IONS Ionis Pharmaceuticals, Inc. - Common Stock
$60.34
价格 · 八月 19, 2026
截至...的财报数据 七月 29, 2026
52周区间
$42–$87
41% of range
分析师评级
BUY
31 analysts
目标价
$89
+48% upside
P/E (TTM)
-25.4
ROE
-68.1%
净利润率
—
IONS 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围
价格
$60.34
市值
$9.85B
P/E (TTM)
-25.4
每股收益 (TTM)
$-2.38
营收 (TTM)
—
股息收益率
—
ROE
-68.1%
负债/权益
3.6
52周区间
$42 – $87
IONS 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图
Configure
10年表现 收入、净利润、利润率和每股收益趋势
营收与净利润
—
2016-12-31
→
2017-12-31
EPS
$-2.38
2016-12-31
→
2025-12-31
自由现金流
$-320M
2016-12-31
→
2025-12-31
利润率
—
估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜？
指标
5年趋势
IONS
同行中位数
P/E (TTM)
-25.4
16.0
P/S (TTM) (市销率 (TTM))
10.4
32.5
P/B (市净率)
20.1
3.9
EV / EBITDA (企业价值 / EBITDA)
-23.4
—
Price / FCF (股价/自由现金流)
-30.8
—
盈利能力 毛利率、营业利润率和净利率；股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)
指标
5年趋势
IONS
同行中位数
ROA
-11.7%
-22.2%
ROE
-68.1%
-37.6%
ROIC
-17.1%
—
财务健康 债务、流动性、偿付能力 — 资产负债表强度
指标
5年趋势
IONS
同行中位数
Debt / Equity (负债/股东权益比率)
3.6
0.0
Current Ratio (流动比率)
3.8
5.7
Quick Ratio (速动比率)
3.4
—
成长 营收、每股收益 (EPS) 和净利润增长：同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)
指标
5年趋势
IONS
同行中位数
资本效率 资产周转率、库存周转率、应收账款周转率
指标
5年趋势
IONS
同行中位数
IONS 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间
买入
31 位分析师
- 强烈买入 8 25.8%
- 买入 17 54.8%
- 持有 6 19.4%
- 卖出 0 0.0%
- 强烈卖出 0 0.0%
12个月价格目标
21 位分析师 · 2026-08-18
中位数
$90.00
← 低于所有目标
$60.34
最低
$66.00
最高
$115.00
中位数目标
$90.00
+49.2%
平均目标
$89.33
+48.1%
收益历史 每股收益实际值 vs 预估值，惊喜%，达标率，下次财报日期
平均惊喜
0.42%
| 期间 | EPS Actual | EPS 预期 | 惊喜 |
|---|---|---|---|
| 2026年6月30日 | $-0.69 | $-1.09 | 0.40% |
| 2026年3月31日 | $-0.56 | $-0.93 | 0.37% |
| 2025年12月31日 | $-1.41 | $-1.35 | -0.06% |
| 2025年9月30日 | $-0.80 | $-1.26 | 0.46% |
| 2025年6月30日 | $0.70 | $-0.44 | 1.1% |
| 2025年3月31日 | $-0.93 | $-1.14 | 0.21% |
同行比较（GICS 子行业） 关键指标与行业同行对比
| 股票代码 | 市值 | P/E | 营收同比增长 | 净利润率 | ROE | 毛利率 |
|---|---|---|---|---|---|---|
| IONS | $12.92B | -33.2 | — | — | -68.1% | — |
| APGE | $5.16B | -17.9 | — | — | — | — |
| PTGX | $5.47B | -42.6 | -89.4% | -282.8% | -20.3% | — |
| KYMR | $6.33B | -21.1 | -16.7% | -794.0% | -24.4% | — |
| KRYS | $7.20B | 36.0 | 33.9% | 52.6% | 18.1% | — |
| SYRE | $2.56B | 10.1 | -62.0% | — | -26.5% | — |
| PCVX | $6.05B | -8.2 | — | — | -26.6% | — |
| IMVT | $5.07B | -9.0 | 229.2% | — | -73.7% | — |
| IBRX | $2.00B | -5.2 | 668.3% | -310.2% | 71.0% | — |
完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表
损益表 16
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | · | · | · | $508M | $347M | $284M | $214M | |
| Cost of Revenue | $16M | $11M | $9M | $14M | $11M | $12M | $4M | $2M | $0 | $0 | · | · | |
| R&D Expense | $916M | $902M | $900M | · | $638M | $531M | $462M | $412M | $372M | $340M | $320M | $239M | |
| SG&A Expense | $394M | $267M | $233M | $150M | $186M | $354M | $287M | $245M | $108M | $49M | $37M | $20M | |
| Operating Expenses | $1.33B | $1.18B | $1.14B | $998M | $841M | $901M | $757M | $661M | $483M | $393M | $359M | $262M | |
| Operating Income | $-382M | $-475M | $-354M | $-410M | $-30M | $-172M | $366M | $-61M | $31M | $-20M | $-76M | $-48M | |
| Interest Expense | $17M | $17M | $13M | $8M | $9M | $10M | $12M | $45M | $45M | $39M | $37M | $22M | |
| Other Non-op | $-15M | $1M | $14M | $-7M | $-10M | $-62.0K | $-686.0K | $-182.0K | $-4M | $0 | · | · | |
| Pretax Income | $-380M | $-460M | $-334M | $-258M | $-29M | $-135M | $339M | $-76M | $-17M | $-57M | $-88M | $-54M | |
| Income Tax | $2M | $-6M | $32M | $12M | $-551.0K | $345M | $52M | $-291M | $-6M | $3M | $372.0K | $-15M | |
| Net Income | $-381M | $-454M | $-366M | $-270M | $-29M | $-444M | $278M | $274M | $346.0K | $-60M | $-88M | $-39M | |
| EPS (Basic) | $-2.38 | $-3.04 | $-2.56 | $-1.90 | $-0.20 | $-3.18 | $2.00 | $2.09 | $0.15 | $-0.50 | $-0.74 | · | |
| EPS (Diluted) | $-2.38 | $-3.04 | $-2.56 | $-1.90 | $-0.20 | $-3.18 | $1.90 | $2.07 | $0.15 | $-0.50 | $-0.74 | · | |
| Shares (Basic) | 160,010,000 | 149,514,000 | 143,190,000 | 141,848,000 | 141,021,000 | 139,612,000 | 139,998,000 | 132,320,000 | 124,016,000 | 120,933,000 | 119,719,000 | · | |
| Shares (Diluted) | 160,010,000 | 149,514,000 | 143,190,000 | 141,848,000 | 141,021,000 | 139,612,000 | 153,164,000 | 134,056,000 | 126,098,000 | 120,933,000 | 119,719,000 | · | |
| EBITDA | $-382M | $-475M | $-354M | $-410M | $-30M | $-172M | $366M | $-61M | $25M | $-46M | $-76M | $-48M |
资产负债表 24
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $372M | $242M | $399M | $276M | $869M | $398M | $683M | $279M | $130M | $85M | $129M | $143M | |
| Short-term Investments | $2.31B | $2.06B | $1.93B | $1.71B | $1.25B | · | · | · | · | · | · | · | |
| Inventory | $10M | $13M | $7M | $22M | $25M | $22M | $18M | $9M | $10M | · | · | · | |
| Other Current Assets | $237M | $218M | $205M | $168M | $143M | $140M | $140M | $102M | $73M | $17M | $15M | $16M | |
| Current Assets | $2.99B | $2.62B | $2.64B | $2.20B | $2.35B | $2.13B | $2.72B | $2.21B | $1.17B | $798M | $837M | $837M | |
| PP&E (Net) | $123M | $94M | $71M | $74M | $178M | $181M | $154M | $132M | $122M | $93M | $90M | $89M | |
| Accum. Depreciation | $109M | $106M | $97M | $88M | $103M | $87M | $74M | $61M | $88M | $80M | $73M | $66M | |
| Intangibles | · | · | · | · | $29M | $28M | $26M | $24M | $22M | $20M | · | · | |
| Other Non-current Assets | $172M | $127M | $105M | $75M | $71M | $50M | $28M | $13M | $10M | $1M | · | · | |
| Total Assets | $3.52B | $3.00B | $2.99B | $2.53B | $2.61B | $2.39B | $3.23B | $2.67B | $1.32B | $912M | $948M | $956M | |
| Accounts Payable | $28M | $43M | $26M | $18M | $12M | $17M | $16M | $29M | $25M | $21M | $28M | $18M | |
| Accrued Liabilities | $106M | $108M | $148M | $140M | $89M | $90M | $67M | $48M | $67M | $36M | $28M | $30M | |
| Current Liabilities | $782M | $309M | $448M | $312M | $241M | $599M | $273M | $280M | $244M | $134M | $149M | $115M | |
| Capital Leases | $262M | $162M | $171M | $179M | $19M | · | · | · | · | · | · | · | |
| Other Non-current Liabilities | $28M | $52M | $42M | $16M | $7M | · | · | · | · | · | · | · | |
| Total Liabilities | $3.03B | $2.42B | $2.60B | $1.96B | $1.84B | $1.65B | $1.55B | $1.48B | $957M | $813M | $747M | $698M | |
| Long-term Debt | $1.81B | $1.25B | $1.31B | $1.19B | · | · | · | · | · | · | · | · | |
| Total Debt | $1.76B | $1.20B | $1.24B | $1.18B | · | · | · | · | · | · | · | · | |
| Common Stock | $163.0K | $158.0K | $144.0K | $142.0K | $141.0K | $140.0K | $140.0K | $138.0K | $125.0K | $122.0K | $120.0K | $118.0K | |
| Retained Earnings | $-2.63B | $-2.25B | $-1.80B | $-1.43B | $-1.16B | $-1.13B | $-708M | $-967M | $-1.24B | $-1.18B | $-1.09B | $-1.01B | |
| AOCI | $-25M | $-31M | $-33M | $-57M | $-33M | $-21M | $-25M | $-32M | $-32M | $-30M | $-14M | $40M | |
| Stockholders' Equity | $489M | $588M | $387M | $573M | $772M | $743M | $1.47B | $1.05B | $281M | $100M | $201M | $258M | |
| Liabilities + Equity | $3.52B | $3.00B | $2.99B | $2.53B | $2.61B | $2.39B | $3.23B | $2.67B | $1.32B | $912M | $948M | $956M | |
| Shares Outstanding | 163,304,875 | 157,908,815 | 144,340,526 | 142,057,736 | 141,210,015 | 140,365,594 | 140,339,615 | 137,928,828 | 124,976,373 | 121,636,273 | 120,351,480 | 118,442,726 |
现金流 14
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $134M | $130M | $106M | $100M | $121M | $230M | $147M | $131M | $86M | $72M | $59M | $31M | |
| Deferred Tax | $0 | $0 | $0 | $0 | $0 | $342M | $904.0K | $-291M | $0 | $0 | $0 | $-11M | |
| Amort. of Intangibles | $2M | $2M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | · | · | |
| Operating Cash Flow | $-269M | $-501M | $-308M | $-274M | $31M | $36M | $346M | $603M | $174M | $-112M | $21M | $6M | |
| CapEx | $51M | $45M | $24M | $16M | $12M | $35M | $31M | $14M | $35M | $7M | $8M | $8M | |
| Investing Cash Flow | $-278M | $-134M | $-214M | $-263M | $195M | $274M | $-41M | $-930M | $-358M | $57M | $-60M | · | |
| Stock Issued | $0 | $489M | $0 | $0 | · | $0 | $0 | $448M | $72M | $0 | $0 | $0 | |
| Stock Repurchased | · | · | · | $0 | $0 | $91M | $34M | $0 | $0 | · | · | · | |
| Net Stock Activity | $0 | $489M | · | $0 | $0 | $-91M | $-34M | · | $72M | · | $0 | $0 | |
| Financing Cash Flow | $676M | $478M | $644M | $-55M | $246M | $-597M | $100M | $476M | $229M | $11M | $25M | · | |
| Net Change in Cash | $130M | $-157M | $123M | $-593M | $472M | $-286M | $404M | $149M | $45M | $-44M | $-14M | · | |
| Taxes Paid | $-639.0K | $-6M | $48M | $5M | · | $26M | $9M | $0 | $0 | · | · | · | |
| Free Cash Flow | $-320M | $-546M | $-331M | $-290M | $19M | $772.0K | $315M | $589M | $139M | $-119M | $13M | $-1M | |
| Levered FCF | $-337M | $-563M | $-345M | $-299M | $10M | $-128M | $272M | $716M | $106M | $-159M | $-23M | $-17M |
盈利能力 7
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | · | 4.8% | -13.4% | -26.7% | -22.3% | |
| Net Margin | · | · | · | · | · | · | · | · | -1.2% | -25.0% | -31.1% | -18.2% | |
| Pretax Margin | · | · | · | · | · | · | · | · | -4.6% | -24.1% | -31.0% | -25.4% | |
| EBITDA Margin | · | · | · | · | · | · | · | · | 4.8% | -13.4% | -26.7% | -22.3% | |
| ROA | -11.7% | -15.2% | -13.3% | -10.5% | -1.1% | -16.1% | 10.0% | 13.7% | -0.53% | -9.3% | -9.2% | -4.3% | |
| ROE | -68.1% | -71.9% | -104.3% | -40.1% | -3.8% | -39.0% | 23.4% | 41.2% | -2.8% | -57.6% | -38.5% | -12.3% | |
| ROIC | -17.1% | -26.0% | -23.8% | -24.5% | -3.8% | -58.4% | 21.8% | 16.5% | 5.5% | -48.1% | -37.9% | -13.3% |
流动性与偿付能力 5
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.8 | 8.5 | 5.9 | 7.1 | 9.7 | 3.7 | 10.0 | 7.9 | 5.2 | 6.0 | 5.6 | 7.3 | |
| Quick Ratio | 3.4 | 7.4 | 5.2 | 6.4 | 3.6 | 0.7 | 2.5 | 1.0 | 0.6 | 0.6 | 0.9 | 1.2 | |
| Debt / Equity | 3.6 | 2.0 | 3.2 | 2.1 | · | · | · | · | · | · | · | · | |
| LT Debt / Equity | 2.7 | 2.0 | 3.2 | 2.1 | · | · | · | · | · | · | · | · | |
| Interest Coverage | -22.1 | -28.0 | -27.9 | -50.5 | -3.2 | -3.8 | 7.5 | -1.4 | 0.5 | -1.2 | -2.1 | -2.1 |
效率 2
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | · | · | · | 0.5 | 0.4 | 0.3 | 0.2 | |
| Inventory Turnover | 1.4 | 1.1 | 0.4 | 0.6 | 0.5 | 0.6 | 0.3 | 0.2 | · | · | · | · |
估值 (TTM) 14
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $944M | $705M | $788M | $587M | $810M | $729M | $1.12B | $600M | $508M | $347M | $284M | $214M | |
| Net Income TTM | $-381M | $-454M | $-366M | $-270M | $-29M | $-444M | $278M | $274M | $346.0K | $-60M | $-88M | $-39M | |
| Market Cap | $12.92B | $5.52B | $7.30B | $5.37B | $4.30B | $7.94B | $8.48B | $7.46B | $6.29B | $5.82B | $7.45B | $7.31B | |
| Enterprise Value | $12.00B | $4.43B | $6.21B | $4.55B | · | · | · | · | · | · | · | · | |
| P/E | -33.2 | -11.5 | -19.8 | -19.9 | -152.2 | -17.8 | 31.8 | 26.1 | 335.3 | -95.7 | -83.7 | -176.4 | |
| P/S | 13.7 | 7.8 | 9.3 | 9.1 | 5.3 | 10.9 | 7.6 | 12.4 | 12.4 | 16.8 | 26.3 | 34.1 | |
| P/B | 26.4 | 9.2 | 18.9 | 9.4 | 5.6 | 9.4 | 5.8 | 7.1 | 19.0 | 58.4 | 37.1 | 28.4 | |
| P / Tangible Book | 26.4 | 9.4 | 18.9 | 9.4 | 5.8 | 11.1 | · | · | · | · | · | · | |
| P / Cash Flow | -48.1 | -11.0 | -23.7 | -19.6 | 139.5 | 221.1 | 24.5 | 12.4 | 36.1 | -51.9 | 352.8 | 1163.5 | |
| P / FCF | -40.4 | -10.1 | -22.0 | -18.5 | 228.0 | 10280.1 | 26.9 | 12.7 | 45.1 | -48.8 | 554.9 | -5930.8 | |
| EV / EBITDA | -31.4 | -9.3 | -17.6 | -11.1 | · | · | · | · | · | · | · | · | |
| EV / FCF | -37.5 | -8.1 | -18.7 | -15.7 | · | · | · | · | · | · | · | · | |
| EV / Revenue | 12.7 | 6.3 | 7.9 | 7.8 | · | · | · | · | · | · | · | · | |
| Earnings Yield | -3.0% | -8.7% | -5.1% | -5.0% | -0.66% | -5.6% | 3.1% | 3.8% | 0.30% | -1.1% | -1.2% | -0.57% |
损益表 15
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $268M | $246M | $203M | $157M | $452M | $132M | $227M | $134M | $225M | $119M | $325M | $144M | $188M | $131M | $152M | $160M | |
| Cost of Revenue | $3M | $3M | $8M | $2M | $4M | $1M | $4M | $1M | $4M | $2M | $3M | $2M | $3M | $1M | $4M | $2M | |
| SG&A Expense | $150M | $150M | $130M | $97M | $91M | $76M | $88M | $62M | $65M | $53M | $71M | $70M | $46M | $46M | $48M | $34M | |
| Operating Expenses | $370M | $364M | $418M | $317M | $312M | $278M | $337M | $282M | $291M | $269M | $331M | $287M | $279M | $245M | $360M | $219M | |
| Operating Income | $-102M | $-117M | $-214M | $-160M | $140M | $-147M | $-111M | $-149M | $-66M | $-150M | $-6M | $-143M | $-90M | $-114M | $-208M | $-59M | |
| Interest Expense | $5M | $5M | $5M | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $5M | $4M | $2M | $2M | $2M | $2M | |
| Other Non-op | $987.0K | $-456.0K | $-16M | $363.0K | $102.0K | $465.0K | $302.0K | $142.0K | $610.0K | $277.0K | $235.0K | $2M | $11M | $230.0K | $123.0K | $5M | |
| Pretax Income | $-113M | $-92M | $-228M | $-128M | $124M | $-147M | $-107M | $-144M | $-66M | $-143M | $-3M | $-141M | $-77M | $-113M | $-44M | $-47M | |
| Income Tax | $1M | $218.0K | $1M | $213.0K | $-20.0K | $116.0K | $-3M | $-4M | $64.0K | $75.0K | $6M | $7M | $8M | $11M | $8M | $283.0K | |
| Net Income | $-115M | $-93M | $-229M | $-129M | $124M | $-147M | $-104M | $-140M | $-66M | $-143M | $-9M | $-147M | $-85M | $-124M | $-52M | $-47M | |
| EPS (Basic) | $-0.69 | $-0.56 | $-1.41 | $-0.80 | $0.78 | $-0.93 | $-0.66 | $-0.95 | $-0.45 | $-0.98 | $-0.06 | $-1.03 | $-0.60 | $-0.87 | $-0.37 | $-0.33 | |
| EPS (Diluted) | $-0.69 | $-0.56 | $-1.41 | $-0.80 | $0.70 | $-0.93 | $-0.66 | $-0.95 | $-0.45 | $-0.98 | $-0.06 | $-1.03 | $-0.60 | $-0.87 | $-0.37 | $-0.33 | |
| Shares (Basic) | 165,419,000 | 164,874,000 | -317,627,000 | 159,765,000 | 159,137,000 | 158,735,000 | -290,575,000 | 148,593,000 | 145,958,000 | 145,538,000 | -285,960,000 | 143,317,000 | 143,098,000 | 142,735,000 | -283,495,000 | 141,950,000 | |
| Shares (Diluted) | 165,419,000 | 164,874,000 | -340,821,000 | 159,765,000 | 182,331,000 | 158,735,000 | -290,575,000 | 148,593,000 | 145,958,000 | 145,538,000 | -285,960,000 | 143,317,000 | 143,098,000 | 142,735,000 | -283,495,000 | 141,950,000 | |
| EBITDA | $-102M | $-117M | · | $-160M | $140M | $-147M | · | $-149M | $-66M | $-150M | · | $-143M | $-90M | $-114M | · | $-59M |
资产负债表 23
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $350M | $173M | $372M | $338M | $297M | $264M | $242M | $335M | $294M | $349M | · | $352M | $425M | $309M | · | $315M | |
| Short-term Investments | $1.70B | $1.75B | $2.31B | $1.90B | $1.99B | $1.88B | $2.06B | $2.15B | $1.78B | $1.86B | · | $1.88B | $1.96B | $2.04B | · | $1.67B | |
| Inventory | $51M | $6M | $10M | $10M | $8M | $12M | $13M | $28M | $29M | $30M | · | $26M | $26M | $22M | · | $21M | |
| Other Current Assets | $327M | $306M | $237M | $244M | $226M | $223M | $218M | $184M | $195M | $174M | · | $181M | $178M | $160M | · | $143M | |
| Current Assets | $2.49B | $2.94B | $2.99B | $2.52B | $2.58B | $2.42B | $2.62B | $2.71B | $2.33B | $2.42B | · | $2.58B | $2.62B | $2.54B | · | $2.15B | |
| PP&E (Net) | $155M | $142M | $123M | $106M | $112M | $103M | $94M | $83M | $76M | $73M | · | $71M | $92M | $85M | · | $181M | |
| Accum. Depreciation | · | · | $109M | · | · | · | $106M | · | · | · | · | · | · | · | · | · | |
| Intangibles | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $30M | |
| Other Non-current Assets | $117M | $136M | $172M | $166M | $132M | $132M | $127M | $120M | $119M | $106M | · | $104M | $86M | $78M | · | $59M | |
| Total Assets | $2.99B | $3.45B | $3.52B | $3.03B | $2.99B | $2.81B | $3.00B | $3.08B | $2.69B | $2.76B | · | $2.93B | $2.97B | $2.89B | · | $2.42B | |
| Accounts Payable | $48M | $26M | $28M | $14M | $23M | $17M | $43M | $9M | $9M | $13M | · | $6M | $24M | $10M | · | $21M | |
| Accrued Liabilities | $116M | $127M | $106M | $99M | $99M | $103M | $108M | $124M | $114M | $106M | · | $119M | $105M | $113M | · | $128M | |
| Current Liabilities | $316M | $717M | $782M | $903M | $897M | $250M | $309M | $305M | $306M | $328M | · | $404M | $288M | $259M | · | $283M | |
| Capital Leases | $262M | $259M | $262M | $263M | $164M | $159M | $162M | $168M | $166M | $169M | · | $173M | $175M | $177M | · | · | |
| Other Non-current Liabilities | $28M | $28M | · | $29M | $59M | $56M | · | $42M | $42M | $42M | · | $49M | $16M | $7M | · | · | |
| Total Liabilities | $2.55B | $2.96B | $3.03B | $2.42B | $2.35B | $2.34B | $2.42B | $2.42B | $2.43B | $2.47B | · | $2.62B | $2.54B | $2.40B | · | $1.83B | |
| Long-term Debt | · | · | $1.81B | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Common Stock | $166.0K | $166.0K | $163.0K | $161.0K | $159.0K | $159.0K | $158.0K | $158.0K | $146.0K | $146.0K | · | $143.0K | $143.0K | $143.0K | · | $142.0K | |
| Retained Earnings | $-2.84B | $-2.72B | $-2.63B | $-2.40B | $-2.27B | $-2.40B | $-2.25B | $-2.15B | $-2.00B | $-1.94B | · | $-1.79B | $-1.64B | $-1.55B | · | $-1.38B | |
| AOCI | $-34M | $-31M | $-25M | $-26M | $-28M | $-29M | $-31M | $-24M | $-35M | $-35M | · | $-46M | $-51M | $-49M | · | $-63M | |
| Stockholders' Equity | $440M | $491M | $489M | $618M | $632M | $476M | $588M | $662M | $264M | $297M | $387M | $315M | $428M | $487M | $573M | $594M | |
| Liabilities + Equity | $2.99B | $3.45B | $3.52B | $3.03B | $2.99B | $2.81B | $3.00B | $3.08B | $2.69B | $2.76B | · | $2.93B | $2.97B | $2.89B | · | $2.42B | |
| Shares Outstanding | 165,636,792 | 165,902,064 | 163,304,875 | 161,137,930 | 159,196,782 | 159,041,259 | 157,908,815 | 157,813,136 | 146,025,246 | 145,844,719 | · | 143,393,493 | 143,167,414 | 143,022,539 | · | 142,017,411 |
现金流 11
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $46M | $43M | $43M | $31M | $30M | $30M | $36M | $32M | $31M | $31M | $26M | $26M | $27M | $27M | $26M | $24M | |
| Amort. of Intangibles | $700.0K | $661.0K | $638.0K | $621.0K | $598.0K | $582.0K | $459.0K | $617.0K | $621.0K | $639.0K | $655.0K | $660.0K | $637.0K | $607.0K | $610.0K | $608.0K | |
| Operating Cash Flow | $566M | $-793M | $-138M | $-131M | $151M | $-151M | $-116M | $-115M | $-120M | $-150M | $33M | $-109M | $-97M | $-134M | $-200M | $-24M | |
| CapEx | $16M | $22M | $21M | $5M | $12M | $13M | $25M | $9M | $6M | $4M | $-819.0K | $2M | $12M | $10M | $4M | $6M | |
| Investing Cash Flow | $23M | $537M | $-420M | $91M | $-120M | $170M | $68M | $-341M | $62M | $76M | $-27M | $69M | $70M | $-326M | $212M | $-184M | |
| Stock Issued | · | · | $0 | · | · | · | $27.0K | · | · | · | $0 | · | · | · | · | · | |
| Financing Cash Flow | $-412M | $57M | $591M | $81M | $1M | $2M | $-44M | $496M | $3M | $24M | $41M | $-32M | $144M | $492M | $-51M | $2M | |
| Net Change in Cash | $177M | $-199M | $34M | $41M | $33M | $22M | $-93M | $41M | $-55M | $-50M | $47M | $-73M | $116M | $33M | $-39M | $-207M | |
| Taxes Paid | $1M | $-8.0K | $22.0K | $-278.0K | $17.0K | $-400.0K | $-8M | $80.0K | $2M | $13.0K | · | · | · | · | · | · | |
| Free Cash Flow | · | $-815M | · | · | · | $-163M | · | · | · | $-154M | · | · | · | $-144M | · | · | |
| Levered FCF | · | $-820M | · | · | · | $-167M | · | · | · | $-159M | · | · | · | $-146M | · | · |
盈利能力 7
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -38.2% | -47.7% | · | -102.2% | 30.9% | -111.6% | · | -111.1% | -29.3% | -125.1% | · | -99.4% | -47.9% | -87.5% | · | -37.0% | |
| Net Margin | -42.8% | -37.6% | · | -82.1% | 27.3% | -111.6% | · | -105.0% | -29.4% | -119.5% | · | -102.2% | -45.3% | -95.2% | · | -29.4% | |
| Pretax Margin | -42.3% | -37.5% | · | -81.9% | 27.3% | -111.6% | · | -107.7% | -29.4% | -119.4% | · | -97.6% | -41.1% | -86.5% | · | -29.2% | |
| EBITDA Margin | -38.2% | -47.7% | · | -102.2% | 30.9% | -111.6% | · | -111.1% | -29.3% | -125.1% | · | -99.4% | -47.9% | -87.5% | · | -37.0% | |
| ROA | -3.8% | -2.9% | · | -4.2% | 4.3% | -5.3% | · | -4.7% | -2.3% | -5.1% | · | -5.5% | -3.1% | -4.6% | · | -1.9% | |
| ROE | -21.4% | -19.1% | · | -20.1% | 27.6% | -38.0% | · | -28.7% | -19.1% | -36.5% | · | -32.4% | -16.2% | -20.8% | · | -8.3% | |
| ROIC | -23.5% | -23.9% | · | -26.0% | 22.1% | -30.9% | · | -21.9% | -25.1% | -50.4% | · | -47.5% | -23.2% | -25.8% | · | -10.0% |
流动性与偿付能力 3
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 7.9 | 4.1 | · | 2.8 | 2.9 | 9.7 | · | 8.9 | 7.6 | 7.4 | · | 6.4 | 9.1 | 9.8 | · | 7.6 | |
| Quick Ratio | 6.5 | 2.7 | · | 2.5 | 2.6 | 8.6 | · | 8.2 | 6.8 | 6.7 | · | 5.5 | 8.3 | 9.1 | · | 7.0 | |
| Interest Coverage | -22.2 | -22.8 | · | -38.0 | 34.0 | -35.7 | · | -35.7 | -14.7 | -36.0 | · | -34.1 | -39.4 | -71.0 | · | -27.7 |
效率 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.1 | 0.1 | · | 0.1 | 0.2 | 0.0 | · | 0.0 | 0.1 | 0.0 | · | 0.1 | 0.1 | 0.0 | · | 0.1 | |
| Inventory Turnover | 0.1 | 0.3 | · | 0.1 | 0.2 | 0.1 | · | 0.0 | 0.2 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 |
估值 (TTM) 10
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $874M | $1.06B | · | $967M | $944M | $717M | · | $803M | $813M | $777M | · | $615M | $631M | $576M | · | $875M | |
| Net Income TTM | $-565M | $-327M | · | $-256M | $-268M | $-458M | · | $-359M | $-366M | $-385M | · | $-409M | $-309M | $-329M | · | $7M | |
| Market Cap | $13.13B | $12.46B | · | $10.54B | $6.29B | $4.80B | · | $6.32B | $6.96B | $6.32B | · | $6.50B | $5.87B | $5.11B | · | $6.28B | |
| P/E | -22.9 | -36.3 | · | -38.7 | -21.5 | -10.1 | · | -16.4 | -18.9 | -16.2 | · | -15.8 | -18.9 | -15.5 | · | -368.6 | |
| P/S | 15.0 | 11.8 | · | 10.9 | 6.7 | 6.7 | · | 7.9 | 8.6 | 8.1 | · | 10.6 | 9.3 | 8.9 | · | 7.2 | |
| P/B | 29.9 | 25.4 | · | 17.1 | 10.0 | 10.1 | · | 9.5 | 26.4 | 21.3 | · | 20.6 | 13.7 | 10.5 | · | 10.6 | |
| P / Tangible Book | 29.9 | 25.4 | · | 17.1 | 10.0 | 10.1 | · | 9.5 | 26.4 | 21.3 | · | 20.6 | 13.7 | 10.5 | · | 11.1 | |
| P / Cash Flow | · | -15.7 | · | · | · | -31.8 | · | · | · | -42.2 | · | · | · | -38.1 | · | · | |
| P / FCF | · | -15.3 | · | · | · | -29.4 | · | · | · | -40.9 | · | · | · | -35.4 | · | · | |
| Earnings Yield | -4.4% | -2.8% | · | -2.6% | -4.7% | -9.9% | · | -6.1% | -5.3% | -6.2% | · | -6.3% | -5.3% | -6.5% | · | -0.27% |
财务报表 损益表、资产负债表、现金流量表 — 年度，近5年
损益表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 净收入 | $-381M | $-454M | $-366M | $-270M | $-29M |
| 稀释后每股收益 (EPS) | $-2.38 | $-3.04 | $-2.56 | $-1.90 | $-0.20 |
资产负债表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 负债/股东权益比率 | 3.6 | 2.0 | 3.2 | 2.1 | — |
| 流动比率 | 3.8 | 8.5 | 5.9 | 7.1 | 9.7 |
| 速动比率 | 3.4 | 7.4 | 5.2 | 6.4 | 3.6 |
现金流
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 自由现金流 | $-320M | $-546M | $-331M | $-290M | $19M |
我的指标 您的个人关注列表 — 来自完整基本面的选定行
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您的选择已保存，并会跟随您浏览所有股票。
机构持有人 (13F) 575 家申报者 · $10.8B 总计 · 截至 2026年6月30日
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
机构活动 — Q2 2026 与上一季度对比
| 新仓位 | 已退出持仓 | 增加 | 减少 | 净股数变动 |
|---|---|---|---|---|
| 80 (-4 与上一季度对比) | 40 (-25 与上一季度对比) | 199 (+17 与上一季度对比) | 156 (+3 与上一季度对比) | +28.2M |
与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天，外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过，优先显示最近一个已完整报告的季度对。
| 机构 | 价值 | 股份 | % 已追踪的13F | 类型 |
|---|---|---|---|---|
| Capital World Investors | $1718152930 | 21669226 | 15.90% | 股份 |
| FMR LLC | $1062239646 | 13396893 | 9.83% | 股份 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $623182054 | 7859529 | 5.77% | 股份 |
| VANGUARD CAPITAL MANAGEMENT LLC | $571799597 | 7211497 | 5.29% | 股份 |
| WELLINGTON MANAGEMENT GROUP LLP | $558240214 | 7040487 | 5.17% | 股份 |
| TWO SIGMA INVESTMENTS, LP | $495748197 | 6252342 | 4.59% | 股份 |
| STATE STREET CORP | $343710098 | 4334848 | 3.18% | 股份 |
| GEODE CAPITAL MANAGEMENT, LLC | $260920005 | 3157327 | 2.41% | 股份 |
| TWO SIGMA ADVISERS, LP | $241452501 | 3052111 | 2.23% | 股份 |
| Artisan Partners Limited Partnership | $209327536 | 2640024 | 1.94% | 股份 |
| Tweedy, Browne Co LLC | $180805859 | 2280311 | 1.67% | 股份 |
| Deep Track Capital, LP | $174438000 | 2200000 | 1.61% | 股份 |
| BAKER BROS. ADVISORS LP | $162364274 | 2047727 | 1.50% | 股份 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $156967955 | 1979669 | 1.45% | 股份 |
| AMERICAN CENTURY COMPANIES INC | $154383816 | 1947076 | 1.43% | 股份 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $127260529 | 1605001 | 1.18% | 股份 |
| Pictet Asset Management Holding SA | $126981913 | 1596998 | 1.18% | 股份 |
| BARCLAYS PLC | $125150305 | 1578387 | 1.16% | 股份 |
| GOLDMAN SACHS GROUP INC | $117215755 | 1478317 | 1.08% | 股份 |
| Polar Capital Holdings Plc | $115289325 | 1454021 | 1.07% | 股份 |
| Alyeska Investment Group, L.P. | $112426560 | 1417916 | 1.04% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $103108716 | 1300400 | 0.95% | 买入期权 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $103108000 | 1300392 | 0.95% | 股份 |
| VANGUARD FIDUCIARY TRUST CO | $84114400 | 1060845 | 0.78% | 股份 |
| GROUPAMA ASSET MANAGMENT | $75195315 | 937083 | 0.70% | 股份 |
| Capital International Investors | $65316248 | 823764 | 0.60% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $65184309 | 822100 | 0.60% | 卖出期权 |
| Davern Capital Partners, LP | $63329637 | 798709 | 0.59% | 股份 |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | $62422083 | 787263 | 0.58% | 股份 |
| Connor, Clark & Lunn Investment Management Ltd. | $54253072 | 684236 | 0.50% | 股份 |
| Eversept Partners, LP | $52702794 | 664684 | 0.49% | 股份 |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $51970948 | 655454 | 0.48% | 股份 |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $51370722 | 647884 | 0.48% | 股份 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $50113500 | 632028 | 0.46% | 股份 |
| Caption Management, LLC | $49952700 | 630000 | 0.46% | 买入期权 |
| NEUBERGER BERMAN GROUP LLC | $46951653 | 592151 | 0.43% | 股份 |
| EVENTIDE ASSET MANAGEMENT, LLC | $45591750 | 575000 | 0.42% | 股份 |
| PERCEPTIVE ADVISORS LLC | $44878140 | 566000 | 0.42% | 股份 |
| RENAISSANCE TECHNOLOGIES LLC | $44355936 | 559414 | 0.41% | 股份 |
| JANE STREET GROUP, LLC | $44045595 | 555500 | 0.41% | 买入期权 |
| JANE STREET GROUP, LLC | $43070328 | 543200 | 0.40% | 卖出期权 |
| TEACHER RETIREMENT SYSTEM OF TEXAS | $41414514 | 522317 | 0.38% | 股份 |
| BOONE CAPITAL MANAGEMENT LLC | $41228976 | 519977 | 0.38% | 股份 |
| NEW YORK STATE COMMON RETIREMENT FUND | $39648965 | 500050 | 0.37% | 股份 |
| BNP PARIBAS FINANCIAL MARKETS | $36049119 | 454649 | 0.33% | 股份 |
| Candriam S.C.A. | $35251607 | 445019 | 0.33% | 股份 |
| FIRST TRUST ADVISORS LP | $33872360 | 427197 | 0.31% | 股份 |
| PINNACLE ASSOCIATES LTD | $33282136 | 419752 | 0.31% | 股份 |
| BANK OF AMERICA CORP /DE/ | $32643138 | 411693 | 0.30% | 股份 |
| NOMURA HOLDINGS INC | $31889804 | 402192 | 0.30% | 股份 |
| Ikarian Capital, LLC | $31716000 | 400000 | 0.29% | 买入期权 |
| CITADEL ADVISORS LLC | $30645585 | 386500 | 0.28% | 卖出期权 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $28771090 | 362859 | 0.27% | 股份 |
| BlackRock, Inc. | $28184582 | 355462 | 0.26% | 股份 |
| Caption Management, LLC | $27426411 | 345900 | 0.25% | 卖出期权 |
| TD Asset Management Inc | $27002051 | 340548 | 0.25% | 股份 |
| Freestone Grove Partners LP | $26955983 | 339967 | 0.25% | 股份 |
| AXA Investment Managers S.A. | $26590024 | 406451 | 0.25% | 股份 |
| Qube Research & Technologies Ltd | $26479054 | 333952 | 0.25% | 股份 |
| Capital Research Global Investors | $26319205 | 331936 | 0.24% | 股份 |
| CAPITAL FUND MANAGEMENT S.A. | $26130336 | 329554 | 0.24% | 股份 |
| ALLIANCEBERNSTEIN L.P. | $25564391 | 340450 | 0.24% | 股份 |
| Carmignac Gestion | $25452090 | 321000 | 0.24% | 股份 |
| Privium Fund Management B.V. | $25366774 | 319924 | 0.23% | 股份 |
| Swiss National Bank | $24976350 | 315000 | 0.23% | 股份 |
| ARK Investment Management LLC | $23848064 | 300770 | 0.22% | 股份 |
| Integral Health Asset Management, LLC | $23787000 | 300000 | 0.22% | 买入期权 |
| Ikarian Capital, LLC | $23787000 | 300000 | 0.22% | 卖出期权 |
| MILLENNIUM MANAGEMENT LLC | $22904661 | 288872 | 0.21% | 股份 |
| DAVENPORT & Co LLC | $22515188 | 283960 | 0.21% | 股份 |
| Aberdeen Group plc | $21995046 | 277400 | 0.20% | 股份 |
| California Public Employees Retirement System | $21475141 | 270843 | 0.20% | 股份 |
| TimesSquare Capital Management, LLC | $20700361 | 275674 | 0.19% | 股份 |
| MILLENNIUM MANAGEMENT LLC | $20417175 | 257500 | 0.19% | 买入期权 |
| TOCQUEVILLE ASSET MANAGEMENT L.P. | $19918837 | 251215 | 0.18% | 股份 |
| CITADEL ADVISORS LLC | $18709189 | 235959 | 0.17% | 股份 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $18514136 | 233499 | 0.17% | 股份 |
| CITADEL ADVISORS LLC | $18434925 | 232500 | 0.17% | 买入期权 |
| Orion Investment Co | $17470362 | 220335 | 0.16% | 股份 |
| Life Cycle Investment Partners Ltd | $17435554 | 219896 | 0.16% | 股份 |
| ALGERT GLOBAL LLC | $16401374 | 206853 | 0.15% | 股份 |
| Corient Private Wealth LP | $15603561 | 196791 | 0.14% | 股份 |
| Eagle Health Investments LP | $15428010 | 194577 | 0.14% | 股份 |
| SECTOR GAMMA AS | $15022918 | 189468 | 0.14% | 股份 |
| Polymer Capital Management (HK) LTD | $14105453 | 177897 | 0.13% | 股份 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $13252259 | 176485 | 0.12% | 股份 |
| ADAR1 Capital Management, LLC | $13184817 | 166286 | 0.12% | 股份 |
| RHUMBLINE ADVISERS | $13075750 | 164911 | 0.12% | 股份 |
| Sicart Associates LLC | $12741427 | 160694 | 0.12% | 股份 |
| VANGUARD ASSET MANAGEMENT, Ltd | $12296928 | 155088 | 0.11% | 股份 |
| CSS LLC/IL | $12074995 | 152289 | 0.11% | 股份 |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | $11996656 | 151301 | 0.11% | 股份 |
| CITIGROUP INC | $11996577 | 151300 | 0.11% | 买入期权 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $11893500 | 150000 | 0.11% | 股份 |
| Focus Partners Wealth | $11728366 | 147917 | 0.11% | 股份 |
| Hudson Bay Capital Management LP | $11497050 | 145000 | 0.11% | 股份 |
| Artia Global Partners LP | $11447573 | 144376 | 0.11% | 股份 |
| Sonora Investment Management Group, LLC | $11108840 | 169808 | 0.10% | 股份 |
| Fisher Asset Management, LLC | $10877317 | 137184 | 0.10% | 股份 |
| Atle Fund Management AB | $10873116 | 137131 | 0.10% | 股份 |
公司内部人士 48 位内幕人士 · 30 位高管 · 19 位董事
| 内部人士 | 角色 | 上次活动 | 持股数量 | 买入 12个月 | 卖出 12个月 | 净额 12个月 |
|---|---|---|---|---|---|---|
| Brett P Monia | Chief Executive Officer | 2026年6月26日 M | 245571 | 0 | 17 | $-42648430 |
| HOUGEN ELIZABETH L | EVP, Finance & CFO | 2026年3月16日 M | 82660 | 0 | 6 | $-21117075 |
| Kleanthis G Xanthopoulos | President of Regulus | 2007年12月3日 A | — | 0 | 0 | $0 |
| Holly B. Kordasiewicz | EVP, Chief Development Officer | 2026年7月7日 S | 22096 | 0 | 4 | $-4810107 |
| BENNETT C FRANK | EVP, Chief Scientific Officer | 2026年7月7日 J | 0 | 0 | 14 | $-19804154 |
| Eugene Schneider | EVP, Chf Clinical Develop Ofcr | 2026年6月26日 M | 77114 | 0 | 6 | $-4933991 |
| Joseph Baroldi | EVP, Chief Business Officer | 2026年6月26日 M | 4669 | 0 | 17 | $-6405525 |
| O'NEIL PATRICK R. | EVP CLO & General Counsel | 2026年6月26日 S | 61470 | 0 | 16 | $-16034086 |
| Eric Swayze | EVP Research | 2026年6月25日 S | 21759 | 0 | 14 | $-8058784 |
| Brian Birchler | EVP, Corp and Development Ops | 2026年4月15日 M | 67500 | 0 | 6 | $-3556351 |
| Kyle Jenne | EVP, Chf GL Pdt Str Ofcr | 2026年4月15日 M | 23713 | 0 | 4 | $-3334240 |
| Shannon L. Devers | EVP, Chief Human Resources Ofc | 2026年4月2日 S | 16348 | 0 | 15 | $-8854430 |
| Richard S Geary | EVP, Chief Development Officer | 2025年11月6日 M | 59657 | 0 | 13 | $-13858595 |
| Onaiza Cadoret-Manier | EVP,Chf GL Pdt Str & Oper Ofc | 2024年2月2日 S | 35788 | 0 | 0 | $0 |
| Stanley T Crooke | Exec Chairman of the Board | 2021年1月26日 S | 2021 | 0 | 0 | $0 |
| Damien Mcdevitt | Chief Business Officer | 2019年7月15日 M | 2573 | 0 | 0 | $0 |
| Sarah Boyce | Chief Business Officer | 2018年1月15日 M | 8931 | 0 | 0 | $0 |
| ECKER DAVID J | Vice President | 2008年9月2日 M | 0 | 0 | 0 | $0 |
| Michael J Treble | Vice President, Pres of Ibis | 2008年8月11日 M | 0 | 0 | 0 | $0 |
| Jeffrey M Jonas | Executive Vice President | 2008年1月2日 A | — | 0 | 0 | $0 |
| Mark K Wedel | VP & Chief Medical Officer | 2007年7月6日 M | 6603 | 0 | 0 | $0 |
| LEVIN ARTHUR A | Vice President | 2007年4月25日 M | 1674 | 0 | 0 | $0 |
| BROWN RICHARD K | Vice President | 2006年3月8日 M | 2348 | 0 | 0 | $0 |
| MCNEIL JOHN A | Vice President | 2005年1月3日 A | — | 0 | 0 | $0 |
| LOWENSTAM PATRICIA | Vice President | 2005年1月3日 A | 603 | 0 | 0 | $0 |
| STEIN ARON | Vice President | 2004年7月1日 J | 1536 | 0 | 0 | $0 |
| Hans A De Haan | VP, Drug Development | 2004年4月27日 S | 0 | 0 | 0 | $0 |
| LUNDSTEDT KAREN S | Vice President | 2004年3月10日 M | 5407 | 0 | 0 | $0 |
| COLE DOUGLAS L | Vice President | 2004年3月9日 M | 9616 | 0 | 0 | $0 |
| HOLMLUND JON T | Vice President | 2003年7月1日 J | 983 | 0 | 0 | $0 |
| Michael R Hayden | 董事 | 2026年7月31日 P | 24000 | 2 | 0 | $1058700 |
| Peter N Reikes | 董事 | 2026年7月15日 A | 14222 | 0 | 0 | $0 |
| Ludwig Hantson | 董事 | 2026年7月15日 A | — | 0 | 0 | $0 |
| Joan E Herman | 董事 | 2026年7月15日 M | 51306 | 0 | 2 | $-3173720 |
| BERTHELSEN SPENCER R | 董事 | 2026年7月15日 M | 161233 | 0 | 2 | $-1193280 |
| Allene M. Diaz | 董事 | 2026年7月7日 M | 3811 | 0 | 5 | $-5278717 |
| Michael J. Yang | 董事 | 2026年7月1日 A | 7940 | 0 | 0 | $0 |
| Joseph Loscalzo | 董事 | 2026年7月1日 A | 36330 | 0 | 6 | $-8047872 |
| Joseph Klein III | 董事 | 2026年7月1日 A | 11014 | 0 | 14 | $-9356036 |
| Lynne B Parshall | 董事 | 2026年4月15日 S | 51344 | 0 | 6 | $-2171964 |
| Joseph H Wender | 董事 | 2025年12月1日 S | 36035 | 0 | 13 | $-8660283 |
| MUTO FREDERICK T | 董事 | 2022年7月15日 M | 59597 | 0 | 0 | $0 |
| Breaux Castleman | 董事 | 2020年7月1日 A | 19183 | 0 | 0 | $0 |
| REED JOHN C | 董事 | 2012年9月6日 M | 0 | 0 | 0 | $0 |
| Richard D Dimarchi | 董事 | 2010年7月1日 A | — | 0 | 0 | $0 |
| GARIELI CHRISTOPHER | 董事 | 2005年7月1日 A | 155431 | 0 | 0 | $0 |
| SKALETSKY MARK B | 董事 | 2004年7月1日 A | — | 0 | 0 | $0 |
| ISIS PHARMACEUTICALS INC | 10% 所有者 | 2020年10月10日 P | 98322397 | 0 | 0 | $0 |
来自SEC表格3/4/5申报的内部人士；净额=仅公开市场买卖
激进投资者及 5%+ 股东 5 持仓
提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权，意图影响发行人（激进股东持股、董事会活动、并购）。每一行显示该申报人持仓的最新已知状态。
| 申报人 | 已申报 | 持股 | 状态 | 目的 | 申报 |
|---|---|---|---|---|---|
| Ionis Pharmaceuticals, Inc. (“Ionis”) ×8 申报 | 2020年10月13日 | — | 初始申报 | 并购/出售 | SEC |
| Isis Pharmaceuticals, Inc. (“ Isis ”) | 2015年7月31日 | — | 初始申报 | — | SEC |
| Isis Pharmaceuticals, Inc. (“Isis”), Stanley T. Crooke (“Crooke”), B. Lynne Parshall (“Parshall”) ×2 申报 | 2014年11月6日 | — | 初始申报 | — | SEC |
| Genzyme Corporation | 2008年1月15日 | — | 初始申报 | 被动投资 | SEC |
| 未披露的报告人 | 2001年4月12日 | — | 初始申报 | 被动投资 | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF持仓 由 85 只交易所交易基金持有
权重仅反映直接股权持仓（N-PORT）；杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。
| 基金 | 权重 | 单位 | 截至 | 来源 |
|---|---|---|---|---|
| ARKG · ARK ETF Trust | 1.74% | 288230 NS | 2026年4月30日 | N-PORT |
| FXH · First Trust Exchange-Traded Alpha... | 1.72% | 201598 NS | 2026年4月30日 | N-PORT |
| BBP · ETFis Series Trust I | 1.48% | 11708 NS | 2026年4月30日 | N-PORT |
| GDOC · Goldman Sachs ETF Trust | 1.37% | 3614 NS | 2026年5月31日 | N-PORT |
| CGMM · Capital Group Equity ETF Trust I | 1.14% | 414653 NS | 2026年5月31日 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0.94% | 64911 NS | 2026年4月30日 | N-PORT |
| NUSC · Nushares ETF Trust | 0.87% | 150398 NS | 2026年4月30日 | N-PORT |
| TAX · EA Series Trust | 0.87% | 2885 NS | 2026年5月29日 | N-PORT |
| JDOC · J.P. Morgan Exchange-Traded Fund ... | 0.84% | 1257 NS | 2026年4月30日 | N-PORT |
| COPY · RBB Fund Trust | 0.84% | 37653 NS | 2026年5月31日 | N-PORT |
| HRTS · Tema ETF Trust | 0.83% | 5599 NS | 2026年5月31日 | N-PORT |
| IBB · iShares Trust | 0.68% | 1189984 SH | 2026年8月8日 | 每日 |
| FFND · Northern Lights Fund Trust II | 0.67% | 9000 NS | 2026年5月31日 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trus... | 0.64% | 8994 SH | 2026年8月8日 | 每日 |
| BIB · ProShares Trust | 0.63% | 6109 NS | 2026年5月31日 | N-PORT |
| MEDI · Harbor ETF Trust | 0.58% | 2153 NS | 2026年4月30日 | N-PORT |
| FDMO · FIDELITY COVINGTON TRUST | 0.53% | 60169 NS | 2026年4月30日 | N-PORT |
| FNY · First Trust Exchange-Traded Alpha... | 0.53% | 36525 NS | 2026年4月30日 | N-PORT |
| OASC · Unified Series Trust | 0.47% | 5182 NS | 2026年5月31日 | N-PORT |
| QQQJ · Invesco Exchange-Traded Fund Trus... | 0.45% | 94260 SH | 2026年8月8日 | 每日 |
| CGGR · Capital Group Growth ETF | 0.36% | 1150284 NS | 2026年5月31日 | N-PORT |
| VBK · VANGUARD INDEX FUNDS | 0.34% | 2078639 SH | 2026年8月8日 | 每日 |
| SMMV · iShares Trust | 0.32% | 17089 SH | 2026年8月8日 | 每日 |
| BKMC · BNY Mellon ETF Trust | 0.30% | 25160 NS | 2026年4月30日 | N-PORT |
| ISCG · iShares Trust | 0.28% | 51765 SH | 2026年8月8日 | 每日 |
| SCHA · SCHWAB STRATEGIC TRUST | 0.26% | 778644 NS | 2026年5月31日 | N-PORT |
| IWP · iShares Trust | 0.24% | 895755 SH | 2026年8月8日 | 每日 |
| SCHM · SCHWAB STRATEGIC TRUST | 0.23% | 438447 NS | 2026年5月31日 | N-PORT |
| FSMD · FIDELITY COVINGTON TRUST | 0.23% | 71810 NS | 2026年4月30日 | N-PORT |
| BBMC · J.P. Morgan Exchange-Traded Fund ... | 0.22% | 60227 NS | 2026年4月30日 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.22% | 110695 SH | 2026年8月8日 | 每日 |
| JMOM · J.P. Morgan Exchange-Traded Fund ... | 0.21% | 62392 NS | 2026年4月30日 | N-PORT |
| FFLG · FIDELITY COVINGTON TRUST | 0.21% | 16403 NS | 2026年4月30日 | N-PORT |
| FNX · First Trust Exchange-Traded Alpha... | 0.20% | 36263 NS | 2026年4月30日 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0.20% | 50927 SH | 2026年8月8日 | 每日 |
| FHLC · FIDELITY COVINGTON TRUST | 0.19% | 70978 NS | 2026年4月30日 | N-PORT |
| VHT · VANGUARD WORLD FUND | 0.18% | 471609 SH | 2026年8月8日 | 每日 |
| SMLF · iShares Trust | 0.17% | 133297 SH | 2026年8月8日 | 每日 |
| FAD · First Trust Exchange-Traded Alpha... | 0.16% | 10044 NS | 2026年4月30日 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.15% | 1895610 SH | 2026年8月8日 | 每日 |
| VB · VANGUARD INDEX FUNDS | 0.15% | 3600281 SH | 2026年8月8日 | 每日 |
| ESML · iShares Trust | 0.15% | 78764 SH | 2026年8月8日 | 每日 |
| IYH · iShares Trust | 0.15% | 98412 SH | 2026年8月8日 | 每日 |
| NBCR · Neuberger Berman ETF Trust | 0.14% | 16581 NS | 2026年5月31日 | N-PORT |
| ISCB · iShares Trust | 0.14% | 7328 SH | 2026年8月8日 | 每日 |
| AVIE · AMERICAN CENTURY ETF TRUST | 0.13% | 176 NS | 2026年5月31日 | N-PORT |
| SMMD · iShares Trust | 0.12% | 81988 SH | 2026年8月8日 | 每日 |
| WSML · iShares Trust | 0.08% | 9548 SH | 2026年8月8日 | 每日 |
| LRND · New York Life Investments ETF Trust | 0.07% | 2788 NS | 2026年4月30日 | N-PORT |
| EQAL · Invesco Exchange-Traded Fund Trus... | 0.07% | 9928 SH | 2026年8月8日 | 每日 |