| Nantahala Capital Management, LLC |
$13189017 |
12326184 |
14.15% |
股份
|
| Redmile Group, LLC |
$12333580 |
11526710 |
13.23% |
股份
|
| TCG Crossover Management, LLC |
$12187487 |
11390175 |
13.08% |
股份
|
| Prosight Management, LP |
$8372481 |
7824749 |
8.98% |
股份
|
| BlackRock, Inc. |
$7511500 |
7020093 |
8.06% |
股份
|
| VANGUARD GROUP INC |
$3987442 |
1129587 |
4.28% |
股份
|
| Point72 Asset Management, L.P. |
$3904584 |
3649144 |
4.19% |
股份
|
| MORGAN STANLEY |
$3264755 |
3051173 |
3.50% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$3102502 |
2899535 |
3.33% |
股份
|
| Vantage Consulting Group Inc |
$2410983 |
682998 |
2.59% |
股份
|
| CITADEL ADVISORS LLC |
$2197048 |
2053316 |
2.36% |
股份
|
| GOLDMAN SACHS GROUP INC |
$2048434 |
1914424 |
2.20% |
股份
|
| STATE STREET CORP |
$1803845 |
1685836 |
1.94% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$1546733 |
1445546 |
1.66% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$1378381 |
1288206 |
1.48% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$959888 |
897092 |
1.03% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$827553 |
773414 |
0.89% |
股份
|
| Blue Owl Capital Holdings LP |
$784918 |
733568 |
0.84% |
股份
|
| D. E. Shaw & Co., Inc. |
$769672 |
719320 |
0.83% |
股份
|
| Opaleye Management Inc. |
$749000 |
700000 |
0.80% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$704193 |
658125 |
0.76% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$698548 |
652849 |
0.75% |
股份
|
| NORTHERN TRUST CORP |
$635607 |
594025 |
0.68% |
股份
|
| PLATINUM INVESTMENT MANAGEMENT LTD |
$622322 |
581609 |
0.67% |
股份
|
| PANAGORA ASSET MANAGEMENT INC |
$612913 |
572816 |
0.66% |
股份
|
| UBS Group AG |
$556714 |
520293 |
0.60% |
股份
|
| SCHRODER INVESTMENT MANAGEMENT GROUP |
$431345 |
418782 |
0.46% |
股份
|
| TWO SIGMA ADVISERS, LP |
$425602 |
120567 |
0.46% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$406763 |
108470 |
0.44% |
股份
|
| WELLS FARGO & COMPANY/MN |
$328644 |
307144 |
0.35% |
股份
|
| Russell Investments Group, Ltd. |
$306664 |
286604 |
0.33% |
股份
|
| Bank of New York Mellon Corp |
$269260 |
251645 |
0.29% |
股份
|
| WELLINGTON MANAGEMENT GROUP LLP |
$250760 |
234355 |
0.27% |
股份
|
| Florida Trust Wealth Management Co |
$246565 |
230435 |
0.26% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$239742 |
224058 |
0.26% |
股份
|
| Nuveen, LLC |
$189061 |
176693 |
0.20% |
股份
|
| STATE OF WISCONSIN INVESTMENT BOARD |
$171414 |
160200 |
0.18% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$160500 |
150000 |
0.17% |
买入期权
|
| JPMORGAN CHASE & CO |
$157116 |
152540 |
0.17% |
股份
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$151238 |
141344 |
0.16% |
股份
|
| XTX Topco Ltd |
$150165 |
140341 |
0.16% |
股份
|
| FMR LLC |
$142069 |
132775 |
0.15% |
股份
|
| RHUMBLINE ADVISERS |
$125571 |
117364 |
0.13% |
股份
|
| Focus Partners Wealth |
$119627 |
111801 |
0.13% |
股份
|
| Quadrature Capital Ltd |
$113088 |
105690 |
0.12% |
股份
|
| Revolve Wealth Partners, LLC |
$107000 |
100000 |
0.11% |
股份
|
| Wilmington Savings Fund Society, FSB |
$107000 |
100000 |
0.11% |
股份
|
| DLK Investment Management, LLC |
$104770 |
33155 |
0.11% |
股份
|
| BARCLAYS PLC |
$100864 |
94264 |
0.11% |
股份
|
| DEUTSCHE BANK AG\ |
$89285 |
83444 |
0.10% |
股份
|
| DAFNA Capital Management LLC |
$82477 |
77081 |
0.09% |
股份
|
| JANE STREET GROUP, LLC |
$65556 |
61267 |
0.07% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$60458 |
56503 |
0.06% |
股份
|
| Invesco Ltd. |
$59665 |
55762 |
0.06% |
股份
|
| CITIGROUP INC |
$53149 |
49672 |
0.06% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$52719 |
49270 |
0.06% |
股份
|
| Verition Fund Management LLC |
$43153 |
40330 |
0.05% |
股份
|
| Magnetar Financial LLC |
$41828 |
39092 |
0.04% |
股份
|
| Brevan Howard Capital Management LP |
$39467 |
36885 |
0.04% |
股份
|
| CWM, LLC |
$38858 |
10362 |
0.04% |
股份
|
| SEI INVESTMENTS CO |
$35803 |
33461 |
0.04% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$34822 |
32544 |
0.04% |
股份
|
| Susquehanna Portfolio Strategies, LLC |
$30884 |
28864 |
0.03% |
股份
|
| INTECH INVESTMENT MANAGEMENT LLC |
$30252 |
28273 |
0.03% |
股份
|
| AXQ CAPITAL, LP |
$29325 |
27407 |
0.03% |
股份
|
| Cerity Partners LLC |
$29044 |
27144 |
0.03% |
股份
|
| Point72 Asset Management, L.P. |
$28248 |
26400 |
0.03% |
买入期权
|
| Creative Planning |
$25714 |
24032 |
0.03% |
股份
|
| Saxony Capital Management, LLC |
$25432 |
23768 |
0.03% |
股份
|
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
$24952 |
19343 |
0.03% |
股份
|
| NEUBERGER BERMAN GROUP LLC |
$22107 |
20661 |
0.02% |
股份
|
| Ground Swell Capital, LLC |
$21837 |
20408 |
0.02% |
股份
|
| Tower Research Capital LLC (TRC) |
$19646 |
18361 |
0.02% |
股份
|
| Centiva Capital, LP |
$18921 |
17683 |
0.02% |
股份
|
| Vanguard Personalized Indexing Management, LLC |
$18197 |
17007 |
0.02% |
股份
|
| COMMONWEALTH EQUITY SERVICES, LLC |
$16610 |
15519 |
0.02% |
股份
|
| PRUDENTIAL FINANCIAL INC |
$15296 |
14295 |
0.02% |
股份
|
| ProShare Advisors LLC |
$15026 |
14044 |
0.02% |
股份
|
| R Squared Ltd |
$14901 |
13926 |
0.02% |
股份
|
| Engineers Gate Manager LP |
$14438 |
13493 |
0.02% |
股份
|
| Pallas Capital Advisors LLC |
$13483 |
12601 |
0.01% |
股份
|
| Meridian Wealth Management, LLC |
$13457 |
12577 |
0.01% |
股份
|
| Perigon Wealth Management, LLC |
$11402 |
10656 |
0.01% |
股份
|
| AVISO WEALTH MANAGEMENT |
$11067 |
10343 |
0.01% |
股份
|
| LPL Financial LLC |
$10877 |
10165 |
0.01% |
股份
|
| Callan Family Office, LLC |
$10792 |
10086 |
0.01% |
股份
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$9737 |
9100 |
0.01% |
股份
|
| Legal & General Group Plc |
$9643 |
9012 |
0.01% |
股份
|
| SIMPLEX TRADING, LLC |
$8770 |
8197 |
0.01% |
股份
|
| Caitong International Asset Management Co., Ltd |
$7541 |
7048 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$7339 |
6859 |
0.01% |
股份
|
| State of Wyoming |
$6113 |
5713 |
0.01% |
股份
|
| ROYAL BANK OF CANADA |
$6000 |
5891 |
0.01% |
股份
|
| OSAIC HOLDINGS, INC. |
$4290 |
4009 |
0.00% |
股份
|
| JONES FINANCIAL COMPANIES LLLP |
$3060 |
3000 |
0.00% |
股份
|
| Optiver Holding B.V. |
$2895 |
2706 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$1928 |
1802 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$1531 |
1431 |
0.00% |
股份
|
| Arax Advisory Partners |
$1181 |
1104 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$691 |
646 |
0.00% |
股份
|
| Rockefeller Capital Management L.P. |
$462 |
431 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$396 |
370 |
0.00% |
股份
|
| ACADIAN ASSET MANAGEMENT LLC |
$380 |
360251 |
0.00% |
股份
|
| Essential Partners LLC |
$278 |
260 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$238 |
222 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$211 |
197 |
0.00% |
股份
|
| IFP Advisors, Inc |
$150 |
140 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$129 |
121 |
0.00% |
股份
|
| Allworth Financial LP |
$112 |
104 |
0.00% |
股份
|
| GROUP ONE TRADING LLC |
$107 |
100 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$81 |
74860 |
0.00% |
股份
|
| GSA CAPITAL PARTNERS LLP |
$59 |
54695 |
0.00% |
股份
|
| GAMMA Investing LLC |
$52 |
49 |
0.00% |
股份
|
| Clearstead Advisors, LLC |
$39 |
36 |
0.00% |
股份
|
| SJS Investment Consulting Inc. |
$35 |
32 |
0.00% |
股份
|
| State of Alaska, Department of Revenue |
$32 |
30000 |
0.00% |
股份
|
| Virtu Financial LLC |
$30 |
28174 |
0.00% |
股份
|
| HARBOUR INVESTMENTS, INC. |
$21 |
20 |
0.00% |
股份
|
| IFG Advisory, LLC |
$16 |
15 |
0.00% |
股份
|
| HUNTINGTON NATIONAL BANK |
$13 |
1 |
0.00% |
股份
|