| FMR LLC |
$55818898 |
12004064 |
19.54% |
股份
|
| BlackRock, Inc. |
$40548360 |
8720077 |
14.20% |
股份
|
| BML Capital Management, LLC |
$32328335 |
6952330 |
11.32% |
股份
|
| TANG CAPITAL MANAGEMENT LLC |
$22388355 |
4814700 |
7.84% |
股份
|
| VANGUARD GROUP INC |
$15090783 |
4227110 |
5.28% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$13786608 |
2964862 |
4.83% |
股份
|
| Bain Capital Life Sciences Investors, LLC |
$9651721 |
2075639 |
3.38% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$9108898 |
1958435 |
3.19% |
股份
|
| STATE STREET CORP |
$7683655 |
1652399 |
2.69% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$7006141 |
1506697 |
2.45% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$6042497 |
1299515 |
2.12% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$5260080 |
1131200 |
1.84% |
股份
|
| Rosalind Advisors, Inc. |
$4978058 |
1070550 |
1.74% |
股份
|
| JPMORGAN CHASE & CO |
$4360682 |
945918 |
1.53% |
股份
|
| TWO SIGMA ADVISERS, LP |
$3783129 |
1059700 |
1.32% |
股份
|
| NORTHERN TRUST CORP |
$3511862 |
755239 |
1.23% |
股份
|
| MORGAN STANLEY |
$3345743 |
719514 |
1.17% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$2930360 |
630185 |
1.03% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$2839323 |
610607 |
0.99% |
股份
|
| GOLDMAN SACHS GROUP INC |
$2468480 |
530856 |
0.86% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$2184575 |
469801 |
0.76% |
股份
|
| CM Management, LLC |
$1650750 |
355000 |
0.58% |
股份
|
| BARCLAYS PLC |
$1621239 |
348653 |
0.57% |
股份
|
| D. E. Shaw & Co., Inc. |
$1605115 |
345186 |
0.56% |
股份
|
| BANQUE PICTET & CIE SA |
$1604608 |
345077 |
0.56% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$1416441 |
304611 |
0.50% |
股份
|
| Nuveen, LLC |
$1321916 |
284283 |
0.46% |
股份
|
| Invesco Ltd. |
$1242132 |
267125 |
0.43% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$1151852 |
247710 |
0.40% |
股份
|
| Quantinno Capital Management LP |
$1126704 |
242302 |
0.39% |
股份
|
| Opaleye Management Inc. |
$1092750 |
235000 |
0.38% |
股份
|
| HSBC HOLDINGS PLC |
$1023272 |
221009 |
0.36% |
股份
|
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
$979020 |
210542 |
0.34% |
股份
|
| WELLINGTON MANAGEMENT GROUP LLP |
$961551 |
206785 |
0.34% |
股份
|
| Bank of New York Mellon Corp |
$880952 |
189452 |
0.31% |
股份
|
| Auour Investments LLC |
$823050 |
177000 |
0.29% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$793555 |
170657 |
0.28% |
股份
|
| CITADEL ADVISORS LLC |
$731092 |
157224 |
0.26% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$668304 |
124220 |
0.23% |
股份
|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
$608685 |
130900 |
0.21% |
股份
|
| STATE OF WISCONSIN INVESTMENT BOARD |
$552220 |
118757 |
0.19% |
股份
|
| STRS OHIO |
$547305 |
117700 |
0.19% |
股份
|
| Jump Financial, LLC |
$476258 |
102421 |
0.17% |
股份
|
| UBS Group AG |
$439457 |
94507 |
0.15% |
股份
|
| RHUMBLINE ADVISERS |
$423720 |
91124 |
0.15% |
股份
|
| Aldebaran Capital, LLC |
$410037 |
88180 |
0.14% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$380044 |
81730 |
0.13% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$366053 |
78721 |
0.13% |
股份
|
| DEUTSCHE BANK AG\ |
$327360 |
70400 |
0.11% |
股份
|
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. |
$326000 |
70000 |
0.11% |
股份
|
| Susquehanna Portfolio Strategies, LLC |
$288639 |
62073 |
0.10% |
股份
|
| WELLS FARGO & COMPANY/MN |
$277680 |
59716 |
0.10% |
股份
|
| Russell Investments Group, Ltd. |
$254874 |
54892 |
0.09% |
股份
|
| Cubist Systematic Strategies, LLC |
$254545 |
87774 |
0.09% |
股份
|
| Rangeley Capital, LLC |
$202275 |
43500 |
0.07% |
股份
|
| MetLife Investment Management, LLC |
$183517 |
39466 |
0.06% |
股份
|
| ALGERT GLOBAL LLC |
$179118 |
38520 |
0.06% |
股份
|
| NANO CAP NEW MILLENNIUM GROWTH FUND L P |
$162750 |
35000 |
0.06% |
股份
|
| CITIGROUP INC |
$160955 |
34614 |
0.06% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$151860 |
32658 |
0.05% |
股份
|
| RBF Capital, LLC |
$139500 |
30000 |
0.05% |
股份
|
| Squarepoint Ops LLC |
$136319 |
29316 |
0.05% |
股份
|
| MERCER GLOBAL ADVISORS INC /ADV |
$129549 |
27860 |
0.05% |
股份
|
| Vanguard Global Advisers, LLC |
$119417 |
25681 |
0.04% |
股份
|
| JOHNSON INVESTMENT COUNSEL INC |
$118993 |
25590 |
0.04% |
股份
|
| Certified Advisory Corp |
$113925 |
24500 |
0.04% |
股份
|
| Creative Planning |
$107429 |
23103 |
0.04% |
股份
|
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM |
$102347 |
22010 |
0.04% |
股份
|
| SEI INVESTMENTS CO |
$88527 |
19038 |
0.03% |
股份
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$82296 |
17698 |
0.03% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$78762 |
16938 |
0.03% |
股份
|
| Engineers Gate Manager LP |
$78148 |
16806 |
0.03% |
股份
|
| INTECH INVESTMENT MANAGEMENT LLC |
$77446 |
16655 |
0.03% |
股份
|
| Headlands Technologies LLC |
$77278 |
16619 |
0.03% |
股份
|
| Cerity Partners LLC |
$76590 |
16471 |
0.03% |
股份
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$76009 |
16346 |
0.03% |
股份
|
| VOYA INVESTMENT MANAGEMENT LLC |
$75525 |
16242 |
0.03% |
股份
|
| Spark Investment Management LLC |
$75330 |
16200 |
0.03% |
股份
|
| Graham Capital Management, L.P. |
$75074 |
16145 |
0.03% |
股份
|
| BAILARD, INC. |
$74865 |
16100 |
0.03% |
股份
|
| RFG Advisory, LLC |
$69169 |
14875 |
0.02% |
股份
|
| Trexquant Investment LP |
$68592 |
14751 |
0.02% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$63752 |
13710 |
0.02% |
股份
|
| China Universal Asset Management Co., Ltd. |
$59222 |
12736 |
0.02% |
股份
|
| PRUDENTIAL FINANCIAL INC |
$56637 |
12180 |
0.02% |
股份
|
| NEUBERGER BERMAN GROUP LLC |
$56158 |
12077 |
0.02% |
股份
|
| Sunpointe, LLC |
$55535 |
11943 |
0.02% |
股份
|
| ProShare Advisors LLC |
$55367 |
11907 |
0.02% |
股份
|
| BLAIR WILLIAM & CO/IL |
$52661 |
11325 |
0.02% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$52080 |
11200 |
0.02% |
买入期权
|
| WOLVERINE TRADING, LLC |
$43747 |
14982 |
0.02% |
股份
|
| Blue Trust, Inc. |
$40455 |
8700 |
0.01% |
股份
|
| Legal & General Group Plc |
$32931 |
7082 |
0.01% |
股份
|
| Tower Research Capital LLC (TRC) |
$28844 |
6203 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$27500 |
5914 |
0.01% |
股份
|
| Versant Capital Management, Inc |
$22908 |
4397 |
0.01% |
股份
|
| Arax Advisory Partners |
$19642 |
4224 |
0.01% |
股份
|
| Mirae Asset Global Investments Co., Ltd. |
$16642 |
3579 |
0.01% |
股份
|
| Smartleaf Asset Management LLC |
$15332 |
3325 |
0.01% |
股份
|
| ROYAL BANK OF CANADA |
$15000 |
3218 |
0.01% |
股份
|
| SIMPLEX TRADING, LLC |
$13638 |
2933 |
0.00% |
股份
|
| PNC Financial Services Group, Inc. |
$12950 |
2785 |
0.00% |
股份
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$12476 |
2319 |
0.00% |
股份
|
| Point72 Asia (Singapore) Pte. Ltd. |
$10443 |
3601 |
0.00% |
股份
|
| Rockefeller Capital Management L.P. |
$10295 |
2214 |
0.00% |
股份
|
| ACADIAN ASSET MANAGEMENT LLC |
$9455 |
2035192 |
0.00% |
股份
|
| GF FUND MANAGEMENT CO. LTD. |
$7700 |
1656 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$6645 |
1429 |
0.00% |
股份
|
| CWM, LLC |
$5525 |
1027 |
0.00% |
股份
|
| OSAIC HOLDINGS, INC. |
$4770 |
1026 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$4543 |
977 |
0.00% |
股份
|
| Allworth Financial LP |
$2037 |
438 |
0.00% |
股份
|
| Essential Partners LLC |
$1367 |
294 |
0.00% |
股份
|
| SJS Investment Consulting Inc. |
$1191 |
256 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$1132 |
245 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$972 |
209 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$660 |
142 |
0.00% |
股份
|
| GROUP ONE TRADING LLC |
$651 |
140 |
0.00% |
股份
|
| ZIONS BANCORPORATION, NATIONAL ASSOCIATION /UT/ |
$595 |
128 |
0.00% |
股份
|
| Global Retirement Partners, LLC |
$572 |
123 |
0.00% |
股份
|
| True Wealth Design, LLC |
$568 |
122 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$539 |
115808 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$493 |
106 |
0.00% |
股份
|
| REAP Financial Group, LLC |
$465 |
100 |
0.00% |
股份
|
| GAMMA Investing LLC |
$423 |
91 |
0.00% |
股份
|
| IFP Advisors, Inc |
$339 |
73 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$112 |
24 |
0.00% |
股份
|
| Clearstead Advisors, LLC |
$103 |
22 |
0.00% |
股份
|
| FNY Investment Advisers, LLC |
$23 |
5000 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$9 |
2 |
0.00% |
股份
|
| Covestor Ltd |
$0 |
36 |
0.00% |
股份
|