ORIC Oric Pharmaceuticals, Inc. - Common Stock
NASDAQ · Biotechnology · View on SEC EDGAR ↗ close Oct 2, 2026 10-K/10-Q Aug 3, 2026
$12.21
· of 52w range
· above low
· to high
$7.2352w low
$14.9352w high
Market Cap (MRQ)
$1.26B
P/E
-8.7
EPS
$-1.47
your badges
52W Range
$7–$15
Analyst Rating
BUY
Price Target
$21
P/E
-8.7
ROE
-36.5%
Net Profit Margin
·
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ORIC Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$12.21
Market Cap (MRQ)
$1.26B
P/E
-8.7
EPS
$-1.47
ROE
-36.5%
52W Range
$7–$15
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10-Year Performance Revenue, net income, margins and EPS trends
EPS$-1.472021-12-31 → 2025-12-31
Free Cash Flow$-112M2020-12-31 → 2025-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | ORIC | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E | -8.75Y avg ≈-4.9 | ≈-4.9 | · | · | |
| P/B (MRQ) | 3.35Y avg ≈2.0 | ≈2.0 | 4.2 | Undervalued | |
| Price / FCF (TTM) | -11.35Y avg ≈-6.2 | ≈-6.2 | · | · | |
| Price / Cash Flow (TTM) | -11.35Y avg ≈-6.3 | ≈-6.3 | · | · | |
| Price / Tangible Book | 3.35Y avg ≈2.0 | ≈2.0 | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | ORIC | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| ROA | -37.9%5Y avg ≈-37.2% | ≈-37.2% | -37.9% | In line | |
| ROE | -36.5%5Y avg ≈-39.5% | ≈-39.5% | -59.7% | Top tier |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | ORIC | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio (MRQ) | 13.25Y avg ≈12.9 | ≈12.9 | 11.6 | In line | |
| Quick Ratio | 2.25Y avg ≈5.0 | ≈5.0 | 11.0 | Low liquidity |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
8.2%
Next Report
Nov 11, 2026
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | Aug 10, 2026 | $-0.38 | $-0.37 | -3.1% |
| March 31, 2026 | $-0.34 | $-0.33 | -2.7% | |
| Dec. 31, 2025 | $-0.30 | $-0.37 | 19.2% | |
| Sept. 30, 2025 | $-0.33 | $-0.41 | 20.1% | |
| June 30, 2025 | $-0.47 | $-0.45 | -4.0% | |
| March 31, 2025 | $-0.42 | $-0.52 | 19.4% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| SG&A Expense | $33M | $29M | $26M | $25M | $22M | $13M | $6M | |
| Operating Expenses | $143M | $143M | $111M | $92M | $79M | $74M | $29M | |
| Operating Income | $-143M | $-143M | $-111M | $-92M | $-79M | $-74M | $-29M | |
| Other Non-op | $14M | $15M | $10M | $3M | $156.0K | $483.0K | $2M | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-129M | $-128M | $-101M | $-89M | $-79M | $-74M | $-27M | |
| EPS (Basic) | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 | · | · | |
| EPS (Diluted) | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 | · | · | |
| Shares (Basic) | 87,793,801 | 69,727,940 | 51,450,848 | 39,655,260 | 37,954,280 | · | · | |
| Shares (Diluted) | 87,793,801 | 69,727,940 | 51,450,848 | 39,655,260 | 37,954,280 | · | · | |
| EBITDA | $-143M | $-143M | $-111M | $-92M | $-79M | $-74M | · |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $46M | $59M | $23M | $67M | $226M | $78M | $89M | |
| Short-term Investments | · | · | · | · | · | $215M | · | |
| Prepaid Expense | $7M | $6M | $4M | $4M | $4M | $3M | $840.0K | |
| Current Assets | $288M | $262M | $213M | $210M | $241M | $297M | $90M | |
| PP&E (Net) | $2M | $3M | $3M | $3M | $2M | $2M | $2M | |
| PP&E (Gross) | $10M | $10M | $9M | $9M | $7M | $6M | $6M | |
| Accum. Depreciation | $8M | $7M | $6M | $6M | $5M | $4M | $4M | |
| Other Non-current Assets | $7M | $9M | $10M | $12M | $12M | $319.0K | $2M | |
| Total Assets | $409M | $274M | $252M | $247M | $299M | $299M | $94M | |
| Accounts Payable | $4M | $2M | $944.0K | $1M | $2M | $757.0K | $152.0K | |
| Accrued Liabilities | $17M | $23M | $20M | $14M | $13M | $8M | $5M | |
| Current Liabilities | $20M | $25M | $20M | $15M | $15M | $9M | $5M | |
| Capital Leases | $4M | $6M | $7M | $9M | $10M | · | · | |
| Other Non-current Liabilities | $4M | $6M | $7M | $9M | $11M | $219.0K | · | |
| Total Liabilities | $25M | $31M | $28M | $25M | $26M | $9M | $6M | |
| Long-term Debt | · | · | · | · | $10M | · | · | |
| Common Stock | $11.0K | $7.0K | $6.0K | $5.0K | $4.0K | $4.0K | · | |
| Retained Earnings | $-692M | $-563M | $-435M | $-334M | $-245M | $-166M | $-93M | |
| AOCI | $786.0K | $379.0K | $258.0K | $-1M | $-103.0K | $-31.0K | · | |
| Stockholders' Equity | $384M | $243M | $224M | $222M | $273M | $290M | $-90M | |
| Liabilities + Equity | $409M | $274M | $252M | $247M | $299M | $299M | $94M | |
| Shares Outstanding | 98,528,949 | 71,021,855 | 54,865,553 | 45,089,537 | 39,430,120 | 36,672,415 | 1,984,222 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $25M | $20M | $15M | $14M | $13M | $5M | $1M | |
| Operating Cash Flow | $-111M | $-113M | $-86M | $-75M | $-60M | $-45M | $-24M | |
| CapEx | $712.0K | $1M | $849.0K | $2M | $939.0K | $667.0K | $768.0K | |
| Investing Cash Flow | $-148M | $22M | $-43M | $-109M | $158M | $-216M | $-768.0K | |
| Stock Issued | $244M | $125M | $85M | $25M | $50M | $271M | · | |
| Net Stock Activity | $244M | $125M | $85M | $25M | $50M | $133M | · | |
| Financing Cash Flow | $245M | $127M | $86M | $25M | $49M | $251M | $71M | |
| Net Change in Cash | $-14M | $36M | $-43M | $-159M | $148M | $-11M | $47M | |
| Free Cash Flow | $-112M | $-114M | $-87M | $-77M | $-60M | $-46M | · |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -37.9% | -48.6% | -40.3% | -32.7% | -26.3% | -37.5% | · | |
| ROE | -36.5% | -49.5% | -42.7% | -40.8% | -27.9% | -31.1% | · |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.1 | 10.6 | 10.4 | 13.7 | 15.9 | 33.0 | · | |
| Quick Ratio | 2.2 | 2.4 | 1.1 | 4.3 | 14.9 | 32.6 | · |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $3.90 | $3.42 | $4.08 | $4.93 | $6.92 | $7.90 | · | |
| Cash Flow / Share | $-1.26 | $-1.62 | $-1.67 | $-1.89 | · | · | · | |
| Cash / Share | $0.46 | $0.84 | $0.43 | $1.48 | $5.73 | $2.14 | · | |
| EPS (TTM) | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 | · | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-129M | $-128M | $-101M | $-89M | $-79M | $-74M | · | |
| Market Cap | $806M | $573M | $505M | $266M | $580M | $1.24B | · | |
| P/E | -5.6 | -4.4 | -4.7 | -2.6 | -7.1 | · | · | |
| P/B | 2.1 | 2.4 | 2.3 | 1.2 | 2.1 | 4.3 | · | |
| P / Tangible Book | 2.1 | 2.4 | 2.3 | 1.2 | 2.1 | 4.3 | · | |
| P / Cash Flow | -7.3 | -5.1 | -5.9 | -3.5 | -9.7 | -27.4 | · | |
| P / FCF | -7.2 | -5.0 | -5.8 | -3.4 | -9.6 | -27.0 | · | |
| Earnings Yield | -18.0% | -22.7% | -21.3% | -38.2% | -14.1% | · | · |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SG&A Expense | $9M | $8M | $9M | $8M | $9M | $8M | $8M | $7M | $7M | $7M | $7M | $6M | $6M | $6M | $6M | $6M | |
| Operating Expenses | $45M | $40M | $35M | $37M | $39M | $33M | $40M | $38M | $36M | $29M | $31M | $29M | $25M | $26M | $22M | $26M | |
| Operating Income | $-45M | $-40M | $-35M | $-37M | $-39M | $-33M | $-40M | $-38M | $-36M | $-29M | $-31M | $-29M | $-25M | $-26M | $-22M | $-26M | |
| Other Non-op | $4M | $4M | $4M | $4M | $3M | $3M | $3M | $4M | $4M | $4M | $3M | $3M | $2M | $2M | $1M | $865.0K | |
| Net Income | $-41M | $-36M | $-31M | $-33M | $-36M | $-30M | $-36M | $-35M | $-32M | $-25M | $-28M | $-25M | $-23M | $-24M | $-21M | $-25M | |
| EPS (Basic) | $-0.38 | $-0.34 | $-0.25 | $-0.33 | $-0.47 | $-0.42 | $-0.52 | $-0.49 | $-0.45 | $-0.37 | $-0.49 | $-0.44 | $-0.50 | $-0.53 | $-0.52 | $-0.63 | |
| EPS (Diluted) | $-0.38 | $-0.34 | $-0.25 | $-0.33 | $-0.47 | $-0.42 | $-0.52 | $-0.49 | $-0.45 | $-0.37 | $-0.49 | $-0.44 | $-0.50 | $-0.53 | $-0.52 | $-0.63 | |
| Shares (Basic) | 108,012,388 | 105,472,766 | · | 98,953,331 | 78,126,257 | 71,040,580 | · | 70,542,684 | 70,348,414 | 67,349,551 | · | 57,402,226 | 45,654,208 | 45,090,166 | · | 39,575,660 | |
| Shares (Diluted) | 108,012,388 | 105,472,766 | · | 98,953,331 | 78,126,257 | 71,040,580 | · | 70,542,684 | 70,348,414 | 67,349,551 | · | 57,402,226 | 45,654,208 | 45,090,166 | · | 39,575,660 | |
| EBITDA | $-45M | $-40M | · | $-37M | $-39M | $-33M | · | $-38M | $-36M | $-29M | · | $-29M | $-25M | $-26M | · | $-26M |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $37M | $56M | $46M | $50M | $76M | $49M | $59M | $44M | $50M | $56M | $23M | $26M | $104M | $59M | $67M | $29M | |
| Prepaid Expense | $9M | $8M | $7M | $8M | $9M | $8M | $6M | $7M | $8M | $7M | $4M | $5M | $4M | $4M | $4M | $5M | |
| Current Assets | $274M | $290M | $288M | $296M | $291M | $211M | $262M | $279M | $295M | $324M | $213M | $232M | $268M | $193M | $210M | $199M | |
| PP&E (Net) | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | |
| PP&E (Gross) | $10M | $10M | $10M | $11M | $11M | $11M | $10M | $10M | $10M | $9M | $9M | $10M | $10M | $9M | $9M | $9M | |
| Accum. Depreciation | $8M | $8M | $8M | $8M | $8M | $8M | $7M | $7M | $7M | $7M | $6M | $7M | $6M | $6M | $6M | $6M | |
| Other Non-current Assets | $6M | $7M | $7M | $7M | $8M | $8M | $9M | $10M | $9M | $9M | $10M | $10M | $11M | $11M | $12M | $12M | |
| Total Assets | $405M | $437M | $409M | $431M | $347M | $243M | $274M | $302M | $329M | $351M | $252M | $274M | $292M | $227M | $247M | $238M | |
| Accounts Payable | $4M | $3M | $4M | $3M | $3M | $5M | $2M | $4M | $2M | $3M | $944.0K | $4M | $3M | $2M | $1M | $2M | |
| Accrued Liabilities | $17M | $15M | $17M | $17M | $15M | $12M | $23M | $17M | $17M | $12M | $20M | $15M | $11M | $13M | $14M | $12M | |
| Current Liabilities | $21M | $18M | $20M | $20M | $18M | $18M | $25M | $21M | $20M | $15M | $20M | $19M | $15M | $15M | $15M | $13M | |
| Capital Leases | · | · | $4M | · | · | · | $6M | · | · | · | $7M | · | · | · | $9M | · | |
| Other Non-current Liabilities | $3M | $3M | $4M | $4M | $5M | $6M | $6M | $7M | $7M | $7M | $7M | $8M | $8M | $9M | $9M | $10M | |
| Total Liabilities | $23M | $21M | $25M | $24M | $23M | $23M | $31M | $28M | $27M | $22M | $28M | $27M | $23M | $24M | $25M | $23M | |
| Common Stock | $11.0K | $11.0K | $11.0K | $11.0K | $9.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $6.0K | $6.0K | $6.0K | $5.0K | $5.0K | $4.0K | |
| Retained Earnings | $-770M | $-728M | $-692M | $-662M | $-629M | $-593M | $-563M | $-526M | $-492M | $-460M | $-435M | $-407M | $-381M | $-358M | $-334M | $-313M | |
| AOCI | $-1M | $-290.0K | $786.0K | $615.0K | $187.0K | $209.0K | $379.0K | $722.0K | $-256.0K | $-162.0K | $258.0K | $-369.0K | $-567.0K | $-499.0K | $-1M | $-2M | |
| Stockholders' Equity | $381M | $416M | $384M | $407M | $324M | $220M | $243M | $274M | $302M | $329M | $224M | $247M | $269M | $203M | $222M | $215M | |
| Liabilities + Equity | $405M | $437M | $409M | $431M | $347M | $243M | $274M | $302M | $329M | $351M | $252M | $274M | $292M | $227M | $247M | $238M | |
| Shares Outstanding | 103,636,424 | 103,486,412 | 98,528,949 | 97,278,032 | 86,187,328 | 71,078,511 | 71,021,855 | 70,559,183 | 67,672,303 | 67,420,338 | 54,865,553 | 54,540,715 | 54,532,171 | 45,091,215 | 45,089,537 | 39,576,047 |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $7M | $7M | $6M | $6M | $7M | $7M | $5M | $5M | $5M | $5M | $4M | $4M | $4M | $4M | $3M | $3M | |
| Operating Cash Flow | $-32M | $-32M | $-22M | $-25M | $-31M | $-33M | $-28M | $-29M | $-26M | $-30M | $-24M | $-20M | $-21M | $-21M | $-15M | $-19M | |
| CapEx | $356.0K | $2.0K | $227.0K | $35.0K | $63.0K | $387.0K | $219.0K | $418.0K | $333.0K | $218.0K | $57.0K | $77.0K | $405.0K | $310.0K | $287.0K | $401.0K | |
| Investing Cash Flow | $12M | $-18M | $17M | $-111M | $-77M | $22M | $43M | $23M | $18M | $-62M | $21M | $-58M | $-19M | $13M | $28M | $-685.0K | |
| Stock Issued | $0 | $61M | $0 | $110M | $134M | $0 | $0 | $0 | $0 | $125M | $0 | $226.0K | $85M | $0 | $25M | $-354.0K | |
| Net Stock Activity | · | $61M | · | · | · | $0 | · | · | · | $125M | · | · | · | · | · | · | |
| Financing Cash Flow | $828.0K | $61M | $2M | $109M | $134M | $11.0K | $575.0K | $126.0K | $816.0K | $125M | $453.0K | $31.0K | $85M | $0 | $25M | $1.0K | |
| Net Change in Cash | $-19M | $11M | $-4M | $-26M | $27M | $-10M | $15M | $-6M | $-7M | $33M | $-3M | $-77M | $45M | $-8M | $38M | $-20M | |
| Free Cash Flow | · | $-32M | · | · | · | $-33M | · | · | · | $-30M | · | · | · | $-21M | · | · |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -11.0% | -10.5% | · | -8.9% | -10.8% | -10.1% | · | -12.0% | -10.3% | -8.7% | · | -10.0% | -8.3% | -9.6% | · | -9.0% | |
| ROE | -11.8% | -11.3% | · | -9.6% | -11.6% | -10.9% | · | -13.3% | -11.2% | -9.4% | · | -11.0% | -9.1% | -10.5% | · | -9.8% |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 13.2 | 16.3 | · | 14.6 | 16.1 | 12.0 | · | 13.2 | 15.1 | 21.3 | · | 12.3 | 18.5 | 13.0 | · | 15.0 | |
| Quick Ratio | 1.8 | 3.2 | · | 2.5 | 4.2 | 2.8 | · | 2.1 | 2.6 | 3.7 | · | 1.4 | 7.1 | 4.0 | · | 2.2 |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $3.68 | $4.02 | · | $4.18 | $3.76 | $3.09 | · | $3.88 | $4.47 | $4.87 | · | $4.54 | $4.93 | $4.50 | · | $5.43 | |
| Cash Flow / Share | · | $-0.31 | · | · | · | $-0.46 | · | · | · | $-0.45 | · | · | · | $-0.46 | · | · | |
| Cash / Share | $0.36 | $0.55 | · | $0.51 | $0.88 | $0.69 | · | $0.63 | $0.74 | $0.84 | · | $0.48 | $1.90 | $1.31 | · | $0.73 | |
| EPS (TTM) | $-1.30 | $-1.39 | · | $-1.74 | $-1.90 | $-1.88 | · | $-1.80 | $-1.75 | $-1.80 | · | $-1.99 | $-2.18 | $-2.19 | · | $-2.31 |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-140M | $-135M | · | $-135M | $-137M | $-133M | · | $-120M | $-111M | $-102M | · | $-93M | $-93M | $-90M | · | $-91M | |
| Market Cap | $1.12B | $1.31B | · | $1.17B | $875M | $397M | · | $723M | $478M | $927M | · | $330M | $423M | $257M | · | $127M | |
| P/E | -8.3 | -9.1 | · | -6.9 | -5.3 | -3.0 | · | -5.7 | -4.0 | -7.6 | · | -3.0 | -3.6 | -2.6 | · | -1.4 | |
| P/B | 2.9 | 3.2 | · | 2.9 | 2.7 | 1.8 | · | 2.6 | 1.6 | 2.8 | · | 1.3 | 1.6 | 1.3 | · | 0.6 | |
| P / Tangible Book | 2.9 | 3.2 | · | 2.9 | 2.7 | 1.8 | · | 2.6 | 1.6 | 2.8 | · | 1.3 | 1.6 | 1.3 | · | 0.6 | |
| P / Cash Flow | · | -40.4 | · | · | · | -12.2 | · | · | · | -30.7 | · | · | · | -12.5 | · | · | |
| Earnings Yield | -12.0% | -11.0% | · | -14.5% | -18.7% | -33.7% | · | -17.6% | -24.8% | -13.1% | · | -32.9% | -28.1% | -38.4% | · | -72.2% |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Net Income | $-129M | $-128M | $-101M | $-89M | $-79M |
| Diluted EPS | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Current Ratio | 14.1 | 10.6 | 10.4 | 13.7 | 15.9 |
| Quick Ratio | 2.2 | 2.4 | 1.1 | 4.3 | 14.9 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Free Cash Flow | $-112M | $-114M | $-87M | $-77M | $-60M |
Institutional owners (13F) 188 filers · $1.3B total · As of Sept. 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
188
Value held
$1.3B
New positions
32
Exited positions
29
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 32 (-11 vs prior Q) | 29 (+11 vs prior Q) | 81 (+27 vs prior Q) | 41 (-22 vs prior Q) | +4.7M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Nextech Invest Ltd. | $77,571,359 | 7,162,637 | 5.94% | Shares |
| BlackRock, Inc. | $73,903,628 | 6,823,973 | 5.66% | Shares |
| EcoR1 Capital, LLC | $72,865,496 | 6,728,116 | 5.58% | Shares |
| VIKING GLOBAL INVESTORS LP | $55,522,832 | 5,126,762 | 4.25% | Shares |
| STATE STREET CORP | $53,002,020 | 4,894,000 | 4.06% | Shares |
| SR One Capital Management, LP | $49,984,609 | 4,615,384 | 3.83% | Shares |
| Venrock Adviser, LLC | $46,783,055 | 4,319,765 | 3.58% | Shares |
| NEA Management Company, LLC | $44,604,665 | 4,118,621 | 3.42% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $42,791,160 | 3,951,169 | 3.28% | Shares |
| AIHC Capital Management Ltd | $41,462,222 | 3,828,460 | 3.18% | Shares |
| ALKEON CAPITAL MANAGEMENT LLC | $40,494,410 | 3,739,096 | 3.10% | Shares |
| Column Group LLC | $38,346,615 | 3,540,777 | 2.94% | Shares |
| VANGUARD GROUP INC | $37,153,347 | 4,541,974 | 2.85% | Shares |
| Siren, L.L.C. | $32,470,419 | 2,998,192 | 2.49% | Shares |
| FMR LLC | $28,542,194 | 2,635,475 | 2.19% | Shares |
| CITADEL ADVISORS LLC | $28,107,088 | 2,595,299 | 2.15% | Shares |
| GOLDMAN SACHS GROUP INC | $26,552,951 | 2,451,796 | 2.03% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $22,639,952 | 2,090,089 | 1.73% | Shares |
| First Turn Management, LLC | $21,847,186 | 2,017,284 | 1.67% | Shares |
| ORBIMED ADVISORS LLC | $21,822,450 | 2,015,000 | 1.67% | Shares |
| Integral Health Asset Management, LLC | $20,577,000 | 1,900,000 | 1.58% | Shares |
| MPM BIOIMPACT LLC | $20,383,814 | 1,882,162 | 1.56% | Shares |
| Vivo Capital, LLC | $20,022,352 | 1,848,786 | 1.53% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $19,503,242 | 1,801,399 | 1.49% | Shares |
| FRANKLIN RESOURCES INC | $19,465,593 | 1,797,377 | 1.49% | Shares |
| MORGAN STANLEY | $19,429,237 | 1,794,020 | 1.49% | Shares |
| D. E. Shaw & Co., Inc. | $17,113,739 | 1,580,216 | 1.31% | Shares |
| Woodline Partners LP | $13,510,587 | 1,247,515 | 1.03% | Shares |
| ALGERT GLOBAL LLC | $13,161,623 | 1,215,293 | 1.01% | Shares |
| BRAIDWELL LP | $13,153,468 | 1,214,540 | 1.01% | Shares |
| Candriam S.C.A. | $12,764,594 | 1,179,768 | 0.98% | Shares |
| BANK OF AMERICA CORP /DE/ | $11,675,336 | 1,078,055 | 0.89% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $11,392,109 | 1,051,903 | 0.87% | Shares |
| Defilade Capital Management, L.P. | $11,346,483 | 1,047,690 | 0.87% | Shares |
| Euclidean Capital LLC | $10,715,310 | 989,410 | 0.82% | Shares |
| ROYCE & ASSOCIATES LP | $10,609,761 | 979,664 | 0.81% | Shares |
| EVENTIDE ASSET MANAGEMENT, LLC | $10,337,886 | 954,768 | 0.79% | Shares |
| NORTHERN TRUST CORP | $8,732,272 | 806,304 | 0.67% | Shares |
| Qube Research & Technologies Ltd | $8,604,890 | 794,542 | 0.66% | Shares |
| SPHERA FUNDS MANAGEMENT LTD. | $8,154,806 | 752,983 | 0.62% | Shares |
| Jones Hill Capital LP | $8,093,400 | 747,313 | 0.62% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $8,001,995 | 738,873 | 0.61% | Shares |
| NEXTBio Capital Management LP | $7,647,323 | 706,124 | 0.59% | Shares |
| MILLENNIUM MANAGEMENT LLC | $7,556,026 | 697,694 | 0.58% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7,340,823 | 677,823 | 0.56% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $6,808,626 | 628,682 | 0.52% | Shares |
| TWO SIGMA INVESTMENTS, LP | $6,537,681 | 603,664 | 0.50% | Shares |
| ArrowMark Colorado Holdings LLC | $6,312,536 | 582,875 | 0.48% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $6,130,192 | 566,038 | 0.47% | Shares |
| Connor, Clark & Lunn Investment Management Ltd. | $5,614,922 | 518,460 | 0.43% | Shares |
Activists & 5%+ owners 2 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| SR One Capital Management, LLC, SR One Capital Opportunities Fund I, LP, SR One Capital Opportunities Partners I, LP, AMZL, LP, SR One Capital SMA Partners, LP, SR One Capital Fund II Aggregator, LP, SR One Capital Partners II, LP, Simeon George ×2 filings | Aug. 14, 2025 | 4.75% | Amendment | · | SEC |
| OrbiMed Advisors LLC, OrbiMed Capital GP VI LLC, OrbiMed Capital LLC ×5 filings | Dec. 27, 2022 | · | Initial filing | · | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 11 insiders · 3 officers · 9 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Jacob Chacko | PRESIDENT AND CEO | Jan. 2, 2026 A | 581,711 | 0 | 2 | $-763,888 |
| Dominic Piscitelli | Chief Financial Officer | Sept. 28, 2026 M | 69,828 | 0 | 7 | $-2,202,895 |
| Pratik S Multani | Chief Medical Officer | Jan. 2, 2026 A | 68,149 | 0 | 1 | $-97,123 |
| Richard A. Heyman | Director | Oct. 1, 2026 M | 203,472 | 0 | 7 | $-327,959 |
| Angie You | Director | Jan. 2, 2026 A | 28,000 | 0 | 0 | $0 |
| Mardi Dier | Director | Jan. 2, 2026 A | · | 0 | 0 | $0 |
| Lori Anne Kunkel | Director | Jan. 2, 2026 A | 84,200 | 0 | 0 | $0 |
| Steven L. Hoerter | Director | Jan. 2, 2026 A | · | 0 | 0 | $0 |
| Peter Svennilson | Director | June 16, 2021 A | 4,768,181 | 0 | 0 | $0 |
| GORDON CARL L | Director | June 16, 2021 A | 2,212,571 | 0 | 0 | $0 |
| Richard H Scheller | Director | May 24, 2021 S | 39,092 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 33 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 0.90% | 37,585 NS | July 31, 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0.25% | 110,953 NS | July 31, 2026 | N-PORT |
| IWC · iShares Trust | 0.21% | 254,020 SH | Sept. 11, 2026 | Daily |
| ESSC · Strategy Shares | 0.13% | 4,173 NS | July 31, 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0.09% | 7,315 SH | Oct. 2, 2026 | Daily |
| PWS · Pacer Funds Trust | 0.07% | 1,516 NS | July 31, 2026 | N-PORT |
| IBB · iShares Trust | 0.05% | 468,238 SH | Sept. 11, 2026 | Daily |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0.04% | 44,861 SH | Aug. 19, 2026 | Daily |
| IWM · iShares Trust | 0.03% | 1,911,685 SH | Sept. 11, 2026 | Daily |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.03% | 61,621 SH | Oct. 2, 2026 | Daily |
| RSSL · Global X Funds | 0.03% | 35,677 NS | July 31, 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0.02% | 334,199 NS | July 31, 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.02% | 429,878 SH | Aug. 19, 2026 | Daily |
| IWO · iShares Trust | 0.02% | 214,505 SH | Sept. 11, 2026 | Daily |
| VXF · VANGUARD INDEX FUNDS | 0.01% | 942,459 SH | Aug. 19, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.01% | 23,339 SH | Aug. 19, 2026 | Daily |
| VHT · VANGUARD WORLD FUND | 0.01% | 125,232 SH | Aug. 19, 2026 | Daily |
| ISCG · iShares Trust | 0.01% | 7,518 SH | Sept. 11, 2026 | Daily |
| FHLC · FIDELITY COVINGTON TRUST | 0.01% | 20,639 NS | July 31, 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0.01% | 3,366 NS | July 31, 2026 | N-PORT |
| WSML · iShares Trust | 0.00% | 2,678 SH | Sept. 11, 2026 | Daily |
| DFAC · Dimensional ETF Trust | 0.00% | 198,641 NS | July 31, 2026 | N-PORT |
| TILT · FlexShares Trust | 0.00% | 7,742 NS | July 31, 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0.00% | 9,920 NS | July 31, 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0.00% | 22,716 NS | July 31, 2026 | N-PORT |
| ITOT · iShares Trust | 0.00% | 116,405 SH | Sept. 11, 2026 | Daily |
| IWV · iShares Trust | 0.00% | 17,689 SH | Sept. 3, 2026 | Daily |
| DFUS · Dimensional ETF Trust | 0.00% | 11,672 NS | July 31, 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 2,918,973 SH | Aug. 19, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 5,372 SH | Aug. 19, 2026 | Daily |
| IWN · iShares Trust | · | 480,334 SH | Sept. 11, 2026 | Daily |
| ISCB · iShares Trust | · | 2,918 SH | Sept. 11, 2026 | Daily |
| ISCV · iShares Trust | · | 9,176 SH | Sept. 11, 2026 | Daily |
ORIC Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 20 analysts
BUY
Median target
$22.00
+80.3%
8 40.0%
Strong Buy
10 50.0%
Buy
2 10.0%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
13 analysts · 2026-09-30Mean target $21.08 +72.7%
← Below all targets
Current price $12.21
Low$14.00
Mean$21.08
High$27.00
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| ORIC | $806M | -5.6 | · | · | -36.5% | · |
| INBX | $1.15B | -8.7 | 550.0% | -10773.5% | -365.9% | · |
| TYRA | $1.41B | -13.1 | · | · | -42.7% | · |
| AVBP | $854M | -4.7 | · | · | -59.7% | · |
| KLRA | · | · | · | · | · | · |
| DMRA | · | · | 38.3% | -17981.1% | -167.0% | · |
| REPL | $633M | -2.3 | · | · | -146.2% | · |
| MNKD | $1.75B | 283.5 | 22.2% | 1.7% | -11.1% | · |
| TRAX | · | · | · | · | · | · |
| BCAX | $953M | -6.7 | · | · | -33.0% | · |
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Source: SEC 10-Q filed Aug 3, 2026