TSHA Taysha Gene Therapies, Inc. - Common Stock
TSHA Aktien-Snapshot Kurs, Marktkapitalisierung, P/E, EPS, ROE, Schulden/Eigenkapital, 52-Wochen-Spanne
TSHA Aktienkurs-Chart Täglich OHLCV mit technischen Indikatoren — Schwenken, Zoom und Ansicht anpassen
10-Jahres-Performance Umsatz-, Nettoergebnis-, Margen- und EPS-Trends
Bewertung P/E-, P/S-, P/B-, EV/EBITDA-Verhältnisse — ist die Aktie teuer oder günstig?
Rentabilität Brutto-, Betriebs- und Nettomargen; ROE, ROA, ROIC
Finanzielle Gesundheit Verschuldung, Liquidität, Solvenz — Bilanzstärke
Wachstum Umsatz-, EPS- und Nettoergebniswachstum: YoY, 3-Jahres-CAGR, 5-Jahres-CAGR
Kapitaleffizienz Umsatz pro Vermögenswert, Lagerumschlag, Forderungsumschlag
TSHA Analysten-Konsens Bullische und bärische Analystenmeinungen, 12-Monats-Kursziel, Aufwärtspotenzial
- Starker Kauf 6 33,3%
- Kauf 11 61,1%
- Halten 1 5,6%
- Verkauf 0 0,0%
- Starker Verkauf 0 0,0%
12-Monats-Kursziel
12 Analysten · 2026-08-16Ergebnisverlauf EPS Ist vs. Schätzung, Überraschung %, Beat-Rate, nächstes Ergebnisdatum
| Zeitraum | EPS Actual | EPS est. | Überraschung |
|---|---|---|---|
| 30. Juni 2026 | $-0.13 | $-0.12 | -0.01% |
| 31. März 2026 | $-0.12 | $-0.10 | -0.02% |
| 31. Dezember 2025 | $-0.08 | $-0.10 | 0.02% |
| 30. September 2025 | $-0.09 | $-0.09 | 0.00% |
| 30. Juni 2025 | $-0.09 | $-0.08 | -0.01% |
| 31. März 2025 | $-0.08 | $-0.09 | 0.01% |
| 31. Dezember 2024 | $-0.07 | $-0.08 | 0.01% |
Peer-Vergleich (GICS-Subbranche) Wichtige Kennzahlen im Vergleich zu Branchenkollegen
| Ticker | Marktkapitalisierung | P/E | Umsatz Vj. | Nettomarge | ROE | Bruttogewinnmarge |
|---|---|---|---|---|---|---|
| TSHA | $1.57B | -16.2 | 17.3% | -1115.3% | -44.0% | — |
| ADMA | $4.34B | 30.4 | 19.6% | 28.8% | 33.6% | 57.4% |
| VRDN | $3.17B | -7.7 | 23359.9% | -483.6% | -55.4% | — |
| STOK | $1.87B | -264.5 | 404.5% | -3.7% | -2.0% | — |
| ZBIO | $1.98B | -4.3 | 100.0% | -3777.4% | -156.8% | — |
| AGIO | $1.59B | -3.8 | 48.0% | -764.0% | -32.2% | — |
| GENB | — | — | — | — | — | — |
| DMRA | — | — | 38.3% | -17981.1% | -167.0% | — |
| SRPT | $2.26B | -3.0 | 15.6% | -32.5% | -57.1% | — |
| SNDX | $1.84B | -6.4 | 627.8% | -165.6% | -257.1% | — |
| ANAB | — | -105.4 | 157.0% | — | — | — |
Vollständige Fundamentaldaten Alle Kennzahlen nach Jahr — Gewinn- und Verlustrechnung, Bilanz, Cashflow
Gewinn- und Verlustrechnung 15
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue | $10M | $8M | $15M | $3M | |
| R&D Expense | $86M | $66M | $57M | $91M | |
| SG&A Expense | $34M | $29M | $30M | $37M | |
| Operating Expenses | $120M | $100M | $88M | $165M | |
| Operating Income | $-110M | $-91M | $-72M | $-162M | |
| Interest Expense | · | · | $5M | $4M | |
| Interest Income | $9M | $7M | $4M | · | |
| Other Non-op | $-291.0K | $-110.0K | $-47.0K | $-18.0K | |
| Income Tax | $0 | $0 | $0 | $0 | |
| Net Income | $-109M | $-89M | $-112M | $-166M | |
| EPS (Basic) | $-0.34 | $-0.36 | $-0.96 | $-3.78 | |
| EPS (Diluted) | $-0.34 | $-0.36 | $-0.96 | $-3.78 | |
| Shares (Basic) | 319,711,972 | 250,134,421 | 116,121,482 | 43,952,015 | |
| Shares (Diluted) | 319,711,972 | 250,134,421 | 116,121,482 | 43,952,015 | |
| EBITDA | $-110M | $-91M | $-72M | · |
Bilanz 23
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $320M | $139M | $144M | $88M | |
| Prepaid Expense | $4M | $3M | $3M | $9M | |
| Other Current Assets | $802.0K | $308.0K | $292.0K | $466.0K | |
| Current Assets | $325M | $142M | $150M | $96M | |
| PP&E (Net) | $7M | $7M | $11M | $15M | |
| PP&E (Gross) | $11M | $11M | $14M | $17M | |
| Accum. Depreciation | $5M | $4M | $3M | $2M | |
| Other Non-current Assets | $183.0K | $217.0K | $304.0K | $1M | |
| Total Assets | $343M | $160M | $173M | $126M | |
| Accounts Payable | $6M | $4M | $6M | $11M | |
| Current Liabilities | $27M | $26M | $37M | $63M | |
| Capital Leases | $18M | $17M | $19M | $20M | |
| Other Non-current Liabilities | $2M | $1M | $2M | $4M | |
| Total Liabilities | $96M | $89M | $98M | $125M | |
| Long-term Debt | · | · | · | $38M | |
| Total Debt | $50M | $44M | $41M | · | |
| Common Stock | $3.0K | $2.0K | $2.0K | $1.0K | |
| Paid-in Capital | $958M | $678M | $588M | $402M | |
| Retained Earnings | $-711M | $-602M | $-513M | $-401M | |
| AOCI | $-192.0K | $-4M | · | · | |
| Stockholders' Equity | $247M | $72M | $75M | $949.0K | |
| Liabilities + Equity | $343M | $160M | $173M | $126M | |
| Shares Outstanding | 285,051,648 | 204,943,306 | 186,960,193 | 63,207,507 |
Cashflow 8
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Stock-based Comp | $13M | $13M | $8M | $18M | |
| Operating Cash Flow | $-93M | $-81M | $-73M | $-88M | |
| CapEx | $738.0K | $374.0K | $4M | $21M | |
| Investing Cash Flow | $-604.0K | $-363.0K | $-7M | $-25M | |
| Stock Issued | · | · | $500.0K | · | |
| Financing Cash Flow | $275M | $77M | $136M | $52M | |
| Net Change in Cash | $181M | $-5M | $56M | $-61M | |
| Free Cash Flow | $-94M | $-82M | $-77M | · |
Rentabilität 5
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Operating Margin | -1130.7% | -1097.5% | -468.8% | · | |
| Net Margin | -1115.3% | -1071.6% | -722.1% | · | |
| EBITDA Margin | -1130.7% | -1097.5% | -468.8% | · | |
| ROA | -43.3% | -53.6% | -74.6% | · | |
| ROE | -44.0% | -111.4% | -864.1% | · |
Liquidität & Solvenz 5
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 12.2 | 5.4 | 4.1 | · | |
| Quick Ratio | 12.0 | 5.3 | 3.9 | · | |
| Debt / Equity | 0.2 | 0.6 | 0.5 | · | |
| LT Debt / Equity | 0.2 | 0.6 | 0.5 | · | |
| Interest Coverage | · | · | -14.5 | · |
Effizienz 1
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.1 | 0.1 | · |
Wachstumsraten 2
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue YoY | 17.3% | -46.1% | 517.6% | · | |
| Revenue CAGR 3Y | 57.5% | · | · | · |
Bewertung (TTM) 14
| Kennzahl | Trend | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue TTM | $10M | $8M | $15M | $3M | |
| Net Income TTM | $-109M | $-89M | $-112M | $-166M | |
| Market Cap | $1.57B | $355M | $331M | · | |
| Enterprise Value | $1.30B | $259M | $227M | · | |
| P/E | -16.2 | -4.8 | -1.8 | -0.6 | |
| P/S | 160.4 | 42.5 | 21.4 | · | |
| P/B | 6.3 | 5.0 | 4.4 | · | |
| P / Tangible Book | 6.3 | 5.0 | 4.4 | 150.5 | |
| P / Cash Flow | -16.8 | -4.4 | -4.5 | · | |
| P / FCF | -16.7 | -4.3 | -4.3 | · | |
| EV / EBITDA | -11.7 | -2.8 | -3.1 | · | |
| EV / FCF | -13.8 | -3.2 | -3.0 | · | |
| EV / Revenue | 132.8 | 31.1 | 14.7 | · | |
| Earnings Yield | -6.2% | -20.8% | -54.2% | -167.3% |
Gewinn- und Verlustrechnung 15
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $5M | $0 | $2M | $2M | $2M | $2M | $1M | $3M | $4M | $5M | $2M | $5M | |
| R&D Expense | $39M | $34M | $25M | $26M | $20M | $16M | $15M | $15M | $15M | $21M | $13M | $12M | $20M | $13M | |
| SG&A Expense | $12M | $10M | $9M | $8M | $9M | $8M | $7M | $8M | $7M | $7M | $7M | $9M | $6M | $9M | |
| Operating Expenses | $47M | $43M | $34M | $34M | $29M | $24M | $22M | $28M | $22M | $28M | $20M | $21M | $26M | $21M | |
| Operating Income | $-47M | $-43M | $-28M | $-34M | $-27M | $-21M | $-20M | $-26M | $-21M | $-24M | $-16M | $-16M | $-23M | $-17M | |
| Interest Expense | · | · | · | · | · | · | · | · | $27.0K | $29.0K | · | $1M | $1M | $1M | |
| Interest Income | $2M | $3M | $3M | $3M | $2M | $1M | $2M | $2M | $1M | $2M | $2M | $1M | · | · | |
| Other Non-op | $-88.0K | $-31.0K | $-30.0K | $-37.0K | $-237.0K | $13.0K | $-66.0K | $-81.0K | $42.0K | $-5.0K | $-23.0K | $-19.0K | $3.0K | $-8.0K | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | · | $0 | $0 | $0 | |
| Net Income | $-47M | $-42M | $-28M | $-33M | $-27M | $-22M | $-19M | $-26M | $-21M | $-24M | $48M | $-117M | $-25M | $-18M | |
| EPS (Basic) | $-0.13 | $-0.12 | $-0.08 | $-0.09 | $-0.09 | $-0.08 | $-0.07 | $-0.10 | $-0.09 | $-0.10 | $0.63 | $-0.93 | $-0.38 | $-0.28 | |
| EPS (Diluted) | $-0.13 | $-0.12 | $-0.08 | $-0.09 | $-0.09 | $-0.08 | $-0.07 | $-0.10 | $-0.09 | $-0.10 | $0.63 | $-0.93 | $-0.38 | $-0.28 | |
| Shares (Basic) | 369,044,040 | 366,632,827 | -600,892,861 | 353,309,524 | 297,988,978 | 269,306,331 | -481,760,521 | 267,824,045 | 232,821,553 | 231,249,344 | -137,084,753 | 125,700,799 | 64,244,531 | 63,260,905 | |
| Shares (Diluted) | 369,044,040 | 366,632,827 | -600,892,861 | 353,309,524 | 297,988,978 | 269,306,331 | -481,760,521 | 267,824,045 | 232,821,553 | 231,249,344 | -137,084,753 | 125,700,799 | 64,244,531 | 63,260,905 | |
| EBITDA | $-47M | $-43M | · | $-34M | $-27M | $-21M | · | $-26M | $-21M | $-24M | · | $-16M | $-23M | $-17M |
Bilanz 23
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $455M | $277M | $320M | $297M | $313M | $117M | $139M | $158M | $173M | $124M | $144M | $164M | $45M | $63M | |
| Prepaid Expense | $6M | $5M | $4M | $2M | $3M | $4M | $3M | $3M | $3M | $4M | $3M | $6M | $9M | $9M | |
| Other Current Assets | $851.0K | $1M | $802.0K | $456.0K | $657.0K | $536.0K | $308.0K | $465.0K | $206.0K | $149.0K | $292.0K | $404.0K | $510.0K | $532.0K | |
| Current Assets | $461M | $282M | $325M | $300M | $316M | $121M | $142M | $162M | $178M | $131M | $150M | $172M | $54M | $72M | |
| PP&E (Net) | $2M | $6M | $7M | $7M | $7M | $7M | $7M | $8M | $11M | $11M | $11M | $11M | $14M | $15M | |
| PP&E (Gross) | $8M | $11M | $11M | $11M | $11M | $11M | $11M | $12M | $14M | $14M | $14M | $14M | $16M | $17M | |
| Accum. Depreciation | $5M | $5M | $5M | $4M | $4M | $4M | $4M | $4M | $4M | $3M | $3M | $3M | $2M | $2M | |
| Other Non-current Assets | $106.0K | $181.0K | $183.0K | $184.0K | $186.0K | $188.0K | $217.0K | $220.0K | $288.0K | $304.0K | $304.0K | $304.0K | $304.0K | $1M | |
| Total Assets | $470M | $300M | $343M | $317M | $333M | $138M | $160M | $180M | $200M | $153M | $173M | $196M | $82M | $102M | |
| Accounts Payable | $9M | $5M | $6M | $5M | $8M | $4M | $4M | $5M | $9M | $10M | $6M | $8M | $11M | $9M | |
| Current Liabilities | $26M | $20M | $27M | $29M | $25M | $23M | $26M | $29M | $34M | $39M | $37M | $180M | $51M | $54M | |
| Capital Leases | $6M | $18M | $18M | $17M | $17M | $17M | $17M | $18M | $18M | $18M | $19M | $19M | $20M | $20M | |
| Other Non-current Liabilities | $2M | $2M | $2M | $2M | $1M | $1M | $1M | $1M | $1M | $2M | $2M | $4M | $4M | $4M | |
| Total Liabilities | $83M | $88M | $96M | $98M | $85M | $83M | $89M | $91M | $92M | $99M | $98M | $245M | $119M | $117M | |
| Long-term Debt | · | · | · | · | · | · | · | · | · | · | · | · | $38M | $38M | |
| Total Debt | $49M | $49M | · | $51M | $41M | $42M | · | $43M | $38M | $41M | · | $39M | $38M | $38M | |
| Common Stock | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $1.0K | $1.0K | |
| Paid-in Capital | $1.19B | $965M | $958M | $904M | $900M | $681M | $678M | $675M | $664M | $591M | $588M | $512M | $407M | $404M | |
| Retained Earnings | $-800M | $-754M | $-711M | $-683M | $-651M | $-624M | $-602M | $-584M | $-558M | $-537M | $-513M | $-561M | $-444M | $-419M | |
| AOCI | $769.0K | $985.0K | $-192.0K | $-1M | $-699.0K | $-2M | $-4M | $-2M | $2M | $-251.0K | · | · | · | · | |
| Stockholders' Equity | $387M | $212M | $247M | $219M | $249M | $55M | $72M | $89M | $109M | $54M | $75M | $-49M | $-37M | $-15M | |
| Liabilities + Equity | $470M | $300M | $343M | $317M | $333M | $138M | $160M | $180M | $200M | $153M | $173M | $196M | $82M | $102M | |
| Shares Outstanding | 325,302,280 | 287,276,885 | 285,051,648 | 273,915,373 | 272,730,060 | 205,054,570 | 204,943,306 | 204,943,306 | 201,381,450 | 187,018,275 | 186,960,193 | 186,960,193 | 64,432,637 | 63,473,349 |
Cashflow 8
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $6M | $6M | $4M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $2M | $2M | $2M | $2M | |
| Operating Cash Flow | $-40M | $-41M | $-27M | $-24M | $-20M | $-22M | $-18M | $-22M | $-22M | $-20M | $-16M | $-18M | $-19M | $-20M | |
| CapEx | $-1.0K | $24.0K | $250.0K | $108.0K | $2.0K | $378.0K | $-2.0K | $35.0K | $201.0K | $140.0K | $17.0K | $0 | $-48.0K | $4M | |
| Investing Cash Flow | $1.0K | $-3M | $-247.0K | $-48.0K | $62.0K | $-371.0K | $13.0K | $-35.0K | $-201.0K | $-140.0K | $-10.0K | $-3M | $48.0K | $-4M | |
| Stock Issued | · | · | · | · | · | · | · | · | · | · | $0 | · | · | · | |
| Financing Cash Flow | $217M | $711.0K | $50M | $9M | $216M | $-52.0K | $-357.0K | $7M | $70M | $-22.0K | $-4M | $141M | $377.0K | $-370.0K | |
| Net Change in Cash | $176M | $-43M | $23M | $-15M | $196M | $-22M | $-19M | $-15M | $49M | $-20M | $-20M | $119M | $-18M | $-24M | |
| Free Cash Flow | · | $-41M | · | · | · | · | · | · | · | $-20M | · | · | · | $-24M |
Rentabilität 5
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | -1347.1% | -930.5% | · | -1448.4% | -1915.4% | -713.3% | · | -342.4% | -976.4% | -351.9% | |
| Net Margin | · | · | · | · | -1353.6% | -935.2% | · | -1427.5% | -1882.0% | -705.4% | · | -2467.1% | -1027.1% | -374.5% | |
| EBITDA Margin | · | · | · | · | -1347.1% | -930.5% | · | -1448.4% | -1915.4% | -713.3% | · | -342.4% | -976.4% | -351.9% | |
| ROA | -11.6% | -19.3% | · | -13.2% | -10.1% | -14.8% | · | -13.6% | -14.8% | -18.9% | · | -76.2% | -22.0% | -13.2% | |
| ROE | -14.7% | -31.8% | · | -21.3% | -15.0% | -39.5% | · | -128.6% | -58.3% | -123.7% | · | 616.4% | 1117.1% | -98.5% |
Liquidität & Solvenz 5
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 17.8 | 14.0 | · | 10.5 | 12.5 | 5.4 | · | 5.5 | 5.2 | 3.4 | · | 1.0 | 1.1 | 1.3 | |
| Quick Ratio | 17.5 | 13.8 | · | 10.4 | 12.3 | 5.2 | · | 5.4 | 5.1 | 3.2 | · | 0.9 | 0.9 | 1.2 | |
| Debt / Equity | 0.1 | 0.2 | · | 0.2 | 0.2 | 0.8 | · | 0.5 | 0.3 | 0.8 | · | -0.8 | -1.0 | -2.6 | |
| LT Debt / Equity | 0.1 | 0.2 | · | 0.2 | 0.2 | 0.8 | · | 0.5 | 0.3 | 0.8 | · | -0.8 | -1.0 | -2.6 | |
| Interest Coverage | · | · | · | · | · | · | · | · | -788.9 | -839.0 | · | -11.0 | -16.2 | -12.1 |
Effizienz 1
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 |
Bewertung (TTM) 14
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $2M | $4M | · | $6M | $7M | $9M | · | $11M | $12M | $15M | · | · | · | · | |
| Net Income TTM | $-149M | $-124M | · | $-107M | $-95M | $-92M | · | $-188M | $-187M | $-183M | · | $-186M | $-103M | $-129M | |
| Market Cap | $2.22B | $1.28B | · | $896M | $630M | $285M | · | $412M | $451M | $537M | · | $591M | $43M | $51M | |
| Enterprise Value | $1.81B | $1.06B | · | $649M | $358M | $211M | · | $297M | $316M | $453M | · | $465M | $36M | $25M | |
| P/E | -15.8 | -11.8 | · | -9.1 | -6.4 | -3.8 | · | -1.6 | -1.5 | -1.7 | · | -1.4 | -0.3 | -0.3 | |
| P/S | 1115.5 | 299.5 | · | 147.4 | 87.6 | 33.1 | · | 37.3 | 38.7 | 35.2 | · | · | · | · | |
| P/B | 5.7 | 6.1 | · | 4.1 | 2.5 | 5.2 | · | 4.6 | 4.1 | 10.0 | · | -12.0 | -1.1 | -3.4 | |
| P / Tangible Book | 5.7 | 6.1 | · | 4.1 | 2.5 | 5.2 | · | 4.6 | 4.1 | 10.0 | · | · | · | · | |
| P / Cash Flow | · | -31.4 | · | · | · | -12.9 | · | · | · | -27.1 | · | · | · | -2.5 | |
| P / FCF | · | -31.4 | · | · | · | · | · | · | · | -26.9 | · | · | · | -2.1 | |
| EV / EBITDA | -38.2 | -24.3 | · | -19.1 | -13.4 | -9.8 | · | -11.5 | -14.8 | -18.6 | · | -28.6 | -1.5 | -1.5 | |
| EV / FCF | · | -25.8 | · | · | · | · | · | · | · | -22.7 | · | · | · | -1.1 | |
| EV / Revenue | 911.0 | 246.4 | · | 106.8 | 49.8 | 24.5 | · | 26.9 | 27.1 | 29.7 | · | · | · | · | |
| Earnings Yield | -6.3% | -8.5% | · | -11.0% | -15.6% | -26.6% | · | -60.7% | -67.0% | -58.9% | · | -70.9% | -326.8% | -388.5% |
Finanzberichte Gewinn- und Verlustrechnung, Bilanz, Cashflow — jährlich, letzte 5 Jahre
Gewinn- und Verlustrechnung
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Umsatz | $10M | $8M | $15M | $3M | — |
| Betriebsgewinnmarge % | -1130.7% | -1097.5% | -468.8% | — | — |
| Nettoergebnis | $-109M | $-89M | $-112M | $-166M | $-175M |
| Verwässerte EPS | $-0.34 | $-0.36 | $-0.96 | $-3.78 | $-4.64 |
Bilanz
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Fremdkapital / Eigenkapital | 0.2 | 0.6 | 0.5 | — | 0.4 |
| Liquiditätsgrad | 12.2 | 5.4 | 4.1 | — | 3.1 |
| Quick Ratio | 12.0 | 5.3 | 3.9 | — | 2.9 |
Cashflow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Freier Cashflow | $-94M | $-82M | $-77M | — | $-132M |
Neueste Nachrichten Aktuelle Schlagzeilen über dieses Unternehmen
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Institutionelle Eigentümer (13F) 224 Einreicher · $1.7B gesamt · Stand 30. Juni 2026
Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.
| Neue Positionen | Geschlossene Positionen | Erhöht | Abgenommen | Nettoveränderung der Aktien |
|---|---|---|---|---|
| 48 (+20 vs. Vorquartal) | 23 (-7 vs. Vorquartal) | 90 (+26 vs. Vorquartal) | 42 (-13 vs. Vorquartal) | +44.7M |
Verglichen mit Q1 2026. SEC-Formular 13F-Einreichungen sind innerhalb von 45 Tagen nach Quartalsende fällig, zuzüglich einer kurzen Pufferzeit für verspätete Einreicher — Quartale, die noch in diesem Fenster liegen, werden zugunsten des letzten vollständig berichteten Paares übersprungen.
| Institution | Wert | Aktien | % der verfolgten 13F | Typ |
|---|---|---|---|---|
| Avoro Capital Advisors LLC | $162.683.327 | 23.888.888 | 9,61% | Aktien |
| RA CAPITAL MANAGEMENT, L.P. | $160.413.963 | 23.555.648 | 9,48% | Aktien |
| Vestal Point Capital, LP | $132.216.150 | 19.415.000 | 7,81% | Aktien |
| GOLDMAN SACHS GROUP INC | $92.490.887 | 13.581.628 | 5,46% | Aktien |
| RTW INVESTMENTS, LP | $92.345.357 | 13.560.258 | 5,46% | Aktien |
| VANGUARD CAPITAL MANAGEMENT LLC | $84.979.232 | 12.478.595 | 5,02% | Aktien |
| STATE STREET CORP | $77.783.275 | 11.421.920 | 4,59% | Aktien |
| Siren, L.L.C. | $67.055.203 | 9.846.579 | 3,96% | Aktien |
| Octagon Capital Advisors LP | $66.010.992 | 9.693.244 | 3,90% | Aktien |
| VANGUARD GROUP INC | $63.339.386 | 11.516.252 | 3,74% | Aktien |
| FMR LLC | $53.647.634 | 7.877.773 | 3,17% | Aktien |
| GEODE CAPITAL MANAGEMENT, LLC | $38.279.203 | 5.619.701 | 2,26% | Aktien |
| Polar Capital Holdings Plc | $34.847.676 | 5.117.133 | 2,06% | Aktien |
| MPM BIOIMPACT LLC | $30.645.000 | 4.500.000 | 1,81% | Aktien |
| BAKER BROS. ADVISORS LP | $27.272.388 | 4.004.756 | 1,61% | Aktien |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $26.460.262 | 3.885.501 | 1,56% | Aktien |
| GordonMD Global Investments LP | $24.501.508 | 723.185 | 1,45% | Aktien |
| Casdin Capital, LLC | $22.132.500 | 3.250.000 | 1,31% | Aktien |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $21.383.461 | 3.140.009 | 1,26% | Aktien |
| ADAR1 Capital Management, LLC | $20.705.573 | 3.040.466 | 1,22% | Aktien |
| Pictet Asset Management Holding SA | $18.868.474 | 2.770.701 | 1,11% | Aktien |
| Aberdeen Group plc | $15.847.905 | 2.327.152 | 0,94% | Aktien |
| WELLINGTON MANAGEMENT GROUP LLP | $15.761.752 | 2.314.501 | 0,93% | Aktien |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $15.322.500 | 2.250.000 | 0,91% | Aktien |
| NORGES BANK | $15.210.816 | 2.233.600 | 0,90% | Aktien |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $14.986.733 | 2.200.695 | 0,89% | Aktien |
| MILLENNIUM MANAGEMENT LLC | $14.483.767 | 2.126.838 | 0,86% | Aktien |
| ORBIMED ADVISORS LLC | $13.620.000 | 2.000.000 | 0,80% | Aktien |
| RICE HALL JAMES & ASSOCIATES, LLC | $13.567.079 | 1.992.229 | 0,80% | Aktien |
| VANGUARD FIDUCIARY TRUST CO | $12.914.988 | 1.896.474 | 0,76% | Aktien |
| B Group, Inc. | $12.261.786 | 1.800.556 | 0,72% | Aktien |
| TYBOURNE CAPITAL MANAGEMENT (HK) LTD | $12.099.000 | 3.700.000 | 0,71% | Aktien |
| Affinity Asset Advisors, LLC | $11.917.500 | 1.750.000 | 0,70% | Aktien |
| BARCLAYS PLC | $11.020.670 | 1.618.307 | 0,65% | Aktien |
| HEIGHTS CAPITAL MANAGEMENT, INC | $10.215.000 | 1.500.000 | 0,60% | Aktien |
| Seven Fleet Capital Management LP | $9.940.323 | 1.504.400 | 0,59% | Aktien |
| Palo Alto Investors LP | $9.475.311 | 1.391.382 | 0,56% | Aktien |
| Granahan Investment Management, LLC | $8.888.255 | 1.305.177 | 0,53% | Aktien |
| BANK OF AMERICA CORP /DE/ | $8.103.178 | 1.189.894 | 0,48% | Aktien |
| CITADEL ADVISORS LLC | $7.471.292 | 1.097.106 | 0,44% | Aktien |
| Quantum Private Wealth, LLC | $5.529.903 | 812.027 | 0,33% | Aktien |
| FIRST TRUST ADVISORS LP | $5.387.860 | 791.169 | 0,32% | Aktien |
| Sands Capital Alternatives, LLC | $4.936.385 | 724.873 | 0,29% | Aktien |
| D. E. Shaw & Co., Inc. | $4.871.997 | 715.418 | 0,29% | Aktien |
| BNP PARIBAS FINANCIAL MARKETS | $4.358.638 | 640.035 | 0,26% | Aktien |
| PANAGORA ASSET MANAGEMENT INC | $4.020.535 | 590.387 | 0,24% | Aktien |
| AFFINITY WEALTH MANAGEMENT LLC | $3.928.062 | 576.808 | 0,23% | Aktien |
| Squarepoint Ops LLC | $3.876.722 | 569.269 | 0,23% | Aktien |
| ACUTA CAPITAL PARTNERS, LLC | $3.825.912 | 561.808 | 0,23% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3.799.980 | 558.000 | 0,22% | Kaufoption |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $3.765.930 | 553.000 | 0,22% | Aktien |
| DIADEMA PARTNERS LP | $3.559.035 | 522.619 | 0,21% | Aktien |
| Woodline Partners LP | $3.499.169 | 513.828 | 0,21% | Aktien |
| Holocene Advisors, LP | $3.473.100 | 510.000 | 0,21% | Aktien |
| Ghisallo Capital Management LLC | $3.439.050 | 505.000 | 0,20% | Aktien |
| Burkehill Global Management, LP | $3.405.000 | 500.000 | 0,20% | Aktien |
| POLEN CAPITAL MANAGEMENT LLC | $3.331.581 | 489.219 | 0,20% | Aktien |
| Trexquant Investment LP | $2.584.919 | 379.577 | 0,15% | Aktien |
| Swiss National Bank | $2.512.890 | 369.000 | 0,15% | Aktien |
| MOORE CAPITAL MANAGEMENT, LP | $2.440.527 | 358.374 | 0,14% | Aktien |
| DIMENSIONAL FUND ADVISORS LP | $2.371.603 | 348.253 | 0,14% | Aktien |
| Jefferies Financial Group Inc. | $2.239.128 | 328.800 | 0,13% | Aktien |
| RHUMBLINE ADVISERS | $2.042.820 | 299.975 | 0,12% | Aktien |
| CITIGROUP INC | $1.995.800 | 293.069 | 0,12% | Aktien |
| ALPS ADVISORS INC | $1.978.598 | 290.543 | 0,12% | Aktien |
| Ensign Peak Advisors, Inc | $1.790.322 | 262.896 | 0,11% | Aktien |
| Qube Research & Technologies Ltd | $1.767.910 | 259.605 | 0,10% | Aktien |
| SPHERA FUNDS MANAGEMENT LTD. | $1.702.500 | 250.000 | 0,10% | Aktien |
| Bank of New York Mellon Corp | $1.660.258 | 243.797 | 0,10% | Aktien |
| TWO SIGMA INVESTMENTS, LP | $1.598.416 | 234.716 | 0,09% | Aktien |
| WELLS FARGO & COMPANY/MN | $1.489.565 | 218.732 | 0,09% | Aktien |
| ORACLE INVESTMENT MANAGEMENT INC | $1.457.500 | 265.000 | 0,09% | Aktien |
| BlackRock, Inc. | $1.411.468 | 207.264 | 0,08% | Aktien |
| Monashee Investment Management LLC | $1.362.000 | 200.000 | 0,08% | Aktien |
| Privium Fund Management B.V. | $1.354.509 | 198.900 | 0,08% | Aktien |
| VICTORY CAPITAL MANAGEMENT INC | $1.345.506 | 197.578 | 0,08% | Aktien |
| Chicago Partners Investment Group LLC | $1.296.283 | 222.347 | 0,08% | Aktien |
| Balyasny Asset Management L.P. | $1.289.351 | 189.332 | 0,08% | Aktien |
| STATE OF WISCONSIN INVESTMENT BOARD | $1.205.976 | 177.089 | 0,07% | Aktien |
| MORGAN STANLEY | $1.204.212 | 176.830 | 0,07% | Aktien |
| ALLIANCEBERNSTEIN L.P. | $1.107.130 | 247.680 | 0,07% | Aktien |
| WEXFORD CAPITAL LP | $1.094.054 | 160.654 | 0,06% | Aktien |
| JANE STREET GROUP, LLC | $1.054.045 | 154.779 | 0,06% | Aktien |
| Rafferty Asset Management, LLC | $1.053.548 | 154.706 | 0,06% | Aktien |
| Palumbo Wealth Management LLC | $1.015.869 | 149.173 | 0,06% | Aktien |
| MetLife Investment Management, LLC | $959.161 | 140.846 | 0,06% | Aktien |
| Vanguard Global Advisers, LLC | $911.321 | 133.821 | 0,05% | Aktien |
| Persistent Asset Partners Ltd | $908.529 | 133.411 | 0,05% | Aktien |
| VANGUARD ASSET MANAGEMENT, Ltd | $903.101 | 132.614 | 0,05% | Aktien |
| Mariner, LLC | $793.923 | 116.582 | 0,05% | Aktien |
| CITADEL ADVISORS LLC | $783.150 | 115.000 | 0,05% | Kaufoption |
| TWO SIGMA ADVISERS, LP | $767.696 | 139.581 | 0,05% | Aktien |
| Aquatic Capital Management LLC | $736.896 | 108.208 | 0,04% | Aktien |
| Engineers Gate Manager LP | $709.139 | 104.132 | 0,04% | Aktien |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $708.887 | 104.095 | 0,04% | Aktien |
| XTX Topco Ltd | $689.138 | 101.195 | 0,04% | Aktien |
| PRELUDE CAPITAL MANAGEMENT, LLC | $669.736 | 98.346 | 0,04% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $663.294 | 97.400 | 0,04% | Verkaufsoption |
| Invesco Ltd. | $650.055 | 95.456 | 0,04% | Aktien |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $612.091 | 136.933 | 0,04% | Aktien |
Unternehmensinsider 11 Insider · 4 Führungskräfte · 7 Direktoren
| Insider | Rolle | Letzte Aktivität | Gehaltene Aktien | Käufe 12m | Verkäufe 12m | Netto 12m |
|---|---|---|---|---|---|---|
| Sean P. Nolan | Chief Executive Officer | 2. Januar 2024 A | 1.185.858 | 0 | 0 | $0 |
| Kamran Alam | Chief Financial Officer | 2. Januar 2024 A | 842.225 | 0 | 0 | $0 |
| Sukumar Nagendran | President and Head of R&D | 2. Januar 2024 A | 897.843 | 0 | 0 | $0 |
| Suyash Prasad | CMO and Head of R&D | 6. Juli 2022 S | 530.589 | 0 | 0 | $0 |
| Alison S Long | Direktor | 1. November 2023 A | — | 0 | 0 | $0 |
| John A Stalfort III | Direktor | 16. August 2023 G | 1.049.381 | 0 | 0 | $0 |
| Phillip B. Donenberg | Direktor | 16. August 2023 P | 114.111 | 0 | 0 | $0 |
| Kathleen Reape | Direktor | 22. Juni 2023 A | — | 0 | 0 | $0 |
| Laura Sepp-Lorenzino | Direktor | 22. Juni 2023 A | — | 0 | 0 | $0 |
| Paul B Manning | 10%-Eigentümer | 17. November 2023 P | 16.566.667 | 0 | 0 | $0 |
| R.A. Session II | 10%-Eigentümer | 13. Juli 2023 S | 8.871.747 | 0 | 0 | $0 |
Insider aus SEC-Einreichungen Form 3/4/5; Netto = nur P/S aus offenen Märkten
Aktivisten & 5%+-Eigentümer 4 Beteiligungen
Investoren mit SEC Schedule 13D — wirtschaftliches Eigentum über 5% mit der Absicht, Einfluss auf den Emittenten zu nehmen (aktivistische Beteiligungen, Board-Kampagnen, M&A). Jede Zeile zeigt den zuletzt bekannten Stand der Position dieses Melders.
| Anmelder | Eingereicht | Beteiligung | Status | Zweck | Einreichung |
|---|---|---|---|---|---|
| Paul B Manning, The Paul B. Manning Revocable Trust dated May 10, 2000, The PBM 2023 Grantor Retained Annuity Trust, The PBM 2025 Grantor Retained Annuity Trust, BKB Growth Investments, LLC, BKB G2 Investments, LLC | 3. Juni 2025 | 9,80% | Änderung | — | SEC |
| Paul B. Manning, The Paul B. Manning Revocable Trust dated May 10, 2000, The PBM 2023 Grantor Retained Annuity Trust, BKB Growth Investments, LLC, BKB G2 Investments, LLC ×3 Einreichungen | 21. August 2023 | — | Erste Einreichung | — | SEC |
| Astellas Pharma Inc., Astellas US Holding, Inc., Astellas Gene Therapies, Inc. (f/k/a Audentes Therapeutics, Inc.) ×2 Einreichungen | 18. August 2023 | — | Erste Einreichung | — | SEC |
| RA Session II, RA Session II, as Trustee of the Session 2020 Annuity Trust I, RA Session II, as Trustee of the Session 2020 Annuity Trust II | 5. Oktober 2020 | — | Erste Einreichung | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF-Besitz Gehalten von 44 ETFs
Gewichtung spiegelt nur direkte Aktienbestände (N-PORT) wider; gehebelte oder derivatbasierte Fonds können zusätzliche Swap-Exposure halten, die hier nicht angezeigt wird.
| Fonds | Gewicht | Anteile | Stand | Quelle |
|---|---|---|---|---|
| IBRN · iShares Trust | 1,53% | 18.665 SH | 8. August 2026 | Täglich |
| SBIO · ALPS ETF Trust | 1,02% | 282.348 NS | 31. Mai 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,82% | 47.669 NS | 30. April 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,40% | 322.791 NS | 30. April 2026 | N-PORT |
| FYC · First Trust Exchange-Traded AlphaDE… | 0,32% | 522.481 NS | 30. April 2026 | N-PORT |
| ESSC · Strategy Shares | 0,18% | 7.298 NS | 30. April 2026 | N-PORT |
| IBB · iShares Trust | 0,13% | 1.949.477 SH | 8. August 2026 | Täglich |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,13% | 15.639 SH | 8. August 2026 | Täglich |
| VFMO · VANGUARD WELLINGTON FUND | 0,11% | 332.492 SH | 8. August 2026 | Täglich |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,10% | 257.044 SH | 8. August 2026 | Täglich |
| IWO · iShares Trust | 0,09% | 2.159.516 SH | 8. August 2026 | Täglich |
| FYX · First Trust Exchange-Traded AlphaDE… | 0,08% | 154.894 NS | 30. April 2026 | N-PORT |
| BIB · ProShares Trust | 0,08% | 10.128 NS | 31. Mai 2026 | N-PORT |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,06% | 48.717 NS | 30. April 2026 | N-PORT |
| GINN · Goldman Sachs ETF Trust | 0,06% | 23.348 NS | 31. Mai 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,05% | 1.379.816 SH | 8. August 2026 | Täglich |
| IWM · iShares Trust | 0,05% | 6.118.574 SH | 8. August 2026 | Täglich |
| RSSL · Global X Funds | 0,04% | 95.596 NS | 30. April 2026 | N-PORT |
| ISCG · iShares Trust | 0,04% | 66.429 SH | 8. August 2026 | Täglich |
| GSSC · Goldman Sachs ETF Trust | 0,04% | 64.980 NS | 31. Mai 2026 | N-PORT |
| ITWO · ProShares Trust | 0,03% | 10.394 NS | 31. Mai 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,03% | 1.069.955 NS | 31. Mai 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,03% | 117.196 SH | 8. August 2026 | Täglich |
| TEXN · iShares Trust | 0,02% | 631 SH | 8. August 2026 | Täglich |
| ISCB · iShares Trust | 0,02% | 9.303 SH | 8. August 2026 | Täglich |
| VXF · VANGUARD INDEX FUNDS | 0,02% | 3.043.718 SH | 8. August 2026 | Täglich |
| VHT · VANGUARD WORLD FUND | 0,02% | 552.457 SH | 8. August 2026 | Täglich |
| UWM · ProShares Trust | 0,02% | 8.129 NS | 31. Mai 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 62.485 NS | 30. April 2026 | N-PORT |
| URTY · ProShares Trust | 0,01% | 8.221 NS | 31. Mai 2026 | N-PORT |
| WSML · iShares Trust | 0,01% | 8.217 SH | 8. August 2026 | Täglich |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 8.504 NS | 31. Mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,01% | 206 NS | 31. Mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 92.844 NS | 31. Mai 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,00% | 78.390 NS | 30. April 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 332.315 SH | 8. August 2026 | Täglich |
| IWV · iShares Trust | 0,00% | 69.995 SH | 8. August 2026 | Täglich |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 131.780 NS | 31. Mai 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 4.760 NS | 30. April 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 3.045 NS | 30. April 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 5.870 NS | 30. April 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 10.179 NS | 30. April 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 9.141.487 SH | 8. August 2026 | Täglich |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 20.636 SH | 8. August 2026 | Täglich |