ABUS Arbutus Biopharma Corporation - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$4.74
Price · Aug 18, 2026
Fundamentals as of Aug 12, 2026

About Arbutus Biopharma Corporation - Common Stock Company overview from Wikipedia

Arbutus Biopharma Corporation is a publicly traded Canadian biopharmaceutical company with an expertise in liposomal drug delivery and RNA interference, and is developing drugs for hepatitis B infection.

Read more

Arbutus Biopharma Corporation is a publicly traded Canadian (NASDAQ: ABUS) biopharmaceutical company with an expertise in liposomal drug delivery and RNA interference, and is developing drugs for hepatitis B infection.

It is headquartered in Warminster, Pennsylvania. The company was formerly known as Tekmira, which was spun out of Inex Pharmaceuticals in 2007.

History

Tekmira, as the company was formerly called, was formed as a wholly owned subsidiary of Inex Pharmaceuticals in 2005 after that company began collapsing after its regulatory and partnering strategy failed in 2004. Tekmira was fully spun out in 2007 and Tekmira absorbed the assets of Inex, which had been founded in 1992.

Inex had been developing liposomal formulations of off-patent cancer drugs, and licensed them to Talon Pharmaceuticals in 2005; Talon was acquired by Spectrum Pharmaceuticals in 2013, and three former Inex/Tekmira products reached the market and began generating royalties for Tekmira: Marqibo (liposomal vincristine), Alocrest (liposomal vinorelbine) and Brakiva (liposomal topotecan).

Inex had also acquired licenses to intellectual property, as well as staff and manufacturing facilities, concerning RNAi technology from Lynx Therapeutics in 1998; this set of technologies became the focus for Tekmira and it initially sought to develop liposomally encapsulated RNAi drugs for a broad range of indications.

Tekmira also worked on providing liposomal delivery technology to other companies. In 2007 it signed a license agreement with Alnylam Pharmaceuticals so that Alnylam could use it to deliver its own RNAi drugs; that deal was expanded into a manufacturing agreement in 2009.

Most of those products not focused on viral diseases faltered, and Tekmira had only $6.3 million in cash when it filed suit against Alnylam in 2011 for breaching its contract and stealing trade secrets. The suit was settled in 2012, with Alnylam agreeing to pay Tekmira $65 million in termination fees, and the companies negotiated a new license agreement with lower milestones and royalties, which covers Alnylam's product patisiran.

Tekmira caught the world's attention and its stock rose dramatically during the 2013 West African Ebola virus epidemic due to its drug candidate for Ebola fever, TKM-Ebola. Tekmira was developing it under a $140 million US Department of Defense contract. While its stock was trading high in January 2015, it acquired OnCore BioPharma, a company focused on hepatitis B.

On December 19, 2014, Tekmira announced the appointment of former Bill & Melinda Gates Foundation CFO Richard Henriques to the company's board of directors. The company simultaneously announced the forthcoming departure of Ian MacLachlan as Executive Vice President and Chief Technical Officer.

Development of TKM-Ebola was terminated in mid June 2015 during a Phase II trial, for lack of efficacy.

The next month, Tekmira changed its name to Arbutus Biopharma and said that it would focus on drugs to treat hepatitis B.

In March 2017 Arbutus signed another license for its liposome delivery technology, this time with Alexion Pharmaceuticals, for delivery of an mRNA drug candidate. This license was terminated in July 2017, when Alexion discontinued preclinical programs outside its core complement franchise.

In 2019, Arbutus began a phase 1 clinical study using AB-506 to treat chronic hepatitis B. The company released preliminary data in July and stopped the trial in October after two patients developed acute hepatitis. Now AB-729 is paving the way for Arbutus, as they recently received the FDA go ahead to pursue phase 2 trials, after having their data voted best in ILC, 2021; after abandoning development of previous investigational agents. AB-836, Arbutus's next generation capsid inhibitor, has shown potential against mutants in its phase 1 trials.

In July 2019, Arbutus Biopharma announced the sale of part of its royalty interest on future global net sales of ONPATTRO, an RNA interference therapeutic currently sold by Alnylam Pharmaceuticals, to OMERS for $20 million.

COVID-19

On March 10, 2023, U.S. District Judge Mitchell Goldberg rejected a bid by Moderna to dismiss some of the patent infringement claims brought against the company by Arbutus and its partner, Genevant Sciences.

Moderna settled their lawsuit and will pay Arbutus $950 million upfront and an additional $1.3 billion contingent upon a favorable resolution of Moderna’s Section 1498 appeal.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

ABUS Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$4.74
Market Cap
$934M
P/E (TTM)
-28.5
EPS (TTM)
$-0.17
Revenue (TTM)
$14M
Div Yield
ROE
-42.0%
Debt/Equity
52W Range
$3 – $5

ABUS Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $14M
10-point trend, +844.5%
2016-12-31 2025-12-31
EPS $-0.17
9-point trend, +97.7%
2016-12-31 2025-12-31
Free Cash Flow $-40M
9-point trend, +35.9%
2016-12-31 2025-12-31
Margins -237.9%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
ABUS
Peer Median
P/E (TTM)
5-point trend, -503.7%
-28.5
6.7
P/S (TTM)
5-point trend, +28.1%
66.3
39.8
P/B
5-point trend, +263.3%
12.2
4.8
Price / FCF
5-point trend, -183.1%
-23.6

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
ABUS
Peer Median
Operating Margin
5-point trend, +59.5%
-271.0%
Net Profit Margin
5-point trend, +65.7%
-237.9%
-220.1%
ROA
5-point trend, +33.7%
-29.6%
-35.0%
ROE
5-point trend, +17.5%
-42.0%
-43.2%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
ABUS
Peer Median
Current Ratio
5-point trend, +9.8%
15.7
9.7
Quick Ratio
5-point trend, +11.1%
15.5

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
ABUS
Peer Median
Revenue YoY
5-point trend, +28.2%
128.2%
Revenue CAGR 3Y
5-point trend, +28.2%
-28.8%
Revenue CAGR 5Y
5-point trend, +28.2%
15.3%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
ABUS
Peer Median
EPS (Diluted)
5-point trend, +79.5%
$-0.17

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
ABUS
Peer Median

ABUS Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 8 analysts
  • Strong Buy 3 37.5%
  • Buy 4 50.0%
  • Hold 1 12.5%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

1 analysts · 2026-08-17
Median target $5.53 +16.6%
Mean target $5.53 +16.6%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.01%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.05 $-0.03 -0.02%
Dec. 31, 2025 $-0.02 $-0.04 0.02%
Sept. 30, 2025 $-0.04 $-0.03 -0.01%
June 30, 2025 $0.01 $-0.05 0.06%
March 31, 2025 $-0.13 $-0.11 -0.02%
Dec. 31, 2024 $-0.07 $-0.08 0.01%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ABUS $926M -28.3 128.2% -237.9% -42.0%
XENE $3.59B -10.3 -4612.1% -56.9%
AUPH $2.11B 7.7 20.4% 101.5% 62.7%
ZYME $1.97B -24.4 38.9% -76.6% -26.9%
ACOG $141M -5.5 -202.2% -43.8%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 16
Annual Income Statement data for ABUS
Metric Trend 20252024202320222021202020192018201720162015
Revenue 11-point trend, -39.5% $14M $6M $18M $39M $11M $7M $6M $6M $11M $1M $23M
R&D Expense 11-point trend, -51.0% $25M $54M $74M $84M $66M $49M $58M $58M $63M $61M $52M
SG&A Expense 11-point trend, -39.9% $16M $22M $22M $18M $17M $15M $18M $16M $16M $39M $26M
Operating Expenses 11-point trend, -58.9% $52M $82M $96M $104M $85M $65M $150M $96M $122M $493M $127M
Operating Income 11-point trend, +63.3% $-38M $-76M $-78M $-65M $-74M $-58M $-144M $-90M $-111M $-492M $-104M
Interest Expense 9-point trend, +459000.00 · · $459.0K $2M $3M $4M $2M $226.0K $261.0K $0 $0
Interest Income 11-point trend, +503.6% $4M $7M $6M $2M $127.0K $741.0K $2M $3M $2M $1M $674.0K
Other Non-op 11-point trend, -81.4% $5M $6M $5M $444.0K $-3M $-6M $-22M $28M $2M $2M $25M
Pretax Income 6-point trend, +19.2% · · · · · $-64M $-166M $-61M $-109M $-489M $-79M
Income Tax 11-point trend, +100.0% $0 $0 $0 $4M $0 $0 $-13M $-4M $-24M $-105M $-16M
Net Income 11-point trend, +46.6% $-34M $-70M $-73M $-69M $-76M $-64M $-154M $-57M $-84M $-384M $-63M
EPS (Basic) 10-point trend, +87.7% $-0.17 $-0.38 $-0.44 $-0.46 $-0.83 $-1.00 · $-1.21 $-1.56 $-7.24 $-1.38
EPS (Diluted) 10-point trend, +87.7% $-0.17 $-0.38 $-0.44 $-0.46 $-0.83 $-1.00 · $-1.21 $-1.56 $-7.24 $-1.38
Shares (Basic) 10-point trend, +321.4% 191,599,600 185,608,874 165,960,379 150,939,337 106,242,452 75,835,378 · 55,304,083 54,723,272 53,074,401 45,462,324
Shares (Diluted) 10-point trend, +321.4% 191,599,600 185,608,874 165,960,379 150,939,337 106,242,452 75,835,378 · 55,304,083 54,723,272 53,074,401 45,462,324
EBITDA 9-point trend, +92.2% $-38M $-76M $-78M $-65M $-74M $-58M · $-90M $-111M $-492M ·
Balance Sheet 25
Annual Balance Sheet data for ABUS
Metric Trend 20252024202320222021202020192018201720162015
Cash & Equivalents 11-point trend, -89.2% $18M $36M $26M $31M $109M $52M $32M $37M $54M $23M $167M
Short-term Investments 11-point trend, +405.8% $73M $86M $100M $116M $46M $71M $59M $88M $72M $107M $15M
Receivables 11-point trend, +43.6% $1M $2M $2M $1M $899.0K $1M $1M $1M $402.0K $273.0K $1M
Prepaid Expense 11-point trend, +28.6% $2M $2M $4M $3M $4M $3M $2M $3M $2M $1M $1M
Current Assets 11-point trend, -48.6% $94M $127M $132M $151M $161M $128M $94M $129M $129M $133M $184M
PP&E (Net) 11-point trend, -99.0% $32.0K $3M $5M $5M $6M $7M $9M $10M $12M $7M $3M
PP&E (Gross) 11-point trend, -98.1% $245.0K $16M $17M $16M $15M $15M $14M $17M $25M $18M $13M
Accum. Depreciation 11-point trend, -97.8% $213.0K $13M $12M $11M $9M $8M $6M $7M $13M $11M $10M
Goodwill 5-point trend, -100.0% · · · · · · $0 $22M $24M $24M $163M
Intangibles 5-point trend, -100.0% · · · · · · $0 $44M $59M $99M $353M
Other Non-current Assets 8-point trend, +130000.00 $130.0K $34.0K $0 $103.0K $61.0K $44.0K $293.0K $0 · · ·
Total Assets 11-point trend, -86.7% $95M $132M $144M $195M $204M $137M $106M $228M $237M $276M $712M
Accounts Payable 11-point trend, -38.2% $5M $8M $10M $16M $11M $9M $7M $9M $11M $10M $9M
Current Liabilities 11-point trend, -43.2% $6M $16M $22M $33M $11M $10M $8M $11M $15M $11M $11M
Capital Leases 8-point trend, +199000.00 $199.0K $806.0K $1M $2M $2M $3M $3M $0 · · ·
Deferred Tax 5-point trend, -100.0% · · · · · · $0 $13M $17M $41M $146M
Total Liabilities 11-point trend, -89.0% $18M $34M $38M $59M $35M $35M $33M $28M $55M $73M $165M
Long-term Debt Flat — no change across 5 periods $0 $0 $0 $0 $0 · · · · · ·
Common Stock 11-point trend, +70.4% $1.42B $1.41B $1.35B $1.32B $1.29B $986M $899M $879M $876M $867M $834M
Paid-in Capital 11-point trend, +175.8% $83M $82M $81M $72M $65M $61M $55M $48M $43M $37M $30M
Retained Earnings 11-point trend, -416.9% $-1.38B $-1.35B $-1.28B $-1.20B $-1.13B $-1.05B $-970M $-805M $-738M $-653M $-267M
AOCI 11-point trend, +3.4% $-48M $-48M $-48M $-50M $-48M $-48M $-48M $-48M $-48M $-48M $-50M
Stockholders' Equity 11-point trend, -86.0% $77M $97M $106M $137M $169M $102M $73M $200M $182M $203M $548M
Liabilities + Equity 11-point trend, -86.7% $95M $132M $144M $195M $204M $137M $106M $228M $237M $276M $712M
Shares Outstanding 11-point trend, +252.8% 192,531,225 189,963,492 169,867,414 157,455,363 144,987,736 89,678,722 64,780,314 55,518,800 55,060,650 54,841,494 54,570,691
Cash Flow 14
Annual Cash Flow data for ABUS
Metric Trend 20252024202320222021202020192018201720162015
Stock-based Comp 9-point trend, -54.0% $7M $9M $9M $7M $6M $6M $7M $6M $15M · ·
Deferred Tax 6-point trend, +100.0% · · · · · $0 $-13M $-4M $-24M $-105M $-16M
Restructuring 8-point trend, +12939000.00 $13M $4M $0 · $0 $64.0K $156.0K $5M $0 · ·
Operating Cash Flow 11-point trend, +29.7% $-40M $-65M $-86M $-35M $-68M $-51M $-71M $-68M $-49M $-58M $-56M
CapEx 11-point trend, -100.0% $0 $182.0K $1M $512.0K $809.0K $229.0K $589.0K $1M $7M $4M $2M
Investing Cash Flow 11-point trend, +102.8% $16M $23M $51M $-75M $-13M $-15M $28M $-4M $28M $-99M $8M
Debt Issued 3-point trend, +0.00 · · · · · · · · $0 $12M $0
Net Debt Issued 2-point trend, -100.0% · · · · · · · · $0 $12M ·
Stock Issued 7-point trend, -5.3% · · · · $135M $86M $19M $0 $0 $0 $142M
Net Stock Activity 4-point trend, +134665000.00 · · · · $135M $86M · · $0 $0 ·
Financing Cash Flow 11-point trend, -96.0% $6M $52M $31M $32M $137M $87M $37M $56M $49M $13M $144M
Net Change in Cash 11-point trend, -119.4% $-18M $10M $-4M $-79M $57M $20M $-5M $-17M $31M $-143M $95M
Free Cash Flow 9-point trend, +35.9% $-40M $-65M $-87M $-36M $-68M $-52M · $-69M $-56M $-62M ·
Levered FCF 3-point trend, +0.8% · · · · · $-56M · $-69M $-56M · ·
Profitability 7
Annual Profitability data for ABUS
Metric Trend 20252024202320222021202020192018201720162015
Operating Margin 9-point trend, +99.2% -271.0% -1236.7% -430.5% -167.8% -669.1% -836.1% · -1510.2% -1036.7% -32973.8% ·
Net Margin 9-point trend, +99.1% -237.9% -1133.0% -401.6% -178.0% -693.9% -922.0% · -959.8% -788.9% -25765.5% ·
Pretax Margin 4-point trend, +97.2% · · · · · -922.0% · -1031.8% -1016.2% -32807.9% ·
EBITDA Margin 9-point trend, +99.2% -271.0% -1236.7% -430.5% -167.8% -669.1% -836.1% · -1510.2% -1036.7% -32973.8% ·
ROA 9-point trend, +61.9% -29.6% -50.6% -42.9% -34.7% -44.6% -52.5% · -24.5% -32.9% -77.8% ·
ROE 9-point trend, +59.0% -42.0% -68.5% -64.6% -49.2% -50.9% -64.0% · -27.5% -43.8% -102.4% ·
ROIC 4-point trend, +70.2% · · · · · -56.7% · -41.7% -47.2% -190.2% ·
Liquidity & Solvency 3
Annual Liquidity & Solvency data for ABUS
Metric Trend 20252024202320222021202020192018201720162015
Current Ratio 9-point trend, +25.6% 15.7 8.2 5.9 4.6 14.3 13.4 · 11.5 8.8 12.5 ·
Quick Ratio 9-point trend, +25.2% 15.5 8.0 5.7 4.5 13.9 13.1 · 11.2 8.7 12.4 ·
Interest Coverage 6-point trend, +60.0% · · -170.2 -37.9 -25.7 -14.4 · -397.3 -425.0 · ·
Efficiency 2
Annual Efficiency data for ABUS
Metric Trend 20252024202320222021202020192018201720162015
Asset Turnover 9-point trend, +4046.7% 0.1 0.0 0.1 0.2 0.1 0.1 · 0.0 0.0 0.0 ·
Receivables Turnover 9-point trend, +213.8% 7.3 2.9 11.6 34.7 9.9 5.5 · 6.5 31.7 2.3 ·
Per Share 5
Annual Per Share data for ABUS
Metric Trend 20252024202320222021202020192018201720162015
Book Value / Share 9-point trend, -89.3% $0.40 $0.51 $0.62 $0.87 $1.17 $1.14 · $3.61 $3.31 $3.70 ·
Revenue / Share 8-point trend, +161.6% $0.07 $0.03 $0.11 $0.26 $0.10 · · $0.11 $0.20 $0.03 ·
Cash Flow / Share 8-point trend, +81.0% $-0.21 $-0.35 $-0.52 $-0.23 $-0.64 · · $-1.23 $-0.89 $-1.09 ·
Cash / Share 9-point trend, -78.1% $0.09 $0.19 $0.15 $0.20 $0.75 $0.58 · $0.67 $0.99 $0.43 ·
EPS (TTM) 11-point trend, +87.7% $-0.17 $-0.38 $-0.44 $-0.46 $-0.83 $-1.00 $-1.32 $-1.21 $-1.56 $-7.24 $-1.38
Growth Rates 3
Annual Growth Rates data for ABUS
Metric Trend 20252024202320222021202020192018201720162015
Revenue YoY 5-point trend, +117.6% 128.2% -66.0% -53.5% 255.1% 58.9% · · · · · ·
Revenue CAGR 3Y 3-point trend, -175.9% -28.8% -17.5% 37.9% · · · · · · · ·
Revenue CAGR 5Y 15.3% · · · · · · · · · ·
Valuation (TTM) 10
Annual Valuation (TTM) data for ABUS
Metric Trend 20252024202320222021202020192018201720162015
Revenue TTM 11-point trend, -39.5% $14M $6M $18M $39M $11M $7M $6M $6M $11M $1M $23M
Net Income TTM 11-point trend, +46.6% $-34M $-70M $-73M $-69M $-76M $-64M $-154M $-57M $-84M $-384M $-63M
Market Cap 9-point trend, +589.2% $926M $621M $425M $367M $564M $318M · $213M $278M $134M ·
P/E 11-point trend, -777.4% -28.3 -8.6 -5.7 -5.1 -4.7 -3.5 -2.1 -3.2 -3.2 -0.3 -3.2
P/S 9-point trend, -27.0% 65.8 100.7 23.4 9.4 51.3 46.0 · 35.8 26.0 90.1 ·
P/B 9-point trend, +1727.1% 12.1 6.4 4.0 2.7 3.3 3.1 · 1.1 1.5 0.7 ·
P / Tangible Book 6-point trend, +287.3% 12.1 6.4 4.0 2.7 3.3 3.1 · · · · ·
P / Cash Flow 9-point trend, -906.5% -23.4 -9.6 -4.9 -10.4 -8.4 -6.2 · -3.1 -5.7 -2.3 ·
P / FCF 9-point trend, -976.0% -23.4 -9.6 -4.9 -10.2 -8.3 -6.2 · -3.1 -5.0 -2.2 ·
Earnings Yield 11-point trend, +88.6% -3.5% -11.6% -17.6% -19.7% -21.3% -28.2% -47.5% -31.6% -30.9% -295.5% -31.0%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $14M$6M$18M$39M$11M
Operating Margin % -271.0%-1236.7%-430.5%-167.8%-669.1%
Net Income $-34M$-70M$-73M$-69M$-76M
Diluted EPS $-0.17$-0.38$-0.44$-0.46$-0.83
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 15.78.25.94.614.3
Quick Ratio 15.58.05.74.513.9
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-40M$-65M$-87M$-36M$-68M

Latest News Recent headlines mentioning this company

My Metrics Your personal watchlist — selected rows from Full Fundamentals

📊

Pick the metrics that matter to you — click the ➕ next to any row in Full Fundamentals above.

Your selection is saved and follows you across all tickers.

Institutional owners (13F) 191 filers · $496.0M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
41 (+15 vs prior Q) 22 (-8 vs prior Q) 55 (+10 vs prior Q) 44 (-8 vs prior Q) +14.8M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Two Seas Capital LP $91,658,798 19,095,583 18.48% Shares
Whitefort Capital Management, LP $75,812,453 15,794,261 15.28% Shares
VANGUARD GROUP INC $38,412,670 7,986,002 7.74% Shares
STATE STREET CORP $37,772,059 7,869,179 7.62% Shares
Rubric Capital Management LP $36,158,098 7,532,937 7.29% Shares
VANGUARD CAPITAL MANAGEMENT LLC $33,651,259 7,010,679 6.78% Shares
GEODE CAPITAL MANAGEMENT, LLC $16,983,987 3,537,471 3.42% Shares
BlackBarn Capital Partners LP $12,000,000 2,500,000 2.42% Shares
Woodline Partners LP $10,952,909 2,281,856 2.21% Shares
GOLDMAN SACHS GROUP INC $8,545,829 1,780,381 1.72% Shares
Jefferies Financial Group Inc. $8,216,026 1,711,672 1.66% Shares
NOMURA HOLDINGS INC $7,857,989 1,637,081 1.58% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $7,398,998 1,541,458 1.49% Shares
BANK OF AMERICA CORP /DE/ $7,169,851 1,493,719 1.45% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $6,869,846 1,431,218 1.38% Shares
OSAIC HOLDINGS, INC. $6,469,756 1,347,866 1.30% Shares
ADAR1 Capital Management, LLC $6,087,106 1,268,147 1.23% Shares
Deltroit Asset Management (UK) LLP $5,760,000 1,200,000 1.16% Shares
VANGUARD FIDUCIARY TRUST CO $5,449,738 1,135,362 1.10% Shares
CITIGROUP INC $4,175,784 869,955 0.84% Shares
BANK OF MONTREAL /CAN/ $3,734,102 777,938 0.75% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $3,123,360 650,700 0.63% Shares
MACKENZIE FINANCIAL CORP $2,946,269 613,806 0.59% Shares
LOS ANGELES CAPITAL MANAGEMENT LLC $2,889,638 602,008 0.58% Shares
Western Standard LLC $2,605,378 542,787 0.53% Shares
Rangeley Capital, LLC $2,400,000 500,000 0.48% Shares
Man Group plc $2,272,642 473,467 0.46% Shares
Corbin Capital Partners, L.P. $2,231,732 682,487 0.45% Shares
CenterBook Partners LP $2,136,725 445,151 0.43% Shares
Freestone Capital Holdings, LLC $2,124,000 442,500 0.43% Shares
CITADEL ADVISORS LLC $1,942,541 404,696 0.39% Shares
KENNEDY CAPITAL MANAGEMENT LLC $1,849,430 385,298 0.37% Shares
Swiss National Bank $1,375,200 286,500 0.28% Shares
Ledgewood Wealth Advisors, LLC $1,336,493 278,436 0.27% Shares
FMR LLC $1,277,232 266,090 0.26% Shares
Susquehanna Portfolio Strategies, LLC $1,265,688 263,685 0.26% Shares
Carrera Capital Advisors $1,234,402 257,167 0.25% Shares
Quinn Opportunity Partners LLC $1,225,027 255,214 0.25% Shares
D. E. Shaw & Co., Inc. $1,209,614 252,003 0.24% Shares
STATE OF WISCONSIN INVESTMENT BOARD $1,161,682 242,017 0.23% Shares
Campbell & CO Investment Adviser LLC $1,106,563 230,534 0.22% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,080,475 225,099 0.22% Shares
Squarepoint Ops LLC $999,096 208,145 0.20% Shares
MARTINGALE ASSET MANAGEMENT L P $926,880 193,100 0.19% Shares
RHUMBLINE ADVISERS $909,224 189,423 0.18% Shares
STRS OHIO $810,720 168,900 0.16% Shares
Bank of New York Mellon Corp $801,067 166,889 0.16% Shares
Caption Management, LLC $720,000 150,000 0.15% Call option
Caption Management, LLC $720,000 150,000 0.15% Put option
Hudson Bay Capital Management LP $720,000 150,000 0.15% Shares
Wealth Management Associates, Inc. $710,376 147,995 0.14% Shares
WELLINGTON MANAGEMENT GROUP LLP $701,467 146,139 0.14% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $643,433 142,985 0.13% Shares
ALLIANCEBERNSTEIN L.P. $631,080 140,240 0.13% Shares
Connor, Clark & Lunn Investment Management Ltd. $619,685 129,101 0.12% Shares
BlackRock, Inc. $567,398 118,208 0.11% Shares
Front Row Advisors LLC $516,035 110,500 0.10% Shares
BARCLAYS PLC $499,320 104,025 0.10% Shares
Rafferty Asset Management, LLC $490,416 102,170 0.10% Shares
MetLife Investment Management, LLC $452,885 94,351 0.09% Shares
VANGUARD ASSET MANAGEMENT, Ltd $429,994 89,582 0.09% Shares
TWO SIGMA INVESTMENTS, LP $407,933 84,986 0.08% Shares
JBF Capital, Inc. $385,349 80,281 0.08% Shares
Integrated Quantitative Investments LLC $383,698 79,937 0.08% Shares
Virtus Investment Advisers, LLC $368,674 76,807 0.07% Shares
XTX Topco Ltd $365,808 76,210 0.07% Shares
AMERICAN CENTURY COMPANIES INC $317,832 66,215 0.06% Shares
Invesco Ltd. $305,616 63,670 0.06% Shares
Rockefeller Capital Management L.P. $302,400 63,000 0.06% Shares
Creative Planning $298,133 62,111 0.06% Shares
JANUS HENDERSON GROUP PLC $273,746 60,900 0.06% Shares
Quantinno Capital Management LP $273,413 56,961 0.06% Shares
Zurcher Kantonalbank (Zurich Cantonalbank) $265,118 55,233 0.05% Shares
Vanguard Global Advisers, LLC $264,730 55,152 0.05% Shares
Mitsubishi UFJ Asset Management Co., Ltd. $255,936 53,320 0.05% Shares
Jump Financial, LLC $255,178 53,162 0.05% Shares
PROFUND ADVISORS LLC $254,482 53,017 0.05% Shares
WOLVERINE TRADING, LLC $248,868 55,800 0.05% Call option
Police & Firemen's Retirement System of New Jersey $248,203 51,709 0.05% Shares
Exome Asset Management LLC $240,797 50,166 0.05% Shares
Magnetar Financial LLC $225,922 47,067 0.05% Shares
State of New Jersey Common Pension Fund D $221,602 46,167 0.04% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $212,664 44,305 0.04% Shares
ALLSTATE CORP $212,285 44,226 0.04% Shares
Quadrature Capital Ltd $201,619 42,004 0.04% Shares
Universal- Beteiligungs- und Servicegesellschaft mbH $189,475 39,474 0.04% Shares
ARIZONA STATE RETIREMENT SYSTEM $189,110 39,398 0.04% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $175,680 36,600 0.04% Call option
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $171,936 35,820 0.03% Shares
NEW YORK STATE COMMON RETIREMENT FUND $169,286 35,268 0.03% Shares
INTECH INVESTMENT MANAGEMENT LLC $167,208 34,835 0.03% Shares
Mitsubishi UFJ Trust & Banking Corp $152,102 31,688 0.03% Shares
VOYA INVESTMENT MANAGEMENT LLC $151,070 31,473 0.03% Shares
China Universal Asset Management Co., Ltd. $150,902 31,438 0.03% Shares
Vanguard Investments Australia, Ltd. $150,182 31,288 0.03% Shares
KLP KAPITALFORVALTNING AS $148,320 30,900 0.03% Shares
Premier Path Wealth Partners, LLC $144,000 30,000 0.03% Shares
BNP PARIBAS FINANCIAL MARKETS $139,675 29,099 0.03% Shares
SHERBROOKE PARK ADVISERS LLC $134,627 27,989 0.03% Shares
EntryPoint Capital, LLC $134,112 27,940 0.03% Shares

Company insiders 25 insiders · 13 officers · 11 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
William H. Collier President and CEO June 24, 2019 A 0 0 $0
Mark J. Murray President and CEO March 1, 2019 A 341,396 0 0 $0
David C Hastings Chief Financial Officer March 1, 2019 A 0 0 $0
Bruce Cousins EVP & Chief Financial Officer March 24, 2017 A 0 0 $0
Gaston Picchio Chief Development Officer March 1, 2019 A 0 0 $0
Elizabeth Howard Executive VP & General Counsel March 1, 2019 A 0 0 $0
Michael J. Mcelhaugh Chief Business Officer March 1, 2019 A 0 0 $0
Michael J. Sofia Chief Scientific Officer March 1, 2019 A 1,503,403 0 0 $0
Koert Vandenenden Chief Accounting Officer Dec. 11, 2018 A 0 0 $0
William T. Symonds Chief Development Officer April 16, 2018 A 0 0 $0
Peter Lutwyche Chief Technology Officer March 24, 2017 A 0 0 $0
Michael J. Abrams Managing Director Aug. 16, 2016 M 42,097 0 0 $0
Mark Kowalski Sr VP & Chief Medical Officer March 15, 2016 A 0 0 $0
Roger Sawhney Director June 8, 2026 A 0 0 $0
Robert A Beardsley Director June 8, 2026 A 0 0 $0
Frank Torti Director Nov. 26, 2018 A 0 0 $0
Vivek Ramaswamy Director June 19, 2018 A 0 0 $0
Keith S Manchester Director June 19, 2018 A 0 0 $0
Daniel D Burgess Director June 19, 2018 A 0 0 $0
Herbert J Conrad Director June 19, 2018 A 0 0 $0
Richard C Henriques JR Director June 19, 2018 A 1,000 0 0 $0
Frank Karbe Director June 21, 2017 A 0 0 $0
Roivant Sciences Ltd. 10% owner Oct. 18, 2021 C 38,847,462 0 0 $0
Andrew Lo 10% owner Jan. 12, 2018 P 0 0 $0
Patrick Machado 10% owner Jan. 12, 2018 P 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 8 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Whitefort Capital Master Fund, LP, Whitefort Capital GP, LLC, Whitefort Capital Management, LP, Whitefort Capital Management GP, LLC, David Salanic, Joseph Kaplan ×5 filings April 28, 2026 8.00% Amendment SEC
Roivant Sciences Ltd. ×14 filings Feb. 25, 2025 20.50% Amendment SEC
Patrick Machado ×4 filings July 17, 2019 Initial filing SEC
Dr. Andrew Lo ×5 filings July 17, 2019 Initial filing SEC
QVT Financial LP, QVT Financial GP LLC, QVT Family Office Fund LP, QVT Associates GP LLC ×6 filings July 12, 2019 Initial filing SEC
SVF Investments (UK) Limited, SVF Holdings (UK) LLP, SoftBank Vision Fund L.P., SVF GP (Jersey) Limited ×4 filings July 12, 2019 Initial filing SEC
Dexxon Holdings Ltd., Dexcel Pharma Technologies Ltd., Dan Oren ×6 filings July 12, 2019 Initial filing SEC
Viking Global Investors LP, Viking Global Performance LLC, Viking Global Equities LP, Viking Global Equities II LP, VGE III Portfolio Ltd., Viking Global Equities Master Ltd., Viking Long Fund GP LLC, Viking Long Fund Master Ltd., Viking Global Opportunities GP LLC, Viking Global Opportunities Portfolio GP LLC, Viking Global Opportunities Illiquid Investments Sub-Master LP, O. Andreas Halvorsen, David C. Ott, Rose S. Shabet ×7 filings July 12, 2019 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 34 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
BBC · ETFis Series Trust I 0.66% 58,600 NS April 30, 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0.50% 24,523 SH Aug. 8, 2026 Daily
IWC · iShares Trust 0.17% 546,359 SH Aug. 8, 2026 Daily
LABU · Direxion Shares ETF Trust 0.11% 132,235 NS April 30, 2026 N-PORT
SMMV · iShares Trust 0.10% 62,236 SH Aug. 8, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.06% 10,748 SH Aug. 8, 2026 Daily
IBB · iShares Trust 0.06% 1,164,301 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.05% 172,487 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.04% 1,441,824 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.04% 7,110 NS May 31, 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0.03% 64,366 NS May 31, 2026 N-PORT
IWM · iShares Trust 0.02% 4,026,921 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.02% 925,044 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.02% 122,366 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.02% 65,520 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.02% 7,126 NS May 31, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.01% 734,401 NS May 31, 2026 N-PORT
ISCG · iShares Trust 0.01% 24,628 SH Aug. 8, 2026 Daily
ISCB · iShares Trust 0.01% 6,673 SH Aug. 8, 2026 Daily
UWM · ProShares Trust 0.01% 5,554 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.01% 1,810,587 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.01% 430,244 SH Aug. 8, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.01% 64,437 NS April 30, 2026 N-PORT
ISCV · iShares Trust 0.01% 13,314 SH Aug. 8, 2026 Daily
WSML · iShares Trust 0.01% 11,503 SH Aug. 8, 2026 Daily
URTY · ProShares Trust 0.01% 5,639 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 5,309 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 141 NS May 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 266,009 SH Aug. 8, 2026 Daily
IWV · iShares Trust 0.00% 49,253 SH Aug. 8, 2026 Daily
SCHB · SCHWAB STRATEGIC TRUST 0.00% 86,163 NS May 31, 2026 N-PORT
AVSC · AMERICAN CENTURY ETF TRUST 0.00% 4,760 NS May 31, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 5,034,547 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 13,683 SH Aug. 8, 2026 Daily