OLMA Olema Pharmaceuticals, Inc. - Common Stock
$10,83
Prix · Aoû 18, 2026
Données fondamentales au Aoû 10, 2026
Fourchette 52 semaines
$5–$36
18% of range
Note des analystes
BUY
18 analysts
Objectif de cours
$40
+271% upside
P/E (TTM)
-5.8
ROE
-39.4%
Marge nette
—
OLMA Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
Prix
$10.82
Capitalisation Boursière
$881M
P/E (TTM)
-5.8
BPA (TTM)
$-1.87
Revenus (TTM)
—
Rendement div.
—
ROE
-39.4%
Dette/Capitaux propres
—
Fourchette 52 semaines
$5 – $36
OLMA Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Configure
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Revenus et bénéfice net
—
BPA
$-1.87
2019-12-31
→
2025-12-31
Flux de trésorerie libre
—
2021-12-31
→
2024-12-31
Marges
—
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Métrique
Tendance sur 5 ans
OLMA
Médiane des pairs
P/E (TTM)
-5.8
—
P/B
1.8
3.4
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Métrique
Tendance sur 5 ans
OLMA
Médiane des pairs
ROA
-33.0%
-31.3%
ROE
-39.4%
-38.1%
ROIC
-37.3%
—
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Métrique
Tendance sur 5 ans
OLMA
Médiane des pairs
Current Ratio (Ratio de liquidité)
10.0
10.9
Quick Ratio (Ratio de liquidité réduite)
9.8
—
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Métrique
Tendance sur 5 ans
OLMA
Médiane des pairs
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
Métrique
Tendance sur 5 ans
OLMA
Médiane des pairs
OLMA Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
ACHAT
18 analystes
- Achat fort 6 33,3%
- Achat 10 55,6%
- Conserver 2 11,1%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
10 analystes · 2026-08-17
Médiane
$40.00
← En dessous de tous les objectifs
$10.82
Bas
$20.00
Haut
$62.00
Objectif médian
$40.00
+269,5%
Objectif moyen
$40.20
+271,4%
Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
Surprise Moyenne
0.01%
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-0.61 | $-0.56 | -0.05% |
| 31 mars 2026 | $-0.52 | $-0.54 | 0.02% |
| 31 décembre 2025 | $-0.50 | $-0.54 | 0.04% |
| 30 septembre 2025 | $-0.49 | $-0.49 | 0.00% |
| 30 juin 2025 | $-0.51 | $-0.38 | -0.13% |
| 31 mars 2025 | $-0.36 | $-0.52 | 0.16% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| OLMA | $2.03B | -13.4 | — | — | -39.4% | — |
| CLYM | $191M | -4.5 | — | — | -34.6% | — |
| GERN | $845M | -10.2 | -60.2% | — | -34.4% | — |
| ANNX | $750M | -3.7 | — | — | -100.7% | — |
| SLDB | $445M | -2.8 | — | — | -79.5% | — |
| DSGN | $567M | -7.7 | — | — | -32.8% | — |
| CADL | $310M | -7.8 | — | — | -53.7% | — |
| FTH | — | — | — | — | — | — |
| IMMX | $277M | -5.9 | — | — | -59.8% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 15
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $158M | $125M | $86M | $82M | $51M | $14M | |
| SG&A Expense | $21M | $18M | $19M | $25M | $20M | $8M | |
| Operating Expenses | $179M | $142M | $105M | $107M | $71M | $22M | |
| Operating Income | $-179M | $-142M | $-105M | $-107M | $-71M | $-22M | |
| Interest Expense | · | · | · | · | · | $653.0K | |
| Interest Income | $16M | $13M | $8M | $2M | $442.0K | $60.0K | |
| Other Non-op | $23.0K | $102.0K | $-19.0K | $-27.0K | $-47.0K | · | |
| Pretax Income | $-162M | $-129M | · | · | · | · | |
| Income Tax | $3.0K | $2.0K | $2.0K | $1.0K | · | · | |
| Net Income | $-162M | $-129M | $-97M | $-105M | $-71M | $-22M | |
| EPS (Basic) | $-1.87 | $-2.20 | $-2.14 | $-2.62 | $-1.80 | $-3.42 | |
| EPS (Diluted) | $-1.87 | $-2.20 | $-2.14 | $-2.62 | $-1.80 | $-3.42 | |
| Shares (Basic) | 87,006,027 | 58,743,522 | 45,247,098 | 39,995,460 | 39,524,272 | 7,021,468 | |
| Shares (Diluted) | 87,006,027 | 58,743,522 | 45,247,098 | 39,995,460 | 39,524,272 | 7,021,468 | |
| EBITDA | $-178M | $-142M | $-105M | $-107M | $-71M | · |
Bilan 20
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $48M | $139M | $69M | $24M | $14M | $339M | |
| Short-term Investments | $457M | $295M | $193M | $181M | $273M | · | |
| Prepaid Expense | $10M | $4M | $5M | $4M | $3M | $4M | |
| Current Assets | $515M | $438M | $267M | $209M | $291M | $342M | |
| PP&E (Net) | $274.0K | $746.0K | $968.0K | $1M | $1M | $75.0K | |
| PP&E (Gross) | · | · | · | $2M | $2M | $137.0K | |
| Accum. Depreciation | · | · | · | $581.0K | $224.0K | $62.0K | |
| Other Non-current Assets | · | $15.0K | · | $3M | $540.0K | $510.0K | |
| Total Assets | $533M | $451M | $277M | $216M | $296M | $343M | |
| Accounts Payable | $9M | $4M | $3M | $374.0K | $23.0K | $719.0K | |
| Current Liabilities | $52M | $42M | $22M | $17M | $9M | $5M | |
| Capital Leases | $69.0K | $257.0K | $1M | $2M | $2M | · | |
| Total Liabilities | $55M | $42M | $23M | $18M | $11M | $5M | |
| Common Stock | $8.0K | $7.0K | $4.0K | $3.0K | $3.0K | $3.0K | |
| Paid-in Capital | $1.08B | $844M | $559M | $408M | $389M | $371M | |
| Retained Earnings | $-598M | $-435M | $-306M | $-209M | $-104M | $-33M | |
| AOCI | $621.0K | $143.0K | $347.0K | $-2M | $-149.0K | · | |
| Stockholders' Equity | $479M | $409M | $254M | $198M | $285M | $338M | |
| Liabilities + Equity | $533M | $451M | $277M | $216M | $296M | $343M | |
| Shares Outstanding | 81,376,449 | 74,312,608 | 54,992,784 | 40,287,097 | 39,797,263 | 39,308,238 |
Flux de trésorerie 9
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| D&A | $490.0K | $393.0K | $377.0K | $357.0K | $163.0K | $11.0K | |
| Stock-based Comp | $18M | $23M | $17M | $19M | $16M | $3M | |
| Other Non-cash | $-2M | $2M | $-5M | $4M | $4M | · | |
| Operating Cash Flow | $-147M | $-104M | $-84M | $-82M | $-51M | $-20M | |
| CapEx | · | $159.0K | · | $363.0K | $2M | $56.0K | |
| Investing Cash Flow | $-156M | $-94M | $-5M | $91M | $-275M | $-56.0K | |
| Financing Cash Flow | $211M | $269M | $133M | $476.0K | $1M | $358M | |
| Net Change in Cash | $-91M | $71M | $45M | $10M | $-325M | $338M | |
| Free Cash Flow | · | $-105M | · | $-82M | $-52M | · |
Rentabilité 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -33.0% | -35.6% | -39.2% | -41.0% | -22.3% | · | |
| ROE | -39.4% | -42.6% | -36.5% | -50.5% | -24.3% | · | |
| ROIC | -37.3% | · | · | · | · | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 10.0 | 10.5 | 12.3 | 12.6 | 32.2 | · | |
| Quick Ratio | 9.8 | 10.4 | 12.1 | 12.4 | 31.8 | · |
Valorisation (TTM) 8
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-162M | $-129M | $-97M | $-105M | $-71M | $-22M | |
| Market Cap | $2.03B | $433M | $772M | $99M | $373M | · | |
| P/E | -13.4 | -2.6 | -6.6 | -0.9 | -5.2 | -14.1 | |
| P/B | 4.3 | 1.1 | 3.0 | 0.5 | 1.3 | · | |
| P / Tangible Book | 4.3 | 1.1 | 3.0 | 0.5 | 1.3 | · | |
| P / Cash Flow | -13.9 | -4.2 | -9.2 | -1.2 | -7.3 | · | |
| P / FCF | · | -4.1 | · | -1.2 | -7.1 | · | |
| Earnings Yield | -7.5% | -37.7% | -15.2% | -106.9% | -19.2% | -7.1% |
Compte de résultat 12
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $58M | $49M | $43M | $40M | $44M | $31M | $32M | $33M | $29M | $30M | $26M | $19M | $18M | $23M | $22M | $18M | |
| SG&A Expense | $9M | $9M | $7M | $6M | $4M | $4M | $4M | $4M | $4M | $4M | $5M | $4M | $4M | $7M | $6M | $6M | |
| Operating Expenses | $67M | $58M | $50M | $46M | $48M | $35M | $37M | $38M | $34M | $34M | $30M | $23M | $22M | $30M | $27M | $23M | |
| Operating Income | $-67M | $-58M | $-50M | $-46M | $-48M | $-35M | $-37M | $-38M | $-34M | $-34M | $-30M | $-23M | $-22M | $-30M | $-27M | $-23M | |
| Interest Income | $5M | $5M | $4M | $4M | $4M | $5M | $3M | $3M | $3M | $3M | $4M | $2M | $2M | $1M | $973.0K | $622.0K | |
| Other Non-op | $-528.0K | $121.0K | $13.0K | $12.0K | $38.0K | $-40.0K | $-93.0K | $138.0K | $40.0K | $17.0K | $93.0K | $-79.0K | $-44.0K | $11.0K | $67.0K | $-120.0K | |
| Net Income | $-63M | $-53M | $-46M | $-42M | $-44M | $-30M | $-34M | $-35M | $-30M | $-31M | $-27M | $-22M | $-20M | $-28M | $-26M | $-23M | |
| EPS (Basic) | $-0.61 | $-0.52 | $-0.51 | $-0.49 | $-0.51 | $-0.36 | $-0.50 | $-0.60 | $-0.54 | $-0.56 | $-0.47 | $-0.48 | $-0.49 | $-0.70 | $-0.65 | $-0.57 | |
| EPS (Diluted) | $-0.61 | $-0.52 | $-0.51 | $-0.49 | $-0.51 | $-0.36 | $-0.50 | $-0.60 | $-0.54 | $-0.56 | $-0.47 | $-0.48 | $-0.49 | $-0.70 | $-0.65 | $-0.57 | |
| Shares (Basic) | 104,453,732 | 102,800,098 | -169,649,843 | 85,732,221 | 85,497,426 | 85,426,223 | -110,376,007 | 57,262,803 | 56,282,402 | 55,574,324 | -80,804,850 | 44,977,161 | 40,720,294 | 40,354,493 | -79,793,579 | 40,036,201 | |
| Shares (Diluted) | 104,453,732 | 102,800,098 | -169,649,843 | 85,732,221 | 85,497,426 | 85,426,223 | -110,376,007 | 57,262,803 | 56,282,402 | 55,574,324 | -80,804,850 | 44,977,161 | 40,720,294 | 40,354,493 | -79,793,579 | 40,036,201 | |
| EBITDA | $-67M | $-58M | · | $-46M | $-48M | $-35M | · | $-38M | $-34M | $-34M | · | $-23M | $-22M | $-30M | · | $-23M |
Bilan 20
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $49M | $53M | $48M | $35M | $52M | $51M | $139M | $36M | $17M | $34M | $69M | $117M | $35M | $41M | $24M | $27M | |
| Short-term Investments | $412M | $453M | $457M | $294M | $309M | $342M | $295M | $179M | $222M | $215M | $193M | $159M | $132M | $145M | $181M | $196M | |
| Prepaid Expense | $9M | $8M | $10M | $5M | $6M | $4M | $4M | $3M | $3M | $3M | $5M | $5M | $4M | $3M | $4M | $2M | |
| Current Assets | $470M | $513M | $515M | $334M | $368M | $397M | $438M | $218M | $242M | $252M | $267M | $282M | $172M | $189M | $209M | $225M | |
| PP&E (Net) | $382.0K | $356.0K | $274.0K | $486.0K | $560.0K | $653.0K | $746.0K | $849.0K | $945.0K | $1M | $968.0K | $1M | $1M | $1M | $1M | $1M | |
| PP&E (Gross) | · | · | · | · | · | · | · | · | · | · | · | $2M | $2M | $2M | · | $2M | |
| Accum. Depreciation | · | · | · | · | · | · | · | · | · | · | · | $698.0K | $744.0K | $681.0K | · | $484.0K | |
| Other Non-current Assets | · | · | · | · | $15.0K | $14.0K | $15.0K | $15.0K | $16.0K | · | · | · | · | $3M | · | $3M | |
| Total Assets | $487M | $531M | $533M | $352M | $382M | $410M | $451M | $230M | $255M | $264M | $277M | $293M | $178M | $196M | $216M | $232M | |
| Accounts Payable | $2M | $4M | $9M | $3M | $934.0K | $151.0K | $4M | $3M | $4M | $8M | $3M | $2M | $2M | $681.0K | $374.0K | $14.0K | |
| Current Liabilities | $53M | $47M | $52M | $42M | $33M | $26M | $42M | $31M | $27M | $26M | $22M | $16M | $15M | $19M | $17M | $13M | |
| Capital Leases | $0 | $0 | $69.0K | $310.0K | $602.0K | $123.0K | $257.0K | $562.0K | $859.0K | $1M | $1M | $2M | $1M | $1M | $2M | $2M | |
| Total Liabilities | $56M | $50M | $55M | $45M | $37M | $26M | $42M | $31M | $27M | $27M | $23M | $18M | $16M | $21M | $18M | $14M | |
| Common Stock | $8.0K | $8.0K | $8.0K | $7.0K | $7.0K | $7.0K | $7.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $3.0K | $3.0K | $3.0K | $3.0K | |
| Paid-in Capital | $1.15B | $1.13B | $1.08B | $858M | $854M | $849M | $844M | $600M | $594M | $573M | $559M | $554M | $419M | $413M | $408M | $403M | |
| Retained Earnings | $-714M | $-651M | $-598M | $-551M | $-509M | $-465M | $-435M | $-402M | $-367M | $-337M | $-306M | $-279M | $-257M | $-237M | $-209M | $-183M | |
| AOCI | $-947.0K | $-460.0K | $621.0K | $526.0K | $314.0K | $420.0K | $143.0K | $464.0K | $-118.0K | $-10.0K | $347.0K | $-241.0K | $-518.0K | $-978.0K | $-2M | $-3M | |
| Stockholders' Equity | $431M | $480M | $479M | $307M | $345M | $383M | $409M | $199M | $227M | $236M | $254M | $275M | $162M | $175M | $198M | $218M | |
| Liabilities + Equity | $487M | $531M | $533M | $352M | $382M | $410M | $451M | $230M | $255M | $264M | $277M | $293M | $178M | $196M | $216M | $232M | |
| Shares Outstanding | 87,452,166 | 87,332,971 | 81,376,449 | 68,652,730 | 68,627,886 | 68,333,065 | 74,312,608 | 57,288,319 | 57,246,411 | 55,867,863 | 54,992,784 | 54,601,516 | 41,122,482 | 40,438,320 | 40,287,097 | 40,084,568 |
Flux de trésorerie 9
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $102.0K | $119.0K | $187.0K | $43.0K | $132.0K | $128.0K | $116.0K | $95.0K | $94.0K | $88.0K | $88.0K | $90.0K | $99.0K | $100.0K | $97.0K | $91.0K | |
| Stock-based Comp | $13M | $10M | $4M | $4M | $5M | $4M | $6M | $6M | $6M | $5M | $4M | $4M | $4M | $5M | $5M | $4M | |
| Other Non-cash | · | $-3M | · | · | · | $-18M | · | · | · | $2M | · | · | · | $3M | · | · | |
| Operating Cash Flow | $-46M | $-46M | $-38M | $-35M | $-30M | $-44M | $-26M | $-27M | $-28M | $-23M | $-18M | $-23M | $-22M | $-20M | $-20M | $-18M | |
| CapEx | · | · | · | $0 | · | · | $0 | $0 | $6.0K | $153.0K | · | · | · | · | $173.0K | $139.0K | |
| Investing Cash Flow | $41M | $5M | $-162M | $17M | $34M | $-45M | $-114M | $46M | $-5M | $-20M | $-31M | $-25M | $14M | $37M | $16M | $20M | |
| Financing Cash Flow | $1M | $46M | $214M | $41.0K | $-3M | $222.0K | $244M | $92.0K | $16M | $9M | $523.0K | $131M | $2M | $220.0K | $273.0K | $106.0K | |
| Net Change in Cash | $-4M | $4M | $13M | $-17M | $2M | $-89M | $104M | $19M | $-17M | $-35M | $-49M | $82M | $-6M | $17M | $-3M | $2M | |
| Free Cash Flow | · | · | · | · | · | · | · | · | · | $-24M | · | · | · | · | · | · |
Rentabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -14.5% | -11.3% | · | -14.5% | -13.8% | -9.0% | · | -13.2% | -14.1% | -13.5% | · | -8.2% | -9.4% | -12.0% | · | -8.4% | |
| ROE | -16.3% | -12.3% | · | -16.7% | -15.3% | -9.8% | · | -14.6% | -15.6% | -15.1% | · | -8.7% | -10.1% | -12.9% | · | -8.8% |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 8.9 | 10.9 | · | 8.0 | 11.1 | 15.2 | · | 7.1 | 9.1 | 9.6 | · | 17.7 | 11.6 | 9.8 | · | 17.9 | |
| Quick Ratio | 8.7 | 10.7 | · | 7.9 | 10.9 | 15.1 | · | 7.0 | 9.0 | 9.5 | · | 17.3 | 11.3 | 9.6 | · | 17.7 |
Valorisation (TTM) 8
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-202M | $-169M | · | $-151M | $-139M | $-126M | · | $-117M | $-103M | $-101M | · | $-93M | $-104M | $-107M | · | $-96M | |
| Market Cap | $1.09B | $1.30B | · | $672M | $292M | $257M | · | $684M | $619M | $632M | · | $674M | $371M | $140M | · | $111M | |
| P/E | -5.9 | -7.9 | · | -5.0 | -2.1 | -1.8 | · | -5.5 | -5.2 | -5.1 | · | -5.5 | -3.5 | -1.3 | · | -1.1 | |
| P/B | 2.5 | 2.7 | · | 2.2 | 0.8 | 0.7 | · | 3.4 | 2.7 | 2.7 | · | 2.5 | 2.3 | 0.8 | · | 0.5 | |
| P / Tangible Book | 2.5 | 2.7 | · | 2.2 | 0.8 | 0.7 | · | 3.4 | 2.7 | 2.7 | · | 2.5 | 2.3 | 0.8 | · | 0.5 | |
| P / Cash Flow | · | -28.3 | · | · | · | -5.8 | · | · | · | -26.9 | · | · | · | -6.9 | · | · | |
| P / FCF | · | · | · | · | · | · | · | · | · | -26.7 | · | · | · | · | · | · | |
| Earnings Yield | -17.0% | -12.6% | · | -20.0% | -47.2% | -54.8% | · | -18.3% | -19.1% | -19.7% | · | -18.1% | -28.6% | -77.0% | · | -87.7% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Résultat net | $-162M | $-129M | $-97M | $-105M | $-71M |
| BPA dilué | $-1.87 | $-2.20 | $-2.14 | $-2.62 | $-1.80 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 10.0 | 10.5 | 12.3 | 12.6 | 32.2 |
| Ratio de liquidité réduite | 9.8 | 10.4 | 12.1 | 12.4 | 31.8 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | — | $-105M | — | $-82M | $-52M |
Dernières actualités Actualités récentes mentionnant cette entreprise
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Détenteurs institutionnels (13F) 201 déclarants · $1.1B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
Activité institutionnelle — Q2 2026 vs trimestre précédent
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 32 (-20 vs T. préc.) | 37 (-10 vs T. préc.) | 69 (-1 vs T. préc.) | 61 (+6 vs T. préc.) | +2.5M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| FMR LLC | $109 938 906 | 8 788 082 | 10,35% | Actions |
| Paradigm Biocapital Advisors LP | $108 468 906 | 8 670 576 | 10,21% | Actions |
| Bain Capital Life Sciences Investors, LLC | $88 636 465 | 7 085 249 | 8,34% | Actions |
| VANGUARD GROUP INC | $81 312 975 | 3 252 519 | 7,65% | Actions |
| BVF INC/IL | $66 251 621 | 5 295 893 | 6,23% | Actions |
| Siren, L.L.C. | $60 760 432 | 4 856 949 | 5,72% | Actions |
| STATE STREET CORP | $53 993 886 | 4 316 058 | 5,08% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $41 798 625 | 3 341 217 | 3,93% | Actions |
| Logos Global Management LP | $40 143 026 | 3 208 875 | 3,78% | Actions |
| FRANKLIN RESOURCES INC | $29 375 482 | 2 348 160 | 2,76% | Actions |
| Cormorant Asset Management, LP | $26 896 500 | 2 150 000 | 2,53% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $20 806 857 | 1 663 218 | 1,96% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $19 640 235 | 1 569 659 | 1,85% | Actions |
| Deep Track Capital, LP | $18 765 000 | 1 500 000 | 1,77% | Actions |
| GOLDMAN SACHS GROUP INC | $17 828 551 | 1 425 144 | 1,68% | Actions |
| LIGHTSPEED MANAGEMENT COMPANY, L.L.C. | $16 954 790 | 1 355 299 | 1,60% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $16 685 012 | 1 333 734 | 1,57% | Actions |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | $15 012 000 | 1 200 000 | 1,41% | Actions |
| TWO SIGMA INVESTMENTS, LP | $14 154 239 | 1 131 434 | 1,33% | Actions |
| Point72 Asset Management, L.P. | $13 397 572 | 1 070 949 | 1,26% | Actions |
| Defilade Capital Management, L.P. | $11 568 723 | 924 758 | 1,09% | Actions |
| AMERIPRISE FINANCIAL INC | $10 346 508 | 827 059 | 0,97% | Actions |
| Woodline Partners LP | $9 395 385 | 751 030 | 0,88% | Actions |
| Candriam S.C.A. | $9 387 633 | 751 133 | 0,88% | Actions |
| Vivo Capital, LLC | $8 404 756 | 671 843 | 0,79% | Actions |
| Qube Research & Technologies Ltd | $8 298 121 | 663 319 | 0,78% | Actions |
| Squarepoint Ops LLC | $7 699 530 | 615 470 | 0,72% | Actions |
| READYSTATE ASSET MANAGEMENT LP | $7 428 801 | 593 829 | 0,70% | Actions |
| Jones Hill Capital LP | $7 182 817 | 574 166 | 0,68% | Actions |
| Hudson Bay Capital Management LP | $7 085 664 | 566 400 | 0,67% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $6 484 458 | 518 342 | 0,61% | Actions |
| CITADEL ADVISORS LLC | $5 710 252 | 456 455 | 0,54% | Actions |
| Vestal Point Capital, LP | $5 236 073 | 418 551 | 0,49% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $5 192 338 | 415 055 | 0,49% | Actions |
| Ikarian Capital, LLC | $4 794 845 | 383 281 | 0,45% | Actions |
| SEB Asset Management AB | $4 246 649 | 339 461 | 0,40% | Actions |
| Fisher Asset Management, LLC | $3 712 015 | 296 724 | 0,35% | Actions |
| BANK OF AMERICA CORP /DE/ | $3 148 342 | 251 666 | 0,30% | Actions |
| Rock Springs Capital Management LP | $2 942 077 | 235 178 | 0,28% | Actions |
| Pier Capital, LLC | $2 760 944 | 220 699 | 0,26% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $2 589 432 | 206 989 | 0,24% | Actions |
| Ikarian Capital, LLC | $2 502 000 | 200 000 | 0,24% | Option d'achat |
| Birchview Capital, LP | $2 489 490 | 199 000 | 0,23% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2 280 573 | 182 300 | 0,21% | Option de vente |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | $2 024 566 | 161 836 | 0,19% | Actions |
| HighVista Strategies LLC | $2 003 689 | 160 167 | 0,19% | Actions |
| Susquehanna Portfolio Strategies, LLC | $1 847 339 | 147 669 | 0,17% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $1 784 051 | 142 610 | 0,17% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 665 769 | 133 155 | 0,16% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 563 150 | 124 952 | 0,15% | Actions |
| ALLIANCEBERNSTEIN L.P. | $1 530 810 | 102 670 | 0,14% | Actions |
| CITIGROUP INC | $1 514 173 | 121 037 | 0,14% | Actions |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $1 393 142 | 114 192 | 0,13% | Actions |
| TD Asset Management Inc | $1 328 737 | 106 214 | 0,13% | Actions |
| Swiss National Bank | $1 313 550 | 105 000 | 0,12% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 297 287 | 103 700 | 0,12% | Option d'achat |
| Integral Health Asset Management, LLC | $1 251 000 | 100 000 | 0,12% | Actions |
| RHUMBLINE ADVISERS | $1 245 110 | 99 530 | 0,12% | Actions |
| Trexquant Investment LP | $1 156 074 | 92 412 | 0,11% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1 125 775 | 89 990 | 0,11% | Actions |
| XTX Topco Ltd | $1 119 958 | 89 525 | 0,11% | Actions |
| TEMA ETFS LLC | $1 112 625 | 44 505 | 0,10% | Actions |
| ALPS ADVISORS INC | $1 108 999 | 88 649 | 0,10% | Actions |
| Bank of New York Mellon Corp | $1 071 482 | 85 650 | 0,10% | Actions |
| BlackRock, Inc. | $1 070 956 | 85 608 | 0,10% | Actions |
| VICTORY CAPITAL MANAGEMENT INC | $1 026 195 | 82 030 | 0,10% | Actions |
| ALGERT GLOBAL LLC | $1 012 409 | 80 928 | 0,10% | Actions |
| FEDERATED HERMES, INC. | $966 598 | 77 266 | 0,09% | Actions |
| AQR CAPITAL MANAGEMENT LLC | $960 893 | 76 810 | 0,09% | Actions |
| Rafferty Asset Management, LLC | $944 780 | 75 522 | 0,09% | Actions |
| ExodusPoint Capital Management, LP | $877 476 | 70 142 | 0,08% | Actions |
| WELLS FARGO & COMPANY/MN | $833 691 | 66 642 | 0,08% | Actions |
| Connor, Clark & Lunn Investment Management Ltd. | $827 699 | 66 163 | 0,08% | Actions |
| NOMURA HOLDINGS INC | $825 660 | 66 000 | 0,08% | Option de vente |
| LPL Financial LLC | $737 352 | 58 941 | 0,07% | Actions |
| Quantinno Capital Management LP | $699 046 | 55 879 | 0,07% | Actions |
| CITADEL ADVISORS LLC | $691 803 | 55 300 | 0,07% | Option d'achat |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | $689 564 | 55 121 | 0,06% | Actions |
| Swedbank AB | $689 301 | 55 100 | 0,06% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $688 050 | 55 000 | 0,06% | Option d'achat |
| Engineers Gate Manager LP | $669 961 | 53 554 | 0,06% | Actions |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $626 000 | 50 000 | 0,06% | Actions |
| PORTLAND INVESTMENT COUNSEL INC. | $625 500 | 50 000 | 0,06% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $582 668 | 39 079 | 0,05% | Actions |
| MetLife Investment Management, LLC | $581 715 | 46 500 | 0,05% | Actions |
| Headlands Technologies LLC | $515 937 | 41 242 | 0,05% | Actions |
| NOMURA HOLDINGS INC | $505 404 | 40 400 | 0,05% | Option d'achat |
| PRUDENTIAL FINANCIAL INC | $494 896 | 39 560 | 0,05% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $482 811 | 38 594 | 0,05% | Actions |
| PROFUND ADVISORS LLC | $479 871 | 38 359 | 0,05% | Actions |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $469 901 | 37 562 | 0,04% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $451 586 | 36 098 | 0,04% | Actions |
| JANUS HENDERSON GROUP PLC | $450 716 | 30 219 | 0,04% | Actions |
| Aristotle Atlantic Partners, LLC | $448 609 | 35 860 | 0,04% | Actions |
| NOMURA HOLDINGS INC | $423 539 | 33 856 | 0,04% | Actions |
| Virtus Investment Advisers, LLC | $414 707 | 33 150 | 0,04% | Actions |
| JANE STREET GROUP, LLC | $401 571 | 32 100 | 0,04% | Option d'achat |
| Seven Fleet Capital Management LP | $393 765 | 31 476 | 0,04% | Actions |
| Invesco Ltd. | $389 224 | 31 113 | 0,04% | Actions |
| Caption Management, LLC | $375 300 | 30 000 | 0,04% | Option d'achat |
Initiés de la société 19 initiés · 7 dirigeants · 12 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Sean Bohen | President and CEO | 1 février 2023 A | 51 649 | 0 | 0 | $0 |
| Naseem Zojwalla | Chief Medical Officer | 1 février 2023 A | — | 0 | 0 | $0 |
| David C. Myles | Chief Development Officer | 1 février 2023 A | 154 846 | 0 | 0 | $0 |
| Kinney Horn | Chief Business Officer | 1 février 2023 A | — | 0 | 0 | $0 |
| Shane William Charles Kovacs | Ch. Operating & Financial Off. | 1 février 2023 A | 358 680 | 0 | 0 | $0 |
| John B Moriarty | EVP, Ch. Legal Officer & Sec. | 1 février 2023 A | — | 0 | 0 | $0 |
| Peter J. Kushner | Chief Scientific Officer | 23 novembre 2020 C | 1 431 672 | 0 | 0 | $0 |
| Cyrus Harmon | Administrateur | 24 juillet 2026 S | 702 770 | 0 | 2 | $-291 125 |
| Prakash Raman | Administrateur | 18 juin 2026 A | — | 0 | 0 | $0 |
| Hrustanovic Gorjan | Administrateur | 18 juin 2026 A | — | 0 | 0 | $0 |
| Yi Larson | Administrateur | 18 juin 2026 A | — | 0 | 0 | $0 |
| Graham Walmsley | Administrateur | 18 juin 2026 A | 700 761 | 0 | 0 | $0 |
| Sandra Horning | Administrateur | 18 juin 2026 A | — | 0 | 0 | $0 |
| Scott J. Garland | Administrateur | 18 juin 2026 A | — | 0 | 0 | $0 |
| Ian T Clark | Administrateur | 18 juin 2026 A | 0 | 0 | 3 | $-7 873 109 |
| Cynthia M Butitta | Administrateur | 18 juin 2026 A | 83 876 | 0 | 0 | $0 |
| Andrew Rappaport | Administrateur | 18 juin 2026 A | 0 | 0 | 0 | $0 |
| Frank Mccormick | Administrateur | 23 novembre 2020 C | 84 260 | 0 | 0 | $0 |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | Détenteur de 10% | 23 novembre 2020 C | 1 725 406 | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 2 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| Logos Global Management LP, Logos Global Management GP LLC, Arsani William, Graham Walmsley, Logos Opportunities GP LLC, Logos GP LLC ×4 dépôts | 13 mai 2025 | 4,70% | Amendement | Investissement passif | SEC |
| BIOTECHNOLOGY VALUE FUND, L.P., BVF I GP LLC, BIOTECHNOLOGY VALUE FUND II, L.P., BVF II GP LLC, BIOTECHNOLOGY VALUE TRADING FUND OS, L.P., BVF PARTNERS OS LTD., BVF GP HOLDINGS LLC, BVF PARTNERS L.P., BVF INC., MARK N. LAMPERT, GORJAN HRUSTANOVIC ×4 dépôts | 4 décembre 2024 | — | Dépôt initial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 45 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 0,66% | 81 077 NS | 31 mai 2026 | N-PORT |
| CANC · Tema ETF Trust | 0,60% | 79 759 NS | 31 mai 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,39% | 141 558 NS | 30 avril 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 0,36% | 11 250 NS | 31 mai 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,32% | 8 351 NS | 30 avril 2026 | N-PORT |
| IWC · iShares Trust | 0,21% | 266 015 SH | 8 août 2026 | Quotidien |
| VFMO · VANGUARD WELLINGTON FUND | 0,11% | 180 516 SH | 8 août 2026 | Quotidien |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,07% | 4 753 SH | 8 août 2026 | Quotidien |
| IBB · iShares Trust | 0,06% | 515 376 SH | 8 août 2026 | Quotidien |
| BIB · ProShares Trust | 0,05% | 2 962 NS | 31 mai 2026 | N-PORT |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,05% | 56 779 SH | 8 août 2026 | Quotidien |
| IWN · iShares Trust | 0,05% | 606 631 SH | 8 août 2026 | Quotidien |
| FFSM · FIDELITY COVINGTON TRUST | 0,04% | 40 123 NS | 30 avril 2026 | N-PORT |
| RSSL · Global X Funds | 0,03% | 30 271 NS | 30 avril 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,03% | 451 269 SH | 8 août 2026 | Quotidien |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,03% | 71 008 SH | 8 août 2026 | Quotidien |
| IWM · iShares Trust | 0,03% | 2 004 959 SH | 8 août 2026 | Quotidien |
| DFAS · Dimensional ETF Trust | 0,03% | 284 227 NS | 30 avril 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,03% | 18 801 NS | 31 mai 2026 | N-PORT |
| ITWO · ProShares Trust | 0,02% | 3 287 NS | 31 mai 2026 | N-PORT |
| ISCV · iShares Trust | 0,01% | 8 558 SH | 8 août 2026 | Quotidien |
| SCHA · SCHWAB STRATEGIC TRUST | 0,01% | 247 403 NS | 31 mai 2026 | N-PORT |
| UWM · ProShares Trust | 0,01% | 2 571 NS | 31 mai 2026 | N-PORT |
| ISCB · iShares Trust | 0,01% | 2 951 SH | 8 août 2026 | Quotidien |
| ISCG · iShares Trust | 0,01% | 8 602 SH | 8 août 2026 | Quotidien |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 652 061 SH | 8 août 2026 | Quotidien |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,01% | 14 261 SH | 8 août 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | 0,01% | 157 394 SH | 8 août 2026 | Quotidien |
| URTY · ProShares Trust | 0,01% | 2 602 NS | 31 mai 2026 | N-PORT |
| IWO · iShares Trust | 0,01% | 121 187 SH | 8 août 2026 | Quotidien |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 17 308 NS | 30 avril 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 2 374 NS | 31 mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 65 NS | 31 mai 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 1 110 NS | 30 avril 2026 | N-PORT |
| WSML · iShares Trust | 0,00% | 2 299 SH | 8 août 2026 | Quotidien |
| DCOR · Dimensional ETF Trust | 0,00% | 6 974 NS | 30 avril 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,00% | 23 513 NS | 31 mai 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 21 603 NS | 30 avril 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 75 925 NS | 30 avril 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 16 063 NS | 30 avril 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 79 886 SH | 8 août 2026 | Quotidien |
| IWV · iShares Trust | 0,00% | 17 373 SH | 8 août 2026 | Quotidien |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 28 000 NS | 31 mai 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 2 611 290 SH | 8 août 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 7 103 SH | 8 août 2026 | Quotidien |