| BlackRock, Inc. |
$212768666 |
8770349 |
7.57% |
股份
|
| Vestal Point Capital, LP |
$195293000 |
8050000 |
6.95% |
股份
|
| Deep Track Capital, LP |
$187686398 |
7736455 |
6.68% |
股份
|
| Rubric Capital Management LP |
$175345894 |
7227778 |
6.24% |
股份
|
| FMR LLC |
$133071325 |
5485215 |
4.73% |
股份
|
| MORGAN STANLEY |
$115537879 |
4762484 |
4.11% |
股份
|
| STATE STREET CORP |
$113469939 |
4677244 |
4.04% |
股份
|
| BAKER BROS. ADVISORS LP |
$113016569 |
4658556 |
4.02% |
股份
|
| VANGUARD GROUP INC |
$112862243 |
5949512 |
4.01% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$109061534 |
4495529 |
3.88% |
股份
|
| PERCEPTIVE ADVISORS LLC |
$104813438 |
4320422 |
3.73% |
股份
|
| Redmile Group, LLC |
$98830073 |
4073787 |
3.51% |
股份
|
| GENERAL ATLANTIC, L.P. |
$73560808 |
3032185 |
2.62% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$61566526 |
2537291 |
2.19% |
股份
|
| Pictet Asset Management Holding SA |
$57040888 |
2351232 |
2.03% |
股份
|
| ARK Investment Management LLC |
$43502930 |
1793196 |
1.55% |
股份
|
| Capital World Investors |
$43374842 |
1787916 |
1.54% |
股份
|
| Trails Edge Capital Partners, LP |
$38166318 |
1573220 |
1.36% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$35974208 |
1482861 |
1.28% |
股份
|
| CITADEL ADVISORS LLC |
$35832481 |
1477019 |
1.27% |
股份
|
| Soleus Capital Management, L.P. |
$35544854 |
1465163 |
1.26% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$34720069 |
1431317 |
1.23% |
股份
|
| EVENTIDE ASSET MANAGEMENT, LLC |
$31486884 |
1297893 |
1.12% |
股份
|
| BRAIDWELL LP |
$31217016 |
1286769 |
1.11% |
股份
|
| Kynam Capital Management, LP |
$28984805 |
1194757 |
1.03% |
股份
|
| Woodline Partners LP |
$25812786 |
1064006 |
0.92% |
股份
|
| Sumitomo Mitsui Trust Group, Inc. |
$23858788 |
983462 |
0.85% |
股份
|
| Amova Asset Management Americas, Inc. |
$23848954 |
983462 |
0.85% |
股份
|
| Affinity Asset Advisors, LLC |
$23474461 |
967620 |
0.83% |
股份
|
| UBS Group AG |
$22249259 |
917117 |
0.79% |
股份
|
| NORTHERN TRUST CORP |
$21253458 |
876070 |
0.76% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$20429079 |
842089 |
0.73% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$20215761 |
833296 |
0.72% |
股份
|
| Nuveen, LLC |
$20034709 |
825833 |
0.71% |
股份
|
| GOLDMAN SACHS GROUP INC |
$19737670 |
813589 |
0.70% |
股份
|
| KENNEDY CAPITAL MANAGEMENT LLC |
$17576564 |
724508 |
0.63% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$16650560 |
686338 |
0.59% |
股份
|
| Rhenman & Partners Asset Management AB |
$16599905 |
684250 |
0.59% |
股份
|
| RAYMOND JAMES FINANCIAL INC |
$14392512 |
593262 |
0.51% |
股份
|
| Sofinnova Investments, Inc. |
$12714617 |
524098 |
0.45% |
股份
|
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
$11575441 |
477141 |
0.41% |
股份
|
| Elmind Capital, LP |
$11159600 |
460000 |
0.40% |
股份
|
| CITIGROUP INC |
$9446456 |
389384 |
0.34% |
股份
|
| Candriam S.C.A. |
$9159082 |
377902 |
0.33% |
股份
|
| Fisher Asset Management, LLC |
$8963219 |
369465 |
0.32% |
股份
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$8821009 |
363603 |
0.31% |
股份
|
| FIRST TRUST ADVISORS LP |
$8754172 |
360848 |
0.31% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$8262422 |
340578 |
0.29% |
股份
|
| WELLINGTON MANAGEMENT GROUP LLP |
$8106188 |
334138 |
0.29% |
股份
|
| ArrowMark Colorado Holdings LLC |
$7636126 |
314762 |
0.27% |
股份
|
| ADAR1 Capital Management, LLC |
$7599105 |
313236 |
0.27% |
股份
|
| Bank of New York Mellon Corp |
$6614239 |
272640 |
0.24% |
股份
|
| EcoR1 Capital, LLC |
$6550200 |
270000 |
0.23% |
股份
|
| Foresite Capital Management V, LLC |
$6428900 |
265000 |
0.23% |
股份
|
| Susquehanna Portfolio Strategies, LLC |
$5650736 |
232924 |
0.20% |
股份
|
| WestHill Financial Advisors, Inc. |
$5296759 |
218333 |
0.19% |
股份
|
| HighVista Strategies LLC |
$4942709 |
203739 |
0.18% |
股份
|
| Y-Intercept (Hong Kong) Ltd |
$4668449 |
192434 |
0.17% |
股份
|
| TD Asset Management Inc |
$4617745 |
190344 |
0.16% |
股份
|
| Russell Investments Group, Ltd. |
$4500823 |
185524 |
0.16% |
股份
|
| Abu Dhabi Investment Council Co P.J.S.C |
$4495645 |
185311 |
0.16% |
股份
|
| D. E. Shaw & Co., Inc. |
$4477207 |
184551 |
0.16% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$4353798 |
179464 |
0.15% |
股份
|
| Invesco Ltd. |
$4319469 |
178049 |
0.15% |
股份
|
| Jump Financial, LLC |
$4143317 |
170788 |
0.15% |
股份
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$4096471 |
168857 |
0.15% |
股份
|
| DEUTSCHE BANK AG\ |
$3674250 |
151453 |
0.13% |
股份
|
| PRUDENTIAL FINANCIAL INC |
$3521824 |
145170 |
0.13% |
股份
|
| Alyeska Investment Group, L.P. |
$3350840 |
138122 |
0.12% |
股份
|
| Cubist Systematic Strategies, LLC |
$3030273 |
327952 |
0.11% |
股份
|
| Swiss National Bank |
$3020370 |
124500 |
0.11% |
股份
|
| RHUMBLINE ADVISERS |
$2985716 |
123072 |
0.11% |
股份
|
| DIADEMA PARTNERS LP |
$2948536 |
121539 |
0.10% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$2906348 |
119800 |
0.10% |
买入期权
|
| Burkehill Global Management, LP |
$2886261 |
118972 |
0.10% |
股份
|
| Qube Research & Technologies Ltd |
$2638445 |
108757 |
0.09% |
股份
|
| SEI INVESTMENTS CO |
$2608193 |
107510 |
0.09% |
股份
|
| WELLS FARGO & COMPANY/MN |
$2512681 |
103573 |
0.09% |
股份
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$2438926 |
157350 |
0.09% |
股份
|
| Boxer Capital Management, LLC |
$2426000 |
100000 |
0.09% |
股份
|
| Phocas Financial Corp. |
$2416029 |
99589 |
0.09% |
股份
|
| Zurcher Kantonalbank (Zurich Cantonalbank) |
$2366975 |
97567 |
0.08% |
股份
|
| Jasper Ridge Partners, L.P. |
$2321949 |
95711 |
0.08% |
股份
|
| EDMOND DE ROTHSCHILD HOLDING S.A. |
$2183400 |
90000 |
0.08% |
股份
|
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd |
$2180610 |
89885 |
0.08% |
股份
|
| XTX Topco Ltd |
$2123648 |
87537 |
0.08% |
股份
|
| Man Group plc |
$2076244 |
85583 |
0.07% |
股份
|
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group |
$2062100 |
85000 |
0.07% |
股份
|
| FLAX POND CAPITAL, LLC |
$1933522 |
79700 |
0.07% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$1875924 |
77460 |
0.07% |
股份
|
| Point72 Asset Management, L.P. |
$1772654 |
73069 |
0.06% |
股份
|
| Legal & General Group Plc |
$1747351 |
72026 |
0.06% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$1724995 |
111290 |
0.06% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$1681873 |
69327 |
0.06% |
股份
|
| Rafferty Asset Management, LLC |
$1658414 |
68360 |
0.06% |
股份
|
| Swedbank AB |
$1576900 |
65000 |
0.06% |
股份
|
| Jain Global LLC |
$1568676 |
64661 |
0.06% |
股份
|
| WESBANCO BANK INC |
$1521102 |
62700 |
0.05% |
股份
|
| TEMA ETFS LLC |
$1453576 |
76625 |
0.05% |
股份
|
| Polymer Capital Management (HK) LTD |
$1428865 |
58898 |
0.05% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$1402228 |
57800 |
0.05% |
卖出期权
|
| MetLife Investment Management, LLC |
$1378162 |
56808 |
0.05% |
股份
|
| JANE STREET GROUP, LLC |
$1234834 |
50900 |
0.04% |
买入期权
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$1207663 |
49780 |
0.04% |
股份
|
| Verdad Advisers, LP |
$1201137 |
49511 |
0.04% |
股份
|
| JPMORGAN CHASE & CO |
$1161304 |
48692 |
0.04% |
股份
|
| Mariner, LLC |
$1084810 |
44716 |
0.04% |
股份
|
| VANGUARD ASSET MANAGEMENT, Ltd |
$1071637 |
44173 |
0.04% |
股份
|
| CITADEL ADVISORS LLC |
$994660 |
41000 |
0.04% |
买入期权
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$923821 |
38080 |
0.03% |
股份
|
| Vanguard Global Advisers, LLC |
$898469 |
37035 |
0.03% |
股份
|
| PROFUND ADVISORS LLC |
$854777 |
35234 |
0.03% |
股份
|
| Quantinno Capital Management LP |
$800531 |
32998 |
0.03% |
股份
|
| Penn Capital Management Company, LLC |
$800168 |
32983 |
0.03% |
股份
|
| STATE OF WISCONSIN INVESTMENT BOARD |
$787019 |
32441 |
0.03% |
股份
|
| Persistent Asset Partners Ltd |
$751405 |
30973 |
0.03% |
股份
|
| Verition Fund Management LLC |
$737625 |
30405 |
0.03% |
股份
|
| Balyasny Asset Management L.P. |
$656621 |
27066 |
0.02% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$648446 |
26729 |
0.02% |
股份
|
| AlphaCentric Advisors LLC |
$627000 |
25845 |
0.02% |
股份
|
| JANUS HENDERSON GROUP PLC |
$610109 |
39400 |
0.02% |
股份
|
| Creative Planning |
$608198 |
25070 |
0.02% |
股份
|
| PSP Research LLC |
$606500 |
25000 |
0.02% |
股份
|
| Aquatic Capital Management LLC |
$578916 |
23863 |
0.02% |
股份
|
| COOKSON PEIRCE & CO INC |
$557980 |
23000 |
0.02% |
股份
|
| BARCLAYS PLC |
$545413 |
22482 |
0.02% |
股份
|
| AXQ CAPITAL, LP |
$517563 |
21334 |
0.02% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$507277 |
20910 |
0.02% |
股份
|
| SummitTX Capital, L.P. |
$496942 |
20484 |
0.02% |
股份
|
| VICTORY CAPITAL MANAGEMENT INC |
$493691 |
20350 |
0.02% |
股份
|
| State of New Jersey Common Pension Fund D |
$486680 |
20061 |
0.02% |
股份
|
| Virtus Investment Advisers, LLC |
$468315 |
19304 |
0.02% |
股份
|
| INTECH INVESTMENT MANAGEMENT LLC |
$450241 |
18559 |
0.02% |
股份
|
| VOYA INVESTMENT MANAGEMENT LLC |
$449635 |
18534 |
0.02% |
股份
|
| Vanguard Investments Australia, Ltd. |
$436219 |
17981 |
0.02% |
股份
|
| Trexquant Investment LP |
$428068 |
17645 |
0.02% |
股份
|
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM |
$427243 |
17611 |
0.02% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$420547 |
17335 |
0.01% |
股份
|
| RAM Investment Partners, LLC |
$419310 |
17284 |
0.01% |
股份
|
| Cerity Partners LLC |
$418583 |
17254 |
0.01% |
股份
|
| ARIZONA STATE RETIREMENT SYSTEM |
$415331 |
17120 |
0.01% |
股份
|
| China Universal Asset Management Co., Ltd. |
$399247 |
16457 |
0.01% |
股份
|
| KLP KAPITALFORVALTNING AS |
$393012 |
16200 |
0.01% |
股份
|
| Velan Capital Investment Management LP |
$388160 |
16000 |
0.01% |
股份
|
| ProShare Advisors LLC |
$386729 |
15941 |
0.01% |
股份
|
| AlphaQuest LLC |
$381999 |
20137 |
0.01% |
股份
|
| Walleye Capital LLC |
$377680 |
15568 |
0.01% |
股份
|
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC |
$341460 |
14075 |
0.01% |
股份
|
| Marex Group Ltd |
$339640 |
14000 |
0.01% |
股份
|
| Allspring Global Investments Holdings, LLC |
$335855 |
13844 |
0.01% |
股份
|
| MERCER GLOBAL ADVISORS INC /ADV |
$291969 |
12035 |
0.01% |
股份
|
| CITADEL ADVISORS LLC |
$276564 |
11400 |
0.01% |
卖出期权
|
| CLEAR WAVE WEALTH MANAGEMENT LLC |
$261824 |
10792 |
0.01% |
股份
|
| OSAIC HOLDINGS, INC. |
$254730 |
10500 |
0.01% |
股份
|
| IEQ CAPITAL, LLC |
$251576 |
10370 |
0.01% |
股份
|
| ROYAL BANK OF CANADA |
$236000 |
9733 |
0.01% |
股份
|
| E Fund Management Co., Ltd. |
$233842 |
9639 |
0.01% |
股份
|
| XPONANCE LLC |
$230421 |
9498 |
0.01% |
股份
|
| M&T Bank Corp |
$226297 |
9328 |
0.01% |
股份
|
| EP Wealth Advisors, LLC |
$213876 |
8816 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$211111 |
8702 |
0.01% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$131892 |
5436587 |
0.00% |
股份
|
| Rockefeller Capital Management L.P. |
$129015 |
5318 |
0.00% |
股份
|
| Mirae Asset Global Investments Co., Ltd. |
$112203 |
4625 |
0.00% |
股份
|
| State of Wyoming |
$111717 |
4605 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$91897 |
3788 |
0.00% |
股份
|
| Global Retirement Partners, LLC |
$81683 |
3367 |
0.00% |
股份
|
| Avalon Trust Co |
$64289 |
2650 |
0.00% |
股份
|
| GF FUND MANAGEMENT CO. LTD. |
$52887 |
2180 |
0.00% |
股份
|
| Federation des caisses Desjardins du Quebec |
$50703 |
2090 |
0.00% |
股份
|
| Tower Research Capital LLC (TRC) |
$46967 |
1936 |
0.00% |
股份
|
| Intesa Sanpaolo Wealth Management |
$39058 |
1610 |
0.00% |
股份
|
| Smartleaf Asset Management LLC |
$26998 |
1132 |
0.00% |
股份
|
| Kemnay Advisory Services Inc. |
$22610 |
932 |
0.00% |
股份
|
| Allworth Financial LP |
$21325 |
879 |
0.00% |
股份
|
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. |
$19165 |
790 |
0.00% |
股份
|
| Accent Capital Management, LLC |
$18146 |
748 |
0.00% |
股份
|
| Arax Advisory Partners |
$17516 |
722 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$17055 |
703 |
0.00% |
股份
|
| SIGNATUREFD, LLC |
$15890 |
655 |
0.00% |
股份
|
| GAMMA Investing LLC |
$15769 |
650 |
0.00% |
股份
|
| PNC Financial Services Group, Inc. |
$14556 |
600 |
0.00% |
股份
|
| Optiver Holding B.V. |
$13828 |
570 |
0.00% |
股份
|
| CWM, LLC |
$13036 |
841 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$11356 |
469 |
0.00% |
股份
|
| Larson Financial Group LLC |
$10699 |
441 |
0.00% |
股份
|
| Steward Partners Investment Advisory, LLC |
$10626 |
438 |
0.00% |
股份
|
| US BANCORP \DE\ |
$10019 |
413 |
0.00% |
股份
|
| LOS ANGELES CAPITAL MANAGEMENT LLC |
$9558 |
394 |
0.00% |
股份
|
| Handelsbanken Fonder AB |
$8478 |
547000 |
0.00% |
股份
|
| BESSEMER GROUP INC |
$7424 |
306003 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$6866 |
283 |
0.00% |
股份
|
| GROUP ONE TRADING LLC |
$6599 |
272 |
0.00% |
股份
|
| IFP Advisors, Inc |
$5434 |
224 |
0.00% |
股份
|
| FIFTH THIRD BANCORP |
$5294 |
218 |
0.00% |
股份
|
| Essential Partners LLC |
$4609 |
190 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$4076 |
168 |
0.00% |
股份
|
| Point72 (DIFC) Ltd |
$2485 |
269 |
0.00% |
股份
|
| SJS Investment Consulting Inc. |
$2232 |
92 |
0.00% |
股份
|
| MassMutual Private Wealth & Trust, FSB |
$1747 |
72 |
0.00% |
股份
|
| Clearstead Advisors, LLC |
$1651 |
68 |
0.00% |
股份
|
| Ameritas Advisory Services, LLC |
$1650 |
68 |
0.00% |
股份
|
| Versant Capital Management, Inc |
$1446 |
61 |
0.00% |
股份
|
| Parkside Financial Bank & Trust |
$1383 |
57 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$1067 |
44 |
0.00% |
股份
|
| COMERICA BANK |
$1024 |
54 |
0.00% |
股份
|
| Torren Management, LLC |
$915 |
59 |
0.00% |
股份
|
| True Wealth Design, LLC |
$874 |
36 |
0.00% |
股份
|
| SG Americas Securities, LLC |
$841 |
34655 |
0.00% |
股份
|
| JONES FINANCIAL COMPANIES LLLP |
$802 |
35 |
0.00% |
股份
|
| Bare Financial Services, Inc |
$776 |
32 |
0.00% |
股份
|
| Fortitude Family Office, LLC |
$752 |
31 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$631 |
26 |
0.00% |
股份
|
| CANADA LIFE ASSURANCE Co |
$199 |
8226 |
0.00% |
股份
|
| Quarry LP |
$121 |
5 |
0.00% |
股份
|
| Stone House Investment Management, LLC |
$97 |
4 |
0.00% |
股份
|
| Silver Grove Financial Group, Inc. |
$97 |
4 |
0.00% |
股份
|
| Hughes Financial Services, LLC |
$73 |
3 |
0.00% |
股份
|
| KBC Group NV |
$53 |
2192 |
0.00% |
股份
|
| Pacer Advisors, Inc. |
$28 |
1142 |
0.00% |
股份
|
| CIBC Private Wealth Group LLC |
$9 |
1 |
0.00% |
股份
|
| Avion Wealth |
$6 |
250 |
0.00% |
股份
|
| Covestor Ltd |
$1 |
31 |
0.00% |
股份
|