MNKD MannKind Corporation - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$3.90
Price · Aug 18, 2026
Fundamentals as of Aug 5, 2026

About MannKind Corporation - Common Stock Company overview from Wikipedia

MannKind Corporation is a biopharmaceutical company focusing on the discovery, development, and commercialization of therapeutic products for diseases such as diabetes and pulmonary arterial hypertension. Based in Danbury, Connecticut, the company was founded in February 1991.

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MannKind Corporation is a biopharmaceutical company focusing on the discovery, development, and commercialization of therapeutic products for diseases such as diabetes and pulmonary arterial hypertension. Based in Danbury, Connecticut, the company was founded in February 1991.

MannKind Corporation was named after its founder, Alfred E. Mann.

History

Founded in February 1991, the company's present form is a result of a 2003 merger of three companies owned by Alfred E. Mann: Pharmaceutical Discovery Corporation (PDC), the cancer vaccine developer CTL ImmunoTherapies, Inc., and its sister company Allecure Corp, which was developing an allergy vaccine technology. Pharmaceutical Discovery was purchased in 2001 from Solomon Steiner; with that purchase MannKind acquired the Technosphere molecule and Medtone inhaler, upon which was developed its lead product, Afrezza (inhalable insulin).

The FDA approved Afrezza on June 27, 2014.

On August 11, 2014 MannKind entered into an exclusive global licensing agreement with Sanofi for Afrezza sales. Under the agreement, MannKind received $150 million cash from Sanofi, in exchange for sharing profits and losses of sales of Afrezza, with 65% for Sanofi and 35% for MannKind. On January 5, 2016, MannKind Corporation announced the termination of the license and collaboration agreement with Sanofi. By December 2017, the company had lost 11% of its trading volume due to the poor sales.

In March 2020, the company announced it was working with fellow pharmaceutical company Immix Biopharma to try to develop an inhalable treatment for acute respiratory distress syndrome, a lung disease.

Products and product candidates

The firm has developed Afrezza a rapid-acting insulin peaking 12 to 15 minutes after inhalation and exiting the body within 2–3 hours. The inhalation technology uses a miniature, breath-powered inhaler in combination with single-use cartridges containing pre-metered doses. Initial pharmacokinetic studies were followed by studies of safety and efficiency involving Technosphere formulations of different therapeutic proteins.

Leadership

Mann was chief executive officer until January 12, 2015 when Hakan Edstrom became CEO and Mann transitioned to executive chairman.

In November 2015, Hakan Edstrom stepped down as CEO and president. Company founder Alfred Mann stepped in as interim CEO on November 19, 2015. In 2016, Matthew Pfeffer was appointed CEO of MannKind, and served as both CEO and CFO. In May 2017, Michael Castagna was named CEO of the company.

Facilities

MannKind has a large corporate office in Westlake Village, California. The Afrezza manufacturing facility is in Danbury, Connecticut. In 2022, the company moved its official headquarters to Danbury.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

MNKD Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$3.90
Market Cap
$1.20B
P/E (TTM)
194.8
EPS (TTM)
$0.02
Revenue (TTM)
$349M
Div Yield
ROE
-11.1%
Debt/Equity
52W Range
$2 – $7

MNKD Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $349M
10-point trend, +99.7%
2016-12-31 2025-12-31
EPS $0.02
9-point trend, -98.5%
2016-12-31 2025-12-31
Free Cash Flow $14M
8-point trend, +135.9%
2018-12-31 2025-12-31
Margins 1.7%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
MNKD
Peer Median
P/E (TTM)
5-point trend, +2176.0%
194.8
P/S (TTM)
5-point trend, -65.7%
3.4
10.7
P/B
5-point trend, -551.7%
-23.5
5.2
Price / FCF
5-point trend, +949.0%
87.6

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
MNKD
Peer Median
Operating Margin
5-point trend, +117.8%
11.1%
Net Profit Margin
5-point trend, +101.6%
1.7%
-140.3%
ROA
5-point trend, +102.6%
0.99%
-44.7%
ROE
5-point trend, -126.9%
-11.1%
-51.5%
ROIC
5-point trend, -1510.9%
-316.9%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
MNKD
Peer Median
Current Ratio
5-point trend, -62.5%
1.7
9.5
Quick Ratio
5-point trend, -71.6%
1.2

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
MNKD
Peer Median
Revenue YoY
5-point trend, +362.6%
22.2%
Revenue CAGR 3Y
5-point trend, +362.6%
51.8%
Revenue CAGR 5Y
5-point trend, +362.6%
39.9%
EPS YoY
5-point trend, +106.2%
-80.0%
Net Income YoY
5-point trend, +107.2%
-78.8%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
MNKD
Peer Median
EPS (Diluted)
5-point trend, +106.2%
$0.02

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
MNKD
Peer Median

MNKD Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 14 analysts
  • Strong Buy 4 28.6%
  • Buy 8 57.1%
  • Hold 2 14.3%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

8 analysts · 2026-08-17
Median target $7.50 +92.6%
Mean target $7.97 +104.6%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.03%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.06 $-0.00 -0.06%
March 31, 2026 $-0.05 $-0.00 -0.05%
Dec. 31, 2025 $-0.05 $0.01 -0.06%
Sept. 30, 2025 $0.07 $0.02 0.05%
June 30, 2025 $0.00 $0.05 -0.05%
March 31, 2025 $0.04 $0.04 -0.00%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
MNKD $1.75B 283.5 22.2% 1.7% -11.1%
NVAX $1.09B 2.6 64.7% 39.2% -977.1%
INBX $1.15B -8.7 550.0% -10773.5% -365.9%
GLUE $1.03B 63.5% -31.2% -15.4%
MGTX $645M -5.6 144.6% -140.3% 8062.2%
CRVS $575M -14.5 -21.6%
REPL $633M -2.3 -146.2%
VOR $506M -0.2 83.4%
SANA $1.09B -4.2 -172.3%
SVRA $1.23B -11.4 -73.4%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 16
Annual Income Statement data for MNKD
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +348966000.00 $349M $286M $199M $100M $75M $65M $63M $28M $12M $175M $0 $0
Cost of Revenue 11-point trend, -58.6% $27M $17M $21M $16M $17M $15M $20M $19M $17M $17M $65M ·
SG&A Expense 12-point trend, +81.6% $144M $94M $94M $91M $32M $25M $75M $80M $75M $47M $41M $79M
Operating Expenses 12-point trend, -51.0% $88M $77M $63M $57M $39M $25M $108M $104M $120M $107M $345M $180M
Operating Income 12-point trend, +121.6% $39M $73M $9M $-64M $-47M $-48M $-45M $-77M $-108M $67M $-345M $-180M
Interest Expense 5-point trend, -25.7% · · $15M $15M $15M · · · · · $24M $20M
Interest Income 12-point trend, +89377.8% $8M $13M $6M $3M $112.0K $167.0K $997.0K $501.0K $293.0K $85.0K $18.0K $9.0K
Other Non-op 12-point trend, -160.1% $-1M $32.0K $122.0K $-102.0K $-239.0K $23.0K $-926.0K $-437.0K $13.0K $-597.0K $1M $2M
Pretax Income 12-point trend, +100.7% $1M $31M $-10M $-87M $-81M $-57M $-52M $-87M $-117M $126M $-368M $-198M
Income Tax 12-point trend, -4456000.00 $-4M $3M $2M $0 $0 $-218.0K $0 $240.0K $51.0K $0 $0 $0
Net Income 12-point trend, +103.0% $6M $28M $-12M $-87M $-81M $-57M $-52M $-87M $-117M $126M $-368M $-198M
EPS (Basic) 11-point trend, +100.8% $0.02 $0.10 $-0.04 $-0.34 $-0.32 $-0.26 · $-0.60 $-1.13 $1.37 $-4.54 $-2.57
EPS (Diluted) 11-point trend, +100.8% $0.02 $0.10 $-0.04 $-0.34 $-0.32 $-0.26 · $-0.60 $-1.13 $1.36 $-4.54 $-2.57
Shares (Basic) 11-point trend, +296.7% 305,639,000 274,415,000 267,014,000 257,092,000 249,244,000 222,585,000 · 144,136,000 104,245,000 92,053,000 81,233,000 77,045,000
Shares (Diluted) 11-point trend, +307.7% 314,112,000 283,844,000 267,014,000 257,092,000 249,244,000 222,585,000 · 144,136,000 104,245,000 92,085,000 81,233,000 77,045,000
EBITDA 11-point trend, +122.8% $39M $73M $9M $-64M $-47M $-48M $-45M $-77M $-106M · $-334M $-170M
Balance Sheet 28
Annual Balance Sheet data for MNKD
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, -38.0% $75M $46M $238M $70M $124M $67M $30M $71M $44M $23M $59M $121M
Short-term Investments 7-point trend, +382.9% $96M $151M $57M $101M $80M $0 $20M · · · · ·
Receivables 12-point trend, -23.9% $38M $12M $15M $17M $5M $4M $4M $4M $3M $302.0K $23.0K $50M
Inventory 11-point trend, +265.2% $35M $28M $29M $22M $7M $5M $4M $4M $3M $2M · $10M
Prepaid Expense 12-point trend, +130.4% $47M $31M $35M $25M $3M $3M $3M $3M $3M $4M $4M $20M
Current Assets 12-point trend, +45.0% $292M $268M $373M $235M $219M $79M $61M $82M $57M $77M $77M $201M
PP&E (Net) 12-point trend, -57.1% $82M $85M $84M $45M $37M $26M $27M $26M $27M $29M $49M $192M
PP&E (Gross) 12-point trend, -36.7% $196M $192M $186M $144M $134M $123M $122M $126M $128M $129M $168M $310M
Accum. Depreciation 12-point trend, -3.6% $114M $107M $102M $99M $98M $97M $95M $100M $101M $100M $120M $118M
Goodwill 4-point trend, +2684.0% $68M $2M $2M $2M · · · · · · · ·
Intangibles 4-point trend, +339.9% $5M $5M $1M $1M · · · · · · · ·
Other Non-current Assets 12-point trend, +2273.7% $20M $27M $7M $10M $8M $3M $6M $249.0K $437.0K $648.0K $1M $848.0K
Total Assets 12-point trend, +100.8% $792M $394M $475M $295M $321M $109M $94M $108M $85M $107M $126M $394M
Accounts Payable 12-point trend, +22.2% $9M $7M $10M $11M $7M $6M $5M $5M $7M $3M $16M $7M
Accrued Liabilities 12-point trend, +146.6% $65M $40M $42M $36M $27M $20M $16M $15M $12M $8M $8M $26M
Short-term Debt · · · · · · $5M · · · · ·
Current Liabilities 12-point trend, -57.6% $171M $82M $104M $67M $48M $74M $66M $75M $88M $92M $268M $403M
Capital Leases 7-point trend, +325.2% $11M $12M $4M $5M $1M $1M $3M · · · · ·
Other Non-current Liabilities 3-point trend, -59.8% · · · · $5M · · · · · $15M $12M
Total Liabilities 12-point trend, +80.1% $843M $473M $721M $546M $531M $289M $284M $283M $299M $291M $477M $468M
Long-term Debt 9-point trend, +126.1% $355M $36M $269M $273M $281M $122M $119M $102M $157M · · ·
Total Debt · · · · · · $5M · · · · ·
Common Stock 12-point trend, -24.2% $3M $3M $3M $3M $3M $2M $2M $2M $1M $957.0K $4M $4M
Retained Earnings 12-point trend, -28.1% $-3.20B $-3.20B $-3.23B $-3.22B $-3.13B $-3.05B $-2.99B $-2.94B $-2.85B $-2.74B $-2.86B $-2.49B
AOCI 8-point trend, +921.4% $115.0K $1M · · · · $-19.0K $-19.0K $-18.0K $-24.0K $-20.0K $-14.0K
Stockholders' Equity 12-point trend, +30.8% $-51M $-79M $-246M $-251M $-209M $-180M $-191M $-175M $-215M $-184M $-350M $-74M
Liabilities + Equity 12-point trend, +100.8% $792M $394M $475M $295M $321M $109M $94M $108M $85M $107M $126M $394M
Shares Outstanding 12-point trend, -24.2% 307,832,587 302,959,782 270,034,495 263,793,305 251,477,562 242,117,089 211,787,573 187,029,967 119,053,414 95,680,831 85,734,188 406,059,089
Cash Flow 18
Annual Cash Flow data for MNKD
Metric Trend 202520242023202220212020201920182017201620152014
D&A 12-point trend, +25.3% $12M $7M $5M $3M $2M $2M $972.0K $3M $2M $2M $11M $10M
Stock-based Comp 12-point trend, -50.2% $24M $21M $18M $13M $12M $7M $6M $7M $5M $5M $9M $49M
Deferred Tax 12-point trend, +70.3% $-19M $4M $7M $-10M $-20M $-5M $-5M $-11M $-260M $48M $-80M $-66M
Amort. of Intangibles $4M · · · · · · · · · · ·
Restructuring 3-point trend, +7.1% · · · · · · · · · $2M $6M $2M
Other Non-cash 3-point trend, +112.5% · · · · · · · · $306M · $291M $144M
Operating Cash Flow 12-point trend, +346.8% $18M $43M $34M $-81M $-62M $-28M $-88M $-38M $-65M $-78M $-57M $4M
CapEx 11-point trend, -81.1% $5M $10M $42M $8M $11M $801.0K $3M $354.0K · $1M $10M $24M
Investing Cash Flow 10-point trend, -26945.5% $-305M $-97M $-2M $5M $-152M $15M $-23M $-234.0K $17M $-1M · ·
Debt Issued 2-point trend, -75.6% · · · · · $5M · · · · · $20M
Net Debt Issued · · · · · $5M · · · · · ·
Stock Issued 3-point trend, -98.0% · · · · · · · · $564.0K $893.0K $28M ·
Net Stock Activity 2-point trend, -98.0% · · · · · · · · $564.0K · $28M ·
Financing Cash Flow 10-point trend, +632.1% $315M $-137M $137M $21M $270M $50M $70M $61M $74M $43M · ·
Net Change in Cash 12-point trend, -43.0% $29M $-191M $169M $-54M $57M $37M $-41M $23M $25M $-36M $-62M $50M
Taxes Paid 2-point trend, -60.0% $2M $4M · · · · · · · · · ·
Free Cash Flow 10-point trend, +168.4% $14M $33M $-8M $-88M $-73M $-29M $-91M $-38M · · $-68M $-20M
Levered FCF 3-point trend, +71.9% · · $-26M $-98M · · · · · · $-92M ·
Profitability 7
Annual Profitability data for MNKD
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 9-point trend, +101.2% 11.1% 25.4% 4.4% -64.3% -62.3% -73.6% -70.8% -274.9% -921.1% · · ·
Net Margin 9-point trend, +100.2% 1.7% 9.7% -6.0% -87.6% -107.3% -87.9% -82.3% -312.2% -999.0% · · ·
Pretax Margin 9-point trend, +100.0% 0.40% 10.7% -5.2% -87.6% -107.3% -88.2% -82.3% -311.3% -998.6% · · ·
EBITDA Margin 9-point trend, +101.2% 11.1% 25.4% 4.4% -64.3% -62.3% -73.6% -70.8% -274.9% -905.8% · · ·
ROA 11-point trend, +101.6% 0.99% 6.3% -3.1% -28.4% -37.7% -56.6% -51.5% -90.5% -122.4% · -141.5% -60.8%
ROE 11-point trend, -102.9% -11.1% -19.1% 4.8% 35.8% 41.1% 31.2% 27.7% 45.7% 58.9% · 173.8% 379.7%
ROIC 10-point trend, -422.1% -316.9% -83.2% -4.1% 25.6% 22.5% 26.5% 24.0% 43.9% 50.4% · 98.4% ·
Liquidity & Solvency 4
Annual Liquidity & Solvency data for MNKD
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, +241.8% 1.7 3.3 3.6 3.5 4.5 1.1 0.9 1.1 0.7 · 0.3 0.5
Quick Ratio 11-point trend, +188.8% 1.2 2.6 3.0 2.8 4.3 1.0 0.8 1.0 0.5 · 0.2 0.4
Debt / Equity · · · · · · -0.0 · · · · ·
Interest Coverage 4-point trend, +106.5% · · 0.6 -6.7 · · · · · · -14.3 -8.8
Efficiency 3
Annual Efficiency data for MNKD
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 10-point trend, +0.59 0.6 0.7 0.5 0.3 0.4 0.6 0.6 0.3 0.1 · 0.0 ·
Inventory Turnover 9-point trend, -87.7% 0.8 0.6 0.8 1.1 2.8 3.3 5.2 6.2 6.9 · · ·
Receivables Turnover 10-point trend, +13.91 13.9 21.4 12.6 9.3 16.4 16.9 16.7 8.2 7.6 · 0.0 ·
Per Share 5
Annual Per Share data for MNKD
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 11-point trend, +8.8% $-0.17 $-0.26 $-0.91 $-0.95 $-0.83 $-0.75 $-0.90 $-0.94 $-1.80 · $-0.82 $-0.18
Revenue / Share 6-point trend, +885.8% $1.11 $1.01 $0.75 $0.39 · · · $0.19 $0.11 · · ·
Cash Flow / Share 6-point trend, +109.3% $0.06 $0.15 $0.13 $-0.31 · · · $-0.26 $-0.62 · · ·
Cash / Share 11-point trend, -18.2% $0.24 $0.15 $0.88 $0.26 $0.49 $0.28 $0.14 $0.38 $0.37 · $0.14 $0.30
EPS (TTM) 12-point trend, +100.8% $0.02 $0.10 $-0.04 $-0.34 $-0.32 $-0.26 $-0.63 $-0.60 $-1.13 $1.36 $-4.54 $-2.57
Growth Rates 5
Annual Growth Rates data for MNKD
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +40.6% 22.2% 43.5% 99.4% 32.2% 15.8% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +14.9% 51.8% 55.8% 45.1% · · · · · · · · ·
Revenue CAGR 5Y 39.9% · · · · · · · · · · ·
EPS YoY -80.0% · · · · · · · · · · ·
Net Income YoY -78.8% · · · · · · · · · · ·
Valuation (TTM) 13
Annual Valuation (TTM) data for MNKD
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +348966000.00 $349M $286M $199M $100M $75M $65M $63M $28M $12M $175M $0 $0
Net Income TTM 12-point trend, +103.0% $6M $28M $-12M $-87M $-81M $-57M $-52M $-87M $-117M $126M $-368M $-198M
Market Cap 11-point trend, -83.5% $1.75B $1.95B $983M $1.39B $1.10B $758M $273M $198M $276M · $3.11B $10.60B
Enterprise Value · · · · · · $228M · · · · ·
P/E 12-point trend, +2891.6% 283.5 64.3 -91.0 -15.5 -13.7 -12.0 -2.0 -1.8 -2.1 2.4 -1.6 -10.2
P/S 9-point trend, -78.7% 5.0 6.8 4.9 13.9 14.6 11.6 4.3 7.1 23.5 · · ·
P/B 11-point trend, +76.2% -34.2 -24.7 -4.0 -5.5 -5.2 -4.2 -1.4 -1.1 -1.3 · -8.9 -143.7
P / Cash Flow 11-point trend, -96.3% 95.6 45.8 28.8 -17.2 -17.8 -26.9 -3.1 -5.3 -4.3 · -54.3 2593.8
P / FCF 10-point trend, +124.1% 127.5 59.4 -117.8 -15.7 -15.0 -26.2 -3.0 -5.2 · · -46.0 -529.6
EV / EBITDA · · · · · · -5.1 · · · · ·
EV / FCF · · · · · · -2.5 · · · · ·
EV / Revenue · · · · · · 3.6 · · · · ·
Earnings Yield 12-point trend, +103.6% 0.35% 1.6% -1.1% -6.5% -7.3% -8.3% -48.8% -56.6% -48.7% 42.5% -62.6% -9.8%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $349M$286M$199M$100M$75M
Operating Margin % 11.1%25.4%4.4%-64.3%-62.3%
Net Income $6M$28M$-12M$-87M$-81M
Diluted EPS $0.02$0.10$-0.04$-0.34$-0.32
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 1.73.33.63.54.5
Quick Ratio 1.22.63.02.84.3
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $14M$33M$-8M$-88M$-73M

Latest News Recent headlines mentioning this company

Trading Signals Recent buy/sell signals with entry price and risk/reward ratio

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Institutional owners (13F) 271 filers · $560.6M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
55 (+12 vs prior Q) 37 (-11 vs prior Q) 93 (+10 vs prior Q) 61 (-8 vs prior Q) +24.2M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Rubric Capital Management LP $76,680,000 18,000,000 13.68% Shares
STATE STREET CORP $68,901,423 16,174,043 12.29% Shares
VANGUARD CAPITAL MANAGEMENT LLC $56,101,610 13,169,392 10.01% Shares
GEODE CAPITAL MANAGEMENT, LLC $29,027,881 6,812,460 5.18% Shares
Frazier Life Sciences Management, L.P. $28,116,000 6,600,000 5.01% Shares
Deep Track Capital, LP $25,560,000 6,000,000 4.56% Shares
WELLINGTON MANAGEMENT GROUP LLP $23,099,232 5,422,355 4.12% Shares
180 WEALTH ADVISORS, LLC $21,126,835 4,959,351 3.77% Shares
FMR LLC $17,455,563 4,097,550 3.11% Shares
TSP Capital Management Group, LLC $16,923,596 3,972,675 3.02% Shares
BRAIDWELL LP $14,732,908 3,458,429 2.63% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $12,789,240 3,002,169 2.28% Shares
VANGUARD GROUP INC $11,888,249 2,096,693 2.12% Shares
TWO SIGMA INVESTMENTS, LP $11,475,213 2,693,712 2.05% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $11,070,577 2,598,727 1.97% Shares
VANGUARD FIDUCIARY TRUST CO $9,358,279 2,196,779 1.67% Shares
BANK OF AMERICA CORP /DE/ $8,689,749 2,039,847 1.55% Shares
GOLDMAN SACHS GROUP INC $6,332,618 1,486,530 1.13% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $5,030,221 1,180,803 0.90% Shares
BlackRock, Inc. $4,766,748 1,118,955 0.85% Shares
DIMENSIONAL FUND ADVISORS LP $4,486,321 1,053,127 0.80% Shares
Caption Management, LLC $4,260,000 1,000,000 0.76% Put option
J. Goldman & Co LP $3,478,669 816,589 0.62% Shares
WELLS FARGO & COMPANY/MN $3,473,987 815,490 0.62% Shares
SCOPIA CAPITAL MANAGEMENT LP $2,960,534 694,961 0.53% Shares
Balyasny Asset Management L.P. $2,914,296 684,107 0.52% Shares
TWO SIGMA ADVISERS, LP $2,897,166 510,964 0.52% Shares
VICTORY CAPITAL MANAGEMENT INC $2,771,407 650,565 0.49% Shares
Swiss National Bank $2,502,324 587,400 0.45% Shares
STATE OF WISCONSIN INVESTMENT BOARD $2,177,052 511,045 0.39% Shares
JACOBS LEVY EQUITY MANAGEMENT, INC $2,106,540 494,493 0.38% Shares
1492 Capital Management LLC $2,052,136 481,722 0.37% Shares
Mariner, LLC $2,020,189 474,236 0.36% Shares
MILLENNIUM MANAGEMENT LLC $1,836,597 431,126 0.33% Shares
Schonfeld Strategic Advisors LLC $1,774,216 416,483 0.32% Shares
Squarepoint Ops LLC $1,759,644 413,062 0.31% Shares
Jefferies Financial Group Inc. $1,694,202 397,700 0.30% Shares
ExodusPoint Capital Management, LP $1,666,261 391,141 0.30% Shares
JANE STREET GROUP, LLC $1,658,418 389,300 0.30% Call option
Man Group plc $1,624,023 381,226 0.29% Shares
RHUMBLINE ADVISERS $1,604,647 376,681 0.29% Shares
IEQ CAPITAL, LLC $1,544,607 362,584 0.28% Shares
CITIGROUP INC $1,499,243 351,935 0.27% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,423,692 334,200 0.25% Put option
Bank of New York Mellon Corp $1,422,222 333,855 0.25% Shares
Caption Management, LLC $1,414,231 331,979 0.25% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $1,359,221 319,066 0.24% Shares
ALPS ADVISORS INC $1,330,615 312,351 0.24% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,216,230 285,500 0.22% Call option
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $1,029,075 241,567 0.18% Shares
BARCLAYS PLC $1,029,062 241,564 0.18% Shares
Rafferty Asset Management, LLC $1,008,640 236,770 0.18% Shares
BNP PARIBAS FINANCIAL MARKETS $1,002,715 235,379 0.18% Shares
Aaron Wealth Advisors LLC $1,000,878 234,948 0.18% Shares
HSBC HOLDINGS PLC $998,560 230,881 0.18% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $930,294 379,712 0.17% Shares
CITADEL ADVISORS LLC $928,680 218,000 0.17% Call option
CITADEL ADVISORS LLC $898,860 211,000 0.16% Put option
Bruce & Co., Inc. $831,011 195,073 0.15% Shares
VANGUARD ASSET MANAGEMENT, Ltd $775,060 181,939 0.14% Shares
MetLife Investment Management, LLC $766,442 179,916 0.14% Shares
FRANKLIN RESOURCES INC $755,021 177,235 0.13% Shares
Stonepine Capital Management, LLC $750,000 250,000 0.13% Call option
UBS Group AG $715,978 168,070 0.13% Shares
ALLIANCEBERNSTEIN L.P. $693,375 283,010 0.12% Shares
MORGAN STANLEY $651,282 152,883 0.12% Shares
TUDOR INVESTMENT CORP ET AL $640,657 150,389 0.11% Shares
RAYMOND JAMES FINANCIAL INC $632,009 148,359 0.11% Shares
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $613,437 171,372 0.11% Shares
Jain Global LLC $604,673 141,942 0.11% Shares
KING LUTHER CAPITAL MANAGEMENT CORP $590,457 138,605 0.11% Shares
Susquehanna Portfolio Strategies, LLC $574,538 134,868 0.10% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $570,354 133,886 0.10% Shares
MERCER GLOBAL ADVISORS INC /ADV $557,723 130,921 0.10% Shares
PROFUND ADVISORS LLC $517,726 121,532 0.09% Shares
Invesco Ltd. $512,389 120,279 0.09% Shares
Vanguard Global Advisers, LLC $509,833 119,679 0.09% Shares
KLP KAPITALFORVALTNING AS $491,604 115,400 0.09% Shares
Gotham Asset Management, LLC $452,463 106,212 0.08% Shares
State of New Jersey Common Pension Fund D $403,171 94,641 0.07% Shares
State of Wyoming $403,149 94,636 0.07% Shares
Police & Firemen's Retirement System of New Jersey $386,834 90,806 0.07% Shares
Amundi $374,310 87,866 0.07% Shares
Zurcher Kantonalbank (Zurich Cantonalbank) $373,478 87,671 0.07% Shares
NEW YORK STATE COMMON RETIREMENT FUND $359,966 84,499 0.06% Shares
ARIZONA STATE RETIREMENT SYSTEM $344,050 80,763 0.06% Shares
Mitsubishi UFJ Asset Management Co., Ltd. $338,155 79,379 0.06% Shares
Aquatic Capital Management LLC $335,300 78,709 0.06% Shares
Rockefeller Capital Management L.P. $332,996 78,168 0.06% Shares
Vanguard Investments Australia, Ltd. $314,929 73,927 0.06% Shares
JANUS HENDERSON GROUP PLC $313,658 127,763 0.06% Shares
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $312,203 73,287 0.06% Shares
Sequoia Financial Advisors, LLC $296,935 69,703 0.05% Shares
INTECH INVESTMENT MANAGEMENT LLC $284,653 66,820 0.05% Shares
COMMONWEALTH EQUITY SERVICES, LLC $280,421 65,827 0.05% Shares
China Universal Asset Management Co., Ltd. $262,714 61,670 0.05% Shares
LPL Financial LLC $260,060 61,047 0.05% Shares
SIMPLEX TRADING, LLC $258,790 60,749 0.05% Shares
Cetera Investment Advisers $241,546 56,701 0.04% Shares
Painted Porch Advisors LLC $227,620 53,432 0.04% Shares

Company insiders 43 insiders · 27 officers · 18 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Michael Castagna Chief Executive Officer July 15, 2026 M 2,433,779 1 4 $-990,292
Hakan Edstrom President & CEO Aug. 27, 2015 A 1,114,340 0 0 $0
Christopher B Prentiss Chief Financial Officer July 15, 2026 F 318,668 0 0 $0
Juergen Martens Corporate VP and COO Aug. 27, 2015 A 106,539 0 0 $0
Dominic Marasco Pres, Endocrine Business Unit July 15, 2026 F 343,398 0 0 $0
Sanjay R Singh EVP Technical Operations July 15, 2026 M 478,966 0 1 $-94,448
Stuart A Tross Chief People & Workpl Officer July 15, 2026 M 1,058,142 0 2 $-548,528
David Thomson EVP Genl Counsel & Secretary July 15, 2026 M 797,554 0 3 $-930,755
Ajay Ahuja Chief Medical Officer March 23, 2026 A 318,200 0 0 $0
Lauren M Sabella EVP Operations July 15, 2025 F 349,841 0 0 $0
Burkhard Blank EVP Chief Medical Officer July 15, 2025 F 460,791 0 0 $0
Joseph Kocinsky Chief Technology Officer Aug. 27, 2022 F 745,233 0 0 $0
Alejandro Galindo EVP Endocrine Business Unit Feb. 28, 2022 A 576,690 0 0 $0
Rosabel Realica Alinaya VP, IR & Treasury Aug. 27, 2020 A 167,119 0 0 $0
David M Kendall Chief Medical Officer July 31, 2020 P 41,059 0 0 $0
Patrick Mccauley Chief Commercial Officer Feb. 25, 2020 A 83,972 0 0 $0
Courtney Barton Chief Compl & Privacy Officer July 31, 2019 P 29,584 0 0 $0
Elizabeth Garrett Ingram Chief Marketing Officer May 14, 2019 A 43,012 0 0 $0
Raymond W. Urbanski Corp VP, CMO Aug. 10, 2017 S 2,924 0 0 $0
Linda A Adreveno Sr. VP, HR Feb. 18, 2016 A 92,200 0 0 $0
Alfred E Mann Executive Chairman Aug. 22, 2015 F 1,005,990 0 0 $0
Diane Palumbo Vice President, Human Resource Feb. 23, 2015 F 50,624 0 0 $0
Peter C Richardson Chief Scientific Officer March 3, 2012 F 133,611 0 0 $0
Richard L Anderson Corporate VP Nov. 16, 2008 F 204,401 0 0 $0
John R. Riesenberger VP & Chief Commercial Officer Aug. 13, 2008 A 14,650 0 0 $0
Dan Burns VP & President, MKBP Dec. 8, 2006 A 14,800 0 0 $0
Wendell W Cheatham VP, Medical & Reg Affairs Aug. 19, 2004 A 300 0 0 $0
Sabrina Kay Director May 20, 2026 A 265,600 0 0 $0
Jennifer Grancio Director May 20, 2026 A 244,815 0 0 $0
James Samuel Shannon Director May 20, 2026 A 64,635 0 0 $0
Michael A Friedman Director May 20, 2026 A 47,500 0 0 $0
Anthony C Hooper Director May 20, 2026 A 236,153 0 0 $0
Christine Mundkur Director May 20, 2026 A 254,493 0 0 $0
Ronald J Consiglio Director May 20, 2026 A 132,342 0 0 $0
Kent Kresa Director May 15, 2024 A 274,541 0 0 $0
Henry L Nordhoff Director May 14, 2019 A 103,426 0 0 $0
David Maccallum Director May 16, 2018 A 114,790 0 0 $0
Matthew J Pfeffer Director Aug. 28, 2017 F 81,961 0 0 $0
Abraham E Cohen Director Aug. 17, 2012 S 56,424 0 0 $0
Heather Hay Murren Director Aug. 13, 2008 A 10,100 0 0 $0
Kathleen Connell Director May 25, 2006 A 0 0 $0
Llew Keltner Director May 25, 2006 A 0 0 $0
Steven B. Binder Aug. 7, 2026 S 785,867 0 3 $-427,369

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 2 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Alfred E. Mann, Alfred E. Mann Living Trust, Biomed Partners, LLC, Minimed Infusion, Inc., The Mann Group LLC ×2 filings July 10, 2012 Initial filing SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Jan. 31, 2006 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 41 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
RNIN · EA Series Trust 1.43% 773,251 NS April 30, 2026 N-PORT
SBIO · ALPS ETF Trust 0.74% 317,578 NS May 31, 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0.54% 29,662 SH Aug. 8, 2026 Daily
AGNG · Global X Funds 0.46% 98,947 NS May 31, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.34% 625,921 NS April 30, 2026 N-PORT
GINN · Goldman Sachs ETF Trust 0.11% 64,525 NS May 31, 2026 N-PORT
IBB · iShares Trust 0.09% 2,170,137 SH Aug. 8, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.09% 16,814 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.08% 330,117 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.07% 2,772,931 SH Aug. 8, 2026 Daily
ESML · iShares Trust 0.06% 449,515 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.06% 11,389 NS May 31, 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.04% 114,273 NS April 30, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.04% 1,771,496 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.04% 7,830,029 SH Aug. 8, 2026 Daily
ISCG · iShares Trust 0.04% 94,032 SH Aug. 8, 2026 Daily
ITWO · ProShares Trust 0.03% 14,400 NS May 31, 2026 N-PORT
RSSL · Global X Funds 0.03% 132,607 NS April 30, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.02% 1,466,402 NS May 31, 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0.02% 61,465 NS May 31, 2026 N-PORT
VHT · VANGUARD WORLD FUND 0.02% 874,372 SH Aug. 8, 2026 Daily
ISCB · iShares Trust 0.02% 13,557 SH Aug. 8, 2026 Daily
UWM · ProShares Trust 0.02% 11,261 NS May 31, 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0.01% 135,688 NS April 30, 2026 N-PORT
DFAS · Dimensional ETF Trust 0.01% 638,128 NS April 30, 2026 N-PORT
URTY · ProShares Trust 0.01% 11,390 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.01% 3,543,398 SH Aug. 8, 2026 Daily
WSML · iShares Trust 0.01% 16,464 SH Aug. 8, 2026 Daily
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.01% 12,000 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.01% 286 NS May 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 452,118 NS April 30, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 27,701 NS April 30, 2026 N-PORT
AVUQ · AMERICAN CENTURY ETF TRUST 0.00% 1,330 NS May 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 465,445 SH Aug. 8, 2026 Daily
SCHB · SCHWAB STRATEGIC TRUST 0.00% 196,006 NS May 31, 2026 N-PORT
IWV · iShares Trust 0.00% 83,220 SH Aug. 8, 2026 Daily
TILT · FlexShares Trust 0.00% 10,345 NS April 30, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 32,093 NS April 30, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.00% 14,557 NS April 30, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 9,327,332 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 26,184 SH Aug. 8, 2026 Daily