| TCG Crossover Management, LLC |
$20100000 |
10000000 |
10.62% |
股份
|
| BlackRock, Inc. |
$15774236 |
7847879 |
8.33% |
股份
|
| VANGUARD GROUP INC |
$10776564 |
6908054 |
5.69% |
股份
|
| Nantahala Capital Management, LLC |
$8679399 |
4318109 |
4.58% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$8058773 |
4009340 |
4.26% |
股份
|
| Kynam Capital Management, LP |
$7655073 |
3808494 |
4.04% |
股份
|
| Merck & Co., Inc. |
$7126896 |
3545719 |
3.76% |
股份
|
| Balyasny Asset Management L.P. |
$6527326 |
3247426 |
3.45% |
股份
|
| 683 Capital Management, LLC |
$6432000 |
3200000 |
3.40% |
股份
|
| D. E. Shaw & Co., Inc. |
$5949566 |
2959983 |
3.14% |
股份
|
| ADAR1 Capital Management, LLC |
$5796002 |
2883583 |
3.06% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$5669191 |
2820493 |
2.99% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$4934077 |
2454271 |
2.61% |
股份
|
| Spruce Street Capital LP |
$4223147 |
2101068 |
2.23% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$3997558 |
1988835 |
2.11% |
股份
|
| Ikarian Capital, LLC |
$3985038 |
1982606 |
2.10% |
股份
|
| STATE STREET CORP |
$3778328 |
1879765 |
2.00% |
股份
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$3549517 |
1765929 |
1.87% |
股份
|
| MEDICI CAPITAL LLC |
$3321565 |
1652520 |
1.75% |
股份
|
| Affinity Asset Advisors, LLC |
$3035100 |
1510000 |
1.60% |
股份
|
| Eversept Partners, LP |
$2861985 |
1423873 |
1.51% |
股份
|
| FMR LLC |
$2806759 |
1396398 |
1.48% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$2632249 |
1309577 |
1.39% |
股份
|
| Euclidean Capital LLC |
$2628795 |
1307858 |
1.39% |
股份
|
| MACKENZIE FINANCIAL CORP |
$2230638 |
1109770 |
1.18% |
股份
|
| DEUTSCHE BANK AG\ |
$2207760 |
1098388 |
1.17% |
股份
|
| DEERFIELD MANAGEMENT COMPANY, L.P. |
$2120936 |
1055192 |
1.12% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$2101206 |
1045376 |
1.11% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$1879684 |
935166 |
0.99% |
股份
|
| DAFNA Capital Management LLC |
$1825786 |
908351 |
0.96% |
股份
|
| Elmind Capital, LP |
$1809000 |
900000 |
0.96% |
股份
|
| PANAGORA ASSET MANAGEMENT INC |
$1700458 |
845999 |
0.90% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$1645850 |
818831 |
0.87% |
股份
|
| NORTHERN TRUST CORP |
$1554659 |
773462 |
0.82% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$1333820 |
663592 |
0.70% |
股份
|
| MARSHALL WACE, LLP |
$1203105 |
598559 |
0.64% |
股份
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$1071029 |
532850 |
0.57% |
股份
|
| TWO SIGMA ADVISERS, LP |
$1016808 |
651800 |
0.54% |
股份
|
| Balyasny Asset Management L.P. |
$1012839 |
503900 |
0.53% |
买入期权
|
| New Leaf Venture Partners, L.L.C. |
$1005124 |
339569 |
0.53% |
股份
|
| GOLDMAN SACHS GROUP INC |
$872089 |
433875 |
0.46% |
股份
|
| XTX Topco Ltd |
$803359 |
399681 |
0.42% |
股份
|
| CITADEL ADVISORS LLC |
$786376 |
391232 |
0.42% |
股份
|
| CANTOR FITZGERALD, L. P. |
$593939 |
295492 |
0.31% |
股份
|
| UBS Group AG |
$550298 |
273780 |
0.29% |
股份
|
| Invesco Ltd. |
$516849 |
257139 |
0.27% |
股份
|
| Bank of New York Mellon Corp |
$502688 |
250093 |
0.27% |
股份
|
| AMERIPRISE FINANCIAL INC |
$451305 |
224530 |
0.24% |
股份
|
| NANO CAP NEW MILLENNIUM GROWTH FUND L P |
$402000 |
200000 |
0.21% |
股份
|
| LMR Partners LLP |
$402000 |
200000 |
0.21% |
股份
|
| Nuveen, LLC |
$354230 |
176234 |
0.19% |
股份
|
| Utah Retirement Systems |
$310123 |
154290 |
0.16% |
股份
|
| Cubist Systematic Strategies, LLC |
$296197 |
100067 |
0.16% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$286783 |
142678 |
0.15% |
股份
|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
$286425 |
142500 |
0.15% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$273159 |
135900 |
0.14% |
买入期权
|
| CANADA PENSION PLAN INVESTMENT BOARD |
$263913 |
131300 |
0.14% |
股份
|
| MORGAN STANLEY |
$242164 |
120480 |
0.13% |
股份
|
| JANE STREET GROUP, LLC |
$241401 |
120100 |
0.13% |
买入期权
|
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO |
$240736 |
119769 |
0.13% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$234221 |
108940 |
0.12% |
股份
|
| RHUMBLINE ADVISERS |
$220149 |
109532 |
0.12% |
股份
|
| CITADEL ADVISORS LLC |
$218889 |
108900 |
0.12% |
卖出期权
|
| STRS OHIO |
$204216 |
101600 |
0.11% |
股份
|
| Russell Investments Group, Ltd. |
$197973 |
98496 |
0.10% |
股份
|
| WELLS FARGO & COMPANY/MN |
$179236 |
89172 |
0.09% |
股份
|
| SIMPLEX TRADING, LLC |
$171830 |
85488 |
0.09% |
股份
|
| Blackstone Inc. |
$155061 |
77145 |
0.08% |
股份
|
| Jasper Ridge Partners, L.P. |
$147797 |
73531 |
0.08% |
股份
|
| SEI INVESTMENTS CO |
$143014 |
71151 |
0.08% |
股份
|
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main |
$140028 |
69666 |
0.07% |
股份
|
| IEQ CAPITAL, LLC |
$121746 |
60570 |
0.06% |
股份
|
| Verdad Advisers, LP |
$121623 |
60509 |
0.06% |
股份
|
| MetLife Investment Management, LLC |
$117979 |
58696 |
0.06% |
股份
|
| Mariner, LLC |
$105955 |
52709 |
0.06% |
股份
|
| Vanguard Personalized Indexing Management, LLC |
$99384 |
49445 |
0.05% |
股份
|
| HSBC HOLDINGS PLC |
$98016 |
48523 |
0.05% |
股份
|
| Graham Capital Management, L.P. |
$93457 |
46496 |
0.05% |
股份
|
| CITIGROUP INC |
$93012 |
46275 |
0.05% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$90832 |
45190 |
0.05% |
股份
|
| BARCLAYS PLC |
$90363 |
44957 |
0.05% |
股份
|
| JPMORGAN CHASE & CO |
$89435 |
42998 |
0.05% |
股份
|
| DIVERSIFIED TRUST CO |
$85125 |
42351 |
0.04% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$68037 |
33728 |
0.04% |
股份
|
| Cerity Partners LLC |
$65367 |
32521 |
0.03% |
股份
|
| Vanguard Global Advisers, LLC |
$62917 |
31302 |
0.03% |
股份
|
| CWM, LLC |
$62318 |
28985 |
0.03% |
股份
|
| Cannell & Spears LLC |
$60987 |
30342 |
0.03% |
股份
|
| Vontobel Holding Ltd. |
$60300 |
30000 |
0.03% |
股份
|
| Point72 Asset Management, L.P. |
$53665 |
26699 |
0.03% |
股份
|
| ROYAL BANK OF CANADA |
$53000 |
26122 |
0.03% |
股份
|
| MERCER GLOBAL ADVISORS INC /ADV |
$51263 |
25504 |
0.03% |
股份
|
| GROUP ONE TRADING LLC |
$50668 |
25208 |
0.03% |
股份
|
| INTECH INVESTMENT MANAGEMENT LLC |
$49305 |
24530 |
0.03% |
股份
|
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
$48704 |
30251 |
0.03% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$48487 |
24123 |
0.03% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$47086 |
23426 |
0.02% |
股份
|
| VOYA INVESTMENT MANAGEMENT LLC |
$44015 |
21898 |
0.02% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$42612 |
21200 |
0.02% |
股份
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$38988 |
19397 |
0.02% |
股份
|
| Qube Research & Technologies Ltd |
$33304 |
16569 |
0.02% |
股份
|
| CAPTRUST FINANCIAL ADVISORS |
$32234 |
16037 |
0.02% |
股份
|
| PRUDENTIAL FINANCIAL INC |
$32190 |
16015 |
0.02% |
股份
|
| Creative Planning |
$30180 |
15015 |
0.02% |
股份
|
| Tower Research Capital LLC (TRC) |
$29044 |
14450 |
0.02% |
股份
|
| Point72 (DIFC) Ltd |
$29030 |
9807 |
0.02% |
股份
|
| HAMILTON LANE ADVISORS LLC |
$28944 |
14400 |
0.02% |
股份
|
| Quadrature Capital Ltd |
$28480 |
14169 |
0.02% |
股份
|
| NEUBERGER BERMAN GROUP LLC |
$27177 |
13521 |
0.01% |
股份
|
| ProShare Advisors LLC |
$25824 |
12848 |
0.01% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$24924 |
12400 |
0.01% |
卖出期权
|
| Bronte Capital Management Pty Ltd. |
$23634 |
11758 |
0.01% |
股份
|
| Point72 Asia (Singapore) Pte. Ltd. |
$22602 |
7636 |
0.01% |
股份
|
| Merit Financial Group, LLC |
$22599 |
11243 |
0.01% |
股份
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$20723 |
10310 |
0.01% |
股份
|
| HighTower Advisors, LLC |
$20556 |
10227 |
0.01% |
股份
|
| Legal & General Group Plc |
$16775 |
8346 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$16432 |
8175 |
0.01% |
股份
|
| Arax Advisory Partners |
$10921 |
5433 |
0.01% |
股份
|
| ACADIAN ASSET MANAGEMENT LLC |
$8863 |
4414345 |
0.00% |
股份
|
| China Universal Asset Management Co., Ltd. |
$7236 |
3600 |
0.00% |
股份
|
| Allworth Financial LP |
$4983 |
2479 |
0.00% |
股份
|
| GAMMA Investing LLC |
$3061 |
1523 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$2846 |
1416 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$2631 |
1309 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$2561 |
1274 |
0.00% |
股份
|
| Essential Partners LLC |
$2486 |
1237 |
0.00% |
股份
|
| Optiver Holding B.V. |
$1859 |
925 |
0.00% |
股份
|
| CAROLINAS WEALTH CONSULTING LLC |
$1845 |
1500 |
0.00% |
股份
|
| True Wealth Design, LLC |
$1743 |
867 |
0.00% |
股份
|
| Physician Wealth Advisors, Inc. |
$1512 |
752 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$1367 |
680 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$1051 |
523 |
0.00% |
股份
|
| Federation des caisses Desjardins du Quebec |
$834 |
415 |
0.00% |
股份
|
| Wilmington Savings Fund Society, FSB |
$804 |
400 |
0.00% |
股份
|
| Hughes Financial Services, LLC |
$780 |
388 |
0.00% |
股份
|
| Rockefeller Capital Management L.P. |
$738 |
367 |
0.00% |
股份
|
| OSAIC HOLDINGS, INC. |
$603 |
300 |
0.00% |
股份
|
| MARK SHEPTOFF FINANCIAL PLANNING, LLC |
$603 |
300 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$509 |
253 |
0.00% |
股份
|
| NATIONAL BANK OF CANADA /FI/ |
$400 |
200 |
0.00% |
股份
|
| Fortitude Family Office, LLC |
$269 |
134 |
0.00% |
股份
|
| Clearstead Advisors, LLC |
$252 |
125 |
0.00% |
股份
|
| Wealth Enhancement Trust Services, Inc. |
$211 |
105 |
0.00% |
股份
|
| IFP Advisors, Inc |
$189 |
94 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$165 |
81655 |
0.00% |
股份
|
| Kingdom Financial Group LLC. |
$96 |
48 |
0.00% |
股份
|
| SJS Investment Consulting Inc. |
$87 |
43 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$84 |
42 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$40 |
20 |
0.00% |
股份
|
| JPL Wealth Management, LLC |
$37 |
18 |
0.00% |
股份
|
| Sunbelt Securities, Inc. |
$37 |
17 |
0.00% |
股份
|
| COMERICA BANK |
$14 |
9 |
0.00% |
股份
|
| FIFTH THIRD BANCORP |
$12 |
6 |
0.00% |
股份
|