| L1 Capital Pty Ltd |
$76721650 |
7789000 |
11.88% |
股份
|
| FMR LLC |
$67650648 |
6868086 |
10.48% |
股份
|
| BlackRock, Inc. |
$56846447 |
5771213 |
8.80% |
股份
|
| Sio Capital Management, LLC |
$54627942 |
5545984 |
8.46% |
股份
|
| PERCEPTIVE ADVISORS LLC |
$33740939 |
3425476 |
5.23% |
股份
|
| Nantahala Capital Management, LLC |
$33325850 |
3383335 |
5.16% |
股份
|
| ADAR1 Capital Management, LLC |
$30979196 |
3145096 |
4.80% |
股份
|
| RA CAPITAL MANAGEMENT, L.P. |
$29550000 |
3000000 |
4.58% |
股份
|
| BVF INC/IL |
$29550000 |
3000000 |
4.58% |
股份
|
| Ensign Peak Advisors, Inc |
$23543470 |
2390200 |
3.65% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$20712784 |
2102303 |
3.21% |
股份
|
| STATE STREET CORP |
$16835600 |
1709198 |
2.61% |
股份
|
| Rhenman & Partners Asset Management AB |
$15155456 |
1538625 |
2.35% |
股份
|
| Vestal Point Capital, LP |
$9948500 |
1010000 |
1.54% |
股份
|
| Affinity Asset Advisors, LLC |
$8987110 |
912397 |
1.39% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$8665833 |
879780 |
1.34% |
股份
|
| MONTANOVA CAPITAL, LLC |
$8372500 |
850000 |
1.30% |
股份
|
| UBS Group AG |
$7408855 |
752168 |
1.15% |
股份
|
| Velan Capital Investment Management LP |
$6895000 |
700000 |
1.07% |
股份
|
| Militia Capital Management LLC |
$6599500 |
670000 |
1.02% |
股份
|
| Assenagon Asset Management S.A. |
$6349980 |
644668 |
0.98% |
股份
|
| NORTHERN TRUST CORP |
$6265467 |
636088 |
0.97% |
股份
|
| CITADEL ADVISORS LLC |
$6008933 |
610044 |
0.93% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$5401110 |
548336 |
0.84% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$4442852 |
451051 |
0.69% |
股份
|
| VANGUARD GROUP INC |
$4198282 |
841339 |
0.65% |
股份
|
| GOLDMAN SACHS GROUP INC |
$3743295 |
380030 |
0.58% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$3472125 |
352500 |
0.54% |
股份
|
| FEDERATED HERMES, INC. |
$3364179 |
341541 |
0.52% |
股份
|
| Balyasny Asset Management L.P. |
$3177945 |
322634 |
0.49% |
股份
|
| JPMORGAN CHASE & CO |
$3169053 |
324034 |
0.49% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$2483717 |
252154 |
0.38% |
股份
|
| PRUDENTIAL FINANCIAL INC |
$2410443 |
244715 |
0.37% |
股份
|
| Bank of New York Mellon Corp |
$2291760 |
232666 |
0.35% |
股份
|
| Invesco Ltd. |
$2067437 |
209892 |
0.32% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$1907167 |
193621 |
0.30% |
股份
|
| Holocene Advisors, LP |
$1762007 |
178884 |
0.27% |
股份
|
| Nuveen, LLC |
$1705606 |
173158 |
0.26% |
股份
|
| Ikarian Capital, LLC |
$1640724 |
166571 |
0.25% |
股份
|
| Eversept Partners, LP |
$1637356 |
166229 |
0.25% |
股份
|
| FRED ALGER MANAGEMENT, LLC |
$1263331 |
128257 |
0.20% |
股份
|
| MORGAN STANLEY |
$1224926 |
124358 |
0.19% |
股份
|
| Symmetry Investments LP |
$1178060 |
119600 |
0.18% |
股份
|
| Susquehanna Portfolio Strategies, LLC |
$1156843 |
117446 |
0.18% |
股份
|
| AWM Investment Company, Inc. |
$1132750 |
115000 |
0.18% |
股份
|
| BARCLAYS PLC |
$1066647 |
108289 |
0.17% |
股份
|
| BEARING POINT CAPITAL, LLC |
$1005291 |
102060 |
0.16% |
股份
|
| Empower Advisory Group, LLC |
$995658 |
101082 |
0.15% |
股份
|
| RHUMBLINE ADVISERS |
$963873 |
97856 |
0.15% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$955766 |
97032 |
0.15% |
股份
|
| Marex Group Ltd |
$935100 |
94934 |
0.14% |
股份
|
| DEUTSCHE BANK AG\ |
$889543 |
90309 |
0.14% |
股份
|
| WELLS FARGO & COMPANY/MN |
$870916 |
88418 |
0.13% |
股份
|
| Quinn Opportunity Partners LLC |
$738750 |
75000 |
0.11% |
股份
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$713376 |
72424 |
0.11% |
股份
|
| MACQUARIE GROUP LTD |
$698316 |
70895 |
0.11% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$618767 |
62819 |
0.10% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$598880 |
60800 |
0.09% |
买入期权
|
| SummitTX Capital, L.P. |
$575073 |
58383 |
0.09% |
股份
|
| Alyeska Investment Group, L.P. |
$570532 |
57922 |
0.09% |
股份
|
| Numerai GP LLC |
$535810 |
54397 |
0.08% |
股份
|
| Walleye Capital LLC |
$535771 |
54393 |
0.08% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$534757 |
54290 |
0.08% |
股份
|
| Caption Management, LLC |
$492500 |
50000 |
0.08% |
买入期权
|
| MetLife Investment Management, LLC |
$477784 |
48506 |
0.07% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$447885 |
80700 |
0.07% |
股份
|
| Vanguard Global Advisers, LLC |
$415739 |
42207 |
0.06% |
股份
|
| JANE STREET GROUP, LLC |
$415670 |
42200 |
0.06% |
卖出期权
|
| Persistent Asset Partners Ltd |
$413109 |
41940 |
0.06% |
股份
|
| Wellington Shields & Co., LLC |
$389410 |
39534 |
0.06% |
股份
|
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. |
$386445 |
39233 |
0.06% |
股份
|
| CITIGROUP INC |
$371848 |
37751 |
0.06% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$370685 |
37633 |
0.06% |
股份
|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
$344750 |
35000 |
0.05% |
股份
|
| Y-Intercept (Hong Kong) Ltd |
$339549 |
34472 |
0.05% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$330842 |
33588 |
0.05% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$319140 |
32400 |
0.05% |
卖出期权
|
| PRINCIPAL FINANCIAL GROUP INC |
$287099 |
29147 |
0.04% |
股份
|
| LPL Financial LLC |
$282764 |
28707 |
0.04% |
股份
|
| FOX RUN MANAGEMENT, L.L.C. |
$280833 |
28511 |
0.04% |
股份
|
| Cetera Investment Advisers |
$267979 |
27206 |
0.04% |
股份
|
| XTX Topco Ltd |
$264916 |
26895 |
0.04% |
股份
|
| GDS Wealth Management |
$257085 |
26100 |
0.04% |
股份
|
| Russell Investments Group, Ltd. |
$253499 |
25736 |
0.04% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$251874 |
25571 |
0.04% |
股份
|
| SEVEN GRAND MANAGERS, LLC |
$246250 |
25000 |
0.04% |
股份
|
| Brevan Howard Capital Management LP |
$232667 |
23621 |
0.04% |
股份
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$231475 |
23500 |
0.04% |
股份
|
| JANE STREET GROUP, LLC |
$218670 |
22200 |
0.03% |
买入期权
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$214700 |
21797 |
0.03% |
股份
|
| SIMPLEX TRADING, LLC |
$199649 |
20269 |
0.03% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$193602 |
19655 |
0.03% |
股份
|
| EWA, LLC |
$190105 |
19300 |
0.03% |
股份
|
| Oasis Management Co Ltd. |
$180285 |
18303 |
0.03% |
股份
|
| Dynamic Technology Lab Private Ltd |
$173000 |
17600 |
0.03% |
股份
|
| INTECH INVESTMENT MANAGEMENT LLC |
$171232 |
17384 |
0.03% |
股份
|
| VOYA INVESTMENT MANAGEMENT LLC |
$153887 |
15623 |
0.02% |
股份
|
| LMR Partners LLP |
$153227 |
15556 |
0.02% |
股份
|
| CITADEL ADVISORS LLC |
$144795 |
14700 |
0.02% |
买入期权
|
| BARTLETT & CO. WEALTH MANAGEMENT LLC |
$141348 |
14350 |
0.02% |
股份
|
| Shay Capital LLC |
$132118 |
13413 |
0.02% |
股份
|
| CITADEL ADVISORS LLC |
$131005 |
13300 |
0.02% |
卖出期权
|
| One68 Global Capital, LLC |
$128178 |
13013 |
0.02% |
股份
|
| MIRABELLA FINANCIAL SERVICES LLP |
$119914 |
12174 |
0.02% |
股份
|
| 360 Financial, Inc. |
$119412 |
12123 |
0.02% |
股份
|
| Creative Planning |
$115786 |
11755 |
0.02% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$112280 |
11399 |
0.02% |
股份
|
| Forum Financial Management, LP |
$107631 |
10927 |
0.02% |
股份
|
| CAPTRUST FINANCIAL ADVISORS |
$107513 |
10915 |
0.02% |
股份
|
| Duncan Williams Asset Management, LLC |
$107070 |
10870 |
0.02% |
股份
|
| ProShare Advisors LLC |
$105395 |
10700 |
0.02% |
股份
|
| Tower Research Capital LLC (TRC) |
$85153 |
8645 |
0.01% |
股份
|
| Legal & General Group Plc |
$78179 |
7937 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$73048 |
7416 |
0.01% |
股份
|
| OSAIC HOLDINGS, INC. |
$69442 |
7050 |
0.01% |
股份
|
| Arax Advisory Partners |
$60055 |
6097 |
0.01% |
股份
|
| ROYAL BANK OF CANADA |
$50000 |
5097 |
0.01% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$47270 |
4799 |
0.01% |
股份
|
| CWM, LLC |
$17621 |
3175 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$16223 |
1647 |
0.00% |
股份
|
| GAMMA Investing LLC |
$15002 |
1523 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$10943 |
1111 |
0.00% |
股份
|
| JONES FINANCIAL COMPANIES LLLP |
$4729 |
488 |
0.00% |
股份
|
| Torren Management, LLC |
$2792 |
503 |
0.00% |
股份
|
| Allworth Financial LP |
$2591 |
263 |
0.00% |
股份
|
| Truvestments Capital LLC |
$2266 |
230 |
0.00% |
股份
|
| Quarry LP |
$1143 |
116 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$1045 |
106 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$995 |
101 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$670 |
67994 |
0.00% |
股份
|
| Essential Partners LLC |
$660 |
67 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$552 |
56 |
0.00% |
股份
|
| Physician Wealth Advisors, Inc. |
$404 |
41 |
0.00% |
股份
|
| US BANCORP \DE\ |
$345 |
35 |
0.00% |
股份
|
| IFP Advisors, Inc |
$305 |
31 |
0.00% |
股份
|
| HARBOUR INVESTMENTS, INC. |
$296 |
30 |
0.00% |
股份
|
| SALEM INVESTMENT COUNSELORS INC |
$197 |
20 |
0.00% |
股份
|
| NATIONAL BANK OF CANADA /FI/ |
$148 |
15 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$138 |
14 |
0.00% |
股份
|
| Sunbelt Securities, Inc. |
$122 |
22 |
0.00% |
股份
|
| PNC Financial Services Group, Inc. |
$99 |
10 |
0.00% |
股份
|
| SJS Investment Consulting Inc. |
$69 |
7 |
0.00% |
股份
|
| JPL Wealth Management, LLC |
$60 |
6 |
0.00% |
股份
|
| Clearstead Advisors, LLC |
$50 |
5 |
0.00% |
股份
|
| FNY Investment Advisers, LLC |
$49 |
5000 |
0.00% |
股份
|