| Casdin Capital, LLC |
$73042478 |
88783856 |
27.52% |
股份
|
| VIKING GLOBAL INVESTORS LP |
$48252318 |
58651170 |
18.18% |
股份
|
| MAK CAPITAL ONE LLC |
$23705199 |
28813904 |
8.93% |
股份
|
| VANGUARD GROUP INC |
$22140926 |
17297599 |
8.34% |
股份
|
| Long Focus Capital Management, LLC |
$19333450 |
23500000 |
7.28% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$10084217 |
12252998 |
3.80% |
股份
|
| BlackRock, Inc. |
$6790930 |
8254443 |
2.56% |
股份
|
| Hollow Brook Wealth Management LLC |
$4527632 |
5503381 |
1.71% |
股份
|
| NEUBERGER BERMAN GROUP LLC |
$4039205 |
4958620 |
1.52% |
股份
|
| Qube Research & Technologies Ltd |
$3965795 |
4820463 |
1.49% |
股份
|
| ROYCE & ASSOCIATES LP |
$3722991 |
4525333 |
1.40% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$3207357 |
3896574 |
1.21% |
股份
|
| Tikvah Management LLC |
$2921455 |
3551058 |
1.10% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$2889869 |
3512665 |
1.09% |
股份
|
| MORGAN STANLEY |
$2329614 |
2831668 |
0.88% |
股份
|
| D. E. Shaw & Co., Inc. |
$2318390 |
2818026 |
0.87% |
股份
|
| JANE STREET GROUP, LLC |
$2068513 |
2514299 |
0.78% |
股份
|
| Peapod Lane Capital LLC |
$1983920 |
2411474 |
0.75% |
股份
|
| CITADEL ADVISORS LLC |
$1932169 |
2348570 |
0.73% |
股份
|
| Mink Brook Asset Management LLC |
$1802513 |
2190973 |
0.68% |
股份
|
| Sone Capital Management, LLC |
$1755338 |
2133631 |
0.66% |
股份
|
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
$1638346 |
1991426 |
0.62% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$1555343 |
1889846 |
0.59% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$1447161 |
1759038 |
0.55% |
股份
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$1343561 |
1633112 |
0.51% |
股份
|
| STATE STREET CORP |
$1268997 |
1542478 |
0.48% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$1118065 |
1359018 |
0.42% |
股份
|
| Loews Corp |
$1028375 |
1250000 |
0.39% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$816166 |
992058 |
0.31% |
股份
|
| STALEY CAPITAL ADVISERS INC |
$658160 |
800000 |
0.25% |
股份
|
| NORTHERN TRUST CORP |
$651188 |
791526 |
0.25% |
股份
|
| Man Group plc |
$611096 |
742793 |
0.23% |
股份
|
| Point72 Asset Management, L.P. |
$582464 |
707991 |
0.22% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$555305 |
674733 |
0.21% |
股份
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$477680 |
519783 |
0.18% |
股份
|
| Aster Capital Management (DIFC) Ltd |
$445188 |
541130 |
0.17% |
股份
|
| Jain Global LLC |
$384462 |
467317 |
0.14% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$357295 |
434296 |
0.13% |
股份
|
| Rockefeller Capital Management L.P. |
$352535 |
428510 |
0.13% |
股份
|
| UBS Group AG |
$350578 |
425977 |
0.13% |
股份
|
| Sumitomo Mitsui Trust Group, Inc. |
$339189 |
412288 |
0.13% |
股份
|
| Amova Asset Management Americas, Inc. |
$338076 |
412288 |
0.13% |
股份
|
| Intellectus Partners, LLC |
$332948 |
404702 |
0.13% |
股份
|
| HighTower Advisors, LLC |
$292537 |
355581 |
0.11% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$270301 |
328553 |
0.10% |
股份
|
| OPPENHEIMER & CO INC |
$268694 |
326600 |
0.10% |
股份
|
| Marquette Asset Management, LLC |
$267662 |
325345 |
0.10% |
股份
|
| JOHNSON & JOHNSON |
$256655 |
311967 |
0.10% |
股份
|
| Susquehanna Portfolio Strategies, LLC |
$239828 |
291513 |
0.09% |
股份
|
| XTX Topco Ltd |
$228567 |
277826 |
0.09% |
股份
|
| Squarepoint Ops LLC |
$228196 |
277375 |
0.09% |
股份
|
| HSBC HOLDINGS PLC |
$218766 |
271523 |
0.08% |
股份
|
| Y-Intercept (Hong Kong) Ltd |
$216595 |
263273 |
0.08% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$200637 |
244084 |
0.08% |
股份
|
| Brevan Howard Capital Management LP |
$199357 |
242320 |
0.08% |
股份
|
| QVIDTVM Management LLC |
$182639 |
222000 |
0.07% |
股份
|
| Invesco Ltd. |
$182562 |
221906 |
0.07% |
股份
|
| GOLDMAN SACHS GROUP INC |
$178051 |
216422 |
0.07% |
股份
|
| IEQ CAPITAL, LLC |
$164428 |
199864 |
0.06% |
股份
|
| PRIMECAP MANAGEMENT CO/CA/ |
$126181 |
153374 |
0.05% |
股份
|
| JANUS HENDERSON GROUP PLC |
$121384 |
131610 |
0.05% |
股份
|
| Abich Financial Wealth Management LLC |
$118882 |
91448 |
0.04% |
股份
|
| Vanguard Global Advisers, LLC |
$106433 |
129323 |
0.04% |
股份
|
| Evercore Wealth Management, LLC |
$102837 |
125000 |
0.04% |
股份
|
| Schonfeld Strategic Advisors LLC |
$97604 |
118639 |
0.04% |
股份
|
| Catalyst Funds Management Pty Ltd |
$91151 |
110795 |
0.03% |
股份
|
| AMERIPRISE FINANCIAL INC |
$86223 |
104805 |
0.03% |
股份
|
| MERCER GLOBAL ADVISORS INC /ADV |
$83406 |
101381 |
0.03% |
股份
|
| RHUMBLINE ADVISERS |
$80965 |
98378 |
0.03% |
股份
|
| Mariner, LLC |
$75279 |
91537 |
0.03% |
股份
|
| Bank of New York Mellon Corp |
$74274 |
90282 |
0.03% |
股份
|
| Creative Planning |
$66088 |
80331 |
0.02% |
股份
|
| State of Wyoming |
$61924 |
75269 |
0.02% |
股份
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$58214 |
70760 |
0.02% |
股份
|
| Engineers Gate Manager LP |
$56491 |
68665 |
0.02% |
股份
|
| Hudson Bay Capital Management LP |
$52686 |
64040 |
0.02% |
股份
|
| PRUDENTIAL FINANCIAL INC |
$49626 |
60321 |
0.02% |
股份
|
| CWM, LLC |
$48860 |
53149 |
0.02% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$45920 |
56000 |
0.02% |
卖出期权
|
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO |
$41909 |
51900 |
0.02% |
股份
|
| Cerity Partners LLC |
$41118 |
49980 |
0.02% |
股份
|
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
$38655 |
42090 |
0.01% |
股份
|
| Focus Partners Wealth |
$38309 |
46565 |
0.01% |
股份
|
| BARCLAYS PLC |
$36133 |
43919 |
0.01% |
股份
|
| VICTORY CAPITAL MANAGEMENT INC |
$35709 |
43405 |
0.01% |
股份
|
| Balyasny Asset Management L.P. |
$31703 |
38535 |
0.01% |
股份
|
| NEEDHAM INVESTMENT MANAGEMENT LLC |
$28330 |
34435 |
0.01% |
股份
|
| CIBC WORLD MARKETS CORP |
$25348 |
19803 |
0.01% |
股份
|
| Atom Investors LP |
$24332 |
29576 |
0.01% |
股份
|
| CAPTRUST FINANCIAL ADVISORS |
$23646 |
28742 |
0.01% |
股份
|
| EverSource Wealth Advisors, LLC |
$22880 |
27810 |
0.01% |
股份
|
| ExodusPoint Capital Management, LP |
$22103 |
26867 |
0.01% |
股份
|
| TAKEDA PHARMACEUTICAL CO LTD |
$21470 |
16515 |
0.01% |
股份
|
| Platform Technology Partners |
$20568 |
25000 |
0.01% |
股份
|
| Corient Private Wealth LP |
$20354 |
24740 |
0.01% |
股份
|
| SEI INVESTMENTS CO |
$19760 |
24039 |
0.01% |
股份
|
| CITIGROUP INC |
$19253 |
23402 |
0.01% |
股份
|
| BRIGHTON JONES LLC |
$18054 |
21944 |
0.01% |
股份
|
| WOLVERINE TRADING, LLC |
$18034 |
14200 |
0.01% |
买入期权
|
| Laurion Capital Management LP |
$17952 |
21821 |
0.01% |
股份
|
| Connor, Clark & Lunn Investment Management Ltd. |
$17120 |
20809 |
0.01% |
股份
|
| ROYAL BANK OF CANADA |
$15000 |
18851 |
0.01% |
股份
|
| Jefferies Financial Group Inc. |
$14541 |
17675 |
0.01% |
股份
|
| CITADEL ADVISORS LLC |
$12094 |
14700 |
0.00% |
卖出期权
|
| Merit Financial Group, LLC |
$11966 |
14544 |
0.00% |
股份
|
| ALLSTATE CORP |
$11710 |
14234 |
0.00% |
股份
|
| Tower Research Capital LLC (TRC) |
$11644 |
14153 |
0.00% |
股份
|
| JANE STREET GROUP, LLC |
$11436 |
13900 |
0.00% |
买入期权
|
| CITADEL ADVISORS LLC |
$11271 |
13700 |
0.00% |
买入期权
|
| LPL Financial LLC |
$10327 |
12553 |
0.00% |
股份
|
| Evolution Wealth Advisors, LLC |
$10045 |
12210 |
0.00% |
股份
|
| CIBC Asset Management Inc |
$9923 |
12062 |
0.00% |
股份
|
| Arax Advisory Partners |
$9632 |
11709 |
0.00% |
股份
|
| Ground Swell Capital, LLC |
$9596 |
11664 |
0.00% |
股份
|
| WELLS FARGO & COMPANY/MN |
$8306 |
10095 |
0.00% |
股份
|
| JPMORGAN CHASE & CO |
$5234 |
7003 |
0.00% |
股份
|
| FIFTH THIRD BANCORP |
$5065 |
6156 |
0.00% |
股份
|
| VSM Wealth Advisory, LLC |
$4114 |
5000 |
0.00% |
股份
|
| Global Retirement Partners, LLC |
$3991 |
4851 |
0.00% |
股份
|
| COMERICA BANK |
$3621 |
2829 |
0.00% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$3497 |
4251 |
0.00% |
股份
|
| Allworth Financial LP |
$3471 |
4219 |
0.00% |
股份
|
| FMR LLC |
$2594 |
3153 |
0.00% |
股份
|
| CIBC Private Wealth Group LLC |
$1820 |
1400 |
0.00% |
股份
|
| Atlantic Union Bankshares Corp |
$1646 |
2000 |
0.00% |
股份
|
| Optiver Holding B.V. |
$1631 |
1982 |
0.00% |
股份
|
| IFP Advisors, Inc |
$1126 |
1369 |
0.00% |
股份
|
| Sandy Spring Bank |
$1080 |
1000 |
0.00% |
股份
|
| GSA CAPITAL PARTNERS LLP |
$977 |
1187682 |
0.00% |
股份
|
| Lindbrook Capital, LLC |
$976 |
904 |
0.00% |
股份
|
| Quarry LP |
$940 |
1143 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$933 |
1147 |
0.00% |
股份
|
| IFG Advisory, LLC |
$913 |
1110 |
0.00% |
股份
|
| Essential Partners LLC |
$863 |
1049 |
0.00% |
股份
|
| Steward Partners Investment Advisory, LLC |
$823 |
1000 |
0.00% |
股份
|
| OSAIC HOLDINGS, INC. |
$774 |
943 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$770 |
936 |
0.00% |
股份
|
| Smartleaf Asset Management LLC |
$590 |
789 |
0.00% |
股份
|
| Transamerica Financial Advisors, LLC |
$541 |
658 |
0.00% |
股份
|
| GROUP ONE TRADING LLC |
$309 |
376 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$300 |
365 |
0.00% |
股份
|
| True Wealth Design, LLC |
$292 |
354 |
0.00% |
股份
|
| GAMMA Investing LLC |
$222 |
270 |
0.00% |
股份
|
| Parkside Financial Bank & Trust |
$165 |
200 |
0.00% |
股份
|
| Sunbelt Securities, Inc. |
$155 |
169 |
0.00% |
股份
|
| Russell Investments Group, Ltd. |
$148 |
180 |
0.00% |
股份
|
| Wealth Enhancement Trust Services, Inc. |
$145 |
176 |
0.00% |
股份
|
| SJS Investment Consulting Inc. |
$144 |
174 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$133 |
162 |
0.00% |
股份
|
| Fortitude Family Office, LLC |
$109 |
133 |
0.00% |
股份
|
| PNC Financial Services Group, Inc. |
$105 |
128 |
0.00% |
股份
|
| Virtu Financial LLC |
$80 |
97202 |
0.00% |
股份
|
| SG Americas Securities, LLC |
$47 |
56585 |
0.00% |
股份
|
| ACADIAN ASSET MANAGEMENT LLC |
$43 |
53414 |
0.00% |
股份
|
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO |
$35 |
42591 |
0.00% |
股份
|
| Parallel Advisors, LLC |
$30 |
37 |
0.00% |
股份
|
| SHELL ASSET MANAGEMENT CO |
$17 |
13346 |
0.00% |
股份
|
| Clearstead Advisors, LLC |
$10 |
11 |
0.00% |
股份
|
| JPL Wealth Management, LLC |
$8 |
9 |
0.00% |
股份
|
| NATIONAL BANK OF CANADA /FI/ |
$2 |
2 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$1 |
1 |
0.00% |
股份
|