| GILEAD SCIENCES, INC. |
$968825351 |
31424760 |
24.50% |
股份
|
| BlackRock, Inc. |
$506112958 |
16416249 |
12.80% |
股份
|
| VANGUARD GROUP INC |
$189755288 |
7962874 |
4.80% |
股份
|
| STATE STREET CORP |
$185888992 |
6029484 |
4.70% |
股份
|
| WELLINGTON MANAGEMENT GROUP LLP |
$181756661 |
5895448 |
4.60% |
股份
|
| MONTANOVA CAPITAL, LLC |
$147257121 |
4776423 |
3.72% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$137980528 |
4475528 |
3.49% |
股份
|
| FMR LLC |
$124854021 |
4049757 |
3.16% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$119877707 |
3888346 |
3.03% |
股份
|
| CITADEL ADVISORS LLC |
$96653807 |
3135057 |
2.44% |
股份
|
| Woodline Partners LP |
$92730412 |
3007798 |
2.35% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$75507790 |
2448749 |
1.91% |
股份
|
| Siren, L.L.C. |
$74621857 |
2420430 |
1.89% |
股份
|
| Fisher Asset Management, LLC |
$65957578 |
2139396 |
1.67% |
股份
|
| MARSHALL WACE, LLP |
$59967064 |
1945088 |
1.52% |
股份
|
| SAMLYN CAPITAL, LLC |
$47699621 |
1547182 |
1.21% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$44221943 |
1434320 |
1.12% |
股份
|
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. |
$43764202 |
1419533 |
1.11% |
股份
|
| GOLDMAN SACHS GROUP INC |
$42778660 |
1387566 |
1.08% |
股份
|
| Soleus Capital Management, L.P. |
$36032193 |
1168738 |
0.91% |
股份
|
| Sofinnova Investments, Inc. |
$29155623 |
945690 |
0.74% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$29034337 |
941756 |
0.73% |
股份
|
| NORTHERN TRUST CORP |
$28749685 |
932523 |
0.73% |
股份
|
| Parkman Healthcare Partners LLC |
$28340971 |
919266 |
0.72% |
股份
|
| Invesco Ltd. |
$26058533 |
845233 |
0.66% |
股份
|
| BAKER BROS. ADVISORS LP |
$26045677 |
844816 |
0.66% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$25758589 |
835504 |
0.65% |
股份
|
| MORGAN STANLEY |
$24537986 |
795912 |
0.62% |
股份
|
| Candriam S.C.A. |
$20389238 |
661981 |
0.52% |
股份
|
| Aberdeen Group plc |
$20061451 |
650712 |
0.51% |
股份
|
| Logos Global Management LP |
$20039500 |
650000 |
0.51% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$19589505 |
635404 |
0.50% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$18993993 |
616088 |
0.48% |
股份
|
| Bank of New York Mellon Corp |
$16740979 |
543009 |
0.42% |
股份
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$15787550 |
512084 |
0.40% |
股份
|
| Ikarian Capital, LLC |
$15555555 |
504559 |
0.39% |
股份
|
| Decheng Capital LLC |
$14329137 |
464779 |
0.36% |
股份
|
| DAFNA Capital Management LLC |
$13621588 |
441829 |
0.34% |
股份
|
| JPMORGAN CHASE & CO |
$13121105 |
418243 |
0.33% |
股份
|
| PRINCIPAL FINANCIAL GROUP INC |
$13052373 |
423366 |
0.33% |
股份
|
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. |
$11688000 |
379100 |
0.30% |
股份
|
| UBS Group AG |
$11377996 |
369056 |
0.29% |
股份
|
| Patient Square Capital LP |
$10969314 |
355800 |
0.28% |
股份
|
| PDT Partners, LLC |
$9975571 |
323567 |
0.25% |
股份
|
| Public Sector Pension Investment Board |
$9192149 |
298156 |
0.23% |
股份
|
| FIRST TRUST ADVISORS LP |
$8368310 |
271434 |
0.21% |
股份
|
| Nuveen, LLC |
$7215824 |
234052 |
0.18% |
股份
|
| Connor, Clark & Lunn Investment Management Ltd. |
$6936997 |
225008 |
0.18% |
股份
|
| DIADEMA PARTNERS LP |
$6900062 |
223810 |
0.17% |
股份
|
| RHUMBLINE ADVISERS |
$6757319 |
219181 |
0.17% |
股份
|
| Ensign Peak Advisors, Inc |
$6647349 |
215613 |
0.17% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$5981020 |
194000 |
0.15% |
买入期权
|
| Legal & General Group Plc |
$5905796 |
191560 |
0.15% |
股份
|
| Cutter Capital Management, LP |
$5744771 |
731818 |
0.15% |
股份
|
| Rock Springs Capital Management LP |
$5549400 |
180000 |
0.14% |
股份
|
| Swiss National Bank |
$5429040 |
176096 |
0.14% |
股份
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$4755959 |
154264 |
0.12% |
股份
|
| AMERIPRISE FINANCIAL INC |
$4742054 |
153813 |
0.12% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$4720350 |
153109 |
0.12% |
股份
|
| PFM Health Sciences, LP |
$4690137 |
152129 |
0.12% |
股份
|
| Hudson Bay Capital Management LP |
$4316200 |
140000 |
0.11% |
股份
|
| Man Group plc |
$4247233 |
137763 |
0.11% |
股份
|
| PLATINUM INVESTMENT MANAGEMENT LTD |
$4137910 |
134217 |
0.10% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$4103781 |
133110 |
0.10% |
股份
|
| DIADEMA PARTNERS LP |
$3822920 |
124000 |
0.10% |
买入期权
|
| Schonfeld Strategic Advisors LLC |
$3778956 |
122574 |
0.10% |
股份
|
| CITIGROUP INC |
$3460298 |
112238 |
0.09% |
股份
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$3419108 |
158292 |
0.09% |
股份
|
| SECTORAL ASSET MANAGEMENT INC |
$3418122 |
110870 |
0.09% |
股份
|
| PRUDENTIAL FINANCIAL INC |
$3409890 |
110603 |
0.09% |
股份
|
| AXA Investment Managers S.A. |
$3164285 |
232668 |
0.08% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$3003150 |
97410 |
0.08% |
股份
|
| D. E. Shaw & Co., Inc. |
$2972536 |
96417 |
0.08% |
股份
|
| DEUTSCHE BANK AG\ |
$2919909 |
94710 |
0.07% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$2742660 |
126975 |
0.07% |
股份
|
| Parallel Advisors, LLC |
$2668552 |
86557 |
0.07% |
股份
|
| Odyssean, LLC |
$2635873 |
85497 |
0.07% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$2585435 |
83861 |
0.07% |
股份
|
| WELLS FARGO & COMPANY/MN |
$2556207 |
82913 |
0.06% |
股份
|
| Allianz Asset Management GmbH |
$2542180 |
82458 |
0.06% |
股份
|
| STATE OF WISCONSIN INVESTMENT BOARD |
$2540361 |
82399 |
0.06% |
股份
|
| Jump Financial, LLC |
$2529170 |
82036 |
0.06% |
股份
|
| Russell Investments Group, Ltd. |
$2514157 |
81549 |
0.06% |
股份
|
| Knott David M Jr |
$2504660 |
81241 |
0.06% |
股份
|
| Rafferty Asset Management, LLC |
$2211282 |
71725 |
0.06% |
股份
|
| VANGUARD ASSET MANAGEMENT, Ltd |
$1958568 |
63528 |
0.05% |
股份
|
| Caption Management, LLC |
$1911460 |
62000 |
0.05% |
股份
|
| FRED ALGER MANAGEMENT, LLC |
$1865030 |
60494 |
0.05% |
股份
|
| BIT Capital GmbH |
$1849800 |
60000 |
0.05% |
股份
|
| Corient Private Wealth LP |
$1822886 |
59127 |
0.05% |
股份
|
| Zurcher Kantonalbank (Zurich Cantonalbank) |
$1819617 |
59021 |
0.05% |
股份
|
| Quantinno Capital Management LP |
$1765172 |
57255 |
0.04% |
股份
|
| Persistent Asset Partners Ltd |
$1758790 |
57048 |
0.04% |
股份
|
| RAYMOND JAMES FINANCIAL INC |
$1654955 |
53680 |
0.04% |
股份
|
| Susquehanna Portfolio Strategies, LLC |
$1654584 |
53668 |
0.04% |
股份
|
| WINTON GROUP Ltd |
$1615430 |
52398 |
0.04% |
股份
|
| MetLife Investment Management, LLC |
$1606551 |
52110 |
0.04% |
股份
|
| Illinois Municipal Retirement Fund |
$1578928 |
51214 |
0.04% |
股份
|
| SummitTX Capital, L.P. |
$1555774 |
50463 |
0.04% |
股份
|
| Burkehill Global Management, LP |
$1541500 |
50000 |
0.04% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$1528970 |
49526 |
0.04% |
股份
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$1412816 |
45826 |
0.04% |
股份
|
| Vanguard Global Advisers, LLC |
$1248615 |
40500 |
0.03% |
股份
|
| PROFUND ADVISORS LLC |
$1218772 |
39532 |
0.03% |
股份
|
| STRS OHIO |
$1211619 |
39300 |
0.03% |
股份
|
| Louisiana State Employees Retirement System |
$1171540 |
38000 |
0.03% |
股份
|
| VIRGINIA RETIREMENT SYSTEMS ET Al |
$1151501 |
37350 |
0.03% |
股份
|
| JANE STREET GROUP, LLC |
$1137627 |
36900 |
0.03% |
买入期权
|
| INTECH INVESTMENT MANAGEMENT LLC |
$1105008 |
35842 |
0.03% |
股份
|
| Trexquant Investment LP |
$1016989 |
32987 |
0.03% |
股份
|
| Universal- Beteiligungs- und Servicegesellschaft mbH |
$1004780 |
32591 |
0.03% |
股份
|
| State of Tennessee, Department of Treasury |
$999386 |
32416 |
0.03% |
股份
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$969727 |
31454 |
0.02% |
股份
|
| Creative Planning |
$966273 |
31342 |
0.02% |
股份
|
| NOMURA HOLDINGS INC |
$924900 |
30000 |
0.02% |
买入期权
|
| NOMURA HOLDINGS INC |
$924900 |
30000 |
0.02% |
卖出期权
|
| JANUS HENDERSON GROUP PLC |
$916406 |
42338 |
0.02% |
股份
|
| State of New Jersey Common Pension Fund D |
$874678 |
28371 |
0.02% |
股份
|
| TEMA ETFS LLC |
$860859 |
36125 |
0.02% |
股份
|
| CITADEL ADVISORS LLC |
$838576 |
27200 |
0.02% |
买入期权
|
| Shay Capital LLC |
$813912 |
26400 |
0.02% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$813450 |
26385 |
0.02% |
股份
|
| ARIZONA STATE RETIREMENT SYSTEM |
$746425 |
24211 |
0.02% |
股份
|
| YOUSIF CAPITAL MANAGEMENT, LLC |
$715318 |
23202 |
0.02% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$706007 |
22900 |
0.02% |
卖出期权
|
| Balyasny Asset Management L.P. |
$704311 |
22845 |
0.02% |
股份
|
| LPL Financial LLC |
$692103 |
22449 |
0.02% |
股份
|
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ |
$670553 |
21750 |
0.02% |
股份
|
| Vanguard Investments Australia, Ltd. |
$653812 |
21207 |
0.02% |
股份
|
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS |
$634451 |
20579 |
0.02% |
股份
|
| Allspring Global Investments Holdings, LLC |
$629415 |
21764 |
0.02% |
股份
|
| FIFTH THIRD BANCORP |
$611113 |
19822 |
0.02% |
股份
|
| OREGON PUBLIC EMPLOYEES RETIREMENT FUND |
$609848 |
19781 |
0.02% |
股份
|
| TD Asset Management Inc |
$609632 |
19774 |
0.02% |
股份
|
| BARCLAYS PLC |
$595575 |
19318 |
0.02% |
股份
|
| KLP KAPITALFORVALTNING AS |
$595019 |
19300 |
0.02% |
股份
|
| Blackstone Inc. |
$546153 |
17715 |
0.01% |
股份
|
| VOYA INVESTMENT MANAGEMENT LLC |
$530307 |
17201 |
0.01% |
股份
|
| Squarepoint Ops LLC |
$467105 |
15151 |
0.01% |
股份
|
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM |
$464670 |
15072 |
0.01% |
股份
|
| COMERICA BANK |
$455367 |
19109 |
0.01% |
股份
|
| SEI INVESTMENTS CO |
$435041 |
14111 |
0.01% |
股份
|
| VICTORY CAPITAL MANAGEMENT INC |
$428537 |
13900 |
0.01% |
股份
|
| Virtus Investment Advisers, LLC |
$423851 |
13748 |
0.01% |
股份
|
| EntryPoint Capital, LLC |
$407696 |
13224 |
0.01% |
股份
|
| Rockefeller Capital Management L.P. |
$392528 |
12732 |
0.01% |
股份
|
| ProShare Advisors LLC |
$392405 |
12728 |
0.01% |
股份
|
| Bayforest Capital Ltd |
$391818 |
12709 |
0.01% |
股份
|
| Maryland State Retirement & Pension System |
$391109 |
12686 |
0.01% |
股份
|
| Marex Group Ltd |
$383525 |
12440 |
0.01% |
股份
|
| Pictet Asset Management Holding SA |
$353373 |
11462 |
0.01% |
股份
|
| TEACHER RETIREMENT SYSTEM OF TEXAS |
$315544 |
10235 |
0.01% |
股份
|
| E Fund Management Co., Ltd. |
$311784 |
10113 |
0.01% |
股份
|
| CAPSTONE INVESTMENT ADVISORS, LLC |
$309811 |
10049 |
0.01% |
股份
|
| Verition Fund Management LLC |
$308300 |
10000 |
0.01% |
股份
|
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC |
$306419 |
9939 |
0.01% |
股份
|
| Campbell & CO Investment Adviser LLC |
$290049 |
9408 |
0.01% |
股份
|
| VARCOV Co. |
$278179 |
9023 |
0.01% |
股份
|
| Vanguard Personalized Indexing Management, LLC |
$275158 |
8925 |
0.01% |
股份
|
| XPONANCE LLC |
$273555 |
8873 |
0.01% |
股份
|
| INCEPTIONR LLC |
$267512 |
8677 |
0.01% |
股份
|
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
$262565 |
9079 |
0.01% |
股份
|
| AXQ CAPITAL, LP |
$254471 |
8254 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$250309 |
8119 |
0.01% |
股份
|
| ROYAL BANK OF CANADA |
$240000 |
7812 |
0.01% |
股份
|
| BANK OF MONTREAL /CAN/ |
$231595 |
7512 |
0.01% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$230855 |
7488 |
0.01% |
股份
|
| Tower Research Capital LLC (TRC) |
$225922 |
7328 |
0.01% |
股份
|
| PNC Financial Services Group, Inc. |
$223734 |
7257 |
0.01% |
股份
|
| Seelaus Asset Management LLC |
$201628 |
6540 |
0.01% |
股份
|
| AlphaQuest LLC |
$173959 |
7300 |
0.00% |
股份
|
| State of Wyoming |
$141756 |
4598 |
0.00% |
股份
|
| GAMMA Investing LLC |
$122272 |
3966 |
0.00% |
股份
|
| CWM, LLC |
$115646 |
5354 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$102541 |
3326 |
0.00% |
股份
|
| Persistent Asset Partners Ltd |
$97960 |
316 |
0.00% |
买入期权
|
| Pinnacle Wealth Planning Services, Inc. |
$83673 |
2714 |
0.00% |
股份
|
| Abich Financial Wealth Management LLC |
$69306 |
5096 |
0.00% |
股份
|
| HM PAYSON & CO |
$52411 |
1700 |
0.00% |
股份
|
| Arax Advisory Partners |
$41097 |
1333 |
0.00% |
股份
|
| OSAIC HOLDINGS, INC. |
$34129 |
1107 |
0.00% |
股份
|
| Salomon & Ludwin, LLC |
$28804 |
996 |
0.00% |
股份
|
| Optiver Holding B.V. |
$25836 |
838 |
0.00% |
股份
|
| Kemnay Advisory Services Inc. |
$24664 |
800 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$19546 |
634 |
0.00% |
股份
|
| T. Rowe Price Investment Management, Inc. |
$18176 |
589546 |
0.00% |
股份
|
| UMB Bank, n.a. |
$17573 |
570 |
0.00% |
股份
|
| US BANCORP \DE\ |
$14151 |
459 |
0.00% |
股份
|
| LOS ANGELES CAPITAL MANAGEMENT LLC |
$10698 |
347 |
0.00% |
股份
|
| SMA Capital LLC |
$10421 |
338 |
0.00% |
股份
|
| Activest Wealth Management |
$9341 |
303 |
0.00% |
股份
|
| Versant Capital Management, Inc |
$9247 |
358 |
0.00% |
股份
|
| MassMutual Private Wealth & Trust, FSB |
$8293 |
269 |
0.00% |
股份
|
| Truvestments Capital LLC |
$6074 |
197 |
0.00% |
股份
|
| Smartleaf Asset Management LLC |
$5781 |
186 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$5487 |
178 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$4532 |
147 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$4257 |
138 |
0.00% |
股份
|
| Keating Financial Advisory Services, Inc. |
$4162 |
135 |
0.00% |
股份
|
| Quantbot Technologies LP |
$3854 |
125 |
0.00% |
股份
|
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM |
$2850 |
92431 |
0.00% |
股份
|
| NATIONAL BANK OF CANADA /FI/ |
$2804 |
91 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$2751 |
89202 |
0.00% |
股份
|
| Parkside Financial Bank & Trust |
$2621 |
85 |
0.00% |
股份
|
| Thrivent Financial for Lutherans |
$2427 |
78718 |
0.00% |
股份
|
| CANADA LIFE ASSURANCE Co |
$2174 |
70518 |
0.00% |
股份
|
| JONES FINANCIAL COMPANIES LLLP |
$2077 |
67 |
0.00% |
股份
|
| Allworth Financial LP |
$1881 |
61 |
0.00% |
股份
|
| Fortitude Family Office, LLC |
$1387 |
45 |
0.00% |
股份
|
| Global Retirement Partners, LLC |
$1172 |
38 |
0.00% |
股份
|
| FARMERS & MERCHANTS INVESTMENTS INC |
$1172 |
38 |
0.00% |
股份
|
| SG Americas Securities, LLC |
$1164 |
37765 |
0.00% |
股份
|
| Quarry LP |
$925 |
30 |
0.00% |
股份
|
| State of Alaska, Department of Revenue |
$881 |
28580 |
0.00% |
股份
|
| Penserra Capital Management LLC |
$830 |
26929 |
0.00% |
股份
|
| Essential Partners LLC |
$771 |
25 |
0.00% |
股份
|
| AMALGAMATED BANK |
$721 |
23384 |
0.00% |
股份
|
| Larson Financial Group LLC |
$709 |
23 |
0.00% |
股份
|
| Cedar Mountain Advisors, LLC |
$678 |
22 |
0.00% |
股份
|
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY |
$646 |
20950 |
0.00% |
股份
|
| Plante Moran Financial Advisors, LLC |
$617 |
20 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$617 |
20 |
0.00% |
股份
|
| IFP Advisors, Inc |
$555 |
18 |
0.00% |
股份
|
| GILPIN WEALTH MANAGEMENT, LLC |
$432 |
14 |
0.00% |
股份
|
| NATIXIS ADVISORS, LLC |
$378 |
12267 |
0.00% |
股份
|
| ACADIAN ASSET MANAGEMENT LLC |
$372 |
12107 |
0.00% |
股份
|
| Silver Grove Financial Group, Inc. |
$277 |
9 |
0.00% |
股份
|
| Ankerstar Wealth, LLC |
$247 |
8 |
0.00% |
股份
|
| Clearstead Advisors, LLC |
$155 |
5 |
0.00% |
股份
|
| Davis Capital Management |
$123 |
4 |
0.00% |
股份
|
| Abound Wealth Management |
$108 |
5 |
0.00% |
股份
|
| Lindbrook Capital, LLC |
$102 |
13 |
0.00% |
股份
|
| KBC Group NV |
$72 |
2334 |
0.00% |
股份
|
| HANTZ FINANCIAL SERVICES, INC. |
$61 |
1990 |
0.00% |
股份
|
| Pacer Advisors, Inc. |
$37 |
1198 |
0.00% |
股份
|
| Hughes Financial Services, LLC |
$31 |
1 |
0.00% |
股份
|
| TFC Financial Management, Inc. |
$31 |
1 |
0.00% |
股份
|
| Inspire Investing, LLC |
$26 |
1 |
0.00% |
股份
|
| BESSEMER GROUP INC |
$19 |
629 |
0.00% |
股份
|
| Covestor Ltd |
$1 |
25 |
0.00% |
股份
|
| Avion Wealth |
$1 |
64 |
0.00% |
股份
|
| Capital Advisors, Ltd. LLC |
$0 |
1 |
0.00% |
股份
|
| Evolution Advisers, Inc. |
$0 |
18 |
0.00% |
股份
|