ORIC Oric Pharmaceuticals, Inc. - Common Stock
$14.35
Price · Aug 19, 2026
Fundamentals as of Aug 3, 2026
52W Range
$7–$15
92% of range
Analyst Rating
BUY
21 analysts
Price Target
$21
+44% upside
P/E (TTM)
-10.3
ROE
-36.5%
Net Profit Margin
—
ORIC Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$14.35
Market Cap
$1.49B
P/E (TTM)
-10.3
EPS (TTM)
$-1.47
Revenue (TTM)
—
Div Yield
—
ROE
-36.5%
Debt/Equity
—
52W Range
$7 – $15
ORIC Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
Configure
10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
—
EPS
$-1.47
2021-12-31
→
2025-12-31
Free Cash Flow
$-112M
2020-12-31
→
2025-12-31
Margins
—
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
ORIC
Peer Median
P/E (TTM)
-10.3
—
P/B
3.9
3.6
Price / FCF
-13.3
—
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
ORIC
Peer Median
ROA
-37.9%
-40.9%
ROE
-36.5%
-47.9%
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
ORIC
Peer Median
Current Ratio
14.1
8.3
Quick Ratio
2.2
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
ORIC
Peer Median
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
ORIC
Peer Median
ORIC Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
21 analysts
- Strong Buy 9 42.9%
- Buy 10 47.6%
- Hold 2 9.5%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
12 analysts · 2026-08-19
Median
$21.50
Now
$14.35
Low
$14.00
High
$27.00
Median target
$21.50
+49.8%
Mean target
$20.67
+44.0%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
0.04%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| June 30, 2026 | $-0.38 | $-0.37 | -0.01% |
| March 31, 2026 | $-0.34 | $-0.33 | -0.01% |
| Dec. 31, 2025 | $-0.30 | $-0.37 | 0.07% |
| Sept. 30, 2025 | $-0.33 | $-0.41 | 0.08% |
| June 30, 2025 | $-0.47 | $-0.45 | -0.02% |
| March 31, 2025 | $-0.42 | $-0.52 | 0.10% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| ORIC | $806M | -5.6 | — | — | -36.5% | — |
| VIR | $841M | -1.9 | -7.6% | -638.9% | -51.1% | — |
| ABSI | $529M | -4.2 | -38.2% | -4113.7% | -63.5% | — |
| AVBP | $854M | -4.7 | — | — | -59.7% | — |
| PURR | — | — | — | — | — | — |
| AKTS | — | — | — | — | — | — |
| CGEM | $624M | -3.2 | — | — | -44.0% | — |
| NVAX | $1.09B | 2.6 | 64.7% | 39.2% | -977.1% | — |
| INBX | $1.15B | -8.7 | 550.0% | -10773.5% | -365.9% | — |
| GLUE | $1.03B | — | 63.5% | -31.2% | -15.4% | — |
| MGTX | $645M | -5.6 | 144.6% | -140.3% | 8062.2% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 11
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| SG&A Expense | $33M | $29M | $26M | $25M | $22M | $13M | $6M | |
| Operating Expenses | $143M | $143M | $111M | $92M | $79M | $74M | $29M | |
| Operating Income | $-143M | $-143M | $-111M | $-92M | $-79M | $-74M | $-29M | |
| Other Non-op | $14M | $15M | $10M | $3M | $156.0K | $483.0K | $2M | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-129M | $-128M | $-101M | $-89M | $-79M | $-74M | $-27M | |
| EPS (Basic) | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 | · | · | |
| EPS (Diluted) | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 | · | · | |
| Shares (Basic) | 87,793,801 | 69,727,940 | 51,450,848 | 39,655,260 | 37,954,280 | · | · | |
| Shares (Diluted) | 87,793,801 | 69,727,940 | 51,450,848 | 39,655,260 | 37,954,280 | · | · | |
| EBITDA | $-143M | $-143M | $-111M | $-92M | $-79M | $-74M | · |
Balance Sheet 22
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $46M | $59M | $23M | $67M | $226M | $78M | $89M | |
| Short-term Investments | · | · | · | · | · | $215M | · | |
| Prepaid Expense | $7M | $6M | $4M | $4M | $4M | $3M | $840.0K | |
| Current Assets | $288M | $262M | $213M | $210M | $241M | $297M | $90M | |
| PP&E (Net) | $2M | $3M | $3M | $3M | $2M | $2M | $2M | |
| PP&E (Gross) | $10M | $10M | $9M | $9M | $7M | $6M | $6M | |
| Accum. Depreciation | $8M | $7M | $6M | $6M | $5M | $4M | $4M | |
| Other Non-current Assets | $7M | $9M | $10M | $12M | $12M | $319.0K | $2M | |
| Total Assets | $409M | $274M | $252M | $247M | $299M | $299M | $94M | |
| Accounts Payable | $4M | $2M | $944.0K | $1M | $2M | $757.0K | $152.0K | |
| Accrued Liabilities | $17M | $23M | $20M | $14M | $13M | $8M | $5M | |
| Current Liabilities | $20M | $25M | $20M | $15M | $15M | $9M | $5M | |
| Capital Leases | $4M | $6M | $7M | $9M | $10M | · | · | |
| Other Non-current Liabilities | $4M | $6M | $7M | $9M | $11M | $219.0K | · | |
| Total Liabilities | $25M | $31M | $28M | $25M | $26M | $9M | $6M | |
| Long-term Debt | · | · | · | · | $10M | · | · | |
| Common Stock | $11.0K | $7.0K | $6.0K | $5.0K | $4.0K | $4.0K | · | |
| Retained Earnings | $-692M | $-563M | $-435M | $-334M | $-245M | $-166M | $-93M | |
| AOCI | $786.0K | $379.0K | $258.0K | $-1M | $-103.0K | $-31.0K | · | |
| Stockholders' Equity | $384M | $243M | $224M | $222M | $273M | $290M | $-90M | |
| Liabilities + Equity | $409M | $274M | $252M | $247M | $299M | $299M | $94M | |
| Shares Outstanding | 98,528,949 | 71,021,855 | 54,865,553 | 45,089,537 | 39,430,120 | 36,672,415 | 1,984,222 |
Cash Flow 9
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $25M | $20M | $15M | $14M | $13M | $5M | $1M | |
| Operating Cash Flow | $-111M | $-113M | $-86M | $-75M | $-60M | $-45M | $-24M | |
| CapEx | $712.0K | $1M | $849.0K | $2M | $939.0K | $667.0K | $768.0K | |
| Investing Cash Flow | $-148M | $22M | $-43M | $-109M | $158M | $-216M | $-768.0K | |
| Stock Issued | $244M | $125M | $85M | $25M | $50M | $271M | · | |
| Net Stock Activity | $244M | $125M | $85M | $25M | $50M | $133M | · | |
| Financing Cash Flow | $245M | $127M | $86M | $25M | $49M | $251M | $71M | |
| Net Change in Cash | $-14M | $36M | $-43M | $-159M | $148M | $-11M | $47M | |
| Free Cash Flow | $-112M | $-114M | $-87M | $-77M | $-60M | $-46M | · |
Profitability 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -37.9% | -48.6% | -40.3% | -32.7% | -26.3% | -37.5% | · | |
| ROE | -36.5% | -49.5% | -42.7% | -40.8% | -27.9% | -31.1% | · |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.1 | 10.6 | 10.4 | 13.7 | 15.9 | 33.0 | · | |
| Quick Ratio | 2.2 | 2.4 | 1.1 | 4.3 | 14.9 | 32.6 | · |
Valuation (TTM) 8
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-129M | $-128M | $-101M | $-89M | $-79M | $-74M | · | |
| Market Cap | $806M | $573M | $505M | $266M | $580M | $1.24B | · | |
| P/E | -5.6 | -4.4 | -4.7 | -2.6 | -7.1 | · | · | |
| P/B | 2.1 | 2.4 | 2.3 | 1.2 | 2.1 | 4.3 | · | |
| P / Tangible Book | 2.1 | 2.4 | 2.3 | 1.2 | 2.1 | 4.3 | · | |
| P / Cash Flow | -7.3 | -5.1 | -5.9 | -3.5 | -9.7 | -27.4 | · | |
| P / FCF | -7.2 | -5.0 | -5.8 | -3.4 | -9.6 | -27.0 | · | |
| Earnings Yield | -18.0% | -22.7% | -21.3% | -38.2% | -14.1% | · | · |
Income Statement 10
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SG&A Expense | $9M | $8M | $9M | $8M | $9M | $8M | $8M | $7M | $7M | $7M | $7M | $6M | $6M | $6M | $6M | $6M | |
| Operating Expenses | $45M | $40M | $35M | $37M | $39M | $33M | $40M | $38M | $36M | $29M | $31M | $29M | $25M | $26M | $22M | $26M | |
| Operating Income | $-45M | $-40M | $-35M | $-37M | $-39M | $-33M | $-40M | $-38M | $-36M | $-29M | $-31M | $-29M | $-25M | $-26M | $-22M | $-26M | |
| Other Non-op | $4M | $4M | $4M | $4M | $3M | $3M | $3M | $4M | $4M | $4M | $3M | $3M | $2M | $2M | $1M | $865.0K | |
| Net Income | $-41M | $-36M | $-31M | $-33M | $-36M | $-30M | $-36M | $-35M | $-32M | $-25M | $-28M | $-25M | $-23M | $-24M | $-21M | $-25M | |
| EPS (Basic) | $-0.38 | $-0.34 | $-0.25 | $-0.33 | $-0.47 | $-0.42 | $-0.52 | $-0.49 | $-0.45 | $-0.37 | $-0.49 | $-0.44 | $-0.50 | $-0.53 | $-0.52 | $-0.63 | |
| EPS (Diluted) | $-0.38 | $-0.34 | $-0.25 | $-0.33 | $-0.47 | $-0.42 | $-0.52 | $-0.49 | $-0.45 | $-0.37 | $-0.49 | $-0.44 | $-0.50 | $-0.53 | $-0.52 | $-0.63 | |
| Shares (Basic) | 108,012,388 | 105,472,766 | -160,326,367 | 98,953,331 | 78,126,257 | 71,040,580 | -138,512,709 | 70,542,684 | 70,348,414 | 67,349,551 | -96,695,752 | 57,402,226 | 45,654,208 | 45,090,166 | -78,833,750 | 39,575,660 | |
| Shares (Diluted) | 108,012,388 | 105,472,766 | -160,326,367 | 98,953,331 | 78,126,257 | 71,040,580 | -138,512,709 | 70,542,684 | 70,348,414 | 67,349,551 | -96,695,752 | 57,402,226 | 45,654,208 | 45,090,166 | -78,833,750 | 39,575,660 | |
| EBITDA | $-45M | $-40M | · | $-37M | $-39M | $-33M | · | $-38M | $-36M | $-29M | · | $-29M | $-25M | $-26M | · | $-26M |
Balance Sheet 20
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $37M | $56M | $46M | $50M | $76M | $49M | $59M | $44M | $50M | $56M | $23M | $26M | $104M | $59M | $67M | $29M | |
| Prepaid Expense | $9M | $8M | $7M | $8M | $9M | $8M | $6M | $7M | $8M | $7M | $4M | $5M | $4M | $4M | $4M | $5M | |
| Current Assets | $274M | $290M | $288M | $296M | $291M | $211M | $262M | $279M | $295M | $324M | $213M | $232M | $268M | $193M | $210M | $199M | |
| PP&E (Net) | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | |
| PP&E (Gross) | $10M | $10M | $10M | $11M | $11M | $11M | $10M | $10M | $10M | $9M | $9M | $10M | $10M | $9M | $9M | $9M | |
| Accum. Depreciation | $8M | $8M | $8M | $8M | $8M | $8M | $7M | $7M | $7M | $7M | $6M | $7M | $6M | $6M | $6M | $6M | |
| Other Non-current Assets | $6M | $7M | $7M | $7M | $8M | $8M | $9M | $10M | $9M | $9M | $10M | $10M | $11M | $11M | $12M | $12M | |
| Total Assets | $405M | $437M | $409M | $431M | $347M | $243M | $274M | $302M | $329M | $351M | $252M | $274M | $292M | $227M | $247M | $238M | |
| Accounts Payable | $4M | $3M | $4M | $3M | $3M | $5M | $2M | $4M | $2M | $3M | $944.0K | $4M | $3M | $2M | $1M | $2M | |
| Accrued Liabilities | $17M | $15M | $17M | $17M | $15M | $12M | $23M | $17M | $17M | $12M | $20M | $15M | $11M | $13M | $14M | $12M | |
| Current Liabilities | $21M | $18M | $20M | $20M | $18M | $18M | $25M | $21M | $20M | $15M | $20M | $19M | $15M | $15M | $15M | $13M | |
| Capital Leases | · | · | $4M | · | · | · | $6M | · | · | · | $7M | · | · | · | $9M | · | |
| Other Non-current Liabilities | $3M | $3M | $4M | $4M | $5M | $6M | $6M | $7M | $7M | $7M | $7M | $8M | $8M | $9M | $9M | $10M | |
| Total Liabilities | $23M | $21M | $25M | $24M | $23M | $23M | $31M | $28M | $27M | $22M | $28M | $27M | $23M | $24M | $25M | $23M | |
| Common Stock | $11.0K | $11.0K | $11.0K | $11.0K | $9.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $6.0K | $6.0K | $6.0K | $5.0K | $5.0K | $4.0K | |
| Retained Earnings | $-770M | $-728M | $-692M | $-662M | $-629M | $-593M | $-563M | $-526M | $-492M | $-460M | $-435M | $-407M | $-381M | $-358M | $-334M | $-313M | |
| AOCI | $-1M | $-290.0K | $786.0K | $615.0K | $187.0K | $209.0K | $379.0K | $722.0K | $-256.0K | $-162.0K | $258.0K | $-369.0K | $-567.0K | $-499.0K | $-1M | $-2M | |
| Stockholders' Equity | $381M | $416M | $384M | $407M | $324M | $220M | $243M | $274M | $302M | $329M | $224M | $247M | $269M | $203M | $222M | $215M | |
| Liabilities + Equity | $405M | $437M | $409M | $431M | $347M | $243M | $274M | $302M | $329M | $351M | $252M | $274M | $292M | $227M | $247M | $238M | |
| Shares Outstanding | 103,636,424 | 103,486,412 | 98,528,949 | 97,278,032 | 86,187,328 | 71,078,511 | 71,021,855 | 70,559,183 | 67,672,303 | 67,420,338 | 54,865,553 | 54,540,715 | 54,532,171 | 45,091,215 | 45,089,537 | 39,576,047 |
Cash Flow 9
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $7M | $7M | $6M | $6M | $7M | $7M | $5M | $5M | $5M | $5M | $4M | $4M | $4M | $4M | $3M | $3M | |
| Operating Cash Flow | $-32M | $-32M | $-22M | $-25M | $-31M | $-33M | $-28M | $-29M | $-26M | $-30M | $-24M | $-20M | $-21M | $-21M | $-15M | $-19M | |
| CapEx | $356.0K | $2.0K | $227.0K | $35.0K | $63.0K | $387.0K | $219.0K | $418.0K | $333.0K | $218.0K | $57.0K | $77.0K | $405.0K | $310.0K | $287.0K | $401.0K | |
| Investing Cash Flow | $12M | $-18M | $17M | $-111M | $-77M | $22M | $43M | $23M | $18M | $-62M | $21M | $-58M | $-19M | $13M | $28M | $-685.0K | |
| Stock Issued | $0 | $61M | $0 | $110M | $134M | $0 | $0 | $0 | $0 | $125M | $0 | $226.0K | $85M | $0 | $25M | $-354.0K | |
| Net Stock Activity | · | $61M | · | · | · | $0 | · | · | · | $125M | · | · | · | · | · | · | |
| Financing Cash Flow | $828.0K | $61M | $2M | $109M | $134M | $11.0K | $575.0K | $126.0K | $816.0K | $125M | $453.0K | $31.0K | $85M | $0 | $25M | $1.0K | |
| Net Change in Cash | $-19M | $11M | $-4M | $-26M | $27M | $-10M | $15M | $-6M | $-7M | $33M | $-3M | $-77M | $45M | $-8M | $38M | $-20M | |
| Free Cash Flow | · | $-32M | · | · | · | $-33M | · | · | · | $-30M | · | · | · | $-21M | · | · |
Profitability 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -11.0% | -10.5% | · | -8.9% | -10.8% | -10.1% | · | -12.0% | -10.3% | -8.7% | · | -10.0% | -8.3% | -9.6% | · | -9.0% | |
| ROE | -11.8% | -11.3% | · | -9.6% | -11.6% | -10.9% | · | -13.3% | -11.2% | -9.4% | · | -11.0% | -9.1% | -10.5% | · | -9.8% |
Liquidity & Solvency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 13.2 | 16.3 | · | 14.6 | 16.1 | 12.0 | · | 13.2 | 15.1 | 21.3 | · | 12.3 | 18.5 | 13.0 | · | 15.0 | |
| Quick Ratio | 1.8 | 3.2 | · | 2.5 | 4.2 | 2.8 | · | 2.1 | 2.6 | 3.7 | · | 1.4 | 7.1 | 4.0 | · | 2.2 |
Valuation (TTM) 8
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-146M | $-135M | · | $-134M | $-133M | $-122M | · | $-117M | $-105M | $-97M | · | $-97M | $-92M | $-92M | · | $-87M | |
| Market Cap | $1.12B | $1.31B | · | $1.17B | $875M | $397M | · | $723M | $478M | $927M | · | $330M | $423M | $257M | · | $127M | |
| P/E | -7.1 | -8.1 | · | -7.0 | -5.5 | -3.2 | · | -5.9 | -4.0 | -7.5 | · | -2.9 | -3.6 | -2.5 | · | -1.5 | |
| P/B | 2.9 | 3.2 | · | 2.9 | 2.7 | 1.8 | · | 2.6 | 1.6 | 2.8 | · | 1.3 | 1.6 | 1.3 | · | 0.6 | |
| P / Tangible Book | 2.9 | 3.2 | · | 2.9 | 2.7 | 1.8 | · | 2.6 | 1.6 | 2.8 | · | 1.3 | 1.6 | 1.3 | · | 0.6 | |
| P / Cash Flow | · | -40.4 | · | · | · | -12.2 | · | · | · | -30.7 | · | · | · | -12.5 | · | · | |
| P / FCF | · | -40.4 | · | · | · | -12.0 | · | · | · | -30.5 | · | · | · | -12.3 | · | · | |
| Earnings Yield | -14.0% | -12.3% | · | -14.2% | -18.0% | -31.0% | · | -17.1% | -24.9% | -13.4% | · | -34.7% | -28.0% | -39.6% | · | -68.8% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Net Income | $-129M | $-128M | $-101M | $-89M | $-79M |
| Diluted EPS | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Current Ratio | 14.1 | 10.6 | 10.4 | 13.7 | 15.9 |
| Quick Ratio | 2.2 | 2.4 | 1.1 | 4.3 | 14.9 |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Free Cash Flow | $-112M | $-114M | $-87M | $-77M | $-60M |
My Metrics Your personal watchlist — selected rows from Full Fundamentals
📊
Pick the metrics that matter to you — click the ➕ next to any row in Full Fundamentals above.
Your selection is saved and follows you across all tickers.
Institutional owners (13F) 192 filers · $1.1B total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 40 (+4 vs prior Q) | 28 (+10 vs prior Q) | 68 (+17 vs prior Q) | 44 (-18 vs prior Q) | +10.7M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Nextech Invest Ltd. | $77,571,359 | 7,162,637 | 6.91% | Shares |
| EcoR1 Capital, LLC | $72,865,496 | 6,728,116 | 6.49% | Shares |
| VIKING GLOBAL INVESTORS LP | $55,522,832 | 5,126,762 | 4.95% | Shares |
| STATE STREET CORP | $53,002,020 | 4,894,000 | 4.72% | Shares |
| SR One Capital Management, LP | $49,984,609 | 4,615,384 | 4.45% | Shares |
| Venrock Adviser, LLC | $46,783,055 | 4,319,765 | 4.17% | Shares |
| NEA Management Company, LLC | $44,604,665 | 4,118,621 | 3.97% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $42,791,160 | 3,951,169 | 3.81% | Shares |
| Nextech Invest Ltd. | $42,655,712 | 5,285,714 | 3.80% | Shares |
| AIHC Capital Management Ltd | $41,462,222 | 3,828,460 | 3.69% | Shares |
| Column Group LLC | $38,346,615 | 3,540,777 | 3.42% | Shares |
| ALKEON CAPITAL MANAGEMENT LLC | $33,845,158 | 3,125,130 | 3.01% | Shares |
| VANGUARD GROUP INC | $32,441,356 | 3,965,936 | 2.89% | Shares |
| CITADEL ADVISORS LLC | $23,789,416 | 2,196,622 | 2.12% | Shares |
| First Turn Management, LLC | $21,847,186 | 2,017,284 | 1.95% | Shares |
| ORBIMED ADVISORS LLC | $21,822,450 | 2,015,000 | 1.94% | Shares |
| Integral Health Asset Management, LLC | $20,577,000 | 1,900,000 | 1.83% | Shares |
| MPM BIOIMPACT LLC | $20,383,814 | 1,882,162 | 1.82% | Shares |
| Vivo Capital, LLC | $20,022,352 | 1,848,786 | 1.78% | Shares |
| GOLDMAN SACHS GROUP INC | $19,593,582 | 1,809,195 | 1.75% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $19,414,443 | 1,792,258 | 1.73% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $18,476,857 | 1,706,081 | 1.65% | Shares |
| FMR LLC | $14,205,494 | 1,311,680 | 1.27% | Shares |
| Woodline Partners LP | $13,510,587 | 1,247,515 | 1.20% | Shares |
| ALGERT GLOBAL LLC | $13,161,623 | 1,215,293 | 1.17% | Shares |
| BRAIDWELL LP | $13,153,468 | 1,214,540 | 1.17% | Shares |
| Candriam S.C.A. | $12,764,594 | 1,179,768 | 1.14% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $11,392,109 | 1,051,903 | 1.01% | Shares |
| Defilade Capital Management, L.P. | $11,346,483 | 1,047,690 | 1.01% | Shares |
| Siren, L.L.C. | $10,912,037 | 1,007,575 | 0.97% | Shares |
| Euclidean Capital LLC | $10,715,310 | 989,410 | 0.95% | Shares |
| ROYCE & ASSOCIATES LP | $10,609,761 | 979,664 | 0.94% | Shares |
| EVENTIDE ASSET MANAGEMENT, LLC | $10,337,886 | 954,768 | 0.92% | Shares |
| Qube Research & Technologies Ltd | $8,604,890 | 794,542 | 0.77% | Shares |
| SPHERA FUNDS MANAGEMENT LTD. | $8,154,806 | 752,983 | 0.73% | Shares |
| Jones Hill Capital LP | $8,093,400 | 747,313 | 0.72% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $8,001,995 | 738,873 | 0.71% | Shares |
| NEXTBio Capital Management LP | $7,647,323 | 706,124 | 0.68% | Shares |
| MILLENNIUM MANAGEMENT LLC | $7,556,026 | 697,694 | 0.67% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7,340,823 | 677,823 | 0.65% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $6,808,626 | 628,682 | 0.61% | Shares |
| TWO SIGMA INVESTMENTS, LP | $6,537,681 | 603,664 | 0.58% | Shares |
| ArrowMark Colorado Holdings LLC | $6,312,536 | 582,875 | 0.56% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $6,130,192 | 566,038 | 0.55% | Shares |
| Connor, Clark & Lunn Investment Management Ltd. | $5,614,922 | 518,460 | 0.50% | Shares |
| SUPERSTRING CAPITAL MANAGEMENT LP | $4,397,814 | 406,077 | 0.39% | Shares |
| Blue Owl Capital Holdings LP | $4,332,000 | 400,000 | 0.39% | Shares |
| VICTORY CAPITAL MANAGEMENT INC | $4,256,948 | 393,070 | 0.38% | Shares |
| Redmile Group, LLC | $3,920,568 | 362,010 | 0.35% | Shares |
| Boxer Capital Management, LLC | $3,790,500 | 350,000 | 0.34% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $3,736,762 | 345,038 | 0.33% | Shares |
| Squarepoint Ops LLC | $3,729,235 | 344,343 | 0.33% | Shares |
| Pfizer Inc | $3,553,775 | 372,904 | 0.32% | Shares |
| TD Asset Management Inc | $2,664,202 | 246,002 | 0.24% | Shares |
| CITIGROUP INC | $2,647,339 | 244,445 | 0.24% | Shares |
| BANK OF AMERICA CORP /DE/ | $2,638,892 | 243,665 | 0.24% | Shares |
| Trexquant Investment LP | $2,402,300 | 221,819 | 0.21% | Shares |
| XTX Topco Ltd | $2,359,066 | 217,827 | 0.21% | Shares |
| UBS Group AG | $2,266,578 | 209,287 | 0.20% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1,935,321 | 178,700 | 0.17% | Call option |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1,886,824 | 174,222 | 0.17% | Shares |
| AMERICAN CENTURY COMPANIES INC | $1,826,241 | 168,628 | 0.16% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1,508,251 | 139,266 | 0.13% | Shares |
| Jump Financial, LLC | $1,423,062 | 131,400 | 0.13% | Shares |
| Atom Investors LP | $1,408,756 | 130,079 | 0.13% | Shares |
| Ishara Investments LP | $1,332,090 | 123,000 | 0.12% | Shares |
| Caption Management, LLC | $1,191,300 | 110,000 | 0.11% | Call option |
| SPHERA FUNDS MANAGEMENT LTD. | $1,083,000 | 100,000 | 0.10% | Call option |
| Caption Management, LLC | $1,083,000 | 100,000 | 0.10% | Put option |
| RHUMBLINE ADVISERS | $1,017,131 | 93,919 | 0.09% | Shares |
| Rafferty Asset Management, LLC | $982,963 | 90,763 | 0.09% | Shares |
| Abu Dhabi Investment Council Co P.J.S.C | $968,646 | 89,441 | 0.09% | Shares |
| Bank of New York Mellon Corp | $965,776 | 89,176 | 0.09% | Shares |
| Swiss National Bank | $933,546 | 86,200 | 0.08% | Shares |
| WINTON GROUP Ltd | $898,890 | 83,000 | 0.08% | Shares |
| BlackRock, Inc. | $864,407 | 79,816 | 0.08% | Shares |
| ALLIANCEBERNSTEIN L.P. | $808,473 | 63,810 | 0.07% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $745,169 | 68,806 | 0.07% | Shares |
| WELLS FARGO & COMPANY/MN | $696,228 | 64,287 | 0.06% | Shares |
| Engineers Gate Manager LP | $693,683 | 64,052 | 0.06% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $612,835 | 48,369 | 0.05% | Shares |
| Caption Management, LLC | $521,248 | 48,130 | 0.05% | Shares |
| PROFUND ADVISORS LLC | $494,931 | 45,700 | 0.04% | Shares |
| MetLife Investment Management, LLC | $474,787 | 43,840 | 0.04% | Shares |
| TUDOR INVESTMENT CORP ET AL | $459,289 | 42,409 | 0.04% | Shares |
| Virtus Investment Advisers, LLC | $428,489 | 39,565 | 0.04% | Shares |
| Optimize Financial Inc | $409,596 | 32,328 | 0.04% | Shares |
| AXQ CAPITAL, LP | $395,501 | 36,519 | 0.04% | Shares |
| Quadrature Capital Ltd | $393,086 | 36,296 | 0.04% | Shares |
| LMR Partners LLP | $381,942 | 35,267 | 0.03% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $372,639 | 34,408 | 0.03% | Shares |
| AlphaQuest LLC | $363,086 | 44,387 | 0.03% | Shares |
| Russell Investments Group, Ltd. | $332,914 | 30,740 | 0.03% | Shares |
| Brevan Howard Capital Management LP | $331,983 | 30,654 | 0.03% | Shares |
| Invesco Ltd. | $318,456 | 29,405 | 0.03% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $310,626 | 28,682 | 0.03% | Shares |
| Vanguard Global Advisers, LLC | $306,457 | 28,297 | 0.03% | Shares |
| D. E. Shaw & Co., Inc. | $287,103 | 26,510 | 0.03% | Shares |
| CITADEL ADVISORS LLC | $281,580 | 26,000 | 0.03% | Call option |
| VANGUARD ASSET MANAGEMENT, Ltd | $272,797 | 25,189 | 0.02% | Shares |
Company insiders 11 insiders · 3 officers · 9 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Jacob Chacko | President and CEO | Jan. 2, 2024 A | 808,544 | 0 | 0 | $0 |
| Dominic Piscitelli | Chief Financial Officer | Jan. 2, 2024 A | 83,809 | 0 | 0 | $0 |
| Pratik S Multani | Chief Medical Officer | Jan. 2, 2024 A | 23,809 | 0 | 0 | $0 |
| Richard A. Heyman | Director | July 24, 2026 M | 206,672 | 0 | 3 | $-161,062 |
| Angie You | Director | June 14, 2023 A | — | 0 | 0 | $0 |
| Mardi Dier | Director | June 14, 2023 A | — | 0 | 0 | $0 |
| Lori Anne Kunkel | Director | June 14, 2023 A | — | 0 | 0 | $0 |
| Steven L. Hoerter | Director | June 14, 2023 A | — | 0 | 0 | $0 |
| Peter Svennilson | Director | June 16, 2021 A | 4,768,181 | 0 | 0 | $0 |
| GORDON CARL L | Director | June 16, 2021 A | 2,212,571 | 0 | 0 | $0 |
| Richard H Scheller | Director | May 24, 2021 S | 39,092 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 2 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| SR One Capital Management, LLC, SR One Capital Opportunities Fund I, LP, SR One Capital Opportunities Partners I, LP, AMZL, LP, SR One Capital SMA Partners, LP, SR One Capital Fund II Aggregator, LP, SR One Capital Partners II, LP, Simeon George ×2 filings | Aug. 14, 2025 | 4.75% | Amendment | — | SEC |
| OrbiMed Advisors LLC, OrbiMed Capital GP VI LLC, OrbiMed Capital LLC ×5 filings | Dec. 27, 2022 | — | Initial filing | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership Held by 43 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 0.78% | 29,424 NS | April 30, 2026 | N-PORT |
| CANC · Tema ETF Trust | 0.28% | 57,977 NS | May 31, 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0.24% | 124,292 NS | April 30, 2026 | N-PORT |
| IWC · iShares Trust | 0.22% | 253,807 SH | Aug. 8, 2026 | Daily |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0.10% | 5,635 SH | Aug. 8, 2026 | Daily |
| ESSC · Strategy Shares | 0.08% | 2,136 NS | April 30, 2026 | N-PORT |
| IBB · iShares Trust | 0.06% | 453,772 SH | Aug. 8, 2026 | Daily |
| AVSC · AMERICAN CENTURY ETF TRUST | 0.04% | 146,225 NS | May 31, 2026 | N-PORT |
| BIB · ProShares Trust | 0.04% | 3,711 NS | May 31, 2026 | N-PORT |
| IWN · iShares Trust | 0.04% | 478,494 SH | Aug. 8, 2026 | Daily |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0.04% | 44,861 SH | Aug. 8, 2026 | Daily |
| IWM · iShares Trust | 0.03% | 1,907,813 SH | Aug. 8, 2026 | Daily |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.03% | 62,749 SH | Aug. 8, 2026 | Daily |
| DFAS · Dimensional ETF Trust | 0.02% | 327,184 NS | April 30, 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.02% | 429,878 SH | Aug. 8, 2026 | Daily |
| RSSL · Global X Funds | 0.02% | 28,629 NS | April 30, 2026 | N-PORT |
| IWO · iShares Trust | 0.02% | 209,299 SH | Aug. 8, 2026 | Daily |
| ISCV · iShares Trust | 0.02% | 9,176 SH | Aug. 8, 2026 | Daily |
| ITWO · ProShares Trust | 0.01% | 3,114 NS | May 31, 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0.01% | 365,890 NS | May 31, 2026 | N-PORT |
| ISCB · iShares Trust | 0.01% | 2,918 SH | Aug. 8, 2026 | Daily |
| VXF · VANGUARD INDEX FUNDS | 0.01% | 942,459 SH | Aug. 8, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.01% | 23,339 SH | Aug. 8, 2026 | Daily |
| VHT · VANGUARD WORLD FUND | 0.01% | 125,232 SH | Aug. 8, 2026 | Daily |
| ISCG · iShares Trust | 0.01% | 7,494 SH | Aug. 8, 2026 | Daily |
| UWM · ProShares Trust | 0.01% | 2,435 NS | May 31, 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0.01% | 20,039 NS | April 30, 2026 | N-PORT |
| URTY · ProShares Trust | 0.01% | 2,463 NS | May 31, 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0.01% | 2,102 NS | April 30, 2026 | N-PORT |
| WSML · iShares Trust | 0.01% | 2,651 SH | Aug. 8, 2026 | Daily |
| DCOR · Dimensional ETF Trust | 0.00% | 9,920 NS | April 30, 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0.00% | 40,897 NS | May 31, 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0.00% | 2,346 NS | May 31, 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0.00% | 30,514 NS | April 30, 2026 | N-PORT |
| HDG · ProShares Trust | 0.00% | 62 NS | May 31, 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0.00% | 97,392 NS | April 30, 2026 | N-PORT |
| ITOT · iShares Trust | 0.00% | 116,415 SH | Aug. 8, 2026 | Daily |
| IWV · iShares Trust | 0.00% | 17,499 SH | Aug. 8, 2026 | Daily |
| SCHB · SCHWAB STRATEGIC TRUST | 0.00% | 46,809 NS | May 31, 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0.00% | 11,258 NS | April 30, 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0.00% | 7,147 NS | May 31, 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 2,918,973 SH | Aug. 8, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 5,372 SH | Aug. 8, 2026 | Daily |