HOWL Werewolf Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$0.41
Price · May 20, 2026
Fundamentals as of May 7, 2026

HOWL Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$0.41
Market Cap
$31M
P/E (TTM)
-0.5
EPS (TTM)
$-1.33
Revenue (TTM)
Div Yield
ROE
-183.6%
Debt/Equity
1.1
52W Range
$0 – $2

HOWL Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income
EPS $-1.33
6-point trend, +95.3%
2020-12-31 2025-12-31
Free Cash Flow $-60M
5-point trend, -39.0%
2021-12-31 2025-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
HOWL
Peer Median
P/E (TTM)
5-point trend, +56.2%
-0.5
P/B
5-point trend, -41.7%
1.2
3.3
EV / EBITDA
3-point trend, +94.3%
-0.0
Price / FCF
5-point trend, +93.2%
-0.5

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
HOWL
Peer Median
ROA
5-point trend, -70.8%
-62.0%
-66.0%
ROE
5-point trend, -491.4%
-183.6%
-128.2%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
HOWL
Peer Median
Debt / Equity
3-point trend, +1800.3%
1.1
1.0
Current Ratio
5-point trend, -88.1%
1.6
2.6
Quick Ratio
5-point trend, -88.1%
1.6

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
HOWL
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
HOWL
Peer Median
EPS (Diluted)
5-point trend, +87.8%
$-1.33

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
HOWL
Peer Median

HOWL Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 10 analysts
  • Strong Buy 4 40.0%
  • Buy 4 40.0%
  • Hold 2 20.0%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

3 analysts · 2026-05-19
Median target $7.00 +1592.5%
Mean target $7.00 +1592.5%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.05%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.28 $-0.29 0.01%
Dec. 31, 2025 $-0.17 $-0.35 0.18%
Sept. 30, 2025 $-0.36 $-0.40 0.04%
June 30, 2025 $-0.40 $-0.49 0.09%
March 31, 2025 $-0.40 $-0.40 0.00%
Dec. 31, 2024 $-0.46 $-0.43 -0.03%

Peer Comparison Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
HOWL $31M -0.5 -183.6%
MRKR $25M -1.9 -46.2% -343.0% -89.1%
CRIS $13M -1.7 -13.4% -80.3% 177.9%
XCUR $35M -6.9 -77.3%
OSRH
QNCX $187M -2.0 700.5%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for HOWL
Metric Trend 202520242023202220212020
R&D Expense 6-point trend, +169.4% $45M $56M $42M $54M $35M $17M
SG&A Expense 6-point trend, +175.0% $16M $19M $19M $19M $15M $6M
Operating Expenses 6-point trend, +170.8% $61M $75M $60M $72M $50M $22M
Operating Income 6-point trend, -170.8% $-61M $-74M $-41M $-56M $-50M $-22M
Interest Expense 2-point trend, +3139000.00 · · $3M $0 · ·
Interest Income 4-point trend, +62.9% $3M $7M $7M $2M · ·
Other Non-op 6-point trend, -72.6% $2M $2M $-1M $338.0K $104.0K $7M
Income Tax $0 · · · · ·
Net Income 6-point trend, -304.4% $-61M $-71M $-37M $-54M $-50M $-15M
EPS (Basic) 6-point trend, +95.3% $-1.32 $-1.63 $-1.05 $-1.86 $-10.94 $-28.08
EPS (Diluted) 6-point trend, +95.3% $-1.33 $-1.63 $-1.05 $-1.86 $-10.94 $-28.08
Shares (Basic) 6-point trend, +4479.0% 46,018,888 43,332,088 35,646,572 28,863,935 18,455,000 1,005,000
Shares (Diluted) 6-point trend, +4557.7% 46,810,252 43,859,664 35,646,572 28,863,935 18,455,000 1,005,000
EBITDA 5-point trend, -21.1% $-61M $-74M $-41M $-56M $-50M ·
Balance Sheet 23
Annual Balance Sheet data for HOWL
Metric Trend 202520242023202220212020
Cash & Equivalents 6-point trend, -38.4% $57M $111M $134M $129M $158M $93M
Prepaid Expense 6-point trend, +346.5% $2M $2M $3M $4M $4M $344.0K
Current Assets 6-point trend, -36.9% $59M $113M $138M $140M $161M $93M
PP&E (Net) 6-point trend, +620.1% $5M $6M $8M $9M $3M $651.0K
PP&E (Gross) 6-point trend, +1268.8% $11M $11M $11M $10M $3M $826.0K
Accum. Depreciation · · · · $391.0K ·
Other Non-current Assets 6-point trend, +5000.00 $5.0K $320.0K $594.0K $1M $649.0K $0
Total Assets 6-point trend, -28.0% $69M $127M $175M $160M $179M $96M
Accounts Payable 6-point trend, -26.2% $754.0K $3M $1M $1M $2M $1M
Accrued Liabilities 6-point trend, +50.8% $5M $11M $9M $14M $9M $4M
Short-term Debt 4-point trend, +28236000.00 $28M $0 $7M $0 · ·
Current Liabilities 6-point trend, +584.1% $36M $15M $19M $24M $12M $5M
Capital Leases 6-point trend, +312.2% $8M $9M $11M $13M $15M $2M
Other Non-current Liabilities 4-point trend, -100.0% · · $0 $191.0K $0 $31.0K
Total Liabilities 6-point trend, +521.1% $45M $54M $63M $38M $26M $7M
Long-term Debt 3-point trend, -19.8% $32M $32M $40M · · ·
Total Debt 3-point trend, +323.5% $28M $0 $7M · · ·
Common Stock 6-point trend, +150.0% $5.0K $5.0K $4.0K $3.0K $2.0K $2.0K
Paid-in Capital 6-point trend, +500210000.00 $500M $488M $455M $429M $406M $0
Retained Earnings 6-point trend, -816.6% $-475M $-415M $-344M $-307M $-253M $-52M
Stockholders' Equity 6-point trend, +147.8% $25M $73M $111M $122M $153M $-52M
Liabilities + Equity 6-point trend, -28.0% $69M $127M $175M $160M $179M $96M
Shares Outstanding 6-point trend, +4004.5% 48,596,817 44,827,159 39,107,048 31,515,074 27,313,000 1,184,000
Cash Flow 10
Annual Cash Flow data for HOWL
Metric Trend 202520242023202220212020
Stock-based Comp 6-point trend, +888.1% $6M $9M $8M $7M $4M $632.0K
Deferred Tax Flat — no change across 6 periods $0 $0 $0 $0 $0 $0
Operating Cash Flow 6-point trend, -223.7% $-60M $-56M $-33M $-41M $-43M $-19M
CapEx 6-point trend, -100.0% $0 $254.0K $769.0K $4M $498.0K $560.0K
Investing Cash Flow 6-point trend, +100.0% $0 $-254.0K $-769.0K $-4M $-498.0K $-560.0K
Stock Issued 5-point trend, +5939000.00 $6M $24M $18M $16M $0 ·
Net Stock Activity 4-point trend, -63.3% $6M $24M $18M $16M · ·
Financing Cash Flow 6-point trend, -93.6% $6M $13M $58M $16M $109M $94M
Net Change in Cash 6-point trend, -172.7% $-54M $-43M $25M $-28M $66M $75M
Free Cash Flow 5-point trend, -39.0% $-60M $-56M $-33M $-44M $-43M ·
Profitability 2
Annual Profitability data for HOWL
Metric Trend 202520242023202220212020
ROA 5-point trend, -70.8% -62.0% -46.7% -22.3% -31.7% -36.3% ·
ROE 5-point trend, -491.4% -183.6% -86.6% -33.4% -42.5% -31.0% ·
Liquidity & Solvency 4
Annual Liquidity & Solvency data for HOWL
Metric Trend 202520242023202220212020
Current Ratio 5-point trend, -88.1% 1.6 7.4 7.1 5.8 13.6 ·
Quick Ratio 5-point trend, -88.1% 1.6 7.3 6.9 5.4 13.3 ·
Debt / Equity 3-point trend, +1800.3% 1.1 0.0 0.1 · · ·
Interest Coverage · · -12.9 · · ·
Per Share 4
Annual Per Share data for HOWL
Metric Trend 202520242023202220212020
Book Value / Share 5-point trend, -90.9% $0.51 $1.64 $2.85 $3.89 $5.59 ·
Cash Flow / Share 5-point trend, +44.6% $-1.29 $-1.28 $-0.91 $-1.41 $-2.32 ·
Cash / Share 5-point trend, -79.6% $1.17 $2.48 $3.44 $4.11 $5.77 ·
EPS (TTM) 5-point trend, +87.8% $-1.33 $-1.63 $-1.05 $-1.86 $-10.94 ·
Valuation (TTM) 11
Annual Valuation (TTM) data for HOWL
Metric Trend 202520242023202220212020
Net Income TTM 5-point trend, -21.7% $-61M $-71M $-37M $-54M $-50M ·
Market Cap 5-point trend, -90.5% $31M $66M $151M $64M $325M ·
Enterprise Value 3-point trend, -91.4% $2M $-45M $23M · · ·
P/E 5-point trend, +56.2% -0.5 -0.9 -3.7 -1.1 -1.1 ·
P/B 5-point trend, -41.7% 1.2 0.9 1.4 0.5 2.1 ·
P / Tangible Book 5-point trend, -41.7% 1.2 0.9 1.4 0.5 2.1 ·
P / Cash Flow 5-point trend, +93.3% -0.5 -1.2 -4.6 -1.6 -7.6 ·
P / FCF 5-point trend, +93.2% -0.5 -1.2 -4.5 -1.5 -7.5 ·
EV / EBITDA 3-point trend, +94.3% -0.0 0.6 -0.6 · · ·
EV / FCF 3-point trend, +95.3% -0.0 0.8 -0.7 · · ·
Earnings Yield 5-point trend, -128.4% -209.8% -110.1% -27.2% -90.7% -91.9% ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Net Income $-61M$-71M$-37M$-54M$-50M
Diluted EPS $-1.33$-1.63$-1.05$-1.86$-10.94
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 1.10.00.1
Current Ratio 1.67.47.15.813.6
Quick Ratio 1.67.36.95.413.3
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-60M$-56M$-33M$-44M$-43M

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