026년 4월 30일 N-PORT