| FMR LLC |
$241,280,071 |
9,506,701 |
15.37% |
주식
|
| SR One Capital Management, LP |
$127,860,735 |
5,037,854 |
8.15% |
주식
|
| NEA Management Company, LLC |
$102,109,298 |
4,023,219 |
6.50% |
주식
|
| ENAVATE SCIENCES GP, LLC |
$99,468,255 |
3,919,159 |
6.34% |
주식
|
| FEDERATED HERMES, INC. |
$79,104,511 |
3,116,805 |
5.04% |
주식
|
| BlackRock, Inc. |
$68,176,389 |
2,686,225 |
4.34% |
주식
|
| Capital International Investors |
$63,523,907 |
2,502,912 |
4.05% |
주식
|
| Polar Capital Holdings Plc |
$61,236,153 |
2,412,772 |
3.90% |
주식
|
| Royalty Pharma Sub-Manager, LLC |
$60,611,247 |
2,388,150 |
3.86% |
주식
|
| Fairmount Funds Management LLC |
$59,872,055 |
2,359,025 |
3.81% |
주식
|
| VANGUARD GROUP INC |
$52,760,791 |
1,453,065 |
3.36% |
주식
|
| STATE STREET CORP |
$52,158,438 |
2,055,100 |
3.32% |
주식
|
| NVP ASSOCIATES, LLC |
$46,660,673 |
1,838,482 |
2.97% |
주식
|
| WELLINGTON MANAGEMENT GROUP LLP |
$40,451,126 |
1,593,819 |
2.58% |
주식
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$34,386,448 |
1,354,864 |
2.19% |
주식
|
| BANK OF AMERICA CORP /DE/ |
$31,246,815 |
1,231,159 |
1.99% |
주식
|
| GEODE CAPITAL MANAGEMENT, LLC |
$22,406,450 |
882,654 |
1.43% |
주식
|
| ALLIANCEBERNSTEIN L.P. |
$21,571,235 |
1,103,388 |
1.37% |
주식
|
| TWO SIGMA INVESTMENTS, LP |
$20,688,507 |
815,150 |
1.32% |
주식
|
| EcoR1 Capital, LLC |
$20,037,510 |
789,500 |
1.28% |
주식
|
| MILLENNIUM MANAGEMENT LLC |
$16,762,729 |
660,470 |
1.07% |
주식
|
| Woodline Partners LP |
$14,987,880 |
590,539 |
0.95% |
주식
|
| Balyasny Asset Management L.P. |
$14,637,077 |
576,717 |
0.93% |
주식
|
| ArrowMark Colorado Holdings LLC |
$14,550,811 |
573,318 |
0.93% |
주식
|
| SILVERARC CAPITAL MANAGEMENT, LLC |
$12,938,445 |
509,789 |
0.82% |
주식
|
| Rock Springs Capital Management LP |
$12,742,714 |
502,077 |
0.81% |
주식
|
| Pivotal bioVenture Partners Investment Advisor LLC |
$12,455,641 |
490,766 |
0.79% |
주식
|
| NEXTBio Capital Management LP |
$10,830,560 |
426,736 |
0.69% |
주식
|
| Vestal Point Capital, LP |
$9,263,700 |
365,000 |
0.59% |
주식
|
| MARSHALL WACE, LLP |
$8,208,957 |
323,442 |
0.52% |
주식
|
| JENNISON ASSOCIATES LLC |
$7,970,564 |
314,049 |
0.51% |
주식
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$7,737,601 |
304,870 |
0.49% |
주식
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$7,666,917 |
302,085 |
0.49% |
주식
|
| NORTHERN TRUST CORP |
$7,135,334 |
281,140 |
0.45% |
주식
|
| GOLDMAN SACHS GROUP INC |
$6,882,117 |
271,163 |
0.44% |
주식
|
| VANGUARD FIDUCIARY TRUST CO |
$6,462,332 |
254,623 |
0.41% |
주식
|
| SPHERA FUNDS MANAGEMENT LTD. |
$5,858,567 |
230,834 |
0.37% |
주식
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$5,740,956 |
226,200 |
0.37% |
콜 옵션
|
| Walleye Capital LLC |
$5,305,689 |
209,050 |
0.34% |
주식
|
| Sio Capital Management, LLC |
$5,293,177 |
208,557 |
0.34% |
주식
|
| CITADEL ADVISORS LLC |
$4,968,897 |
195,780 |
0.32% |
주식
|
| UBS Group AG |
$4,519,899 |
178,089 |
0.29% |
주식
|
| Voleon Capital Management LP |
$4,242,140 |
167,145 |
0.27% |
주식
|
| BNP PARIBAS FINANCIAL MARKETS |
$3,834,563 |
151,086 |
0.24% |
주식
|
| MORGAN STANLEY |
$3,425,767 |
134,979 |
0.22% |
주식
|
| Squarepoint Ops LLC |
$3,177,195 |
125,185 |
0.20% |
주식
|
| BARCLAYS PLC |
$2,943,193 |
115,965 |
0.19% |
주식
|
| SEVEN GRAND MANAGERS, LLC |
$2,538,000 |
100,000 |
0.16% |
주식
|
| Birchview Capital, LP |
$2,375,593 |
93,601 |
0.15% |
주식
|
| Verition Fund Management LLC |
$1,852,435 |
72,988 |
0.12% |
주식
|
| Bank of New York Mellon Corp |
$1,788,706 |
70,477 |
0.11% |
주식
|
| J. Goldman & Co LP |
$1,731,728 |
68,232 |
0.11% |
주식
|
| Nuveen, LLC |
$1,691,273 |
66,638 |
0.11% |
주식
|
| ALPS ADVISORS INC |
$1,616,072 |
63,675 |
0.10% |
주식
|
| Swiss National Bank |
$1,350,216 |
53,200 |
0.09% |
주식
|
| Exome Asset Management LLC |
$1,331,003 |
52,443 |
0.08% |
주식
|
| Jump Financial, LLC |
$1,294,939 |
51,022 |
0.08% |
주식
|
| CITIGROUP INC |
$1,256,843 |
49,521 |
0.08% |
주식
|
| LOS ANGELES CAPITAL MANAGEMENT LLC |
$1,230,042 |
48,465 |
0.08% |
주식
|
| XTX Topco Ltd |
$1,016,063 |
40,034 |
0.06% |
주식
|
| Burkehill Global Management, LP |
$1,015,200 |
40,000 |
0.06% |
주식
|
| JANE STREET GROUP, LLC |
$989,820 |
39,000 |
0.06% |
콜 옵션
|
| Rafferty Asset Management, LLC |
$951,978 |
37,509 |
0.06% |
주식
|
| Atom Investors LP |
$942,842 |
37,149 |
0.06% |
주식
|
| RHUMBLINE ADVISERS |
$869,128 |
34,245 |
0.06% |
주식
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$844,646 |
33,280 |
0.05% |
주식
|
| AQR CAPITAL MANAGEMENT LLC |
$789,319 |
31,100 |
0.05% |
주식
|
| CITADEL ADVISORS LLC |
$784,242 |
30,900 |
0.05% |
콜 옵션
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$747,974 |
29,471 |
0.05% |
주식
|
| DEUTSCHE BANK AG\ |
$733,000 |
28,881 |
0.05% |
주식
|
| DCF Advisers, LLC |
$715,310 |
28,184 |
0.05% |
주식
|
| STATE OF WISCONSIN INVESTMENT BOARD |
$683,280 |
26,922 |
0.04% |
주식
|
| JPMORGAN CHASE & CO |
$660,518 |
24,445 |
0.04% |
주식
|
| WELLS FARGO & COMPANY/MN |
$659,753 |
25,995 |
0.04% |
주식
|
| VANGUARD ASSET MANAGEMENT, Ltd |
$523,412 |
20,623 |
0.03% |
주식
|
| Legal & General Group Plc |
$508,182 |
20,023 |
0.03% |
주식
|
| Invesco Ltd. |
$481,053 |
18,954 |
0.03% |
주식
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$479,682 |
18,900 |
0.03% |
풋 옵션
|
| China Universal Asset Management Co., Ltd. |
$478,362 |
18,848 |
0.03% |
주식
|
| PROFUND ADVISORS LLC |
$478,108 |
18,838 |
0.03% |
주식
|
| ALLSTATE CORP |
$462,957 |
18,241 |
0.03% |
주식
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$442,936 |
17,423 |
0.03% |
주식
|
| Y-Intercept (Hong Kong) Ltd |
$439,886 |
17,332 |
0.03% |
주식
|
| MetLife Investment Management, LLC |
$432,501 |
17,041 |
0.03% |
주식
|
| Virtus Investment Advisers, LLC |
$419,405 |
16,525 |
0.03% |
주식
|
| Point72 Asset Management, L.P. |
$409,532 |
16,136 |
0.03% |
주식
|
| Vanguard Global Advisers, LLC |
$389,126 |
15,332 |
0.02% |
주식
|
| NORDEA INVESTMENT MANAGEMENT AB |
$382,872 |
15,050 |
0.02% |
주식
|
| Brevan Howard Capital Management LP |
$372,426 |
14,674 |
0.02% |
주식
|
| Engineers Gate Manager LP |
$329,432 |
12,980 |
0.02% |
주식
|
| Russell Investments Group, Ltd. |
$323,341 |
12,740 |
0.02% |
주식
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$303,475 |
15,523 |
0.02% |
주식
|
| Creative Planning |
$297,530 |
11,723 |
0.02% |
주식
|
| VARCOV Co. |
$266,617 |
10,505 |
0.02% |
주식
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$261,414 |
10,300 |
0.02% |
주식
|
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ |
$229,765 |
9,053 |
0.01% |
주식
|
| Scientech Research LLC |
$229,131 |
9,028 |
0.01% |
주식
|
| DIMENSIONAL FUND ADVISORS LP |
$225,222 |
8,874 |
0.01% |
주식
|
| Quantinno Capital Management LP |
$217,786 |
8,581 |
0.01% |
주식
|
| State of New Jersey Common Pension Fund D |
$217,532 |
8,571 |
0.01% |
주식
|
| Police & Firemen's Retirement System of New Jersey |
$213,649 |
8,418 |
0.01% |
주식
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$203,852 |
8,032 |
0.01% |
주식
|
| Zurcher Kantonalbank (Zurich Cantonalbank) |
$191,949 |
7,563 |
0.01% |
주식
|
| KLP KAPITALFORVALTNING AS |
$154,818 |
6,100 |
0.01% |
주식
|
| PNC Financial Services Group, Inc. |
$120,277 |
4,739 |
0.01% |
주식
|
| Vanguard Investments Australia, Ltd. |
$106,571 |
4,199 |
0.01% |
주식
|
| Mirae Asset Global Investments Co., Ltd. |
$71,673 |
2,824 |
0.00% |
주식
|
| Ameritas Investment Partners, Inc. |
$65,633 |
2,586 |
0.00% |
주식
|
| TOUNJIAN ADVISORY PARTNERS, LLC |
$63,450 |
2,500 |
0.00% |
주식
|
| Quantbot Technologies LP |
$48,933 |
1,928 |
0.00% |
주식
|
| Tower Research Capital LLC (TRC) |
$32,639 |
1,286 |
0.00% |
주식
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$31,141 |
1,226,928 |
0.00% |
주식
|
| GF FUND MANAGEMENT CO. LTD. |
$28,882 |
1,138 |
0.00% |
주식
|
| SIGNATUREFD, LLC |
$28,781 |
1,134 |
0.00% |
주식
|
| CWM, LLC |
$28,778 |
1,472 |
0.00% |
주식
|
| ROYAL BANK OF CANADA |
$21,000 |
847 |
0.00% |
주식
|
| NISA INVESTMENT ADVISORS, LLC |
$16,522 |
651 |
0.00% |
주식
|
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. |
$13,680 |
539 |
0.00% |
주식
|
| Silver Grove Financial Group, Inc. |
$13,654 |
538 |
0.00% |
주식
|
| Larson Financial Group LLC |
$11,523 |
454 |
0.00% |
주식
|
| Global Retirement Partners, LLC |
$10,660 |
420 |
0.00% |
주식
|
| HARBOUR INVESTMENTS, INC. |
$9,391 |
370 |
0.00% |
주식
|
| GROUP ONE TRADING LLC |
$8,756 |
345 |
0.00% |
주식
|
| US BANCORP \DE\ |
$7,716 |
304 |
0.00% |
주식
|
| OSAIC HOLDINGS, INC. |
$7,487 |
295 |
0.00% |
주식
|
| J.Safra Asset Management Corp |
$5,685 |
224 |
0.00% |
주식
|
| iA Global Asset Management Inc. |
$5,460 |
215,130 |
0.00% |
주식
|
| GAMMA Investing LLC |
$4,949 |
195 |
0.00% |
주식
|
| EverSource Wealth Advisors, LLC |
$4,112 |
162 |
0.00% |
주식
|
| Arax Advisory Partners |
$2,640 |
104 |
0.00% |
주식
|
| Sterling Capital Management LLC |
$2,538 |
100 |
0.00% |
주식
|
| Bare Financial Services, Inc |
$2,412 |
95 |
0.00% |
주식
|
| Torren Management, LLC |
$1,857 |
95 |
0.00% |
주식
|
| CSM Advisors, LLC |
$1,716 |
67,622 |
0.00% |
주식
|
| Physician Wealth Advisors, Inc. |
$1,701 |
67 |
0.00% |
주식
|
| Ameritas Advisory Services, LLC |
$1,066 |
42 |
0.00% |
주식
|
| Fortitude Family Office, LLC |
$736 |
29 |
0.00% |
주식
|
| Cornerstone Financial Management LLC |
$660 |
26 |
0.00% |
주식
|
| ROTHSCHILD INVESTMENT LLC |
$508 |
20 |
0.00% |
주식
|
| CoreCap Advisors, LLC |
$305 |
12 |
0.00% |
주식
|
| HRT FINANCIAL LP |
$225 |
8,879 |
0.00% |
주식
|
| Sunbelt Securities, Inc. |
$215 |
11 |
0.00% |
주식
|
| SG Americas Securities, LLC |
$214 |
8,442 |
0.00% |
주식
|
| Caitong International Asset Management Co., Ltd |
$51 |
2 |
0.00% |
주식
|
| Essential Partners LLC |
$51 |
2 |
0.00% |
주식
|
| Allworth Financial LP |
$26 |
1 |
0.00% |
주식
|
| Hughes Financial Services, LLC |
$25 |
1 |
0.00% |
주식
|
| Freestone Grove Partners LP |
$25 |
1 |
0.00% |
주식
|
| Pacer Advisors, Inc. |
$16 |
626 |
0.00% |
주식
|
| Covestor Ltd |
$1 |
22 |
0.00% |
주식
|