| RTW INVESTMENTS, LP |
$60492180 |
17687772 |
15.98% |
股份
|
| BlackRock, Inc. |
$33939951 |
9923962 |
8.97% |
股份
|
| VANGUARD GROUP INC |
$29990925 |
8544423 |
7.92% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$19870313 |
5810033 |
5.25% |
股份
|
| CITIGROUP INC |
$16640184 |
4865551 |
4.40% |
股份
|
| MARSHALL WACE, LLP |
$13780075 |
4029262 |
3.64% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$13681176 |
4000344 |
3.61% |
股份
|
| Newtyn Management, LLC |
$13680000 |
4000000 |
3.61% |
股份
|
| MAVERICK CAPITAL LTD |
$13419953 |
3923963 |
3.55% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$12942604 |
3784387 |
3.42% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$11580675 |
3386162 |
3.06% |
股份
|
| GOLDMAN SACHS GROUP INC |
$9690320 |
2833427 |
2.56% |
股份
|
| Monaco Asset Management SAM |
$8483201 |
2480468 |
2.24% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$8109758 |
2370729 |
2.14% |
股份
|
| FEDERATED HERMES, INC. |
$7880388 |
2304207 |
2.08% |
股份
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$6754144 |
1974896 |
1.78% |
股份
|
| JPMORGAN CHASE & CO |
$6700952 |
1988413 |
1.77% |
股份
|
| TWO SIGMA ADVISERS, LP |
$6544925 |
1864651 |
1.73% |
股份
|
| STATE STREET CORP |
$6224814 |
1820121 |
1.64% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$3848757 |
1125500 |
1.02% |
股份
|
| MORGAN STANLEY |
$3633827 |
1062522 |
0.96% |
股份
|
| Opaleye Management Inc. |
$3420000 |
1000000 |
0.90% |
股份
|
| D. E. Shaw & Co., Inc. |
$3250888 |
950552 |
0.86% |
股份
|
| Jump Financial, LLC |
$2968218 |
867900 |
0.78% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$2711971 |
792974 |
0.72% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$2561830 |
749073 |
0.68% |
股份
|
| NORTHERN TRUST CORP |
$2514008 |
735090 |
0.66% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$2512277 |
734584 |
0.66% |
股份
|
| Prosight Management, LP |
$2394000 |
700000 |
0.63% |
股份
|
| Point72 Asset Management, L.P. |
$2293202 |
670527 |
0.61% |
股份
|
| Qube Research & Technologies Ltd |
$2205452 |
644869 |
0.58% |
股份
|
| Woodline Partners LP |
$2192979 |
641222 |
0.58% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$2027526 |
592844 |
0.54% |
股份
|
| FMR LLC |
$1669981 |
488299 |
0.44% |
股份
|
| IEQ CAPITAL, LLC |
$1505672 |
440255 |
0.40% |
股份
|
| ADAR1 Capital Management, LLC |
$1489410 |
435500 |
0.39% |
股份
|
| Aberdeen Group plc |
$1360226 |
397727 |
0.36% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$1323762 |
387065 |
0.35% |
股份
|
| Invesco Ltd. |
$1310941 |
383316 |
0.35% |
股份
|
| LOS ANGELES CAPITAL MANAGEMENT LLC |
$1190479 |
348093 |
0.31% |
股份
|
| Susquehanna Portfolio Strategies, LLC |
$1135803 |
332106 |
0.30% |
股份
|
| LPL Financial LLC |
$1100679 |
321836 |
0.29% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$1079903 |
315761 |
0.29% |
股份
|
| BIT Capital GmbH |
$1019160 |
298000 |
0.27% |
股份
|
| AMERIPRISE FINANCIAL INC |
$940531 |
275009 |
0.25% |
股份
|
| Bank of New York Mellon Corp |
$888548 |
259809 |
0.23% |
股份
|
| Privium Fund Management B.V. |
$834979 |
244146 |
0.22% |
股份
|
| M28 Capital Management LP |
$721179 |
210871 |
0.19% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$700427 |
195650 |
0.19% |
股份
|
| UBS Group AG |
$689616 |
201642 |
0.18% |
股份
|
| Nuveen, LLC |
$683295 |
199794 |
0.18% |
股份
|
| Mariner, LLC |
$679402 |
198662 |
0.18% |
股份
|
| PDT Partners, LLC |
$638158 |
186596 |
0.17% |
股份
|
| CWM, LLC |
$623862 |
174263 |
0.16% |
股份
|
| Squarepoint Ops LLC |
$619523 |
181147 |
0.16% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$612864 |
179200 |
0.16% |
买入期权
|
| Amitell Capital Pte Ltd |
$611390 |
178769 |
0.16% |
股份
|
| RAYMOND JAMES FINANCIAL INC |
$542077 |
158502 |
0.14% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$521998 |
152631 |
0.14% |
股份
|
| Russell Investments Group, Ltd. |
$516190 |
150933 |
0.14% |
股份
|
| GOLDMAN SACHS GROUP INC |
$478800 |
140000 |
0.13% |
买入期权
|
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO |
$462042 |
135100 |
0.12% |
股份
|
| Jain Global LLC |
$460554 |
134665 |
0.12% |
股份
|
| Creative Planning |
$450014 |
131583 |
0.12% |
股份
|
| Virtus Investment Advisers, LLC |
$406915 |
118981 |
0.11% |
股份
|
| RHUMBLINE ADVISERS |
$381017 |
111412 |
0.10% |
股份
|
| Schonfeld Strategic Advisors LLC |
$378476 |
110666 |
0.10% |
股份
|
| MERCER GLOBAL ADVISORS INC /ADV |
$369456 |
108028 |
0.10% |
股份
|
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
$358031 |
91568 |
0.09% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$347520 |
101614 |
0.09% |
股份
|
| TANG CAPITAL MANAGEMENT LLC |
$342000 |
100000 |
0.09% |
股份
|
| RICE HALL JAMES & ASSOCIATES, LLC |
$329924 |
96469 |
0.09% |
股份
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$323966 |
94727 |
0.09% |
股份
|
| Balyasny Asset Management L.P. |
$322383 |
94264 |
0.09% |
股份
|
| Cerity Partners LLC |
$314042 |
91825 |
0.08% |
股份
|
| Weiss Asset Management LP |
$294339 |
86064 |
0.08% |
股份
|
| Lion Point Capital, LP |
$294120 |
86000 |
0.08% |
股份
|
| Assenagon Asset Management S.A. |
$290067 |
84815 |
0.08% |
股份
|
| DEUTSCHE BANK AG\ |
$287885 |
84177 |
0.08% |
股份
|
| WELLS FARGO & COMPANY/MN |
$284154 |
83086 |
0.08% |
股份
|
| Marex Group Ltd |
$247950 |
72500 |
0.07% |
股份
|
| Nebula Research & Development LLC |
$246911 |
100780 |
0.07% |
股份
|
| Engineers Gate Manager LP |
$244698 |
71549 |
0.06% |
股份
|
| PIER 88 INVESTMENT PARTNERS LLC |
$244530 |
71500 |
0.06% |
股份
|
| CITADEL ADVISORS LLC |
$243401 |
71170 |
0.06% |
股份
|
| Ballentine Partners, LLC |
$240785 |
70405 |
0.06% |
股份
|
| BANK OF MONTREAL /CAN/ |
$240765 |
70399 |
0.06% |
股份
|
| Concurrent Investment Advisors, LLC |
$224752 |
65717 |
0.06% |
股份
|
| CITADEL ADVISORS LLC |
$222300 |
65000 |
0.06% |
买入期权
|
| WELLINGTON MANAGEMENT GROUP LLP |
$210689 |
61605 |
0.06% |
股份
|
| Walleye Capital LLC |
$206606 |
60411 |
0.05% |
股份
|
| Velan Capital Investment Management LP |
$205200 |
60000 |
0.05% |
股份
|
| CANADA PENSION PLAN INVESTMENT BOARD |
$200070 |
58500 |
0.05% |
股份
|
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. |
$198000 |
58000 |
0.05% |
股份
|
| Arax Advisory Partners |
$180422 |
52755 |
0.05% |
股份
|
| TUDOR INVESTMENT CORP ET AL |
$172686 |
50493 |
0.05% |
股份
|
| WOLVERINE TRADING, LLC |
$159080 |
48500 |
0.04% |
买入期权
|
| MetLife Investment Management, LLC |
$156144 |
45656 |
0.04% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$134526 |
39335 |
0.04% |
股份
|
| Quantinno Capital Management LP |
$132286 |
38680 |
0.03% |
股份
|
| CAPTRUST FINANCIAL ADVISORS |
$131208 |
38365 |
0.03% |
股份
|
| Corient Private Wealth LP |
$129341 |
37819 |
0.03% |
股份
|
| Rockefeller Capital Management L.P. |
$119417 |
34917 |
0.03% |
股份
|
| BRIGHTON JONES LLC |
$112816 |
32987 |
0.03% |
股份
|
| Voleon Capital Management LP |
$111006 |
32458 |
0.03% |
股份
|
| Vanguard Global Advisers, LLC |
$104731 |
30623 |
0.03% |
股份
|
| COMMONWEALTH EQUITY SERVICES, LLC |
$100960 |
29520 |
0.03% |
股份
|
| Focus Partners Wealth |
$100708 |
29447 |
0.03% |
股份
|
| AlphaQuest LLC |
$99108 |
28236 |
0.03% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$98154 |
28700 |
0.03% |
卖出期权
|
| STIFEL FINANCIAL CORP |
$94392 |
27600 |
0.02% |
股份
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$90503 |
26463 |
0.02% |
股份
|
| Dynamic Technology Lab Private Ltd |
$80000 |
23398 |
0.02% |
股份
|
| INTECH INVESTMENT MANAGEMENT LLC |
$79081 |
23123 |
0.02% |
股份
|
| BARCLAYS PLC |
$77689 |
22716 |
0.02% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$75616 |
22110 |
0.02% |
股份
|
| SEI INVESTMENTS CO |
$75289 |
22016 |
0.02% |
股份
|
| Merit Financial Group, LLC |
$66211 |
19360 |
0.02% |
股份
|
| MAI Capital Management |
$63903 |
18685 |
0.02% |
股份
|
| ExodusPoint Capital Management, LP |
$63732 |
18635 |
0.02% |
股份
|
| VOYA INVESTMENT MANAGEMENT LLC |
$63468 |
18558 |
0.02% |
股份
|
| Sequoia Financial Advisors, LLC |
$60374 |
17653 |
0.02% |
股份
|
| China Universal Asset Management Co., Ltd. |
$59433 |
17378 |
0.02% |
股份
|
| Integrated Wealth Concepts LLC |
$57258 |
16742 |
0.02% |
股份
|
| Steward Partners Investment Advisory, LLC |
$55883 |
16340 |
0.01% |
股份
|
| Vanguard Personalized Indexing Management, LLC |
$55117 |
16116 |
0.01% |
股份
|
| ProShare Advisors LLC |
$52740 |
15421 |
0.01% |
股份
|
| WINTON GROUP Ltd |
$51984 |
15200 |
0.01% |
股份
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$51700 |
15117 |
0.01% |
股份
|
| PRUDENTIAL FINANCIAL INC |
$51454 |
15045 |
0.01% |
股份
|
| Krilogy Financial LLC |
$48889 |
14295 |
0.01% |
股份
|
| Pallas Capital Advisors LLC |
$46926 |
13721 |
0.01% |
股份
|
| WOLVERINE TRADING, LLC |
$44936 |
13700 |
0.01% |
卖出期权
|
| Skopos Labs, Inc. |
$42334 |
11825 |
0.01% |
股份
|
| GRIMES & Co WEALTH MANAGEMENT, LLC |
$41043 |
12001 |
0.01% |
股份
|
| VICTORY CAPITAL MANAGEMENT INC |
$40931 |
11968 |
0.01% |
股份
|
| Focus Partners Advisor Solutions, LLC |
$40619 |
11877 |
0.01% |
股份
|
| a16z Perennial Management, L.P. |
$38766 |
11335 |
0.01% |
股份
|
| HB Wealth Management, LLC |
$36050 |
10541 |
0.01% |
股份
|
| XTX Topco Ltd |
$35185 |
10288 |
0.01% |
股份
|
| FRANKLIN RESOURCES INC |
$34768 |
10166 |
0.01% |
股份
|
| Legal & General Group Plc |
$31379 |
9175 |
0.01% |
股份
|
| Allworth Financial LP |
$28051 |
8202 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$26666 |
7797 |
0.01% |
股份
|
| Tower Research Capital LLC (TRC) |
$23112 |
6758 |
0.01% |
股份
|
| EverSource Wealth Advisors, LLC |
$18944 |
5539 |
0.01% |
股份
|
| PNC Financial Services Group, Inc. |
$18725 |
5475 |
0.00% |
股份
|
| Mirae Asset Global Investments Co., Ltd. |
$16703 |
4884 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$14135 |
4133 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$14012 |
4097 |
0.00% |
股份
|
| Lindbrook Capital, LLC |
$13580 |
2036 |
0.00% |
股份
|
| Essential Partners LLC |
$12462 |
3644 |
0.00% |
股份
|
| Zurcher Kantonalbank (Zurich Cantonalbank) |
$12165 |
3557 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$9037 |
2655 |
0.00% |
股份
|
| ROYAL BANK OF CANADA |
$9000 |
2746 |
0.00% |
股份
|
| JONES FINANCIAL COMPANIES LLLP |
$8986 |
2765 |
0.00% |
股份
|
| SIGNATUREFD, LLC |
$8413 |
2460 |
0.00% |
股份
|
| GF FUND MANAGEMENT CO. LTD. |
$7866 |
2300 |
0.00% |
股份
|
| Optiver Holding B.V. |
$6389 |
1868 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$6371 |
1863 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$6235 |
1823 |
0.00% |
股份
|
| IFP Advisors, Inc |
$6218 |
1818 |
0.00% |
股份
|
| OSAIC HOLDINGS, INC. |
$5411 |
1582 |
0.00% |
股份
|
| Owl Creek Wealth Partners LLC |
$4446 |
1300 |
0.00% |
股份
|
| GAMMA Investing LLC |
$4148 |
1213 |
0.00% |
股份
|
| US BANCORP \DE\ |
$4097 |
1198 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$4060 |
1187 |
0.00% |
股份
|
| True Wealth Design, LLC |
$2986 |
873 |
0.00% |
股份
|
| Parallel Advisors, LLC |
$2880 |
842 |
0.00% |
股份
|
| Sankala Group LLC |
$2738 |
828 |
0.00% |
股份
|
| NewEdge Advisors, LLC |
$2394 |
700 |
0.00% |
股份
|
| Physician Wealth Advisors, Inc. |
$1943 |
568 |
0.00% |
股份
|
| SJS Investment Consulting Inc. |
$1632 |
477 |
0.00% |
股份
|
| Wealth Enhancement Trust Services, Inc. |
$1570 |
459 |
0.00% |
股份
|
| Bare Financial Services, Inc |
$1163 |
340 |
0.00% |
股份
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$934 |
261 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$910 |
266 |
0.00% |
股份
|
| ZIONS BANCORPORATION, NATIONAL ASSOCIATION /UT/ |
$691 |
202 |
0.00% |
股份
|
| FIFTH THIRD BANCORP |
$661 |
193 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$641 |
187415 |
0.00% |
股份
|
| COMERICA BANK |
$477 |
136 |
0.00% |
股份
|
| Pinnacle Wealth Planning Services, Inc. |
$451 |
132 |
0.00% |
股份
|
| Larson Financial Group LLC |
$438 |
128 |
0.00% |
股份
|
| Clearstead Advisors, LLC |
$419 |
122 |
0.00% |
股份
|
| MassMutual Private Wealth & Trust, FSB |
$390 |
114 |
0.00% |
股份
|
| Sunbelt Securities, Inc. |
$322 |
90 |
0.00% |
股份
|
| JPL Wealth Management, LLC |
$226 |
66 |
0.00% |
股份
|
| Global Retirement Partners, LLC |
$65 |
19 |
0.00% |
股份
|
| SG Americas Securities, LLC |
$64 |
18819 |
0.00% |
股份
|
| CANADA LIFE ASSURANCE Co |
$61 |
17723 |
0.00% |
股份
|
| Virtu Financial LLC |
$40 |
11562 |
0.00% |
股份
|
| GILL CAPITAL PARTNERS, LLC |
$14 |
4 |
0.00% |
股份
|
| Covestor Ltd |
$0 |
89 |
0.00% |
股份
|