| Alpha Wave Global, LP |
$97847707 |
3707757 |
12.28% |
股份
|
| Commodore Capital LP |
$71865142 |
2723196 |
9.02% |
股份
|
| BlackRock, Inc. |
$55973428 |
2121009 |
7.02% |
股份
|
| PERCEPTIVE ADVISORS LLC |
$42485076 |
1609893 |
5.33% |
股份
|
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
$42224000 |
1600000 |
5.30% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$36668298 |
1389477 |
4.60% |
股份
|
| Spruce Street Capital LP |
$35706910 |
1353047 |
4.48% |
股份
|
| Vivo Capital, LLC |
$31901763 |
1208858 |
4.00% |
股份
|
| FRANKLIN RESOURCES INC |
$26741172 |
1013307 |
3.36% |
股份
|
| VANGUARD GROUP INC |
$24312077 |
1365847 |
3.05% |
股份
|
| ARMISTICE CAPITAL, LLC |
$22800960 |
864000 |
2.86% |
股份
|
| Affinity Asset Advisors, LLC |
$22431500 |
850000 |
2.81% |
股份
|
| Vestal Point Capital, LP |
$20716150 |
785000 |
2.60% |
股份
|
| STATE STREET CORP |
$18102089 |
685945 |
2.27% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$17902152 |
678199 |
2.25% |
股份
|
| 72 Investment Holdings, LLC |
$17622661 |
667778 |
2.21% |
股份
|
| NORTHERN TRUST CORP |
$16696980 |
632701 |
2.10% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$14734065 |
558320 |
1.85% |
股份
|
| Point72 Asset Management, L.P. |
$13272851 |
502950 |
1.67% |
股份
|
| Integral Health Asset Management, LLC |
$13195000 |
500000 |
1.66% |
股份
|
| Venrock Adviser, LLC |
$13195000 |
500000 |
1.66% |
股份
|
| Driehaus Capital Management LLC |
$12867131 |
487576 |
1.61% |
股份
|
| Parkman Healthcare Partners LLC |
$11322234 |
429035 |
1.42% |
股份
|
| Ikarian Capital, LLC |
$10749651 |
407338 |
1.35% |
股份
|
| ORBIMED ADVISORS LLC |
$6804714 |
257852 |
0.85% |
股份
|
| Schonfeld Strategic Advisors LLC |
$6798881 |
257631 |
0.85% |
股份
|
| GOLDMAN SACHS GROUP INC |
$6249944 |
236830 |
0.78% |
股份
|
| MARSHALL WACE, LLP |
$5951025 |
225503 |
0.75% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$5575072 |
211257 |
0.70% |
股份
|
| AMERIPRISE FINANCIAL INC |
$5040385 |
190996 |
0.63% |
股份
|
| Saturn V Capital Management LP |
$4824857 |
182829 |
0.61% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$4779255 |
181101 |
0.60% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$3887221 |
147299 |
0.49% |
股份
|
| Eversept Partners, LP |
$3385468 |
128286 |
0.42% |
股份
|
| TWO SIGMA ADVISERS, LP |
$2849780 |
160100 |
0.36% |
股份
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$2803515 |
106234 |
0.35% |
股份
|
| ALKEON CAPITAL MANAGEMENT LLC |
$2694445 |
102101 |
0.34% |
股份
|
| STIFEL FINANCIAL CORP |
$2255827 |
85480 |
0.28% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$2126585 |
80583 |
0.27% |
股份
|
| AWM Investment Company, Inc. |
$2111200 |
80000 |
0.26% |
股份
|
| Bank of New York Mellon Corp |
$2014348 |
76330 |
0.25% |
股份
|
| MORGAN STANLEY |
$1977666 |
74940 |
0.25% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$1884220 |
71399 |
0.24% |
股份
|
| WELLINGTON MANAGEMENT GROUP LLP |
$1871393 |
70913 |
0.23% |
股份
|
| AdvisorShares Investments LLC |
$1867040 |
70748 |
0.23% |
股份
|
| Nuveen, LLC |
$1645205 |
62342 |
0.21% |
股份
|
| UBS Group AG |
$1549014 |
58697 |
0.19% |
股份
|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
$1336733 |
50653 |
0.17% |
股份
|
| XTX Topco Ltd |
$1229800 |
46601 |
0.15% |
股份
|
| TD Asset Management Inc |
$1155882 |
43800 |
0.15% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$1123185 |
42561 |
0.14% |
股份
|
| Quantinno Capital Management LP |
$1017493 |
38556 |
0.13% |
股份
|
| ALPS ADVISORS INC |
$939827 |
35613 |
0.12% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$881426 |
33400 |
0.11% |
买入期权
|
| RHUMBLINE ADVISERS |
$834866 |
31636 |
0.10% |
股份
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$797849 |
30233 |
0.10% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$736281 |
27900 |
0.09% |
卖出期权
|
| AMERICAN CENTURY COMPANIES INC |
$707780 |
26820 |
0.09% |
股份
|
| WELLS FARGO & COMPANY/MN |
$694136 |
26303 |
0.09% |
股份
|
| DEUTSCHE BANK AG\ |
$687486 |
26051 |
0.09% |
股份
|
| Allianz Asset Management GmbH |
$686140 |
26000 |
0.09% |
股份
|
| BROWN ADVISORY INC |
$659750 |
25000 |
0.08% |
股份
|
| JANE STREET GROUP, LLC |
$622804 |
23600 |
0.08% |
买入期权
|
| ALLIANCEBERNSTEIN L.P. |
$613704 |
27300 |
0.08% |
股份
|
| UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO |
$585198 |
22175 |
0.07% |
股份
|
| Squarepoint Ops LLC |
$561738 |
21286 |
0.07% |
股份
|
| CITIGROUP INC |
$547460 |
20745 |
0.07% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$504076 |
19101 |
0.06% |
股份
|
| Revisor Wealth Management LLC |
$452060 |
17130 |
0.06% |
股份
|
| SCS Capital Management LLC |
$444408 |
16840 |
0.06% |
股份
|
| MetLife Investment Management, LLC |
$412845 |
15644 |
0.05% |
股份
|
| Virtus Investment Advisers, LLC |
$402157 |
15239 |
0.05% |
股份
|
| CITADEL ADVISORS LLC |
$398489 |
15100 |
0.05% |
买入期权
|
| BANK OF NOVA SCOTIA |
$380016 |
14400 |
0.05% |
股份
|
| Invesco Ltd. |
$376190 |
14255 |
0.05% |
股份
|
| BARCLAYS PLC |
$351462 |
13318 |
0.04% |
股份
|
| Laird Norton Wetherby Wealth Management, LLC |
$338332 |
84162 |
0.04% |
股份
|
| Vanguard Personalized Indexing Management, LLC |
$334045 |
12658 |
0.04% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$316918 |
12009 |
0.04% |
股份
|
| JPMORGAN CHASE & CO |
$306075 |
10904 |
0.04% |
股份
|
| BANK OF MONTREAL /CAN/ |
$301242 |
11415 |
0.04% |
股份
|
| Vanguard Global Advisers, LLC |
$281027 |
10649 |
0.04% |
股份
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$242788 |
9200 |
0.03% |
股份
|
| GK Wealth Management LLC |
$226030 |
8565 |
0.03% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$211067 |
7998 |
0.03% |
股份
|
| IEQ CAPITAL, LLC |
$210803 |
7988 |
0.03% |
股份
|
| PROFUND ADVISORS LLC |
$208692 |
7908 |
0.03% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$203863 |
7725 |
0.03% |
股份
|
| Persistent Asset Partners Ltd |
$203150 |
7698 |
0.03% |
股份
|
| State of Wyoming |
$202781 |
7684 |
0.03% |
股份
|
| FMR LLC |
$166911 |
6325 |
0.02% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$102393 |
3880 |
0.01% |
股份
|
| ROYAL BANK OF CANADA |
$95000 |
3575 |
0.01% |
股份
|
| AlphaQuest LLC |
$68014 |
3821 |
0.01% |
股份
|
| Legal & General Group Plc |
$67110 |
2543 |
0.01% |
股份
|
| WHITTIER TRUST CO OF NEVADA INC |
$63787 |
2482 |
0.01% |
股份
|
| Russell Investments Group, Ltd. |
$63335 |
2400 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$62729 |
2377 |
0.01% |
股份
|
| Tower Research Capital LLC (TRC) |
$52675 |
1996 |
0.01% |
股份
|
| PNC Financial Services Group, Inc. |
$31668 |
1200 |
0.00% |
股份
|
| LOS ANGELES CAPITAL MANAGEMENT LLC |
$26548 |
1006 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$18077 |
685 |
0.00% |
股份
|
| STRS OHIO |
$15834 |
600 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$14778 |
560 |
0.00% |
股份
|
| JONES FINANCIAL COMPANIES LLLP |
$14412 |
533 |
0.00% |
股份
|
| Torren Management, LLC |
$12544 |
558 |
0.00% |
股份
|
| Accent Capital Management, LLC |
$9659 |
366 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$9527 |
361 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$9456 |
358279 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$8920 |
338 |
0.00% |
股份
|
| Aster Capital Management (DIFC) Ltd |
$3563 |
135 |
0.00% |
股份
|
| Optiver Holding B.V. |
$2956 |
112 |
0.00% |
股份
|
| FEDERATED HERMES, INC. |
$2903 |
110 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$2428 |
92 |
0.00% |
股份
|
| CWM, LLC |
$2293 |
102 |
0.00% |
股份
|
| Cornerstone Financial Management LLC |
$1821 |
69 |
0.00% |
股份
|
| ACADIAN ASSET MANAGEMENT LLC |
$1464 |
55509 |
0.00% |
股份
|
| US BANCORP \DE\ |
$1029 |
39 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$317 |
12 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$290 |
11 |
0.00% |
股份
|
| GAMMA Investing LLC |
$211 |
8 |
0.00% |
股份
|
| Arax Advisory Partners |
$132 |
5 |
0.00% |
股份
|
| OSAIC HOLDINGS, INC. |
$79 |
3 |
0.00% |
股份
|