CSTL Castle Biosciences, Inc. - Common stock

NASDAQ · Health Care · View on SEC EDGAR ↗
$30.23
Price · Aug 19, 2026
Fundamentals as of Jul 30, 2026

CSTL Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$30.23
Market Cap
$916M
P/E (TTM)
-37.2
EPS (TTM)
$-0.83
Revenue (TTM)
$344M
Div Yield
ROE
-5.2%
Debt/Equity
0.0
52W Range
$18 – $44

CSTL Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $344M
8-point trend, +1410.7%
2018-12-31 2025-12-31
EPS $-0.83
8-point trend, +84.4%
2018-12-31 2025-12-31
Free Cash Flow $28M
7-point trend, +366.0%
2019-12-31 2025-12-31
Margins -7.0%
2-point trend, -1.6%
2019-12-31 2020-12-31

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
CSTL
Peer Median
P/E (TTM)
5-point trend, -35.6%
-37.2
43.5
P/S (TTM)
5-point trend, -71.0%
2.7
1.4
P/B
5-point trend, -7.2%
1.9
1.5
EV / EBITDA
4-point trend, -703.8%
-307.1
Price / FCF
5-point trend, +184.2%
32.3

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
CSTL
Peer Median
Operating Margin
5-point trend, +70.8%
-12.4%
Net Profit Margin
5-point trend, +78.9%
-7.0%
-0.95%
ROA
5-point trend, +37.3%
-4.3%
-0.27%
ROE
5-point trend, +31.3%
-5.2%
-0.87%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
CSTL
Peer Median
Debt / Equity
4-point trend, -92.8%
0.0
Current Ratio
5-point trend, -63.0%
5.3
3.4
Quick Ratio
5-point trend, -64.2%
5.0

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
CSTL
Peer Median
Revenue YoY
5-point trend, +265.9%
3.7%
Revenue CAGR 3Y
5-point trend, +265.9%
35.9%
Revenue CAGR 5Y
5-point trend, +265.9%
40.6%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
CSTL
Peer Median
EPS (Diluted)
5-point trend, +33.1%
$-0.83

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
CSTL
Peer Median

CSTL Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 15 analysts
  • Strong Buy 7 46.7%
  • Buy 7 46.7%
  • Hold 1 6.7%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

9 analysts · 2026-08-17
Median target $44.00 +45.6%
Mean target $44.00 +45.6%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.27%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.07 $-0.41 0.34%
March 31, 2026 $-0.49 $-0.50 0.01%
Dec. 31, 2025 $-0.08 $-0.29 0.21%
Sept. 30, 2025 $-0.02 $-0.53 0.51%
June 30, 2025 $0.15 $-0.53 0.68%
March 31, 2025 $-0.20 $-0.07 -0.13%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CSTL $1.15B -46.9 3.7% -7.0% -5.2%
OMDA $922M -45.1 53.2% -4.9% -5.8% 65.7%
PNTG $975M 33.5 36.3% 3.1% 8.4%
AMN $606M -6.4 -8.5% -3.5% -15.3% 28.3%
LMRI
OPK -4.2 -14.9% -37.2% -17.6% 33.9%
GMRS
FLGT $816M -84.7 13.8% -18.8% -5.4% 40.6%
CVS $100.87B 57.1 7.8% 0.44% 2.4%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 17
Annual Income Statement data for CSTL
Metric Trend 20252024202320222021202020192018
Revenue 8-point trend, +1410.7% $344M $332M $220M $137M $94M $63M $52M $23M
Cost of Revenue 8-point trend, +1240.9% $71M $60M $45M $32M $16M $10M $7M $5M
Gross Profit 3-point trend, +202.8% · · · · · $53M $45M $17M
R&D Expense 8-point trend, +968.2% $52M $52M $54M $45M $30M $13M $7M $5M
SG&A Expense 8-point trend, +1292.3% $229M $200M $180M $143M $87M $48M $30M $16M
Operating Expenses 2-point trend, +74.6% · · · · · · $37M $21M
Operating Income 8-point trend, -1016.0% $-43M $9M $-68M $-73M $-40M $-7M $7M $-4M
Interest Expense 6-point trend, -99.5% · · $11.0K $17.0K $1.0K $3M $5M $2M
Interest Income 8-point trend, +48950.0% $12M $13M $11M $4M $68.0K $373.0K $312.0K $24.0K
Other Non-op 6-point trend, +152.9% $144.0K $0 $0 · · $0 $-3M $-272.0K
Income Tax 8-point trend, -59611.1% $-5M $3M $101.0K $-2M $-9M $84.0K $72.0K $9.0K
Net Income 8-point trend, -279.4% $-24M $18M $-57M $-67M $-31M $-10M $5M $-6M
EPS (Basic) 8-point trend, +84.4% $-0.83 $0.66 $-2.14 $-2.58 $-1.24 $-0.54 $0.35 $-5.33
EPS (Diluted) 8-point trend, +84.4% $-0.83 $0.62 $-2.14 $-2.58 $-1.24 $-0.54 $-0.21 $-5.33
Shares (Basic) 8-point trend, +1420.8% 28,986,000 27,776,000 26,802,000 26,054,000 25,137,000 18,929,000 8,584,000 1,906,000
Shares (Diluted) 8-point trend, +1420.8% 28,986,000 29,255,000 26,802,000 26,054,000 25,137,000 18,929,000 8,658,000 1,906,000
EBITDA 7-point trend, -127.8% $-2M $25M $-56M $-62M $-37M $-7M $7M ·
Balance Sheet 28
Annual Balance Sheet data for CSTL
Metric Trend 20252024202320222021202020192018
Cash & Equivalents 8-point trend, +2506.1% $117M $120M $99M $123M $330M $410M $99M $4M
Short-term Investments 3-point trend, +26.7% $183M $173M $144M · · · · ·
Receivables 8-point trend, +258.8% $43M $51M $38M $23M $17M $13M $15M $12M
Inventory 8-point trend, +1062.6% $10M $8M $8M $4M $2M $2M $1M $882.0K
Prepaid Expense 8-point trend, +1078.7% $8M $8M $6M $6M $5M $5M $2M $675.0K
Current Assets 8-point trend, +1892.1% $361M $360M $296M $292M $354M $430M $117M $18M
PP&E (Net) 5-point trend, +836.2% · · · $14M $10M $7M $2M $2M
PP&E (Gross) 3-point trend, +259.1% · · · · · $9M $3M $2M
Accum. Depreciation 3-point trend, +82.0% · · · · · $2M $1M $909.0K
Goodwill 5-point trend, +10700000.00 $11M $11M $11M $11M $0 · · ·
Intangibles 8-point trend, +2221950.0% $89M $96M $107M $116M $89M $0 $0 $4.0K
Other Non-current Assets 8-point trend, +1661.2% $4M $1M $1M $1M $2M $2M $135.0K $214.0K
Total Assets 8-point trend, +2482.3% $579M $531M $453M $447M $463M $439M $120M $22M
Accounts Payable 8-point trend, +1189.5% $19M $7M $10M $5M $3M $2M $2M $1M
Short-term Debt · · · · · · · $0
Current Liabilities 8-point trend, +919.4% $69M $49M $48M $36M $25M $21M $15M $7M
Capital Leases 6-point trend, +25217000.00 $25M $14M $14M $12M $7M $0 · ·
Deferred Tax 6-point trend, +2335000.00 $2M $2M $206.0K $428.0K $635.0K $0 · ·
Other Non-current Liabilities 4-point trend, -97.6% · · $25.0K $90.0K $124.0K $1M · ·
Total Liabilities 8-point trend, +231.6% $108M $75M $62M $48M $51M $24M $35M $32M
Long-term Debt 6-point trend, -59.0% $10M $10M $0 · · $0 $27M $24M
Total Debt 4-point trend, -60.0% $10M $10M · · · $0 $25M ·
Paid-in Capital 8-point trend, +75346.3% $695M $656M $609M $560M $505M $478M $137M $921.0K
Retained Earnings 8-point trend, -290.1% $-224M $-200M $-218M $-161M $-94M $-62M $-52M $-57M
AOCI 5-point trend, +267000.00 $267.0K $230.0K $136.0K $-381.0K $0 · · ·
Stockholders' Equity 8-point trend, +932.4% $471M $456M $391M $399M $412M $416M $85M $-57M
Liabilities + Equity 8-point trend, +2482.3% $579M $531M $453M $447M $463M $439M $120M $22M
Shares Outstanding 8-point trend, +1449.2% 29,686,314 28,483,195 27,410,532 26,553,681 25,378,520 24,812,487 17,130,907 1,916,224
Cash Flow 14
Annual Cash Flow data for CSTL
Metric Trend 20252024202320222021202020192018
D&A 6-point trend, +8537.9% $41M $16M $12M $11M $3M $472.0K · ·
Stock-based Comp 8-point trend, +15509.9% $46M $50M $51M $36M $22M $8M $1M $294.0K
Deferred Tax 8-point trend, -6228000.00 $-6M $1M $-223.0K $-2M $-9M $0 $0 $0
Amort. of Intangibles 8-point trend, +96672.2% $35M $11M $9M $8M $2M $0 $4.0K $36.0K
Other Non-cash 5-point trend, +296.7% $8M $-21M $-11M $-20M $-4M · · ·
Operating Cash Flow 8-point trend, +623.4% $64M $65M $-6M $-42M $-19M $10M $7M $-12M
CapEx 8-point trend, +12904.0% $36M $28M $14M $6M $3M $5M $937.0K $277.0K
Investing Cash Flow 8-point trend, -21693.1% $-60M $-50M $-16M $-167M $-67M $-5M $-937.0K $-277.0K
Stock Issued 3-point trend, -100.0% · · · · $0 $330M $66M ·
Net Stock Activity 2-point trend, -100.0% · · · · $0 $330M · ·
Financing Cash Flow 8-point trend, -143.9% $-7M $6M $-2M $2M $5M $306M $88M $16M
Net Change in Cash 8-point trend, -191.2% $-3M $21M $-24M $-207M $-80M $311M $94M $3M
Taxes Paid 8-point trend, +900.6% $2M $3M $198.0K $120.0K $16.0K $102.0K $-150.0K $160.0K
Free Cash Flow 7-point trend, +366.0% $28M $37M $-19M $-47M $-22M $5M $6M ·
Profitability 6
Annual Profitability data for CSTL
Metric Trend 20252024202320222021202020192018
Gross Margin 2-point trend, -1.6% · · · · · 84.5% 85.9% ·
Operating Margin 7-point trend, -188.0% -12.4% 2.6% -30.9% -53.2% -42.6% -10.4% 14.1% ·
Net Margin 7-point trend, -169.0% -7.0% 5.5% -26.2% -49.0% -33.3% -16.4% 10.2% ·
EBITDA Margin 7-point trend, -104.2% -0.59% 7.4% -25.3% -45.5% -39.0% -10.4% 14.1% ·
ROA 7-point trend, -158.6% -4.3% 3.7% -12.8% -14.8% -6.9% -3.7% 7.4% ·
ROE 7-point trend, -182.9% -5.2% 4.1% -14.8% -16.6% -7.6% -3.5% 6.3% ·
Liquidity & Solvency 5
Annual Liquidity & Solvency data for CSTL
Metric Trend 20252024202320222021202020192018
Current Ratio 7-point trend, -31.1% 5.3 7.3 6.2 8.1 14.2 20.6 7.6 ·
Quick Ratio 7-point trend, -32.7% 5.0 7.0 2.9 4.1 13.9 20.2 7.4 ·
Debt / Equity 4-point trend, -92.8% 0.0 0.0 · · · 0.0 0.3 ·
LT Debt / Equity 4-point trend, -91.0% 0.0 0.0 · · · 0.0 0.2 ·
Interest Coverage 5-point trend, -385562.0% · · -6179.7 -4285.6 -40079.0 -2.5 1.6 ·
Efficiency 3
Annual Efficiency data for CSTL
Metric Trend 20252024202320222021202020192018
Asset Turnover 7-point trend, -15.0% 0.6 0.7 0.5 0.3 0.2 0.2 0.7 ·
Inventory Turnover 7-point trend, +12.0% 7.7 7.5 7.5 10.7 7.5 5.6 6.9 ·
Receivables Turnover 7-point trend, +87.6% 7.3 7.4 7.1 6.7 6.3 4.6 3.9 ·
Per Share 7
Annual Per Share data for CSTL
Metric Trend 20252024202320222021202020192018
Book Value / Share 7-point trend, +219.2% $15.86 $16.00 $14.27 $15.03 $16.22 $16.75 $4.97 ·
Revenue / Share 7-point trend, +98.2% $11.88 $11.35 $8.20 $5.26 $3.74 $3.31 $5.99 ·
Cash Flow / Share 7-point trend, +174.0% $2.22 $2.22 $-0.21 $-1.60 $-0.76 $0.52 $0.81 ·
Cash / Share 7-point trend, -31.9% $3.93 $4.20 $3.61 $4.63 $12.99 $16.52 $5.77 ·
Dividend / Share Flat — no change across 8 periods $0 $0 $0 $0 $0 $0 $0 $0
Dividend Paid / Share Flat — no change across 8 periods $0 $0 $0 $0 $0 $0 $0 $0
EPS (TTM) 7-point trend, -295.2% $-0.83 $0.62 $-2.14 $-2.58 $-1.24 $-0.54 $-0.21 ·
Growth Rates 3
Annual Growth Rates data for CSTL
Metric Trend 20252024202320222021202020192018
Revenue YoY 5-point trend, -92.7% 3.7% 51.1% 60.4% 45.6% 50.2% · · ·
Revenue CAGR 3Y 3-point trend, -30.8% 35.9% 52.2% 51.9% · · · · ·
Revenue CAGR 5Y 40.6% · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for CSTL
Metric Trend 20252024202320222021202020192018
Revenue TTM 7-point trend, +563.7% $344M $332M $220M $137M $94M $63M $52M ·
Net Income TTM 7-point trend, -557.8% $-24M $18M $-57M $-67M $-31M $-10M $5M ·
Market Cap 7-point trend, +96.1% $1.15B $759M $592M $625M $1.09B $1.67B $589M ·
Enterprise Value 4-point trend, +68.0% $865M $476M · · · $1.26B $515M ·
P/E 7-point trend, +71.4% -46.9 43.0 -10.1 -9.1 -34.6 -124.4 -163.7 ·
P/S 7-point trend, -70.4% 3.4 2.3 2.7 4.6 11.6 26.6 11.4 ·
P/B 7-point trend, -64.5% 2.5 1.7 1.5 1.6 2.6 4.0 6.9 ·
P / Tangible Book 6-point trend, -22.4% 3.1 2.2 2.2 2.3 3.4 4.0 · ·
P / Cash Flow 7-point trend, -78.6% 17.9 11.7 -105.1 -15.0 -57.3 168.9 83.9 ·
P / FCF 7-point trend, -57.9% 40.8 20.8 -30.7 -13.2 -48.4 325.8 96.9 ·
EV / EBITDA 4-point trend, -703.8% -424.4 19.3 · · · -192.0 70.3 ·
EV / FCF 4-point trend, -64.0% 30.5 13.0 · · · 245.7 84.7 ·
EV / Revenue 4-point trend, -74.7% 2.5 1.4 · · · 20.1 9.9 ·
Earnings Yield 7-point trend, -249.2% -2.1% 2.3% -9.9% -11.0% -2.9% -0.80% -0.61% ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $344M$332M$220M$137M$94M
Operating Margin % -12.4%2.6%-30.9%-53.2%-42.6%
Net Income $-24M$18M$-57M$-67M$-31M
Diluted EPS $-0.83$0.62$-2.14$-2.58$-1.24
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.00.0
Current Ratio 5.37.36.28.114.2
Quick Ratio 5.07.02.94.113.9
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $28M$37M$-19M$-47M$-22M

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Institutional owners (13F) 191 filers · $512.7M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
28 (-7 vs prior Q) 30 (-3 vs prior Q) 68 (+1 vs prior Q) 58 (-2 vs prior Q) -2.9M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
VANGUARD GROUP INC $76,995,276 1,979,313 15.02% Shares
RTW INVESTMENTS, LP $66,263,290 2,778,335 12.92% Shares
VANGUARD CAPITAL MANAGEMENT LLC $29,251,953 1,226,497 5.70% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $20,052,722 840,785 3.91% Shares
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC $19,673,197 824,872 3.84% Shares
STATE STREET CORP $19,630,772 822,079 3.83% Shares
MACKENZIE FINANCIAL CORP $18,925,142 793,507 3.69% Shares
DIMENSIONAL FUND ADVISORS LP $17,759,831 744,647 3.46% Shares
GEODE CAPITAL MANAGEMENT, LLC $16,233,623 680,492 3.17% Shares
Jefferies Financial Group Inc. $15,440,275 647,391 3.01% Shares
Qube Research & Technologies Ltd $14,054,805 589,300 2.74% Shares
WASATCH ADVISORS LP $11,171,134 455,036 2.18% Shares
RENAISSANCE TECHNOLOGIES LLC $8,853,120 371,200 1.73% Shares
Point72 Asset Management, L.P. $8,522,010 357,317 1.66% Shares
KENNEDY CAPITAL MANAGEMENT LLC $8,308,648 348,371 1.62% Shares
Connor, Clark & Lunn Investment Management Ltd. $7,900,766 331,269 1.54% Shares
Portolan Capital Management, LLC $7,842,309 328,818 1.53% Shares
PANAGORA ASSET MANAGEMENT INC $7,179,804 301,040 1.40% Shares
Allspring Global Investments Holdings, LLC $6,975,410 292,470 1.36% Shares
KORNITZER CAPITAL MANAGEMENT INC /KS $6,302,005 264,235 1.23% Shares
SILVERCREST ASSET MANAGEMENT GROUP LLC $6,107,866 256,095 1.19% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $6,070,660 254,535 1.18% Shares
Advisors Capital Management, LLC $5,681,165 238,204 1.11% Shares
NEW YORK STATE COMMON RETIREMENT FUND $5,598,692 234,746 1.09% Shares
PALISADE CAPITAL MANAGEMENT, LP $5,531,554 231,931 1.08% Shares
BRIDGEWAY CAPITAL MANAGEMENT, LLC $5,278,911 221,338 1.03% Shares
Trexquant Investment LP $4,915,747 206,111 0.96% Shares
MILLENNIUM MANAGEMENT LLC $4,898,051 205,369 0.96% Shares
VANGUARD FIDUCIARY TRUST CO $4,710,232 197,494 0.92% Shares
FIRST TRUST ADVISORS LP $3,459,776 145,064 0.67% Shares
Parkman Healthcare Partners LLC $3,453,265 144,791 0.67% Shares
Empowered Funds, LLC $3,394,761 142,338 0.66% Shares
AIGH Capital Management LLC $3,166,207 132,755 0.62% Shares
Nuveen Asset Management, LLC $2,979,976 111,819 0.58% Shares
D. E. Shaw & Co., Inc. $2,690,018 112,789 0.52% Shares
Man Group plc $2,593,950 108,761 0.51% Shares
GOLDMAN SACHS GROUP INC $2,516,008 105,493 0.49% Shares
BlackRock, Inc. $2,509,807 105,233 0.49% Shares
TWO SIGMA INVESTMENTS, LP $2,393,920 100,374 0.47% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $2,211,754 92,736 0.43% Shares
SummitTX Capital, L.P. $1,884,579 79,018 0.37% Shares
ALGERT GLOBAL LLC $1,680,900 70,478 0.33% Shares
Orion Porfolio Solutions, LLC $1,661,248 69,654 0.32% Shares
BNP PARIBAS FINANCIAL MARKETS $1,659,268 69,571 0.32% Shares
Orion Portfolio Solutions, LLC $1,569,748 78,409 0.31% Shares
AMERICAN CENTURY COMPANIES INC $1,560,100 65,413 0.30% Shares
NORGES BANK $1,433,385 60,100 0.28% Shares
FMR LLC $1,324,080 55,517 0.26% Shares
ENVESTNET ASSET MANAGEMENT INC $1,315,494 55,157 0.26% Shares
Swiss National Bank $1,280,745 53,700 0.25% Shares
BANK OF AMERICA CORP /DE/ $1,265,100 53,044 0.25% Shares
TWO SIGMA ADVISERS, LP $1,163,071 29,899 0.23% Shares
Cubist Systematic Strategies, LLC $1,145,425 50,304 0.22% Shares
XTX Topco Ltd $952,164 39,923 0.19% Shares
JANE STREET GROUP, LLC $946,726 39,695 0.18% Shares
Bank of New York Mellon Corp $942,027 39,498 0.18% Shares
RHUMBLINE ADVISERS $930,379 39,010 0.18% Shares
Nebula Research & Development LLC $908,118 44,472 0.18% Shares
Y-Intercept (Hong Kong) Ltd $761,197 31,916 0.15% Shares
STRS OHIO $727,425 30,500 0.14% Shares
DEUTSCHE BANK AG\ $718,815 30,139 0.14% Shares
Engineers Gate Manager LP $703,098 29,480 0.14% Shares
BARCLAYS PLC $693,344 29,071 0.14% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $675,444 27,513 0.13% Shares
AlphaQuest LLC $665,812 17,116 0.13% Shares
ALLIANCEBERNSTEIN L.P. $665,305 27,100 0.13% Shares
Universal- Beteiligungs- und Servicegesellschaft mbH $601,521 25,221 0.12% Shares
CITADEL ADVISORS LLC $594,080 24,909 0.12% Shares
TRUIST FINANCIAL CORP $567,296 23,786 0.11% Shares
Inspire Investing, LLC $516,655 21,045 0.10% Shares
Schonfeld Strategic Advisors LLC $475,330 19,930 0.09% Shares
First Bank & Trust $443,395 18,591 0.09% Shares
VANGUARD ASSET MANAGEMENT, Ltd $421,024 17,653 0.08% Shares
MetLife Investment Management, LLC $405,641 17,008 0.08% Shares
JPMORGAN CHASE & CO $402,764 16,561 0.08% Shares
Counterpoint Mutual Funds LLC $393,764 16,510 0.08% Shares
Campbell & CO Investment Adviser LLC $392,953 16,476 0.08% Shares
Quantinno Capital Management LP $391,808 16,428 0.08% Shares
DIVERSIFY WEALTH MANAGEMENT, LLC $389,378 15,932 0.08% Shares
Diversify Advisory Services, LLC $389,378 15,932 0.08% Shares
PERKINS CAPITAL MANAGEMENT INC $384,939 16,140 0.08% Shares
Zurcher Kantonalbank (Zurich Cantonalbank) $371,559 15,579 0.07% Shares
JANUS HENDERSON GROUP PLC $369,083 15,037 0.07% Shares
TUDOR INVESTMENT CORP ET AL $344,919 14,462 0.07% Shares
CITIGROUP INC $343,822 14,416 0.07% Shares
LPL Financial LLC $339,147 14,220 0.07% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $328,772 13,785 0.06% Shares
Creative Planning $326,292 13,681 0.06% Shares
Oak Harvest Investment Services $321,617 13,485 0.06% Shares
Birchview Capital, LP $309,668 12,984 0.06% Shares
Parallel Advisors, LLC $308,404 12,931 0.06% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $299,151 12,543 0.06% Shares
Vanguard Global Advisers, LLC $274,323 11,502 0.05% Shares
Invesco Ltd. $274,156 11,495 0.05% Shares
TritonPoint Partners, LLC $257,485 10,796 0.05% Shares
Numerai GP LLC $246,800 10,348 0.05% Shares
Quadrature Capital Ltd $242,674 10,175 0.05% Shares
Lido Advisors, LLC $239,311 10,034 0.05% Shares
Green Alpha Advisors, LLC $237,093 9,941 0.05% Shares
Police & Firemen's Retirement System of New Jersey $235,042 9,855 0.05% Shares

Company insiders 16 insiders · 3 officers · 12 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Frank Stokes Chief Financial Officer Aug. 14, 2026 S 35,177 0 1 $-741,511
Bernhard E. Spiess Chief Operating Officer July 29, 2019 C 124,337 0 0 $0
Derek J Maetzold Pres. & Chief Exec. Officer Aug. 14, 2026 M 11,534 0 65 $-3,192,458
Rodney Cotton Director May 28, 2026 A 0 0 $0
Kim Caple Director May 28, 2026 A 0 0 $0
Ellen Goldberg Director May 28, 2026 A 0 0 $0
Miles Harrison Director May 28, 2026 A 0 0 $0
Tiffany Olson Director May 28, 2026 A 0 0 $0
Bradley G Cole Director May 28, 2026 A 0 0 $0
Daniel Bradbury Director May 28, 2026 A 908,578 0 0 $0
Joseph C. Cook III Director July 29, 2019 C 208,053 0 0 $0
Mara G. Aspinall Director July 29, 2019 C 40,848 0 0 $0
Bonnie H Anderson Director July 29, 2019 C 14,093 0 0 $0
KABAKOFF DAVID S Director July 29, 2019 X 1,833,577 0 0 $0
Kristen M Oelschlager Aug. 3, 2026 S 13,288 0 6 $-643,109
Tobin W Juvenal Nov. 24, 2025 S 77,694 0 5 $-606,103

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 1 position

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Sofinnova HealthQuest Partners, L.P. (“HealthQuest”), HealthQuest Venture Management, L.L.C. (“HealthQuest Management”), Dr. Garheng Kong (“Kong”) ×5 filings Oct. 9, 2020 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 56 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
HAPS · Harbor ETF Trust 0.40% 25,771 NS April 30, 2026 N-PORT
FYC · First Trust Exchange-Traded AlphaDE… 0.22% 95,132 NS April 30, 2026 N-PORT
ROSC · Lattice Strategies Trust 0.20% 4,486 NS April 30, 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0.06% 30,376 NS May 31, 2026 N-PORT
JPSE · J.P. Morgan Exchange-Traded Fund Tr… 0.06% 14,805 NS April 30, 2026 N-PORT
NUSC · Nushares ETF Trust 0.06% 30,863 NS April 30, 2026 N-PORT
FYX · First Trust Exchange-Traded AlphaDE… 0.06% 28,203 NS April 30, 2026 N-PORT
GINN · Goldman Sachs ETF Trust 0.05% 5,196 NS May 31, 2026 N-PORT
PSC · Principal Exchange-Traded Funds 0.05% 49,822 NS June 30, 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0.05% 8,869 NS April 30, 2026 N-PORT
AVSC · AMERICAN CENTURY ETF TRUST 0.04% 58,359 NS May 31, 2026 N-PORT
BIB · ProShares Trust 0.03% 1,100 NS May 31, 2026 N-PORT
RSSL · Global X Funds 0.02% 12,517 NS April 30, 2026 N-PORT
DFAS · Dimensional ETF Trust 0.02% 100,185 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.02% 1,352 NS May 31, 2026 N-PORT
DFAT · Dimensional ETF Trust 0.01% 81,322 NS April 30, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.01% 138,504 NS May 31, 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0.01% 13,531 NS April 30, 2026 N-PORT
DFSV · Dimensional ETF Trust 0.01% 30,295 NS April 30, 2026 N-PORT
UWM · ProShares Trust 0.01% 1,058 NS May 31, 2026 N-PORT
DXUV · Dimensional ETF Trust 0.01% 1,345 NS April 30, 2026 N-PORT
URTY · ProShares Trust 0.01% 1,070 NS May 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 83,333 NS April 30, 2026 N-PORT
TILT · FlexShares Trust 0.00% 3,234 NS April 30, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 1,162 NS May 31, 2026 N-PORT
DFSU · Dimensional ETF Trust 0.00% 2,610 NS April 30, 2026 N-PORT
HDG · ProShares Trust 0.00% 27 NS May 31, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.00% 7,521 NS April 30, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 12,934 NS April 30, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 1,372 NS April 30, 2026 N-PORT
AVSU · AMERICAN CENTURY ETF TRUST 0.00% 190 NS May 31, 2026 N-PORT
DFUV · Dimensional ETF Trust 0.00% 5,356 NS April 30, 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0.00% 18,371 NS May 31, 2026 N-PORT
AVUS · AMERICAN CENTURY ETF TRUST 0.00% 4,009 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS July 15, 2026 Daily
VTI · VANGUARD INDEX FUNDS July 15, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
ITOT · iShares Trust Aug. 5, 2026 Daily
IWV · iShares Trust Aug. 18, 2026 Daily
IWN · iShares Trust Aug. 17, 2026 Daily
IWM · iShares Trust Aug. 18, 2026 Daily
IBB · iShares Trust Aug. 18, 2026 Daily
IWC · iShares Trust Aug. 18, 2026 Daily
IHF · iShares Trust Aug. 18, 2026 Daily
SVAL · iShares Trust Aug. 5, 2026 Daily
TEXN · iShares Trust Aug. 5, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust Aug. 4, 2026 Daily
OMFS · Invesco Exchange-Traded Self-Indexe… July 13, 2026 Daily