TLPH Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $1.13
Market Cap (MRQ) $59M
EPS $-1.29
Revenue $28.0K
ROE -120.8%
52W Range $1–$2

TLPH Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
range
bars

Bar granularity adapts to the selected period — hover the chart to see open/high/low/close for a bar.

Stock splits 1
Ex-date Split Type
Oct. 26, 2022 1-for-20 Reverse

About Talphera, Inc. - Common Stock Company overview from Wikipedia

05 · wikidata
sectorHealthcare industryPharmaceuticals employees12 countryUS

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$28.0K
2016-12-31 → 2025-12-31
EPS$-1.29
2016-12-31 → 2023-12-31
Free Cash Flow·
2016-12-31 → 2023-12-31
Net margin-1507600.0%
2016-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend TLPH 5Y avg Peer Median Verdict
P/S (TTM) 58653.5 · 180.5 Overvalued
P/B (MRQ) 4.1 · 1.2 Overvalued
Price / Cash Flow -4.9 · · ·
Price / Tangible Book (MRQ) 10.55Y avg ≈3.6 ≈3.6 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 28.4%
Next Report Nov 10, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 12, 2026 $-0.06 $-0.07 11.8%
March 31, 2026 May 13, 2026 $-0.04 $-0.07 44.0%
Dec. 31, 2025 $-0.06 $-0.08 26.5%
Sept. 30, 2025 $-0.11 $-0.14 23.0%
June 30, 2025 $-0.10 $-0.10 2.0%
March 31, 2025 $-0.10 $-0.15 34.6%
Dec. 31, 2024 $-0.07 $-0.16 57.1%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 16
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $28.0K$0$651.0K$0$3M$5M$2M$2M$8M$17M$19M$5M
Cost of Revenue ···$3M$4M$6M$7M$4M$11M$12M$2M·
R&D Expense $6M$7M$6M$3M$4M$4M$5M$13M$19M$21M$22M$25M
SG&A Expense $7M$9M$12M$17M$31M$36M$45M$21M$17M$16M$14M$18M
Operating Expenses $14M$15M$18M$25M$39M$46M$56M$38M$47M$49M$39M$43M
Operating Income $-13M$-15M$-17M$-25M$-36M$-41M$-54M$-36M$-39M$-32M$-20M$-38M
Interest Expense ··$134.0K$1M$2M$3M$3M$2M$3M$3M$3M$3M
Other Non-op $-879.0K$2M$7M$84M$871.0K$588.0K$968.0K$-11M$-14M$-11M$-4M$4M
Pretax Income ··$-10M$59M$-35M$-40M$-53M$-47M$-52M$-43M$-24M$-33M
Income Tax $0$0$0$13.0K$5.0K$4.0K$3.0K$2.0K$-701.0K$-34.0K$760.0K$0
Net Income $-14M$-13M$-18M$48M$-35M$-40M$-53M$-47M$-52M$-43M$-24M$-33M
EPS (Basic) $-0.34$-0.50$-1.29$5.73$-5.86···$-1.10$-0.95$-0.55$-0.77
EPS (Diluted) ··$-1.29$5.72$-5.86···$-1.10$-0.95$-0.60$-0.91
Shares (Basic) 42,410,71125,845,63914,263,7447,385,3485,993,013···46,883,53545,313,11844,300,09943,427,111
Shares (Diluted) ··14,263,7447,406,9865,993,013···46,883,53545,313,11844,468,44044,322,297
EBITDA $-13M·$-17M··$-39M··$-37M$-30M$-18M$866.0K
Balance Sheet 27
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $6M$9M$6M$15M$8M$22M$15M$88M$53M$80M$108M$60M
Short-term Investments $14M$0$4M$495.0K$39M$16M$51M$18M$8M·$6M$15M
Receivables ···$309.0K$160.0K$635.0K$432.0K$49.0K$2M$6M$3M$0
Inventory ···$1M$1M$2M$3M$854.0K$956.0K$2M$466.0K·
Prepaid Expense $519.0K$554.0K$2M$2M$3M$2M$2M$1M$455.0K$756.0K$2M$948.0K
Current Assets $21M$9M$12M$25M$50M$47M$72M$108M$63M$89M$119M$76M
PP&E (Net) ···$10M$16M$16M$15M$11M$11M$11M$9M$10M
PP&E (Gross) ···$22M$27M$26M$24M$20M$19M$17M$13M$13M
Accum. Depreciation ···$12M$11M$11M$10M$9M$8M$7M$5M$3M
Intangibles $9M$9M$9M$9M$0·······
Other Non-current Assets ··$20.0K$166.0K$2M$656.0K$1M$705.0K$207.0K$50.0K··
Total Assets $30M$18M$20M$47M$78M$66M$91M$121M$76M$100M$128M$86M
Accounts Payable $544.0K$670.0K$1M$1M$2M$3M$2M$2M$1M$2M$2M$2M
Accrued Liabilities $3M$1M$2M$3M$7M$5M$6M$5M$4M$5M$4M$4M
Current Liabilities $4M$3M$5M$14M$19M$18M$14M$16M$14M$10M$13M$14M
Capital Leases ···$3M$4M$3M$4M·····
Other Non-current Liabilities ··$0$810.0K$81.0K$299.0K$490.0K$537.0K····
Total Liabilities $13M$10M$6M$26M$114M$122M$133M$116M$112M$105M$95M$40M
Long-term Debt ···$6M$14M$22M$25M$12M$19M$22M$21M$25M
Total Debt ··$0··$22M··$19M$22M$21M$25M
Common Stock $49.0K$17.0K$17.0K$8.0K$7.0K$98.0K$79.0K$78.0K$51.0K$45.0K$45.0K$43.0K
Paid-in Capital $489M$465M$458M$448M$438M$383M$357M$349M$261M$241M$236M$225M
Retained Earnings $-472M$-457M$-444M$-426M$-474M$-438M$-398M$-345M$-298M$-246M$-203M$-179M
AOCI ·········$3.0K$-1.0K$-4.0K
Stockholders' Equity $17M$8M$14M$22M$-36M$-56M$-41M$4M$-37M$-5M$33M$47M
Liabilities + Equity $30M$18M$20M$47M$78M$66M$91M$121M$76M$100M$128M$86M
Shares Outstanding 49,328,09717,029,46916,952,5198,243,6806,840,96798,812,00879,573,10178,757,93050,899,15445,333,79045,273,77243,712,363
Cash Flow 17
Metric Trend 202520242023202220212020201920182017201620152014
D&A ·$0$311.0K$2M$2M$2M$2M$575.0K$2M$2M$2M$866.0K
Stock-based Comp $699.0K$989.0K$2M$3M$5M$4M$5M$5M$4M$4M$5M$4M
Deferred Tax ·········$-1.0K··
Restructuring ···$500.0K·$500.0K····$756.0K·
Other Non-cash ··$-1M··$-4M··$16M$7M$-3M$-6M
Operating Cash Flow $-11M$-13M$-17M$-28M$-30M$-39M$-51M$-29M$-30M$-29M$-20M$-34M
CapEx ·$0$100.0K$364.0K$2M$2M$3M$819.0K$2M$4M$1M$6M
Investing Cash Flow $-14M$4M$-528.0K$36M$-26M$34M$-37M$-11M$-10M$2M$8M·
Debt Issued ·····$0$25M$0···$10M
Net Debt Issued ··$-5M··$-5M··$-4M·$-5M$10M
Stock Issued ····$45M$21M$1M$82M$16M···
Net Stock Activity ·····$21M··$16M···
Financing Cash Flow $23M$12M$3M$-507.0K$42M$17M$14M$75M$12M$-26.0K$60M·
Net Change in Cash $-3M$3M$-15M$8M$-15M$13M$-73M$35M$-27M$-28M$48M$-28M
Taxes Paid ·$0$0$13.0K$5.0K$-347.0K$-350.0K$2.0K$2.0K$-55.0K$782.0K·
Free Cash Flow ··$-18M··$-40M··$-32M$-33M$-21M$-40M
Levered FCF ··$-18M··$-44M··$-35M$-36M$-24M$-43M
Profitability 7
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin -48157.1%·-2594.3%··-756.3%··-483.8%-184.1%-103.6%·
Net Margin -51035.7%·-2826.0%··-745.5%··-644.2%-248.6%-126.7%-639.3%
Pretax Margin ··-1580.2%··-745.5%··-653.0%-248.8%-122.7%-721.7%
EBITDA Margin -48157.1%·-2546.5%··-722.1%··-462.0%-172.3%-93.3%16.6%
ROA -59.6%·-54.2%··-51.2%··-58.7%-37.9%-22.8%-34.0%
ROE -120.8%·-113.5%··71.1%··246.2%-310.8%-61.2%-55.7%
ROIC ··-119.7%··120.9%··219.2%-197.0%-38.1%·
Liquidity & Solvency 5
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 5.5·2.6··2.7··4.68.79.35.6
Quick Ratio 5.4·2.1··2.5··4.58.59.15.5
Debt / Equity ··0.0··-0.4··-0.5-4.00.60.5
LT Debt / Equity ·····-0.2··-0.3-3.50.50.4
Interest Coverage ··-126.0··-12.4··-11.7-11.5-6.7·
Efficiency 3
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 0.0·0.0··0.1··0.10.20.20.1
Inventory Turnover ·····2.5··6.99.47.6·
Receivables Turnover ·····10.2··2.23.811.7·
Per Share 5
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $0.35·$0.83··$-0.56··$-0.72$-0.12$0.73$1.07
Revenue / Share ··$0.05·····$0.17$0.38$0.43$0.12
Cash Flow / Share ··$-1.23·····$-0.63$-0.65$-0.45$-0.78
Cash / Share $0.12·$0.34··$0.28··$1.04$1.77$2.38$1.37
EPS (TTM) ··$-1.29$5.72$-5.86$-1.11$-1.11$-1.11$-1.10$-0.95$-0.60$-0.91
Growth Rates 3
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY ····-48.0%·······
Revenue CAGR 3Y ··-50.6%·········
Revenue CAGR 5Y -65.1%···········
Valuation (TTM) 14
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $28.0K$0$651.0K$0$3M$5M$2M$2M$8M$17M$19M$5M
Net Income TTM $-14M$-13M$-18M$48M$-35M$-40M$-53M$-47M$-52M$-43M$-24M$-33M
Market Cap $56M·$13M··$2.45B··$2.07B$2.36B$3.49B$5.88B
Enterprise Value ··$3M··$2.43B··$2.03B$2.30B$3.39B$5.83B
P/E ··-0.60.4-1.9-22.3-38.0-41.6-36.9-54.7-128.3-147.9
P/S 2008.4·19.3··452.5··258.5135.8181.01127.8
P/B 3.3·0.9··-44.0··-56.6-441.7105.3126.1
P / Tangible Book 6.8·2.41.4········
P / Cash Flow -4.9·-0.7··-63.6··-69.4-80.2-174.7-170.8
P / FCF ··-0.7··-60.7··-64.2-71.2-162.8-147.2
EV / EBITDA ··-0.2··-62.1··-54.8-76.9-188.86735.8
EV / FCF ··-0.2··-60.2··-63.0-69.4-158.5-146.0
EV / Revenue ··4.9··448.6··253.3132.4176.21118.1
Earnings Yield ··-174.3%253.1%-52.3%-4.5%-2.6%-2.4%-2.7%-1.8%-0.78%-0.68%

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $28.0K $0 $651.0K $0 $3M
Operating Margin % -48157.1% · -2594.3% · ·
Net Income $-14M $-13M $-18M $48M $-35M
Diluted EPS · · $-1.29 $5.72 $-5.86

Institutional owners (13F) 56 filers · $25.3M total · As of June 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 56
Value held $25.3M
New positions 12
Exited positions 7
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
12 (-1 vs prior Q) 7 (+4 vs prior Q) 15 (0 vs prior Q) 9 (-1 vs prior Q) +2.0M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Rosalind Advisors, Inc. $5,324,586 5,169,501 21.04% Shares
AIGH Capital Management LLC $4,739,547 4,601,502 18.72% Shares
Rock Springs Capital Management LP $3,696,862 3,589,186 14.60% Shares
Nantahala Capital Management, LLC $3,597,295 3,492,519 14.21% Shares
Bleichroeder LP $1,347,021 1,307,787 5.32% Shares
CANTOR FITZGERALD, L. P. $914,105 887,481 3.61% Shares
Dauntless Investment Group, LLC $768,433 746,051 3.04% Shares
VANGUARD GROUP INC $756,593 663,677 2.99% Shares
VANGUARD CAPITAL MANAGEMENT LLC $722,933 701,877 2.86% Shares
Caption Management, LLC $530,418 514,969 2.10% Shares
Almitas Capital LLC $481,167 467,152 1.90% Shares
GEODE CAPITAL MANAGEMENT, LLC $442,001 429,062 1.75% Shares
Shay Capital LLC $417,937 405,764 1.65% Shares
VANGUARD FIDUCIARY TRUST CO $229,043 222,372 0.90% Shares
DIADEMA PARTNERS LP $158,170 153,563 0.62% Shares
UBS Group AG $133,814 129,916 0.53% Shares
RENAISSANCE TECHNOLOGIES LLC $116,699 113,300 0.46% Shares
Mariner, LLC $103,000 100,000 0.41% Shares
BlackRock, Inc. $94,294 91,548 0.37% Shares
NORTHERN TRUST CORP $90,945 88,296 0.36% Shares
Values First Advisors, Inc. $82,076 79,685 0.32% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $77,962 75,691 0.31% Shares
CITADEL ADVISORS LLC $61,594 59,800 0.24% Put option
CITADEL ADVISORS LLC $60,564 58,800 0.24% Call option
Universal- Beteiligungs- und Servicegesellschaft mbH $51,500 50,000 0.20% Shares
Persistent Asset Partners Ltd $40,137 38,968 0.16% Shares
Vanguard Global Advisers, LLC $30,551 29,661 0.12% Shares
GOLDMAN SACHS GROUP INC $29,288 28,435 0.12% Shares
JANE STREET GROUP, LLC $29,149 28,300 0.12% Put option
XTX Topco Ltd $29,040 28,194 0.11% Shares
STATE STREET CORP $22,847 22,182 0.09% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $22,660 22,000 0.09% Call option
JANE STREET GROUP, LLC $20,085 19,500 0.08% Call option
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $18,250 12,500 0.07% Shares
TWO SIGMA SECURITIES, LLC $16,262 15,788 0.06% Shares
STEPHENS INC /AR/ $15,587 15,133 0.06% Shares
Onyx Bridge Wealth Group LLC $11,845 11,500 0.05% Shares
JANE STREET GROUP, LLC $10,974 10,654 0.04% Shares
GROUP ONE TRADING LLC $8,459 8,213 0.03% Shares
JPMORGAN CHASE & CO $4,771 4,544 0.02% Shares
Steward Partners Investment Advisory, LLC $1,030 1,000 0.00% Shares
BARCLAYS PLC $990 961 0.00% Shares
WELLS FARGO & COMPANY/MN $618 600 0.00% Shares
OSAIC HOLDINGS, INC. $293 285 0.00% Shares
GSA CAPITAL PARTNERS LLP $216 209,355 0.00% Shares
NewEdge Advisors, LLC $207 201 0.00% Shares
Silicon Valley Capital Partners $141 137 0.00% Shares
BNP PARIBAS FINANCIAL MARKETS $140 136 0.00% Shares
SBI Securities Co., Ltd. $118 115 0.00% Shares
Arax Advisory Partners $83 81 0.00% Shares

Show all 56 institutional owners →

Activists & 5%+ owners 5 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Nantahala Capital Management, LLC, Wilmot B. Harkey, Daniel Mack ×3 filings April 3, 2025 11.70% Amendment · SEC
Three Arch Partners IV, L.P. (the “ TAP IV ”), Three Arch Associates IV, L.P. (“ TAA IV ”), Three Arch Management IV, L.L.C. (“ TAM IV ”), Three Arch Partners III, L.P. (the “ TAP III ”), Three Arch Associates III, L.P. (“ TAA III ”), Three Arch Management III, L.L.C. (“ TAM III ”), Mark Wan (“ Wan ”), Wilfred Jaeger (“ Jaeger ”) ×7 filings May 24, 2018 · Initial filing · SEC
ACP IV, L.P., ACMP IV, LLC, Guy Nohra, Daniel Janney June 17, 2015 · Initial filing · SEC
ACP IV, L.P. (2), ACMP IV, LLC (2), Guy Nohra (2), Daniel Janney (2), David Mack (2) ×2 filings Dec. 18, 2012 · Initial filing · SEC
Skyline Venture Partners Qualified Purchaser Fund IV, L.P., Skyline Venture Management IV, LLC, John G. Freund, Yasunori Kaneko, Stephen J. Hoffman Feb. 28, 2011 · Initial filing Passive investment SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 25 insiders · 10 officers · 15 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Vincent J. Angotti CHIEF EXECUTIVE OFFICER April 2, 2026 F 790,767 2 0 $211,198
Raffi Asadorian Chief Financial Officer April 2, 2026 F 85,879 1 0 $36,450
Timothy E Morris Chief Financial Officer Feb. 7, 2017 A · 0 0 $0
James H Welch Chief Financial Officer Feb. 4, 2014 A 15,000 0 0 $0
Shakil Aslam Chief Medical Officer May 20, 2026 F 76,542 1 0 $28,350
Pamela P Palmer Chief Medical Officer March 3, 2024 F 59,149 0 0 $0
Lawrence G Hamel Chief Development Officer Feb. 11, 2020 F 127,769 0 0 $0
John G. Saia General Counsel and Secretary April 16, 2018 A · 0 0 $0
Jane Wright Mitchell Chief Legal Officer Feb. 7, 2017 A · 0 0 $0
David Chung Chief Commercial Officer Feb. 4, 2014 A · 0 0 $0
Abhinav Jain Director June 22, 2026 A 12,412 0 0 $0
Marina Bozilenko Director June 22, 2026 A 14,147 0 0 $0
Joseph Todisco Director June 22, 2026 A 11,497 0 0 $0
Jill Marie Broadfoot Director June 22, 2026 A 13,647 0 0 $0
Adrian Adams Director June 22, 2026 A 22,709 0 0 $0
WAN MARK A Director June 22, 2026 A 13,959 0 0 $0
Stephen J Hoffman Director June 22, 2026 A 13,959 0 0 $0
Richard Afable Director Oct. 10, 2023 A 2,468 0 0 $0
Howard B Rosen Director Oct. 10, 2023 A 5,293 0 0 $0
Mark G Edwards Director June 17, 2021 A 261,250 0 0 $0
Steven C Hoffman Director June 14, 2018 A · 0 0 $0
Richard King Director March 2, 2014 F 134,567 0 0 $0
Guy P Nohra Director Sept. 20, 2013 S 2,507,974 0 0 $0
Thomas A Schreck Director July 24, 2012 A 17,982 0 0 $0
Badri N Dasu · April 2, 2026 F 71,440 1 0 $28,350

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 2 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
VXF · VANGUARD INDEX FUNDS 0.00% 440,104 SH Aug. 19, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 261,773 SH Aug. 19, 2026 Daily

TLPH Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 9 analysts BUY
Median target $3.00 +165.5%
2 22.2% Strong Buy
6 66.7% Buy
1 11.1% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

4 analysts · 2026-10-01

Mean target $3.12 +176.5%

← Below all targets Current price $1.13
Low$3.00 Mean$3.12 High$3.50

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
TLPH $56M · · -51035.7% -120.8% ·
RFL · -1.6 44.0% -3328.2% -34.6% ·
CING · · · · · ·
PLRX $75M -0.5 -83.7% · -74.4% ·
ELOX · · · · 30.1% ·
HYPD $31M -0.4 1318.8% -5570.6% -115.6% 62.7%
IMA · -0.7 -77.1% -5668.6% 192.1% ·
SCYX $28M -3.7 450.0% -41.8% -18.4% ·
LLY · 46.8 44.7% 31.7% 101.2% ·

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 12, 2026