| FMR LLC |
$298,894,493 |
7,172,894 |
13.99% |
주식
|
| TRV GP V, LLC |
$261,709,477 |
6,280,525 |
12.25% |
주식
|
| ARCH Venture Management, LLC |
$155,376,512 |
3,728,738 |
7.27% |
주식
|
| Capital International Investors |
$121,757,990 |
2,921,958 |
5.70% |
주식
|
| GOLDMAN SACHS GROUP INC |
$121,278,410 |
2,910,449 |
5.68% |
주식
|
| BlackRock, Inc. |
$112,500,083 |
2,699,786 |
5.27% |
주식
|
| Cormorant Asset Management, LP |
$110,738,900 |
2,657,521 |
5.18% |
주식
|
| Sofinnova Investments, Inc. |
$79,356,681 |
1,904,408 |
3.71% |
주식
|
| JOHNSON & JOHNSON |
$74,360,823 |
1,784,517 |
3.48% |
주식
|
| Polar Capital Holdings Plc |
$67,026,778 |
1,608,514 |
3.14% |
주식
|
| BAKER BROS. ADVISORS LP |
$64,467,240 |
1,547,090 |
3.02% |
주식
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$56,109,155 |
1,346,512 |
2.63% |
주식
|
| VANGUARD GROUP INC |
$55,150,747 |
1,817,757 |
2.58% |
주식
|
| TRV GP VI, LLC |
$40,387,314 |
969,218 |
1.89% |
주식
|
| STATE STREET CORP |
$34,115,729 |
818,712 |
1.60% |
주식
|
| GEODE CAPITAL MANAGEMENT, LLC |
$33,068,458 |
793,453 |
1.55% |
주식
|
| PERCEPTIVE ADVISORS LLC |
$32,225,161 |
773,342 |
1.51% |
주식
|
| Vestal Point Capital, LP |
$30,419,100 |
730,000 |
1.42% |
주식
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$28,751,317 |
918,866 |
1.35% |
주식
|
| Siren, L.L.C. |
$26,730,013 |
641,469 |
1.25% |
주식
|
| Capital World Investors |
$22,987,547 |
551,657 |
1.08% |
주식
|
| ALLIANCEBERNSTEIN L.P. |
$21,695,985 |
693,384 |
1.02% |
주식
|
| DIMENSIONAL FUND ADVISORS LP |
$15,087,064 |
362,114 |
0.71% |
주식
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$14,998,866 |
359,944 |
0.70% |
주식
|
| Candriam S.C.A. |
$14,472,638 |
347,650 |
0.68% |
주식
|
| Sio Capital Management, LLC |
$12,820,067 |
307,657 |
0.60% |
주식
|
| MORGAN STANLEY |
$12,401,492 |
297,612 |
0.58% |
주식
|
| NORTHERN TRUST CORP |
$11,555,299 |
277,305 |
0.54% |
주식
|
| KENNEDY CAPITAL MANAGEMENT LLC |
$10,450,628 |
250,795 |
0.49% |
주식
|
| Burkehill Global Management, LP |
$10,417,500 |
250,000 |
0.49% |
주식
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$10,284,781 |
246,815 |
0.48% |
주식
|
| ALGERT GLOBAL LLC |
$9,326,663 |
223,822 |
0.44% |
주식
|
| Invesco Ltd. |
$8,968,884 |
215,236 |
0.42% |
주식
|
| D. E. Shaw & Co., Inc. |
$8,952,008 |
214,831 |
0.42% |
주식
|
| VANGUARD FIDUCIARY TRUST CO |
$8,681,236 |
208,333 |
0.41% |
주식
|
| Ensign Peak Advisors, Inc |
$6,898,302 |
165,546 |
0.32% |
주식
|
| MILLENNIUM MANAGEMENT LLC |
$6,455,016 |
154,908 |
0.30% |
주식
|
| UBS Group AG |
$6,299,420 |
151,174 |
0.29% |
주식
|
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
$6,250,500 |
150,000 |
0.29% |
주식
|
| Artia Global Partners LP |
$5,771,628 |
138,508 |
0.27% |
주식
|
| Swedbank AB |
$4,892,058 |
117,400 |
0.23% |
주식
|
| Nuveen, LLC |
$4,307,053 |
103,361 |
0.20% |
주식
|
| Walleye Capital LLC |
$4,257,132 |
102,163 |
0.20% |
주식
|
| Woodline Partners LP |
$4,064,367 |
97,537 |
0.19% |
주식
|
| TD Asset Management Inc |
$3,828,556 |
91,878 |
0.18% |
주식
|
| WELLINGTON MANAGEMENT GROUP LLP |
$3,624,790 |
86,988 |
0.17% |
주식
|
| PRUDENTIAL FINANCIAL INC |
$3,620,498 |
86,885 |
0.17% |
주식
|
| CITADEL ADVISORS LLC |
$3,435,358 |
82,442 |
0.16% |
주식
|
| Bank of New York Mellon Corp |
$3,426,191 |
82,222 |
0.16% |
주식
|
| ORBIMED ADVISORS LLC |
$3,192,589 |
76,616 |
0.15% |
주식
|
| BANK OF AMERICA CORP /DE/ |
$3,170,087 |
76,076 |
0.15% |
주식
|
| DAFNA Capital Management LLC |
$3,125,250 |
75,000 |
0.15% |
주식
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$2,903,649 |
69,682 |
0.14% |
주식
|
| STEMPOINT CAPITAL LP |
$2,774,472 |
66,582 |
0.13% |
주식
|
| AMERICAN CENTURY COMPANIES INC |
$2,740,386 |
65,764 |
0.13% |
주식
|
| XTX Topco Ltd |
$2,560,246 |
61,441 |
0.12% |
주식
|
| VOYA INVESTMENT MANAGEMENT LLC |
$2,439,237 |
58,537 |
0.11% |
주식
|
| Allspring Global Investments Holdings, LLC |
$2,394,692 |
57,468 |
0.11% |
주식
|
| JANE STREET GROUP, LLC |
$2,321,228 |
55,705 |
0.11% |
주식
|
| Russell Investments Group, Ltd. |
$2,310,936 |
55,458 |
0.11% |
주식
|
| Swiss National Bank |
$2,300,184 |
55,200 |
0.11% |
주식
|
| Trexquant Investment LP |
$2,247,555 |
53,937 |
0.11% |
주식
|
| ALPS ADVISORS INC |
$2,010,286 |
48,243 |
0.09% |
주식
|
| Susquehanna Portfolio Strategies, LLC |
$1,665,883 |
39,978 |
0.08% |
주식
|
| RHUMBLINE ADVISERS |
$1,550,030 |
37,198 |
0.07% |
주식
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$1,354,233 |
32,499 |
0.06% |
주식
|
| DEUTSCHE BANK AG\ |
$1,342,274 |
32,212 |
0.06% |
주식
|
| WELLS FARGO & COMPANY/MN |
$1,340,566 |
32,171 |
0.06% |
주식
|
| Integrated Quantitative Investments LLC |
$1,266,185 |
30,386 |
0.06% |
주식
|
| AQR CAPITAL MANAGEMENT LLC |
$1,102,338 |
26,454 |
0.05% |
주식
|
| TWO SIGMA INVESTMENTS, LP |
$1,019,665 |
24,470 |
0.05% |
주식
|
| CITIGROUP INC |
$1,015,623 |
24,373 |
0.05% |
주식
|
| Ellsworth Advisors, LLC |
$979,842 |
24,539 |
0.05% |
주식
|
| Creative Planning |
$954,993 |
22,918 |
0.04% |
주식
|
| Legal & General Group Plc |
$939,867 |
22,555 |
0.04% |
주식
|
| STATE OF WISCONSIN INVESTMENT BOARD |
$920,949 |
22,101 |
0.04% |
주식
|
| BNP PARIBAS FINANCIAL MARKETS |
$919,032 |
22,055 |
0.04% |
주식
|
| Engineers Gate Manager LP |
$888,154 |
21,314 |
0.04% |
주식
|
| Y-Intercept (Hong Kong) Ltd |
$799,606 |
19,189 |
0.04% |
주식
|
| VANGUARD ASSET MANAGEMENT, Ltd |
$772,228 |
18,532 |
0.04% |
주식
|
| MetLife Investment Management, LLC |
$750,435 |
18,009 |
0.04% |
주식
|
| Vanguard Global Advisers, LLC |
$718,391 |
17,240 |
0.03% |
주식
|
| SEI INVESTMENTS CO |
$678,971 |
16,294 |
0.03% |
주식
|
| JPMORGAN CHASE & CO |
$669,021 |
16,564 |
0.03% |
주식
|
| BARCLAYS PLC |
$624,800 |
14,994 |
0.03% |
주식
|
| AMERIPRISE FINANCIAL INC |
$612,382 |
14,696 |
0.03% |
주식
|
| OPTIMIZE FINANCIAL INC. |
$608,632 |
14,606 |
0.03% |
주식
|
| Zurcher Kantonalbank (Zurich Cantonalbank) |
$594,048 |
14,256 |
0.03% |
주식
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$587,880 |
14,108 |
0.03% |
주식
|
| PSP Research LLC |
$583,380 |
14,000 |
0.03% |
주식
|
| VARCOV Co. |
$537,335 |
12,895 |
0.03% |
주식
|
| China Universal Asset Management Co., Ltd. |
$450,536 |
10,812 |
0.02% |
주식
|
| Allianz Asset Management GmbH |
$445,869 |
10,700 |
0.02% |
주식
|
| JANUS HENDERSON GROUP PLC |
$432,768 |
13,800 |
0.02% |
주식
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$429,201 |
10,300 |
0.02% |
주식
|
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM |
$424,034 |
10,176 |
0.02% |
주식
|
| CATALYST PRIVATE WEALTH, LLC |
$416,700 |
10,000 |
0.02% |
주식
|
| STIFEL FINANCIAL CORP |
$407,243 |
9,773 |
0.02% |
주식
|
| CLEAR WAVE WEALTH MANAGEMENT LLC |
$395,865 |
9,500 |
0.02% |
주식
|
| Police & Firemen's Retirement System of New Jersey |
$376,447 |
9,034 |
0.02% |
주식
|
| State of New Jersey Common Pension Fund D |
$370,321 |
8,887 |
0.02% |
주식
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$362,529 |
8,700 |
0.02% |
콜 옵션
|
| Virtus Investment Advisers, LLC |
$355,070 |
8,521 |
0.02% |
주식
|
| INTECH INVESTMENT MANAGEMENT LLC |
$348,820 |
8,371 |
0.02% |
주식
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$343,986 |
8,255 |
0.02% |
주식
|
| ARIZONA STATE RETIREMENT SYSTEM |
$316,025 |
7,584 |
0.01% |
주식
|
| Vanguard Investments Australia, Ltd. |
$302,483 |
7,259 |
0.01% |
주식
|
| AlphaCentric Advisors LLC |
$272,147 |
6,531 |
0.01% |
주식
|
| Quadrature Capital Ltd |
$264,980 |
6,359 |
0.01% |
주식
|
| PROFUND ADVISORS LLC |
$264,938 |
6,358 |
0.01% |
주식
|
| KLP KAPITALFORVALTNING AS |
$245,853 |
5,900 |
0.01% |
주식
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$241,686 |
5,800 |
0.01% |
풋 옵션
|
| ProShare Advisors LLC |
$232,519 |
5,580 |
0.01% |
주식
|
| Pictet Asset Management Holding SA |
$216,601 |
5,198 |
0.01% |
주식
|
| JANE STREET GROUP, LLC |
$208,350 |
5,000 |
0.01% |
풋 옵션
|
| Sandia Investment Management LP |
$182,040 |
6,000 |
0.01% |
주식
|
| Tower Research Capital LLC (TRC) |
$124,010 |
2,976 |
0.01% |
주식
|
| Ameritas Investment Partners, Inc. |
$115,843 |
2,780 |
0.01% |
주식
|
| MEEDER ASSET MANAGEMENT INC |
$115,593 |
2,774 |
0.01% |
주식
|
| AlphaQuest LLC |
$113,896 |
3,754 |
0.01% |
주식
|
| STRS OHIO |
$108,342 |
2,600 |
0.01% |
주식
|
| Mirae Asset Global Investments Co., Ltd. |
$89,132 |
2,139 |
0.00% |
주식
|
| Aquatic Capital Management LLC |
$88,007 |
2,112 |
0.00% |
주식
|
| NISA INVESTMENT ADVISORS, LLC |
$79,923 |
1,918 |
0.00% |
주식
|
| State of Wyoming |
$65,005 |
1,560 |
0.00% |
주식
|
| ROYAL BANK OF CANADA |
$47,000 |
1,147 |
0.00% |
주식
|
| CWM, LLC |
$46,153 |
1,475 |
0.00% |
주식
|
| Tidemark, LLC |
$45,337 |
1,088 |
0.00% |
주식
|
| GF FUND MANAGEMENT CO. LTD. |
$42,128 |
1,011 |
0.00% |
주식
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$32,814 |
787,446 |
0.00% |
주식
|
| LOS ANGELES CAPITAL MANAGEMENT LLC |
$32,128 |
771 |
0.00% |
주식
|
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. |
$20,710 |
497 |
0.00% |
주식
|
| GAMMA Investing LLC |
$17,001 |
408 |
0.00% |
주식
|
| T. Rowe Price Investment Management, Inc. |
$16,385 |
393,200 |
0.00% |
주식
|
| Caitong International Asset Management Co., Ltd |
$15,668 |
376 |
0.00% |
주식
|
| FEDERATED HERMES, INC. |
$10,001 |
240 |
0.00% |
주식
|
| Stone House Investment Management, LLC |
$8,792 |
211 |
0.00% |
주식
|
| SIGNATUREFD, LLC |
$8,542 |
205 |
0.00% |
주식
|
| MassMutual Private Wealth & Trust, FSB |
$6,792 |
163 |
0.00% |
주식
|
| EverSource Wealth Advisors, LLC |
$6,125 |
147 |
0.00% |
주식
|
| Sterling Capital Management LLC |
$5,875 |
141 |
0.00% |
주식
|
| Larson Financial Group LLC |
$5,459 |
131 |
0.00% |
주식
|
| OSAIC HOLDINGS, INC. |
$5,167 |
124 |
0.00% |
주식
|
| TD Waterhouse Canada Inc. |
$4,845 |
123 |
0.00% |
주식
|
| Aster Capital Management (DIFC) Ltd |
$4,500 |
108 |
0.00% |
주식
|
| Arax Advisory Partners |
$2,251 |
54 |
0.00% |
주식
|
| Optiver Holding B.V. |
$2,250 |
54 |
0.00% |
주식
|
| SBI Securities Co., Ltd. |
$2,209 |
53 |
0.00% |
주식
|
| Cornerstone Financial Management LLC |
$2,042 |
49 |
0.00% |
주식
|
| PNC Financial Services Group, Inc. |
$2,000 |
48 |
0.00% |
주식
|
| True Wealth Design, LLC |
$1,709 |
41 |
0.00% |
주식
|
| Essential Partners LLC |
$1,667 |
40 |
0.00% |
주식
|
| Bare Financial Services, Inc |
$1,625 |
39 |
0.00% |
주식
|
| Versant Capital Management, Inc |
$1,125 |
27 |
0.00% |
주식
|
| Versant Capital Management, Inc |
$907 |
27 |
0.00% |
주식
|
| Silver Grove Financial Group, Inc. |
$875 |
21 |
0.00% |
주식
|
| ROTHSCHILD INVESTMENT LLC |
$833 |
20 |
0.00% |
주식
|
| US BANCORP \DE\ |
$583 |
14 |
0.00% |
주식
|
| Sunbelt Securities, Inc. |
$344 |
11 |
0.00% |
주식
|
| Allworth Financial LP |
$292 |
7 |
0.00% |
주식
|
| NATIONAL BANK OF CANADA /FI/ |
$291 |
7 |
0.00% |
주식
|
| Ameritas Advisory Services, LLC |
$208 |
5 |
0.00% |
주식
|
| Lindbrook Capital, LLC |
$150 |
15 |
0.00% |
주식
|
| IFP Advisors, Inc |
$125 |
3 |
0.00% |
주식
|
| Global Retirement Partners, LLC |
$83 |
2 |
0.00% |
주식
|
| KBC Group NV |
$40 |
962 |
0.00% |
주식
|
| ACADIAN ASSET MANAGEMENT LLC |
$39 |
957 |
0.00% |
주식
|
| Covestor Ltd |
$1 |
17 |
0.00% |
주식
|