AMLX Amylyx Pharmaceuticals, Inc. - Common Stock
$37.58
价格 · 八月 19, 2026
截至...的财报数据 八月 6, 2026
AMLX 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围
价格
$37.58
市值
$4.17B
P/E (TTM)
-24.8
每股收益 (TTM)
$-1.53
营收 (TTM)
$0
股息收益率
—
ROE
-61.2%
负债/权益
—
52周区间
$8 – $38
AMLX 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图
Configure
10年表现 收入、净利润、利润率和每股收益趋势
营收与净利润
$0
2021-12-31
→
2025-12-31
EPS
$-1.53
2021-12-31
→
2025-12-31
自由现金流
$-123M
2022-12-31
→
2025-12-31
利润率
—
估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜？
指标
5年趋势
AMLX
同行中位数
P/E (TTM)
-24.8
29.4
P/B (市净率)
13.7
6.5
Price / FCF (股价/自由现金流)
-33.8
—
盈利能力 毛利率、营业利润率和净利率；股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)
指标
5年趋势
AMLX
同行中位数
ROA
-55.0%
-8.2%
ROE
-61.2%
-19.4%
ROIC
-50.2%
—
财务健康 债务、流动性、偿付能力 — 资产负债表强度
指标
5年趋势
AMLX
同行中位数
Current Ratio (流动比率)
14.3
3.6
Quick Ratio (速动比率)
14.0
—
成长 营收、每股收益 (EPS) 和净利润增长：同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)
指标
5年趋势
AMLX
同行中位数
Revenue YoY (营收同比增长)
-77.1%
—
Revenue CAGR 3Y (营收3年复合年增长率)
574.3%
—
资本效率 资产周转率、库存周转率、应收账款周转率
指标
5年趋势
AMLX
同行中位数
AMLX 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间
买入
17 位分析师
- 强烈买入 8 47.1%
- 买入 7 41.2%
- 持有 2 11.8%
- 卖出 0 0.0%
- 强烈卖出 0 0.0%
12个月价格目标
11 位分析师 · 2026-08-19
中位数
$28.00
现在
$37.58
最低
$20.00
最高
$40.00
中位数目标
$28.00
-25.5%
平均目标
$28.09
-25.3%
收益历史 每股收益实际值 vs 预估值，惊喜%，达标率，下次财报日期
平均惊喜
0.03%
| 期间 | EPS Actual | EPS 预期 | 惊喜 |
|---|---|---|---|
| 2026年6月30日 | $-0.39 | $-0.37 | -0.02% |
| 2026年3月31日 | $-0.37 | $-0.34 | -0.03% |
| 2025年12月31日 | $-0.30 | $-0.37 | 0.07% |
| 2025年9月30日 | $-0.37 | $-0.46 | 0.09% |
| 2025年6月30日 | $-0.46 | $-0.45 | -0.01% |
| 2025年3月31日 | $-0.42 | $-0.48 | 0.06% |
同行比较（GICS 子行业） 关键指标与行业同行对比
| 股票代码 | 市值 | P/E | 营收同比增长 | 净利润率 | ROE | 毛利率 |
|---|---|---|---|---|---|---|
| AMLX | $1.33B | -7.9 | -77.1% | — | -61.2% | — |
| GPCR | $14.78B | -86.9 | — | — | -12.3% | — |
| OGN | $1.87B | 10.0 | -2.9% | 3.0% | 25.2% | 53.3% |
| MBX | $1.42B | -13.3 | — | — | -29.6% | — |
| ALMS | — | -3.4 | — | -1011.8% | -61.9% | — |
| TARS | $3.48B | -51.5 | 146.7% | -14.7% | -19.7% | — |
| SUPN | $2.86B | -73.1 | 8.6% | -5.4% | -3.6% | — |
| ATAI | $223M | -1.4 | -1.9% | -48464.0% | -83.1% | — |
| TRVI | $1.61B | -39.1 | — | — | -22.4% | — |
| NKTR | $862M | -4.3 | -43.9% | -297.1% | -500.1% | — |
完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表
损益表 16
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue | $0 | $87M | $381M | $22M | $285.0K | |
| Cost of Revenue | $0 | $6M | $25M | $3M | · | |
| R&D Expense | $90M | $104M | $128M | $93M | $44M | |
| SG&A Expense | $63M | $114M | $188M | $127M | $39M | |
| Operating Expenses | $153M | $402M | $342M | $224M | $83M | |
| Operating Income | $-153M | $-315M | $39M | $-201M | $-83M | |
| Interest Income | $9M | $14M | $16M | $4M | $36.0K | |
| Other Non-op | $-700.0K | $-1M | $-660.0K | $-551.0K | $-51.0K | |
| Pretax Income | $-145M | $-302M | $54M | $-198M | $-88M | |
| Income Tax | $46.0K | $-393.0K | $5M | $774.0K | · | |
| Net Income | $-145M | $-302M | $49M | $-198M | $-88M | |
| EPS (Basic) | $-1.53 | $-4.43 | $0.73 | $-3.39 | $-13.35 | |
| EPS (Diluted) | $-1.53 | $-4.43 | $0.70 | $-3.39 | $-13.35 | |
| Shares (Basic) | 94,565,567 | 68,142,158 | 67,234,465 | 58,495,587 | 6,586,349 | |
| Shares (Diluted) | 94,565,567 | 68,142,158 | 69,991,340 | 58,495,587 | 6,586,349 | |
| EBITDA | $-153M | $-315M | $39M | $-201M | · |
资产负债表 22
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Cash & Equivalents | $227M | $77M | $170M | $63M | $50M | |
| Short-term Investments | $90M | $99M | $201M | $284M | $46M | |
| Receivables | $88.0K | $447.0K | $40M | $15M | · | |
| Inventory | · | · | $38M | $10M | · | |
| Prepaid Expense | $7M | $12M | $15M | $10M | $5M | |
| Current Assets | $324M | $189M | $465M | $382M | $105M | |
| PP&E (Net) | $310.0K | $961.0K | $3M | $3M | $474.0K | |
| PP&E (Gross) | $2M | $2M | $4M | $3M | $527.0K | |
| Accum. Depreciation | $2M | $1M | $2M | $540.0K | $53.0K | |
| Other Non-current Assets | $2M | $24.0K | $701.0K | $466.0K | · | |
| Total Assets | $333M | $194M | $517M | $391M | $106M | |
| Accounts Payable | $4M | $3M | $22M | $6M | $4M | |
| Accrued Liabilities | $18M | $24M | $58M | $38M | · | |
| Current Liabilities | $23M | $28M | $82M | $47M | $17M | |
| Capital Leases | $5M | $463.0K | $2M | $4M | · | |
| Total Liabilities | $27M | $29M | $84M | $51M | $17M | |
| Common Stock | $11.0K | $7.0K | $7.0K | $7.0K | $1.0K | |
| Retained Earnings | $-751M | $-607M | $-305M | $-354M | $-156M | |
| AOCI | $404.0K | $-92.0K | $197.0K | $-86.0K | $9.0K | |
| Stockholders' Equity | $305M | $165M | $433M | $341M | $-151M | |
| Liabilities + Equity | $333M | $194M | $517M | $391M | $106M | |
| Shares Outstanding | 109,884,502 | 68,629,738 | 67,707,432 | 66,512,011 | 7,020,487 |
现金流 9
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Stock-based Comp | $28M | $33M | $37M | $22M | $3M | |
| Restructuring | $0 | $23M | · | · | · | |
| Operating Cash Flow | $-123M | $-168M | $12M | $-180M | $-75M | |
| CapEx | $138.0K | $157.0K | $1M | $3M | $353.0K | |
| Investing Cash Flow | $14M | $76M | $92M | $-239M | $-46M | |
| Financing Cash Flow | $257M | $348.0K | $4M | $432M | $159M | |
| Net Change in Cash | $149M | $-92M | $108M | $13M | $37M | |
| Taxes Paid | $-1M | $235.0K | · | · | · | |
| Free Cash Flow | $-123M | $-168M | $11M | $-182M | · |
盈利能力 7
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Operating Margin | · | -360.2% | 10.2% | -905.7% | · | |
| Net Margin | · | -345.4% | 12.9% | -892.4% | · | |
| Pretax Margin | · | -345.8% | 14.3% | -888.9% | · | |
| EBITDA Margin | · | -360.2% | 10.2% | -905.7% | · | |
| ROA | -55.0% | -84.9% | 10.8% | -79.8% | · | |
| ROE | -61.2% | -167.2% | 11.6% | -81.9% | · | |
| ROIC | -50.2% | -190.8% | 8.1% | -59.3% | · |
流动性与偿付能力 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Current Ratio | 14.3 | 6.7 | 5.7 | 8.2 | · | |
| Quick Ratio | 14.0 | 6.2 | 5.0 | 7.8 | · |
效率 3
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.2 | 0.8 | 0.1 | · | |
| Inventory Turnover | · | · | 1.1 | 0.6 | · | |
| Receivables Turnover | 0.0 | 4.3 | 13.8 | 2.9 | · |
增长率 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue YoY | · | -77.1% | 1612.9% | 7700.0% | · | |
| Revenue CAGR 3Y | · | 574.3% | · | · | · |
估值 (TTM) 10
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $87M | $381M | $22M | $285.0K | |
| Net Income TTM | $-145M | $-302M | $49M | $-198M | $-88M | |
| Market Cap | $1.33B | $259M | $997M | $2.46B | · | |
| P/E | -7.9 | -0.9 | 21.0 | -10.9 | · | |
| P/S | · | 3.0 | 2.6 | 110.6 | · | |
| P/B | 4.3 | 1.6 | 2.3 | 7.2 | · | |
| P / Tangible Book | 4.3 | 1.6 | 2.3 | 7.2 | · | |
| P / Cash Flow | -10.8 | -1.5 | 83.6 | -13.7 | · | |
| P / FCF | -10.7 | -1.5 | 93.3 | -13.5 | · | |
| Earnings Yield | -12.7% | -117.2% | 4.8% | -9.2% | · |
损益表 16
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | $0 | $0 | $0 | $0 | $-665.0K | $416.0K | $-1M | $89M | $108M | $103M | $98M | $71M | $22M | $345.0K | |
| Cost of Revenue | · | · | $0 | $0 | $0 | $0 | $0 | $0 | $8.0K | $6M | $9M | $5M | $6M | $5M | $3M | $172.0K | |
| R&D Expense | $24M | $28M | $21M | $20M | $27M | $22M | $23M | $21M | $23M | $37M | $45M | $30M | $29M | $24M | $23M | $25M | |
| SG&A Expense | $22M | $16M | $15M | $16M | $16M | $16M | $17M | $18M | $22M | $58M | $52M | $49M | $43M | $44M | $41M | $30M | |
| Operating Expenses | $46M | $44M | $37M | $36M | $43M | $38M | $40M | $76M | $75M | $211M | $107M | $84M | $78M | $73M | $66M | $55M | |
| Operating Income | $-46M | $-44M | $-37M | $-36M | $-43M | $-38M | $-41M | $-76M | $-76M | $-122M | $2M | $19M | $20M | $-2M | $-45M | $-55M | |
| Interest Income | $2M | $3M | $3M | $2M | $2M | $2M | $2M | $3M | $4M | $4M | $4M | $4M | $4M | $4M | $3M | $601.0K | |
| Other Non-op | $-53.0K | $-75.0K | $361.0K | $-180.0K | $-546.0K | $-335.0K | $157.0K | $-141.0K | $-483.0K | $-747.0K | $171.0K | $-488.0K | $-81.0K | $-262.0K | $-689.0K | $199.0K | |
| Pretax Income | · | · | $-33M | $-34M | $-41M | $-36M | $-38M | $-73M | $-73M | $-119M | $6M | $22M | $24M | $1M | $-42M | $-54M | |
| Income Tax | · | · | $46.0K | $0 | $0 | $0 | $-635.0K | $0 | $0 | $242.0K | $2M | $2M | $2M | $-170.0K | $579.0K | $-125.0K | |
| Net Income | $-43M | $-41M | $-33M | $-34M | $-41M | $-36M | $-38M | $-73M | $-73M | $-119M | $5M | $21M | $22M | $2M | $-43M | $-54M | |
| EPS (Basic) | $-0.39 | $-0.37 | $-0.28 | $-0.37 | $-0.46 | $-0.42 | $-0.54 | $-1.07 | $-1.07 | $-1.75 | $0.07 | $0.31 | $0.33 | $0.02 | $-0.61 | $-0.92 | |
| EPS (Diluted) | $-0.39 | $-0.37 | $-0.28 | $-0.37 | $-0.46 | $-0.42 | $-0.54 | $-1.07 | $-1.07 | $-1.75 | $0.07 | $0.30 | $0.31 | $0.02 | $-0.61 | $-0.92 | |
| Shares (Basic) | 111,196,883 | 110,563,360 | -173,603,039 | 93,332,930 | 89,138,568 | 85,697,108 | -135,828,573 | 68,091,446 | 68,024,929 | 67,854,356 | -134,131,092 | 67,414,669 | 67,233,617 | 66,717,271 | -109,917,852 | 58,533,226 | |
| Shares (Diluted) | 111,196,883 | 110,563,360 | -173,603,039 | 93,332,930 | 89,138,568 | 85,697,108 | -135,828,573 | 68,091,446 | 68,024,929 | 67,854,356 | -140,752,912 | 69,748,547 | 70,132,040 | 70,863,665 | -109,917,852 | 58,533,226 | |
| EBITDA | $-46M | $-44M | · | $-36M | $-43M | $-38M | · | $-76M | $-76M | $-122M | · | $19M | $20M | $-2M | · | $-55M |
资产负债表 22
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $49M | $229M | $227M | $225M | $58M | $60M | $77M | $72M | $75M | $171M | $170M | $135M | $248M | $115M | $63M | $108M | |
| Short-term Investments | $201M | $51M | $90M | $119M | $123M | $144M | $99M | $163M | $235M | $203M | $201M | $220M | $110M | $231M | $284M | $55M | |
| Receivables | · | · | $88.0K | $132.0K | $103.0K | $300.0K | $447.0K | $2M | $4M | $20M | $40M | $29M | $33M | $18M | $15M | $137.0K | |
| Inventory | · | · | · | · | · | · | · | · | · | · | $38M | $32M | $25M | $13M | $10M | $563.0K | |
| Prepaid Expense | $6M | $5M | $7M | $9M | $6M | $12M | $12M | $9M | $13M | $17M | $15M | $17M | $12M | $13M | $10M | $8M | |
| Current Assets | $256M | $285M | $324M | $353M | $187M | $216M | $189M | $245M | $327M | $411M | $465M | $434M | $427M | $389M | $382M | $172M | |
| PP&E (Net) | $199.0K | $212.0K | $310.0K | $399.0K | $445.0K | $816.0K | $961.0K | $1M | $1M | $2M | $3M | $3M | $3M | $3M | $3M | $2M | |
| PP&E (Gross) | · | · | $2M | · | · | · | $2M | · | · | · | $4M | · | · | · | $3M | · | |
| Accum. Depreciation | · | · | $2M | · | · | · | $1M | · | · | · | $2M | · | · | · | $540.0K | · | |
| Other Non-current Assets | · | $2M | · | $2M | · | $11.0K | · | $482.0K | $479.0K | $493.0K | $701.0K | $476.0K | $466.0K | $466.0K | $466.0K | $456.0K | |
| Total Assets | $265M | $294M | $333M | $363M | $195M | $220M | $194M | $251M | $332M | $417M | $517M | $467M | $454M | $408M | $391M | $181M | |
| Accounts Payable | $6M | $4M | $4M | $5M | $3M | $5M | $3M | $1M | $5M | $21M | $22M | $6M | $25M | $11M | $6M | $7M | |
| Accrued Liabilities | $15M | $11M | $18M | $19M | $17M | $12M | $24M | $50M | $63M | $68M | $58M | $37M | $37M | $39M | $38M | · | |
| Current Liabilities | $21M | $16M | $23M | $26M | $21M | $18M | $28M | $54M | $70M | $92M | $82M | $46M | $64M | $52M | $47M | $33M | |
| Capital Leases | $4M | $4M | $5M | $5M | $5M | $327.0K | $463.0K | $595.0K | $772.0K | $1M | $2M | $3M | $3M | $4M | $4M | $5M | |
| Total Liabilities | $25M | $20M | $27M | $31M | $27M | $18M | $29M | $55M | $71M | $93M | $84M | $48M | $67M | $55M | $51M | $37M | |
| Common Stock | $11.0K | $11.0K | $11.0K | $11.0K | $9.0K | $9.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $6.0K | |
| Retained Earnings | $-836M | $-793M | $-751M | $-718M | $-684M | $-643M | $-607M | $-569M | $-496M | $-424M | $-305M | $-310M | $-331M | $-353M | $-354M | $-312M | |
| AOCI | $19.0K | $240.0K | $404.0K | $815.0K | $551.0K | $0 | $-92.0K | $641.0K | $-97.0K | $-77.0K | $197.0K | $-151.0K | $-72.0K | $25.0K | $-86.0K | $-725.0K | |
| Stockholders' Equity | $239M | $273M | $305M | $332M | $168M | $201M | $165M | $196M | $261M | $324M | $433M | $418M | $386M | $353M | $341M | $144M | |
| Liabilities + Equity | $265M | $294M | $333M | $363M | $195M | $220M | $194M | $251M | $332M | $417M | $517M | $467M | $454M | $408M | $391M | $181M | |
| Shares Outstanding | 111,368,283 | 111,026,477 | 109,884,502 | 109,766,382 | 89,156,350 | 89,080,821 | 68,629,738 | 68,545,508 | 68,079,057 | 67,975,587 | 67,707,432 | 67,505,126 | 67,354,417 | 67,095,603 | 66,512,011 | 58,533,226 |
现金流 9
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $8M | $6M | $6M | $7M | $7M | $7M | $7M | $7M | $10M | $10M | $10M | $10M | $10M | $8M | $6M | $6M | |
| Restructuring | · | · | $0 | $0 | $0 | · | $0 | $0 | $23M | · | · | · | · | · | · | · | |
| Operating Cash Flow | $-31M | $-37M | $-28M | $-30M | $-25M | $-40M | $-59M | $-42M | $-67M | $-489.0K | $14M | $-5M | $9M | $-5M | $-50M | $-43M | |
| CapEx | · | · | $86.0K | $24.0K | $17.0K | $11.0K | $20.0K | $-19.0K | $89.0K | $67.0K | $356.0K | $357.0K | $278.0K | $250.0K | $620.0K | $459.0K | |
| Investing Cash Flow | $-150M | $36M | $29M | $5M | $23M | $-44M | $65M | $39M | $-29M | $819.0K | $21M | $-108M | $123M | $56M | $-228M | $84M | |
| Financing Cash Flow | $1M | $3M | $-208.0K | $192M | $-31.0K | $66M | $110.0K | $80.0K | $27.0K | $131.0K | $230.0K | $889.0K | $1M | $1M | $232M | $0 | |
| Net Change in Cash | $-180M | $2M | $1M | $167M | $-2M | $-18M | $6M | $-2M | $-96M | $351.0K | $35M | $-113M | $133M | $52M | $-45M | $41M | |
| Taxes Paid | · | · | · | · | $-30.0K | $-30.0K | $499.0K | $17.0K | $-6.0K | $-275.0K | · | $-2M | · | · | · | · | |
| Free Cash Flow | · | · | · | · | · | $-40M | · | · | · | $-556.0K | · | · | · | $-5M | · | · |
盈利能力 7
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | -18187.7% | 7457.1% | -137.8% | · | 18.2% | 20.6% | -2.9% | · | -15849.6% | |
| Net Margin | · | · | · | · | · | · | · | -17476.9% | 7106.6% | -134.0% | · | 20.3% | 22.5% | 2.2% | · | -15581.5% | |
| Pretax Margin | · | · | · | · | · | · | · | -17476.9% | 7106.6% | -133.7% | · | 21.8% | 24.4% | 2.0% | · | -15617.7% | |
| EBITDA Margin | · | · | · | · | · | · | · | -18187.7% | 7457.1% | -137.8% | · | 18.2% | 20.6% | -2.9% | · | -15849.6% | |
| ROA | -18.9% | -16.1% | · | -11.2% | -15.7% | -11.3% | · | -20.3% | -18.5% | -28.8% | · | 6.5% | 6.5% | 0.46% | · | -59.2% | |
| ROE | -21.3% | -17.4% | · | -13.0% | -19.3% | -13.7% | · | -23.7% | -22.4% | -35.1% | · | 7.4% | 7.6% | 0.53% | · | -74.7% | |
| ROIC | · | · | · | -10.8% | -25.5% | -18.8% | · | · | · | -37.7% | · | 4.2% | 4.8% | -0.65% | · | -37.9% |
流动性与偿付能力 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 12.1 | 17.9 | · | 13.7 | 8.7 | 12.1 | · | 4.5 | 4.7 | 4.5 | · | 9.5 | 6.7 | 7.5 | · | 5.3 | |
| Quick Ratio | 11.9 | 17.5 | · | 13.3 | 8.4 | 11.4 | · | 4.4 | 4.5 | 4.3 | · | 8.4 | 6.1 | 7.0 | · | 5.0 |
效率 3
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | 0.0 | 0.0 | 0.0 | · | 0.0 | -0.0 | 0.2 | · | 0.3 | 0.3 | 0.2 | · | 0.0 | |
| Inventory Turnover | · | · | · | · | · | · | · | · | · | · | · | 0.3 | 0.4 | 0.8 | · | 0.6 | |
| Receivables Turnover | · | · | · | 0.0 | 0.0 | 0.0 | · | 0.0 | -0.1 | 4.7 | · | 7.0 | 5.9 | 8.1 | · | 5.0 |
估值 (TTM) 10
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $416.0K | $416.0K | · | $416.0K | $-607.0K | $88M | · | $191M | $289M | $361M | · | $273M | · | · | · | · | |
| Net Income TTM | $-161M | $-153M | · | $-184M | $-223M | $-300M | · | $-243M | $-149M | $-74M | · | $-9M | $-84M | $-154M | · | $-179M | |
| Market Cap | $2.00B | $1.54B | · | $1.49B | $571M | $315M | · | $222M | $129M | $193M | · | $1.24B | $1.45B | $1.97B | · | $1.65B | |
| P/E | -11.3 | -8.6 | · | -5.9 | -2.1 | -0.8 | · | -0.9 | -0.9 | -2.5 | · | -63.1 | -14.2 | -10.6 | · | -4.5 | |
| P/S | 4808.1 | 3709.8 | · | 3585.9 | -941.5 | 3.6 | · | 1.2 | 0.4 | 0.5 | · | 4.5 | · | · | · | · | |
| P/B | 8.4 | 5.6 | · | 4.5 | 3.4 | 1.6 | · | 1.1 | 0.5 | 0.6 | · | 3.0 | 3.8 | 5.6 | · | 11.4 | |
| P / Tangible Book | 8.4 | 5.6 | · | 4.5 | 3.4 | 1.6 | · | 1.1 | 0.5 | 0.6 | · | 3.0 | 3.8 | 5.6 | · | 11.4 | |
| P / Cash Flow | · | -41.8 | · | · | · | -7.9 | · | · | · | -394.8 | · | · | · | -388.1 | · | · | |
| P / FCF | · | · | · | · | · | -7.9 | · | · | · | -347.2 | · | · | · | -369.9 | · | · | |
| Earnings Yield | -8.8% | -11.7% | · | -17.1% | -47.1% | -121.8% | · | -110.8% | -116.3% | -39.4% | · | -1.6% | -7.0% | -9.4% | · | -22.0% |
财务报表 损益表、资产负债表、现金流量表 — 年度，近5年
损益表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 收入 | $0 | $87M | $381M | $22M | $285.0K |
| 营业利润率 % | — | -360.2% | 10.2% | -905.7% | — |
| 净收入 | $-145M | $-302M | $49M | $-198M | $-88M |
| 稀释后每股收益 (EPS) | $-1.53 | $-4.43 | $0.70 | $-3.39 | $-13.35 |
资产负债表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 流动比率 | 14.3 | 6.7 | 5.7 | 8.2 | — |
| 速动比率 | 14.0 | 6.2 | 5.0 | 7.8 | — |
现金流
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 自由现金流 | $-123M | $-168M | $11M | $-182M | — |
我的指标 您的个人关注列表 — 来自完整基本面的选定行
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机构持有人 (13F) 228 家申报者 · $1.6B 总计 · 截至 2026年6月30日
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
机构活动 — Q2 2026 与上一季度对比
| 新仓位 | 已退出持仓 | 增加 | 减少 | 净股数变动 |
|---|---|---|---|---|
| 62 (+36 与上一季度对比) | 13 (-20 与上一季度对比) | 67 (0 与上一季度对比) | 63 (+12 与上一季度对比) | +3.5M |
与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天，外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过，优先显示最近一个已完整报告的季度对。
| 机构 | 价值 | 股份 | % 已追踪的13F | 类型 |
|---|---|---|---|---|
| FMR LLC | $261703547 | 14571467 | 16.32% | 股份 |
| PERCEPTIVE ADVISORS LLC | $149694481 | 8334882 | 9.34% | 股份 |
| TCG Crossover Management, LLC | $112138864 | 6243812 | 6.99% | 股份 |
| Commodore Capital LP | $101474000 | 5650000 | 6.33% | 股份 |
| Saturn V Capital Management LP | $83048854 | 4624101 | 5.18% | 股份 |
| VANGUARD CAPITAL MANAGEMENT LLC | $75867063 | 4224224 | 4.73% | 股份 |
| VANGUARD GROUP INC | $61683971 | 5106289 | 3.85% | 股份 |
| Driehaus Capital Management LLC | $54543981 | 3036970 | 3.40% | 股份 |
| First Light Asset Management, LLC | $54297678 | 3023256 | 3.39% | 股份 |
| STATE STREET CORP | $46755933 | 2603337 | 2.92% | 股份 |
| GEODE CAPITAL MANAGEMENT, LLC | $36185723 | 2014412 | 2.26% | 股份 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $34124000 | 1900000 | 2.13% | 股份 |
| GOLDMAN SACHS GROUP INC | $27615512 | 1537612 | 1.72% | 股份 |
| Siren, L.L.C. | $26591325 | 1480586 | 1.66% | 股份 |
| EVENTIDE ASSET MANAGEMENT, LLC | $23844428 | 1327536 | 1.49% | 股份 |
| 683 Capital Management, LLC | $22980036 | 1279512 | 1.43% | 股份 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $19065151 | 1061534 | 1.19% | 股份 |
| Alyeska Investment Group, L.P. | $18912149 | 1053015 | 1.18% | 股份 |
| Almitas Capital LLC | $17508863 | 974881 | 1.09% | 股份 |
| Jones Hill Capital LP | $16057282 | 894058 | 1.00% | 股份 |
| Woodline Partners LP | $15201111 | 846387 | 0.95% | 股份 |
| DIMENSIONAL FUND ADVISORS LP | $14544870 | 809848 | 0.91% | 股份 |
| Boxer Capital Management, LLC | $14368000 | 800000 | 0.90% | 股份 |
| Aberdeen Group plc | $13248553 | 737670 | 0.83% | 股份 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $13021539 | 725030 | 0.81% | 股份 |
| Connor, Clark & Lunn Investment Management Ltd. | $12949196 | 721002 | 0.81% | 股份 |
| GREAT POINT PARTNERS LLC | $12572000 | 700000 | 0.78% | 股份 |
| Balyasny Asset Management L.P. | $12302133 | 684974 | 0.77% | 股份 |
| Qube Research & Technologies Ltd | $12237746 | 681389 | 0.76% | 股份 |
| VANGUARD FIDUCIARY TRUST CO | $11190481 | 623078 | 0.70% | 股份 |
| TWO SIGMA INVESTMENTS, LP | $10658093 | 593435 | 0.66% | 股份 |
| BANK OF AMERICA CORP /DE/ | $9650357 | 537325 | 0.60% | 股份 |
| Rock Springs Capital Management LP | $8975761 | 499764 | 0.56% | 股份 |
| ADAR1 Capital Management, LLC | $8879029 | 494378 | 0.55% | 股份 |
| Nantahala Capital Management, LLC | $8740845 | 486684 | 0.55% | 股份 |
| Nearwater Capital Markets, Ltd | $7633000 | 425000 | 0.48% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $7279188 | 405300 | 0.45% | 买入期权 |
| Parkman Healthcare Partners LLC | $7162125 | 398782 | 0.45% | 股份 |
| HighVista Strategies LLC | $6933997 | 386080 | 0.43% | 股份 |
| STEMPOINT CAPITAL LP | $6902100 | 384304 | 0.43% | 股份 |
| Logos Global Management LP | $6286000 | 350000 | 0.39% | 股份 |
| Trexquant Investment LP | $6275924 | 349439 | 0.39% | 股份 |
| Ensign Peak Advisors, Inc | $5485720 | 305441 | 0.34% | 股份 |
| Tetragon Partners GP Ltd | $5350751 | 297926 | 0.33% | 股份 |
| JUPITER ASSET MANAGEMENT LTD | $4937994 | 274944 | 0.31% | 股份 |
| FIRST TRUST ADVISORS LP | $4572382 | 254587 | 0.29% | 股份 |
| JANE STREET GROUP, LLC | $4338992 | 241592 | 0.27% | 股份 |
| SummitTX Capital, L.P. | $4089312 | 227690 | 0.26% | 股份 |
| TWO SIGMA ADVISERS, LP | $3967084 | 328401 | 0.25% | 股份 |
| Cormorant Asset Management, LP | $3592000 | 200000 | 0.22% | 股份 |
| Aldebaran Capital, LLC | $3518220 | 195892 | 0.22% | 股份 |
| Walleye Capital LLC | $3351120 | 186588 | 0.21% | 股份 |
| ORBIMED ADVISORS LLC | $3293864 | 183400 | 0.21% | 股份 |
| BlackRock, Inc. | $3211122 | 178793 | 0.20% | 股份 |
| ACUTA CAPITAL PARTNERS, LLC | $3019345 | 168115 | 0.19% | 股份 |
| NORGES BANK | $2871804 | 159900 | 0.18% | 股份 |
| Alpha Wave Global, LP | $2791379 | 155422 | 0.17% | 股份 |
| Swiss National Bank | $2589832 | 144200 | 0.16% | 股份 |
| PFM Health Sciences, LP | $2580852 | 143700 | 0.16% | 股份 |
| AMERIPRISE FINANCIAL INC | $2253693 | 125484 | 0.14% | 股份 |
| Lighthouse Investment Partners, LLC | $2207446 | 122909 | 0.14% | 股份 |
| Ikarian Capital, LLC | $2110301 | 117500 | 0.13% | 股份 |
| RHUMBLINE ADVISERS | $2028032 | 112920 | 0.13% | 股份 |
| ALPS ADVISORS INC | $2019548 | 112447 | 0.13% | 股份 |
| Elmind Capital, LP | $2011520 | 112000 | 0.13% | 股份 |
| Campbell & CO Investment Adviser LLC | $1813295 | 100963 | 0.11% | 股份 |
| Affinity Asset Advisors, LLC | $1778022 | 98999 | 0.11% | 股份 |
| Bank of New York Mellon Corp | $1759164 | 97949 | 0.11% | 股份 |
| 683 Capital Management, LLC | $1734936 | 96600 | 0.11% | 买入期权 |
| Quantinno Capital Management LP | $1452066 | 80850 | 0.09% | 股份 |
| ALLIANCEBERNSTEIN L.P. | $1451160 | 104400 | 0.09% | 股份 |
| 1492 Capital Management LLC | $1432328 | 79751 | 0.09% | 股份 |
| JPMORGAN CHASE & CO | $1325363 | 70875 | 0.08% | 股份 |
| CITADEL ADVISORS LLC | $1206409 | 67172 | 0.08% | 股份 |
| Schonfeld Strategic Advisors LLC | $1199799 | 66804 | 0.07% | 股份 |
| WELLINGTON MANAGEMENT GROUP LLP | $1195382 | 66558 | 0.07% | 股份 |
| CITIGROUP INC | $1138251 | 63377 | 0.07% | 股份 |
| STATE OF WISCONSIN INVESTMENT BOARD | $1100553 | 61278 | 0.07% | 股份 |
| JANE STREET GROUP, LLC | $1079396 | 60100 | 0.07% | 卖出期权 |
| Corient Private Wealth LP | $1065424 | 59322 | 0.07% | 股份 |
| Moody Aldrich Partners LLC | $1038124 | 57802 | 0.06% | 股份 |
| VANGUARD ASSET MANAGEMENT, Ltd | $1022786 | 56948 | 0.06% | 股份 |
| MetLife Investment Management, LLC | $1000372 | 55700 | 0.06% | 股份 |
| D. E. Shaw & Co., Inc. | $979485 | 54537 | 0.06% | 股份 |
| BARCLAYS PLC | $968350 | 53917 | 0.06% | 股份 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $903528 | 65002 | 0.06% | 股份 |
| FEDERATED HERMES, INC. | $903478 | 50305 | 0.06% | 股份 |
| Hudson Bay Capital Management LP | $898000 | 50000 | 0.06% | 股份 |
| Vanguard Global Advisers, LLC | $859404 | 47851 | 0.05% | 股份 |
| FOX RUN MANAGEMENT, L.L.C. | $804913 | 44817 | 0.05% | 股份 |
| Allostery Investments LP | $769963 | 120119 | 0.05% | 股份 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $760624 | 42351 | 0.05% | 股份 |
| ADAR1 Capital Management, LLC | $720196 | 40100 | 0.04% | 卖出期权 |
| Aquatic Capital Management LLC | $708073 | 39425 | 0.04% | 股份 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $679391 | 37828 | 0.04% | 股份 |
| Invesco Ltd. | $660443 | 36773 | 0.04% | 股份 |
| BOOTHBAY FUND MANAGEMENT, LLC | $647638 | 36060 | 0.04% | 股份 |
| JENNISON ASSOCIATES LLC | $643705 | 35841 | 0.04% | 股份 |
| TUDOR INVESTMENT CORP ET AL | $635964 | 35410 | 0.04% | 股份 |
| NEW YORK STATE COMMON RETIREMENT FUND | $616028 | 34300 | 0.04% | 股份 |
公司内部人士 15 位内幕人士 · 7 位高管 · 8 位董事
| 内部人士 | 角色 | 上次活动 | 持股数量 | 买入 12个月 | 卖出 12个月 | 净额 12个月 |
|---|---|---|---|---|---|---|
| Joshua B Cohen | Co-Chief Executive Officer | 2026年3月5日 A | 3583548 | 0 | 7 | $-3044636 |
| Justin B. Klee | Co-Chief Executive Officer | 2026年3月5日 A | 3583481 | 0 | 7 | $-3044891 |
| James M Frates | Chief Financial Officer | 2026年3月5日 A | 261628 | 0 | 4 | $-358576 |
| Gina Mazzariello | Chief Legal Officer | 2026年7月10日 S | 179090 | 0 | 6 | $-865895 |
| Camille L Bedrosian | Chief Medical Officer | 2026年3月5日 A | 265285 | 0 | 3 | $-364153 |
| Patrick D Yeramian | Chief Medical Officer | 2024年1月9日 S | 205605 | 0 | 0 | $0 |
| Margaret Olinger | Chief Commercial Officer | 2023年12月27日 M | 276108 | 0 | 0 | $0 |
| Bernhardt G Zeiher | 董事 | 2026年6月4日 A | 10000 | 0 | 0 | $0 |
| Karen Firestone | 董事 | 2026年6月4日 A | 66900 | 2 | 0 | $152183 |
| Paul R. Fonteyne | 董事 | 2026年6月4日 A | 3947 | 0 | 0 | $0 |
| Daphne Quimi | 董事 | 2026年6月4日 A | 5000 | 0 | 0 | $0 |
| George M Milne JR | 董事 | 2026年6月4日 A | 812881 | 0 | 0 | $0 |
| Isaac Cheng | 董事 | 2022年6月9日 A | 6578 | 0 | 0 | $0 |
| Morningside Venture Investments Ltd | 10% 所有者 | 2023年8月15日 G | 4997302 | 0 | 0 | $0 |
| ALS Invest 1 B.V. | 10% 所有者 | 2022年7月6日 S | 5895280 | 0 | 0 | $0 |
来自SEC表格3/4/5申报的内部人士；净额=仅公开市场买卖
激进投资者及 5%+ 股东 1 持仓
提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权，意图影响发行人（激进股东持股、董事会活动、并购）。每一行显示该申报人持仓的最新已知状态。
| 申报人 | 已申报 | 持股 | 状态 | 目的 | 申报 |
|---|---|---|---|---|---|
| Morningside Venture Investments Limited (2), MVIL, LLC (2), Frances Anne Elizabeth Richard (2), Jill Marie Franklin (2), Peter Stuart Allenby Edwards (2), Cheung Ka Ho (2), Cheng Yee Wing Betty (2), Wong See Wai (2) ×5 申报 | 2023年10月4日 | — | 初始申报 | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF持仓 由 50 只交易所交易基金持有
权重仅反映直接股权持仓（N-PORT）；杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。
| 基金 | 权重 | 单位 | 截至 | 来源 |
|---|---|---|---|---|
| PILL · Direxion Shares ETF Trust | 1.43% | 11556 NS | 2026年4月30日 | N-PORT |
| SBIO · ALPS ETF Trust | 1.01% | 113933 NS | 2026年5月31日 | N-PORT |
| BBC · ETFis Series Trust I | 0.90% | 21068 NS | 2026年4月30日 | N-PORT |
| FMED · Fidelity Covington Trust | 0.82% | 23554 NS | 2026年5月31日 | N-PORT |
| IHE · iShares Trust | 0.45% | 301742 SH | 2026年8月8日 | 每日 |
| FYC · First Trust Exchange-Traded Alpha... | 0.26% | 168022 NS | 2026年4月30日 | N-PORT |
| FSCC · Federated Hermes ETF Trust | 0.25% | 47310 NS | 2026年5月31日 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trus... | 0.17% | 6054 SH | 2026年8月8日 | 每日 |
| IBB · iShares Trust | 0.17% | 680529 SH | 2026年8月8日 | 每日 |
| IWO · iShares Trust | 0.14% | 828258 SH | 2026年8月8日 | 每日 |
| VFMO · VANGUARD WELLINGTON FUND | 0.13% | 145454 SH | 2026年8月8日 | 每日 |
| FFSM · FIDELITY COVINGTON TRUST | 0.10% | 82935 NS | 2026年4月30日 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.10% | 98590 SH | 2026年8月8日 | 每日 |
| ESSC · Strategy Shares | 0.10% | 1602 NS | 2026年4月30日 | N-PORT |
| ESML · iShares Trust | 0.09% | 104336 SH | 2026年8月8日 | 每日 |
| NUSC · Nushares ETF Trust | 0.09% | 69649 NS | 2026年4月30日 | N-PORT |
| BIB · ProShares Trust | 0.08% | 4059 NS | 2026年5月31日 | N-PORT |
| IWM · iShares Trust | 0.07% | 2325160 SH | 2026年8月8日 | 每日 |
| BBSC · J.P. Morgan Exchange-Traded Fund ... | 0.07% | 30496 NS | 2026年4月30日 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.07% | 83712 SH | 2026年8月8日 | 每日 |
| FYX · First Trust Exchange-Traded Alpha... | 0.07% | 49811 NS | 2026年4月30日 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0.06% | 43655 NS | 2026年5月31日 | N-PORT |
| ISCV · iShares Trust | 0.06% | 18288 SH | 2026年8月8日 | 每日 |
| FAD · First Trust Exchange-Traded Alpha... | 0.05% | 15666 NS | 2026年4月30日 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.05% | 529383 SH | 2026年8月8日 | 每日 |
| SMLF · iShares Trust | 0.05% | 87250 SH | 2026年8月8日 | 每日 |
| RSSL · Global X Funds | 0.04% | 39313 NS | 2026年4月30日 | N-PORT |
| ITWO · ProShares Trust | 0.03% | 4300 NS | 2026年5月31日 | N-PORT |
| ISCB · iShares Trust | 0.03% | 3700 SH | 2026年8月8日 | 每日 |
| SCHA · SCHWAB STRATEGIC TRUST | 0.03% | 402853 NS | 2026年5月31日 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.02% | 966947 SH | 2026年8月8日 | 每日 |
| VHT · VANGUARD WORLD FUND | 0.02% | 216297 SH | 2026年8月8日 | 每日 |
| UWM · ProShares Trust | 0.02% | 3363 NS | 2026年5月31日 | N-PORT |
| WSML · iShares Trust | 0.02% | 4961 SH | 2026年8月8日 | 每日 |
| DFAS · Dimensional ETF Trust | 0.02% | 150411 NS | 2026年4月30日 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0.02% | 30218 NS | 2026年4月30日 | N-PORT |
| URTY · ProShares Trust | 0.01% | 3404 NS | 2026年5月31日 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0.01% | 3710 NS | 2026年5月31日 | N-PORT |
| HDG · ProShares Trust | 0.01% | 85 NS | 2026年5月31日 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0.01% | 39887 NS | 2026年5月31日 | N-PORT |
| ITOT · iShares Trust | 0.00% | 115613 SH | 2026年8月8日 | 每日 |
| IWV · iShares Trust | 0.00% | 23926 SH | 2026年8月8日 | 每日 |
| DCOR · Dimensional ETF Trust | 0.00% | 4500 NS | 2026年4月30日 | N-PORT |
| DFAC · Dimensional ETF Trust | 0.00% | 54057 NS | 2026年4月30日 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0.00% | 58783 NS | 2026年5月31日 | N-PORT |
| DFAU · Dimensional ETF Trust | 0.00% | 13188 NS | 2026年4月30日 | N-PORT |
| DFUS · Dimensional ETF Trust | 0.00% | 8949 NS | 2026年4月30日 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 3154723 SH | 2026年8月8日 | 每日 |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 7178 SH | 2026年8月8日 | 每日 |
| DXUV · Dimensional ETF Trust | 0.00% | 8 NS | 2026年4月30日 | N-PORT |