NKTR Nektar Therapeutics - Common Stock

NASDAQ · Pharmaceuticals · Voir sur SEC EDGAR ↗
$75,92
Prix · Aoû 19, 2026
Données fondamentales au Aoû 14, 2026

À propos de Nektar Therapeutics - Common Stock Présentation de l'entreprise depuis Wikipedia

Nektar Therapeutics is an American biopharmaceutical company. The company was founded in 1990 and is based in San Francisco, California. The company develops new drug candidates by applying its proprietary PEGylation and advanced polymer conjugate technologies to modify chemical structure of substances, which improves drug characteristics like retention and solubility. It is a technology supplier to a number of pharmaceutical companies including Affymax, Amgen, Merck, Pfizer and UCB Pharma, etc. The company developed the world's first inhalable non-injectable insulin, Exubera, which was awarded as the bronze award by Wall Street Journal for its technological breakthrough.

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Nektar Therapeutics is an American biopharmaceutical company. The company was founded in 1990 and is based in San Francisco, California. The company develops new drug candidates by applying its proprietary PEGylation and advanced polymer conjugate technologies to modify chemical structure of substances, which improves drug characteristics like retention and solubility. It is a technology supplier to a number of pharmaceutical companies including Affymax, Amgen, Merck, Pfizer and UCB Pharma, etc. The company developed the world's first inhalable non-injectable insulin, Exubera, which was awarded as the bronze award by Wall Street Journal for its technological breakthrough.

Background

The company is engaged in developing a proprietary pipeline of drug candidates for several therapeutic areas including oncology, pain, anti-infectives, anti-viral and immunology. The company's research and development involve in small molecule and biologic drug candidates. Its drug candidate base consists of naloxegol (Movantik), a Phase III oral opioid antagonist, etirinotecan pegol, a topoisomerase inhibitor under Phase III clinical study as of 2012, NKTR 061, NKTR-181, NKTR-214, etc.

In 2013, the company was assigned a patent which was developed by the company and other four co-inventors. The products of the company is served as a supplement to improve the pharmacokinetics, pharmacodynamics, half-life, bioavailability and other areas of drugs for the patients worldwide. As of March 2014, the company had a market capitalization of $1.7 billion with an enterprise value of $1.67 billion.

As of December 2024, at a stock price-per-share of roughly $1, the market cap is roughly $171 million. Nektar underwent periods of downsizing after unsuccessful partnerships were ended with Eli Lilly in 2023 and Bristol Myers Squibb in 2022, resulting in layoffs of most company employees.

Pipeline

Etirinotecan pegol was in the phase III BEACON trial as well as in the I-SPY2 adaptive clinical trial for breast cancer in 2016. The European Medicines Agency refused a marketing authorisation in 2017.

Bempegaldesleukin (NKTR-214) is a CD122-biased immune-stimulatory cytokine, Phase I results were announced in November 2016. It is now in a phase 2 trial in combination with nivolumab for various advanced cancers.

In 2023 Nektar's partnership with Eli Lilly in development of "rezpeg" was ended. Eli Lilly claimed the drug lacked suitable efficacy, while Nektar responded that Eli Lilly had botched the analysis.

Source : Wikipedia (Anglais), CC BY-SA 4.0 · Voir sur Wikipedia ↗

Wikidata ↗

NKTR Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines

Prix
$75.92
Capitalisation Boursière
$2.24B
P/E (TTM)
-11.3
BPA (TTM)
$-9.73
Revenus (TTM)
$55M
Rendement div.
ROE
-500.1%
Dette/Capitaux propres
Fourchette 52 semaines
$25 – $109

NKTR Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue

Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA

Revenus et bénéfice net $55M
10-point trend, -66.6%
2016-12-31 2025-12-31
BPA $-9.73
10-point trend, -784.5%
2016-12-31 2025-12-31
Flux de trésorerie libre $-209M
10-point trend, -69.1%
2016-12-31 2025-12-31
Marges -297.1%

Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?

Métrique
Tendance sur 5 ans
NKTR
Médiane des pairs
P/E (TTM)
5-point trend, +93.9%
-11.3
29.4
P/S (TTM)
5-point trend, -95.8%
40.5
4.9
P/B
5-point trend, -82.7%
24.9
6.5
Price / FCF (Cours / FCF)
5-point trend, +95.3%
-10.7

Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC

Métrique
Tendance sur 5 ans
NKTR
Médiane des pairs
Operating Margin (Marge d'exploitation)
5-point trend, +42.1%
-253.7%
Net Profit Margin (Marge nette)
5-point trend, +42.2%
-297.1%
-9.0%
ROA
5-point trend, -42.4%
-56.2%
-8.2%
ROE
5-point trend, -606.9%
-500.1%
-19.4%
ROIC
5-point trend, -137.1%
-155.8%

Santé financière Dette, liquidité, solvabilité — solidité du bilan

Métrique
Tendance sur 5 ans
NKTR
Médiane des pairs
Current Ratio (Ratio de liquidité)
5-point trend, -46.7%
5.0
3.6
Quick Ratio (Ratio de liquidité réduite)
5-point trend, -49.6%
0.3

Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans

Métrique
Tendance sur 5 ans
NKTR
Médiane des pairs
Revenue YoY (Chiffre d'affaires YoY)
5-point trend, -45.8%
-43.9%
Revenue CAGR 3Y (CAGR du chiffre d'affaires 3 ans)
5-point trend, -45.8%
-15.7%
Revenue CAGR 5Y (CAGR du chiffre d'affaires 5 ans)
5-point trend, -45.8%
-18.4%

Indicateurs par action BPA, valeur comptable par action, flux de trésorerie par action, dividende par action

Métrique
Tendance sur 5 ans
NKTR
Médiane des pairs
EPS (Diluted) (BPA (Dilué))
5-point trend, -240.2%
$-9.73

Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances

Métrique
Tendance sur 5 ans
NKTR
Médiane des pairs

NKTR Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse

ACHAT 17 analystes
  • Achat fort 7 41,2%
  • Achat 8 47,1%
  • Conserver 2 11,8%
  • Vente 0 0,0%
  • Vente forte 0 0,0%

Objectif de cours à 12 mois

9 analystes · 2026-08-16
Objectif médian $151.00 +98,9%
Objectif moyen $153.22 +101,8%

Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats

Surprise Moyenne
0.21%
Période EPS Actual BPA est. Surprise
30 juin 2026 $-1.23 $-2.02 0.79%
31 mars 2026 $-1.82 $-1.63 -0.19%
31 décembre 2025 $-1.78 $-2.52 0.74%
30 septembre 2025 $-1.87 $-2.74 0.87%
30 juin 2025 $-2.95 $-3.10 0.15%
31 mars 2025 $-3.60 $-2.51 -1.1%

Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur

Ticker Capitalisation Boursière P/E Revenus Année/Année Marge Nette ROE Marge Brute
NKTR $862M -4.3 -43.9% -297.1% -500.1%
ALMS -3.4 -1011.8% -61.9%
SUPN $2.86B -73.1 8.6% -5.4% -3.6%
ATAI $223M -1.4 -1.9% -48464.0% -83.1%
TRVI $1.61B -39.1 -22.4%
NUVB $3.03B -14.9 699.0% -325.3% -60.3%
OCUL $2.62B -8.5 -18.5% -511.9% -55.4%
PBH $3.33B 15.2 -4.3% 17.5% 10.2% 54.7%
AMRX 57.3 8.1% 2.4% -80.0% 36.9%
RAPP $1.45B -10.6 -29.8%
HRMY $2.16B 13.8 21.5% 18.3% 19.3% 77.2%

Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie

Compte de résultat 17
Données annuelles Compte de résultat pour NKTR
Métrique Tendance 202520242023202220212020201920182017201620152014
Revenue 12-point trend, -72.5% $55M $98M $90M $92M $102M $153M $115M $1.19B $308M $165M $231M $201M
Cost of Revenue 12-point trend, -100.0% $0 $31M $34M $22M $25M $19M $21M $24M $31M $30M $34M $29M
R&D Expense 12-point trend, -20.6% $117M $121M $114M $218M $400M $409M $435M $400M $268M $204M $183M $148M
SG&A Expense 12-point trend, +67.8% $69M $77M $77M $92M $123M $105M $99M $81M $52M $44M $43M $41M
Operating Expenses 12-point trend, -10.1% $195M $204M $354M $468M $548M $578M $555M $505M $367M $278M $260M $217M
Operating Income 12-point trend, -749.9% $-140M $-105M $-264M $-376M $-446M $-425M $-440M $688M $-60M $-113M $-29M $-16M
Interest Expense 9-point trend, -100.0% · · · $0 $0 $7M $21M $22M $22M $22M $18M $18M
Interest Income 5-point trend, +282.2% $10M $14M $19M $7M $3M · · · · · · ·
Other Non-op 12-point trend, -55.7% $361.0K $-390.0K $-6M $-116.0K $-162.0K $18M $46M $38M $5M $2M $2M $814.0K
Pretax Income 12-point trend, -201.7% $-164M $-119M $-276M $-365M $-523M $-444M $-440M $683M $-96M $-153M $-81M $-54M
Income Tax 12-point trend, +73.0% $-138.0K $-239.0K $-200.0K $3M $557.0K $493.0K $613.0K $1M $616.0K $876.0K $506.0K $-512.0K
Net Income 12-point trend, -204.3% $-164M $-119M $-276M $-368M $-524M $-444M $-441M $681M $-97M $-154M $-81M $-54M
EPS (Basic) 10-point trend, -784.5% $-9.73 $-8.68 $-1.45 $-1.97 $-2.86 $-2.49 $-2.52 $4.02 $-0.62 $-1.10 · ·
EPS (Diluted) 10-point trend, -784.5% $-9.73 $-8.68 $-1.45 $-1.97 $-2.86 $-2.49 $-2.52 $3.78 $-0.62 $-1.10 · ·
Shares (Basic) 10-point trend, -87.9% 16,870,930 13,710,775 190,001,000 187,138,000 183,298,000 178,581,000 174,993,000 169,600,000 155,953,000 139,596,000 · ·
Shares (Diluted) 10-point trend, -87.9% 16,870,930 13,710,775 190,001,000 187,138,000 183,298,000 178,581,000 174,993,000 180,119,000 155,953,000 139,596,000 · ·
EBITDA 11-point trend, -377.0% $-140M $-101M $-257M $-364M $-433M $-413M $-429M $697M $-47M $-113M $-29M ·
Bilan 24
Données annuelles Bilan pour NKTR
Métrique Tendance 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +22.2% $15M $44M $35M $88M $25M $199M $96M $195M $5M $60M $56M $12M
Short-term Investments 4-point trend, +29.2% · · · · · · · · $291M $329M $253M $225M
Receivables 11-point trend, -100.0% · $0 $1M $6M $22M $39M $37M $43M $5M $16M $20M $4M
Inventory 12-point trend, -100.0% $0 $0 $16M $19M $16M $15M $13M $11M $11M $11M $11M $13M
Other Current Assets 12-point trend, +132.7% $21M $6M $10M $16M $23M $22M $15M $21M $8M $10M $10M $9M
Current Assets 12-point trend, -7.6% $266M $261M $331M $546M $796M $1.14B $1.42B $1.44B $327M $426M $350M $288M
PP&E (Net) 12-point trend, -97.1% $2M $3M $19M $32M $61M $60M $66M $49M $47M $66M $71M $70M
Accum. Depreciation 11-point trend, -83.0% · $16M $87M $125M $148M $138M $128M $121M $115M $111M $103M $94M
Goodwill 10-point trend, -100.0% · · $0 $77M $77M $77M $77M $77M $77M $77M $77M $77M
Other Non-current Assets 12-point trend, +115.8% $14M $5M $5M $2M $3M $1M $344.0K $4M $994.0K $817.0K $754.0K $7M
Total Assets 12-point trend, -36.5% $280M $304M $398M $711M $1.12B $1.54B $1.98B $2.15B $509M $569M $499M $442M
Accounts Payable 12-point trend, +298.4% $11M $12M $10M $13M $10M $22M $19M $6M $5M $3M $2M $3M
Accrued Liabilities 5-point trend, +247.0% $22M $30M $22M $37M · · · · · · · $6M
Current Liabilities 12-point trend, -16.4% $54M $61M $51M $68M $85M $116M $354M $82M $56M $72M $61M $64M
Capital Leases 11-point trend, +1476.6% $65M $83M $99M $113M $126M $136M $143M $0 · $2M $1M $4M
Other Non-current Liabilities 12-point trend, -41.4% $9M $7M $5M $8M $4M $9M $768.0K $10M $6M $7M $10M $15M
Total Liabilities 12-point trend, -53.0% $191M $243M $267M $344M $438M $461M $572M $433M $421M $481M $492M $405M
Common Stock 12-point trend, -84.6% $2.0K $1.0K $19.0K $19.0K $19.0K $18.0K $17.0K $17.0K $15.0K $15.0K $13.0K $13.0K
Retained Earnings 12-point trend, -110.5% $-3.76B $-3.60B $-3.48B $-3.20B $-2.83B $-2.31B $-1.86B $-1.42B $-2.12B $-2.02B $-1.87B $-1.79B
Treasury Stock 2-point trend, +3000000.00 · $3M $0 · · · · · · · · ·
AOCI 12-point trend, +101.1% $17.0K $61.0K $80.0K $-7M $-4M $-2M $-1M $-6M $-2M $-2M $-2M $-2M
Stockholders' Equity 12-point trend, +147.3% $90M $61M $131M $367M $680M $1.08B $1.41B $1.72B $88M $88M $6M $36M
Liabilities + Equity 12-point trend, -36.5% $280M $304M $398M $711M $1.12B $1.54B $1.98B $2.15B $509M $569M $499M $442M
Shares Outstanding 12-point trend, -84.5% 20,378,832 12,385,001 12,757,984 188,560,000 185,468,000 180,091,000 176,505,000 173,530,000 159,524,000 153,212,000 135,289,000 131,216,000
Flux de trésorerie 14
Données annuelles Flux de trésorerie pour NKTR
Métrique Tendance 202520242023202220212020201920182017201620152014
D&A 12-point trend, -92.1% $1M $4M $7M $12M $13M $12M $11M $9M $13M $13M $11M $13M
Stock-based Comp · · · · · · · · · · · $17M
Deferred Tax 12-point trend, +306.5% $64.0K $-10.0K $-140.0K $3M $-102.0K $-36.0K $-21.0K $93.0K $35.0K $-115.0K $-22.0K $-31.0K
Other Non-cash 8-point trend, -1770.0% · $-61M $77M $49M $98M $119M $101M $28M $4M · · ·
Operating Cash Flow 12-point trend, -46.8% $-209M $-176M $-193M $-304M $-413M $-313M $-329M $718M $-80M $-117M $-73M $-142M
CapEx 12-point trend, -98.3% $171.0K $1M $865.0K $6M $15M $7M $26M $14M $10M $6M $11M $10M
Investing Cash Flow 10-point trend, +98.5% $-1M $143M $140M $366M $203M $496M $207M $-1.38B $-29M $-82M · ·
Stock Repurchased 3-point trend, +0.00 $0 $3M $0 · · · · · · · · ·
Net Stock Activity 2-point trend, +100.0% $0 $-3M · · · · · · · · · ·
Financing Cash Flow 10-point trend, -11.3% $181M $42M $30.0K $2M $36M $-80M $23M $852M $54M $204M · ·
Net Change in Cash 12-point trend, -9.1% $-29M $9M $-53M $63M $-174M $103M $-99M $190M $-55M $4M $43M $-27M
Taxes Paid 12-point trend, -120.2% $-195.0K $76.0K $3M $272.0K $325.0K $539.0K $555.0K $618.0K $556.0K $757.0K $860.0K $964.0K
Free Cash Flow 11-point trend, -147.6% $-209M $-177M $-193M $-310M $-428M $-321M $-355M $704M $-90M $-123M $-84M ·
Levered FCF 8-point trend, -201.6% · · · $-310M $-428M $-327M $-376M $682M $-112M $-146M $-103M ·
Rentabilité 7
Données annuelles Rentabilité pour NKTR
Métrique Tendance 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, -1892.6% -253.7% -106.9% -292.6% -408.6% -437.8% -278.0% -383.9% 57.6% -19.4% -68.2% -12.7% ·
Net Margin 11-point trend, -744.7% -297.1% -120.9% -306.3% -400.0% -514.0% -290.6% -384.5% 57.1% -31.4% -92.8% -35.2% ·
Pretax Margin 11-point trend, -750.5% -297.3% -121.1% -306.5% -396.5% -513.5% -290.3% -383.9% 57.2% -31.2% -92.3% -35.0% ·
EBITDA Margin 11-point trend, -1892.6% -253.7% -102.7% -284.8% -395.4% -425.0% -269.8% -374.3% 58.4% -15.3% -68.2% -12.7% ·
ROA 11-point trend, -226.6% -56.2% -33.9% -49.8% -40.3% -39.5% -25.3% -21.3% 51.2% -17.9% -28.8% -17.2% ·
ROE 11-point trend, -31.7% -500.1% -217.0% -190.2% -94.5% -70.7% -39.5% -30.4% 38.9% -109.9% -324.7% -379.7% ·
ROIC 11-point trend, +66.1% -155.8% -172.9% -201.2% -103.5% -65.7% -39.5% -31.4% 40.0% -68.3% -128.8% -459.7% ·
Liquidité et Solvabilité 3
Données annuelles Liquidité et Solvabilité pour NKTR
Métrique Tendance 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, -13.0% 5.0 4.3 6.5 8.0 9.3 9.8 4.0 17.5 5.8 5.9 5.7 ·
Quick Ratio 11-point trend, -94.7% 0.3 0.7 0.7 1.4 0.6 2.1 0.4 2.9 5.4 5.6 5.4 ·
Interest Coverage 6-point trend, -3762.2% · · · · · -62.1 -20.6 31.9 -2.7 -5.0 -1.6 ·
Efficacité 3
Données annuelles Efficacité pour NKTR
Métrique Tendance 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, -61.3% 0.2 0.3 0.2 0.1 0.1 0.1 0.1 0.9 0.6 0.3 0.5 ·
Inventory Turnover 10-point trend, +35.8% · 3.8 1.9 1.2 1.6 1.4 1.8 2.2 2.8 2.7 2.8 ·
Receivables Turnover 10-point trend, +733.7% · 163.4 25.1 6.5 3.3 4.0 2.9 49.5 29.7 9.3 19.6 ·
Par action 5
Données annuelles Par action pour NKTR
Métrique Tendance 202520242023202220212020201920182017201620152014
Book Value / Share 11-point trend, +9180.2% $4.41 $0.33 $0.68 $1.94 $3.66 $5.98 $7.96 $9.90 $0.55 $0.58 $0.05 ·
Revenue / Share 8-point trend, -50.6% $3.27 $0.48 $0.47 $0.49 $0.56 $0.86 $0.66 $6.63 · · · ·
Cash Flow / Share 8-point trend, -410.0% $-12.36 $-0.85 $-1.01 $-1.62 $-2.25 $-1.75 $-1.88 $3.99 · · · ·
Cash / Share 11-point trend, +80.6% $0.74 $0.24 $0.18 $0.47 $0.14 $1.10 $0.55 $1.12 $0.03 $0.39 $0.41 ·
EPS (TTM) 12-point trend, -2062.2% $-9.73 $-8.68 $-1.45 $-1.97 $-2.86 $-2.49 $-2.52 $3.78 $-0.62 $-1.10 $-0.61 $-0.45
Taux de croissance 3
Données annuelles Taux de croissance pour NKTR
Métrique Tendance 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, -31.6% -43.9% 9.2% -2.1% -9.7% -33.4% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +3.1% -15.7% -1.1% -16.2% · · · · · · · · ·
Revenue CAGR 5Y -18.4% · · · · · · · · · · ·
Valorisation (TTM) 10
Données annuelles Valorisation (TTM) pour NKTR
Métrique Tendance 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, -72.5% $55M $98M $90M $92M $102M $153M $115M $1.19B $308M $165M $231M $201M
Net Income TTM 12-point trend, -204.3% $-164M $-119M $-276M $-368M $-524M $-444M $-441M $681M $-97M $-154M $-81M $-54M
Market Cap 11-point trend, -97.5% $862M $2.59B $1.61B $6.39B $37.59B $45.92B $57.16B $85.56B $142.90B $28.20B $34.19B ·
P/E 12-point trend, +99.2% -4.3 -1.6 -5.8 -17.2 -70.9 -102.4 -128.5 130.4 -1444.8 -167.3 -414.3 -516.7
P/S 11-point trend, -89.5% 15.6 26.3 17.8 69.4 368.8 300.3 498.7 71.7 464.4 170.5 148.2 ·
P/B 11-point trend, -99.8% 9.6 42.7 12.3 17.4 55.3 42.6 40.7 49.8 1627.1 320.0 5318.8 ·
P / Tangible Book 6-point trend, -79.1% 9.6 42.7 12.3 22.0 62.3 45.9 · · · · · ·
P / Cash Flow 11-point trend, +99.1% -4.1 -14.7 -8.3 -21.0 -91.1 -146.6 -173.9 119.1 -1777.1 -241.0 -467.9 ·
P / FCF 11-point trend, +99.0% -4.1 -14.6 -8.3 -20.6 -87.9 -143.3 -161.0 121.5 -1586.2 -228.5 -405.7 ·
Earnings Yield 12-point trend, -12010.5% -23.0% -62.2% -17.3% -5.8% -1.4% -0.98% -0.78% 0.77% -0.07% -0.60% -0.24% -0.19%

États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années

Compte de résultat
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenu $55M$98M$90M$92M$102M
Marge d'exploitation % -253.7%-106.9%-292.6%-408.6%-437.8%
Résultat net $-164M$-119M$-276M$-368M$-524M
BPA dilué $-9.73$-8.68$-1.45$-1.97$-2.86
Bilan
2025-12-312024-12-312023-12-312022-12-312021-12-31
Ratio de liquidité 5.04.36.58.09.3
Ratio de liquidité réduite 0.30.70.71.40.6
Flux de trésorerie
2025-12-312024-12-312023-12-312022-12-312021-12-31
Flux de trésorerie libre $-209M$-177M$-193M$-310M$-428M

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Détenteurs institutionnels (13F) 270 déclarants · $2.1B total · Au 30 juin 2026

Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.

Activité institutionnelle — Q2 2026 vs trimestre précédent
Nouvelles positions Positions clôturées Augmenté Diminué Variation nette des actions
88 (+12 vs T. préc.) 41 (+10 vs T. préc.) 91 (+20 vs T. préc.) 48 (-8 vs T. préc.) +7.0M

Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.

Institution Valeur Actions % de 13F suivies Type
Two Seas Capital LP $215 868 856 3 092 234 10,35% Actions
FMR LLC $192 088 149 2 751 585 9,21% Actions
BVF INC/IL $166 920 946 2 391 075 8,00% Actions
VANGUARD CAPITAL MANAGEMENT LLC $104 495 029 1 496 849 5,01% Actions
TWO SIGMA INVESTMENTS, LP $83 911 899 1 202 004 4,02% Actions
Vestal Point Capital, LP $69 810 000 1 000 000 3,35% Actions
STATE STREET CORP $63 504 691 909 679 3,04% Actions
SUSQUEHANNA INTERNATIONAL GROUP, LLP $57 502 497 823 700 2,76% Option d'achat
Prosight Management, LP $56 546 100 810 000 2,71% Actions
GEODE CAPITAL MANAGEMENT, LLC $52 759 799 755 586 2,53% Actions
ARMISTICE CAPITAL, LLC $50 542 440 724 000 2,42% Actions
GILDER GAGNON HOWE & CO LLC $41 946 944 600 873 2,01% Actions
MILLENNIUM MANAGEMENT LLC $33 377 557 478 120 1,60% Actions
BRAIDWELL LP $33 063 203 473 617 1,59% Actions
Sofinnova Investments, Inc. $32 933 775 471 763 1,58% Actions
Woodline Partners LP $32 871 784 470 875 1,58% Actions
ORBIMED ADVISORS LLC $32 485 804 465 346 1,56% Actions
SUSQUEHANNA INTERNATIONAL GROUP, LLP $27 540 045 394 500 1,32% Option de vente
EMERALD ADVISERS, LLC $27 236 930 390 158 1,31% Actions
VANGUARD PORTFOLIO MANAGEMENT LLC $24 331 577 348 540 1,17% Actions
DAFNA Capital Management LLC $22 226 108 318 380 1,07% Actions
Deep Track Capital, LP $20 943 000 300 000 1,00% Actions
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $19 893 826 284 971 0,95% Actions
22NW, LP $19 624 638 281 115 0,94% Actions
SUSQUEHANNA INTERNATIONAL GROUP, LLP $19 475 384 278 977 0,93% Actions
PRIMECAP MANAGEMENT CO/CA/ $19 047 658 272 850 0,91% Actions
Nearwater Capital Markets, Ltd $18 255 315 261 500 0,88% Actions
BARCLAYS PLC $17 968 815 257 396 0,86% Actions
EMERALD MUTUAL FUND ADVISERS TRUST $17 842 528 255 587 0,86% Actions
ADAR1 Capital Management, LLC $17 046 485 244 184 0,82% Actions
Creek Drive Management Group LLC $16 963 830 243 000 0,81% Actions
SEVEN GRAND MANAGERS, LLC $16 754 400 240 000 0,80% Actions
VANGUARD FIDUCIARY TRUST CO $16 724 731 239 575 0,80% Actions
NORGES BANK $15 030 093 215 300 0,72% Actions
Bronte Capital Management Pty Ltd. $13 852 678 198 434 0,66% Actions
TWO SIGMA ADVISERS, LP $13 039 744 308 414 0,63% Actions
CITADEL ADVISORS LLC $12 251 655 175 500 0,59% Option de vente
GREAT POINT PARTNERS LLC $12 216 750 175 000 0,59% Actions
Caption Management, LLC $11 944 491 171 100 0,57% Option d'achat
MILLENNIUM MANAGEMENT LLC $11 867 700 170 000 0,57% Option d'achat
CITADEL ADVISORS LLC $11 434 878 163 800 0,55% Option d'achat
AMERIPRISE FINANCIAL INC $11 050 085 158 288 0,53% Actions
Quinn Opportunity Partners LLC $10 686 236 153 076 0,51% Actions
GOLDMAN SACHS GROUP INC $10 011 801 143 415 0,48% Actions
Rhenman & Partners Asset Management AB $9 860 662 141 250 0,47% Actions
Qube Research & Technologies Ltd $9 111 671 130 521 0,44% Actions
LMR Partners LLP $9 075 300 130 000 0,44% Option de vente
Soleus Capital Management, L.P. $8 960 951 128 362 0,43% Actions
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. $8 570 364 122 767 0,41% Actions
Stonepine Capital Management, LLC $8 422 856 120 654 0,40% Actions
SummitTX Capital, L.P. $7 883 923 112 934 0,38% Actions
APEIRON CAPITAL Ltd $7 429 948 106 431 0,36% Actions
CITIGROUP INC $7 034 824 100 771 0,34% Actions
ING GROEP NV $6 981 000 100 000 0,33% Actions
LMR Partners LLP $6 981 000 100 000 0,33% Actions
Susquehanna Portfolio Strategies, LLC $6 685 704 95 770 0,32% Actions
Militia Capital Management LLC $6 282 900 90 000 0,30% Actions
ACT CAPITAL MANAGEMENT, LLC $6 234 033 89 300 0,30% Actions
Tetragon Partners GP Ltd $6 073 191 86 996 0,29% Actions
READYSTATE ASSET MANAGEMENT LP $5 941 529 85 110 0,28% Actions
Birchview Capital, LP $5 654 610 81 000 0,27% Actions
BlackRock, Inc. $5 444 412 77 989 0,26% Actions
GROUP ONE TRADING LLC $4 912 600 70 371 0,24% Actions
ALGERT GLOBAL LLC $4 686 345 67 130 0,22% Actions
Moody Aldrich Partners LLC $4 477 264 64 135 0,21% Actions
WOLVERINE TRADING, LLC $4 330 620 73 500 0,21% Option de vente
Swiss National Bank $4 300 296 61 600 0,21% Actions
F/m Investments LLC $4 229 439 60 585 0,20% Actions
BANK OF AMERICA CORP /DE/ $4 227 764 60 561 0,20% Actions
ExodusPoint Capital Management, LP $4 084 374 58 507 0,20% Actions
Trexquant Investment LP $3 956 831 56 680 0,19% Actions
K2 PRINCIPAL FUND, L.P. $3 522 962 50 465 0,17% Actions
WOLVERINE TRADING, LLC $3 403 101 57 758 0,16% Actions
RHUMBLINE ADVISERS $3 008 381 43 094 0,14% Actions
MORGAN STANLEY $2 943 050 42 158 0,14% Actions
Voleon Capital Management LP $2 850 901 40 838 0,14% Actions
Anson Funds Management LP $2 829 748 40 535 0,14% Actions
Atom Investors LP $2 828 631 40 519 0,14% Actions
WOLVERINE TRADING, LLC $2 792 808 47 400 0,13% Option d'achat
Burkehill Global Management, LP $2 792 400 40 000 0,13% Actions
NOMURA HOLDINGS INC $2 792 400 40 000 0,13% Option de vente
IRIDIAN ASSET MANAGEMENT LLC/CT $2 708 768 38 802 0,13% Actions
NOMURA HOLDINGS INC $2 698 645 38 657 0,13% Actions
Jefferies Financial Group Inc. $2 664 299 38 165 0,13% Actions
ALLIANCEBERNSTEIN L.P. $2 590 200 36 000 0,12% Actions
Connor, Clark & Lunn Investment Management Ltd. $2 575 780 36 897 0,12% Actions
ALPS ADVISORS INC $2 386 664 34 188 0,11% Actions
FRED ALGER MANAGEMENT, LLC $2 350 712 33 673 0,11% Actions
TUDOR INVESTMENT CORP ET AL $2 345 616 33 600 0,11% Option d'achat
Bank of New York Mellon Corp $2 306 522 33 040 0,11% Actions
Ghisallo Capital Management LLC $2 233 920 32 000 0,11% Actions
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $2 063 670 28 682 0,10% Actions
Blackstone Inc. $2 002 011 28 678 0,10% Actions
KVP Capital Advisors, LP $1 877 889 26 900 0,09% Actions
Ishara Investments LP $1 860 437 26 650 0,09% Actions
Erste Asset Management GmbH $1 830 920 28 000 0,09% Actions
Caption Management, LLC $1 822 041 26 100 0,09% Option de vente
WINTON GROUP Ltd $1 808 079 25 900 0,09% Actions
K2 PRINCIPAL FUND, L.P. $1 745 250 25 000 0,08% Option d'achat
Empowered Funds, LLC $1 636 416 23 441 0,08% Actions

Initiés de la société 40 initiés · 20 dirigeants · 18 administrateurs

Dirigeant Rôle Dernière activité Actions détenues Achats 12m Ventes 12m Net 12m
Howard W Robin President & CEO 24 juillet 2026 A 55 045 0 20 $-2 224 055
Jillian B. Thomsen Chief Financial Officer 16 février 2023 S 313 497 0 0 $0
Gil M Labrucherie SVP, COO & CFO 16 mai 2022 S 312 905 0 0 $0
Timothy Harkness SVP & Chief Financial Officer 23 août 2007 A 0 0 $0
Louis Drapeau Sr. VP Finance, CFO 14 mai 2007 A 6 000 0 0 $0
Milton J Harris President of Nektar AL 4 mars 2004 S 743 904 0 0 $0
John Nicholson SVP & Chief Operating Officer 16 août 2019 S 162 759 0 0 $0
Bharat M Chowrira Chief Operating Officer 1 février 2010 A 0 0 $0
Jonathan Zalevsky Chief R&D Officer 24 juillet 2026 A 9 756 0 12 $-1 052 364
Mark Andrew Wilson Chief Legal Officer 21 novembre 2025 A 21 585 0 2 $-52 171
John Northcott SVP & Chief Commercial Officer 16 mai 2022 S 223 210 0 0 $0
Stephen K Doberstein SVP & Chief Scientific Officer 5 septembre 2019 P 107 668 0 0 $0
Maninder Hora SVP Pharma Dev & Mfg Ops 16 mai 2019 S 94 694 0 0 $0
Ivan P. Gergel SVP & Chief Medical Officer 15 novembre 2017 A 56 553 0 0 $0
Robert Medve SVP & Chief Medical Officer 5 février 2014 A 0 0 $0
Rinko Ghosh Chief Business Officer 6 février 2013 A 9 753 0 0 $0
Randall W Moreadith SVP Drug Development 23 février 2009 A 0 0 $0
John Stuart Patton Chief Scientific Officer 14 novembre 2008 M 313 880 0 0 $0
Nevan C Elam SVP & Head of Pulmonary Bus 25 février 2008 A 1 400 0 0 $0
David Johnston SVP, Research & Development 14 mai 2007 D 6 600 0 0 $0
Diana Brainard Administrateur 30 septembre 2025 A 28 560 0 0 $0
Jeffrey Robert Ajer Administrateur 30 septembre 2025 A 34 153 0 0 $0
Robert Chess Administrateur 30 septembre 2025 A 255 273 0 0 $0
Scott R Greer Administrateur 30 septembre 2025 A 303 574 0 0 $0
Roy A Whitfield Administrateur 30 septembre 2025 A 216 250 0 0 $0
Myriam Curet Administrateur 19 septembre 2023 A 27 418 0 0 $0
Karin Eastham Administrateur 16 septembre 2022 A 23 233 0 0 $0
Lutz Lingnau Administrateur 22 septembre 2020 A 35 800 0 0 $0
Christopher A Kuebler Administrateur 27 septembre 2018 A 45 250 0 0 $0
Dennis L Winger Administrateur 21 août 2018 M 42 750 0 0 $0
Joseph J Krivulka Administrateur 19 septembre 2017 A 82 000 0 0 $0
Susan Wang Administrateur 20 novembre 2015 M 20 000 0 0 $0
BROWN MICHAEL A/CA Administrateur 15 septembre 2009 A 10 000 0 0 $0
Hoyoung Huh Administrateur 2 décembre 2008 A 0 0 $0
Irwin Lerner Administrateur 2 décembre 2008 A 10 000 0 0 $0
James B Glavin Administrateur 4 septembre 2003 A 0 0 $0
Masuoka K. Lorianne 8 février 2011 A 0 0 $0
Ajit Gill President & CEO 23 mars 2006 S 87 991 0 0 $0
Ajay Bansal 10 mars 2006 S 5 166 0 0 $0
Melvin Perelman 2 septembre 2004 A 0 0 $0

Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché

Activistes et détenteurs de 5%+ 1 participation

Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.

Déclarant Déposé Participation Statut Objectif Dépôt
Nektar Therapeutics ( 22 août 2005 Dépôt initial Fusions et acquisitions / vente SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Détention d'ETF Détenu par 28 ETFs

Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.

Fonds Poids Unités Au Source
LFSC · RBB Fund, Inc. 3,14% 50 876 NS 31 mai 2026 N-PORT
SPIT · RBB Fund, Inc. 3,11% 10 455 NS 30 avril 2026 N-PORT
PILL · Direxion Shares ETF Trust 1,55% 2 353 NS 30 avril 2026 N-PORT
BBC · ETFis Series Trust I 1,15% 5 045 NS 30 avril 2026 N-PORT
TMFX · RBB Fund, Inc. 0,09% 455 NS 31 mai 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0,04% 151 830 NS 31 mai 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0,03% 11 131 NS 30 avril 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0,00% 6 903 NS 31 mai 2026 N-PORT
TILT · FlexShares Trust 0,00% 770 NS 30 avril 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0,00% 18 540 NS 31 mai 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 15 juillet 2026 Quotidien
VTI · VANGUARD INDEX FUNDS 15 juillet 2026 Quotidien
VTWO · VANGUARD SCOTTSDALE FUNDS 15 juillet 2026 Quotidien
VTWV · VANGUARD SCOTTSDALE FUNDS 15 juillet 2026 Quotidien
VTWG · VANGUARD SCOTTSDALE FUNDS 15 juillet 2026 Quotidien
VTHR · VANGUARD SCOTTSDALE FUNDS 15 juillet 2026 Quotidien
ITOT · iShares Trust 22 juillet 2026 Quotidien
IWV · iShares Trust 18 août 2026 Quotidien
IWN · iShares Trust 17 août 2026 Quotidien
IWO · iShares Trust 18 août 2026 Quotidien
IWM · iShares Trust 18 août 2026 Quotidien
IHE · iShares Trust 18 août 2026 Quotidien
PRFZ · Invesco Exchange-Traded Fund Trust 4 août 2026 Quotidien
VHT · VANGUARD WORLD FUND 20 juillet 2026 Quotidien
ISCB · iShares Trust 20 juillet 2026 Quotidien
ISCV · iShares Trust 20 juillet 2026 Quotidien
WSML · iShares Trust 20 juillet 2026 Quotidien
QQQS · Invesco Exchange-Traded Fund Trust … 5 août 2026 Quotidien