KURA Kura Oncology, Inc. - Common Stock
$12.73
Price · Aug 19, 2026
Fundamentals as of Aug 12, 2026
52W Range
$7–$13
97% of range
Analyst Rating
BUY
22 analysts
Price Target
$32
+151% upside
P/E (TTM)
-4.0
ROE
-116.2%
Net Profit Margin
-413.0%
KURA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$12.73
Market Cap
$1.12B
P/E (TTM)
-4.0
EPS (TTM)
$-3.18
Revenue (TTM)
$67M
Div Yield
—
ROE
-116.2%
Debt/Equity
0.1
52W Range
$7 – $13
KURA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$67M
2023-12-31
→
2025-12-31
EPS
$-3.18
2020-12-31
→
2025-12-31
Free Cash Flow
$-71M
2020-12-31
→
2025-12-31
Margins
-413.0%
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
KURA
Peer Median
P/E (TTM)
-4.0
—
P/S (TTM)
16.6
12.8
P/B
6.4
3.4
EV / EBITDA
-3.2
—
Price / FCF
-15.8
—
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
KURA
Peer Median
Operating Margin
-449.9%
—
Net Profit Margin
-413.0%
-294.4%
ROA
-37.2%
-31.3%
ROE
-116.2%
-38.1%
ROIC
-165.3%
—
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
KURA
Peer Median
Debt / Equity
0.1
—
Current Ratio
6.1
10.9
Quick Ratio
1.3
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
KURA
Peer Median
Revenue YoY
25.2%
—
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
KURA
Peer Median
KURA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
22 analysts
- Strong Buy 6 27.3%
- Buy 13 59.1%
- Hold 3 13.6%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
12 analysts · 2026-08-19
Median
$28.00
← Below all targets
$12.73
Low
$15.00
High
$76.00
Median target
$28.00
+120.0%
Mean target
$32.00
+151.4%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-0.17%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| June 30, 2026 | $-0.77 | $-0.90 | 0.13% |
| March 31, 2026 | $-0.83 | $-0.65 | -0.18% |
| Dec. 31, 2025 | $-0.92 | $-0.49 | -0.43% |
| Sept. 30, 2025 | $-0.85 | $-0.87 | 0.02% |
| June 30, 2025 | $-0.75 | $-0.47 | -0.28% |
| March 31, 2025 | $-0.66 | $-0.40 | -0.26% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| KURA | $913M | -3.3 | 25.2% | -413.0% | -116.2% | — |
| SANA | $1.09B | -4.2 | — | — | -172.3% | — |
| VOR | $506M | -0.2 | — | — | 83.4% | — |
| ODTX | — | — | — | — | — | — |
| SVRA | $1.23B | -11.4 | — | — | -73.4% | — |
| AVTX | $336M | -3.1 | -86.6% | -132642.4% | -83.4% | — |
| JANX | $833M | -7.5 | -5.5% | -1136.2% | -11.7% | — |
| ANNX | $750M | -3.7 | — | — | -100.7% | — |
| SLDB | $445M | -2.8 | — | — | -79.5% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 15
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue | $67M | $54M | $0 | |
| R&D Expense | $251M | $170M | $115M | |
| SG&A Expense | $120M | $77M | $51M | |
| Operating Expenses | $371M | $247M | $166M | |
| Operating Income | $-304M | $-193M | $-166M | |
| Interest Expense | · | · | $2M | |
| Other Non-op | $25M | $21M | $13M | |
| Pretax Income | $-278M | $-172M | $-153M | |
| Income Tax | $297.0K | $2M | $0 | |
| Net Income | $-279M | $-174M | $-153M | |
| EPS (Basic) | $-3.18 | $-2.02 | $-2.08 | |
| EPS (Diluted) | $-3.18 | $-2.02 | $-2.08 | |
| Shares (Basic) | 87,676,000 | 86,161,000 | 73,229,000 | |
| Shares (Diluted) | 87,676,000 | 86,161,000 | 73,229,000 | |
| EBITDA | $-304M | $-193M | · |
Balance Sheet 23
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $149M | $224M | $37M | |
| Receivables | $9M | $2M | · | |
| Inventory | $413.0K | $0 | · | |
| Prepaid Expense | $32M | $15M | $9M | |
| Current Assets | $709M | $745M | $432M | |
| PP&E (Net) | $8M | $2M | $2M | |
| PP&E (Gross) | $11M | $5M | $4M | |
| Accum. Depreciation | $3M | $3M | $2M | |
| Other Non-current Assets | $15M | $8M | $8M | |
| Total Assets | $738M | $760M | $449M | |
| Accounts Payable | $5M | $1M | $2M | |
| Current Liabilities | $117M | $79M | $35M | |
| Capital Leases | $9M | $5M | $6M | |
| Other Non-current Liabilities | $3M | $2M | $705.0K | |
| Total Liabilities | $564M | $347M | $52M | |
| Long-term Debt | $10M | $10M | · | |
| Total Debt | $10M | $10M | $9M | |
| Common Stock | $9.0K | $8.0K | $7.0K | |
| Retained Earnings | $-1.17B | $-895M | $-721M | |
| AOCI | $1M | $764.0K | $-1M | |
| Stockholders' Equity | $174M | $414M | $397M | |
| Liabilities + Equity | $738M | $760M | $449M | |
| Shares Outstanding | 87,855,000 | 78,229,000 | 74,350,000 |
Cash Flow 8
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Stock-based Comp | $37M | $34M | $28M | |
| Operating Cash Flow | $-64M | $134M | $-125M | |
| CapEx | $7M | $472.0K | $168.0K | |
| Investing Cash Flow | $-13M | $-102M | $16M | |
| Financing Cash Flow | $2M | $154M | $95M | |
| Net Change in Cash | $-75M | $187M | $-14M | |
| Taxes Paid | $2M | · | · | |
| Free Cash Flow | $-71M | $134M | $-125M |
Profitability 7
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Operating Margin | -449.9% | -358.6% | · | |
| Net Margin | -413.0% | -322.9% | · | |
| Pretax Margin | -412.5% | -319.1% | · | |
| EBITDA Margin | -449.9% | -358.6% | · | |
| ROA | -37.2% | -28.8% | -33.7% | |
| ROE | -116.2% | -41.5% | -36.9% | |
| ROIC | -165.3% | -46.2% | · |
Liquidity & Solvency 4
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 6.1 | 9.5 | 12.3 | |
| Quick Ratio | 1.3 | 2.9 | 1.1 | |
| Debt / Equity | 0.1 | 0.0 | 0.0 | |
| LT Debt / Equity | 0.1 | 0.0 | 0.0 |
Efficiency 2
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Asset Turnover | 0.1 | 0.1 | · | |
| Receivables Turnover | 12.4 | · | · |
Growth Rates 1
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue YoY | 25.2% | · | · |
Valuation (TTM) 14
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue TTM | $67M | $54M | $0 | |
| Net Income TTM | $-279M | $-174M | $-153M | |
| Market Cap | $913M | $681M | $1.07B | |
| Enterprise Value | $773M | $466M | $1.04B | |
| P/E | -3.3 | -4.3 | -6.9 | |
| P/S | 13.5 | 12.6 | · | |
| P/B | 5.2 | 1.6 | 2.7 | |
| P / Tangible Book | 5.2 | 1.6 | 2.7 | |
| P / Cash Flow | -14.2 | 5.1 | -8.6 | |
| P / FCF | -12.9 | 5.1 | -8.6 | |
| EV / EBITDA | -2.5 | -2.4 | · | |
| EV / FCF | -10.9 | 3.5 | -8.3 | |
| EV / Revenue | 11.5 | 8.7 | · | |
| Earnings Yield | -30.6% | -23.2% | -14.5% |
Income Statement 15
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Revenue | $21M | $18M | $17M | $21M | $15M | $14M | |
| Cost of Revenue | $243.0K | $262.0K | · | · | · | · | |
| R&D Expense | $62M | $65M | $64M | $68M | $63M | $56M | |
| SG&A Expense | $32M | $32M | $39M | $33M | $25M | $23M | |
| Operating Expenses | $94M | $97M | $104M | $101M | $88M | $79M | |
| Operating Income | $-73M | $-79M | $-86M | $-80M | $-73M | $-65M | |
| Other Non-op | $5M | $5M | $5M | $6M | $7M | $7M | |
| Pretax Income | $-68M | $-73M | $-81M | $-74M | $-66M | $-57M | |
| Income Tax | $5.0K | $8.0K | $71.0K | $0 | $0 | $226.0K | |
| Net Income | $-68M | $-73M | $-81M | $-74M | $-66M | $-57M | |
| EPS (Basic) | $-0.77 | $-0.83 | $-0.92 | $-0.85 | $-0.75 | $-0.66 | |
| EPS (Diluted) | $-0.77 | $-0.83 | $-0.92 | $-0.85 | $-0.75 | $-0.66 | |
| Shares (Basic) | 88,855,000 | 88,610,000 | -174,970,000 | 87,645,000 | 87,586,000 | 87,415,000 | |
| Shares (Diluted) | 88,855,000 | 88,610,000 | -174,970,000 | 87,645,000 | 87,586,000 | 87,415,000 | |
| EBITDA | $-73M | $-79M | · | $-80M | $-73M | $-65M |
Balance Sheet 23
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $70M | $39M | $149M | $95M | $82M | $51M | |
| Receivables | $9M | $9M | $9M | $36M | $5M | $49M | |
| Inventory | $2M | $843.0K | $413.0K | · | · | · | |
| Prepaid Expense | $28M | $33M | $32M | $35M | $25M | $17M | |
| Current Assets | $559M | $624M | $709M | $621M | $660M | $724M | |
| PP&E (Net) | $8M | $8M | $8M | $7M | $4M | $2M | |
| PP&E (Gross) | $11M | $11M | $11M | $11M | $8M | $6M | |
| Accum. Depreciation | $4M | $3M | $3M | $4M | $4M | $4M | |
| Other Non-current Assets | $14M | $14M | $15M | $14M | $11M | $9M | |
| Total Assets | $588M | $653M | $738M | $649M | $682M | $744M | |
| Accounts Payable | $2M | $7M | $5M | $5M | $2M | $5M | |
| Current Liabilities | $118M | $101M | $117M | $121M | $107M | $90M | |
| Capital Leases | $13M | $13M | $9M | $8M | $8M | $8M | |
| Other Non-current Liabilities | $4M | $3M | $3M | $3M | $3M | $2M | |
| Total Liabilities | $539M | $545M | $564M | $407M | $377M | $379M | |
| Long-term Debt | $10M | · | $10M | $10M | $10M | $10M | |
| Total Debt | $10M | $10M | · | $10M | $10M | $10M | |
| Common Stock | $9.0K | $9.0K | $9.0K | $9.0K | $9.0K | $8.0K | |
| Retained Earnings | $-1.32B | $-1.25B | $-1.17B | $-1.09B | $-1.02B | $-953M | |
| AOCI | · | · | $1M | · | $711.0K | $974.0K | |
| Stockholders' Equity | $48M | $108M | $174M | $243M | $305M | $364M | |
| Liabilities + Equity | $588M | $653M | $738M | $649M | $682M | $744M | |
| Shares Outstanding | 88,954,000 | 88,763,000 | 87,855,000 | 87,016,000 | 86,797,000 | 80,778,000 |
Cash Flow 7
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Stock-based Comp | $8M | $8M | $11M | $11M | $7M | $8M | |
| Operating Cash Flow | $-63M | $-86M | $117M | $-81M | $-29M | $-72M | |
| CapEx | $656.0K | $128.0K | $2M | $3M | $1M | $292.0K | |
| Investing Cash Flow | $92M | $-24M | $-65M | $94M | $59M | $-101M | |
| Financing Cash Flow | $1M | $69.0K | $1M | $0 | $515.0K | $143.0K | |
| Net Change in Cash | $31M | $-110M | $54M | $13M | $31M | $-173M | |
| Free Cash Flow | · | $-86M | · | · | · | $-72M |
Profitability 7
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Operating Margin | -349.8% | -431.5% | · | -385.5% | -475.3% | -458.6% | |
| Net Margin | -327.3% | -401.5% | · | -357.2% | -432.5% | -407.1% | |
| Pretax Margin | -327.3% | -401.4% | · | -357.2% | -432.5% | -405.5% | |
| EBITDA Margin | -349.8% | -431.5% | · | -385.5% | -475.3% | -458.6% | |
| ROA | -10.8% | -10.5% | · | -13.1% | -11.0% | -8.8% | |
| ROE | -38.6% | -31.1% | · | -22.2% | -17.1% | -13.2% | |
| ROIC | -125.4% | -67.0% | · | · | · | -17.4% |
Liquidity & Solvency 4
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 4.7 | 6.1 | · | 5.1 | 6.2 | 8.1 | |
| Quick Ratio | 0.7 | 0.5 | · | 1.1 | 0.8 | 1.1 | |
| Debt / Equity | 0.2 | 0.1 | · | 0.0 | 0.0 | 0.0 | |
| LT Debt / Equity | 0.1 | 0.1 | · | 0.0 | 0.0 | 0.0 |
Efficiency 3
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | |
| Inventory Turnover | 0.2 | 0.6 | · | · | · | · | |
| Receivables Turnover | 3.0 | 0.6 | · | 1.2 | 6.7 | 0.6 |
Valuation (TTM) 14
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Revenue TTM | $75M | $68M | · | · | · | · | |
| Net Income TTM | $-282M | $-271M | · | $-252M | $-229M | $-212M | |
| Market Cap | $976M | $722M | · | $770M | $501M | $533M | |
| Enterprise Value | $915M | $692M | · | $684M | $428M | $491M | |
| P/E | -3.4 | -2.6 | · | -3.1 | -2.2 | -2.7 | |
| P/S | 13.0 | 10.5 | · | · | · | · | |
| P/B | 20.1 | 6.7 | · | 3.2 | 1.6 | 1.5 | |
| P / Tangible Book | 20.1 | 6.7 | · | 3.2 | 1.6 | 1.5 | |
| P / Cash Flow | · | -8.4 | · | · | · | -7.4 | |
| P / FCF | · | -8.4 | · | · | · | -7.4 | |
| EV / EBITDA | -12.5 | -8.8 | · | -8.6 | -5.9 | -7.6 | |
| EV / FCF | · | -8.1 | · | · | · | -6.8 | |
| EV / Revenue | 12.2 | 10.1 | · | · | · | · | |
| Earnings Yield | -29.2% | -38.0% | · | -32.7% | -45.6% | -37.4% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenue | $67M | $54M | $0 | — | — |
| Operating Margin % | -449.9% | -358.6% | — | — | — |
| Net Income | $-279M | $-174M | $-153M | $-136M | $-130M |
| Diluted EPS | $-3.18 | $-2.02 | $-2.08 | $-2.03 | $-1.97 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Debt / Equity | 0.1 | 0.0 | 0.0 | 0.0 | — |
| Current Ratio | 6.1 | 9.5 | 12.3 | 18.6 | 23.3 |
| Quick Ratio | 1.3 | 2.9 | 1.1 | 2.2 | 4.0 |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Free Cash Flow | $-71M | $134M | $-125M | $-111M | $-106M |
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Institutional owners (13F) 237 filers · $736.0M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 33 (-5 vs prior Q) | 24 (-1 vs prior Q) | 79 (+7 vs prior Q) | 66 (-10 vs prior Q) | +555K |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| MONTANOVA CAPITAL, LLC | $94,072,379 | 8,575,422 | 12.78% | Shares |
| BVF INC/IL | $92,650,086 | 8,445,769 | 12.59% | Shares |
| STATE STREET CORP | $58,461,412 | 5,329,208 | 7.94% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $42,960,319 | 3,916,164 | 5.84% | Shares |
| ARMISTICE CAPITAL, LLC | $40,347,660 | 3,678,000 | 5.48% | Shares |
| ALETHEA CAPITAL MANAGEMENT, LLC | $23,782,280 | 2,167,938 | 3.23% | Shares |
| Prosight Management, LP | $22,180,945 | 2,021,964 | 3.01% | Shares |
| Deep Track Capital, LP | $21,704,858 | 1,978,565 | 2.95% | Shares |
| GOLDMAN SACHS GROUP INC | $21,431,551 | 1,953,651 | 2.91% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $20,956,569 | 1,909,862 | 2.85% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $18,251,502 | 1,663,765 | 2.48% | Shares |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $15,470,717 | 1,410,275 | 2.10% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $14,589,453 | 1,329,941 | 1.98% | Shares |
| NAN FUNG TRINITY (HK) LTD | $12,888,434 | 1,174,880 | 1.75% | Shares |
| Qube Research & Technologies Ltd | $12,833,627 | 1,169,884 | 1.74% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $12,071,125 | 1,100,376 | 1.64% | Shares |
| Connor, Clark & Lunn Investment Management Ltd. | $10,922,500 | 995,670 | 1.48% | Shares |
| BANK OF AMERICA CORP /DE/ | $10,773,889 | 982,123 | 1.46% | Shares |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $10,410,245 | 948,974 | 1.41% | Shares |
| MILLENNIUM MANAGEMENT LLC | $7,803,312 | 711,332 | 1.06% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7,420,108 | 676,400 | 1.01% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $6,906,273 | 629,560 | 0.94% | Shares |
| Fisher Asset Management, LLC | $6,866,520 | 625,936 | 0.93% | Shares |
| ROYCE & ASSOCIATES LP | $6,691,535 | 609,985 | 0.91% | Shares |
| Rhenman & Partners Asset Management AB | $6,488,755 | 591,500 | 0.88% | Shares |
| BlackRock, Inc. | $5,984,201 | 545,506 | 0.81% | Shares |
| JUPITER ASSET MANAGEMENT LTD | $5,593,449 | 509,886 | 0.76% | Shares |
| 1492 Capital Management LLC | $5,124,668 | 467,153 | 0.70% | Shares |
| SECTOR GAMMA AS | $4,750,142 | 433,012 | 0.65% | Shares |
| Man Group plc | $4,749,001 | 432,908 | 0.65% | Shares |
| IEQ CAPITAL, LLC | $3,818,934 | 348,125 | 0.52% | Shares |
| Susquehanna Portfolio Strategies, LLC | $3,772,484 | 343,891 | 0.51% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3,526,855 | 321,500 | 0.48% | Call option |
| MORGAN STANLEY | $3,302,798 | 301,075 | 0.45% | Shares |
| FMR LLC | $3,263,553 | 297,498 | 0.44% | Shares |
| SPHERA FUNDS MANAGEMENT LTD. | $3,236,578 | 295,039 | 0.44% | Shares |
| OP Asset Management Ltd | $3,201,924 | 291,880 | 0.44% | Shares |
| Ally Bridge Group (NY) LLC | $3,181,300 | 290,000 | 0.43% | Shares |
| Ishara Investments LP | $3,035,948 | 276,750 | 0.41% | Shares |
| Assenagon Asset Management S.A. | $2,937,196 | 267,748 | 0.40% | Shares |
| CITADEL ADVISORS LLC | $2,885,615 | 263,046 | 0.39% | Shares |
| GREAT LAKES ADVISORS, LLC | $2,811,918 | 256,328 | 0.38% | Shares |
| PRUDENTIAL FINANCIAL INC | $2,419,434 | 220,550 | 0.33% | Shares |
| Quantinno Capital Management LP | $2,267,817 | 206,728 | 0.31% | Shares |
| AMERIPRISE FINANCIAL INC | $2,226,449 | 202,958 | 0.30% | Shares |
| Trexquant Investment LP | $2,015,529 | 183,731 | 0.27% | Shares |
| TWO SIGMA INVESTMENTS, LP | $1,838,364 | 167,581 | 0.25% | Shares |
| Swedbank AB | $1,677,313 | 152,900 | 0.23% | Shares |
| Mariner, LLC | $1,626,381 | 148,257 | 0.22% | Shares |
| Woodline Partners LP | $1,598,373 | 145,704 | 0.22% | Shares |
| Swiss National Bank | $1,597,232 | 145,600 | 0.22% | Shares |
| TWO SIGMA ADVISERS, LP | $1,585,514 | 152,600 | 0.22% | Shares |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $1,573,564 | 159,724 | 0.21% | Shares |
| BARCLAYS PLC | $1,547,033 | 141,024 | 0.21% | Shares |
| Engineers Gate Manager LP | $1,467,216 | 133,748 | 0.20% | Shares |
| MARTINGALE ASSET MANAGEMENT L P | $1,413,946 | 128,892 | 0.19% | Shares |
| Virtus Investment Advisers, LLC | $1,409,590 | 128,495 | 0.19% | Shares |
| Corient Private Wealth LP | $1,343,727 | 122,491 | 0.18% | Shares |
| CITIGROUP INC | $1,336,552 | 121,837 | 0.18% | Shares |
| DAFNA Capital Management LLC | $1,322,631 | 120,568 | 0.18% | Shares |
| RHUMBLINE ADVISERS | $1,190,674 | 108,540 | 0.16% | Shares |
| Rosalind Advisors, Inc. | $1,097,000 | 100,000 | 0.15% | Shares |
| HSBC HOLDINGS PLC | $1,055,235 | 94,810 | 0.14% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $1,045,112 | 95,270 | 0.14% | Shares |
| AMERICAN CENTURY COMPANIES INC | $1,033,352 | 94,198 | 0.14% | Shares |
| Rangeley Capital, LLC | $1,031,180 | 94,000 | 0.14% | Shares |
| CWM, LLC | $1,005,567 | 123,686 | 0.14% | Shares |
| Xcel Wealth Management, LLC | $998,084 | 90,983 | 0.14% | Shares |
| ALPS ADVISORS INC | $988,320 | 90,093 | 0.13% | Shares |
| ACT CAPITAL MANAGEMENT, LLC | $975,233 | 88,900 | 0.13% | Shares |
| Rafferty Asset Management, LLC | $937,781 | 85,486 | 0.13% | Shares |
| MERCER GLOBAL ADVISORS INC /ADV | $873,082 | 79,588 | 0.12% | Shares |
| Bank of New York Mellon Corp | $821,894 | 74,922 | 0.11% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $815,312 | 74,322 | 0.11% | Shares |
| Jain Global LLC | $798,945 | 72,830 | 0.11% | Shares |
| SECTORAL ASSET MANAGEMENT INC | $784,136 | 71,480 | 0.11% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $774,927 | 95,317 | 0.11% | Shares |
| CITADEL ADVISORS LLC | $759,124 | 69,200 | 0.10% | Call option |
| Aaron Wealth Advisors LLC | $739,981 | 67,455 | 0.10% | Shares |
| Nebula Research & Development LLC | $703,271 | 121,884 | 0.10% | Shares |
| ALLIANCEBERNSTEIN L.P. | $689,424 | 84,800 | 0.09% | Shares |
| JANE STREET GROUP, LLC | $644,586 | 58,759 | 0.09% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $626,859 | 57,143 | 0.09% | Shares |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $621,341 | 56,640 | 0.08% | Shares |
| Pale Fire Capital SE | $620,902 | 56,600 | 0.08% | Shares |
| Quadrature Capital Ltd | $611,183 | 55,714 | 0.08% | Shares |
| Cubist Systematic Strategies, LLC | $611,004 | 69,040 | 0.08% | Shares |
| Knott David M Jr | $578,854 | 52,767 | 0.08% | Shares |
| MetLife Investment Management, LLC | $546,986 | 49,862 | 0.07% | Shares |
| FOX RUN MANAGEMENT, L.L.C. | $543,158 | 49,513 | 0.07% | Shares |
| STATE OF WISCONSIN INVESTMENT BOARD | $540,536 | 49,274 | 0.07% | Shares |
| Lion Point Capital, LP | $504,620 | 46,000 | 0.07% | Shares |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $500,682 | 45,641 | 0.07% | Shares |
| CITADEL ADVISORS LLC | $485,971 | 44,300 | 0.07% | Put option |
| TUDOR INVESTMENT CORP ET AL | $477,414 | 43,520 | 0.06% | Shares |
| PROFUND ADVISORS LLC | $475,506 | 43,346 | 0.06% | Shares |
| SEI INVESTMENTS CO | $440,640 | 40,175 | 0.06% | Shares |
| ADAR1 Capital Management, LLC | $438,800 | 40,000 | 0.06% | Shares |
| AlphaQuest LLC | $438,302 | 42,185 | 0.06% | Shares |
| VANGUARD GROUP INC | $410,592 | 39,518 | 0.06% | Shares |
Company insiders 30 insiders · 19 officers · 11 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Marc Grasso | CFO, CBO | Jan. 26, 2022 A | 21,900 | 0 | 0 | $0 |
| Heidi Henson | Chief Financial Officer | Jan. 24, 2018 A | — | 0 | 0 | $0 |
| Matthew P Kinley | Secretary, CFO | March 6, 2015 D | 0 | 0 | 0 | $0 |
| John Pappajohn | President | March 6, 2015 D | 0 | 0 | 0 | $0 |
| Kathleen Ford | Chief Operating Officer | May 19, 2026 S | 153,560 | 0 | 4 | $-174,610 |
| John Farnam | Chief Operating Officer | Jan. 22, 2019 A | — | 0 | 0 | $0 |
| Mollie Leoni | Chief Medical Officer | June 18, 2026 S | 182,345 | 0 | 7 | $-1,186,414 |
| Brian T. Powl | Chief Commercial Officer | May 21, 2026 S | 173,614 | 0 | 6 | $-346,227 |
| Teresa Brophy Bair | Chief Legal Officer | May 18, 2026 S | 226,931 | 0 | 6 | $-293,126 |
| Francis Burrows | Chief Scientific Officer | Jan. 27, 2026 S | 32,424 | 0 | 2 | $-243,131 |
| Thomas James Doyle | SVP, Finance & Accounting | Jan. 27, 2026 S | 145,167 | 0 | 7 | $-151,764 |
| Stephen Dale | Chief Medical Officer | Jan. 30, 2024 S | 38,817 | 0 | 0 | $0 |
| Kirsten Flowers | CCO & Chief Strategy Officer | Jan. 27, 2023 S | 20,605 | 0 | 0 | $0 |
| James Basta | Chief Legal Officer | Jan. 26, 2021 A | — | 0 | 0 | $0 |
| Bridget A Martell | Acting Chief Medical Officer | Feb. 10, 2020 A | — | 0 | 0 | $0 |
| Antonio Gualberto | Head of Development & CMO | July 10, 2019 M | 339,973 | 0 | 0 | $0 |
| Pingda Ren | SVP Chemistry&Pharma Sciences | Jan. 22, 2019 A | — | 0 | 0 | $0 |
| Annette North | SVP, General Counsel | Jan. 22, 2019 A | — | 0 | 0 | $0 |
| Yi Liu | Chief Scientific Officer | Jan. 24, 2018 A | — | 0 | 0 | $0 |
| Diane L. Parks | Director | June 4, 2026 A | — | 0 | 0 | $0 |
| Michael Vasconcelles | Director | June 4, 2026 A | — | 0 | 0 | $0 |
| Helen Louise Collins | Director | June 4, 2026 A | — | 0 | 0 | $0 |
| Mary T Szela | Director | June 4, 2026 A | — | 0 | 0 | $0 |
| Thomas Malley | Director | June 4, 2026 A | 10,000 | 0 | 0 | $0 |
| Faheem Hasnain | Director | June 4, 2026 A | 23,983 | 0 | 1 | $-109,800 |
| Carol Schafer | Director | June 4, 2026 A | — | 0 | 0 | $0 |
| Steven H Stein | Director | June 21, 2022 A | — | 0 | 0 | $0 |
| Robert Hoffman | Director | June 22, 2021 A | — | 0 | 0 | $0 |
| Argyris Vassiliou | 10% owner | March 6, 2015 D | 0 | 0 | 0 | $0 |
| Troy Edward Wilson | — | Aug. 17, 2026 P | 379,194 | 1 | 1 | $784,662 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 3 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Undisclosed reporting person | April 4, 2008 | — | Initial filing | — | SEC |
| Undisclosed reporting person | April 4, 2008 | — | Initial filing | — | SEC |
| Argyris Vassiliou | April 4, 2008 | — | Initial filing | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership Held by 45 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| BBP · ETFis Series Trust I | 1.38% | 92,599 NS | April 30, 2026 | N-PORT |
| SBIO · ALPS ETF Trust | 0.57% | 91,050 NS | May 31, 2026 | N-PORT |
| HAPS · Harbor ETF Trust | 0.31% | 55,872 NS | April 30, 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0.25% | 144,395 NS | April 30, 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0.08% | 75,402 NS | May 31, 2026 | N-PORT |
| GINN · Goldman Sachs ETF Trust | 0.07% | 13,569 NS | May 31, 2026 | N-PORT |
| BIB · ProShares Trust | 0.04% | 3,218 NS | May 31, 2026 | N-PORT |
| RSSL · Global X Funds | 0.02% | 34,913 NS | April 30, 2026 | N-PORT |
| ITWO · ProShares Trust | 0.02% | 3,795 NS | May 31, 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0.02% | 413,820 NS | May 31, 2026 | N-PORT |
| UWM · ProShares Trust | 0.01% | 2,968 NS | May 31, 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0.01% | 34,421 NS | April 30, 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0.01% | 166,511 NS | April 30, 2026 | N-PORT |
| URTY · ProShares Trust | 0.01% | 3,003 NS | May 31, 2026 | N-PORT |
| TILT · FlexShares Trust | 0.01% | 12,094 NS | April 30, 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0.00% | 2,660 NS | May 31, 2026 | N-PORT |
| HDG · ProShares Trust | 0.00% | 75 NS | May 31, 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0.00% | 154,436 NS | April 30, 2026 | N-PORT |
| AVSU · AMERICAN CENTURY ETF TRUST | 0.00% | 1,215 NS | May 31, 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0.00% | 7,459 NS | April 30, 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0.00% | 15,106 NS | April 30, 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0.00% | 47,582 NS | May 31, 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0.00% | 20,425 NS | April 30, 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0.00% | 222 NS | April 30, 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0.00% | 861 NS | May 31, 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | July 15, 2026 | Daily |
| VTI · VANGUARD INDEX FUNDS | — | — | July 15, 2026 | Daily |
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | July 15, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | — | — | July 15, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | — | — | July 15, 2026 | Daily |
| ITOT · iShares Trust | — | — | Aug. 5, 2026 | Daily |
| IWV · iShares Trust | — | — | Aug. 18, 2026 | Daily |
| IWO · iShares Trust | — | — | Aug. 18, 2026 | Daily |
| IWM · iShares Trust | — | — | Aug. 18, 2026 | Daily |
| IBB · iShares Trust | — | — | Aug. 18, 2026 | Daily |
| PRFZ · Invesco Exchange-Traded Fund Trust | — | — | July 13, 2026 | Daily |
| VHT · VANGUARD WORLD FUND | — | — | July 20, 2026 | Daily |
| ISCB · iShares Trust | — | — | Aug. 5, 2026 | Daily |
| ISCV · iShares Trust | — | — | Aug. 5, 2026 | Daily |
| SMLF · iShares Trust | — | — | Aug. 10, 2026 | Daily |
| SMMV · iShares Trust | — | — | Aug. 18, 2026 | Daily |
| IDNA · iShares Trust | — | — | Aug. 12, 2026 | Daily |
| TECB · iShares Trust | — | — | Aug. 5, 2026 | Daily |
| WSML · iShares Trust | — | — | Aug. 5, 2026 | Daily |
| IBBQ · Invesco Exchange-Traded Fund Trust … | — | — | July 20, 2026 | Daily |