DYN Dyne Therapeutics, Inc. - Common Stock
$26.41
价格 · 八月 19, 2026
截至...的财报数据 七月 29, 2026
52周区间
$12–$27
94% of range
分析师评级
BUY
21 analysts
目标价
$39
+49% upside
P/E (TTM)
-7.6
ROE
-57.8%
净利润率
—
DYN 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围
价格
$26.41
市值
$4.36B
P/E (TTM)
-7.6
每股收益 (TTM)
$-3.47
营收 (TTM)
—
股息收益率
—
ROE
-57.8%
负债/权益
—
52周区间
$12 – $27
DYN 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图
Configure
10年表现 收入、净利润、利润率和每股收益趋势
营收与净利润
—
EPS
$-3.47
2021-12-31
→
2025-12-31
自由现金流
$-405M
2020-12-31
→
2025-12-31
利润率
—
估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜？
指标
5年趋势
DYN
同行中位数
P/E (TTM)
-7.6
13.2
P/B (市净率)
4.5
3.5
Price / FCF (股价/自由现金流)
-10.8
—
盈利能力 毛利率、营业利润率和净利率；股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)
指标
5年趋势
DYN
同行中位数
ROA
-47.5%
-42.2%
ROE
-57.8%
-52.8%
财务健康 债务、流动性、偿付能力 — 资产负债表强度
指标
5年趋势
DYN
同行中位数
Current Ratio (流动比率)
22.3
10.3
Quick Ratio (速动比率)
17.6
—
成长 营收、每股收益 (EPS) 和净利润增长：同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)
指标
5年趋势
DYN
同行中位数
资本效率 资产周转率、库存周转率、应收账款周转率
指标
5年趋势
DYN
同行中位数
DYN 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间
买入
21 位分析师
- 强烈买入 7 33.3%
- 买入 12 57.1%
- 持有 2 9.5%
- 卖出 0 0.0%
- 强烈卖出 0 0.0%
12个月价格目标
15 位分析师 · 2026-08-15
中位数
$40.00
现在
$26.41
最低
$17.00
最高
$50.00
中位数目标
$40.00
+51.5%
平均目标
$39.40
+49.2%
收益历史 每股收益实际值 vs 预估值，惊喜%，达标率，下次财报日期
平均惊喜
-0.06%
| 期间 | EPS Actual | EPS 预期 | 惊喜 |
|---|---|---|---|
| 2026年6月30日 | $-1.08 | $-0.76 | -0.32% |
| 2026年3月31日 | $-0.73 | $-0.78 | 0.05% |
| 2025年12月31日 | $-0.76 | $-0.78 | 0.02% |
| 2025年9月30日 | $-0.76 | $-0.85 | 0.09% |
| 2025年6月30日 | $-0.97 | $-0.96 | -0.01% |
| 2025年3月31日 | $-1.05 | $-0.89 | -0.16% |
同行比较（GICS 子行业） 关键指标与行业同行对比
| 股票代码 | 市值 | P/E | 营收同比增长 | 净利润率 | ROE | 毛利率 |
|---|---|---|---|---|---|---|
| DYN | $3.23B | -5.6 | — | — | -57.8% | — |
| CAI | $7.62B | -8.4 | 97.0% | -8.4% | -13.2% | — |
| PTCT | $6.19B | 9.8 | 114.5% | 39.4% | -331.5% | — |
| TVTX | $3.47B | -131.8 | 110.5% | -5.2% | -34.6% | — |
| ACAD | $4.55B | 11.6 | 11.9% | 36.5% | 38.1% | — |
| CELC | $4.81B | -26.3 | — | — | -244.3% | — |
| RLAY | $1.47B | -5.3 | 53.4% | -1800.6% | -44.9% | — |
| PBLS | — | — | — | — | — | — |
| TNGX | $1.20B | -10.2 | 48.3% | -162.8% | -42.2% | — |
完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表
损益表 10
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| R&D Expense | $398M | $281M | $211M | $143M | $121M | $45M | $11M | |
| SG&A Expense | $70M | $62M | $31M | $28M | $29M | $13M | $3M | |
| Operating Expenses | $468M | $344M | $242M | $171M | $150M | $59M | $14M | |
| Operating Income | $-468M | $-344M | $-242M | $-171M | $-150M | $-59M | $-14M | |
| Other Non-op | $22M | $26M | $6M | $3M | $734.0K | $-790.0K | $-1M | |
| Income Tax | $0 | $0 | $0 | · | · | · | · | |
| Net Income | $-446M | $-317M | $-236M | $-168M | $-149M | $-59M | $-15M | |
| EPS (Basic) | $-3.47 | $-3.37 | $-3.95 | $-3.23 | $-2.93 | · | · | |
| EPS (Diluted) | $-3.47 | $-3.37 | $-3.95 | $-3.23 | $-2.93 | · | · | |
| EBITDA | $-466M | $-342M | $-240M | $-169M | $-149M | $-58M | · |
资产负债表 20
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $893M | $435M | $122M | $172M | $201M | $301M | $15M | |
| Prepaid Expense | $16M | $17M | $6M | $10M | $6M | $4M | $127.0K | |
| Current Assets | $1.13B | $659M | $129M | $266M | $382M | $349M | $15M | |
| PP&E (Net) | $24M | $5M | $5M | $6M | $5M | $2M | $1M | |
| PP&E (Gross) | $33M | $12M | $10M | $10M | $7M | $3M | $2M | |
| Accum. Depreciation | $9M | $7M | $5M | $4M | $2M | $995.0K | $295.0K | |
| Other Non-current Assets | · | · | · | · | · | · | $191.0K | |
| Total Assets | $1.19B | $691M | $165M | $306M | $426M | $353M | $16M | |
| Accounts Payable | $8M | $7M | $23M | $5M | $4M | $3M | $1M | |
| Current Liabilities | $51M | $42M | $51M | $28M | $29M | $11M | $2M | |
| Capital Leases | $15M | $19M | $23M | $26M | $29M | $0 | · | |
| Total Liabilities | $215M | $61M | $74M | $54M | $57M | $11M | $2M | |
| Long-term Debt | $149M | $0 | · | · | · | · | · | |
| Common Stock | $16.0K | $10.0K | $6.0K | $6.0K | $6.0K | $5.0K | $1.0K | |
| Paid-in Capital | $2.37B | $1.58B | $724M | $650M | $597M | $422M | $6M | |
| Retained Earnings | $-1.40B | $-950M | $-633M | $-397M | $-228M | $-79M | $-20M | |
| AOCI | $475.0K | $6.0K | $0 | $-571.0K | $-269.0K | $-27.0K | · | |
| Stockholders' Equity | $972M | $630M | $91M | $252M | $368M | $342M | $14M | |
| Liabilities + Equity | $1.19B | $691M | $165M | $306M | $426M | $353M | $16M | |
| Shares Outstanding | 164,950,540 | 102,318,629 | 61,468,743 | 55,636,505 | 51,569,381 | 45,076,574 | 2,586,535 |
现金流 13
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| D&A | $2M | $2M | $2M | $2M | $1M | $700.0K | $271.0K | |
| Stock-based Comp | $46M | $46M | $20M | $15M | $18M | $7M | $26.0K | |
| Other Non-cash | $-5M | $-22M | $26M | $-2M | $11M | $6M | · | |
| Operating Cash Flow | $-403M | $-292M | $-188M | $-154M | $-120M | $-47M | $-12M | |
| CapEx | $2M | $2M | $729.0K | $3M | $4M | $1M | $2M | |
| Investing Cash Flow | $-29M | $-204M | $83M | $87M | $-138M | $-46M | $-2M | |
| Debt Issued | $148M | $0 | $0 | · | · | $10M | · | |
| Net Debt Issued | $148M | · | · | · | · | $10M | · | |
| Stock Issued | $141M | $98M | $52M | $37M | · | · | · | |
| Net Stock Activity | $141M | $98M | · | · | · | · | · | |
| Financing Cash Flow | $890M | $810M | $54M | $37M | $158M | $381M | $20M | |
| Net Change in Cash | $458M | $313M | $-51M | $-29M | $-100M | $289M | $7M | |
| Free Cash Flow | $-405M | $-295M | $-189M | $-157M | $-123M | $-48M | · |
盈利能力 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -47.5% | -74.1% | -100.1% | -45.9% | -38.3% | -32.1% | · | |
| ROE | -57.8% | -47.5% | -193.9% | -67.0% | -38.2% | -16.8% | · |
流动性与偿付能力 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 22.3 | 15.6 | 2.5 | 9.5 | 13.3 | 31.8 | · | |
| Quick Ratio | 17.6 | 10.3 | 2.4 | 6.1 | 7.0 | 27.4 | · |
估值 (TTM) 8
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-446M | $-317M | $-236M | $-168M | $-149M | $-59M | · | |
| Market Cap | $3.23B | $2.41B | $818M | $645M | $613M | $947M | · | |
| P/E | -5.6 | -7.0 | -3.4 | -3.6 | -4.1 | · | · | |
| P/B | 3.3 | 3.8 | 9.0 | 2.6 | 1.7 | 2.8 | · | |
| P / Tangible Book | 3.3 | 3.8 | 9.0 | 2.6 | 1.7 | 2.8 | · | |
| P / Cash Flow | -8.0 | -8.2 | -4.3 | -4.2 | -5.1 | -20.4 | · | |
| P / FCF | -8.0 | -8.2 | -4.3 | -4.1 | -5.0 | -19.9 | · | |
| Earnings Yield | -17.7% | -14.3% | -29.7% | -27.9% | -24.6% | · | · |
损益表 10
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $152M | $101M | $95M | $97M | $99M | $106M | $82M | $93M | $62M | $45M | $55M | $59M | $38M | $35M | $47M | $28M | |
| SG&A Expense | $29M | $24M | $21M | $17M | $17M | $16M | $15M | $13M | $10M | $25M | $7M | $8M | $8M | $8M | $6M | $8M | |
| Operating Expenses | $182M | $125M | $116M | $114M | $116M | $122M | $97M | $106M | $72M | $69M | $62M | $67M | $45M | $42M | $53M | $36M | |
| Operating Income | $-182M | $-125M | $-116M | $-114M | $-116M | $-122M | $-97M | $-106M | $-72M | $-69M | $-62M | $-67M | $-45M | $-42M | $-53M | $-36M | |
| Interest Expense | · | · | · | $3M | $94.0K | · | · | $0 | · | · | · | · | · | · | · | · | |
| Other Non-op | $3M | $4M | $4M | $6M | $5M | $7M | $8M | $9M | $7M | $4M | $2M | $2M | $1M | $894.0K | $451.0K | $200.0K | |
| Net Income | $-179M | $-121M | $-112M | $-108M | $-111M | $-115M | $-90M | $-97M | $-65M | $-66M | $-60M | $-65M | $-44M | $-41M | $-52M | $-36M | |
| EPS (Basic) | $-1.08 | $-0.73 | $-0.69 | $-0.76 | $-0.97 | $-1.05 | $-0.90 | $-0.96 | $-0.70 | $-0.81 | $-0.99 | $-1.08 | $-0.78 | $-0.80 | $-1.01 | $-0.69 | |
| EPS (Diluted) | $-1.08 | $-0.73 | $-0.69 | $-0.76 | $-0.97 | $-1.05 | $-0.90 | $-0.96 | $-0.70 | $-0.81 | $-0.99 | $-1.08 | $-0.78 | $-0.80 | $-1.01 | $-0.69 | |
| EBITDA | $-181M | $-125M | · | $-113M | $-115M | $-122M | · | $-105M | $-72M | $-69M | $-62M | $-66M | $-45M | $-42M | $-52M | $-35M |
资产负债表 19
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $676M | $753M | $893M | $574M | $485M | $472M | $435M | $532M | $608M | $272M | $130M | $168M | $181M | $145M | $136M | $148M | |
| Prepaid Expense | $39M | $49M | $16M | $14M | $14M | $12M | $17M | $13M | $13M | $35M | $10M | $5M | $11M | $10M | $6M | $21M | |
| Current Assets | $938M | $1.02B | $1.13B | $806M | $698M | $690M | $659M | $736M | $792M | $488M | $168M | $213M | $249M | $258M | $298M | $344M | |
| PP&E (Net) | $25M | $24M | $24M | $24M | $6M | $6M | $5M | $5M | $5M | $5M | $5M | $5M | $6M | $6M | $5M | $6M | |
| PP&E (Gross) | $34M | $33M | $33M | $32M | $13M | $13M | $12M | $11M | $11M | $10M | $10M | $10M | $10M | $9M | $8M | $8M | |
| Accum. Depreciation | $10M | $9M | $9M | $8M | $8M | $7M | $7M | $7M | $6M | $6M | $5M | $4M | $4M | $3M | $3M | $2M | |
| Total Assets | $994M | $1.08B | $1.19B | $867M | $729M | $721M | $691M | $769M | $826M | $522M | $205M | $251M | $289M | $300M | $340M | $388M | |
| Accounts Payable | $12M | $11M | $8M | $12M | $14M | $7M | $7M | $6M | $2M | $7M | $4M | $3M | $9M | $919.0K | $7M | $5M | |
| Current Liabilities | $78M | $51M | $51M | $60M | $41M | $34M | $42M | $43M | $30M | $22M | $30M | $20M | $22M | $23M | $26M | $23M | |
| Capital Leases | $15M | $14M | $15M | $16M | $17M | $18M | $19M | $20M | $21M | $22M | $24M | $24M | $25M | $27M | $27M | $28M | |
| Total Liabilities | $292M | $215M | $215M | $175M | $158M | $52M | $61M | $63M | $51M | $44M | $53M | $45M | $47M | $50M | $53M | $51M | |
| Long-term Debt | $199M | $149M | $149M | $99M | $99M | · | $0 | · | · | · | · | · | · | · | · | · | |
| Common Stock | $16.0K | $16.0K | $16.0K | $14.0K | $11.0K | $11.0K | $10.0K | $10.0K | $10.0K | $9.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | |
| Paid-in Capital | $2.40B | $2.38B | $2.37B | $1.98B | $1.75B | $1.73B | $1.58B | $1.57B | $1.54B | $1.18B | $718M | $713M | $683M | $608M | $605M | $601M | |
| Retained Earnings | $-1.70B | $-1.52B | $-1.40B | $-1.28B | $-1.18B | $-1.07B | $-950M | $-860M | $-763M | $-698M | $-566M | $-506M | $-441M | $-358M | $-316M | $-264M | |
| AOCI | $-353.0K | $-137.0K | $475.0K | $496.0K | $252.0K | $241.0K | $6.0K | $478.0K | $-240.0K | $-132.0K | $-13.0K | $-56.0K | $-203.0K | $-983.0K | $-1M | $-930.0K | |
| Stockholders' Equity | $702M | $865M | $972M | $692M | $571M | $669M | $630M | $706M | $775M | $478M | $152M | $207M | $242M | $250M | $287M | $336M | |
| Liabilities + Equity | $994M | $1.08B | $1.19B | $867M | $729M | $721M | $691M | $769M | $826M | $522M | $205M | $251M | $289M | $300M | $340M | $388M | |
| Shares Outstanding | 165,670,880 | 165,201,329 | 164,950,540 | 142,613,248 | 114,338,610 | 113,633,782 | 102,318,629 | 101,753,378 | 100,119,518 | 87,089,649 | 61,322,283 | 61,013,986 | 58,305,480 | 51,906,773 | 51,734,361 | 51,649,423 |
现金流 12
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $600.0K | $550.0K | $547.0K | $500.0K | $500.0K | $502.0K | $487.0K | $400.0K | $400.0K | $386.0K | $400.0K | $400.0K | $412.0K | $400.0K | $500.0K | $425.0K | |
| Stock-based Comp | $15M | $13M | $11M | $11M | $11M | $13M | $10M | $9M | $7M | $20M | $5M | $5M | $5M | $4M | $3M | $4M | |
| Other Non-cash | · | $-38M | · | · | · | $-4M | · | · | · | $-33M | · | · | $-8M | · | · | $-20M | |
| Operating Cash Flow | $-130M | $-145M | $-112M | $-91M | $-95M | $-106M | $-84M | $-75M | $-55M | $-79M | $-51M | $-56M | $-47M | $-43M | $-31M | $-51M | |
| CapEx | $2M | $221.0K | $484.0K | $395.0K | $60.0K | $981.0K | $1M | $253.0K | $857.0K | $191.0K | $167.0K | $250.0K | $230.0K | $886.0K | $261.0K | $1M | |
| Investing Cash Flow | $-5M | $-2M | $982.0K | $-38M | $7M | $1M | $-16M | $-19M | $11M | $-180M | $13M | $17M | $27M | $52M | $18M | $-2M | |
| Debt Issued | · | · | $49M | $0 | · | · | $0 | $0 | · | · | · | · | · | · | · | · | |
| Stock Issued | $0 | $0 | $0 | $0 | $0 | $141M | $0 | $0 | $24M | $74M | $0 | $24M | $28M | · | · | · | |
| Net Stock Activity | · | $0 | · | · | · | $141M | · | · | · | $74M | · | · | · | · | · | · | |
| Financing Cash Flow | $58M | $7M | $431M | $217M | $101M | $141M | $4M | $18M | $380M | $408M | $454.0K | $25M | $29M | $70.0K | $99.0K | $18.0K | |
| Net Change in Cash | $-77M | $-140M | $320M | $89M | $13M | $37M | $-97M | $-76M | $336M | $150M | $-37M | $-14M | $9M | $9M | $-12M | $-53M | |
| Free Cash Flow | · | $-145M | · | · | · | $-107M | · | · | · | $-79M | · | · | $-47M | · | · | $-52M |
盈利能力 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -20.7% | -13.4% | · | -13.2% | -14.3% | -18.6% | · | -19.9% | -12.1% | -16.2% | -23.8% | -21.9% | -13.1% | -10.8% | -13.0% | -8.1% | |
| ROE | -28.0% | -15.8% | · | -15.5% | -16.5% | -20.1% | · | -22.7% | -13.3% | -18.2% | -30.0% | -26.3% | -15.3% | -12.5% | -14.1% | -8.7% |
流动性与偿付能力 3
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 12.0 | 19.9 | · | 13.5 | 16.8 | 20.4 | · | 17.0 | 26.6 | 21.8 | 5.7 | 10.5 | 11.5 | 11.1 | 11.6 | 14.8 | |
| Quick Ratio | 8.7 | 14.7 | · | 9.6 | 11.7 | 13.9 | · | 12.3 | 20.4 | 12.2 | 4.4 | 8.3 | 8.4 | 6.2 | 5.3 | 6.4 | |
| Interest Coverage | · | · | · | -39.2 | -1231.8 | · | · | · | · | · | · | · | · | · | · | · |
估值 (TTM) 8
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-518M | $-455M | · | $-431M | $-388M | $-343M | · | $-288M | $-256M | $-235M | $-211M | $-203M | $-173M | $-172M | $-160M | $-133M | |
| Market Cap | $3.68B | $3.00B | · | $1.80B | $1.09B | $1.19B | · | $3.65B | $3.53B | $2.47B | $549M | $686M | $672M | $659M | $355M | $498M | |
| P/E | -6.3 | -5.2 | · | -3.4 | -2.6 | -3.0 | · | -10.4 | -9.9 | -7.8 | -2.5 | -3.1 | -3.5 | -3.8 | -2.2 | · | |
| P/B | 5.2 | 3.5 | · | 2.6 | 1.9 | 1.8 | · | 5.2 | 4.6 | 5.2 | 3.6 | 3.3 | 2.8 | 2.6 | 1.2 | 1.5 | |
| P / Tangible Book | 5.2 | 3.5 | · | 2.6 | 1.9 | 1.8 | · | 5.2 | 4.6 | 5.2 | 3.6 | 3.3 | 2.8 | 2.6 | 1.2 | 1.5 | |
| P / Cash Flow | · | -20.7 | · | · | · | -11.2 | · | · | · | -31.5 | · | · | -14.3 | · | · | -9.8 | |
| P / FCF | · | -20.6 | · | · | · | -11.1 | · | · | · | -31.4 | · | · | -14.2 | · | · | -9.5 | |
| Earnings Yield | -15.9% | -19.4% | · | -29.6% | -38.7% | -33.7% | · | -9.6% | -10.1% | -12.9% | -40.7% | -32.6% | -28.5% | -26.2% | -45.3% | · |
财务报表 损益表、资产负债表、现金流量表 — 年度，近5年
损益表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 净收入 | $-446M | $-317M | $-236M | $-168M | $-149M |
| 稀释后每股收益 (EPS) | $-3.47 | $-3.37 | $-3.95 | $-3.23 | $-2.93 |
资产负债表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 流动比率 | 22.3 | 15.6 | 2.5 | 9.5 | 13.3 |
| 速动比率 | 17.6 | 10.3 | 2.4 | 6.1 | 7.0 |
现金流
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 自由现金流 | $-405M | $-295M | $-189M | $-157M | $-123M |
最新新闻 提及该公司的近期头条新闻
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机构持有人 (13F) 261 家申报者 · $2.5B 总计 · 截至 2026年6月30日
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
机构活动 — Q2 2026 与上一季度对比
| 新仓位 | 已退出持仓 | 增加 | 减少 | 净股数变动 |
|---|---|---|---|---|
| 54 (+19 与上一季度对比) | 27 (-14 与上一季度对比) | 87 (-11 与上一季度对比) | 70 (+7 与上一季度对比) | +15.5M |
与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天，外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过，优先显示最近一个已完整报告的季度对。
| 机构 | 价值 | 股份 | % 已追踪的13F | 类型 |
|---|---|---|---|---|
| STATE STREET CORP | $165648021 | 7458263 | 6.74% | 股份 |
| FMR LLC | $160201907 | 7213053 | 6.52% | 股份 |
| Orbis Allan Gray Ltd | $155111575 | 6983862 | 6.31% | 股份 |
| Atlas Venture Life Science Advisors, LLC | $151030199 | 6800099 | 6.14% | 股份 |
| VANGUARD CAPITAL MANAGEMENT LLC | $140166621 | 6310969 | 5.70% | 股份 |
| TCG Crossover Management, LLC | $102502348 | 4615144 | 4.17% | 股份 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $89915586 | 4048428 | 3.66% | 股份 |
| Vestal Point Capital, LP | $74958750 | 3375000 | 3.05% | 股份 |
| ORBIMED ADVISORS LLC | $71864542 | 3235684 | 2.92% | 股份 |
| GEODE CAPITAL MANAGEMENT, LLC | $71309878 | 3209934 | 2.90% | 股份 |
| Frazier Life Sciences Management, L.P. | $70029951 | 3153082 | 2.85% | 股份 |
| ARMISTICE CAPITAL, LLC | $68567289 | 3087226 | 2.79% | 股份 |
| PERCEPTIVE ADVISORS LLC | $59727909 | 2689235 | 2.43% | 股份 |
| Logos Global Management LP | $56635500 | 2550000 | 2.30% | 股份 |
| Venrock Adviser, LLC | $48282608 | 2173913 | 1.96% | 股份 |
| Siren, L.L.C. | $47287866 | 2129125 | 1.92% | 股份 |
| MPM BIOIMPACT LLC | $42689686 | 1922093 | 1.74% | 股份 |
| GOLDMAN SACHS GROUP INC | $41625071 | 1874159 | 1.69% | 股份 |
| DIMENSIONAL FUND ADVISORS LP | $40865556 | 1839962 | 1.66% | 股份 |
| Sofinnova Investments, Inc. | $36832709 | 1658384 | 1.50% | 股份 |
| Palo Alto Investors LP | $36591441 | 1647521 | 1.49% | 股份 |
| Vivo Capital, LLC | $34591320 | 1557466 | 1.41% | 股份 |
| Aberdeen Group plc | $34190829 | 1539434 | 1.39% | 股份 |
| Deep Track Capital, LP | $33315000 | 1500000 | 1.35% | 股份 |
| BANK OF AMERICA CORP /DE/ | $31725719 | 1428443 | 1.29% | 股份 |
| FCPM III SERVICES B.V. | $31679678 | 1426370 | 1.29% | 股份 |
| Polar Capital Holdings Plc | $28580072 | 1286811 | 1.16% | 股份 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $26700929 | 1202203 | 1.09% | 股份 |
| CITADEL ADVISORS LLC | $25407307 | 1143958 | 1.03% | 股份 |
| Saturn V Capital Management LP | $23486920 | 1057493 | 0.96% | 股份 |
| VANGUARD FIDUCIARY TRUST CO | $21964557 | 988949 | 0.89% | 股份 |
| NOVO HOLDINGS A/S | $21330351 | 960394 | 0.87% | 股份 |
| Rock Springs Capital Management LP | $20925240 | 942154 | 0.85% | 股份 |
| BRAIDWELL LP | $20468692 | 921598 | 0.83% | 股份 |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $19414605 | 874138 | 0.79% | 股份 |
| BAKER BROS. ADVISORS LP | $18066702 | 813449 | 0.73% | 股份 |
| SAMLYN CAPITAL, LLC | $14875658 | 669773 | 0.61% | 股份 |
| Artisan Partners Limited Partnership | $14653847 | 659786 | 0.60% | 股份 |
| TD Asset Management Inc | $12173568 | 548112 | 0.50% | 股份 |
| ALGERT GLOBAL LLC | $11244323 | 506273 | 0.46% | 股份 |
| MILLENNIUM MANAGEMENT LLC | $9591389 | 431850 | 0.39% | 股份 |
| Clearbridge Investments, LLC | $9220070 | 415131 | 0.37% | 股份 |
| ArrowMark Colorado Holdings LLC | $8822278 | 397221 | 0.36% | 股份 |
| MPM ASSET MANAGEMENT LLC | $8632056 | 682376 | 0.35% | 股份 |
| WASATCH ADVISORS LP | $8043701 | 443668 | 0.33% | 股份 |
| RENAISSANCE TECHNOLOGIES LLC | $8008304 | 360572 | 0.33% | 股份 |
| Tetragon Partners GP Ltd | $7921352 | 356657 | 0.32% | 股份 |
| NEW YORK STATE COMMON RETIREMENT FUND | $7905716 | 355953 | 0.32% | 股份 |
| Granahan Investment Management, LLC | $7519529 | 338565 | 0.31% | 股份 |
| University of Wisconsin Foundation | $6964146 | 313559 | 0.28% | 股份 |
| MOORE CAPITAL MANAGEMENT, LP | $6791685 | 305794 | 0.28% | 股份 |
| Squarepoint Ops LLC | $6664644 | 300074 | 0.27% | 股份 |
| Fisher Asset Management, LLC | $6629795 | 298505 | 0.27% | 股份 |
| AMERIPRISE FINANCIAL INC | $6625622 | 298317 | 0.27% | 股份 |
| RAYMOND JAMES FINANCIAL INC | $6468951 | 291263 | 0.26% | 股份 |
| Ensign Peak Advisors, Inc | $6434903 | 289730 | 0.26% | 股份 |
| Alyeska Investment Group, L.P. | $5447624 | 245278 | 0.22% | 股份 |
| Catalio Capital Management, LP | $5439873 | 244929 | 0.22% | 股份 |
| Swiss National Bank | $5152720 | 232000 | 0.21% | 股份 |
| SPHERA FUNDS MANAGEMENT LTD. | $4432983 | 199594 | 0.18% | 股份 |
| SummitTX Capital, L.P. | $4323021 | 194643 | 0.18% | 股份 |
| RHUMBLINE ADVISERS | $4082158 | 183799 | 0.17% | 股份 |
| CITIGROUP INC | $3998733 | 180042 | 0.16% | 股份 |
| HighVista Strategies LLC | $3819254 | 171961 | 0.16% | 股份 |
| ALPS ADVISORS INC | $3710891 | 167082 | 0.15% | 股份 |
| Y-Intercept (Hong Kong) Ltd | $3469269 | 156203 | 0.14% | 股份 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $3467781 | 156136 | 0.14% | 股份 |
| AXXCESS WEALTH MANAGEMENT, LLC | $3448547 | 155270 | 0.14% | 股份 |
| Darwin Wealth Management, LLC | $3448546 | 155270 | 0.14% | 股份 |
| Aegis Wealth Management LLC | $3332166 | 150030 | 0.14% | 股份 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $3331500 | 150000 | 0.14% | 股份 |
| Woodline Partners LP | $3317907 | 149388 | 0.13% | 股份 |
| BlackRock, Inc. | $3223182 | 145123 | 0.13% | 股份 |
| Bank of New York Mellon Corp | $3129789 | 140918 | 0.13% | 股份 |
| ALLIANCEBERNSTEIN L.P. | $3119810 | 172080 | 0.13% | 股份 |
| Schonfeld Strategic Advisors LLC | $2992841 | 134752 | 0.12% | 股份 |
| XTX Topco Ltd | $2793707 | 125786 | 0.11% | 股份 |
| Jain Global LLC | $2583934 | 116341 | 0.11% | 股份 |
| Rafferty Asset Management, LLC | $2556415 | 115102 | 0.10% | 股份 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2532090 | 139663 | 0.10% | 股份 |
| MORGAN STANLEY | $2460571 | 110786 | 0.10% | 股份 |
| AXA Investment Managers S.A. | $2064872 | 163231 | 0.08% | 股份 |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | $1933798 | 87069 | 0.08% | 股份 |
| JANUS HENDERSON GROUP PLC | $1810516 | 99863 | 0.07% | 股份 |
| VANGUARD ASSET MANAGEMENT, Ltd | $1804296 | 81238 | 0.07% | 股份 |
| MetLife Investment Management, LLC | $1771803 | 79775 | 0.07% | 股份 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1746195 | 78622 | 0.07% | 股份 |
| FIFTH THIRD BANCORP | $1684826 | 75859 | 0.07% | 股份 |
| CIBC WORLD MARKET INC. | $1683140 | 75783 | 0.07% | 股份 |
| STATE OF WISCONSIN INVESTMENT BOARD | $1548081 | 69702 | 0.06% | 股份 |
| ENVESTNET ASSET MANAGEMENT INC | $1478808 | 66583 | 0.06% | 股份 |
| VANGUARD GROUP INC | $1433904 | 73308 | 0.06% | 股份 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1395321 | 62824 | 0.06% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1390346 | 62600 | 0.06% | 卖出期权 |
| JANE STREET GROUP, LLC | $1377020 | 62000 | 0.06% | 卖出期权 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $1309213 | 58947 | 0.05% | 股份 |
| PROFUND ADVISORS LLC | $1306170 | 58810 | 0.05% | 股份 |
| Invesco Ltd. | $1212555 | 54595 | 0.05% | 股份 |
| VICTORY CAPITAL MANAGEMENT INC | $1210400 | 54498 | 0.05% | 股份 |
| Vanguard Global Advisers, LLC | $1202383 | 54137 | 0.05% | 股份 |
公司内部人士 26 位内幕人士 · 7 位高管 · 10 位董事
| 内部人士 | 角色 | 上次活动 | 持股数量 | 买入 12个月 | 卖出 12个月 | 净额 12个月 |
|---|---|---|---|---|---|---|
| Joshua T Brumm | CEO & President | 2024年3月11日 M | 537998 | 0 | 0 | $0 |
| Susanna Gatti High | Chief Operating Officer | 2024年9月18日 S | 131636 | 0 | 0 | $0 |
| Oxana Beskrovnaya | Chief Scientific Officer | 2025年3月11日 S | 195840 | 0 | 0 | $0 |
| Richard William Scalzo | SVP, Head of Finance & Admin. | 2025年3月11日 S | 122330 | 0 | 0 | $0 |
| Wildon Farwell | Chief Medical Officer | 2024年8月19日 S | 143222 | 0 | 0 | $0 |
| Jonathan Mcneill | Chief Business Officer | 2024年8月19日 S | 132106 | 0 | 0 | $0 |
| Romesh Subramanian | Chief Scientific Officer | 2020年9月16日 A | 566249 | 0 | 0 | $0 |
| Dirk Kersten | 董事 | 2026年7月27日 S | 3586796 | 0 | 19 | $-38570974 |
| Barry E Greene | 董事 | 2026年6月22日 A | — | 0 | 0 | $0 |
| Carlo Incerti | 董事 | 2026年6月5日 A | 0 | 0 | 0 | $0 |
| Catherine Stehman-Breen | 董事 | 2026年6月5日 A | 115713 | 0 | 0 | $0 |
| David Charles Lubner | 董事 | 2026年6月5日 A | 0 | 0 | 0 | $0 |
| Brian S Posner | 董事 | 2026年6月5日 A | 24500 | 7 | 0 | $274840 |
| Edward Hurwitz | 董事 | 2026年6月5日 A | 91081 | 0 | 0 | $0 |
| Vikram Karnani | 董事 | 2025年12月22日 A | — | 0 | 0 | $0 |
| Lawrence Otto Klein | 董事 | 2022年7月5日 A | 10725 | 0 | 0 | $0 |
| Atlas Venture Fund XI, L.P. | 10% 所有者 | 2021年7月13日 J | 7326117 | 0 | 0 | $0 |
| CureDuchenne Ventures, LLC | 10% 所有者 | 2020年9月21日 C | 602972 | 0 | 0 | $0 |
| Forbion Capital Fund IV Cooperatief U.A. | 10% 所有者 | 2020年9月21日 C | 6131079 | 0 | 0 | $0 |
| Logos Global Management LP | 10% 所有者 | 2020年9月21日 C | 1504392 | 0 | 0 | $0 |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | 10% 所有者 | 2020年9月21日 C | 1608785 | 0 | 0 | $0 |
| Jason P Rhodes | — | 2026年8月14日 S | 428946 | 0 | 31 | $-99402433 |
| Johanna Friedl-Naderer | — | 2026年8月13日 S | 153982 | 0 | 7 | $-31766 |
| Douglas Kerr | — | 2026年8月13日 S | 167599 | 0 | 7 | $-176412 |
| Erick Lucera | — | 2026年8月13日 S | 119766 | 0 | 4 | $-228675 |
| John Cox | — | 2026年8月13日 S | 363165 | 0 | 5 | $-336865 |
来自SEC表格3/4/5申报的内部人士；净额=仅公开市场买卖
激进投资者及 5%+ 股东 1 持仓
提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权，意图影响发行人（激进股东持股、董事会活动、并购）。每一行显示该申报人持仓的最新已知状态。
| 申报人 | 已申报 | 持股 | 状态 | 目的 | 申报 |
|---|---|---|---|---|---|
| Vida Ventures II, LLC, Vida Ventures II-A, LLC, VV Manager II, LLC ×2 申报 | 2023年2月10日 | — | 初始申报 | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF持仓 由 52 只交易所交易基金持有
权重仅反映直接股权持仓（N-PORT）；杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。
| 基金 | 权重 | 单位 | 截至 | 来源 |
|---|---|---|---|---|
| IBRN · iShares Trust | 3.47% | 10352 SH | 2026年8月8日 | 每日 |
| BBC · ETFis Series Trust I | 0.67% | 14322 NS | 2026年4月30日 | N-PORT |
| JDOC · J.P. Morgan Exchange-Traded Fund ... | 0.67% | 4266 NS | 2026年4月30日 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0.67% | 196941 NS | 2026年4月30日 | N-PORT |
| IBB · iShares Trust | 0.30% | 1099711 SH | 2026年8月8日 | 每日 |
| IBBQ · Invesco Exchange-Traded Fund Trus... | 0.30% | 8997 SH | 2026年8月8日 | 每日 |
| ESSC · Strategy Shares | 0.18% | 2581 NS | 2026年4月30日 | N-PORT |
| IWN · iShares Trust | 0.16% | 919017 SH | 2026年8月8日 | 每日 |
| BIB · ProShares Trust | 0.16% | 6087 NS | 2026年5月31日 | N-PORT |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0.13% | 77375 SH | 2026年8月8日 | 每日 |
| BBSC · J.P. Morgan Exchange-Traded Fund ... | 0.12% | 51630 NS | 2026年4月30日 | N-PORT |
| IWM · iShares Trust | 0.12% | 3833065 SH | 2026年8月8日 | 每日 |
| BKSE · BNY Mellon ETF Trust | 0.10% | 4423 NS | 2026年4月30日 | N-PORT |
| ISCG · iShares Trust | 0.09% | 36532 SH | 2026年8月8日 | 每日 |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.09% | 784894 SH | 2026年8月8日 | 每日 |
| IWO · iShares Trust | 0.08% | 463505 SH | 2026年8月8日 | 每日 |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.08% | 82893 SH | 2026年8月8日 | 每日 |
| ESML · iShares Trust | 0.08% | 84297 SH | 2026年8月8日 | 每日 |
| RSSL · Global X Funds | 0.07% | 57752 NS | 2026年4月30日 | N-PORT |
| ITWO · ProShares Trust | 0.06% | 6271 NS | 2026年5月31日 | N-PORT |
| ISCB · iShares Trust | 0.06% | 6733 SH | 2026年8月8日 | 每日 |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.06% | 50849 SH | 2026年8月8日 | 每日 |
| SCHA · SCHWAB STRATEGIC TRUST | 0.06% | 688953 NS | 2026年5月31日 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0.05% | 47064 SH | 2026年8月8日 | 每日 |
| DFAS · Dimensional ETF Trust | 0.05% | 390218 NS | 2026年4月30日 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.04% | 1689620 SH | 2026年8月8日 | 每日 |
| VHT · VANGUARD WORLD FUND | 0.04% | 347244 SH | 2026年8月8日 | 每日 |
| ISCV · iShares Trust | 0.04% | 10732 SH | 2026年8月8日 | 每日 |
| UWM · ProShares Trust | 0.04% | 4905 NS | 2026年5月31日 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0.03% | 53716 NS | 2026年4月30日 | N-PORT |
| WSML · iShares Trust | 0.03% | 8466 SH | 2026年8月8日 | 每日 |
| VBR · VANGUARD INDEX FUNDS | 0.03% | 1020875 SH | 2026年8月8日 | 每日 |
| URTY · ProShares Trust | 0.03% | 4964 NS | 2026年5月31日 | N-PORT |
| TILT · FlexShares Trust | 0.02% | 25564 NS | 2026年4月30日 | N-PORT |
| VB · VANGUARD INDEX FUNDS | 0.02% | 1607020 SH | 2026年8月8日 | 每日 |
| SMLF · iShares Trust | 0.02% | 32751 SH | 2026年8月8日 | 每日 |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0.01% | 4701 NS | 2026年5月31日 | N-PORT |
| HDG · ProShares Trust | 0.01% | 125 NS | 2026年5月31日 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0.01% | 44010 NS | 2026年5月31日 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0.01% | 11272 NS | 2026年5月31日 | N-PORT |
| DCOR · Dimensional ETF Trust | 0.01% | 9076 NS | 2026年4月30日 | N-PORT |
| ITOT · iShares Trust | 0.01% | 199812 SH | 2026年8月8日 | 每日 |
| IWV · iShares Trust | 0.01% | 38879 SH | 2026年8月8日 | 每日 |
| DFAC · Dimensional ETF Trust | 0.00% | 123282 NS | 2026年4月30日 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0.00% | 84436 NS | 2026年5月31日 | N-PORT |
| DFAU · Dimensional ETF Trust | 0.00% | 21333 NS | 2026年4月30日 | N-PORT |
| DXUV · Dimensional ETF Trust | 0.00% | 720 NS | 2026年4月30日 | N-PORT |
| DFUS · Dimensional ETF Trust | 0.00% | 33452 NS | 2026年4月30日 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0.00% | 5252 NS | 2026年5月31日 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 4473029 SH | 2026年8月8日 | 每日 |