PTGX Protagonist Therapeutics, Inc. - Common Stock
$150.70
价格 · 八月 24, 2026
截至...的财报数据 八月 5, 2026
52周区间
$54–$161
90% of range
分析师评级
BUY
20 analysts
目标价
$170
+13% upside
P/E (TTM)
-75.4
ROE
-20.3%
净利润率
-282.8%
PTGX 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围
价格
$150.70
市值
$9.68B
P/E (TTM)
-75.4
每股收益 (TTM)
$-2.05
营收 (TTM)
$46M
股息收益率
—
ROE
-20.3%
负债/权益
—
52周区间
$55 – $161
PTGX 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图
Configure
10年表现 收入、净利润、利润率和每股收益趋势
营收与净利润
$46M
2017-12-31
→
2025-12-31
EPS
$-2.05
2020-12-31
→
2025-12-31
自由现金流
$56M
2016-12-31
→
2025-12-31
利润率
-282.8%
估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜？
指标
5年趋势
PTGX
同行中位数
P/E (TTM)
-75.4
115.3
P/S (TTM) (市销率 (TTM))
210.3
33.9
P/B (市净率)
15.7
3.9
Price / FCF (股价/自由现金流)
172.6
—
盈利能力 毛利率、营业利润率和净利率；股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)
指标
5年趋势
PTGX
同行中位数
Operating Margin (营业利润率)
-343.6%
—
Net Profit Margin (净利润率)
-282.8%
-93.3%
ROA
-18.4%
-22.2%
ROE
-20.3%
-37.6%
ROIC
-25.9%
—
财务健康 债务、流动性、偿付能力 — 资产负债表强度
指标
5年趋势
PTGX
同行中位数
Current Ratio (流动比率)
12.7
5.7
Quick Ratio (速动比率)
12.5
—
成长 营收、每股收益 (EPS) 和净利润增长：同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)
指标
5年趋势
PTGX
同行中位数
Revenue YoY (营收同比增长)
-89.4%
—
Revenue CAGR 3Y (营收3年复合年增长率)
20.1%
—
Revenue CAGR 5Y (营收5年复合年增长率)
10.0%
—
资本效率 资产周转率、库存周转率、应收账款周转率
指标
5年趋势
PTGX
同行中位数
PTGX 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间
买入
20 位分析师
- 强烈买入 7 35.0%
- 买入 11 55.0%
- 持有 2 10.0%
- 卖出 0 0.0%
- 强烈卖出 0 0.0%
12个月价格目标
13 位分析师 · 2026-08-23
中位数
$169.00
现在
$150.70
最低
$149.00
最高
$225.00
中位数目标
$169.00
+12.1%
平均目标
$170.38
+13.1%
收益历史 每股收益实际值 vs 预估值，惊喜%，达标率，下次财报日期
平均惊喜
0.11%
| 期间 | EPS Actual | EPS 预期 | 惊喜 |
|---|---|---|---|
| 2026年6月30日 | $2.29 | $2.12 | 0.17% |
| 2026年3月31日 | $0.05 | $-0.54 | 0.59% |
| 2025年12月31日 | $-0.69 | $-0.50 | -0.19% |
| 2025年9月30日 | $-0.62 | $-0.65 | 0.03% |
| 2025年6月30日 | $-0.55 | $-0.59 | 0.04% |
| 2025年3月31日 | $-0.19 | $-0.24 | 0.05% |
同行比较（GICS 子行业） 关键指标与行业同行对比
| 股票代码 | 市值 | P/E | 营收同比增长 | 净利润率 | ROE | 毛利率 |
|---|---|---|---|---|---|---|
| PTGX | $5.47B | -42.6 | -89.4% | -282.8% | -20.3% | — |
| PRAX | $7.43B | -21.9 | 249.5% | — | -47.3% | — |
| APGE | $5.16B | -17.9 | — | — | — | — |
| SMMT | $13.56B | -12.1 | — | — | -235.1% | — |
| KRYS | $7.20B | 36.0 | 33.9% | 52.6% | 18.1% | — |
| IONS | $12.92B | -33.2 | — | — | -68.1% | — |
| KYMR | $6.33B | -21.1 | -16.7% | -794.0% | -24.4% | — |
| SYRE | $2.56B | 10.1 | -62.0% | — | -26.5% | — |
| PCVX | $6.05B | -8.2 | — | — | -26.6% | — |
| TWST | $1.71B | -21.6 | 20.3% | -20.6% | -17.0% | — |
| IMVT | $5.07B | -9.0 | 229.2% | — | -73.7% | — |
完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表
损益表 16
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $46M | $434M | $60M | $27M | $27M | $29M | $231.0K | $31M | $20M | |
| R&D Expense | $159M | $138M | $120M | $126M | $126M | $75M | $65M | $59M | $46M | |
| SG&A Expense | $45M | $43M | $33M | $32M | $27M | $19M | $16M | $14M | $12M | |
| Operating Expenses | $204M | $182M | $154M | $158M | $153M | $93M | $81M | $73M | $58M | |
| Operating Income | $-158M | $253M | $-94M | $-131M | $-126M | $-65M | $-81M | $-42M | $-38M | |
| Interest Expense | · | · | · | · | · | $598.0K | $169.0K | · | · | |
| Interest Income | $29M | $26M | $15M | $4M | $443.0K | $900.0K | $3M | $3M | $948.0K | |
| Other Non-op | $27.0K | $250.0K | $-201.0K | $-80.0K | $-149.0K | $-46.0K | $-1.0K | $-20.0K | $-8.0K | |
| Pretax Income | $-129M | $279M | $-79M | $-127M | $-126M | $-65M | $-78M | $-40M | $-37M | |
| Income Tax | $838.0K | $4M | $0 | $0 | $0 | $1M | $-691.0K | $-799.0K | $0 | |
| Net Income | $-130M | $275M | $-79M | $-127M | $-126M | $-66M | $-77M | $-39M | $-37M | |
| EPS (Basic) | $-2.05 | $4.47 | $-1.39 | $-2.60 | $-2.71 | $-1.92 | · | · | · | |
| EPS (Diluted) | $-2.05 | $4.23 | $-1.39 | $-2.60 | $-2.71 | $-1.92 | · | · | · | |
| Shares (Basic) | 63,573,048 | 61,566,989 | 56,763,559 | 49,042,232 | 46,322,910 | 34,396,446 | · | · | · | |
| Shares (Diluted) | 63,573,048 | 65,077,722 | 56,763,559 | 49,042,232 | 46,322,910 | 34,396,446 | · | · | · | |
| EBITDA | $-157M | $254M | $-93M | $-130M | $-125M | $-64M | $-80M | $-42M | $-37M |
资产负债表 22
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $128M | $97M | $187M | $126M | $124M | $117M | $33M | $82M | $106M | |
| Short-term Investments | $439M | $322M | $155M | $112M | $203M | $188M | $100M | $47M | $38M | |
| Prepaid Expense | $10M | $8M | $4M | $6M | $9M | $6M | $6M | $3M | $4M | |
| Other Current Assets | $10.0K | $248.0K | $76.0K | $42.0K | · | · | · | · | $1M | |
| Current Assets | $578M | $592M | $356M | $243M | $341M | $316M | $145M | $138M | $151M | |
| PP&E (Net) | $4M | $3M | $1M | $2M | $2M | $1M | $2M | $861.0K | $879.0K | |
| PP&E (Gross) | $12M | $10M | $7M | $7M | $6M | $5M | $4M | $3M | $2M | |
| Accum. Depreciation | $8M | $7M | $6M | $5M | $4M | $3M | $3M | $2M | $2M | |
| Total Assets | $668M | $745M | $358M | $248M | $348M | $324M | $155M | $139M | $164M | |
| Accounts Payable | $5M | $2M | $772.0K | $4M | $2M | $3M | $3M | $6M | $1M | |
| Accrued Liabilities | $28M | $24M | $19M | $25M | $38M | $18M | $12M | $11M | $10M | |
| Current Liabilities | $45M | $47M | $21M | $31M | $44M | $40M | $35M | $26M | $43M | |
| Capital Leases | $8M | $10M | · | $1M | $4M | $4M | $6M | · | · | |
| Other Non-current Liabilities | · | · | · | · | · | $121.0K | · | · | · | |
| Total Liabilities | $53M | $69M | $21M | $32M | $48M | $45M | $75M | $27M | $43M | |
| Long-term Debt | · | · | · | · | · | · | $10M | · | · | |
| Common Stock | $1.0K | $1.0K | $1.0K | · | · | · | · | · | $0 | |
| Retained Earnings | $-471M | $-341M | $-616M | $-537M | $-409M | $-284M | $-218M | $-140M | $-102M | |
| AOCI | $641.0K | $-82.0K | $-105.0K | $-359.0K | $-299.0K | $28.0K | $-221.0K | $-233.0K | $-6.0K | |
| Stockholders' Equity | $615M | $675M | $337M | $216M | $300M | $280M | $80M | $113M | $121M | |
| Liabilities + Equity | $668M | $745M | $358M | $248M | $348M | $324M | $155M | $139M | $164M | |
| Shares Outstanding | 62,577,897 | 61,035,139 | 57,708,613 | 49,339,252 | 47,838,330 | 43,745,465 | 27,217,649 | 23,187,219 | 21,088,306 |
现金流 16
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $1M | $826.0K | $977.0K | $1M | $813.0K | $948.0K | $732.0K | $527.0K | $406.0K | |
| Stock-based Comp | $46M | $38M | $29M | $24M | $16M | $8M | $8M | $7M | $4M | |
| Deferred Tax | · | · | · | · | · | $1M | $-775.0K | $-799.0K | · | |
| Other Non-cash | $141M | $-129M | $-22M | $-6M | $478.0K | $-16M | $27M | $-18M | $36M | |
| Operating Cash Flow | $58M | $184M | $-70M | $-108M | $-108M | $-72M | $-42M | $-50M | $4M | |
| CapEx | $2M | $1M | $609.0K | $795.0K | $1M | $471.0K | $967.0K | $486.0K | $666.0K | |
| Investing Cash Flow | $-49M | $-299M | $-39M | $91M | $-16M | $-91M | $-54M | $2M | $16M | |
| Debt Issued | · | · | · | · | · | · | $10M | · | · | |
| Net Debt Issued | · | · | · | · | · | $-11M | · | · | · | |
| Stock Issued | · | · | $108M | · | $124M | $213M | $34M | $2M | · | |
| Net Stock Activity | · | · | $108M | · | $124M | $213M | $34M | $2M | · | |
| Financing Cash Flow | $23M | $26M | $170M | $19M | $130M | $248M | $46M | $24M | $66M | |
| Net Change in Cash | $31M | $-89M | $61M | $2M | $6M | $84M | $-49M | $-24M | $85M | |
| Taxes Paid | $4M | $2M | · | · | · | · | · | · | · | |
| Free Cash Flow | $56M | $183M | $-71M | $-109M | $-109M | $-73M | $-42M | $-50M | $3M | |
| Levered FCF | · | · | · | · | · | $-74M | $-43M | · | · |
盈利能力 7
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -343.6% | 58.2% | -156.1% | -494.2% | -460.0% | · | · | -136.7% | · | |
| Net Margin | -282.8% | 63.3% | -131.6% | -479.3% | -458.9% | · | · | -125.9% | · | |
| Pretax Margin | -281.0% | 64.3% | -131.6% | -479.3% | -458.9% | · | · | -128.4% | · | |
| EBITDA Margin | -340.9% | 58.4% | -154.5% | -490.4% | -457.0% | · | · | -135.0% | · | |
| ROA | -18.4% | 49.9% | -26.1% | -42.8% | -37.4% | -27.6% | -52.4% | -25.7% | -28.7% | |
| ROE | -20.3% | 45.6% | -24.7% | -55.5% | -39.9% | -29.4% | -88.0% | -32.9% | -35.5% | |
| ROIC | -25.9% | 36.9% | -27.8% | -60.9% | -41.9% | -23.5% | -99.8% | -38.3% | -31.4% |
流动性与偿付能力 3
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 12.7 | 12.5 | 16.7 | 7.8 | 7.7 | 7.8 | 4.1 | 5.3 | 3.5 | |
| Quick Ratio | 12.5 | 8.8 | 16.1 | 7.6 | 7.4 | 7.6 | 3.8 | 4.9 | 3.4 | |
| Interest Coverage | · | · | · | · | · | -107.9 | -476.5 | · | · |
效率 1
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.1 | 0.8 | 0.2 | 0.1 | 0.1 | · | · | 0.2 | · |
增长率 3
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | -89.4% | 624.1% | 125.7% | -2.8% | -4.4% | · | · | · | · | |
| Revenue CAGR 3Y | 20.1% | 151.3% | 28.0% | · | · | · | · | · | · | |
| Revenue CAGR 5Y | 10.0% | · | · | · | · | · | · | · | · |
估值 (TTM) 10
| 指标 | 趋势 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $46M | $434M | $60M | $27M | $27M | $29M | $231.0K | $31M | $20M | |
| Net Income TTM | $-130M | $275M | $-79M | $-127M | $-126M | $-66M | $-77M | $-39M | $-37M | |
| Market Cap | $5.47B | $2.36B | $1.32B | $538M | $1.64B | $882M | $192M | $156M | $439M | |
| P/E | -42.6 | 9.1 | -16.5 | -4.2 | -12.6 | -10.5 | · | · | · | |
| P/S | 118.8 | 5.4 | 22.1 | 20.3 | 59.8 | 30.8 | 830.7 | 5.0 | 21.9 | |
| P/B | 8.9 | 3.5 | 3.9 | 2.5 | 5.5 | 3.2 | 2.4 | 1.4 | 3.6 | |
| P / Tangible Book | 8.9 | 3.5 | 3.9 | 2.5 | 5.5 | 3.2 | · | · | · | |
| P / Cash Flow | 94.8 | 12.8 | -18.8 | -5.0 | -15.2 | -12.2 | -4.6 | -3.1 | 113.3 | |
| P / FCF | 97.5 | 12.9 | -18.7 | -4.9 | -15.0 | -12.1 | -4.5 | -3.1 | 136.8 | |
| Earnings Yield | -2.4% | 11.0% | -6.1% | -23.8% | -7.9% | -9.5% | · | · | · |
损益表 15
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $213M | $56M | $7M | $5M | $6M | $28M | $171M | $5M | $4M | $255M | $60M | $0 | $0 | $0 | $0 | $0 | |
| R&D Expense | $42M | $47M | $46M | $40M | $37M | $36M | $35M | $36M | $34M | $34M | $29M | $31M | $33M | $27M | $30M | $25M | |
| SG&A Expense | $13M | $13M | $11M | $11M | $11M | $12M | $9M | $10M | $9M | $15M | $8M | $8M | $9M | $9M | $7M | $7M | |
| Operating Expenses | $55M | $60M | $58M | $51M | $48M | $48M | $44M | $46M | $43M | $49M | $37M | $38M | $42M | $36M | $37M | $32M | |
| Operating Income | $159M | $-4M | $-50M | $-46M | $-42M | $-19M | $127M | $-41M | $-39M | $206M | $23M | $-38M | $-42M | $-36M | $-37M | $-32M | |
| Interest Income | $6M | $6M | $7M | $7M | $7M | $8M | $7M | $8M | $7M | $4M | $4M | $4M | $4M | $2M | $2M | $1M | |
| Other Non-op | $-81.0K | $53.0K | $-124.0K | $33.0K | $36.0K | $82.0K | $31.0K | $141.0K | $97.0K | $-19.0K | $44.0K | $-31.0K | $-19.0K | $-195.0K | $71.0K | $-86.0K | |
| Pretax Income | $165M | $2M | $-44M | $-39M | $-35M | $-12M | $134M | $-34M | $-31M | $211M | $27M | $-34M | $-38M | $-34M | · | · | |
| Income Tax | $2M | $-2M | $666.0K | $0 | $172.0K | $0 | $2M | $-420.0K | $-676.0K | $3M | · | $0 | $0 | $0 | · | · | |
| Net Income | $163M | $4M | $-44M | $-39M | $-35M | $-12M | $132M | $-33M | $-31M | $207M | $27M | $-34M | $-38M | $-34M | $-34M | $-31M | |
| EPS (Basic) | $2.47 | $0.06 | $-0.69 | $-0.62 | $-0.55 | $-0.19 | $2.10 | $-0.54 | $-0.50 | $3.41 | $0.54 | $-0.58 | $-0.68 | $-0.67 | $-0.69 | $-0.64 | |
| EPS (Diluted) | $2.29 | $0.05 | $-0.69 | $-0.62 | $-0.55 | $-0.19 | $2.01 | $-0.54 | $-0.50 | $3.26 | $0.54 | $-0.58 | $-0.68 | $-0.67 | $-0.69 | $-0.64 | |
| Shares (Basic) | 65,935,769 | 65,087,847 | -126,673,627 | 63,772,332 | 63,510,537 | 62,963,806 | -122,361,923 | 61,767,934 | 61,305,289 | 60,855,689 | -109,768,732 | 59,182,899 | 56,775,742 | 50,573,650 | -97,867,857 | 49,107,639 | |
| Shares (Diluted) | 71,007,011 | 70,492,618 | -126,673,627 | 63,772,332 | 63,510,537 | 62,963,806 | -121,590,829 | 61,767,934 | 61,305,289 | 63,595,328 | -109,768,732 | 59,182,899 | 56,775,742 | 50,573,650 | -97,867,857 | 49,107,639 | |
| EBITDA | $159M | $-3M | · | $-46M | $-42M | $-19M | · | $-41M | $-39M | $207M | · | $-38M | $-42M | $-36M | · | $-32M |
资产负债表 21
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $420M | $194M | $128M | $114M | $169M | $140M | $97M | $131M | $356M | $173M | $187M | $231M | $235M | $128M | $126M | $153M | |
| Short-term Investments | $362M | $354M | $439M | $462M | $402M | $435M | $322M | $338M | $208M | $150M | · | $90M | $78M | $103M | · | $115M | |
| Prepaid Expense | $8M | $12M | $10M | $10M | $9M | $9M | $8M | $8M | $7M | $5M | · | $4M | $4M | $5M | · | $9M | |
| Other Current Assets | · | · | $10.0K | $191.0K | $92.0K | · | $248.0K | $3M | $1M | $360.0K | · | $65.0K | · | · | · | · | |
| Current Assets | $807M | $613M | $578M | $586M | $603M | $606M | $592M | $477M | $571M | $628M | · | $325M | $317M | $236M | · | $277M | |
| PP&E (Net) | $3M | $4M | $4M | $4M | $4M | $4M | $3M | $2M | $2M | $1M | · | $1M | $1M | $1M | · | $2M | |
| PP&E (Gross) | $13M | $12M | $12M | $12M | $12M | $11M | $10M | $9M | $8M | $8M | · | $7M | $7M | $7M | · | $7M | |
| Accum. Depreciation | $9M | $9M | $8M | $8M | $8M | $7M | $7M | $7M | $7M | $6M | · | $6M | $6M | $5M | · | $5M | |
| Other Non-current Assets | $832.0K | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Total Assets | $886M | $697M | $668M | $702M | $718M | $742M | $745M | $604M | $615M | $629M | · | $330M | $320M | $240M | · | $282M | |
| Accounts Payable | $3M | $8M | $5M | $6M | $3M | $3M | $2M | $3M | $4M | $4M | · | $1M | $5M | $4M | · | $5M | |
| Accrued Liabilities | $22M | $17M | $28M | $23M | $15M | $12M | $24M | $21M | $15M | $16M | · | $25M | $19M | $17M | · | $30M | |
| Current Liabilities | $37M | $35M | $45M | $45M | $36M | $35M | $47M | $45M | $42M | $40M | · | $28M | $26M | $23M | · | $37M | |
| Capital Leases | $7M | $7M | $8M | $9M | $9M | $10M | $10M | $11M | $11M | · | · | · | · | $462.0K | · | $2M | |
| Total Liabilities | $44M | $42M | $53M | $56M | $50M | $53M | $69M | $72M | $73M | $69M | · | $28M | $26M | $24M | · | $39M | |
| Common Stock | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | · | $1.0K | $1.0K | $1.0K | · | · | |
| Retained Earnings | $-304M | $-467M | $-471M | $-426M | $-387M | $-352M | $-341M | $-472M | $-439M | $-408M | · | $-643M | $-609M | $-570M | · | $-503M | |
| AOCI | $-828.0K | $-269.0K | $641.0K | $525.0K | $-15.0K | $85.0K | $-82.0K | $1M | $-249.0K | $-229.0K | · | $-170.0K | $-198.0K | $-122.0K | · | $-480.0K | |
| Stockholders' Equity | $842M | $655M | $615M | $645M | $668M | $689M | $675M | $532M | $541M | $560M | $337M | $302M | $294M | $216M | $216M | $244M | |
| Liabilities + Equity | $886M | $697M | $668M | $702M | $718M | $742M | $745M | $604M | $615M | $629M | · | $330M | $320M | $240M | · | $282M | |
| Shares Outstanding | 64,672,032 | 64,227,057 | 62,577,897 | 62,447,102 | 62,107,572 | 61,928,760 | 61,035,139 | 59,521,903 | 58,762,063 | 58,600,787 | 57,708,613 | 57,647,476 | 57,494,185 | 51,440,503 | 49,339,252 | 49,198,411 |
现金流 10
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $397.0K | $407.0K | $376.0K | $361.0K | $304.0K | $239.0K | $118.0K | $231.0K | $241.0K | $236.0K | $248.0K | $244.0K | $237.0K | $248.0K | $256.0K | $270.0K | |
| Stock-based Comp | $14M | $15M | $11M | $11M | $11M | $14M | $9M | $10M | $9M | $9M | $7M | $7M | $8M | $8M | $6M | $6M | |
| Other Non-cash | · | $-68M | · | · | · | $123M | · | · | · | $-244M | · | · | · | $-8M | · | · | |
| Operating Cash Flow | $219M | $-49M | $-37M | $-2M | $-29M | $125M | $-29M | $-28M | $269M | $-27M | $17M | $-27M | $-26M | $-34M | $-32M | $-25M | |
| CapEx | $168.0K | $215.0K | $144.0K | $88.0K | $813.0K | $545.0K | $310.0K | $775.0K | $28.0K | $242.0K | $19.0K | $404.0K | $176.0K | $10.0K | $70.0K | $162.0K | |
| Investing Cash Flow | $-2M | $91M | $49M | $-59M | $55M | $-94M | $-9M | $-209M | $-88M | $6M | $-61M | $-14M | $26M | $10M | $4M | $57M | |
| Stock Issued | · | · | · | · | · | · | · | · | · | · | $8.0K | $-78.0K | · | · | · | · | |
| Financing Cash Flow | $10M | $23M | $3M | $6M | $3M | $11M | $4M | $12M | $3M | $7M | $527.0K | $35M | $108M | $26M | $553.0K | $680.0K | |
| Net Change in Cash | $226M | $65M | $15M | $-55M | $29M | $42M | $-34M | $-225M | $183M | $-14M | $-44M | $-5M | $108M | $2M | $-27M | $33M | |
| Free Cash Flow | · | $-49M | · | · | · | $125M | · | · | · | $-28M | · | · | · | $-34M | · | · |
盈利能力 7
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | 74.4% | -6.5% | · | -985.2% | -758.0% | -68.2% | · | -886.7% | -931.0% | 80.9% | · | · | · | · | · | · | |
| Net Margin | 76.3% | 6.7% | · | -834.9% | -627.0% | -41.1% | · | -710.4% | -734.7% | 81.3% | · | · | · | · | · | · | |
| Pretax Margin | 77.3% | 4.0% | · | -834.9% | -623.9% | -41.1% | · | -719.4% | -751.0% | 82.6% | · | · | · | · | · | · | |
| EBITDA Margin | 74.4% | -5.8% | · | -985.2% | -758.0% | -67.3% | · | -886.7% | -931.0% | 81.0% | · | · | · | · | · | · | |
| ROA | 20.3% | 0.53% | · | -6.0% | -5.2% | -1.7% | · | -7.1% | -6.6% | 47.7% | · | -11.1% | -12.2% | -11.5% | · | -9.5% | |
| ROE | 21.6% | 0.56% | · | -6.7% | -5.8% | -1.9% | · | -8.0% | -7.3% | 53.4% | · | -12.5% | -13.7% | -13.0% | · | -10.9% | |
| ROIC | 18.6% | -0.92% | · | -7.2% | -6.3% | -2.8% | · | -7.7% | -7.0% | 36.2% | · | · | · | · | · | · |
流动性与偿付能力 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 21.7 | 17.8 | · | 13.0 | 17.0 | 17.3 | · | 10.7 | 13.7 | 15.7 | · | 11.7 | 12.0 | 10.1 | · | 7.5 | |
| Quick Ratio | 21.0 | 15.9 | · | 12.8 | 16.1 | 16.4 | · | 10.5 | 13.6 | 8.1 | · | 11.5 | 11.9 | 9.9 | · | 7.3 |
效率 1
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.3 | 0.1 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.6 | · | 0.0 | 0.0 | · | · | · |
估值 (TTM) 10
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $280M | $95M | · | $43M | $43M | $292M | · | $264M | $259M | $255M | · | $0 | $859.0K | $27M | · | $37M | |
| Net Income TTM | $93M | $-82M | · | $-119M | $-110M | $132M | · | $109M | $104M | $101M | · | $-138M | $-144M | $-127M | · | $-127M | |
| Market Cap | $7.93B | $6.77B | · | $4.15B | $3.43B | $2.99B | · | $2.68B | $2.04B | $1.70B | · | $962M | $1.59B | $1.18B | · | $415M | |
| P/E | 104.8 | -80.5 | · | -35.0 | -31.1 | 23.8 | · | 27.4 | 23.1 | 21.8 | · | -6.5 | -9.8 | -8.9 | · | -3.2 | |
| P/S | 28.3 | 71.3 | · | 95.9 | 80.4 | 10.3 | · | 10.2 | 7.9 | 6.6 | · | · | 1848.6 | 44.5 | · | 11.2 | |
| P/B | 9.4 | 10.3 | · | 6.4 | 5.1 | 4.3 | · | 5.0 | 3.8 | 3.0 | · | 3.2 | 5.4 | 5.5 | · | 1.7 | |
| P / Tangible Book | 9.4 | 10.3 | · | 6.4 | 5.1 | 4.3 | · | 5.0 | 3.8 | 3.0 | · | 3.2 | 5.4 | 5.5 | · | 1.7 | |
| P / Cash Flow | · | -138.3 | · | · | · | 23.9 | · | · | · | -61.8 | · | · | · | -34.4 | · | · | |
| P / FCF | · | -137.7 | · | · | · | 24.0 | · | · | · | -61.3 | · | · | · | -34.4 | · | · | |
| Earnings Yield | 0.95% | -1.2% | · | -2.9% | -3.2% | 4.2% | · | 3.6% | 4.3% | 4.6% | · | -15.4% | -10.2% | -11.2% | · | -31.0% |
财务报表 损益表、资产负债表、现金流量表 — 年度，近5年
损益表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 收入 | $46M | $434M | $60M | $27M | $27M |
| 营业利润率 % | -343.6% | 58.2% | -156.1% | -494.2% | -460.0% |
| 净收入 | $-130M | $275M | $-79M | $-127M | $-126M |
| 稀释后每股收益 (EPS) | $-2.05 | $4.23 | $-1.39 | $-2.60 | $-2.71 |
资产负债表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 流动比率 | 12.7 | 12.5 | 16.7 | 7.8 | 7.7 |
| 速动比率 | 12.5 | 8.8 | 16.1 | 7.6 | 7.4 |
现金流
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 自由现金流 | $56M | $183M | $-71M | $-109M | $-109M |
最新新闻 提及该公司的近期头条新闻
交易信号 近期买入/卖出信号，包含入场价和风险/回报比
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机构持有人 (13F) 369 家申报者 · $6.0B 总计 · 截至 2026年6月30日
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
机构活动 — Q2 2026 与上一季度对比
| 新仓位 | 已退出持仓 | 增加 | 减少 | 净股数变动 |
|---|---|---|---|---|
| 65 (+5 与上一季度对比) | 34 (-14 与上一季度对比) | 143 (+36 与上一季度对比) | 84 (-28 与上一季度对比) | +6.9M |
与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天，外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过，优先显示最近一个已完整报告的季度对。
公司内部人士 20 位内幕人士 · 9 位高管 · 10 位董事
| 内部人士 | 角色 | 上次活动 | 持股数量 | 买入 12个月 | 卖出 12个月 | 净额 12个月 |
|---|---|---|---|---|---|---|
| Asif Ali | Chief Financial Officer | 2026年4月20日 S | 59003 | 0 | 5 | $-7315451 |
| Donald A. Kalkofen | Chief Financial Officer | 2022年2月15日 A | 18521 | 0 | 0 | $0 |
| Thomas P. O'Neil | Chief Financial Officer | 2018年8月15日 A | 30560 | 0 | 0 | $0 |
| Arturo Molina MD | Chief Medical Officer | 2026年3月26日 M | 84115 | 0 | 6 | $-4491766 |
| Suneel Gupta | Chief Development Officer | 2024年11月26日 M | 267433 | 0 | 0 | $0 |
| David Y Liu | Chief R&D Strategy Officer | 2022年11月16日 M | 167590 | 0 | 0 | $0 |
| Samuel R Saks | Chief Medical Officer | 2021年2月26日 A | 14000 | 0 | 0 | $0 |
| Richard S Shame | Chief Medical Officer | 2019年2月28日 A | 32021 | 0 | 0 | $0 |
| William A Hodder | Sr. VP - Corporate Development | 2016年10月11日 A | — | 0 | 0 | $0 |
| William D. Waddill | 董事 | 2026年6月23日 M | 7825 | 0 | 8 | $-6074420 |
| Bryan Giraudo | 董事 | 2026年5月7日 M | 12695 | 0 | 4 | $-5918880 |
| Harold E Selick | 董事 | 2026年3月26日 M | 60845 | 0 | 1 | $-2520000 |
| Lewis T Williams | 董事 | 2026年2月17日 M | 7825 | 0 | 1 | $-1483560 |
| Sarah A O'Dowd | 董事 | 2026年1月2日 A | 7825 | 0 | 0 | $0 |
| Daniel N Swisher JR | 董事 | 2023年10月26日 A | — | 0 | 0 | $0 |
| Sarah B. Noonberg | 董事 | 2023年1月16日 A | 0 | 0 | 0 | $0 |
| Chaitan Khosla PHD | 董事 | 2020年8月11日 M | 0 | 0 | 0 | $0 |
| Armen Shanafelt | 董事 | 2018年5月29日 A | 2099482 | 0 | 0 | $0 |
| Julie Papanek | 董事 | 2017年5月25日 A | 2453255 | 0 | 0 | $0 |
| PATEL DINESH V PH D | — | 2026年8月11日 M | 523478 | 0 | 11 | $-42337688 |
来自SEC表格3/4/5申报的内部人士；净额=仅公开市场买卖
激进投资者及 5%+ 股东 1 持仓
提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权，意图影响发行人（激进股东持股、董事会活动、并购）。每一行显示该申报人持仓的最新已知状态。
| 申报人 | 已申报 | 持股 | 状态 | 目的 | 申报 |
|---|---|---|---|---|---|
| Lilly Ventures Fund I, LLC, LV Management Group, LLC, S. Edward Torres, Steven E. Hall, Ph.D., Armen B. Shanafelt, Ph.D. ×2 申报 | 2020年6月8日 | — | 初始申报 | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF持仓 由 79 只交易所交易基金持有
权重仅反映直接股权持仓（N-PORT）；杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。
| 基金 | 权重 | 单位 | 截至 | 来源 |
|---|---|---|---|---|
| PSCH · Invesco Exchange-Traded Fund Trus... | 4.59% | 56832 SH | 2026年8月21日 | 每日 |
| PBE · Invesco Exchange-Traded Fund Trust | 3.47% | 91589 SH | 2026年8月21日 | 每日 |
| NBDS · Neuberger Berman ETF Trust | 2.97% | 10761 NS | 2026年5月31日 | N-PORT |
| XSMO · Invesco Exchange-Traded Fund Trust | 2.88% | 576170 SH | 2026年8月21日 | 每日 |
| CAFG · Pacer Funds Trust | 2.15% | 4916 NS | 2026年4月30日 | N-PORT |
| RZG · Invesco Exchange-Traded Fund Trust | 1.98% | 17525 SH | 2026年8月21日 | 每日 |
| LABU · Direxion Shares ETF Trust | 0.96% | 50321 NS | 2026年4月30日 | N-PORT |
| VAMO · Cambria ETF Trust | 0.82% | 6865 NS | 2026年4月30日 | N-PORT |
| VIOG · VANGUARD ADMIRAL FUNDS | 0.81% | 71955 SH | 2026年8月19日 | 每日 |
| BBC · ETFis Series Trust I | 0.77% | 2894 NS | 2026年4月30日 | N-PORT |
| FDMO · FIDELITY COVINGTON TRUST | 0.72% | 61466 NS | 2026年4月30日 | N-PORT |
| IBB · iShares Trust | 0.65% | 456115 SH | 2026年8月21日 | 每日 |
| FTXH · First Trust Exchange-Traded Fund VI | 0.62% | 1844 NS | 2026年6月30日 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trus... | 0.62% | 3786 SH | 2026年8月21日 | 每日 |
| IWO · iShares Trust | 0.58% | 571552 SH | 2026年8月21日 | 每日 |
| QVMS · Invesco Exchange-Traded Fund Trus... | 0.53% | 8846 SH | 2026年8月21日 | 每日 |
| PSC · Principal Exchange-Traded Funds | 0.47% | 88659 NS | 2026年6月30日 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.44% | 65879 SH | 2026年8月19日 | 每日 |
| ESSC · Strategy Shares | 0.41% | 1068 NS | 2026年4月30日 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund ... | 0.41% | 2139 NS | 2026年5月31日 | N-PORT |
| VIOO · VANGUARD ADMIRAL FUNDS | 0.40% | 211363 SH | 2026年8月19日 | 每日 |
| FNY · First Trust Exchange-Traded Alpha... | 0.37% | 19517 NS | 2026年4月30日 | N-PORT |
| AFSM · First Trust Exchange-Traded Fund ... | 0.33% | 3261 NS | 2026年5月31日 | N-PORT |
| BIB · ProShares Trust | 0.32% | 2361 NS | 2026年5月31日 | N-PORT |
| JPSE · J.P. Morgan Exchange-Traded Fund ... | 0.29% | 17406 NS | 2026年4月30日 | N-PORT |
| IWM · iShares Trust | 0.29% | 1568045 SH | 2026年8月21日 | 每日 |
| BBSC · J.P. Morgan Exchange-Traded Fund ... | 0.27% | 20237 NS | 2026年4月30日 | N-PORT |
| BKSE · BNY Mellon ETF Trust | 0.26% | 2151 NS | 2026年4月30日 | N-PORT |
| SAA · ProShares Trust | 0.26% | 705 NS | 2026年5月31日 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.23% | 354172 SH | 2026年8月19日 | 每日 |
| VBK · VANGUARD INDEX FUNDS | 0.22% | 851812 SH | 2026年8月19日 | 每日 |
| VFMO · VANGUARD WELLINGTON FUND | 0.17% | 27056 SH | 2026年8月19日 | 每日 |
| ROSC · Lattice Strategies Trust | 0.17% | 917 NS | 2026年4月30日 | N-PORT |
| RB · ProShares Trust | 0.15% | 18 NS | 2026年5月31日 | N-PORT |
| ISCV · iShares Trust | 0.15% | 6767 SH | 2026年8月21日 | 每日 |
| ITWO · ProShares Trust | 0.15% | 2739 NS | 2026年5月31日 | N-PORT |
| ESML · iShares Trust | 0.13% | 24688 SH | 2026年8月21日 | 每日 |
| FNX · First Trust Exchange-Traded Alpha... | 0.13% | 17224 NS | 2026年4月30日 | N-PORT |
| ESUM · Strategy Shares | 0.13% | 1964 NS | 2026年4月30日 | N-PORT |
| ISCB · iShares Trust | 0.12% | 2384 SH | 2026年8月21日 | 每日 |
| SCHA · SCHWAB STRATEGIC TRUST | 0.12% | 282329 NS | 2026年5月31日 | N-PORT |
| FAD · First Trust Exchange-Traded Alpha... | 0.11% | 5370 NS | 2026年4月30日 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.11% | 20475 SH | 2026年8月21日 | 每日 |
| ISCG · iShares Trust | 0.11% | 7026 SH | 2026年8月21日 | 每日 |
| VB · VANGUARD INDEX FUNDS | 0.09% | 1475028 SH | 2026年8月19日 | 每日 |
| VHT · VANGUARD WORLD FUND | 0.09% | 153362 SH | 2026年8月19日 | 每日 |
| UWM · ProShares Trust | 0.09% | 2143 NS | 2026年5月31日 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0.08% | 8339 NS | 2026年5月31日 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0.08% | 23132 NS | 2026年4月30日 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.08% | 693286 SH | 2026年8月19日 | 每日 |