EWTX Edgewise Therapeutics, Inc. - Common Stock
$46.22
价格 · 八月 19, 2026
截至...的财报数据 八月 6, 2026
52周区间
$14–$48
94% of range
分析师评级
BUY
19 analysts
目标价
$51
+11% upside
P/E (TTM)
-28.7
ROE
-30.2%
净利润率
—
EWTX 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围
价格
$46.22
市值
$4.97B
P/E (TTM)
-28.7
每股收益 (TTM)
$-1.63
营收 (TTM)
—
股息收益率
—
ROE
-30.2%
负债/权益
—
52周区间
$14 – $48
EWTX 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图
Configure
10年表现 收入、净利润、利润率和每股收益趋势
营收与净利润
—
EPS
$-1.63
2020-12-31
→
2025-12-31
自由现金流
$-144M
2021-12-31
→
2025-12-31
利润率
—
估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜？
指标
5年趋势
EWTX
同行中位数
P/E (TTM)
-28.7
38.7
P/B (市净率)
9.5
3.8
Price / FCF (股价/自由现金流)
-34.5
—
盈利能力 毛利率、营业利润率和净利率；股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)
指标
5年趋势
EWTX
同行中位数
ROA
-32.3%
-6.4%
ROE
-30.2%
-16.8%
ROIC
-36.6%
—
财务健康 债务、流动性、偿付能力 — 资产负债表强度
指标
5年趋势
EWTX
同行中位数
Current Ratio (流动比率)
19.9
12.8
Quick Ratio (速动比率)
2.2
—
成长 营收、每股收益 (EPS) 和净利润增长：同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)
指标
5年趋势
EWTX
同行中位数
资本效率 资产周转率、库存周转率、应收账款周转率
指标
5年趋势
EWTX
同行中位数
EWTX 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间
买入
19 位分析师
- 强烈买入 7 36.8%
- 买入 9 47.4%
- 持有 3 15.8%
- 卖出 0 0.0%
- 强烈卖出 0 0.0%
12个月价格目标
13 位分析师 · 2026-08-18
中位数
$52.00
现在
$46.22
最低
$36.00
最高
$66.00
中位数目标
$52.00
+12.5%
平均目标
$51.15
+10.7%
收益历史 每股收益实际值 vs 预估值，惊喜%，达标率，下次财报日期
平均惊喜
0.01%
| 期间 | EPS Actual | EPS 预期 | 惊喜 |
|---|---|---|---|
| 2026年6月30日 | $-0.53 | $-0.48 | -0.05% |
| 2026年3月31日 | $-0.46 | $-0.50 | 0.04% |
| 2025年12月31日 | $-0.47 | $-0.44 | -0.03% |
| 2025年9月30日 | $-0.39 | $-0.41 | 0.02% |
| 2025年6月30日 | $-0.34 | $-0.42 | 0.08% |
| 2025年3月31日 | $-0.43 | $-0.44 | 0.01% |
同行比较（GICS 子行业） 关键指标与行业同行对比
| 股票代码 | 市值 | P/E | 营收同比增长 | 净利润率 | ROE | 毛利率 |
|---|---|---|---|---|---|---|
| EWTX | $2.64B | -15.2 | — | — | -30.2% | — |
| BLTE | — | — | — | — | — | — |
| DFTX | $1.32B | -6.5 | 212.0% | — | -71.0% | — |
| AMRX | — | 57.3 | 8.1% | 2.4% | -80.0% | 36.9% |
| LGND | $3.74B | 30.8 | 60.4% | 46.4% | 13.5% | — |
| MANE | — | — | — | — | 82.6% | — |
| INDV | — | 21.9 | 4.3% | 17.0% | -118.3% | 80.2% |
| ELVN | $915M | -8.4 | — | — | -21.9% | — |
| AMLX | $1.33B | -7.9 | -77.1% | — | -61.2% | — |
| GPCR | $14.78B | -86.9 | — | — | -12.3% | — |
| OGN | $1.87B | 10.0 | -2.9% | 3.0% | 25.2% | 53.3% |
完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表
损益表 12
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $151M | $127M | $91M | $54M | $32M | $15M | |
| SG&A Expense | $40M | $32M | $23M | $18M | $11M | $2M | |
| Operating Expenses | $191M | $159M | $114M | $72M | $43M | $17M | |
| Operating Income | $-191M | $-159M | $-114M | $-72M | $-43M | $-17M | |
| Pretax Income | $-168M | $-134M | $-100M | · | · | · | |
| Income Tax | $4.0K | $3.0K | $4.0K | $0 | $0 | · | |
| Net Income | $-168M | $-134M | $-100M | $-68M | $-43M | $-17M | |
| EPS (Basic) | $-1.63 | $-1.45 | $-1.57 | $-1.26 | $-1.14 | $-23.17 | |
| EPS (Diluted) | $-1.63 | $-1.45 | $-1.57 | $-1.26 | $-1.14 | $-23.17 | |
| Shares (Basic) | 102,930,744 | 92,414,626 | 63,723,600 | 53,593,753 | 37,526,332 | 739,004 | |
| Shares (Diluted) | 102,930,744 | 92,414,626 | 63,723,600 | 53,593,753 | 37,526,332 | 739,004 | |
| EBITDA | $-191M | $-159M | $-114M | $-72M | $-43M | · |
资产负债表 21
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $61M | $42M | $86M | $22M | $16M | $105M | |
| Prepaid Expense | $13M | $5M | $9M | $5M | $3M | $551.0K | |
| Current Assets | $543M | $475M | $327M | $357M | $284M | $130M | |
| PP&E (Net) | $8M | $10M | $10M | $9M | $912.0K | $516.0K | |
| PP&E (Gross) | $15M | $14M | $13M | $10M | $2M | $946.0K | |
| Accum. Depreciation | $7M | $5M | $3M | $1M | $702.0K | $430.0K | |
| Other Non-current Assets | · | $262.0K | $348.0K | $251.0K | $548.0K | $975.0K | |
| Total Assets | $553M | $487M | $340M | $367M | $285M | $131M | |
| Accounts Payable | $6M | $6M | $4M | $6M | $4M | $2M | |
| Accrued Liabilities | $8M | $7M | $6M | $6M | $4M | $2M | |
| Current Liabilities | $27M | $24M | $17M | $17M | $11M | $4M | |
| Capital Leases | $3M | $4M | $4M | $4M | · | · | |
| Other Non-current Liabilities | · | · | · | · | $329.0K | · | |
| Total Liabilities | $30M | $28M | $21M | $20M | $11M | $4M | |
| Common Stock | $10.0K | $9.0K | $7.0K | $6.0K | $5.0K | · | |
| Paid-in Capital | $1.07B | $837M | $563M | $493M | $352M | $727.0K | |
| Retained Earnings | $-546M | $-379M | $-245M | $-145M | $-77M | $-34M | |
| AOCI | $677.0K | $420.0K | $99.0K | $-1M | $-514.0K | · | |
| Stockholders' Equity | $522M | $459M | $319M | $347M | $274M | $-33M | |
| Liabilities + Equity | $553M | $487M | $340M | $367M | $285M | $131M | |
| Shares Outstanding | 106,249,579 | 94,838,466 | 70,453,342 | 63,257,376 | 49,500,308 | 1,009,479 |
现金流 9
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Stock-based Comp | $35M | $25M | $18M | $11M | $4M | $354.0K | |
| Operating Cash Flow | $-144M | $-109M | $-92M | $-53M | $-34M | $-15M | |
| CapEx | $256.0K | $1M | $6M | $6M | $668.0K | $203.0K | |
| Investing Cash Flow | $-33M | $-185M | $103M | $-71M | $-242M | $-24M | |
| Stock Issued | $187M | $239M | $53M | $129M | · | · | |
| Net Stock Activity | $187M | $239M | $53M | $129M | · | · | |
| Financing Cash Flow | $196M | $249M | $53M | $130M | $186M | $120M | |
| Net Change in Cash | $19M | $-44M | $64M | $6M | $-89M | $81M | |
| Free Cash Flow | $-144M | $-110M | $-98M | $-58M | $-34M | · |
盈利能力 3
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -32.3% | -32.4% | -28.3% | -20.7% | -20.6% | · | |
| ROE | -30.2% | -28.2% | -32.9% | -19.1% | -15.3% | · | |
| ROIC | -36.6% | · | · | · | · | · |
流动性与偿付能力 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 19.9 | 19.9 | 19.5 | 21.5 | 27.0 | · | |
| Quick Ratio | 2.2 | 1.7 | 5.1 | 1.3 | 1.5 | · |
估值 (TTM) 8
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-168M | $-134M | $-100M | $-68M | $-43M | · | |
| Market Cap | $2.64B | $2.53B | $771M | $566M | $756M | · | |
| P/E | -15.2 | -18.4 | -7.0 | -7.1 | -13.4 | · | |
| P/B | 5.0 | 5.5 | 2.4 | 1.6 | 2.8 | · | |
| P / Tangible Book | 5.0 | 5.5 | 2.4 | 1.6 | 2.8 | · | |
| P / Cash Flow | -18.3 | -23.2 | -8.4 | -10.7 | -22.6 | · | |
| P / FCF | -18.3 | -22.9 | -7.9 | -9.7 | -22.1 | · | |
| Earnings Yield | -6.6% | -5.4% | -14.3% | -14.1% | -7.5% | · |
损益表 10
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $48M | $43M | $44M | $37M | $34M | $37M | $36M | $32M | $31M | $28M | $24M | $20M | $20M | $17M | $14M | $12M | |
| SG&A Expense | $14M | $11M | $12M | $9M | $9M | $9M | $9M | $8M | $7M | $7M | $6M | $6M | $6M | $5M | $4M | $4M | |
| Operating Expenses | $62M | $54M | $56M | $47M | $43M | $46M | $46M | $40M | $38M | $35M | $29M | $25M | $26M | $22M | $18M | $16M | |
| Operating Income | $-62M | $-54M | $-56M | $-47M | $-43M | $-46M | $-46M | $-40M | $-38M | $-35M | $-29M | $-25M | $-26M | $-22M | $-18M | $-16M | |
| Net Income | $-57M | $-49M | $-50M | $-41M | $-36M | $-41M | $-40M | $-34M | $-31M | $-29M | $-26M | $-21M | $-23M | $-19M | $-17M | $-16M | |
| EPS (Basic) | $-0.53 | $-0.46 | $-0.47 | $-0.39 | $-0.34 | $-0.43 | $-0.42 | $-0.36 | $-0.34 | $-0.33 | $-0.41 | $-0.34 | $-0.36 | $-0.30 | $-0.34 | $-0.32 | |
| EPS (Diluted) | $-0.53 | $-0.46 | $-0.47 | $-0.39 | $-0.34 | $-0.43 | $-0.42 | $-0.36 | $-0.34 | $-0.33 | $-0.41 | $-0.34 | $-0.36 | $-0.30 | $-0.34 | $-0.32 | |
| Shares (Basic) | 107,669,774 | 107,116,709 | -202,632,581 | 105,492,779 | 104,940,493 | 95,130,053 | -182,481,383 | 93,813,346 | 93,515,356 | 87,567,307 | 63,459,560 | 63,380,430 | 63,265,800 | -97,418,492 | 51,844,904 | 49,622,752 | |
| Shares (Diluted) | 107,669,774 | 107,116,709 | -202,632,581 | 105,492,779 | 104,940,493 | 95,130,053 | -182,481,383 | 93,813,346 | 93,515,356 | 87,567,307 | 63,459,560 | 63,380,430 | 63,265,800 | -97,418,492 | 51,844,904 | 49,622,752 | |
| EBITDA | $-62M | $-54M | · | $-47M | $-43M | $-46M | · | $-40M | $-38M | $-35M | $-29M | $-25M | $-26M | · | $-18M | $-16M |
资产负债表 24
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $72M | $33M | $61M | $46M | $43M | $50M | $42M | $45M | $43M | $30M | $33M | $32M | $48M | $22M | $110M | $18M | |
| Prepaid Expense | $6M | $10M | $13M | $11M | $9M | $7M | $5M | $7M | $8M | $9M | $8M | $7M | $5M | $5M | $5M | $5M | |
| Current Assets | $472M | $510M | $543M | $574M | $603M | $443M | $475M | $499M | $519M | $541M | $298M | $317M | $333M | $357M | $370M | $253M | |
| PP&E (Net) | $7M | $7M | $8M | $8M | $9M | $9M | $10M | $10M | $10M | $10M | $11M | $11M | $10M | $9M | $5M | $2M | |
| PP&E (Gross) | $15M | $15M | $15M | $14M | $14M | $14M | $14M | $14M | $13M | $13M | $13M | $13M | $12M | $10M | $6M | $3M | |
| Accum. Depreciation | $8M | $7M | $7M | $6M | $6M | $5M | $5M | $4M | $4M | $3M | $2M | $2M | $1M | $1M | $977.0K | $882.0K | |
| Other Non-current Assets | · | · | · | · | · | $695.0K | $262.0K | $262.0K | $262.0K | · | $467.0K | $419.0K | $251.0K | $251.0K | $264.0K | $447.0K | |
| Total Assets | $480M | $519M | $553M | $583M | $613M | $454M | $487M | $511M | $532M | $554M | $311M | $331M | $346M | $367M | $377M | $257M | |
| Accounts Payable | $5M | $7M | $6M | $6M | $8M | $9M | $6M | $6M | $7M | $5M | $5M | $4M | $4M | $6M | $6M | $3M | |
| Accrued Liabilities | $5M | $9M | $8M | $6M | $6M | $7M | $7M | $6M | $5M | $6M | $6M | $7M | $6M | $6M | $5M | $4M | |
| Short-term Debt | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $7.0K | · | |
| Current Liabilities | $29M | $23M | $27M | $22M | $21M | $21M | $24M | $19M | $17M | $15M | $16M | $14M | $13M | $17M | $13M | $9M | |
| Capital Leases | $3M | $3M | $3M | $3M | $3M | $4M | $4M | $3M | $4M | $4M | $5M | $5M | $5M | $4M | $2M | $2M | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $192.0K | |
| Total Liabilities | $32M | $25M | $30M | $25M | $24M | $25M | $28M | $22M | $21M | $19M | $21M | $19M | $18M | $20M | $16M | $11M | |
| Long-term Debt | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $59.0K | · | |
| Total Debt | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $7.0K | · | |
| Common Stock | $10.0K | $10.0K | $10.0K | $10.0K | $10.0K | $9.0K | $9.0K | $9.0K | $9.0K | $9.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $5.0K | |
| Paid-in Capital | $1.10B | $1.09B | $1.07B | $1.05B | $1.04B | $849M | $837M | $827M | $816M | $809M | $505M | $501M | $497M | $493M | $489M | $356M | |
| Retained Earnings | $-653M | $-595M | $-546M | $-496M | $-455M | $-419M | $-379M | $-339M | $-305M | $-273M | $-215M | $-189M | $-167M | $-145M | $-125M | $-108M | |
| AOCI | $-500.0K | $-252.0K | $677.0K | $701.0K | $204.0K | $401.0K | $420.0K | $1M | $-1M | $-861.0K | $-424.0K | $-547.0K | $-251.0K | $-1M | $-2M | $-2M | |
| Stockholders' Equity | $448M | $493M | $522M | $559M | $589M | $430M | $459M | $489M | $510M | $535M | $290M | $311M | $329M | $347M | $361M | $246M | |
| Liabilities + Equity | $480M | $519M | $553M | $583M | $613M | $454M | $487M | $511M | $532M | $554M | $311M | $331M | $346M | $367M | $377M | $257M | |
| Shares Outstanding | 107,776,380 | 107,481,522 | 106,249,579 | 105,761,949 | 105,341,296 | 95,205,683 | 94,838,466 | 94,408,911 | 93,643,341 | 93,284,528 | 63,460,939 | 63,458,932 | 63,274,732 | 63,257,376 | 63,208,828 | 49,780,365 |
现金流 9
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $9M | $9M | $10M | $8M | $8M | $9M | $8M | $7M | $5M | $5M | $5M | $4M | $4M | $4M | $3M | $2M | |
| Operating Cash Flow | $-42M | $-43M | $-39M | $-35M | $-33M | $-38M | $-27M | $-27M | $-26M | $-29M | $-22M | $-20M | $-23M | $-12M | $-12M | $-16M | |
| CapEx | $32.0K | $260.0K | $73.0K | $89.0K | $50.0K | $44.0K | $274.0K | $520.0K | $221.0K | $297.0K | $457.0K | $759.0K | $4M | $3M | $1M | $554.0K | |
| Investing Cash Flow | $78M | $2M | $50M | $36M | $-162M | $44M | $21M | $25M | $37M | $-268M | $23M | $3M | $49M | $-76M | $-26M | $-46.0K | |
| Stock Issued | · | · | $0 | $0 | · | · | $0 | $0 | $0 | $239M | · | · | · | $-555.0K | · | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $239M | · | · | · | · | · | · | |
| Financing Cash Flow | $3M | $12M | $4M | $2M | $188M | $2M | $3M | $3M | $2M | $241M | $-211.0K | $369.0K | $21.0K | $-303.0K | $130M | $179.0K | |
| Net Change in Cash | $39M | $-28M | $15M | $3M | $-7M | $8M | $-3M | $1M | $13M | $-56M | $1M | $-16M | $26M | $-88M | $91M | $-16M | |
| Free Cash Flow | · | $-43M | · | · | · | · | · | · | · | $-29M | · | · | $-27M | · | · | · |
盈利能力 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -10.5% | -10.1% | · | -7.4% | -6.3% | -8.1% | · | -8.3% | -7.3% | -6.3% | -7.5% | -7.3% | -7.4% | · | -5.2% | -5.7% | |
| ROE | -11.1% | -10.6% | · | -7.8% | -6.6% | -8.5% | · | -8.8% | -7.7% | -6.6% | -7.9% | -7.7% | -7.8% | · | -5.4% | -5.9% |
流动性与偿付能力 3
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 16.2 | 22.6 | · | 26.5 | 28.9 | 21.0 | · | 26.3 | 30.2 | 37.1 | 18.2 | 22.0 | 26.2 | · | 27.8 | 27.5 | |
| Quick Ratio | 2.5 | 1.5 | · | 2.1 | 2.1 | 2.4 | · | 2.4 | 2.5 | 2.1 | 2.0 | 2.2 | 3.8 | · | 8.2 | 2.0 | |
| Debt / Equity | · | · | · | · | · | · | · | · | · | · | · | · | · | · | 0.0 | · |
估值 (TTM) 10
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-183M | $-167M | · | $-152M | $-143M | $-135M | · | $-120M | $-107M | $-99M | $-88M | $-78M | $-71M | · | $-61M | $-54M | |
| Market Cap | $4.38B | $3.39B | · | $1.72B | $1.38B | $2.09B | · | $2.52B | $1.69B | $1.70B | $364M | $492M | $422M | · | $622M | $396M | |
| Enterprise Value | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $512M | · | |
| P/E | -23.6 | -19.4 | · | -10.7 | -8.9 | -15.1 | · | -18.5 | -12.7 | -12.7 | -4.0 | -5.7 | -5.1 | · | -8.1 | -7.3 | |
| P/B | 9.8 | 6.9 | · | 3.1 | 2.3 | 4.9 | · | 5.2 | 3.3 | 3.2 | 1.3 | 1.6 | 1.3 | · | 1.7 | 1.6 | |
| P / Tangible Book | 9.8 | 6.9 | · | 3.1 | 2.3 | 4.9 | · | 5.2 | 3.3 | 3.2 | 1.3 | 1.6 | 1.3 | · | 1.7 | 1.6 | |
| P / Cash Flow | · | -79.6 | · | · | · | -55.3 | · | · | · | -59.5 | · | · | -18.5 | · | · | · | |
| P / FCF | · | -79.1 | · | · | · | · | · | · | · | -58.9 | · | · | -15.5 | · | · | · | |
| EV / EBITDA | · | · | · | · | · | · | · | · | · | · | · | · | · | · | -28.0 | · | |
| Earnings Yield | -4.2% | -5.1% | · | -9.4% | -11.2% | -6.6% | · | -5.4% | -7.9% | -7.9% | -25.3% | -17.5% | -19.8% | · | -12.4% | -13.7% |
财务报表 损益表、资产负债表、现金流量表 — 年度，近5年
损益表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 净收入 | $-168M | $-134M | $-100M | $-68M | $-43M |
| 稀释后每股收益 (EPS) | $-1.63 | $-1.45 | $-1.57 | $-1.26 | $-1.14 |
资产负债表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 流动比率 | 19.9 | 19.9 | 19.5 | 21.5 | 27.0 |
| 速动比率 | 2.2 | 1.7 | 5.1 | 1.3 | 1.5 |
现金流
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 自由现金流 | $-144M | $-110M | $-98M | $-58M | $-34M |
我的指标 您的个人关注列表 — 来自完整基本面的选定行
📊
选择对您重要的指标 — 点击上方完整基本面中任意行的 ➕。
您的选择已保存，并会跟随您浏览所有股票。
机构持有人 (13F) 249 家申报者 · $4.0B 总计 · 截至 2026年6月30日
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
机构活动 — Q2 2026 与上一季度对比
| 新仓位 | 已退出持仓 | 增加 | 减少 | 净股数变动 |
|---|---|---|---|---|
| 47 (+1 与上一季度对比) | 24 (+1 与上一季度对比) | 79 (+12 与上一季度对比) | 74 (+9 与上一季度对比) | +3.3M |
与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天，外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过，优先显示最近一个已完整报告的季度对。
| 机构 | 价值 | 股份 | % 已追踪的13F | 类型 |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | $630516330 | 15518492 | 15.63% | 股份 |
| Paradigm Biocapital Advisors LP | $415053937 | 10215455 | 10.29% | 股份 |
| RA CAPITAL MANAGEMENT, L.P. | $340996620 | 8392730 | 8.46% | 股份 |
| NOVO HOLDINGS A/S | $217370500 | 5350000 | 5.39% | 股份 |
| Driehaus Capital Management LLC | $192123952 | 4728623 | 4.76% | 股份 |
| PERCEPTIVE ADVISORS LLC | $177714564 | 4373974 | 4.41% | 股份 |
| VANGUARD CAPITAL MANAGEMENT LLC | $156859022 | 3860670 | 3.89% | 股份 |
| BAKER BROS. ADVISORS LP | $150400843 | 3701719 | 3.73% | 股份 |
| Siren, L.L.C. | $129391476 | 3184629 | 3.21% | 股份 |
| FMR LLC | $107911899 | 2655966 | 2.68% | 股份 |
| Cormorant Asset Management, LP | $101981300 | 2510000 | 2.53% | 股份 |
| Integral Health Asset Management, LLC | $81260000 | 2000000 | 2.01% | 股份 |
| BRAIDWELL LP | $81136688 | 1996965 | 2.01% | 股份 |
| GEODE CAPITAL MANAGEMENT, LLC | $77257283 | 1901081 | 1.92% | 股份 |
| STATE STREET CORP | $74268674 | 1827927 | 1.84% | 股份 |
| ALLIANCEBERNSTEIN L.P. | $66749256 | 2119024 | 1.66% | 股份 |
| MPM BIOIMPACT LLC | $65852291 | 1620780 | 1.63% | 股份 |
| MORGAN STANLEY | $65647597 | 1615742 | 1.63% | 股份 |
| BANK OF AMERICA CORP /DE/ | $56886145 | 1400102 | 1.41% | 股份 |
| Qube Research & Technologies Ltd | $50889359 | 1252507 | 1.26% | 股份 |
| AMERICAN CENTURY COMPANIES INC | $45793233 | 1127078 | 1.14% | 股份 |
| First Light Asset Management, LLC | $44496798 | 1095171 | 1.10% | 股份 |
| DIMENSIONAL FUND ADVISORS LP | $43383658 | 1067774 | 1.08% | 股份 |
| VICTORY CAPITAL MANAGEMENT INC | $36683608 | 902870 | 0.91% | 股份 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $31953707 | 786456 | 0.79% | 股份 |
| Aberdeen Group plc | $26325233 | 647926 | 0.65% | 股份 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $25212215 | 620532 | 0.63% | 股份 |
| Tyro Capital Management LLC | $24904768 | 612965 | 0.62% | 股份 |
| Parkman Healthcare Partners LLC | $23444973 | 577036 | 0.58% | 股份 |
| Artisan Partners Limited Partnership | $23359203 | 574925 | 0.58% | 股份 |
| VANGUARD FIDUCIARY TRUST CO | $22276820 | 548285 | 0.55% | 股份 |
| NORGES BANK | $20726988 | 510140 | 0.51% | 股份 |
| Opaleye Management Inc. | $20315000 | 500000 | 0.50% | 股份 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $18771060 | 462000 | 0.47% | 股份 |
| Soleus Capital Management, L.P. | $18319620 | 450889 | 0.45% | 股份 |
| New Leaf Venture Partners, L.L.C. | $16709211 | 1030161 | 0.41% | 股份 |
| GOLDMAN SACHS GROUP INC | $15838224 | 389816 | 0.39% | 股份 |
| Sofinnova Investments, Inc. | $15476901 | 380923 | 0.38% | 股份 |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $13570989 | 334014 | 0.34% | 股份 |
| CITADEL ADVISORS LLC | $13539054 | 333228 | 0.34% | 股份 |
| Squadron Capital Management LLC | $11782700 | 290000 | 0.29% | 股份 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $11511820 | 283333 | 0.29% | 股份 |
| DIADEMA PARTNERS LP | $11060055 | 272214 | 0.27% | 股份 |
| KENNEDY CAPITAL MANAGEMENT LLC | $10425983 | 256608 | 0.26% | 股份 |
| Schonfeld Strategic Advisors LLC | $10368855 | 255202 | 0.26% | 股份 |
| DAFNA Capital Management LLC | $9215656 | 226819 | 0.23% | 股份 |
| Woodline Partners LP | $9112903 | 224290 | 0.23% | 股份 |
| PRUDENTIAL FINANCIAL INC | $9053380 | 222825 | 0.22% | 股份 |
| PEREGRINE CAPITAL MANAGEMENT LLC | $8067899 | 198570 | 0.20% | 股份 |
| SEB Asset Management AB | $7884765 | 194063 | 0.20% | 股份 |
| Granahan Investment Management, LLC | $7873200 | 193778 | 0.20% | 股份 |
| BARCLAYS PLC | $7694956 | 189391 | 0.19% | 股份 |
| D. E. Shaw & Co., Inc. | $6616027 | 162836 | 0.16% | 股份 |
| Caption Management, LLC | $6480485 | 159500 | 0.16% | 买入期权 |
| ADAR1 Capital Management, LLC | $5818175 | 143199 | 0.14% | 股份 |
| KVP Capital Advisors, LP | $5403790 | 133000 | 0.13% | 股份 |
| NEUBERGER BERMAN GROUP LLC | $5201900 | 128031 | 0.13% | 股份 |
| Point72 Asset Management, L.P. | $4764355 | 117262 | 0.12% | 股份 |
| Quantum Private Wealth, LLC | $4606640 | 113380 | 0.11% | 股份 |
| ALPS ADVISORS INC | $4420341 | 108795 | 0.11% | 股份 |
| Moody Aldrich Partners LLC | $4264200 | 104952 | 0.11% | 股份 |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | $4063000 | 100000 | 0.10% | 卖出期权 |
| Artia Global Partners LP | $4014244 | 98800 | 0.10% | 股份 |
| Nuveen, LLC | $3934203 | 96830 | 0.10% | 股份 |
| Swiss National Bank | $3932984 | 96800 | 0.10% | 股份 |
| HighVista Strategies LLC | $3697168 | 90996 | 0.09% | 股份 |
| BlackRock, Inc. | $3668036 | 90279 | 0.09% | 股份 |
| RHUMBLINE ADVISERS | $3666114 | 90232 | 0.09% | 股份 |
| JANUS HENDERSON GROUP PLC | $3597171 | 114215 | 0.09% | 股份 |
| Ally Bridge Group (NY) LLC | $3384479 | 83300 | 0.08% | 股份 |
| BOOTHBAY FUND MANAGEMENT, LLC | $3361482 | 82734 | 0.08% | 股份 |
| NEW YORK STATE COMMON RETIREMENT FUND | $3258404 | 80197 | 0.08% | 股份 |
| Centiva Capital, LP | $3047250 | 75000 | 0.08% | 买入期权 |
| Jefferies Financial Group Inc. | $2900535 | 71389 | 0.07% | 股份 |
| Persistent Asset Partners Ltd | $2821388 | 69441 | 0.07% | 股份 |
| Bank of New York Mellon Corp | $2805298 | 69045 | 0.07% | 股份 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $2638000 | 64918 | 0.07% | 股份 |
| TUDOR INVESTMENT CORP ET AL | $2313228 | 56934 | 0.06% | 股份 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2312699 | 73419 | 0.06% | 股份 |
| STATE OF WISCONSIN INVESTMENT BOARD | $2312253 | 56910 | 0.06% | 股份 |
| CITADEL ADVISORS LLC | $2263091 | 55700 | 0.06% | 买入期权 |
| CITIGROUP INC | $2252324 | 55435 | 0.06% | 股份 |
| HighMark Wealth Management LLC | $2160662 | 53179 | 0.05% | 股份 |
| TWO SIGMA INVESTMENTS, LP | $2013135 | 49548 | 0.05% | 股份 |
| ALGERT GLOBAL LLC | $1919361 | 47240 | 0.05% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1913673 | 47100 | 0.05% | 卖出期权 |
| XTX Topco Ltd | $1862154 | 45832 | 0.05% | 股份 |
| BNP PARIBAS FINANCIAL MARKETS | $1770940 | 43587 | 0.04% | 股份 |
| MetLife Investment Management, LLC | $1698497 | 41804 | 0.04% | 股份 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1655957 | 40757 | 0.04% | 股份 |
| Ensign Peak Advisors, Inc | $1640599 | 40379 | 0.04% | 股份 |
| Knights of Columbus Asset Advisors LLC | $1569984 | 38641 | 0.04% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1568318 | 38600 | 0.04% | 买入期权 |
| Aquatic Capital Management LLC | $1499978 | 36918 | 0.04% | 股份 |
| VANGUARD ASSET MANAGEMENT, Ltd | $1452279 | 35744 | 0.04% | 股份 |
| Vanguard Global Advisers, LLC | $1434361 | 35303 | 0.04% | 股份 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1338312 | 32939 | 0.03% | 股份 |
| JANE STREET GROUP, LLC | $1178676 | 29010 | 0.03% | 股份 |
| Invesco Ltd. | $1158077 | 28503 | 0.03% | 股份 |
| Verdad Advisers, LP | $1106517 | 27234 | 0.03% | 股份 |
公司内部人士 15 位内幕人士 · 0 位高管 · 7 位董事
| 内部人士 | 角色 | 上次活动 | 持股数量 | 买入 12个月 | 卖出 12个月 | 净额 12个月 |
|---|---|---|---|---|---|---|
| Jonathan C Fox | 董事 | 2026年7月1日 A | 24833 | 0 | 0 | $0 |
| Christopher Nathan Martin | 董事 | 2026年6月5日 A | — | 0 | 0 | $0 |
| Badreddin Edris | 董事 | 2026年6月5日 A | — | 0 | 0 | $0 |
| Laura Brege | 董事 | 2026年6月5日 A | — | 0 | 0 | $0 |
| Arlene Morris | 董事 | 2026年6月5日 A | — | 0 | 0 | $0 |
| Peter A. Thompson | 董事 | 2026年6月5日 A | 443792 | 0 | 0 | $0 |
| Jonathan D Root | 董事 | 2026年6月5日 A | 0 | 0 | 0 | $0 |
| Novo Holdings A/S | 10% 所有者 | 2022年9月14日 P | 6071703 | 0 | 0 | $0 |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | 10% 所有者 | 2021年3月30日 C | 681812 | 0 | 0 | $0 |
| Alan J Russell | — | 2026年8月12日 A | 31466 | 0 | 5 | $-8140060 |
| Behrad Derakhshan | — | 2026年8月12日 A | 31826 | 0 | 4 | $-223420 |
| Michael Nofi | — | 2026年8月12日 A | — | 0 | 0 | $0 |
| Joanne M. Donovan | — | 2026年8月12日 A | 8625 | 0 | 5 | $-412712 |
| John R Moore | — | 2026年8月12日 A | 17697 | 0 | 4 | $-219831 |
| Kevin Koch | — | 2026年8月12日 A | 52488 | 0 | 3 | $-785049 |
来自SEC表格3/4/5申报的内部人士；净额=仅公开市场买卖
激进投资者及 5%+ 股东 3 持仓
提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权，意图影响发行人（激进股东持股、董事会活动、并购）。每一行显示该申报人持仓的最新已知状态。
| 申报人 | 已申报 | 持股 | 状态 | 目的 | 申报 |
|---|---|---|---|---|---|
| Novo Holdings A/S ×7 申报 | 2026年4月27日 | 4.90% | 修订 | — | SEC |
| ORBIMED ADVISORS LLC, ORBIMED CAPITAL GP VI LLC, OrbiMed Genesis GP LLC, ORBIMED CAPITAL LLC ×5 申报 | 2025年5月12日 | 14.50% | 修订 | — | SEC |
| U.S. Venture Partners XI, L.P. (“USVP XI”), Presidio Management Group XI, L.L.C. (“PMG XI”), Casey M. Tansey, Jonathan D. Root ×2 申报 | 2023年2月1日 | — | 初始申报 | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF持仓 由 45 只交易所交易基金持有
权重仅反映直接股权持仓（N-PORT）；杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。
| 基金 | 权重 | 单位 | 截至 | 来源 |
|---|---|---|---|---|
| IBRN · iShares Trust | 3.54% | 6153 SH | 2026年8月8日 | 每日 |
| SBIO · ALPS ETF Trust | 2.33% | 110576 NS | 2026年5月31日 | N-PORT |
| PILL · Direxion Shares ETF Trust | 1.34% | 5567 NS | 2026年4月30日 | N-PORT |
| BBC · ETFis Series Trust I | 0.97% | 11685 NS | 2026年4月30日 | N-PORT |
| IHE · iShares Trust | 0.74% | 269166 SH | 2026年8月8日 | 每日 |
| MMSC · First Trust Exchange-Traded Fund ... | 0.63% | 9620 NS | 2026年5月31日 | N-PORT |
| DWAS · Invesco Exchange-Traded Fund Trus... | 0.47% | 48340 SH | 2026年8月8日 | 每日 |
| IBBQ · Invesco Exchange-Traded Fund Trus... | 0.32% | 5857 SH | 2026年8月8日 | 每日 |
| IBB · iShares Trust | 0.27% | 577144 SH | 2026年8月8日 | 每日 |
| IWO · iShares Trust | 0.20% | 647964 SH | 2026年8月8日 | 每日 |
| BIB · ProShares Trust | 0.18% | 3966 NS | 2026年5月31日 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.17% | 76681 SH | 2026年8月8日 | 每日 |
| VFMO · VANGUARD WELLINGTON FUND | 0.13% | 65171 SH | 2026年8月8日 | 每日 |
| BBSC · J.P. Morgan Exchange-Traded Fund ... | 0.13% | 30264 NS | 2026年4月30日 | N-PORT |
| IWM · iShares Trust | 0.10% | 1809565 SH | 2026年8月8日 | 每日 |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.09% | 411642 SH | 2026年8月8日 | 每日 |
| ESML · iShares Trust | 0.06% | 42227 SH | 2026年8月8日 | 每日 |
| RSSL · Global X Funds | 0.06% | 29238 NS | 2026年4月30日 | N-PORT |
| ISCG · iShares Trust | 0.06% | 13816 SH | 2026年8月8日 | 每日 |
| ISCB · iShares Trust | 0.06% | 3892 SH | 2026年8月8日 | 每日 |
| ISCV · iShares Trust | 0.06% | 9273 SH | 2026年8月8日 | 每日 |
| ITWO · ProShares Trust | 0.06% | 3175 NS | 2026年5月31日 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0.05% | 355389 NS | 2026年5月31日 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.05% | 30883 SH | 2026年8月8日 | 每日 |
| DFAS · Dimensional ETF Trust | 0.04% | 167330 NS | 2026年4月30日 | N-PORT |
| UWM · ProShares Trust | 0.03% | 2484 NS | 2026年5月31日 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.03% | 864416 SH | 2026年8月8日 | 每日 |
| VHT · VANGUARD WORLD FUND | 0.03% | 145298 SH | 2026年8月8日 | 每日 |
| FHLC · FIDELITY COVINGTON TRUST | 0.03% | 24144 NS | 2026年4月30日 | N-PORT |
| URTY · ProShares Trust | 0.02% | 2510 NS | 2026年5月31日 | N-PORT |
| WSML · iShares Trust | 0.02% | 3101 SH | 2026年8月8日 | 每日 |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0.01% | 2733 NS | 2026年5月31日 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0.01% | 33343 NS | 2026年5月31日 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0.01% | 2902915 SH | 2026年8月8日 | 每日 |
| HDG · ProShares Trust | 0.01% | 63 NS | 2026年5月31日 | N-PORT |
| TILT · FlexShares Trust | 0.01% | 5888 NS | 2026年4月30日 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0.01% | 7155 NS | 2026年5月31日 | N-PORT |
| DFAC · Dimensional ETF Trust | 0.01% | 105864 NS | 2026年4月30日 | N-PORT |
| DCOR · Dimensional ETF Trust | 0.01% | 6245 NS | 2026年4月30日 | N-PORT |
| ITOT · iShares Trust | 0.00% | 105818 SH | 2026年8月8日 | 每日 |
| IWV · iShares Trust | 0.00% | 20898 SH | 2026年8月8日 | 每日 |
| DFAU · Dimensional ETF Trust | 0.00% | 15310 NS | 2026年4月30日 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0.00% | 44236 NS | 2026年5月31日 | N-PORT |
| DFUS · Dimensional ETF Trust | 0.00% | 9382 NS | 2026年4月30日 | N-PORT |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 5890 SH | 2026年8月8日 | 每日 |