IRD — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Caligan Partners LP | $24,976,815 | 6,077,084 | 10.37% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $24,782,375 | 6,029,775 | 10.29% | Shares |
| BIOS Capital Management, LP | $15,138,893 | 3,683,429 | 6.29% | Shares |
| BlackRock, Inc. | $12,808,762 | 3,116,487 | 5.32% | Shares |
| Balyasny Asset Management L.P. | $12,691,129 | 3,087,866 | 5.27% | Shares |
| Nantahala Capital Management, LLC | $12,582,185 | 3,061,359 | 5.22% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $12,160,187 | 2,958,683 | 5.05% | Shares |
| Boxer Capital Management, LLC | $11,569,650 | 2,815,000 | 4.80% | Shares |
| Trails Edge Capital Partners, LP | $11,276,434 | 2,743,658 | 4.68% | Shares |
| MILLENNIUM MANAGEMENT LLC | $9,461,635 | 2,302,101 | 3.93% | Shares |
| GREAT POINT PARTNERS LLC | $8,097,469 | 1,970,187 | 3.36% | Shares |
| MARSHALL WACE, LLP | $7,996,453 | 1,945,609 | 3.32% | Shares |
| ADAR1 Capital Management, LLC | $7,331,340 | 1,783,781 | 3.04% | Shares |
| GOLDMAN SACHS GROUP INC | $6,276,912 | 1,527,229 | 2.61% | Shares |
| Woodline Partners LP | $5,896,670 | 1,434,713 | 2.45% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $5,622,928 | 1,367,712 | 2.33% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $4,888,907 | 1,189,515 | 2.03% | Shares |
| VANGUARD GROUP INC | $4,669,022 | 2,322,897 | 1.94% | Shares |
| Opaleye Management Inc. | $4,623,750 | 1,125,000 | 1.92% | Shares |
| SummitTX Capital, L.P. | $4,140,213 | 1,007,351 | 1.72% | Shares |
| STATE STREET CORP | $3,247,459 | 790,136 | 1.35% | Shares |
| Bleichroeder LP | $3,028,421 | 736,842 | 1.26% | Shares |
| UBS Group AG | $2,810,808 | 683,895 | 1.17% | Shares |
| CITADEL ADVISORS LLC | $2,735,871 | 665,662 | 1.14% | Shares |
| MORGAN STANLEY | $1,910,739 | 464,900 | 0.79% | Shares |
| NORTHERN TRUST CORP | $1,817,253 | 442,154 | 0.75% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $1,686,641 | 410,375 | 0.70% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1,528,715 | 371,950 | 0.63% | Shares |
| Squarepoint Ops LLC | $1,359,518 | 330,783 | 0.56% | Shares |
| TWO SIGMA INVESTMENTS, LP | $1,043,784 | 253,962 | 0.43% | Shares |
| AWM Investment Company, Inc. | $955,945 | 232,590 | 0.40% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $809,247 | 196,897 | 0.34% | Shares |
| JANE STREET GROUP, LLC | $776,741 | 188,988 | 0.32% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $678,368 | 165,053 | 0.28% | Shares |
| Mink Brook Asset Management LLC | $662,553 | 161,205 | 0.28% | Shares |
| XTX Topco Ltd | $592,230 | 144,095 | 0.25% | Shares |
| Seven Fleet Capital Management LP | $588,293 | 143,137 | 0.24% | Shares |
| Creative Planning | $527,584 | 128,366 | 0.22% | Shares |
| Texas Capital Bank Wealth Management Services Inc | $503,594 | 122,529 | 0.21% | Shares |
| Bank of New York Mellon Corp | $503,390 | 122,479 | 0.21% | Shares |
| Stonepine Capital Management, LLC | $413,951 | 100,718 | 0.17% | Shares |
| Jump Financial, LLC | $389,711 | 94,820 | 0.16% | Shares |
| Nuveen, LLC | $293,220 | 71,343 | 0.12% | Shares |
| Palogic Value Management, L.P. | $267,512 | 65,088 | 0.11% | Shares |
| Aureus Asset Management, LLC | $239,202 | 58,200 | 0.10% | Shares |
| Regency Capital Management Inc.\DE | $238,380 | 58,000 | 0.10% | Shares |
| BANK OF AMERICA CORP /DE/ | $226,070 | 55,005 | 0.09% | Shares |
| DEUTSCHE BANK AG\ | $219,113 | 53,312 | 0.09% | Shares |
| Invesco Ltd. | $218,779 | 53,231 | 0.09% | Shares |
| WELLS FARGO & COMPANY/MN | $216,321 | 52,633 | 0.09% | Shares |
| RHUMBLINE ADVISERS | $211,512 | 51,464 | 0.09% | Shares |
| EntryPoint Capital, LLC | $209,129 | 50,883 | 0.09% | Shares |
| Quadrature Capital Ltd | $190,659 | 46,389 | 0.08% | Shares |
| Empowered Funds, LLC | $172,887 | 42,065 | 0.07% | Shares |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $172,887 | 42,065 | 0.07% | Shares |
| MANGROVE PARTNERS IM, LLC | $171,457 | 41,717 | 0.07% | Shares |
| MetLife Investment Management, LLC | $132,375 | 32,208 | 0.05% | Shares |
| CAPTRUST FINANCIAL ADVISORS | $131,520 | 32,000 | 0.05% | Shares |
| CITIGROUP INC | $123,678 | 30,092 | 0.05% | Shares |
| ALLIANCEBERNSTEIN L.P. | $115,479 | 25,380 | 0.05% | Shares |
| Miller Financial Services LLC | $110,970 | 27,000 | 0.05% | Shares |
| SIMPLEX TRADING, LLC | $105,022 | 25,553 | 0.04% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $101,340 | 24,657 | 0.04% | Shares |
| JPMORGAN CHASE & CO | $90,128 | 22,199 | 0.04% | Shares |
| JANE STREET GROUP, LLC | $84,666 | 20,600 | 0.04% | Call option |
| Point72 Asset Management, L.P. | $77,769 | 18,922 | 0.03% | Shares |
| JAMES INVESTMENT RESEARCH, INC. | $67,256 | 16,364 | 0.03% | Shares |
| NewEdge Advisors, LLC | $67,256 | 16,364 | 0.03% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $65,550 | 15,949 | 0.03% | Shares |
| State of Wyoming | $65,365 | 15,904 | 0.03% | Shares |
| Police & Firemen's Retirement System of New Jersey | $64,909 | 15,793 | 0.03% | Shares |
| RAYMOND JAMES FINANCIAL INC | $61,683 | 15,008 | 0.03% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $59,595 | 14,500 | 0.02% | Shares |
| Vanguard Global Advisers, LLC | $58,946 | 14,342 | 0.02% | Shares |
| OSAIC HOLDINGS, INC. | $57,128 | 13,900 | 0.02% | Shares |
| BARCLAYS PLC | $54,897 | 13,357 | 0.02% | Shares |
| KESTRA PRIVATE WEALTH SERVICES, LLC | $52,608 | 12,800 | 0.02% | Shares |
| Stokes Family Office, LLC | $49,813 | 12,120 | 0.02% | Shares |
| Engineers Gate Manager LP | $49,579 | 12,063 | 0.02% | Shares |
| First City Capital Management, Inc. | $48,646 | 11,836 | 0.02% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $47,536 | 11,566 | 0.02% | Shares |
| VOYA INVESTMENT MANAGEMENT LLC | $45,280 | 11,017 | 0.02% | Shares |
| STRS OHIO | $43,155 | 10,500 | 0.02% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $33,624 | 8,181 | 0.01% | Shares |
| COMERICA BANK | $24,120 | 12,000 | 0.01% | Shares |
| Legal & General Group Plc | $21,384 | 5,203 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $19,975 | 4,860 | 0.01% | Shares |
| Hilton Head Capital Partners, LLC | $18,380 | 4,472 | 0.01% | Shares |
| Russell Investments Group, Ltd. | $17,599 | 4,282 | 0.01% | Shares |
| Farther Finance Advisors, LLC | $14,344 | 3,490 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $13,053 | 3,176 | 0.01% | Shares |
| TD Waterhouse Canada Inc. | $12,528 | 3,000 | 0.01% | Shares |
| NATIONAL BANK OF CANADA /FI/ | $8,278 | 2,014 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $8,000 | 2,095 | 0.00% | Shares |
| GGM Financial LLC | $4,131 | 1,005 | 0.00% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $3,029 | 737 | 0.00% | Shares |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | $2,178 | 521 | 0.00% | Shares |
| Quarry LP | $2,063 | 502 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $2,059 | 501 | 0.00% | Shares |
| Sterling Capital Management LLC | $773 | 188 | 0.00% | Shares |
| FMR LLC | $584 | 142 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $259 | 63 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $181 | 43,937 | 0.00% | Shares |
| STONERIDGE INVESTMENT PARTNERS LLC | $47 | 12,695 | 0.00% | Shares |
| Annandale Capital, LLC | $41 | 10,000 | 0.00% | Shares |